Anticonvulsants

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  Subject Areas on Research

  • (Aryloxy)aryl semicarbazones and related compounds: a novel class of anticonvulsant agents possessing high activity in the maximal electroshock screen. 
  • 17beta-Nitro-5alpha-androstan-3alpha-ol and its 3beta-methyl derivative: neurosteroid analogs with potent anticonvulsant and anxiolytic activities. 
  • 3-Halo-5,7-dimethylpyrazolo [1,5-a]pyrimidines, a nonbenzodiazepinoid class of antianxiety agents devoid of potentiation of central nervous system depressant effects of ethanol or barbiturates. 
  • A case of delirium, motor disturbances, and autonomic dysfunction due to baclofen and tizanidine withdrawal: a review of the literature. 
  • A case of sustained massive gabapentin overdose without serious side effects. 
  • A design for the prospective evaluation of the efficacy and toxicity of antiepileptic drugs in adults. 
  • A double-blind combination study of clonazepam with sertraline in obsessive-compulsive disorder. 
  • A generalized estimating equation approach for modeling random length binary vector data. 
  • A grease-gap method for studying the excitatory amino acid pharmacology of CA1 hippocampal pyramidal cells. 
  • A method of quantification for the evaluation of antiepileptic drug therapy. 
  • A phase I/II trial of pazopanib in combination with lapatinib in adult patients with relapsed malignant glioma. 
  • A preliminary study of lamotrigine for the treatment of posttraumatic stress disorder. 
  • A review of the effect of anticonvulsant medications on bone mineral density and fracture risk. 
  • ALSUntangled 48: Perampanel (Fycompa). 
  • Addition of Cannabidiol to Current Antiepileptic Therapy Reduces Drop Seizures in Children and Adults With Treatment-Resistant Lennox-Gastaut Syndrome. 
  • Adjunctive lamotrigine for partial seizures in patients aged 1 to 24 months. 
  • Age, dose, and environmental temperature are risk factors for topiramate-related hyperthermia. 
  • Alternating hemiplegia of childhood: clinical manifestations and long-term outcome. 
  • An integrated risk model stratifying seizure risk following brain tumor resection among seizure-naive patients without antiepileptic prophylaxis. 
  • Anti-seizure and anti-epileptogenic effect of gamma-vinyl gamma-aminobutyric acid in amygdaloid kindling. 
  • Anticonvulsant Prophylaxis and Steroid Use in Adults With Metastatic Brain Tumors: ASCO and SNO Endorsement of the Congress of Neurological Surgeons Guidelines. 
  • Anticonvulsant action and long-term effects of gabapentin in the immature brain. 
  • Anticonvulsant action of intranigral gamma-vinyl-GABA: role of nonadrenergic neurotransmission. 
  • Anticonvulsant and antiepileptogenic actions of MK-801 in the kindling and electroshock models. 
  • Anticonvulsant prophylaxis and steroid use in adults with metastatic brain tumors: summary of SNO and ASCO endorsement of the Congress of Neurological Surgeons guidelines. 
  • Anticonvulsant-like actions of baclofen in the rat hippocampal slice. 
  • Anticonvulsants for behavioral and psychological symptoms in dementia: protocol for a systematic review. 
  • Antiepileptic Drug Teratogenicity and De Novo Genetic Variation Load. 
  • Antiepileptic drugs prevent seizures in hyperbaric oxygen: A novel model of epileptiform activity. 
  • Antiepileptic effects of GABAb receptor activation in area CA3 of rat hippocampus. 
  • Antiepileptics in migraine prophylaxis: an updated Cochrane review. 
  • Antiepileptics other than gabapentin, pregabalin, topiramate, and valproate for the prophylaxis of episodic migraine in adults. 
  • Antiepileptogenesis and disease modification: Clinical and regulatory issues. 
  • Antiepileptogenic effects of conventional anticonvulsants in the kindling model of epilespy. 
  • Antimicrobials and Antiepileptics Are the Leading Causes of Idiosyncratic Drug-induced Liver Injury in American Children. 
  • Antiseizure Medication Withdrawal in Seizure-Free Patients: Practice Advisory Update Summary: Report of the AAN Guideline Subcommittee. 
  • Antiseizure effects of TrkB kinase inhibition. 
  • Approach to epilepsy in children. 
  • Assessment of the effects of lacosamide on sleep parameters in healthy subjects. 
  • Association of Time to Treatment With Short-term Outcomes for Pediatric Patients With Refractory Convulsive Status Epilepticus. 
  • Association of guideline publication and delays to treatment in pediatric status epilepticus. 
  • Attenuation of epileptogenesis: proactive effect of a single epinephrine injection of amygdaloid kindling. 
  • Atypical presentation of Henoch-Schönlein purpura. 
  • Baclofen suppresses bursting activity induced in hippocampal slices by differing convulsant treatments. 
  • Barbiturate-related connective tissue disorders. 
  • Behavioral side effects of gabapentin in children. 
  • Benzodiazepine administration patterns before escalation to second-line medications in pediatric refractory convulsive status epilepticus. 
  • Bidirectional interaction of valproate and lamotrigine in healthy subjects. 
  • Biological therapies for posttraumatic stress disorder: an overview. 
  • Blockade of hyperbaric oxygen induced seizures by excitatory amino acid antagonists. 
  • Brexanolone as adjunctive therapy in super-refractory status epilepticus. 
  • CYP2C9*1B promoter polymorphisms, in linkage with CYP2C19*2, affect phenytoin autoinduction of clearance and maintenance dose. 
  • Carbamazepine-induced toxic effects and HLA-B*1502 screening in Taiwan. 
  • Carisbamate, a novel antiepileptic candidate compound, attenuates alcohol intake in alcohol-preferring rats. 
  • Causes of treatment failure with antiepileptic drugs vary over time. 
  • Causes, prevention, and treatment of post-traumatic epilepsy. 
  • Cerebral blood flow velocity response to magnesium sulfate in patients after subarachnoid hemorrhage. 
  • Changes in sphingomyelinases, ceramide, Bax, Bcl(2), and caspase-3 during and after experimental status epilepticus. 
  • Characteristics of Neonates with Cardiopulmonary Disease Who Experience Seizures: A Multicenter Study. 
  • Characteristics of valproic acid resistant juvenile myoclonic epilepsy. 
  • Clinical characteristics of antiepileptic-induced liver injury in patients from the DILIN prospective study. 
  • Clinical utility of genetic testing in pediatric drug-resistant epilepsy: a pilot study. 
  • Comments on "Addition of lamotrigine to valproic acid: a successful outcome in a case of rapid-cycling bipolar affective disorder". 
  • Common risk allele in aromatic antiepileptic-drug induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Han Chinese. 
  • Community consultation for prehospital research: experiences of study coordinators and principal investigators. 
  • Comparative efficacy of antiepileptic drugs. 
  • Comparison of brand versus generic antiepileptic drug adverse event reporting rates in the U.S. Food and Drug Administration Adverse Event Reporting System (FAERS). 
  • Comparison of cognitive-behavioral therapy and clonazepam for treating periodic limb movement disorder. 
  • Comparison of valproate and phenobarbital treatment after status epilepticus in rats. 
  • Conclusions inconsistent with results with amphetamines and divalproex. 
  • Cost-effectiveness of HLA-B*1502 genotyping in adult patients with newly diagnosed epilepsy in Singapore. 
  • Critical Assessment of Myelography Practices: A Call for Rational Guideline Revision. 
  • Current and Emerging Therapies of Severe Epileptic Encephalopathies. 
  • Current perspectives on pyridoxine-dependent seizures. 
  • Demographics and diagnosis of pyridoxine-dependent seizures. 
  • Development of new pharmacological agents for epilepsy: lessons from the kindling model. 
  • Dietary and medication adjustments to improve seizure control in patients treated with the ketogenic diet. 
  • Difficult behaviors in long-term care patients with dementia. 
  • Difficult behaviors in long-term care patients with dementia. 
  • Discontinuation of clonazepam in the treatment of social phobia. 
  • Discontinuing antiepileptic drugs in children with epilepsy. A comparison of a six-week and a nine-month taper period. 
  • Discovery and development of lamotrigine for bipolar disorder: a story of serendipity, clinical observations, risk taking, and persistence. 
  • Does accounting for seizure frequency variability increase clinical trial power? 
  • Does age affect response to quinidine in patients with KCNT1 mutations? Report of three new cases and review of the literature. 
  • Dramatic Response After Lamotrigine in a Patient With Epileptic Encephalopathy and a De NovoCACNA1A Variant. 
  • Drug Trials in Status Epilepticus: Current Evidence and Future Concepts. 
  • Drug interaction between carbapenems and extended-release divalproex sodium in a patient with schizoaffective disorder. 
  • Drug rechallenge following drug-induced liver injury. 
  • Drug-drug interactions in older adults: which ones matter? 
  • ECT in the treatment of status epilepticus. 
  • Effect of CYP3A-inducing anti-epileptics on sorafenib exposure: results of a phase II study of sorafenib plus daily temozolomide in adults with recurrent glioblastoma. 
  • Effect of Cord Blood Magnesium Level at Birth on Non-neurologic Neonatal Outcomes. 
  • Effect of Ezogabine on Cortical and Spinal Motor Neuron Excitability in Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial. 
  • Effect of antiepileptic drugs on bone density in ambulatory patients. 
  • Effectiveness of antiepileptic drugs for the treatment of bipolar disorder: findings from a systematic review. 
  • Effects of NMDA receptor antagonists and body temperature in the gerbil carotid occlusion model of transient forebrain ischemia. 
  • Effects of amphetamines and small related molecules on recovery after stroke in animals and man. 
  • Effects of creatine and cyclocreatine supplementation on kainate induced injury in pre-pubescent rats. 
  • Effects of intranigral application of clinically-effective anticonvulsants on electroshock-induced seizures. 
  • Effects of magnesium sulfate in kainic acid-induced status epilepticus. 
  • Effects of nimodipine on the behavioral sequalae of experimental status epilepticus in prepubescent rats. 
  • Effects of religiosity and religious coping on medication adherence and quality of life among people with epilepsy. 
  • Efficacy of felbamate in therapy for partial epilepsy in children. 
  • Efficacy of gabapentin therapy in children with refractory partial seizures. 
  • Efficacy of the ketogenic diet in Lennox-Gastaut syndrome: a retrospective review of one institution's experience and summary of the literature. 
  • Efficacy, tolerability, and kinetics of lamotrigine in infants. 
  • Emergency management of the patient with seizures. 1. Classification and treatment system, common seizure disorders. 
  • Emergency management of the patient with seizures. 1. Generalized status epilepticus. 
  • Enantiomeric propanolamines as selective N-methyl-D-aspartate 2B receptor antagonists. 
  • Epilepsy in KCNH1-related syndromes. 
  • Epilepsy. 
  • Evaluation of Levetiracetam Dosing Strategies for Seizure Prophylaxis Following Traumatic Brain Injury. 
  • Evidence implicating alpha-2 adrenergic receptors in the anticonvulsant action of intranigral muscimol. 
  • Evidence-based mental health use of anticonvulsants during pregnancy. 
  • Extended-release carbamazepine capsules as monotherapy in bipolar disorder : pooled results from two randomised, double-blind, placebo-controlled trials. 
  • Factors associated with long-term outcomes in pediatric refractory status epilepticus. 
  • Factors associated with treatment delays in pediatric refractory convulsive status epilepticus. 
  • Fatal Cerebral Edema in a Child With COVID-19. 
  • Fatality from hepatitis A in a child taking valproate. 
  • First-line medication dosing in pediatric refractory status epilepticus. 
  • Five percent CO₂ is a potent, fast-acting inhalation anticonvulsant. 
  • Frontal lobe trauma in the elderly. Personality changes aren't always dementia. 
  • Gabapentin in the treatment of mental illness: the echo chamber of the case series. 
  • Gabapentin in the treatment of refractory partial epilepsy in children with intellectual disability. 
  • Gabapentin or pregabalin for the prophylaxis of episodic migraine in adults. 
  • Gaps and opportunities in refractory status epilepticus research in children: a multi-center approach by the Pediatric Status Epilepticus Research Group (pSERG). 
  • Genetic and environmental correlates of topiramate-induced cognitive impairment. 
  • Genetic predisposition of life-threatening antiepileptic-induced skin reactions. 
  • Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions. 
  • HLA-A*3101 and carbamazepine-induced hypersensitivity reactions in Europeans. 
  • Hippocampal volume measurement in older adults with bipolar disorder. 
  • Hospital Emergency Treatment of Convulsive Status Epilepticus: Comparison of Pathways From Ten Pediatric Research Centers. 
  • Hospital-based epilepsy care in Uganda: A prospective study of three major public referral hospitals. 
  • Hypothesis: Presymptomatic treatment of Sturge-Weber Syndrome With Aspirin and Antiepileptic Drugs May Delay Seizure Onset. 
  • Improved sexual function in three men taking lamotrigine for epilepsy. 
  • In vivo profile of ICA-27243 [N-(6-chloro-pyridin-3-yl)-3,4-difluoro-benzamide], a potent and selective KCNQ2/Q3 (Kv7.2/Kv7.3) activator in rodent anticonvulsant models. 
  • Increased Antiseizure Effectiveness with Tiagabine Combined with Sodium Channel Antagonists in Mice Exposed to Hyperbaric Oxygen. 
  • Inhibiting glycolysis to reduce seizures: how it might work. 
  • Inhibitory simple partial (non-convulsive) status epilepticus after intracranial surgery. 
  • Initial EEG predicts outcomes in a trial of levetiracetam vs. fosphenytoin for seizure prevention. 
  • Institutional Pediatric Convulsive Status Epilepticus Protocol Decreases Time to First and Second Line Anti-Seizure Medication Administration. 
  • Interaction of nicotinic and histamine H(3) systems in the radial-arm maze repeated acquisition task. 
  • Interactions between sleep and epilepsy. 
  • Intravenous ganaxolone for the treatment of refractory status epilepticus: Results from an open-label, dose-finding, phase 2 trial. 
  • Intravenous phenytoin is an effective anticonvulsant in the kindling model. 
  • Kainic acid seizures and neuronal cell death: insights from studies of selective lesions and drugs. 
  • Lacosamide improves outcome in a murine model of traumatic brain injury. 
  • Lacosamide in status epilepticus: Update on the TRENdS study. 
  • Lamotrigine as add-on therapy in schizophrenia: results of 2 placebo-controlled trials. 
  • Lamotrigine for bipolar disorder and comorbid cocaine dependence: a replication and extension study. 
  • Lamotrigine in absence and primary generalized epilepsies. 
  • Lamotrigine-induced blepharospasm. 
  • Landau-Kleffner syndrome: consistent response to repeated intravenous gamma-globulin doses: a case report. 
  • Letter: Antiepileptogenic and neuroprotective effects of erythropoietin: recent data. 
  • Levetiracetam for partial seizures: results of a double-blind, randomized clinical trial. 
  • Levetiracetam in children with refractory status epilepticus. 
  • Levetiracetam in social phobia: a placebo controlled pilot study. 
  • Levetiracetam versus (fos)phenytoin for seizure prophylaxis in pediatric patients with intracranial hemorrhage. 
  • Levocarnitine-induced hypophosphatemia in a hemodialysis patient with acute valproic acid toxicity. 
  • Long-term safety and efficacy in patients with uncontrolled partial-onset seizures treated with adjunctive lacosamide: results from a Phase III open-label extension trial. 
  • Long-term tolerability and efficacy of lamotrigine in infants 1 to 24 months old. 
  • Long-term tolerability, pharmacokinetic and preliminary efficacy study of lamotrigine in patients with resistant partial seizures. 
  • Low-grade gliomas associated with intractable epilepsy: seizure outcome utilizing electrocorticography during tumor resection. 
  • Management of Landau-Kleffner syndrome. 
  • Managing the epileptic patient. 
  • Measurement of felbamate by wide-bore capillary gas chromatography and flame ionization detection. 
  • Medical treatment of patients with infantile spasms. 
  • Medical treatment of pregnancy hypertension. 
  • Mesial temporal sclerosis: pathogenesis and significance. 
  • Modest increase in extracellular potassium unmasks effect of recurrent mossy fiber growth. 
  • Multicenter Research Data of Epilepsy Management in Patients With Sturge-Weber Syndrome. 
  • NMDA antagonists differentiate epileptogenesis from seizure expression in an in vitro model. 
  • Neonatal nonepileptic myoclonus is a prominent clinical feature of KCNQ2 gain-of-function variants R201C and R201H. 
  • Neurologic complications after allogeneic marrow transplantation for sickle cell anemia. 
  • Neuroprotective effect of felbamate after kainic acid-induced status epilepticus. 
  • New waves of research in the epilepsies: crossing into the third millennium. 
  • Nocturnal epilepsy in adults. 
  • Normalization of quality of life three years after temporal lobectomy: a controlled study. 
  • Novel therapies for epilepsy in the pipeline. 
  • Oculogyric crises secondary to lamotrigine overdosage. 
  • Open-label pilot trial of levetiracetam for cramps and spasticity in patients with motor neuron disease. 
  • Opioid and benzodiazepine use during therapeutic hypothermia in encephalopathic neonates. 
  • Osteoporosis piece of multi-morbidity puzzle in geriatric care. 
  • Panic disorder and social phobia: current treatments and new strategies. 
  • Pharmacokinetics of levetiracetam. 
  • Pharmacological agents to treat severe neuropsychiatric symptoms in major neurocognitive disorders. 
  • Pharmacotherapy in stroke rehabilitation. 
  • Pharmacotherapy of posttraumatic stress disorder: treatment options, long-term follow-up, and predictors of outcome. 
  • Phase 2 study of sodium phenylbutyrate in ALS. 
  • Phase I study of SU5416, a small molecule inhibitor of the vascular endothelial growth factor receptor (VEGFR) in refractory pediatric central nervous system tumors. 
  • Phase II trial of bevacizumab and erlotinib in patients with recurrent malignant glioma. 
  • Phenobarbital and temperature profile during hypothermia for hypoxic-ischemic encephalopathy. 
  • Phenytoin overview--metabolite interference in some immunoassays could be clinically important: results of a College of American Pathologists study. 
  • Phenytoin, levetiracetam, and pregabalin in the acute management of refractory status epilepticus in patients with brain tumors. 
  • Placebo-controlled study of the efficacy and safety of lamotrigine in patients with partial seizures. U.S. Lamotrigine Protocol 0.5 Clinical Trial Group. 
  • Pneumocephaly from epidural anesthesia. 
  • Population Pharmacokinetics and Exploratory Exposure-Response Relationships of Diazepam in Children Treated for Status Epilepticus. 
  • Population Pharmacokinetics and Exploratory Pharmacodynamics of Lorazepam in Pediatric Status Epilepticus. 
  • Possible induction of West syndrome by oxcarbazepine therapy in a patient with complex partial seizures. 
  • Post-traumatic stress disorder: an evaluation of existing pharmacotherapies and new strategies. 
  • Postpartum seizure prophylaxis: using maternal clinical parameters to guide therapy. 
  • Potential effects of common drugs on stroke recovery. 
  • Potential hepatotoxicity of lamotrigine. 
  • Potential role of pregabalin in the treatment of lithium-induced tremor: a case report. 
  • Predictors of bone density in ambulatory patients on antiepileptic drugs. 
  • Preeclampsia into eclampsia: toward a new paradigm. 
  • Pregabalin in generalized anxiety disorder: a placebo-controlled trial. 
  • Principles of drug treatment in children. 
  • Proconvulsant and anticonvulsant properties of ethanol: studies of electrographic seizures in vitro. 
  • Prospective, randomized, single-blinded comparative trial of intravenous levetiracetam versus phenytoin for seizure prophylaxis. 
  • Pseudoseizure manifestations in two preschool age children. 
  • Psychiatric and medical comorbidities of bipolar disorder. 
  • Pyridoxine-dependent epilepsy and pyridoxine phosphate oxidase deficiency: unique clinical symptoms and non-specific EEG characteristics. 
  • Pyridoxine-dependent seizures and cognition in adulthood. 
  • Quality of Life in Children With Sturge-Weber Syndrome. 
  • RNA aptamer-based functional ligands of the neurotrophin receptor, TrkB. 
  • Randomized trial of lacosamide versus fosphenytoin for nonconvulsive seizures. 
  • Randomized, placebo-controlled trial of mixed amphetamine salts for symptoms of comorbid ADHD in pediatric bipolar disorder after mood stabilization with divalproex sodium. 
  • Re: Epilepsy-associated bone mineral density loss should be prevented. 
  • Refractory Status Epilepticus in Children: Intention to Treat With Continuous Infusions of Midazolam and Pentobarbital. 
  • Refractory calculation-induced idiopathic generalized epilepsy: a case report and review of the literature. 
  • Refractory status epilepticus in children with and without prior epilepsy or status epilepticus. 
  • Relationship of carbamazepine reduction rate to seizure frequency during inpatient telemetry. 
  • Response of infantile spasms to levetiracetam. 
  • Response to antiseizure medications in neonates with acute symptomatic seizures. 
  • Role of analgesic adjuncts in postoperative pain management. 
  • Routine therapeutic monitoring of lamotrigine in epileptic patients using a simple and rapid high performance liquid chromatographic technique. 
  • Safety and pharmacokinetics of dose-intensive imatinib mesylate plus temozolomide: phase 1 trial in adults with malignant glioma. 
  • Safety of Early Discontinuation of Antiseizure Medication After Acute Symptomatic Neonatal Seizures. 
  • Seizure Control in Neonates Undergoing Screening vs Confirmatory EEG Monitoring. 
  • Seizure control in patients with epilepsy: the physician vs. medication factors. 
  • Seizure control in patients with idiopathic generalized epilepsies: EEG determinants of medication response. 
  • Seizures and epilepsy after ischemic stroke. 
  • Selective suppression of in vitro electrographic seizures by low-dose tetrodotoxin: a novel anticonvulsant effect. 
  • Sertraline-induced potentiation of the CYP3A4-dependent neurotoxicity of carbamazepine: an in vitro study. 
  • Serum sodium levels and related treatment-emergent adverse events during eslicarbazepine acetate use in adults with epilepsy. 
  • Shared and restricted T-cell receptor use is crucial for carbamazepine-induced Stevens-Johnson syndrome. 
  • Simple high-performance liquid chromatographic method to monitor vigabatrin, and preliminary review of concentrations determined in epileptic patients. 
  • Social phobia: issues in assessment and management. 
  • Stereological analysis of GluR2-immunoreactive hilar neurons in the pilocarpine model of temporal lobe epilepsy: correlation of cell loss with mossy fiber sprouting. 
  • Stiripentol in Dravet syndrome: results of a retrospective U.S. study. 
  • Super-Refractory Status Epilepticus in Children: A Retrospective Cohort Study. 
  • Symptomatic antiepileptic drug associated vitamin D deficiency in noninstitutionalized patients: an under-diagnosed disorder. 
  • T-cell receptor and carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis: understanding a hypersensitivity reaction. 
  • Targeting BDNF/TrkB pathways for preventing or suppressing epilepsy. 
  • The association of anticonvulsant use with fractures in spinal cord injury. 
  • The drug MK-801 attenuates the development, but not the expression, of long-term potentiation and stimulus train-induced bursting in hippocampal slices. 
  • The effects of magnesium sulfate on maternal and fetal platelet aggregation. 
  • The name game: lamivudine-lamotrigine dispensing error presenting as human immunodeficiency virus-associated fever of unknown origin. 
  • The newer antiepileptic drugs: carbamazepine and valproic acid. 
  • The prepuce as a donor site for reconstruction of an extravasation injury to the foot in a newborn. 
  • The role of GABAB receptor activation in absence seizures of lethargic (lh/lh) mice. 
  • The use of antiepileptic drugs in bipolar disorders: a review based on evidence from controlled trials. 
  • Therapeutic Index Estimation of Antiepileptic Drugs: A Systematic Literature Review Approach. 
  • Therapy of infantile spasms: new opportunities and emerging challenges. 
  • Therapy of seizures associated with stroke. 
  • Three children with a syndrome of obesity and overgrowth, atypical psychosis, and seizures: a problem in neuropsychopharmacology. 
  • Time from convulsive status epilepticus onset to anticonvulsant administration in children. 
  • Time to Treatment in Pediatric Convulsive Refractory Status Epilepticus: The Weekend Effect. 
  • Topiramate for the prophylaxis of episodic migraine in adults. 
  • Topiramate monotherapy as broad-spectrum antiepileptic drug in a naturalistic clinical setting. 
  • Topiramate-induced confusion following a single ingestion of 400 mg. 
  • Treatment of Recurrent Electrographic Nonconvulsive Seizures (TRENdS) study. 
  • Two randomized vitamin D trials in ambulatory patients on anticonvulsants: impact on bone. 
  • Two randomized vitamin D trials in ambulatory patients on anticonvulsants: impact on bone. 
  • Two studies evaluating irinotecan treatment for recurrent malignant glioma using an every-3-week regimen. 
  • Understanding therapeutic equivalence in epilepsy. 
  • Use of Therapeutic Drug Monitoring, Electronic Health Record Data, and Pharmacokinetic Modeling to Determine the Therapeutic Index of Phenytoin and Lamotrigine. 
  • Use of lamotrigine in a patient with a clozapine-related seizure. 
  • Use of pregabalin for nonconvulsive seizures and nonconvulsive status epilepticus. 
  • Use of the Biopharmaceutics Drug Disposition Classification System (BDDCS) to Help Predict the Occurrence of Idiosyncratic Cutaneous Adverse Drug Reactions Associated with Antiepileptic Drug Usage. 
  • Utility of levetiracetam in patients with subarachnoid hemorrhage. 
  • Valproate (valproic acid or sodium valproate or a combination of the two) for the prophylaxis of episodic migraine in adults. 
  • Valproate-associated carnitine deficiency and malignant cerebral edema in the absence of hepatic failure. 
  • Weight changes in obese adults 6-months after discontinuation of double-blind zonisamide or placebo treatment. 
  • West syndrome in tuberous sclerosis complex. 
  • What are the new treatments for bipolar disorder? 
  • Young Male With Seizure and Hypoxia. 
  • Zonisamide for weight loss in obese adults: a randomized controlled trial. 
  • Zonisamide in the treatment of binge eating disorder with obesity: a randomized controlled trial. 
  • Zonisamide prevents olanzapine-associated hyperphagia, weight gain, and elevated blood glucose in rats. 
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  Keywords of People

  • Laskowitz, Daniel Todd, Professor of Neurology, Duke Science & Society
  • Lee, Richard H., Assistant Professor of Medicine, Medicine, Endocrinology, Metabolism, and Nutrition
  • McLendon, Roger Edwin, Professor of Pathology, Pathology
  • Sampson, John Howard, Robert H., M.D. and Gloria Wilkins Professor of Neurosurgery, in the School of Medicine, Biomedical Engineering