Animal Testing Alternatives

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  Subject Areas on Research

  • A review of three-dimensional in vitro tissue models for drug discovery and transport studies. 
  • Advancing the science of developmental neurotoxicity (DNT): testing for better safety evaluation. 
  • Adverse outcome pathways during early fish development: a conceptual framework for identification of chemical screening and prioritization strategies. 
  • Caenorhabditis elegans generates biologically relevant levels of genotoxic metabolites from aflatoxin B1 but not benzo[a]pyrene in vivo 
  • Quality assurance of metabolomics. 
  • Reference compounds for alternative test methods to indicate developmental neurotoxicity (DNT) potential of chemicals: example lists and criteria for their selection and use. 
  • Systems biology for organotypic cell cultures. 
  • The cost of self-imposed regulatory burden in animal research. 
  • The fish embryo toxicity test as an animal alternative method in hazard and risk assessment and scientific research. 
  • Use of non-mammalian alternative models for neurotoxicological study. 
  • t⁴ workshop report. Nanotoxicology: "the end of the beginning" - signs on the roadmap to a strategy for assuring the safe application and use of nanomaterials.