Antigens, Differentiation
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Subject Areas on Research
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A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress.
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Absence of phosphatidylinositol (PI)-linked proteins in a very early human multipotential haematopoietic marrow cell.
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Accelerated neural differentiation of mouse embryonic stem cells on aligned GYIGSR-functionalized nanofibers.
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Acidic stress promotes a glioma stem cell phenotype.
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Acute and chronic phagocyte determinants of cardiac allograft vasculopathy.
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Age-related studies of SIg, Leu-4 and concanavalin A receptor densities and capping in human lymphocytes.
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Alteration of the CD34+ Tf-1 beta cell line profile in response to long-term exposure to IL-15.
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Amplification of suppressor inducer pathway with monoclonal antibody, anti-2H4, identifying a novel epitope of the common leukocyte antigen/T200 antigen.
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Analysis of the biologic properties of p230 Bcr-Abl reveals unique and overlapping properties with the oncogenic p185 and p210 Bcr-Abl tyrosine kinases.
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Antibodies against the CD44 p80, lymphocyte homing receptor molecule augment human peripheral blood T cell activation.
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Antibodies to stem cell marker antigens reduce engraftment of hematopoietic stem cells.
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Apolipoprotein E4 stimulates cAMP response element-binding protein transcriptional activity through the extracellular signal-regulated kinase pathway.
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Association of Epstein-Barr virus with systemic lupus erythematosus: effect modification by race, age, and cytotoxic T lymphocyte-associated antigen 4 genotype.
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Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease.
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BMP4 is essential for lens induction in the mouse embryo.
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Bone marrow-derived progenitor cells contribute to experimental choroidal neovascularization.
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CD10/neutral endopeptidase 24.11 hydrolyzes bombesin-like peptides and regulates the growth of small cell carcinomas of the lung.
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CD19-dependent B lymphocyte signaling thresholds influence skin fibrosis and autoimmunity in the tight-skin mouse.
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CD34+CD38-lin- cord blood cells develop into dendritic cells in human thymic stromal monolayers and thymic nodules.
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CD44 antibody against In(Lu)-related p80, lymphocyte-homing receptor molecule inhibits the binding of human erythrocytes to T cells.
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CD44--a molecule involved in leukocyte adherence and T-cell activation.
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CD7+, CD4-, CD8- acute leukemia: a syndrome of malignant pluripotent lymphohematopoietic cells.
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CD8+ lymphocyte activation at human immunodeficiency virus type 1 seroconversion: development of HLA-DR+ CD38- CD8+ cells is associated with subsequent stable CD4+ cell levels. The Multicenter AIDS Cohort Study Group.
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CTLA-4 gene polymorphisms and systemic lupus erythematosus in a population-based study of whites and African-Americans in the southeastern United States.
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CTLA-4-Mediated inhibition of early events of T cell proliferation.
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CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates.
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Characteristics of the chemotactic activity of heparin cofactor II proteolysis products.
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Characterization of an Epstein-Barr virus receptor on human epithelial cells.
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Characterization of human thymic epithelial cell surface antigens: phenotypic similarity of thymic epithelial cells to epidermal keratinocytes.
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Characterization of neuronal/glial differentiation of murine adipose-derived adult stromal cells.
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Chondrogenic differentiation of human embryonic stem cell-derived cells in arginine-glycine-aspartate-modified hydrogels.
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Circulating natural killer cell phenotypes in men and women with major depression. Relation to cytotoxic activity and severity of depression.
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Clinicopathologic and cytogenic features of CD34 (My 10)-positive acute nonlymphocytic leukemia.
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Coevolution of the major histocompatibility complex and the t-complex in the mouse. I. Generation and maintenance of high complementarity associations.
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Complete and unidirectional conversion of human embryonic stem cells to trophoblast by BMP4.
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Con A-induced suppressor cell function depends on the activation of the CD4+CD45RA inducer T cell subpopulation.
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Control of cellular GADD34 levels by the 26S proteasome.
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Costimulator dependence of lymphokine secretion by naive and activated CD4+ T lymphocytes from TCR transgenic mice.
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Costimulatory molecules are active in the human xenoreactive T-cell response but not in natural killer-mediated cytotoxicity.
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Creation of tolerogenic human dendritic cells via intracellular CTLA4: a novel strategy with potential in clinical immunosuppression.
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Cytotoxic T lymphocyte antigen 4 (CTLA4) blockade accelerates the acute rejection of cardiac allografts in CD28-deficient mice: CTLA4 can function independently of CD28.
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Decreased suppressor-inducer T lymphocytes in multiple sclerosis and other neurological diseases.
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Detection of minimal residual T cell acute lymphoblastic leukemia by flow cytometry.
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Differential role for TLR3 in respiratory syncytial virus-induced chemokine expression.
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Disrupting the CD47-SIRPα anti-phagocytic axis by a humanized anti-CD47 antibody is an efficacious treatment for malignant pediatric brain tumors.
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Donor type natural killer cells after haploidentical T cell-depleted bone marrow stem cell transplantation in a patient with adenosine deaminase-deficient severe combined immunodeficiency.
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Down-regulation of growth arrest DNA damage-inducible gene 45beta expression is associated with human hepatocellular carcinoma.
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Early events in human T cell ontogeny. Phenotypic characterization and immunohistologic localization of T cell precursors in early human fetal tissues.
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Early-outgrowth of endothelial progenitor cells can function as antigen-presenting cells.
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Effects of IL-1 on hematopoietic progenitors after myelosuppressive chemoradiotherapy.
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Embryonic cellular organization: differential restriction of fates as revealed by cell aggregates and lineage markers.
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Essential amino acid deprivation induces monocytic differentiation of the human HL-60 myeloid leukemia cell line.
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Expression of protooncogene c-myb in normal human hematopoietic cells.
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Expression of the 67-kD laminin receptor, galectin-1, and galectin-3 in advanced human uterine adenocarcinoma.
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Expression, distribution, and biochemistry of human CD39. Role in activation-associated homotypic adhesion of lymphocytes.
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Fine mapping, gene content, comparative sequencing, and expression analyses support Ctla4 and Nramp1 as candidates for Idd5.1 and Idd5.2 in the nonobese diabetic mouse.
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Flow cytometric identification of intracellular antigens: detection of minimal residual leukemia.
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Genetic variants of GADD45A, GADD45B and MAPK14 predict platinum-based chemotherapy-induced toxicities in Chinese patients with non-small cell lung cancer.
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Glycosyl phosphatidylinositol-linked blood group antigens and paroxysmal nocturnal hemoglobinuria.
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Granulocyte-macrophage colony-stimulating factor and other cytokines regulate surface expression of the leukocyte adhesion molecule-1 on human neutrophils, monocytes, and their precursors.
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Growth arrest and DNA damage-inducible protein GADD34 assembles a novel signaling complex containing protein phosphatase 1 and inhibitor 1.
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Growth arrest and DNA damage-inducible protein GADD34 targets protein phosphatase 1 alpha to the endoplasmic reticulum and promotes dephosphorylation of the alpha subunit of eukaryotic translation initiation factor 2.
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Hierarchical Bayesian mixture modelling for antigen-specific T-cell subtyping in combinatorially encoded flow cytometry studies.
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IL-7 engages multiple mechanisms to overcome chronic viral infection and limit organ pathology.
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Immunohistologic analysis of the distribution of cell adhesion molecules within the inflammatory synovial microenvironment.
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Immunophenotypic characterization of sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease).
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Inducing unresponsiveness by the use of anti-CD3 immunotoxin, CTLA4-Ig, and anti-CD40 ligand.
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Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement.
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Influence of discrete and continuous culture conditions on human mesenchymal stem cell lineage choice in RGD concentration gradient hydrogels.
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Interaction of CTLA-4 with the clathrin-associated protein AP50 results in ligand-independent endocytosis that limits cell surface expression.
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Intravenous immunoglobulin G improves neurobehavioral and histological outcomes after traumatic brain injury in mice.
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Isolation of oligodendrocyte-like cells from human umbilical cord blood.
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LFA-1 binding site in ICAM-3 contains a conserved motif and non-contiguous amino acids.
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Mast cell modulation of the innate immune response to enterobacterial infection.
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Melanoma-specific cytotoxic T cells generated from peripheral blood lymphocytes. Implications of a renewable source of precursors for adoptive cellular immunotherapy.
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Molecular basis of T cell inactivation by CTLA-4.
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Multiparameter-fluorescence activated cell sorting analysis of retroviral vector gene transfer into primitive umbilical cord blood cells.
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Multisite comparison of methods for the quantitation of the surface expression of CD38 on CD8(+) T lymphocytes. The ACTG Advanced Flow Cytometry Focus Group.
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Multivalent RNA aptamers that inhibit CTLA-4 and enhance tumor immunity.
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Natural genetic variants influencing type 1 diabetes in humans and in the NOD mouse.
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Neurogenic differentiation of murine and human adipose-derived stromal cells.
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Non-erythroid effects of erythropoietin.
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PD-1-dependent mechanisms maintain peripheral tolerance of donor-reactive CD8+ T cells to transplanted tissue.
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PD-1/PD-L1, but not PD-1/PD-L2, interactions regulate the severity of experimental autoimmune encephalomyelitis.
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Phase 1 study in patients with metastatic melanoma of immunization with dendritic cells presenting epitopes derived from the melanoma-associated antigens MART-1 and gp100.
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Phenotype of infiltrating cells in an ex vivo model of human antiporcine hyperacute cardiac xenograft rejection.
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Photoreceptor synapses degenerate early in experimental choroidal neovascularization.
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Positively selected Leu-11a (CD16+) cells require the presence of accessory cells or factors for the lysis of herpes simplex virus-infected fibroblasts but not herpes simplex virus-infected Raji.
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Post-transcriptional regulation of antiviral gene expression by N6-methyladenosine.
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Prognostic factors in childhood T-cell acute lymphoblastic leukemia: a Pediatric Oncology Group study.
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Prognostic factors related to clinical response in patients with metastatic melanoma treated by CTL-associated antigen-4 blockade.
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Purification and partial characterization of a human hematopoietic precursor population.
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RNA-binding protein FXR2 regulates adult hippocampal neurogenesis by reducing Noggin expression.
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Regulation of B lymphocyte development and activation by the CD19/CD21/CD81/Leu 13 complex requires the cytoplasmic domain of CD19.
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Relationship of Inb antigen to other antigens on In(Lu)-related p80.
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Role of interleukin 12 and costimulators in T cell anergy in vivo.
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Synovial microenvironment-T cell interactions. Human T cells bind to fibroblast-like synovial cells in vitro.
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Systemic CTLA-4 blockade ameliorates glioma-induced changes to the CD4+ T cell compartment without affecting regulatory T-cell function.
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TLR agonists regulate PDGF-B production and cell proliferation through TGF-beta/type I IFN crosstalk.
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Technology evaluation: ipilimumab, Medarex/Bristol-Myers Squibb.
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The CD19 signal transduction complex of B lymphocytes. Deletion of the CD19 cytoplasmic domain alters signal transduction but not complex formation with TAPA-1 and Leu 13.
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The CD19/CD21 signal transducing complex of human B lymphocytes includes the target of antiproliferative antibody-1 and Leu-13 molecules.
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The CD19/CD21 signal transduction complex of B lymphocytes.
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The HB-6, CDw75, and CD76 differentiation antigens are unique cell-surface carbohydrate determinants generated by the beta-galactoside alpha 2,6-sialyltransferase.
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The PSA(-/lo) prostate cancer cell population harbors self-renewing long-term tumor-propagating cells that resist castration.
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The arrangement of the immunoglobulin-like domains of ICAM-1 and the binding sites for LFA-1 and rhinovirus.
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The role of adhesion molecules in epithelial-T-cell interactions in thymus and skin.
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The role of functionally distinct helper T lymphocyte subpopulations in the induction of human B cell differentiation.
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Thymocyte LFA-1 and thymic epithelial cell ICAM-1 molecules mediate binding of activated human thymocytes to thymic epithelial cells.
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Umbilical Cord Blood-Derived Mononuclear Cells Exhibit Pericyte-Like Phenotype and Support Network Formation of Endothelial Progenitor Cells In Vitro.
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Up-regulation of GRP78 and antiapoptotic signaling in murine peritoneal macrophages exposed to insulin.
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Update on anti-CTLA-4 antibodies in clinical trials.
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Keywords of People
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Erickson, Harold Paul,
Professor Emeritus of Cell Biology,
Cell Biology
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James, Michael Lucas,
Associate Professor of Anesthesiology,
Anesthesiology
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McLendon, Roger Edwin,
Professor of Pathology,
Pathology
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Sampson, John Howard,
Robert H., M.D. and Gloria Wilkins Professor of Neurosurgery, in the School of Medicine,
Biomedical Engineering
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Sunday, Mary Elizabeth Anne,
Professor of Pathology,
Cell Biology