Anesthetics, Local

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  Subject Areas on Research

  • A Method for Cranial Nerve XI Silencing During Surgery of the Foramen Magnum Region: Technical Case Report. 
  • A comparative evaluation of intrapleural and thoracic epidural analgesia for postoperative pain relief after minimally invasive direct coronary artery bypass surgery. 
  • A comparison of 0.5% bupivacaine, 0.5% ropivacaine, and 0.75% ropivacaine for interscalene brachial plexus block. 
  • A comparison of rocuronium and lidocaine for the prevention of postoperative myalgia after succinylcholine administration. 
  • A disinhibitory circuit mediates motor integration in the somatosensory cortex. 
  • A double-masked randomized trial of postoperative local anesthetic for pain control in pediatric strabismus surgery. 
  • A moldable sustained release bupivacaine formulation for tailored treatment of postoperative dental pain. 
  • A novel paraplegia model in awake behaving macaques. 
  • A retrospective comparison of programmed intermittent epidural bolus with continuous epidural infusion for maintenance of labor analgesia. 
  • A voltage-gated calcium-selective channel encoded by a sodium channel-like gene. 
  • Accuracy of glenohumeral joint injections: comparing approach and experience of provider. 
  • Activity-dependent PSA expression regulates inhibitory maturation and onset of critical period plasticity. 
  • Acute renal failure and pigmentation due to phenazopyridine (Pyridium). 
  • Acute upper airway angioedema secondary to acquired C1 esterase inhibitor deficiency: a case report. 
  • Addition of epinephrine to epidural bupivacaine infusions following initiation of labor analgesia with epidural fentanyl. 
  • Ambulatory continuous perineural infusion: are we ready? 
  • Ambulatory continuous peripheral nerve blocks to treat postamputation phantom limb pain: a multicenter, randomized, quadruple-masked, placebo-controlled clinical trial. 
  • Ambulatory discharge after long-acting peripheral nerve blockade: 2382 blocks with ropivacaine. 
  • American College of Chest Physicians consensus statement on the use of topical anesthesia, analgesia, and sedation during flexible bronchoscopy in adult patients. 
  • Analgesia in the surgical intensive care unit. 
  • Analgesic Effects of a Novel Combination of Regional Anesthesia After Pediatric Cardiac Surgery: A Retrospective Cohort Study. 
  • Analysis of the action of lidocaine on insect sodium channels. 
  • Anesthetic management of a patient having a carcinoid syndrome. 
  • Anxiety, vocalization, and agitation following peripheral nerve block with ropivacaine. 
  • Application of continuous incisional infusion of local anesthetic after major pediatric urological surgery. 
  • Application of continuous incisional infusion of local anesthetic after major pediatric urological surgery: prospective randomized controlled trial. 
  • Assessment of postoperative analgesia after application of ultrasound-guided regional anesthesia for surgery in a swine femoral fracture model. 
  • Autonomic Modulation for the Treatment of Ventricular Arrhythmias: Therapeutic Use of Percutaneous Stellate Ganglion Blocks. 
  • Benzyl alcohol protects against acetaminophen hepatotoxicity by inhibiting cytochrome P450 enzymes but causes mitochondrial dysfunction and cell death at higher doses. 
  • Brachial Plexus Block with Liposomal Bupivacaine for Shoulder Surgery Improves Analgesia and Reduces Opioid Consumption: Results from a Multicenter, Randomized, Double-Blind, Controlled Trial. 
  • Breast lidocaine priming for improved mastectomy survival. 
  • Brief report: a randomized controlled trial of Synera versus lidocaine for epidural needle insertion in labouring parturients. 
  • CT-guided lumbar nerve root injections: are we using the correct radiation dose settings? 
  • Case reports: two cases of glenohumeral chondrolysis after intraarticular pain pumps. 
  • Central nervous system toxicity following the administration of levobupivacaine for lumbar plexus block: A report of two cases. 
  • Cervical sympathetic block to reverse delayed ischemic neurological deficits after aneurysmal subarachnoid hemorrhage. 
  • Combined general-epidural anesthesia decreases the desflurane requirement for equivalent A-line ARX index in colorectal surgery. 
  • Combined lipid emulsion and ACLS resuscitation following bupivacaine- and hypoxia-induced cardiovascular collapse in unanesthetized swine. 
  • Combined lumbar-plexus and sciatic-nerve blocks: an analysis of plasma ropivacaine concentrations. 
  • Comparison of Programmed Intermittent Epidural Boluses With Continuous Epidural Infusion for the Maintenance of Labor Analgesia: A Randomized, Controlled, Double-Blind Study. 
  • Comparison of local anesthetic infusion pump bupivacaine versus transversus abdominis plane (TAP) block liposomal bupivacaine for pain management after bilateral deep inferior epigastric perforator free flap reconstruction. 
  • Continuous adductor canal blockade facilitates increased home discharge and decreased opioid consumption after total knee arthroplasty. 
  • Continuous peripheral nerve block for ambulatory surgery. 
  • Contralateral local anesthetic spread from an outpatient interscalene catheter. 
  • Diabetes mellitus, independent of body mass index, is associated with a "higher success" rate for supraclavicular brachial plexus blocks. 
  • Does a positive response to spermatic cord block predict response to microdenervation of the spermatic cord for chronic scrotal content pain? 
  • Dural ectasia: a likely cause of inadequate spinal anaesthesia in two parturients with Marfan's syndrome. 
  • ED 90 of Intrathecal Chloroprocaine With Fentanyl for Prophylactic Cervical Cerclage: A Sequential Allocation Biased-Coin Design. 
  • Editorial Commentary: Postoperative Pain Management After Anterior Cruciate Ligament Reconstruction Can Minimize Opioid Use and Allow Early Rehabilitation. 
  • Effect of cocaine and cocaine congeners on veratridine-induced depolarization in mouse cerebrocortical synaptoneurosomes. 
  • Effect of intravenous lidocaine on the transcerebral inflammatory response during cardiac surgery: a randomized-controlled trial. 
  • Effect of lidocaine gel anesthesia on endophthalmitis rates following intravitreal injection. 
  • Effect of lidocaine on endothelin-1-mediated airway smooth muscle contraction in the rat trachea. 
  • Effective local anesthesia for onabotulinumtoxin A injections to treat hyperhidrosis associated with traumatic amputation. 
  • Effects of local anesthetics on guanyl nucleotide modulation of the catecholamine-sensitive adenylate cyclase system and on beta-adrenergic receptors. 
  • Efficacy of intravesical ropivacaine injection on urinary symptoms following ureteral stenting: a randomized, controlled study. 
  • Efficacy of single-dose, multilevel paravertebral nerve blockade for analgesia after thoracoscopic procedures. 
  • Electromyographic assessment of ulnar nerve motor block induced by lidocaine. 
  • Elevated lidocaine serum concentration after subcutaneous lidocaine administration using a needle-free device in pediatric patients. 
  • Elevated lidocaine serum levels following the use of a needle free device in healthy adult volunteers. 
  • Endotracheal lidocaine administration via an esophageal combitube. 
  • Essentials of Our Current Understanding: Abdominal Wall Blocks. 
  • Evaluation of a new cutaneous topical anesthesia preparation. 
  • Evaluation of trends in continuous peripheral nerve block utilization for total knee arthroplasty within and outside the Veterans Affairs Healthcare System. 
  • Exparel for Postoperative Pain Management: a Comprehensive Review. 
  • Factors affecting pain scores during female urethral catheterization. 
  • Fascia Iliaca Blockade With the Addition of Liposomal Bupivacaine Versus Plain Bupivacaine for Perioperative Pain Management During Hip Arthroscopy: A Double-Blinded Prospective Randomized Control Trial. 
  • Fascia iliaca blockade with the addition of liposomal bupivacaine vs. plain bupivacaine for perioperative pain management following hip arthroscopy. 
  • Femoral artery block (FAB) attenuates thigh tourniquet-induced hypertension: a prospective randomized, double-blind, placebo-controlled trial. 
  • Fiberoptic intubation. 
  • Grand mal seizure during cardiopulmonary bypass: probable lidocaine toxicity. 
  • High spinal anesthesia for cardiac surgery: effects on beta-adrenergic receptor function, stress response, and hemodynamics. 
  • High-dose versus low-dose local anaesthetic for transversus abdominis plane block post-Caesarean delivery analgesia: a meta-analysis. 
  • Histopathology after lidocaine/prilocaine cream administration for vulvar biopsy. 
  • How central is central poststroke pain? The role of afferent input in poststroke neuropathic pain: a prospective, open-label pilot study. 
  • Images in Anesthesiology: Ultrasound-guided Intraarticular Knee Injection. 
  • Immediate Effects of a Continuous Peripheral Nerve Block on Postamputation Phantom and Residual Limb Pain: Secondary Outcomes From a Multicenter Randomized Controlled Clinical Trial. 
  • Impact of Sodium Bicarbonate-Buffered Lidocaine on Patient Pain During Image-Guided Breast Biopsy. 
  • Impact of liposomal bupivacaine administration on postoperative pain in patients undergoing total knee replacement. 
  • In vitro evaluation of diffusion of lidocaine and alkalinized lidocaine through the polyurethane membrane of the endotracheal tube. 
  • In vivo diffusion-weighted magnetic resonance microscopy of rat spinal cord: effect of ischemia and intrathecal hyperbaric 5% lidocaine. 
  • Inferior oblique overaction/contracture following retrobulbar anesthesia for cataract extraction with a positive Bielschowsky Head Tilt test to the contralateral shoulder. A report of one case. 
  • Inhibition of mechanical allodynia in neuropathic pain by TLR5-mediated A-fiber blockade. 
  • Interaction of anaesthetics with electrical synapses. 
  • Intermittent epidural bolus compared with continuous epidural infusions for labor analgesia: a systematic review and meta-analysis. 
  • Interscalene block with liposomal bupivacaine versus continuous interscalene catheter in primary total shoulder arthroplasty. 
  • Interscalene brachial plexus block with a continuous catheter insertion system and a disposable infusion pump. 
  • Interscalene brachial plexus block with continuous intraarticular infusion of ropivacaine. 
  • Intra-arterial chloroprocaine for the control of pain associated with partial splenic embolization. 
  • Intraarticular analgesia in shoulder surgery. 
  • Intracameral anesthesia: in vitro iris and corneal uptake and washout of 1% lidocaine hydrochloride. 
  • Intraneural injection and peripheral nerve injury. 
  • Intraoperative Electromyography in Awake Minimally Invasive Transforaminal Lumbar Interbody Fusion: A Case Study on Nerve Activation Under the Effects of Local Anesthesia. 
  • Intraoperative bupivacaine for reduction of post-tonsillectomy pain: a randomized, placebo-controlled, double-blind study of 26 patients. 
  • Intraperitoneal and intravenous routes for pain relief in laparoscopic cholecystectomy. 
  • Intrathecal bupivacaine versus chloroprocaine for transvaginal cervical cerclage placement: a retrospective cohort study. 
  • Intrathecal sufentanil for extracorporeal shock wave lithotripsy provides earlier discharge of the outpatient than intrathecal lidocaine. 
  • Intrauterine anesthesia for gynecologic procedures: a systematic review. 
  • Intravenous Lidocaine Does Not Improve Neurologic Outcomes after Cardiac Surgery: A Randomized Controlled Trial. 
  • Intravenous Lidocaine and Postoperative Cognition: Reply. 
  • Intravenous Migraine Treatment in Children and Adolescents. 
  • Laparo-endoscopic single-site (LESS) cholecystectomy with epidural vs. general anesthesia. 
  • Laser Doppler flowmetry: a clinical test of pulpal vitality. 
  • Lefetamine: new abuse of an old drug--clinical evaluation of opioid activity. 
  • Levobupivacaine versus racemic bupivacaine for extradural anesthesia for cesarean delivery. 
  • Lidocaine Infusion as an Adjunct to Narcotics in Trauma Patients with Rib Fractures-A Pilot Study. 
  • Lidocaine lollipop as single-agent anesthesia in upper GI endoscopy. 
  • Lidocaine lollipop for awake fiberoptic bronchoscopy. 
  • Lidocaine patch for acute pain management: a meta-analysis of prospective controlled trials. 
  • Lidocaine patch for postoperative analgesia after radical retropubic prostatectomy. 
  • Lidocaine-Prilocaine Cream Compared With Injected Lidocaine for Vulvar Biopsy: A Randomized Controlled Trial. 
  • Lipid solubility modulates pH potentiation of local anesthetic block of Vmax reactivation in guinea pig myocardium. 
  • Liposomal bupivacaine in forefoot surgery. 
  • Local anaesthetic wound infiltration for postcaesarean section analgesia: A systematic review and meta-analysis. 
  • Local anesthetic activity and acute toxicity of N-heptyl-1,2,3,4-tetrahydro-6-methoxy-1-naphthylamine methanesulfonate. 
  • Local anesthetic activity and acute toxicity of N-substituted 1,2,3,4-tetrahydro-1- and 2-naphthylamines. 
  • Local anesthetics and mode of delivery: bupivacaine versus ropivacaine versus levobupivacaine. 
  • Local anesthetics, neuraxial anesthesia, and the Brugada syndrome. 
  • Long-term results of Ingelman-Sundberg denervation procedure for urge incontinence refractory to medical therapy. 
  • Low interscalene block provides reliable anesthesia for surgery at or about the elbow. 
  • Lumbar plexus and sciatic nerve block for knee arthroplasty: comparison of ropivacaine and bupivacaine. 
  • Mechanisms of use-dependent block of sodium channels in excitable membranes by local anesthetics. 
  • Membrane action of DMSO and other chemical inducers of Friend leukaemic cell differentiation. 
  • Methemoglobinemia complicating topical anesthesia during bronchoscopic procedures. 
  • Methemoglobinemia with the use of benzocaine spray for awake fiberoptic intubation. 
  • Minimum effective dose of spinal ropivacaine with and without fentanyl for postpartum tubal ligation. 
  • Monitoring during peripheral nerve blockade. 
  • Motor blocking minimum local anesthetic concentrations of bupivacaine, levobupivacaine, and ropivacaine in labor. 
  • Multidisciplinary simulation of local anaesthetic systemic toxicity improves diagnostic and treatment skills and self-confidence for pain clinic procedural staff. 
  • Mutations in the transmembrane helix S6 of domain IV confer cockroach sodium channel resistance to sodium channel blocker insecticides and local anesthetics. 
  • Nasal tetracaine spray-induced methemoglobinemia. 
  • Nerve conduction blockade in the sciatic nerve prevents but does not reverse the activation of p38 mitogen-activated protein kinase in spinal microglia in the rat spared nerve injury model. 
  • Organization of the intermediate gray layer of the superior colliculus. I. Intrinsic vertical connections. 
  • Paediatric regional anaesthesia--what makes a difference? 
  • Pain perception with cervical tenaculum placement during intrauterine device insertion: a randomised controlled trial. 
  • Paravertebral block anesthesia for inguinal hernia repair. 
  • Partial Wrist Denervation: The Evidence Behind a Small Fix for Big Problems. 
  • Pectoral Fascial (PECS) I and II Blocks as Rescue Analgesia in a Patient Undergoing Minimally Invasive Cardiac Surgery. 
  • Periarticular Injections in Knee and Hip Arthroplasty: Where and What to Inject. 
  • Perioperative Management in Shoulder Arthroplasty: A Review of Current Practice. 
  • Peripheral nerve blockade with long-acting local anesthetics: a survey of the Society for Ambulatory Anesthesia. 
  • Pharmacokinetics and Tolerability of Intraperitoneal Chloroprocaine After Fetal Extraction in Women Undergoing Cesarean Delivery. 
  • Plasticity of both excitatory and inhibitory synapses is associated with seizures induced by removal of chronic blockade of activity in cultured hippocampus. 
  • Population pharmacokinetics of lidocaine administered during and after cardiac surgery. 
  • Posterior capsular injections of ropivacaine during total knee arthroplasty: a randomized, double-blind, placebo-controlled study. 
  • Posterior lingual lidocaine: a novel method to improve tolerance in upper gastrointestinal endoscopy. 
  • Preventing pain during office biopsy of the prostate: a single center, prospective, double-blind, 3-arm, parallel group, randomized clinical trial. 
  • Prospective, Randomized, Controlled Comparison of Bupivacaine versus Liposomal Bupivacaine for Pain Management after Unilateral Delayed Deep Inferior Epigastric Perforator Free Flap Reconstruction. 
  • Pump activated by a foot switch pedal for controlled administration of local anaesthetic drugs. 
  • Pump activated by a foot switch pedal for controlled administration of local anaesthetic drugs. 
  • Quality of Labor Analgesia with Dural Puncture Epidural versus Standard Epidural Technique in Obese Parturients: A Double-blind Randomized Controlled Study. 
  • Randomized Controlled Trial to Assess the Impact of High Concentration Intraurethral Lidocaine on Urodynamic Voiding Parameters. 
  • Randomized Controlled Trial to Assess the Impact of Intraurethral Lidocaine on Urodynamic Voiding Parameters. 
  • Randomized controlled trial investigating the effect of transcervical papaverine and bupivacaine on postoperative analgesia following laparoscopic sterilization. 
  • Randomized trial of transversus abdominis plane block with liposomal bupivacaine after cesarean delivery with or without intrathecal morphine. 
  • Randomized, double-blinded, placebo controlled study of neuroprotection with lidocaine in cardiac surgery. 
  • Re: Inferior oblique overaction/contracture following retrobulbar anesthesia for cataract extraction with a positive Bielschowsky Head Tilt Test to the contralateral shoulder. A report of one case. 
  • Recommendations for the pharmacological management of neuropathic pain: an overview and literature update. 
  • Recurrence of local anesthetic cardiac toxicity or hypokalemia? 
  • Recurrent interactions between the input and output of a songbird cortico-basal ganglia pathway are implicated in vocal sequence variability. 
  • Reply to 'Successful resuscitation of bupivacaine-induced cardiotoxicity in a neonate'. 
  • Reply to Drs Egeler, Jayakumar, and Ford. 
  • Reply. 
  • Response to "Intraurethral Lidocaine Use During Urodynamic Testing Deserves Further Study". 
  • Retinal Degeneration After Accidental Intravitreal Injection of Ropivacaine During Strabismus Surgery. 
  • Reversible inactivation of macaque dorsomedial frontal cortex: effects on saccades and fixations. 
  • Reversible inactivation of macaque frontal eye field. 
  • Role of pudendal afferents in voiding efficiency in the rat 
  • Ropivacaine and Ketorolac Wound Infusion for Post-Cesarean Delivery Analgesia: A Randomized Controlled Trial. 
  • Saphenous Nerve Block From Within the Knee Is Feasible for TKA: MRI and Cadaveric Study. 
  • Severe phantom leg pain in an amputee after lumbar plexus block. 
  • Small-dose intrathecal lidocaine versus ropivacaine for anorectal surgery in an ambulatory setting. 
  • Sonographic evaluation of lumbar interlaminar space opening in a variety of patient body positions for optimal neuraxial anesthesia delivery. 
  • Spinal anesthesia for postpartum tubal ligation: A retrospective analysis of the association of intrathecal bupivacaine dosing with inadequate surgical blocks. 
  • Strong single-fiber sensory inputs to olfactory cortex: implications for olfactory coding. 
  • Subarachnoid meperidine (Pethidine) causes significant nausea and vomiting during labor. The Duke Women's Anesthesia Research Group. 
  • Subcutaneous bupivacaine infiltration and postoperative pain perception after percutaneous nephrolithotomy. 
  • Subpleural block is less effective than thoracic epidural analgesia for post-thoracotomy pain: a randomised controlled study. 
  • Subtle desaturation and perioperative methemoglobinemia. The need for continued vigilance. 
  • Successful resuscitation after ropivacaine-induced ventricular fibrillation. 
  • Surgeon-Performed High-Dose Bupivacaine Periarticular Injection With Intra-Articular Saphenous Nerve Block Is Not Inferior to Adductor Canal Block in Total Knee Arthroplasty. 
  • Synaptic basis for developmental plasticity in a birdsong nucleus. 
  • The "Step-Off" Technique Can Confirm a Successful Peripheral Nerve Block. 
  • The Retroclavicular Brachial Plexus Block: Additional Advantages. 
  • The Use of Liposomal Bupivacaine Administered With Standard Bupivacaine in Ankle Fractures Requiring Open Reduction Internal Fixation: A Single-Blinded Randomized Controlled Trial. 
  • The difficulties of ambulatory interscalene and intra-articular infusions for rotator cuff surgery: a preliminary report. 
  • The effect of age on sciatic nerve block duration. 
  • The effect of mixing 1.5% mepivacaine and 0.5% bupivacaine on duration of analgesia and latency of block onset in ultrasound-guided interscalene block. 
  • The effect of repeated measurements and the use of topical anesthetic on rebound tonometry values in children. 
  • The effect of stimulating versus conventional perineural catheters on postoperative analgesia following ultrasound-guided femoral nerve localization. 
  • The effects of intraocular lidocaine on the corneal endothelium. 
  • The effects of ultrasound-guided adductor canal block versus femoral nerve block on quadriceps strength and fall risk: a blinded, randomized trial of volunteers. 
  • The interaction effect of perioperative cotreatment with dextromethorphan and intravenous lidocaine on pain relief and recovery of bowel function after laparoscopic cholecystectomy. 
  • The need for caution with topical anesthesia during endoscopic procedures, as liberal use may result in methemoglobinemia. 
  • The relative analgesic value of a femoral nerve block versus adductor canal block following total knee arthroplasty: a randomized, controlled, double-blinded study. 
  • The use of topical anesthesia during intravenous catheter insertion in adults: a comparison of pain scores using LMX-4 versus placebo. 
  • The value of the P-value. 
  • Topical anesthesia with EMLA reduces pain during endomyocardial biopsy: a randomized trial. 
  • Toxin injury-dependent switched expression between EF-1 alpha and its sister, S1, in rat skeletal muscle. 
  • Transversus Abdominis Plane Block With Liposomal Bupivacaine for Pain After Cesarean Delivery in a Multicenter, Randomized, Double-Blind, Controlled Trial. 
  • Treatment considerations for elderly and frail patients with neuropathic pain. 
  • Treatment of decompression illness and latrogenic gas embolism. 
  • Treatment of dopplerable nummular headache with minimally invasive arterectomy under local anesthesia. 
  • Trends in spinal pain management injections in academic radiology departments. 
  • Ultrasonography and pediatric caudals. 
  • Ultrasound-guided genicular nerve blocks following total knee arthroplasty: a randomized, double-blind, placebo-controlled trial. 
  • Urethral afferent nerve activity affects the micturition reflex; implication for the relationship between stress incontinence and detrusor instability. 
  • Use of a simple forearm tourniquet as an adjunct to an intravenous regional block. 
  • Use of bulleyaconitine A as an adjuvant for prolonged cutaneous analgesia in the rat. 
  • Use of local anesthetic a key tenet in multimodal analgesia to modulate chronic post-mastectomy pain. 
  • Use of targeted transversus abdominus plane blocks in pediatric patients with anterior cutaneous nerve entrapment syndrome. 
  • ☆Diagnostic and therapeutic injections of the foot and ankle-An overview. 
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  Keywords of People

  • Laskowitz, Daniel Todd, Professor of Neurology, Duke Science & Society
  • Routh, Jonathan Charles, Paul H. Sherman, M.D. Distinguished Associate Professor of Surgery, Pediatrics