Antiemetics

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  Subject Areas on Research

  • A comparison of ondansetron with promethazine for treating postoperative nausea and vomiting in patients who received prophylaxis with ondansetron: a retrospective database analysis. 
  • A comparison of the efficacy, safety, and patient satisfaction of ondansetron versus droperidol as antiemetics for elective outpatient surgical procedures. S3A-409 and S3A-410 Study Groups. 
  • A double-blind, placebo-controlled trial of four fixed rate infusion regimens of phenylephrine for hemodynamic support during spinal anesthesia for cesarean delivery. 
  • A phase I trial of olanzapine (Zyprexa) for the prevention of delayed emesis in cancer patients: a Hoosier Oncology Group study. 
  • A randomized comparison of a multimodal management strategy versus combination antiemetics for the prevention of postoperative nausea and vomiting. 
  • A randomized controlled comparison of electro-acupoint stimulation or ondansetron versus placebo for the prevention of postoperative nausea and vomiting. 
  • A randomized trial of phenylephrine infusion versus bolus dosing for nausea and vomiting during Cesarean delivery in obese women. 
  • A randomized, double-blind comparison of ondansetron versus placebo for prevention of nausea and vomiting after infratentorial craniotomy. 
  • A randomized, double-blind study to evaluate the efficacy and safety of three different doses of palonosetron versus placebo for preventing postoperative nausea and vomiting. 
  • A randomized, double-blind, close-ranging, pilot study of intravenous granisetron in the prevention of postoperative nausea and vomiting in patients abdominal hysterectomy. 
  • A randomized, double-blind, multicenter trial comparing transdermal scopolamine plus ondansetron to ondansetron alone for the prevention of postoperative nausea and vomiting in the outpatient setting. 
  • A randomized, double-blinded comparison of ondansetron, droperidol, and placebo for prevention of postoperative nausea and vomiting after supratentorial craniotomy. 
  • Adherence to antiemetic guidelines in patients with malignant glioma: a quality improvement project to translate evidence into practice. 
  • Algorithms for the prevention of postoperative nausea and vomiting: an efficacy and efficiency simulation. 
  • American Society of Clinical Oncology 2013 top five list in oncology. 
  • Analgesic and antiemetic needs following minimally invasive vs open staging for endometrial cancer. 
  • Anaphylactoid reaction due to the administration of ondansetron in a pediatric neurosurgical patient. 
  • Antiemetics added to phenylephrine infusion during cesarean delivery: a randomized controlled trial. 
  • Antiemetics: American Society of Clinical Oncology clinical practice guideline update. 
  • Appropriate Use of Antiemetics to Prevent Chemotherapy-Induced Nausea and Vomiting. 
  • Aprepitant for the Treatment of Chronic Refractory Pruritus. 
  • CON: Postoperative nausea and vomiting database research: limitations and opportunities. 
  • Cancer recurrence and hyperglycemia with dexamethasone for postoperative nausea and vomiting prophylaxis: more moot points? 
  • Chemotherapy-induced nausea and vomiting (CINV) and adherence to antiemetic guidelines: results of a survey of oncology nurses. 
  • Chemotherapy-induced nausea and vomiting. 
  • Children's coping strategies for chemotherapy-induced nausea and vomiting. 
  • Combination antiemetics: what is the evidence? 
  • Comment: Promethazine adverse events after implementation of a medication shortage interchange. 
  • Comparison of inhaled isopropyl alcohol and intravenous ondansetron for treatment of postoperative nausea. 
  • Comparison of postoperative nausea between benign and malignant brain tumor patients undergoing awake craniotomy: a retrospective analysis. 
  • Consensus guidelines for managing postoperative nausea and vomiting. 
  • Controlling emesis: evolving challenges, novel strategies. 
  • Cost-effectiveness of prophylactic antiemetic therapy with ondansetron, droperidol, or placebo. 
  • Current management of opioid-related side effects. 
  • Determination of plasma concentrations of propofol associated with 50% reduction in postoperative nausea. 
  • Dexamethasone for the prophylaxis of postoperative nausea and vomiting associated with neuraxial morphine administration: a systematic review and meta-analysis. 
  • Does midline shift predict postoperative nausea in brain tumor patients undergoing awake craniotomy? A retrospective analysis. 
  • Dolasetron for the prevention of postoperative nausea and vomiting following outpatient surgery with general anaesthesia: a randomized, placebo-controlled study. The Dolasetron PONV Prevention Study Group. 
  • Double-blind comparison of granisetron, promethazine, or a combination of both for the prevention of postoperative nausea and vomiting in females undergoing outpatient laparoscopies. 
  • Effects of high intraoperative inspired oxygen on postoperative nausea and vomiting in gynecologic laparoscopic surgery. 
  • Evidence-based management of postoperative nausea and vomiting: a review. 
  • Examining racial variation in antiemetic use and post-chemotherapy health care utilization for nausea and vomiting among breast cancer patients. 
  • Food and drug administration black box warning on the perioperative use of droperidol: a review of the cases. 
  • Gastrointestinal symptoms in cancer patients with advanced disease: new methodologies, insights, and a proposed approach. 
  • Haloperidol for postoperative nausea and vomiting: are we reinventing the wheel? 
  • Haloperidol plus ondansetron versus ondansetron alone for prophylaxis of postoperative nausea and vomiting. 
  • Haloperidol versus ondansetron for prophylaxis of postoperative nausea and vomiting. 
  • I.V. APD421 (amisulpride) prevents postoperative nausea and vomiting: a randomized, double-blind, placebo-controlled, multicentre trial. 
  • Impact of data by Fujii and colleagues on the meta-analysis of metoclopramide for antiemetic prophylaxis in women undergoing Caesarean delivery under neuraxial anaesthesia. 
  • Impact of intraoperative dexmedetomidine on postoperative analgesia following gynecologic surgery. 
  • Impact of postoperative nausea and vomiting prophylaxis with dexamethasone on the risk of recurrence of endometrial cancer. 
  • Improving Adherence to Evidence-Based Guidelines for Chemotherapy-Induced Nausea and Vomiting. 
  • Intraoperative colloid administration reduces postoperative nausea and vomiting and improves postoperative outcomes compared with crystalloid administration. 
  • Intravenous ondansetron in established postoperative emesis in children. S3A-381 Study Group. 
  • Long-acting serotonin antagonist (Palonosetron) and the NK-1 receptor antagonists: does extended duration of action improve efficacy? 
  • Low-dose naloxone infusion for the treatment of intractable nausea and vomiting after intrathecal morphine in a parturient. 
  • Management of postdischarge nausea and vomiting after ambulatory surgery. 
  • Metoclopramide for nausea and vomiting prophylaxis during and after Caesarean delivery: a systematic review and meta-analysis. 
  • Metoclopramide-induced tardive respiratory dyskinesia. 
  • Midazolam for Anxiolysis and Postoperative Nausea and Vomiting Prophylaxis: Can We Kill Two Birds with One Stone? 
  • Midazolam--an anti-emetic? 
  • Midtrimester abortion induced by serial intramuscular injections of 15(S)-15-methyl-prostaglandin F2alpha. 
  • Modification of the pharmacokinetics of high-dose cyclophosphamide and cisplatin by antiemetics. 
  • Ondansetron orally disintegrating tablet versus placebo for the prevention of postdischarge nausea and vomiting after ambulatory surgery. 
  • Patients' willingness to pay for anti-emetic treatment. 
  • Periprocedural outcomes comparing fibroid embolization and focused ultrasound: a randomized controlled trial and comprehensive cohort analysis. 
  • Pharmacology, pharmacogenetics, and clinical efficacy of 5-hydroxytryptamine type 3 receptor antagonists for postoperative nausea and vomiting. 
  • Pharmacotherapy of postoperative nausea and vomiting. 
  • Phase II study of docetaxel in advanced soft tissue sarcomas. 
  • Pilot study of aprepitant for prevention of post-ERCP pancreatitis in high risk patients: a phase II randomized, double-blind placebo controlled trial. 
  • Postoperative Pain Scores and Narcotic Use in Robotic-assisted Versus Laparoscopic Hysterectomy for Endometrial Cancer Staging. 
  • Postoperative blood sugars and use of starches - a reply. 
  • Postoperative hyperglycemia after 4- vs 8-10-mg dexamethasone for postoperative nausea and vomiting prophylaxis in patients with type II diabetes mellitus: a retrospective database analysis. 
  • Postoperative nausea and vomiting following inpatient surgeries in a teaching hospital: a retrospective database analysis. 
  • Postoperative nausea and vomiting--can it be eliminated? 
  • Preventing chemotherapy-induced nausea and vomiting with netupitant/palonosetron, the first fixed combination antiemetic: current and future perspective. 
  • Preventing postoperative nausea and vomiting: post hoc analysis of pooled data from two randomized active-controlled trials of aprepitant. 
  • Pro: The Food and Drug Administration Black box warning on droperidol is not justified. 
  • Prophylaxis and treatment of the side-effects of neuraxial morphine analgesia following cesarean delivery. 
  • Propofol and postoperative nausea and vomiting. 
  • Rolapitant for the prevention of postoperative nausea and vomiting: a prospective, double-blinded, placebo-controlled randomized trial. 
  • Safety of patients reason for FDA black box warning on droperidol. 
  • Selective serotonin 5-HT3 receptor antagonists for postoperative nausea and vomiting: are they all the same? 
  • Single-dose aprepitant vs ondansetron for the prevention of postoperative nausea and vomiting: a randomized, double-blind phase III trial in patients undergoing open abdominal surgery. 
  • The effect of anti-emetic doses of dexamethasone on postoperative blood glucose levels in non-diabetic and diabetic patients: a prospective randomised controlled study. 
  • The effect of aprepitant and race on the pharmacokinetics of cyclophosphamide in breast cancer patients. 
  • The effectiveness of rescue antiemetics after failure of prophylaxis with ondansetron or droperidol: a preliminary report. 
  • The efficacy of the 5-HT3 receptor antagonists combined with droperidol for PONV prophylaxis is similar to their combination with dexamethasone. A meta-analysis of randomized controlled trials. 
  • The evaluation of drug rechallenge: the casopitant Phase III program. 
  • The impact of postoperative nausea and vomiting prophylaxis with dexamethasone on postoperative wound complications in patients undergoing laparotomy for endometrial cancer. 
  • The prevention of emesis in plastic surgery: a randomized, prospective study. 
  • The use of droperidol before and after the Food and Drug Administration black box warning: a survey of the members of the Society of Ambulatory Anesthesia. 
  • Transcutaneous acupoint electrical stimulation with the ReliefBand for the prevention of nausea and vomiting during and after cesarean delivery under spinal anesthesia. 
  • Transcutaneous electrical nerve stimulation as an adjunct for controlling chemotherapy-induced nausea and vomiting in gynecologic oncology patients. 
  • Treatment of postoperative nausea and vomiting with single intravenous doses of dolasetron mesylate: a multicenter trial. Dolasetron Mesylate PONV Treatment Study Group. 
  • Vomiting following cataract surgery. 
  • Wound complications with dexamethasone for postoperative nausea and vomiting prophylaxis: a moot point? 
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  Keywords of People

  • Warner, David Samuel, Distinguished Professor of Anesthesiology, in the School of Medicine, Neurobiology