Amino Acid Oxidoreductases

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  Subject Areas on Research

  • Analysis of LOXL1 polymorphisms in a United States population with pseudoexfoliation glaucoma. 
  • Analysis of responses to bradykinin in the pulmonary vascular bed of the cat. 
  • Benzoate treatment and the glycine index in nonketotic hyperglycinaemia. 
  • Biochemistry of nitric oxide and its redox-activated forms. 
  • Biosynthesis of nitric oxide and citrulline from L-arginine by constitutive nitric oxide synthase present in rabbit corpus cavernosum. 
  • Cold-induced brain edema in mice. Involvement of extracellular superoxide dismutase and nitric oxide. 
  • Comparative effects of L-NNA and alkyl esters of L-NNA on pulmonary vasodilator responses to ACh, BK, and SP. 
  • Constitutive and inducible nitric oxide synthase gene expression, regulation, and activity in human lung epithelial cells. 
  • Cytochrome P450IIIA activity and cytokine-mediated synthesis of nitric oxide. 
  • Cytokine-mediated production of nitric oxide in isolated rat hepatocytes is dependent on cytochrome P-450III activity. 
  • Endothelial type nitric oxide synthase in skeletal muscle fibers: mitochondrial relationships. 
  • Enhanced colonic nitric oxide generation and nitric oxide synthase activity in ulcerative colitis and Crohn's disease. 
  • Enhanced gastric nitric oxide synthase activity in duodenal ulcer patients. 
  • Gene therapy inhibiting neointimal vascular lesion: in vivo transfer of endothelial cell nitric oxide synthase gene. 
  • Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci. 
  • Genetic variants and cellular stressors associated with exfoliation syndrome modulate promoter activity of a lncRNA within the LOXL1 locus. 
  • Genetics of adult glaucoma. 
  • Genetics of pseudoexfoliation syndrome. 
  • Human mononuclear phagocyte inducible nitric oxide synthase (iNOS): analysis of iNOS mRNA, iNOS protein, biopterin, and nitric oxide production by blood monocytes and peritoneal macrophages. 
  • Induction of nitric oxide synthase in demyelinating regions of multiple sclerosis brains. 
  • Inhibition of nitric oxide synthase increases extracellular cerebral glutamate concentration after global ischemia. 
  • Inhibition of nitric oxide synthesis attenuates alcohol consumption in two strains of alcohol-preferring rats. 
  • Inhibition of sphincter of Oddi function by the nitric oxide carrier S-nitroso-N-acetylcysteine in rabbits and humans. 
  • Interleukin 1-induced production of nitric oxide inhibits benzenetriol-mediated oxidative injury in rat hepatocytes. 
  • L-amino acid oxidase (LOX) modulation of melphalan activity against intracranial glioma. 
  • L-arginine enhances injury in the isolated rabbit lung during hyperoxia. 
  • LOXL1 expression in lens capsule tissue specimens from individuals with pseudoexfoliation syndrome and glaucoma. 
  • Lack of association between LOXL1 gene polymorphisms and primary open angle glaucoma in the Saudi Arabian population. 
  • Lack of association between LOXL1 variants and primary open-angle glaucoma in three different populations. 
  • Major LOXL1 risk allele is reversed in exfoliation glaucoma in a black South African population. 
  • Major review: Exfoliation syndrome; advances in disease genetics, molecular biology, and epidemiology. 
  • Nitric oxide in skeletal muscle. 
  • Nitric oxide is required for tactile learning in Octopus vulgaris. 
  • Nitric oxide produced by human B lymphocytes inhibits apoptosis and Epstein-Barr virus reactivation. 
  • Nitric oxide regulates basal systemic and pulmonary vascular resistance in healthy humans. 
  • Nitric oxide synthase from cerebellum catalyzes the formation of equimolar quantities of nitric oxide and citrulline from L-arginine. 
  • Nitric oxide synthase in human and rat lung: immunocytochemical and histochemical localization. 
  • Nitric oxide synthase inhibition and extracellular glutamate concentration after cerebral ischemia/reperfusion. 
  • Nitric oxide synthase inhibition irreversibly decreases perfusion in the R3230Ac rat mammary adenocarcinoma. 
  • Pigment formation from L-tryptophan by a particulate fraction from an Achromobacter species. 
  • Role of nitric oxide in human esophageal circular smooth muscle in vitro. 
  • Selective activation and inhibition of calmodulin-dependent enzymes by a calmodulin-like protein found in human epithelial cells. 
  • Simtuzumab Is Ineffective for Patients With Bridging Fibrosis or Compensated Cirrhosis Caused by Nonalcoholic Steatohepatitis. 
  • Superoxide dismutase potentiates platelet-activating factor-induced injury in perfused lung. 
  • The biology of nitrogen oxides in the airways. 
  • The dose-related effects of nitric oxide synthase inhibition on cerebral blood flow during isoflurane and pentobarbital anesthesia. 
  • The effect of L-amino acid oxidase on activity of melphalan against an intracranial xenograft. 
  • The role of lysyl oxidase-like 1 DNA copy number variants in exfoliation glaucoma. 
  • The role of nitric oxide in the pathogenesis of spontaneous murine autoimmune disease: increased nitric oxide production and nitric oxide synthase expression in MRL-lpr/lpr mice, and reduction of spontaneous glomerulonephritis and arthritis by orally administered NG-monomethyl-L-arginine. 
  • Tumor necrosis factor-alpha (TNF-alpha) stimulates mucin secretion and gene expression in airway epithelium in vitro. 
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  Keywords of People

  • Liu, Yutao, Adjunct Assistant Professor in the Department of Medicine, Medicine, Medical Genetics