Transaminases

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  Subject Areas on Research

  • A mathematical model of tryptophan metabolism via the kynurenine pathway provides insights into the effects of vitamin B-6 deficiency, tryptophan loading, and induction of tryptophan 2,3-dioxygenase on tryptophan metabolites. 
  • A new syndrome: ascites, hyperbilirubinemia, and hypoalbuminemia after biochemical modulation of fluorouracil with N-phosphonacetyl-L-aspartate (PALA) 
  • Amiodarone hepatotoxicity simulating alcoholic liver disease. 
  • BCAT1 and miR-2504: novel methylome signature distinguishes spindle/desmoplastic melanoma from superficial malignant peripheral nerve sheath tumor. 
  • Branched chain amino acid transaminase 1 (BCAT1) is overexpressed and hypomethylated in patients with non-alcoholic fatty liver disease who experience adverse clinical events: A pilot study. 
  • Branched-Chain Aminotransferases Control TORC1 Signaling in Saccharomyces cerevisiae. 
  • Buprenorphine/Naloxone and methadone effects on laboratory indices of liver health: a randomized trial. 
  • Cholestatic hepatitis from erythromycin ethylsuccinate. Report of two cases. 
  • Clinical microbiological case: severe relapsing septal panniculitis in a healthy man from the south-eastern USA. 
  • Cross circulation between children in hepatic coma and chimpanzees. Clinical, biochemical, and coagulation observations. 
  • ENU mutagenesis identifies mice with mitochondrial branched-chain aminotransferase deficiency resembling human maple syrup urine disease. 
  • Efficacy and tolerability of lovastatin in 3390 women with moderate hypercholesterolemia. 
  • Glutamine metabolism during aerial mycelium growth of Neurospora crassa. 
  • Hepatic complications of obesity. 
  • In vivo and in vitro examination of stability of primary hyperoxaluria-associated human alanine:glyoxylate aminotransferase. 
  • Intrahepatic cholestasis of pregnancy with marked elevation of transaminases in a black American. 
  • Liver fibrosis during clinical ascertainment of glycogen storage disease type III: a need for improved and systematic monitoring. 
  • Low prevalence of chronic hepatitis C, but high prevalence of elevated aminotransferases in a cohort of 2026 patients referred for orthopaedic surgery in the eastern part of Germany. 
  • Metformin reverses fatty liver disease in obese, leptin-deficient mice. 
  • Molecular function prediction for a family exhibiting evolutionary tendencies toward substrate specificity swapping: recurrence of tyrosine aminotransferase activity in the Iα subfamily. 
  • Nonalcoholic fatty liver disease: an underrecognized cause of cryptogenic cirrhosis. 
  • Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer. 
  • P-Selectin mediates reperfusion injury through neutrophil and platelet sequestration in the warm ischemic mouse liver. 
  • Phase I study of intraperitoneal recombinant human interleukin 12 in patients with Müllerian carcinoma, gastrointestinal primary malignancies, and mesothelioma. 
  • Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis. 
  • Platelet gamma-aminobutyrate-alpha-ketoglutarate transaminase (GABA-T) in schizophrenia. 
  • Polycystic ovary syndrome and severe nonalcoholic steatohepatitis: beneficial effect of modest weight loss and exercise on liver biopsy findings. 
  • Protective effects of ischemic preconditioning for liver resection performed under inflow occlusion in humans. 
  • Pyridoxine deficiency and ethanol-induced liver injury. 
  • Relation of circulating liver transaminase concentrations to risk of new-onset atrial fibrillation. 
  • Review of the use of hepatitis B core antibody-positive kidney donors. 
  • Stereochemical recognition of doubly functional aminotransferase in 2-deoxystreptamine biosynthesis. 
  • Sympathetic nervous system inhibition increases hepatic progenitors and reduces liver injury. 
  • Thermodynamics of reactions catalyzed by PABA synthase. 
  • Transcriptional polarity enhances the contribution of the internal promoter, ilvEp, in the expression of the ilvGMEDA operon in wild-type Escherichia coli K12. 
  • Treatment of chronic hepatitis C with interferon with or without ursodeoxycholic acid: a randomized prospective trial. 
  • ULTRAVIOLET ROTATORY DISPERSION OF ASPARTIC AMINOTRANSFERASE. 
  • [Acute hepatitis B: is antiviral therapy indicated? Two case reports]. 
  • [Increase of two hepatic transaminases considered as an enzymatic adaptation in the rat on a meat diet]. 
  • [Influence of meat diet on the activity of seven hepatic enzymes in rats; increase of transaminases as an example of enzymatic adaptation].