Alphavirus

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  Subject Areas on Research

  • An alphavirus vector overcomes the presence of neutralizing antibodies and elevated numbers of Tregs to induce immune responses in humans with advanced cancer. 
  • Development and preclinical evaluation of an alphavirus replicon particle vaccine for cytomegalovirus. 
  • Development and preclinical evaluation of an alphavirus replicon vaccine for influenza. 
  • Nonmucosal alphavirus vaccination stimulates a mucosal inductive environment in the peripheral draining lymph node. 
  • Novel recombinant alphaviral and adenoviral vectors for cancer immunotherapy.