Antiemetics

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  Subject Areas on Research

  • A comparison of ondansetron with promethazine for treating postoperative nausea and vomiting in patients who received prophylaxis with ondansetron: a retrospective database analysis. 
  • A comparison of the efficacy, safety, and patient satisfaction of ondansetron versus droperidol as antiemetics for elective outpatient surgical procedures. S3A-409 and S3A-410 Study Groups. 
  • A double-blind, placebo-controlled trial of four fixed rate infusion regimens of phenylephrine for hemodynamic support during spinal anesthesia for cesarean delivery. 
  • A phase I trial of olanzapine (Zyprexa) for the prevention of delayed emesis in cancer patients: a Hoosier Oncology Group study. 
  • A randomized comparison of a multimodal management strategy versus combination antiemetics for the prevention of postoperative nausea and vomiting. 
  • A randomized controlled comparison of electro-acupoint stimulation or ondansetron versus placebo for the prevention of postoperative nausea and vomiting. 
  • A randomized double blind study to evaluate efficacy of palonosetron with dexamethasone versus palonosetron alone for prevention of postoperative and postdischarge nausea and vomiting in subjects undergoing laparoscopic surgeries with high emetogenic risk. 
  • A randomized trial of phenylephrine infusion versus bolus dosing for nausea and vomiting during Cesarean delivery in obese women. 
  • A randomized, double-blind comparison of ondansetron versus placebo for prevention of nausea and vomiting after infratentorial craniotomy. 
  • A randomized, double-blinded comparison of ondansetron, droperidol, and placebo for prevention of postoperative nausea and vomiting after supratentorial craniotomy. 
  • Adherence to antiemetic guidelines in patients with malignant glioma: a quality improvement project to translate evidence into practice. 
  • American Society of Clinical Oncology 2013 top five list in oncology. 
  • Analgesic and antiemetic needs following minimally invasive vs open staging for endometrial cancer. 
  • Anaphylactoid reaction due to the administration of ondansetron in a pediatric neurosurgical patient. 
  • Antiemetics added to phenylephrine infusion during cesarean delivery: a randomized controlled trial. 
  • Antiemetics: American Society of Clinical Oncology clinical practice guideline update. 
  • Appropriate Use of Antiemetics to Prevent Chemotherapy-Induced Nausea and Vomiting. 
  • Aprepitant for the Treatment of Chronic Refractory Pruritus. 
  • CON: Postoperative nausea and vomiting database research: limitations and opportunities. 
  • Cancer recurrence and hyperglycemia with dexamethasone for postoperative nausea and vomiting prophylaxis: more moot points? 
  • Chemotherapy-induced nausea and vomiting (CINV) and adherence to antiemetic guidelines: results of a survey of oncology nurses. 
  • Chemotherapy-induced nausea and vomiting. 
  • Children's coping strategies for chemotherapy-induced nausea and vomiting. 
  • Combination antiemetics: what is the evidence? 
  • Comment: Promethazine adverse events after implementation of a medication shortage interchange. 
  • Comparison of inhaled isopropyl alcohol and intravenous ondansetron for treatment of postoperative nausea. 
  • Comparison of postoperative nausea between benign and malignant brain tumor patients undergoing awake craniotomy: a retrospective analysis. 
  • Consensus guidelines for managing postoperative nausea and vomiting. 
  • Controlling emesis: evolving challenges, novel strategies. 
  • Cost-effectiveness of prophylactic antiemetic therapy with ondansetron, droperidol, or placebo. 
  • Determination of plasma concentrations of propofol associated with 50% reduction in postoperative nausea. 
  • Dexamethasone for the prophylaxis of postoperative nausea and vomiting associated with neuraxial morphine administration: a systematic review and meta-analysis. 
  • Does midline shift predict postoperative nausea in brain tumor patients undergoing awake craniotomy? A retrospective analysis. 
  • Double-blind comparison of granisetron, promethazine, or a combination of both for the prevention of postoperative nausea and vomiting in females undergoing outpatient laparoscopies. 
  • Evidence-based management of postoperative nausea and vomiting: a review. 
  • Examining racial variation in antiemetic use and post-chemotherapy health care utilization for nausea and vomiting among breast cancer patients. 
  • Food and drug administration black box warning on the perioperative use of droperidol: a review of the cases. 
  • Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. 
  • Gastrointestinal symptoms in cancer patients with advanced disease: new methodologies, insights, and a proposed approach. 
  • Haloperidol for postoperative nausea and vomiting: are we reinventing the wheel? 
  • Haloperidol plus ondansetron versus ondansetron alone for prophylaxis of postoperative nausea and vomiting. 
  • Haloperidol versus ondansetron for prophylaxis of postoperative nausea and vomiting. 
  • Impact of data by Fujii and colleagues on the meta-analysis of metoclopramide for antiemetic prophylaxis in women undergoing Caesarean delivery under neuraxial anaesthesia. 
  • Impact of intraoperative dexmedetomidine on postoperative analgesia following gynecologic surgery. 
  • Impact of postoperative nausea and vomiting prophylaxis with dexamethasone on the risk of recurrence of endometrial cancer. 
  • Improving Adherence to Evidence-Based Guidelines for Chemotherapy-Induced Nausea and Vomiting. 
  • Influence of hepatic and intestinal cytochrome P4503A activity on the acute disposition and effects of oral transmucosal fentanyl citrate. 
  • Intraoperative colloid administration reduces postoperative nausea and vomiting and improves postoperative outcomes compared with crystalloid administration. 
  • Intravenous ondansetron in established postoperative emesis in children. S3A-381 Study Group. 
  • Long-acting serotonin antagonist (Palonosetron) and the NK-1 receptor antagonists: does extended duration of action improve efficacy? 
  • Low-dose naloxone infusion for the treatment of intractable nausea and vomiting after intrathecal morphine in a parturient. 
  • Management of postdischarge nausea and vomiting after ambulatory surgery. 
  • Metoclopramide for nausea and vomiting prophylaxis during and after Caesarean delivery: a systematic review and meta-analysis. 
  • Metoclopramide-induced tardive respiratory dyskinesia. 
  • Midazolam for Anxiolysis and Postoperative Nausea and Vomiting Prophylaxis: Can We Kill Two Birds with One Stone? 
  • Midazolam--an anti-emetic? 
  • Midtrimester abortion induced by serial intramuscular injections of 15(S)-15-methyl-prostaglandin F2alpha. 
  • Modification of the pharmacokinetics of high-dose cyclophosphamide and cisplatin by antiemetics. 
  • Periprocedural outcomes comparing fibroid embolization and focused ultrasound: a randomized controlled trial and comprehensive cohort analysis. 
  • Pharmacotherapy of postoperative nausea and vomiting. 
  • Phase II study of docetaxel in advanced soft tissue sarcomas. 
  • Pilot study of aprepitant for prevention of post-ERCP pancreatitis in high risk patients: a phase II randomized, double-blind placebo controlled trial. 
  • Postoperative Pain Scores and Narcotic Use in Robotic-assisted Versus Laparoscopic Hysterectomy for Endometrial Cancer Staging. 
  • Postoperative blood sugars and use of starches - a reply. 
  • Postoperative hyperglycemia after 4- vs 8-10-mg dexamethasone for postoperative nausea and vomiting prophylaxis in patients with type II diabetes mellitus: a retrospective database analysis. 
  • Postoperative nausea and vomiting following inpatient surgeries in a teaching hospital: a retrospective database analysis. 
  • Postoperative nausea and vomiting--can it be eliminated? 
  • Preoperative Risk Assessment to Guide Prophylaxis and Reduce the Incidence of Postoperative Nausea and Vomiting. 
  • Preventing chemotherapy-induced nausea and vomiting with netupitant/palonosetron, the first fixed combination antiemetic: current and future perspective. 
  • Pro: The Food and Drug Administration Black box warning on droperidol is not justified. 
  • Prophylaxis and treatment of the side-effects of neuraxial morphine analgesia following cesarean delivery. 
  • Randomized open-label phase II trial of 5-day aprepitant plus ondansetron compared to ondansetron alone in the prevention of chemotherapy-induced nausea-vomiting (CINV) in glioma patients receiving adjuvant temozolomide. 
  • Risk assessment of postoperative nausea and vomiting in the intravenous patient-controlled analgesia environment: predictive values of the Apfel's simplified risk score for identification of high-risk patients. 
  • Rolapitant for the prevention of postoperative nausea and vomiting: a prospective, double-blinded, placebo-controlled randomized trial. 
  • Safety of patients reason for FDA black box warning on droperidol. 
  • The effect of anti-emetic doses of dexamethasone on postoperative blood glucose levels in non-diabetic and diabetic patients: a prospective randomised controlled study. 
  • The effect of aprepitant and race on the pharmacokinetics of cyclophosphamide in breast cancer patients. 
  • The effectiveness of rescue antiemetics after failure of prophylaxis with ondansetron or droperidol: a preliminary report. 
  • The efficacy of the 5-HT3 receptor antagonists combined with droperidol for PONV prophylaxis is similar to their combination with dexamethasone. A meta-analysis of randomized controlled trials. 
  • The evaluation of drug rechallenge: the casopitant Phase III program. 
  • The impact of postoperative nausea and vomiting prophylaxis with dexamethasone on postoperative wound complications in patients undergoing laparotomy for endometrial cancer. 
  • The prevention of emesis in plastic surgery: a randomized, prospective study. 
  • The use of droperidol before and after the Food and Drug Administration black box warning: a survey of the members of the Society of Ambulatory Anesthesia. 
  • Transcutaneous acupoint electrical stimulation with the ReliefBand for the prevention of nausea and vomiting during and after cesarean delivery under spinal anesthesia. 
  • Vomiting following cataract surgery. 
  • Wound complications with dexamethasone for postoperative nausea and vomiting prophylaxis: a moot point? 
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  Keywords of People

  • Warner, David Samuel, Distinguished Distinguished Professor of Anesthesiology, in the School of Medicine, Neurobiology