Analgesia

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  Subject Areas on Research

  • A greater analgesia, sedation, delirium order set quality score is associated with a decreased duration of mechanical ventilation in cardiovascular surgery patients. 
  • A pharmacodynamic model to investigate the structure-activity profile of a series of novel opioid analgesics. 
  • A pilot clinical trial of the cholecystokinin receptor antagonist MK-329 in patients with advanced pancreatic cancer. 
  • A randomized controlled comparison of electro-acupoint stimulation or ondansetron versus placebo for the prevention of postoperative nausea and vomiting. 
  • A snapshot of children's postoperative tonsillectomy outcomes at home 
  • Ambulatory continuous interscalene nerve blocks decrease the time to discharge readiness after total shoulder arthroplasty: a randomized, triple-masked, placebo-controlled study. 
  • Ambulatory surgery with long acting regional anesthesia. 
  • American College of Chest Physicians consensus statement on the use of topical anesthesia, analgesia, and sedation during flexible bronchoscopy in adult patients. 
  • An over-the-counter central sensitization therapy: a chronic back pain registry study of pain relief, medication use and their adverse effects. 
  • Analgesia and Sedation Requirements in Mechanically Ventilated Trauma Patients With Acute, Preinjury Use of Cocaine and/or Amphetamines. 
  • Analgesia in Athletes: A Review of Commonly Used Oral and Injectable Modalities. 
  • Anesthesia and Analgesia for the Obese Parturient. 
  • Association between hospital volume and network membership and an analgesia, sedation and delirium order set quality score: a cohort study. 
  • Auriculotherapy for pain management: a systematic review and meta-analysis of randomized controlled trials. 
  • Brachial Plexus Block with Liposomal Bupivacaine for Shoulder Surgery Improves Analgesia and Reduces Opioid Consumption: Results from a Multicenter, Randomized, Double-Blind, Controlled Trial. 
  • Case reports: two cases of glenohumeral chondrolysis after intraarticular pain pumps. 
  • Clinical policy: procedural sedation and analgesia in the emergency department. 
  • Determining Brain Mechanisms that Underpin Analgesia Induced by the Use of Pain Coping Skills. 
  • Development and longitudinal validation of the overall benefit of analgesia score: a simple multi-dimensional quality assessment instrument. 
  • Differential effects of experimental central sensitization on the time-course and magnitude of offset analgesia. 
  • Distinct brain mechanisms support spatial vs temporal filtering of nociceptive information. 
  • Distinct neuronal populations in the basolateral and central amygdala are activated with acute pain, conditioned fear, and fear-conditioned analgesia. 
  • Duloxetine for the reduction of opioid use in elective orthopedic surgery: a systematic review and meta-analysis. 
  • Effect of Multimodal Analgesia on Opioid Use After Open Ventral Hernia Repair. 
  • Effect of pain management on immunization efficacy in mice. 
  • Effects of nociceptin (13-17) in pain modulation at supraspinal level in mice. 
  • Emergency department analgesia without narcotics for adults with acute sickle cell pain crisis: case reports and review of crisis management. 
  • Enhanced Recovery After Surgery and Multimodal Strategies for Analgesia. 
  • Enhanced morphine analgesia in mice lacking beta-arrestin 2. 
  • Epidural fentanyl, with and without epinephrine for post-Caesarean section analgesia. 
  • Evolving the management of acute perioperative pain towards opioid free protocols: a narrative review. 
  • Human carbonic anhydrase-8 AAV8 gene therapy inhibits nerve growth factor signaling producing prolonged analgesia and anti-hyperalgesia in mice. 
  • Impact of a Real-Time, Pharmacist-Led, Intensive Care Unit-Based Feedback Intervention on Analgesia and Sedation Quality Among Mechanically Ventilated Patients. 
  • Implementation of a Multimodal Analgesia Protocol Among Outpatient Neurosurgical Patients Undergoing Spine Surgery to Improve Patient Outcomes. 
  • Improving the Care of Individuals With Sickle Cell Disease in the Emergency Department Using a Quality Improvement Framework: The Emergency Department Sickle Cell Assessment of Needs and Strengths (ED-SCANS). 
  • Incidence, patient satisfaction, and perceptions of post-surgical pain: results from a US national survey. 
  • Intraarticular analgesia in shoulder surgery. 
  • Intrathecal morphine for postpartum bilateral tubal ligation. 
  • Introduction of an Analgesia Prescription Guideline Can Reduce Unused Opioids After Cardiac Surgery: A Before and After Cohort Study. 
  • Ion channels in analgesia research. 
  • Laparoscopic donor nephrectomy increases the supply of living donor kidneys: a center-specific microeconomic analysis. 
  • Light versus heavy sedation after cardiac surgery: myocardial ischemia and the stress response. Maritime Heart Centre and Dalhousie University. 
  • Managing painful procedures in children with cancer. 
  • Melanocortin-1 receptor gene variants affect pain and mu-opioid analgesia in mice and humans. 
  • Motor cortex stimulation and neuropathic facial pain. 
  • Multimodal Perioperative Analgesia Regimen to Improve Patient Outcomes After Total Knee Arthroplasty: A Multidisciplinary Quality Improvement Project. 
  • Multimodal analgesia using opioid-sparing regimen in patients undergoing left ventricular assist device implantation. 
  • Music meets surgery: two sides to the art of "healing". 
  • Oral Multimodal Analgesia for Total Joint Arthroplasty. 
  • PD-L1 inhibits acute and chronic pain by suppressing nociceptive neuron activity via PD-1. 
  • Pain Management for Orthopedic Injuries. 
  • Pain Phenotypes and Associated Clinical Risk Factors Following Traumatic Amputation: Results from Veterans Integrated Pain Evaluation Research (VIPER). 
  • Pain diaries. For providers, nuanced data; for patients, a sense of control. 
  • Paresthesias and EEG potentials evoked by stimulation of the dorsal funiculi in man. 
  • Pectoralis-II Myofascial Block and Analgesia: Comment. 
  • Post-Thoracotomy Pain: Current Strategies for Prevention and Treatment. 
  • Postoperative analgesia after cesarean delivery. 
  • Quadratus lumborum block for postoperative analgesia after cesarean delivery: A systematic review with meta-analysis and trial-sequential analysis. 
  • Quantitative trait locus and computational mapping identifies Kcnj9 (GIRK3) as a candidate gene affecting analgesia from multiple drug classes. 
  • Renal response following perioperative ketorolac analgesia in living kidney donation. 
  • Reply. 
  • Reversion mutation of cDNA CA8-204 minigene construct produces a truncated functional peptide that regulates calcium release in vitro and produces profound analgesia in vivo. 
  • STING controls nociception via type I interferon signalling in sensory neurons. 
  • Safety in Acute Pain Medicine-Pharmacologic Considerations and the Impact of Systems-Based Gaps. 
  • Self-efficacy for managing pain, symptoms, and function in patients with lung cancer and their informal caregivers: associations with symptoms and distress. 
  • Short small-interfering RNAs produce interferon-α-mediated analgesia. 
  • Simplified pain-control protocol after uterine artery embolization. 
  • Somatosensory cortical signature of facial nociception and vibrotactile touch-induced analgesia. 
  • Standardizing postoperative PICU handovers improves handover metrics and patient outcomes. 
  • Structure-activity relationships of noreperidine congeners on cholinesterase systems in vitro and analgesia in vivo. 
  • T-Cell Mediation of Pregnancy Analgesia Affecting Chronic Pain in Mice. 
  • TRPM8 is the principal mediator of menthol-induced analgesia of acute and inflammatory pain. 
  • The effect of mixing 1.5% mepivacaine and 0.5% bupivacaine on duration of analgesia and latency of block onset in ultrasound-guided interscalene block. 
  • The relative analgesic value of a femoral nerve block versus adductor canal block following total knee arthroplasty: a randomized, controlled, double-blinded study. 
  • The role of gabapentinoids in acute and chronic pain after surgery. 
  • The sequence of administration of 1.5% mepivacaine and 0.5% bupivacaine does not affect latency of block onset or duration of analgesia in ultrasound-guided interscalene block. 
  • Total ankle arthroplasty and perioperative pain. 
  • Transdermal nicotine for analgesia after radical retropubic prostatectomy. 
  • Ultrasound-guided percutaneous peripheral nerve stimulation for analgesia following total knee arthroplasty: a prospective feasibility study. 
  • Use of bulleyaconitine A as an adjuvant for prolonged cutaneous analgesia in the rat. 
  • Use of local anesthetic a key tenet in multimodal analgesia to modulate chronic post-mastectomy pain. 
  • Virtual Reality Analgesia in Labor: The VRAIL Pilot Study-A Preliminary Randomized Controlled Trial Suggesting Benefit of Immersive Virtual Reality Analgesia in Unmedicated Laboring Women. 
  • What's new in obstetric anesthesia in 2017? 
  • Xenon and sevoflurane provide analgesia during labor and fetal brain protection in a perinatal rat model of hypoxia-ischemia. 
  • [Analgesic effect of intrathecal injection of Herpes simplex virus type I amplicon vector-mediated human preproenkephalin gene on chronic neuropathic pain: experiment with rats]. 
  • [Three subanaesthetic dose ketamines mixed with butorphanol in the postoperative continuous intravenous analgesia]. 
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  Keywords of People

  • Jordt, Sven Eric, Associate Professor in Anesthesiology, Pharmacology & Cancer Biology
  • Miller, Timothy Ellis, Professor of Anesthesiology, Anesthesiology, General, Vascular, High Risk Transplant & Critical Care
  • Nielsen, Karen Cristina, Associate Professor of Anesthesiology, Anesthesiology, Ambulatory