Angiotensinogen

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  Subject Areas on Research

  • A comparative study of the distributions of renin and angiotensinogen messenger ribonucleic acids in rat and mouse tissues. 
  • Altered sodium regulation of renal angiotensinogen mRNA in the spontaneously hypertensive rat. 
  • Analysis of the plasma elimination kinetics and conformational stabilities of native, proteinase-complexed, and reactive site cleaved serpins: comparison of alpha 1-proteinase inhibitor, alpha 1-antichymotrypsin, antithrombin III, alpha 2-antiplasmin, angiotensinogen, and ovalbumin. 
  • Androgen regulation of rat renal angiotensinogen messenger RNA expression. 
  • Angiotensinogen gene null-mutant mice lack homeostatic regulation of glomerular filtration and tubular reabsorption. 
  • Angiotensinogen genotype and blood pressure response in the Dietary Approaches to Stop Hypertension (DASH) study. 
  • Angiotensinogen synthesis in the liver is independent of physiological estrogen levels. 
  • Association of angiotensinogen gene T235 variant with increased risk of coronary heart disease. 
  • CRISPR/Cas9 Mediated Deletion of the Angiotensinogen Gene Reduces Hypertension: A Potential for Cure? 
  • Characterization of a putative insulin-responsive element and its binding protein(s) in rat angiotensinogen gene promoter: regulation by glucose and insulin. 
  • Classical Renin-Angiotensin system in kidney physiology. 
  • Differential effects of captopril and enalapril on tissue renin-angiotensin systems in experimental heart failure. 
  • Effect of renin-angiotensin system blockade on the expression of the angiotensinogen gene and induction of hypertrophy in rat kidney proximal tubular cells. 
  • Essential role(s) of the intrarenal renin-angiotensin system in transforming growth factor-beta1 gene expression and induction of hypertrophy of rat kidney proximal tubular cells in high glucose. 
  • Evidence for tissue-specific activation of renal angiotensinogen mRNA expression in chronic stable experimental heart failure. 
  • Expression of renin-angiotensin system and extracellular matrix genes in cardiovascular cells and its regulation through AT1 receptor. 
  • Gene expression of the renin-angiotensin system in human tissues. Quantitative analysis by the polymerase chain reaction. 
  • Gene targeting in mice reveals a requirement for angiotensin in the development and maintenance of kidney morphology and growth factor regulation. 
  • Gene-targeting studies of the renin-angiotensin system: mechanisms of hypertension and cardiovascular disease. 
  • Genetic control of blood pressure and the angiotensinogen locus. 
  • Genetic manipulation of the renin-angiotensin system. 
  • Granulocyte-angiotensin system. Identification of angiotensinogen as the plasma protein substrate of leukocyte cathepsin G. 
  • High glucose stimulates angiotensinogen gene expression and cell hypertrophy via activation of the hexosamine biosynthesis pathway in rat kidney proximal tubular cells. 
  • High glucose stimulates angiotensinogen gene expression via reactive oxygen species generation in rat kidney proximal tubular cells. 
  • High levels of glucose stimulate angiotensinogen gene expression via the P38 mitogen-activated protein kinase pathway in rat kidney proximal tubular cells. 
  • Hormonal control of angiotensinogen production. 
  • Hyperglycemia induces insulin resistance on angiotensinogen gene expression in diabetic rat kidney proximal tubular cells. 
  • Identification of renin and angiotensinogen messenger RNA sequences in mouse and rat brains. 
  • Immortalized rat proximal tubule cell lines expressing components of the renin-angiotensin system. 
  • In situ hybridization evidence for angiotensinogen messenger RNA in the rat proximal tubule. An hypothesis for the intrarenal renin angiotensin system. 
  • Insulin inhibits angiotensinogen gene expression via the mitogen-activated protein kinase pathway in rat kidney proximal tubular cells. 
  • Insulin inhibits dexamethasone effect on angiotensinogen gene expression and induction of hypertrophy in rat kidney proximal tubular cells in high glucose. 
  • Intrarenal angiotensinogen: localization and regulation. 
  • Is renin a factor in the etiology of essential hypertension? 
  • Localization and differential regulation of angiotensinogen mRNA expression in the vessel wall. 
  • Modulation of the BP response to diet by genes in the renin-angiotensin system and the adrenergic nervous system. 
  • Molecular and physiological aspects of tissue renin-angiotensin system: emphasis on cardiovascular control. 
  • Molecular biology and pathophysiology of the intrarenal renin-angiotensin system. 
  • Molecular mechanisms of glucose action on angiotensinogen gene expression in rat proximal tubular cells. 
  • Molecular mechanisms of vascular renin-angiotensin system in myointimal hyperplasia. 
  • Multiple pathways of angiotensin production in the blood vessel wall: evidence, possibilities and hypotheses. 
  • Quantitation of the five forms of plasma high molecular weight angiotensinogen in women with pregnancy-induced hypertension. 
  • Rat proximal tubule cell line transformed with origin-defective SV40 DNA: autocrine ANG II feedback. 
  • Reactive oxygen species blockade and action of insulin on expression of angiotensinogen gene in proximal tubular cells. 
  • Reciprocal feedback regulation of kidney angiotensinogen and renin mRNA expressions by angiotensin II. 
  • Reduced growth, abnormal kidney structure, and type 2 (AT2) angiotensin receptor-mediated blood pressure regulation in mice lacking both AT1A and AT1B receptors for angiotensin II. 
  • Regulation of intrarenal and circulating renin-angiotensin systems in severe heart failure in the rat. 
  • Regulation of tissue renin and angiotensin gene expressions. 
  • Renin and angiotensinogen mRNA expression in the kidneys of rats subjected to long-term bile duct ligation. 
  • Renin expression by vascular endothelial cells in culture. 
  • Sexual dimorphism of urine angiotensinogen excretion in the rat. 
  • Sodium regulation of angiotensinogen mRNA expression in rat kidney cortex and medulla. 
  • Special deLIVERy: podocyte injury promotes renal angiotensin II generation from liver-derived angiotensinogen. 
  • Targeting genes in the renin-angiotensin system. 
  • The feedback regulation of angiotensinogen production by components of the renin-angiotensin system. 
  • Urinary Angiotensinogen Could Be a Prognostic Marker of Renoprotective Effects of Alogliptin in Patients with Type 2 Diabetes. 
  • Variations of cardiovascular disease associated genes exhibit sex-dependent influence on human longevity. 
  • Vascular renin-angiotensin: a possible autocrine or paracrine system in control of vascular function. 
  • Vascular wall renin-angiotensin pathway in control of the circulation. A hypothesis. 
  • What can knockout mice contribute to an understanding of hypertension? 
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  Keywords of People

  • Hogan, Brigid L. M., Research Professor of Cell Biology, Cell Biology