Amino Acyl-tRNA Synthetases
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Subject Areas on Research
- A minimal TrpRS catalytic domain supports sense/antisense ancestry of class I and II aminoacyl-tRNA synthetases.
- A single base substitution in the variable pocket of yeast tRNA(Arg) eliminates species-specific aminoacylation.
- Alteration of aminoacyl-tRNA synthetase activities by phosphorylation with casein kinase I.
- Elucidating the path to Plasmodium prolyl-tRNA synthetase inhibitors that overcome halofuginone resistance.
- Functional Class I and II Amino Acid-activating Enzymes Can Be Coded by Opposite Strands of the Same Gene.
- Identification of three protein kinases which phosphorylate threonyl-tRNA synthetase from rat liver.
- Proteome-Wide Characterization of Phosphorylation-Induced Conformational Changes in Breast Cancer.
- Regulation of phosphorylation of aminoacyl-tRNA synthetases in the high molecular weight core complex in reticulocytes.
- Regulation of protein synthesis by phosphorylation of ribosomal protein S6 and aminoacyl-tRNA synthetases.
- Statistical evaluation of the Rodin-Ohno hypothesis: sense/antisense coding of ancestral class I and II aminoacyl-tRNA synthetases.
- The Rodin-Ohno hypothesis that two enzyme superfamilies descended from one ancestral gene: an unlikely scenario for the origins of translation that will not be dismissed.
- The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs.