Amides

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  Subject Areas on Research

  • A comparison of 0.5% bupivacaine, 0.5% ropivacaine, and 0.75% ropivacaine for interscalene brachial plexus block. 
  • A gap analysis approach to assess patient persistence with glaucoma medication. 
  • A photolabile ligand for light-activated release of caged copper. 
  • A tissue-engineered human trabecular meshwork hydrogel for advanced glaucoma disease modeling. 
  • Activation of adenylate cyclase by phosphoramidate and phosphonate analogs of GTP: possible role of covalent enzyme-substrate intermediates in the mechanism of hormonal activation. 
  • Ambulatory discharge after long-acting peripheral nerve blockade: 2382 blocks with ropivacaine. 
  • Anti-AIDS agents 49. Synthesis, anti-HIV, and anti-fusion activities of IC9564 analogues based on betulinic acid. 
  • Anxiety, vocalization, and agitation following peripheral nerve block with ropivacaine. 
  • Asparagine and glutamine: using hydrogen atom contacts in the choice of side-chain amide orientation. 
  • Bacteria Boost Mammalian Host NAD Metabolism by Engaging the Deamidated Biosynthesis Pathway. 
  • Base-boronated dinucleotides: synthesis and effect of N7-cyanoborane substitution on the base protons. 
  • Beneficial effects of the Rho kinase inhibitor Y27632 in murine puromycin aminonucleoside nephrosis. 
  • Bimatoprost 0.03% gel for cosmetic eyelash growth and enhancement. 
  • Bimatoprost, prostamide activity, and conventional drainage. 
  • Bimatoprost. 
  • Cellular basis for bimatoprost effects on human conventional outflow. 
  • Clinical profile and prognostic significance of natriuretic peptide trajectory following hospitalization for worsening chronic heart failure: findings from the ASTRONAUT trial. 
  • Clinical results in cachexia therapeutics. 
  • Combined lumbar-plexus and sciatic-nerve blocks: an analysis of plasma ropivacaine concentrations. 
  • Compounds from Sichuan and Melegueta peppers activate, covalently and non-covalently, TRPA1 and TRPV1 channels. 
  • Conjunctival hyperemia associated with bimatoprost use: a histopathologic study. 
  • Conserved Mechanism of 2'-Phosphorylation-Aided Amide Ligation in Peptidyl Nucleoside Biosynthesis. 
  • Continuous peripheral nerve block for ambulatory surgery. 
  • Contralateral local anesthetic spread from an outpatient interscalene catheter. 
  • Control of basement membrane remodeling and epithelial branching morphogenesis in embryonic lung by Rho and cytoskeletal tension. 
  • Copper-Catalyzed Modular Amino Oxygenation of Alkenes: Access to Diverse 1,2-Amino Oxygen-Containing Skeletons. 
  • Copper-catalyzed electrophilic amination of heteroarenes and arenes by C-H zincation. 
  • Copper-mediated amidation of heterocyclic and aromatic C-H bonds. 
  • Cyclic mechanical stress and trabecular meshwork cell contractility. 
  • Cytogenetic changes induced by 1-(N1-methylhydrazinomethyl)-N-isopropyl benzamide in Ehrlich ascites tumor cells. 
  • Design and synthesis of novel imidazole-substituted dipeptide amides as potent and selective inhibitors of Candida albicans myristoylCoA:protein N-myristoyltransferase and identification of related tripeptide inhibitors with mechanism-based antifungal activity. 
  • Differential effects of prostaglandin E2-sensitive receptors on contractility of human ocular cells that regulate conventional outflow. 
  • Difluoroethylamines as an amide isostere in inhibitors of cathepsin K. 
  • Direct and Selective 3-Amidation of Indoles Using Electrophilic N-[(Benzenesulfonyl)oxy]amides. 
  • Discovery of substituted 4-(pyrazol-4-yl)-phenylbenzodioxane-2-carboxamides as potent and highly selective Rho kinase (ROCK-II) inhibitors. 
  • Effect of aliskiren on post-discharge outcomes among diabetic and non-diabetic patients hospitalized for heart failure: insights from the ASTRONAUT trial. 
  • Effect of aliskiren on postdischarge mortality and heart failure readmissions among patients hospitalized for heart failure: the ASTRONAUT randomized trial. 
  • Effect of bimatoprost on intraocular pressure in prostaglandin FP receptor knockout mice. 
  • Effects of Y27632 on keratinocyte procurement and wound healing. 
  • Effects of ZD6169, a K ATP channel opener, on neurally-mediated plasma extravasation in the rat urinary bladder induced by chemical or electrical stimulation of nerves. 
  • Efficacy of intravesical ropivacaine injection on urinary symptoms following ureteral stenting: a randomized, controlled study. 
  • Enhanced protein flexibility caused by a destabilizing amino acid replacement in BPTI. 
  • Evidence-Based Guidelines Should Be Used To Inform COVID-19 Management. 
  • Extremely prolonged unilateral block (20 hours) with spinal ropivacaine used for cervical cerclage placement. 
  • Fast acquisition of high resolution 4-D amide-amide NOESY with diagonal suppression, sparse sampling and FFT-CLEAN. 
  • Functionalized indoleamines as potent, drug-like inhibitors of isoprenylcysteine carboxyl methyltransferase (Icmt). 
  • High-resolution, noninvasive longitudinal live imaging of immune responses. 
  • Improved speciation of dissolved organic nitrogen in natural waters: amide hydrolysis with fluorescence derivatization. 
  • Increased periocular pigmentation with ocular hypotensive lipid use in African Americans. 
  • Induction of apoptotic cell death and prevention of tumor growth by ceramide analogues in metastatic human colon cancer. 
  • Influence of actin cytoskeletal integrity on matrix metalloproteinase-2 activation in cultured human trabecular meshwork cells. 
  • Influence of atrial fibrillation on post-discharge natriuretic peptide trajectory and clinical outcomes among patients hospitalized for heart failure: insights from the ASTRONAUT trial. 
  • Influence of denaturing agents on solvent structure. 
  • Inhibition of Rho-kinase induces alphaB-crystallin expression in lens epithelial cells. 
  • Interscalene brachial plexus block with a continuous catheter insertion system and a disposable infusion pump. 
  • Interscalene brachial plexus block with continuous intraarticular infusion of ropivacaine. 
  • Isolation and insecticidal activity of mellamide from Aspergillus melleus. 
  • Kinetics of irreversible activation of adenylate cyclase of fat cell membranes by phosphonium and phosphoramidate analogs of gtp1. 
  • Local anesthetics and mode of delivery: bupivacaine versus ropivacaine versus levobupivacaine. 
  • Low interscalene block provides reliable anesthesia for surgery at or about the elbow. 
  • Lumbar plexus and sciatic nerve block for knee arthroplasty: comparison of ropivacaine and bupivacaine. 
  • Minimum effective dose of spinal ropivacaine with and without fentanyl for postpartum tubal ligation. 
  • Model synthesis of nucleoside boranophosphoramidate with amino acid for prodrug purpose. 
  • Modulation of aqueous humor outflow facility by the Rho kinase-specific inhibitor Y-27632. 
  • Motor blocking minimum local anesthetic concentrations of bupivacaine, levobupivacaine, and ropivacaine in labor. 
  • Paradoxical intraocular pressure elevation after combined therapy with latanoprost and bimatoprost. 
  • Patient-reported symptoms during and after direct-acting antiviral therapies for chronic hepatitis C: The PROP UP study. 
  • Plasma renin activity, response to aliskiren, and clinical outcomes in patients hospitalized for heart failure: the ASTRONAUT trial. 
  • Posterior capsular injections of ropivacaine during total knee arthroplasty: a randomized, double-blind, placebo-controlled study. 
  • Probing the folding and unfolding dynamics of secondary and tertiary structures in a three-helix bundle protein. 
  • Rapid assignment of protein side chain resonances using projection-reconstruction of (4,3)D HC(CCO)NH and intra-HC(C)NH experiments. 
  • Rare coding variants and X-linked loci associated with age at menarche. 
  • Regulation of cofilin phosphorylation in glomerular podocytes by testis specific kinase 1 (TESK1). 
  • Relationship between timing of trial randomization, protocol completion, and clinical outcomes among patients hospitalized for heart failure: from the ASTRONAUT trial. 
  • Rho A/Rho kinase: human umbilical artery mRNA expression in normal and pre eclamptic pregnancies and functional role in isoprostane-induced vasoconstriction. 
  • Rho kinase promotes alloimmune responses by regulating the proliferation and structure of T cells. 
  • Selective α-amination and α-acylation of esters and amides via dual reactivity of O-acylhydroxylamines toward zinc enolates. 
  • Small-dose intrathecal lidocaine versus ropivacaine for anorectal surgery in an ambulatory setting. 
  • Stanniocalcin-1 Is an Ocular Hypotensive Agent and a Downstream Effector Molecule That Is Necessary for the Intraocular Pressure-Lowering Effects of Latanoprost. 
  • Statins inhibit toll-like receptor 4-mediated lipopolysaccharide signaling and cytokine expression. 
  • Successful resuscitation after ropivacaine-induced ventricular fibrillation. 
  • Synthesis and Anticancer Activity of Tertiary Amides of Salinomycin and Their C20-oxo Analogues. 
  • Synthesis of nucleoside boranophosphoramidate prodrugs conjugated with amino acids. 
  • The difficulties of ambulatory interscalene and intra-articular infusions for rotator cuff surgery: a preliminary report. 
  • The effect of Rho-associated kinase inhibition on the ocular penetration of timolol maleate. 
  • The effect of stimulating versus conventional perineural catheters on postoperative analgesia following ultrasound-guided femoral nerve localization. 
  • The integrin-linked kinase regulates cell morphology and motility in a rho-associated kinase-dependent manner. 
  • The synthesis and secretion of gamma-globulin by lymph node cells. V. The dissociation of the microsome-antibody complex with enzymatically and chemically altered gamma-globulins. 
  • Therapy and clinical trials. 
  • Tissue ablation by a free-electron laser tuned to the amide II band. 
  • Tunable molecular tension sensors reveal extension-based control of vinculin loading. 
  • Vascular smooth muscle cell migration induced by domains of thrombospondin-1 is differentially regulated. 
  • β-Arrestin-2-Dependent Signaling Promotes CCR4-mediated Chemotaxis of Murine T-Helper Type 2 Cells.