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Subject Areas on Research
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5α-Reductase inhibition coupled with short off cycles increases survival in the LNCaP xenograft prostate tumor model on intermittent androgen deprivation therapy.
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A Nomogram for Testosterone Recovery After Combined Androgen Deprivation and Radiation Therapy for Prostate Cancer.
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A glutaminase isoform switch drives therapeutic resistance and disease progression of prostate cancer.
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A lifestyle intervention of weight loss via a low-carbohydrate diet plus walking to reduce metabolic disturbances caused by androgen deprivation therapy among prostate cancer patients: carbohydrate and prostate study 1 (CAPS1) randomized controlled trial.
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A new prostate cancer therapeutic approach: combination of androgen ablation with COX-2 inhibitor.
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A randomized controlled trial comparing changes in fitness with or without supervised exercise in patients initiated on enzalutamide and androgen deprivation therapy for non-metastatic castration-sensitive prostate cancer (EXTEND).
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A role for the androgen receptor in the treatment of male breast cancer.
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ADT risks and side effects in advanced prostate cancer: cardiovascular and acute renal injury.
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ARCHES: A Randomized, Phase III Study of Androgen Deprivation Therapy With Enzalutamide or Placebo in Men With Metastatic Hormone-Sensitive Prostate Cancer.
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Abiraterone acetate for patients with metastatic castration-resistant prostate cancer progressing after chemotherapy: final analysis of a multicentre, open-label, early-access protocol trial.
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Acetylcholinesterase Inhibitors Are Associated with Reduced Fracture Risk among Older Veterans with Dementia.
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Activation of mitogen-activated protein kinase pathway by the antiandrogen hydroxyflutamide in androgen receptor-negative prostate cancer cells.
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Adjuvant radiation therapy, androgen deprivation, and docetaxel for high-risk prostate cancer postprostatectomy: Results of NRG Oncology/RTOG study 0621.
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Adrenal androgen levels as predictors of outcome in prostate cancer patients treated with ketoconazole plus antiandrogen withdrawal: results from a cancer and leukemia group B study.
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American Society for Radiation Oncology (ASTRO) and American College of Radiology (ACR) practice guideline for the transperineal permanent brachytherapy of prostate cancer.
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An interdomain interaction of the androgen receptor is required for its aggregation and toxicity in spinal and bulbar muscular atrophy.
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An intergenerational androgenic mechanism of female intrasexual competition in the cooperatively breeding meerkat.
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Androgen Deprivation Monotherapy for Localized Prostate Cancer: Can It Be Justified?
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Androgen Receptor Splice Variant, AR-V7, as a Biomarker of Resistance to Androgen Axis-Targeted Therapies in Advanced Prostate Cancer.
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Androgen Receptor Targeted Treatments of Prostate Cancer: 35 Years of Progress with Antiandrogens.
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Androgen and androgen receptor antagonist responsive primary African-American benign prostate epithelial cell line.
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Androgen deprivation therapy and cardiovascular disease.
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Androgen deprivation therapy and depression in men with prostate cancer treated with definitive radiation therapy.
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Androgen deprivation therapy for prostate cancer results in significant loss of bone density.
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Androgen deprivation therapy for the treatment of prostate cancer: a focus on pharmacokinetics
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Androgen receptor mutations in androgen-independent prostate cancer: Cancer and Leukemia Group B Study 9663.
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Androgen receptor mutations in patients with castration-resistant prostate cancer treated with apalutamide.
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Androgen-deprivation therapy and metabolic syndrome in men with prostate cancer.
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Androgen-deprivation therapy-induced aggressive prostate cancer with neuroendocrine differentiation.
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Androgens and masculinization of genitalia in the spotted hyaena (Crocuta crocuta). 2. Effects of prenatal anti-androgens.
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Antiandrogen withdrawal alone or in combination with ketoconazole in androgen-independent prostate cancer patients: a phase III trial (CALGB 9583).
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Association Between Androgen Deprivation Therapy and Mortality Among Patients With Prostate Cancer and COVID-19.
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Association of Androgen Deprivation Therapy With Dementia in Men With Prostate Cancer Who Receive Definitive Radiation Therapy.
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Association of Presalvage Radiotherapy PSA Levels After Prostatectomy With Outcomes of Long-term Antiandrogen Therapy in Men With Prostate Cancer.
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Azacitidine favorably modulates PSA kinetics correlating with plasma DNA LINE-1 hypomethylation in men with chemonaïve castration-resistant prostate cancer.
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Baseline cardiovascular risk assessment in cancer patients scheduled to receive cardiotoxic cancer therapies: a position statement and new risk assessment tools from the Cardio-Oncology Study Group of the Heart Failure Association of the European Society of Cardiology in collaboration with the International Cardio-Oncology Society.
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Biochemical recurrence after definitive prostate cancer therapy. Part II: treatment strategies for biochemical recurrence of prostate cancer.
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Biochemical recurrence of prostate cancer.
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Body composition, physical function and quality of life in healthy men and across different stages of prostate cancer.
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Bone health in prostate cancer patients receiving androgen-deprivation therapy: the role of bisphosphonates.
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CSF1 receptor targeting in prostate cancer reverses macrophage-mediated resistance to androgen blockade therapy.
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Cancer and Leukemia Group B 90203 (Alliance): Radical Prostatectomy With or Without Neoadjuvant Chemohormonal Therapy in Localized, High-Risk Prostate Cancer.
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Carcinoma of the prostate: the therapeutic dilemma.
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Changes in bone health and skeletal-related events following implementation of a multidisciplinary consensus statement guiding surveillance and treatment of men undergoing androgen deprivation therapy for prostate cancer.
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Changes in initial treatment for prostate cancer among Medicare beneficiaries, 1999-2007.
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Clinical outcomes by age in men with hormone refractory prostate cancer: a pooled analysis of 8 Cancer and Leukemia Group B (CALGB) studies.
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Clinical phenotypes of castration-resistant prostate cancer.
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Combination external beam radiation and brachytherapy boost with androgen deprivation for treatment of intermediate-risk prostate cancer: long-term results of CALGB 99809.
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Combination hormonal therapy: a reassessment within advanced prostate cancer.
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Combination of Radiation Therapy and Short-Term Androgen Blockade With Abiraterone Acetate Plus Prednisone for Men With High- and Intermediate-Risk Localized Prostate Cancer.
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Combination of low-dose flutamide and finasteride for PSA-only recurrent prostate cancer after primary therapy.
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Combined low-dose flutamide plus finasteride vs low-dose flutamide monotherapy for recurrent prostate cancer: a comparative analysis of two phase II trials with a long-term follow-up.
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Comparison of Systemic Treatments for Metastatic Castration-Sensitive Prostate Cancer: A Systematic Review and Network Meta-analysis.
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Comprehensive serial molecular profiling of an "N of 1" exceptional non-responder with metastatic prostate cancer progressing to small cell carcinoma on treatment.
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Considerations Regarding a Network Meta-analysis of Systemic Treatments for Metastatic Castration-Sensitive Prostate Cancer-Reply.
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Controversies in the treatment of prostate cancer with maximal androgen deprivation.
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Cost-Effectiveness of Primary Radiation Therapy Versus Radical Prostatectomy for Intermediate- to High-Risk Prostate Cancer.
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Cost-Effectiveness of Systemic Treatments for Metastatic Castration-Sensitive Prostate Cancer: An Economic Evaluation Based on Network Meta-Analysis.
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Cost-effective models for flutamide for prostate carcinoma patients: are they helpful to policy makers?
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Development and validation of a prognostic model for overall survival in chemotherapy-naïve men with metastatic castration-resistant prostate cancer.
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Development and validation of circulating tumour cell enumeration (Epic Sciences) as a prognostic biomarker in men with metastatic castration-resistant prostate cancer.
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Differences in Toxicity and Outcomes in Clinical Trial Participants From Minority Populations.
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Docetaxel for advanced prostate cancer: how early to start?
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Does race predict the development of metastases in men who receive androgen-deprivation therapy for a biochemical recurrence after radical prostatectomy?
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EGFR-upregulated LIFR promotes SUCLG2-dependent castration resistance and neuroendocrine differentiation of prostate cancer.
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Early prostate cancer: prevention, treatment modalities, and quality of life issues.
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Early prostate cancer: the national results of radiation treatment from the Patterns of Care and Radiation Therapy Oncology Group studies with prospects for improvement with conformal radiation and adjuvant androgen deprivation.
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Early versus delayed hormonal therapy for prostate specific antigen only recurrence of prostate cancer after radical prostatectomy.
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Editor' summary: A paradigm shift in castration-resistant prostate cancer management.
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Effect of Androgen Deprivation Therapy on Metabolic Complications and Cardiovascular Risk.
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Effect of Enzalutamide plus Androgen Deprivation Therapy on Health-related Quality of Life in Patients with Metastatic Hormone-sensitive Prostate Cancer: An Analysis of the ARCHES Randomised, Placebo-controlled, Phase 3 Study.
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Effects of neoadjuvant hormonal therapy on prostate biopsy results after (125)I and (103)Pd seed implantation.
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Effects of prenatal treatment with antiandrogens on luteinizing hormone secretion and sex steroid concentrations in adult spotted hyenas, Crocuta crocuta.
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Efficacy of enzalutamide in subgroups of men with metastatic hormone-sensitive prostate cancer based on prior therapy, disease volume, and risk.
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Efficacy of peripheral androgen blockade in prostate cancer patients with biochemical failure after definitive local therapy: results of Cancer and Leukemia Group B (CALGB) 9782.
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Endocrine modulation of reproduction.
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Endocrine therapy in metastatic breast cancer.
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Enzalutamide Versus Bicalutamide in Castration-Resistant Prostate Cancer: The STRIVE Trial.
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Enzalutamide versus abiraterone acetate for the treatment of men with metastatic castration-resistant prostate cancer.
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Enzalutamide versus bicalutamide in patients with nonmetastatic castration-resistant prostate cancer: a prespecified subgroup analysis of the STRIVE trial.
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Enzalutamide with androgen deprivation therapy in Japanese men with metastatic hormone-sensitive prostate cancer: A subgroup analysis of the phase III ARCHES study.
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Evaluation and treatment of male and female pattern hair loss.
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Evidence Synthesis to Accelerate and Improve the Evaluation of Therapies for Metastatic Hormone-sensitive Prostate Cancer.
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Exercise as treatment for androgen deprivation therapy-associated physical dysfunction: ready for prime time?
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Exposure to naturally circulating androgens during foetal life incurs direct reproductive costs in female spotted hyenas, but is prerequisite for male mating.
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External beam radiation therapy for clinically localized prostate cancer: when and how we optimize with concurrent hormonal deprivation.
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Female Pattern Hair Loss and Androgen Excess: A Report From the Multidisciplinary Androgen Excess and PCOS Committee.
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First-year weight loss with androgen-deprivation therapy increases risks of prostate cancer progression and prostate cancer-specific mortality: results from SEARCH.
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Functional domain and motif analyses of androgen receptor coregulator ARA70 and its differential expression in prostate cancer.
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Hormonal therapy options for biochemical recurrence of prostate cancer after local therapy.
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Hormonal therapy options for prostate-specific antigen-only recurrence of prostate cancer after previous local therapy.
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Hormone refractory prostate cancer: Management and advances.
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Immunohistochemical characterization of neuroendocrine cells in prostate cancer.
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Immunologic and prognostic factors associated with overall survival employing a poxviral-based PSA vaccine in metastatic castrate-resistant prostate cancer.
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Impact of Late Dosing on Testosterone Suppression with 2 Different Leuprolide Acetate Formulations: In Situ Gel and Microsphere. An Analysis of United States Clinical Data.
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Impact of enzalutamide on patient-reported fatigue in patients with prostate cancer: data from the pivotal clinical trials.
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Impact of postoperative prostate-specific antigen disease recurrence and the use of salvage therapy on the risk of death.
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Impact of race on survival in men with metastatic hormone-refractory prostate cancer.
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Improved Survival With Enzalutamide in Patients With Metastatic Hormone-Sensitive Prostate Cancer.
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In hormone-naive metastatic prostate cancer, should all patients now receive docetaxel? No, not yet.
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Indications and practice with androgen deprivation therapy.
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Inhibition of androgen receptor-dependent transcriptional activity by DDT isomers and methoxychlor in HepG2 human hepatoma cells.
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Initial decline in hemoglobin during neoadjuvant hormonal therapy predicts for early prostate specific antigen failure following radiation and hormonal therapy for patients with intermediate and high-risk prostate cancer.
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Integrin involvement in freeze resistance of androgen-insensitive prostate cancer.
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Intermediate end point for prostate cancer-specific mortality following salvage hormonal therapy for prostate-specific antigen failure.
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Inverse correlation between body mass index and clinical outcomes in men with advanced castration-recurrent prostate cancer.
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Is NNT AOK?
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Is radical prostatectomy appropriate for very-high-risk prostate cancer patients? No.
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LINC00675 activates androgen receptor axis signaling pathway to promote castration-resistant prostate cancer progression.
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Leukemia Inhibitory Factor Promotes Castration-resistant Prostate Cancer and Neuroendocrine Differentiation by Activated ZBTB46.
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Ligand-specific dynamics of the androgen receptor at its response element in living cells.
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Loss of SPDEF and gain of TGFBI activity after androgen deprivation therapy promote EMT and bone metastasis of prostate cancer.
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MMTV-PyMT and Derived Met-1 Mouse Mammary Tumor Cells as Models for Studying the Role of the Androgen Receptor in Triple-Negative Breast Cancer Progression.
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Management of men with metastatic castration-resistant prostate cancer following potent androgen receptor inhibition: a review of novel investigational therapies.
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Management of patients with advanced prostate cancer: recommendations of the St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) 2015.
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Meerkat manners: Endocrine mediation of female dominance and reproductive control in a cooperative breeder.
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Metabolomic effects of androgen deprivation therapy treatment for prostate cancer.
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Metastatic Hormone-Sensitive Prostate Cancer: A Review of the Current Treatment Landscape.
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Molecular implications of the antiandrogen withdrawal syndrome.
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Multi-institutional Evaluation of Elective Nodal Irradiation and/or Androgen Deprivation Therapy with Postprostatectomy Salvage Radiotherapy for Prostate Cancer.
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Multicenter phase 2 study of neoadjuvant paclitaxel, estramustine phosphate, and carboplatin plus androgen deprivation before radiation therapy in patients with unfavorable-risk localized prostate cancer: results of Cancer and Leukemia Group B 99811.
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NCCN clinical practice guidelines in oncology: prostate cancer.
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Natural killer cell mobilization and egress following acute exercise in men with prostate cancer.
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Neoadjuvant androgen-deprivation therapy prior to radical prostatectomy: con.
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Neoadjuvant hormone therapy: the Canadian trials.
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Nerve growth factor interacts with CHRM4 and promotes neuroendocrine differentiation of prostate cancer and castration resistance.
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New drug development in metastatic prostate cancer.
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New drugs in prostate cancer.
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Niraparib in patients with metastatic castration-resistant prostate cancer and DNA repair gene defects (GALAHAD): a multicentre, open-label, phase 2 trial.
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Nivolumab plus rucaparib for metastatic castration-resistant prostate cancer: results from the phase 2 CheckMate 9KD trial.
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North American clinical management guidelines for hidradenitis suppurativa: A publication from the United States and Canadian Hidradenitis Suppurativa Foundations: Part II: Topical, intralesional, and systemic medical management.
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Novel chemotherapies in development for management of castration-resistant prostate cancer.
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Novel therapies for the treatment of advanced prostate cancer.
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Optimizing the use of docetaxel in men with castration-resistant metastatic prostate cancer.
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Overview consensus statement. Newer approaches to androgen deprivation therapy in prostate cancer.
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Phase 3 Randomized Controlled Trial of Androgen Deprivation Therapy with or Without Docetaxel in High-risk Biochemically Recurrent Prostate Cancer After Surgery (TAX3503).
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Phase II Trial of Enzalutamide and Androgen Deprivation Therapy with Salvage Radiation in Men with High-risk Prostate-specific Antigen Recurrent Prostate Cancer: The STREAM Trial.
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Phase II study of azacitidine to restore responsiveness of prostate cancer to hormonal therapy.
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Phase II study of cilengitide (EMD 121974, NSC 707544) in patients with non-metastatic castration resistant prostate cancer, NCI-6735. A study by the DOD/PCF prostate cancer clinical trials consortium.
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Phase II trial of bicalutamide in patients with androgen receptor-positive, estrogen receptor-negative metastatic Breast Cancer.
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Phase II trial of sunitinib for the therapy of progressive metastatic castration-refractory prostate cancer after previous docetaxel chemotherapy.
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Postoperative Radiation Therapy for Prostate Cancer: Comparison of Conventional Versus Hypofractionated Radiation Regimens.
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Pre-existing Castration-resistant Prostate Cancer-like Cells in Primary Prostate Cancer Promote Resistance to Hormonal Therapy.
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Predicting prostate cancer mortality among men with intermediate to high-risk disease and multiple unfavorable risk factors.
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Prognostic model for predicting survival in men with hormone-refractory metastatic prostate cancer.
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Prospective Evaluation of Clinical Outcomes Using a Multiplex Liquid Biopsy Targeting Diverse Resistance Mechanisms in Metastatic Prostate Cancer.
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Prostate Radiotherapy With Adjuvant Androgen Deprivation Therapy (ADT) Improves Metastasis-Free Survival Compared to Neoadjuvant ADT: An Individual Patient Meta-Analysis.
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Prostate cancer in the late 1990s: hormone refractory disease options.
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Prostate cancer, Version 3.2012: featured updates to the NCCN guidelines.
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Prostate cancer.
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Prostate cancer: molecular and cellular mechanisms and their implications in therapy resistance and disease progression.
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Prostate specific antigen recurrence after definitive therapy.
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Prostate tumor-derived GDF11 accelerates androgen deprivation therapy-induced sarcopenia.
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Prostate-specific antigen changes as surrogate for overall survival in men with metastatic castration-resistant prostate cancer treated with second-line chemotherapy.
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Prostate-specific antigen dynamics predict individual responses to intermittent androgen deprivation.
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Prostate-specific antigen nadir and cancer-specific mortality following hormonal therapy for prostate-specific antigen failure.
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Prostatic malignancy.
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Pyruvate kinase L/R links metabolism dysfunction to neuroendocrine differentiation of prostate cancer by ZBTB10 deficiency.
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Quality of life associated with treatment of castration-resistant prostate cancer: a review of the literature.
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Quality of life following localized prostate cancer treated initially with androgen deprivation therapy or no therapy.
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Racial Disparity in Response to Prostate Cancer Systemic Therapies.
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Randomized controlled trial of early zoledronic acid in men with castration-sensitive prostate cancer and bone metastases: results of CALGB 90202 (alliance).
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Randomized, double-blind, placebo-controlled phase III trial comparing docetaxel and prednisone with or without bevacizumab in men with metastatic castration-resistant prostate cancer: CALGB 90401.
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Regulation of the macrophage population in postnatal rat testis.
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Relative effectiveness and cost-effectiveness of methods of androgen suppression in the treatment of advanced prostate cancer.
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Resistance exercise training in patients with genitourinary cancers to mitigate treatment-related skeletal muscle loss.
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Response to bipolar androgen therapy and PD-1 inhibition in a patient with metastatic castration-resistant prostate cancer and a germline CHEK2 mutation.
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Rising prostate-specific antigen after primary prostate cancer therapy.
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Salvage radiation in men after prostate-specific antigen failure and the risk of death.
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Second-line chemotherapy for advanced hormone-refractory prostate cancer.
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Serum Lipids prior to Starting Androgen Deprivation Therapy and Risk of Castration Resistant Prostate Cancer and Metastasis: Results from the SEARCH Database.
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Short-course androgen ablation combined with external-beam radiation therapy and low-dose-rate permanent brachytherapy in early-stage prostate cancer: a matched subset analysis.
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Single-therapy androgen suppression in men with advanced prostate cancer: a systematic review and meta-analysis.
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Steroidal modulation of steroid secretion in vitro: an experimental approach to intra-follicular regulatory mechanisms.
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Stroke and thromboembolic events in men with prostate cancer treated with definitive radiation therapy with or without androgen deprivation therapy.
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Study Design and Rationale for the Phase 3 Clinical Development Program of Enobosarm, a Selective Androgen Receptor Modulator, for the Prevention and Treatment of Muscle Wasting in Cancer Patients (POWER Trials).
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Surgical management of high-risk, localized prostate cancer.
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Systematic review and meta-analysis of monotherapy compared with combined androgen blockade for patients with advanced prostate carcinoma.
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Testosterone in prostate cancer: the Bethesda consensus.
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The 1999 patterns of care study of radiotherapy in localized prostate carcinoma: a comprehensive survey of prostate brachytherapy in the United States.
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The STAMPEDE trial and celecoxib: how to adapt?
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The anti-androgen combination, flutamide plus finasteride, paradoxically suppressed LH and androgen concentrations in pregnant spotted hyenas, but not in males.
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The effect of prior androgen synthesis inhibition on outcomes of subsequent therapy with docetaxel in patients with metastatic castrate-resistant prostate cancer: results from a retrospective analysis of a randomized phase 3 clinical trial (CALGB 90401) (Alliance).
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The evolving landscape of metastatic hormone-sensitive prostate cancer: a critical review of the evidence for adding docetaxel or abiraterone to androgen deprivation.
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The impact of enzalutamide on quality of life in men with metastatic hormone-sensitive prostate cancer based on prior therapy, risk, and symptom subgroups.
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The impact of pathologic staging on the long-term oncologic outcomes of patients with clinically high-risk prostate cancer.
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The impact of prior radical prostatectomy in men with metastatic castration recurrent prostate cancer: a pooled analysis of 9 Cancer and Leukemia Group B Trials.
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The importance of dual 5alpha-reductase inhibition in the treatment of male pattern hair loss: results of a randomized placebo-controlled study of dutasteride versus finasteride.
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The influence of low-carbohydrate diets on the metabolic response to androgen-deprivation therapy in prostate cancer.
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The number of high-risk factors and the risk of prostate cancer-specific mortality after brachytherapy: implications for treatment selection.
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The role of androgen deprivation therapy combined with prostate brachytherapy.
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The type of ADT may matter for testosterone recovery.
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The urology perspective on expanding androgen-targeted treatments for men with castration-resistant prostate cancer.
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Timing of androgen deprivation therapy and its impact on survival after radical prostatectomy: a matched cohort study.
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Traditional approaches to androgen deprivation therapy.
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Treating the biochemical recurrence of prostate cancer after definitive primary therapy.
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Triplet Therapy: Entering the Metaverse of Metastatic Hormone-sensitive Prostate Cancer Treatment.
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Tumor volume changes on 1.5 tesla endorectal MRI during neoadjuvant androgen suppression therapy for higher-risk prostate cancer and recurrence in men treated using radiation therapy results of the phase II CALGB 9682 study.
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Twenty years of controversy surrounding combined androgen blockade for advanced prostate cancer.
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Update on metastatic hormone-sensitive prostate cancer.
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Utilization of a Genomic Classifier for Prediction of Metastasis Following Salvage Radiation Therapy after Radical Prostatectomy.
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What Experts Think About Prostate Cancer Management During the COVID-19 Pandemic: Report from the Advanced Prostate Cancer Consensus Conference 2021.