Anti-Inflammatory Agents

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  Subject Areas on Research

  • "Low-level" carbon monoxide administration may carry risk. 
  • 2-O, 3-O-desulfated heparin inhibits neutrophil elastase-induced HMGB-1 secretion and airway inflammation. 
  • 2011 American College of Rheumatology recommendations for the treatment of juvenile idiopathic arthritis: initiation and safety monitoring of therapeutic agents for the treatment of arthritis and systemic features. 
  • A Case Report of Acute Cellular Rejection Following Intestinal Transplantation Managed With Adalimumab. 
  • A Multicenter Study of Early Anti-inflammatory Treatment in Patients With Acute Anterior Cruciate Ligament Tear. 
  • A childlike presentation? 
  • A cross sectional analysis of 5 different markers of collagen degradation in rheumatoid arthritis. 
  • A double-blind controlled comparison of generic and trade-name topical steroids using the vasoconstriction assay. 
  • A double-blind study comparing benoxaprofen, aspirin, and benoxaprofen plus aspirin in patients with rheumatoid arthritis. 
  • A genetically engineered thermally responsive sustained release curcumin depot to treat neuroinflammation. 
  • A new BEACON of hope for the treatment of inflammation? The endogenous metabolite itaconate as an alternative activator of the KEAP1-Nrf2 system. 
  • A novel therapeutic derived from apolipoprotein E reduces brain inflammation and improves outcome after closed head injury. 
  • A systematic review of morphea treatments and therapeutic algorithm. 
  • A whole animal chemical screen approach to identify modifiers of intestinal neutrophilic inflammation. 
  • ALSUntangled No. 26: lunasin. 
  • Aberrant tRNA processing causes an autoinflammatory syndrome responsive to TNF inhibitors. 
  • Actions of glucocorticosteroids on ischemic-reperfused muscle and cutaneous tissue. 
  • Acute eosinophilic pneumonia in a New York City firefighter exposed to World Trade Center dust. 
  • Acute upper airway angioedema secondary to acquired C1 esterase inhibitor deficiency: a case report. 
  • Adalimumab for prevention of uveitic flare in patients with inactive non-infectious uveitis controlled by corticosteroids (VISUAL II): a multicentre, double-masked, randomised, placebo-controlled phase 3 trial. 
  • Adalimumab for the treatment of psoriasis. 
  • Age-related differences in pulmonary cytokine response to respiratory syncytial virus infection: modulation by anti-inflammatory and antiviral treatment. 
  • Aggressive topical corticosteroid therapy: a novel approach to mast-cell-dependent cutaneous disorders. 
  • Alendronate tracheobronchitis. 
  • Allergic skin disorders. 
  • An unusual dienone-phenol rearrangement product formed during the synthesis of mometasone furoate (Sch 32088). 
  • An unusual rearrangement product formed during production of mometasone furoate (Sch 32088). 
  • Anti-inflammatory activity of amine cyanoboranes, amine carboxyboranes, and related compounds. 
  • Anti-inflammatory and Anti-HIV Compounds from Swertia bimaculata. 
  • Anti-inflammatory and vasoprotective activity of a retroviral-derived peptide, homologous to human endogenous retroviruses: endothelial cell effects. 
  • Anti-inflammatory effects of inhibiting the amine oxidase activity of semicarbazide-sensitive amine oxidase. 
  • Anti-inflammatory effects of progesterone in lipopolysaccharide-stimulated BV-2 microglia. 
  • Anti-inflammatory signaling during ex vivo liver perfusion improves the preservation of pig liver grafts before transplantation. 
  • Anti-inflammatory strategies and hemostatic agents: old drugs, new ideas. 
  • Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease. 
  • Antiinflammatory activity of substituted 6-hydroxypyrimido[2,1-f]purine-2,4,8(1H,3H,9H)-triones. Atypical nonsteroidal antiinflammatory agents. 
  • Antiinflammatory effects of neoplasms. 
  • Antiinflammatory, analgesic and antiperoxidative efficacy of Barleria lupulina Lindl. extract. 
  • Antithrombin: anti-inflammatory properties and clinical applications. 
  • Apolipoprotein E-derived peptides ameliorate clinical disability and inflammatory infiltrates into the spinal cord in a murine model of multiple sclerosis. 
  • Association of Disorganization of Retinal Inner Layers With Visual Acuity In Eyes With Uveitic Cystoid Macular Edema. 
  • BMS-229724 is a tight-binding inhibitor of cytosolic phospholipase A2 that acts at the lipid/water interface and possesses anti-inflammatory activity in skin inflammation models. 
  • Beta-adrenoceptor signaling and its control of cell replication in MDA-MB-231 human breast cancer cells. 
  • Biologic predictors of clinical improvement in rituximab-treated refractory myositis. 
  • Bombesin-like peptides and receptors in normal fetal baboon lung: roles in lung growth and maturation. 
  • Bronchiolitis by Any Other Name: Describing Bronchiolar Disorders from Inhalational Exposures. 
  • Budesonide nasal irrigations in the postoperative management of chronic rhinosinusitis. 
  • COG1410, a novel apolipoprotein E-based peptide, improves functional recovery in a murine model of traumatic brain injury. 
  • CT-guided cervical transforaminal steroid injections: where should the needle tip be located? 
  • Cellular FLIP Inhibits Myeloid Cell Activation by Suppressing Selective Innate Signaling. 
  • Changes in serum and synovial fluid biomarkers after acute injury (NCT00332254). 
  • Characteristics of patients treated for orbital cellulitis: An analysis of inpatient data. 
  • Characterization of porous, dexamethasone-releasing polyurethane coatings for glucose sensors. 
  • Childhood Arthritis and Rheumatology Research Alliance Consensus Clinical Treatment Plans for Juvenile Dermatomyositis with Persistent Skin Rash. 
  • Chondroitin sulphate inhibits NF-κB activity induced by interaction of pathogenic and damage associated molecules. 
  • Clinical and immunopathologic effects of swallowed fluticasone for eosinophilic esophagitis. 
  • Clinical outcomes and response of patients applying topical therapy for pyoderma gangrenosum: A prospective cohort study. 
  • Clinical pharmacology of benoxaprofen. 
  • Cogan's syndrome and development of ANCA-associated renal vasculitis after lengthy disease remission. 
  • Colchicine effectiveness in symptom and inflammation modification in knee osteoarthritis (COLKOA): study protocol for a randomized controlled trial. 
  • Combination therapy for early Alzheimer's disease: what are we waiting for? 
  • Comparison of cefuroxime with or without intranasal fluticasone for the treatment of rhinosinusitis. The CAFFS Trial: a randomized controlled trial. 
  • Con: Methylprednisolone is not indicated for patients during cardiopulmonary bypass. 
  • Conjunctival necrosis following the administration of subconjunctival corticosteroid. 
  • Consensus statement: aerosols and delivery devices. American Association for Respiratory Care. 
  • Consequences of intra-articular bleeding in haemophilia: science to clinical practice and beyond. 
  • Controlled release of anti-inflammatory agent alpha-MSH from neural implants. 
  • Controversies in the Management of Isolated Congenital Atrioventricular Block. 
  • Coronary artery thickening with mucosal lesions in Henoch-Schönlein purpura. 
  • Cryptococcal meningitis in patients with glioma: a report of two cases. 
  • Current management of pediatric inflammatory bowel disease. 
  • Current strategies for nonsurgical, arthroscopic, and minimally invasive surgical treatment of knee cartilage pathology. 
  • Cushing's syndrome after intra-articular and intradermal administration of triamcinolone acetonide in three pediatric patients. 
  • Cyclosporine, methotrexate, and prednisone compared with cyclosporine and prednisone for prevention of acute graft-vs.-host disease: effect on chronic graft-vs.-host disease and long-term survival. 
  • Cytomegalovirus keratitis after penetrating keratoplasty. 
  • Development and characterization of a fusion protein between thermally responsive elastin-like polypeptide and interleukin-1 receptor antagonist: sustained release of a local antiinflammatory therapeutic. 
  • Dexamethasone-coated neural probes elicit attenuated inflammatory response and neuronal loss compared to uncoated neural probes. 
  • Differential anti-inflammatory effects of LPS in susceptible and resistant mouse strains. 
  • Differential effectiveness of etanercept and infliximab in the treatment of ocular inflammation. 
  • Differential expression of substance P receptors in patients with Crohn's disease and ulcerative colitis. 
  • Diffuse alveolar hemorrhage: retrospective review of clinical outcome in allogeneic transplant recipients treated with aminocaproic acid. 
  • Do omega-3 fatty acids prevent atrial fibrillation after open heart surgery? A meta-analysis of randomized controlled trials. 
  • Do patient preferences influence decisions on treatment for patients with steroid-refractory ulcerative colitis? 
  • Dysfunction of inflammation-resolving pathways is associated with exaggerated postoperative cognitive decline in a rat model of the metabolic syndrome. 
  • Editorial comment. The value of intensive medical management of distal ureteral calculi in an effort to facilitate spontaneous stone passage. 
  • Effect of Body Habitus on Radiation Dose During CT Fluoroscopy-Guided Spine Injections. 
  • Effect of interleukin-1β inhibition with canakinumab on incident lung cancer in patients with atherosclerosis: exploratory results from a randomised, double-blind, placebo-controlled trial. 
  • Effect of statin dose on incidence of atrial fibrillation: data from the Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 (PROVE IT-TIMI 22) and Aggrastat to Zocor (A to Z) trials. 
  • Effects of C5 complement inhibitor pexelizumab on outcome in high-risk coronary artery bypass grafting: combined results from the PRIMO-CABG I and II trials. 
  • Effects of a Single Intra-Articular Injection of a Microsphere Formulation of Triamcinolone Acetonide on Knee Osteoarthritis Pain: A Double-Blinded, Randomized, Placebo-Controlled, Multinational Study. 
  • Effects of two nonsteroidal anti-inflammatory drugs, indomethacin and oxaprozin, on the kidney. 
  • Efficacy and safety of fluticasone propionate 0.005% ointment in the treatment of psoriasis. 
  • Efficacy of intranasal corticosteroids for acute sinusitis. 
  • Efficacy of pamidronate for osteoporosis in patients with cystic fibrosis following lung transplantation. 
  • Emerging targets in neuroinflammation-driven chronic pain. 
  • Emerging treatment options to improve cardiovascular outcomes in patients with acute coronary syndrome: focus on losmapimod. 
  • Equivalence of 2 effective graft-versus-host disease prophylaxis regimens: results of a prospective double-blind randomized trial. 
  • Esophagitis caused by nonsteroidal anti-inflammatory medication: case reports and review of the literature on pill-induced esophageal injury. 
  • Extreme Eyelid Lymphedema Associated With Rosacea (Morbihan Disease): Case Series, Literature Review, and Therapeutic Considerations. 
  • Fatal exserohilum meningitis and central nervous system vasculitis after cervical epidural methylprednisolone injection. 
  • For the patient. Do patients use prescribed medicine for osteoarthritis? 
  • GSK2193874 treatment at heatstroke onset reduced cell apoptosis in heatstroke mice. 
  • Gadolinium chloride alters the acinar distribution of phagocytosis and balance between pro- and anti-inflammatory cytokines. 
  • Gastrointestinal microbleeding: comparisons between benoxaprofen and other nonsteroidal antiinflammatory agents. 
  • Glucocorticoid-induced osteogenesis is negatively regulated by Runx2/Cbfa1 serine phosphorylation. 
  • Glucocorticoid-targeting of the adenylyl cyclase signaling pathway in the cerebellum of young vs. aged rats. 
  • Guidelines of care for the use of topical glucocorticosteroids. American Academy of Dermatology. 
  • Healing of experimental muscle strains and the effects of nonsteroidal antiinflammatory medication. 
  • Health-related quality of life and health service use among older adults with osteoarthritis. 
  • Heart xenograft survival with chimeric pig donors and modest immune suppression. 
  • High- and low-risk profiles for the development of multiple sclerosis within 10 years after optic neuritis: experience of the optic neuritis treatment trial. 
  • High-dose oral dexamethasone therapy for chronic childhood idiopathic thrombocytopenic purpura. 
  • Higher doses of mitoxantrone among men with hormone-refractory prostate carcinoma: a Cancer and Leukemia Group B study. 
  • Histochemical analyses of altered fetal lung development following single vs multiple courses of antenatal steroids. 
  • Host-Directed Therapies for Tuberculosis. 
  • Human test models for bioequivalence of topical corticosteroids: a review. 
  • Hydrocortisone with or without mitoxantrone in men with hormone-refractory prostate cancer: results of the cancer and leukemia group B 9182 study. 
  • Hydroxychloroquine-induced hyperpigmentation: the staining pattern. 
  • Iatrogenic fungal meningitis: tragedy repeated. 
  • Immunology of inflammatory bowel disease: summary of the proceedings of the Subcommittee on Immunosuppressive Use in IBD. 
  • Impact of perioperative dexamethasone on postoperative analgesia and side-effects: systematic review and meta-analysis. 
  • Inappropriate nonsteroidal anti-inflammatory drug use: prevalence and predictors. 
  • Increased nucleolar localization of SpiA3G in classically but not alternatively activated macrophages. 
  • Inflammation and thrombosis: roles of neutrophils, platelets and endothelial cells and their interactions in thrombus formation during sepsis. 
  • Inflammation in coronary artery disease. 
  • Inflammation, complement factor h, and age-related macular degeneration: the Multi-ethnic Study of Atherosclerosis. 
  • Inflammatory neuropathies: an update on evaluation and treatment. 
  • Infliximab to treat chronic noninfectious uveitis in children: retrospective case series with long-term follow-up. 
  • Inhaled steroids as prophylaxis for delayed pulmonary toxicity syndrome in breast cancer patients undergoing high-dose chemotherapy and autologous stem cell transplantation. 
  • Inhibition of endothelial activation: a new way to treat cerebral malaria? 
  • Inhibition of microglial superoxide anion production by isoproterenol and dexamethasone. 
  • Inhibition of murine dendritic cell activation by synthetic phosphorothioate oligodeoxynucleotides. 
  • Injectable Fluocinolone Acetonide Long-Acting Implant for Noninfectious Intermediate Uveitis, Posterior Uveitis, and Panuveitis: Two-Year Results. 
  • Interferon-regulated chemokine score associated with improvement in disease activity in refractory myositis patients treated with rituximab. 
  • Intranasal fluticasone associated with delayed tympanostomy tube placement in children with eustachian tube dysfunction. 
  • Intratympanic dexamethasone for sudden sensorineural hearing loss after failure of systemic therapy. 
  • Intravitreal Adalimumab for the Control of Breakthrough Intraocular Inflammation. 
  • Liquid ventilation. 
  • Long-term interleukin 10 therapy in chronic hepatitis C patients has a proviral and anti-inflammatory effect. 
  • MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy. 
  • Management of the unilateral shoulder impingement syndrome. 
  • Management of the unilateral shoulder impingement syndrome. 
  • Management of tumor bed cysts after chemotherapeutic wafer implantation. Report of four cases. 
  • Maternal autoantibody levels in congenital heart block and potential prophylaxis with antiinflammatory agents. 
  • Mechanism of Fibronectin Binding to Human Trabecular Meshwork Exosomes and Its Modulation by Dexamethasone. 
  • Medical and nutrition management of eosinophilic esophagitis in children. 
  • Methylphenidate-induced autoimmune hepatitis. 
  • Methylprednisolone reduces the inflammatory response to cardiopulmonary bypass in neonatal piglets: timing of dose is important. 
  • Modular nanotransporters for targeted intracellular delivery of drugs: folate receptors as potential targets. 
  • Monocyte receptors for the Fc portion of IgG are increased in systemic lupus erythematosus. 
  • Motor variant of chronic inflammatory demyelinating polyneuropathy in a child. 
  • Musculoskeletal syndromes associated with malignancy. 
  • Myasthenia gravis and pregnancy. 
  • Mycophenolate mofetil in AChR-antibody-positive myasthenia gravis: outcomes in 102 patients. 
  • Nanocarrier-mediated inhibition of macrophage migration inhibitory factor attenuates secondary injury after spinal cord injury. 
  • Neurogenic differentiation of murine and human adipose-derived stromal cells. 
  • Neuromuscular ultrasound findings in eosinophilic fasciitis: A case series and literature review. 
  • New and Pipeline Drugs for Gout. 
  • New and emerging treatments for patients with uveitis. 
  • Nucleic acid-binding polymers as anti-inflammatory agents. 
  • Nucleic acid-binding polymers as anti-inflammatory agents: reducing the danger of nuclear attack. 
  • One-year outcome of subacromial corticosteroid injection compared with manual physical therapy for the management of the unilateral shoulder impingement syndrome: a pragmatic randomized trial. 
  • Panniculitis in juvenile dermatomyositis. 
  • Patient demographics and health plan paid costs in chronic inflammatory demyelinating polyneuropathy. 
  • Perioperative methylprednisolone and outcome in neonates undergoing heart surgery. 
  • Pexelizumab and the APEX AMI trial. 
  • Pexelizumab for acute ST-elevation myocardial infarction in patients undergoing primary percutaneous coronary intervention: a randomized controlled trial. 
  • Phase 1 Randomized, Double-Blind, Placebo-Controlled Study to Determine the Safety, Tolerability, and Pharmacokinetics of a Single Escalating Dose and Repeated Doses of CN-105 in Healthy Adult Subjects. 
  • Phase IIa trial in Duchenne muscular dystrophy shows vamorolone is a first-in-class dissociative steroidal anti-inflammatory drug. 
  • Polymyositis as a manifestation of chronic graft-versus-host disease. 
  • Prevention of leg length discrepancy in young children with pauciarticular juvenile rheumatoid arthritis by treatment with intraarticular steroids. 
  • Proprotein Convertase Subtilisin/Kexin Type 9 Monoclonal Antibodies for Acute Coronary Syndrome: A Narrative Review. 
  • Prospects of antiviral and anti-inflammatory therapy for respiratory syncytial virus infection. 
  • Protection from lipopolysaccharide-induced lung injury by augmentation of airway S-nitrosothiols. 
  • Protective effect of nifedipine against carrageenan-induced inflammation. 
  • Protein Phosphatase 1α and Cofilin Regulate Nuclear Translocation of NF-κB and Promote Expression of the Anti-Inflammatory Cytokine Interleukin-10 by T Cells. 
  • Proteolytic activity and immunogenicity of oral bromelain within the gastrointestinal tract of mice. 
  • Racial differences in analgesic/anti-inflammatory medication adherence among patients with osteoarthritis. 
  • Racial differences in health care utilization among patients with osteoarthritis. 
  • Recalcitrant rhinosinusitis, innate immunity, and mannose-binding lectin. 
  • Recommendations for the management of herpes zoster. 
  • Recurrence of cardiac sarcoidosis in a heart transplant recipient. 
  • Refractory gout: what is it and what to do about it? 
  • Regulation of membrane-associated prostaglandin E2 synthase 1 in pregnant sheep intrauterine tissues by glucocorticoid and estradiol. 
  • Rituximab as treatment for anti-MuSK myasthenia gravis: Multicenter blinded prospective review. 
  • Role of adhesion molecules and vascular endothelium in the pathogenesis of sickle cell disease. 
  • Safety and pharmokinetics of triamcinolone hexacetonide in rabbit eyes. 
  • Sequential Sterile Intraocular Inflammation Associated With Consecutive Intravitreal Injections of Aflibercept and Ranibizumab. 
  • Sex-Dependent Glial Signaling in Pathological Pain: Distinct Roles of Spinal Microglia and Astrocytes. 
  • Simvastatin and atorvastatin improve behavioral outcome, reduce hippocampal degeneration, and improve cerebral blood flow after experimental traumatic brain injury. 
  • Sparstolonin B attenuates early liver inflammation in experimental NASH by modulating TLR4 trafficking in lipid rafts via NADPH oxidase activation. 
  • Spatial distribution and acute anti-inflammatory effects of Methylprednisolone after sustained local delivery to the contused spinal cord. 
  • Specificity and sensitivity of glucocorticoid signaling in health and disease. 
  • Spondyloarthritis in a patient with unilateral buttock pain and history of Crohn disease. 
  • Steroid treatment and the development of scoliosis in males with duchenne muscular dystrophy. 
  • Steroid-induced glaucoma in a young woman. 
  • Steroids for restenosis: strike three! 
  • Successful desensitization to carboplatin in patients with systemic hypersensitivity reactions. 
  • Synovial and systemic pharmacokinetics (PK) of triamcinolone acetonide (TA) following intra-articular (IA) injection of an extended-release microsphere-based formulation (FX006) or standard crystalline suspension in patients with knee osteoarthritis (OA). 
  • Systemic lupus erythematosus. 
  • Systemic lupus erythematosus. Diagnosis and treatment. 
  • TRPV4 inhibition counteracts edema and inflammation and improves pulmonary function and oxygen saturation in chemically induced acute lung injury. 
  • Tacrolimus dose requirements in African-American and Caucasian kidney transplant recipients on mycophenolate and prednisone. 
  • Targeted therapies and outcomes data: the inflammatory hypothesis matures. 
  • Tendinitis and other chronic tendinopathies. 
  • Terminal complement blockade with pexelizumab during coronary artery bypass graft surgery requiring cardiopulmonary bypass: a randomized trial. 
  • Tetomilast: new promise for phosphodiesterase-4 inhibitors? 
  • The Beneficial Therapy with Colchicine for Atherosclerosis via Anti-inflammation and Decrease in Hypertriglyceridemia. 
  • The C-terminal domain of A1/Bfl-1 regulates its anti-inflammatory function in human endothelial cells. 
  • The HIV-1 protease inhibitor nelfinavir activates PP2 and inhibits MAPK signaling in macrophages: a pathway to reduce inflammation. 
  • The effects of medications on bone. 
  • The importance of studying history: lessons learnt from a trial of tacrolimus in myasthenia gravis. 
  • The influence of food intake on the bioavailability of timegadine, a novel non-steroidal anti-inflammatory drug. 
  • The management of pediatric systemic lupus erythematosus. 
  • The novel apolipoprotein E-based peptide COG1410 improves sensorimotor performance and reduces injury magnitude following cortical contusion injury. 
  • The pharmacokinetics of timegadine and two of its metabolites after multiple oral dosing, and the effects of concomitant administration of ibuprofen. 
  • The predominance of membranoproliferative glomerulonephritis in childhood nephrotic syndrome in Ibadan, Nigeria. 
  • The presence of T-lymphocyte subpopulations (CD4 and CD8) in pterygia: evaluation of the inflammatory response. 
  • The protein binding of timegadine determined by equilibrium dialysis. 
  • The results of a randomized controlled trial of hydrocortisone in acute exacerbation of COPD. 
  • The role of oral beclometasone dipropionate in the treatment of gastrointestinal Graft-versus-Host Disease. 
  • The use of recombinant human activated protein C (drotrecogin alpha) in solid organ transplant recipients: case series and review of the literature. 
  • Therapeutic approaches to the treatment of rheumatoid disease. 
  • Therapy of inflammatory bowel disease: what to expect in the next decade. 
  • Thyroid Orbitopathy. 
  • Transient Receptor Potential Cation Channel Subfamily M Member 8 channels mediate the anti-inflammatory effects of eucalyptol. 
  • Transient complete lower facial nerve palsy after craniotomy for aneurysm clipping. 
  • Transient lumbosacral polyradiculopathy after prostatectomy: association with spinal stenosis. 
  • Treatment of seasonal allergic conjunctivitis with ophthalmic corticosteroids: in search of the perfect ocular corticosteroids in the treatment of allergic conjunctivitis. 
  • Unilateral supraglottic edema after the use of a laryngeal mask airway. 
  • Urticaria pigmentosa. Systemic evaluation and successful treatment with topical steroids. 
  • Use of targeted transversus abdominus plane blocks in pediatric patients with anterior cutaneous nerve entrapment syndrome. 
  • Utility of thiopurine methyltransferase genotyping and phenotyping, and measurement of azathioprine metabolites in the management of patients with autoimmune hepatitis. 
  • [Idiopathic hypertrophic pachymeningitis of the cavernous sinus mimicking meningioma with complete occlusion of the carotid artery]. 
  • [IgA pemphigus. Successful treatment with mycophenolate mofetil]. 
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  Keywords of People

  • Milano, Carmelo Alessio, Professor of Surgery, Surgery, Cardiovascular and Thoracic Surgery
  • Preminger, Glenn Michael, James F. Glenn, M.D. Professor of Urology, Surgery
  • Warner, David Samuel, Distinguished Professor of Anesthesiology, in the School of Medicine, Neurobiology