Antigens, Differentiation, T-Lymphocyte
-
Subject Areas on Research
-
4,4'-Diisothiocyanatostilbene-2,2'-disulfonic acid inhibits CD3-T cell antigen receptor-stimulated Ca2+ influx in human T lymphocytes.
-
A monoclonal antibody reactive with a second epitope of the 67,000-dalton human T cell antigen.
-
A new nucleic acid-based agent inhibits cytotoxic T lymphocyte-mediated immune disorders.
-
A novel activation pathway for mature thymocytes. Costimulation of CD2 (T,p50) and CD28 (T,p44) induces autocrine interleukin 2/interleukin 2 receptor-mediated cell proliferation.
-
AD2, a human molecule involved in the interaction of T cells with epidermal keratinocytes and thymic epithelial cells.
-
Abnormalities of circulating T-cell subpopulations in patients with cutaneous T-cell lymphoma: cutaneous lymphocyte-associated antigen expression on T cells correlates with extent of disease.
-
Access of HIV-2 to CD169-dependent dendritic cell-mediated trans infection pathway is attenuated.
-
Activation of decidual invariant natural killer T cells promotes lipopolysaccharide-induced preterm birth.
-
Analysis of T-cell differentiation antigens in acute lymphatic leukemia using monoclonal antibodies.
-
Analysis of clones derived from human CD7+CD4-CD8-CD3- thymocytes.
-
Analysis of expression of CD2, CD3, and T cell antigen receptor molecules during early human fetal thymic development.
-
Antibodies against the CD44 p80, lymphocyte homing receptor molecule augment human peripheral blood T cell activation.
-
Antibody valence and induced signal transduction: the role of antibody valence in anti-CD3-induced signal transduction in isolated normal T cells.
-
Antithymocyte globulin stimulates human hematopoietic progenitor cells.
-
BAFF is increased in renal transplant patients following treatment with alemtuzumab.
-
Binding site for human immunodeficiency virus coat protein gp120 is located in the NH2-terminal region of T4 (CD4) and requires the intact variable-region-like domain.
-
Bromelain treatment of human T cells removes CD44, CD45RA, E2/MIC2, CD6, CD7, CD8, and Leu 8/LAM1 surface molecules and markedly enhances CD2-mediated T cell activation.
-
CD4+Thy1- thymocytes with a Th-type 2 cytokine response.
-
CD4-independent binding of HIV-1 to the B lymphocyte receptor CR2 (CD21) in the presence of complement and antibody.
-
CD44 antibody against In(Lu)-related p80, lymphocyte-homing receptor molecule inhibits the binding of human erythrocytes to T cells.
-
CD6-ligand interactions: a paradigm for SRCR domain function?
-
CD6.
-
CD68/CD31 immunohistochemistry double stain demonstrates increased accuracy in diagnosing pathologic antibody-mediated rejection in cardiac transplant patients.
-
CD69 gene is differentially regulated in T and B cells by evolutionarily conserved promoter-distal elements.
-
Characterization of a CD6 ligand(s) expressed on human- and murine-derived cell lines and murine lymphoid tissues.
-
Characterization of effector T cells in dry eye disease.
-
Characterization of human CD7 transgenic mice.
-
Characterization of renal neoplasms with monoclonal antibodies to leukocyte differentiation antigens.
-
Characterization of the surface topography and putative tertiary structure of the human CD7 molecule.
-
Cloning of murine splenic T lymphocytes and natural killer (NK) cells on filter paper discs: detection of a novel NK/T phenotype.
-
Cloning, mapping, and characterization of activated leukocyte-cell adhesion molecule (ALCAM), a CD6 ligand.
-
Combined chemoseparation and immunoseparation of clonogenic T lymphoma cells from human bone marrow using 2'-deoxycoformycin, deoxyadenosine, 3A1 monoclonal antibody, and complement.
-
Correlations of unique clinical, immunotypic, and histologic findings in cutaneous gamma/delta T-cell lymphoma.
-
Cytochalasins enhance the proliferation of CD4 cells through the CD3-Ti antigen receptor complex or the CD2 molecule through an effect on early events of activation.
-
Demonstration of phenotypic abnormalities of thymic epithelium in thymoma including two cases with abundant Langerhans cells.
-
Differential reconstitution of T cell subsets following immunodepleting treatment with alemtuzumab (anti-CD52 monoclonal antibody) in patients with relapsing-remitting multiple sclerosis.
-
Differentiation of human T cells.
-
Donor type natural killer cells after haploidentical T cell-depleted bone marrow stem cell transplantation in a patient with adenosine deaminase-deficient severe combined immunodeficiency.
-
Early B-cell activation after West Nile virus infection requires alpha/beta interferon but not antigen receptor signaling.
-
Early events in human T cell ontogeny. Phenotypic characterization and immunohistologic localization of T cell precursors in early human fetal tissues.
-
Effect of thymectomy on peripheral lymphocyte subsets in myasthenia gravis: selective effect on T-cells in patients with thymic atrophy.
-
Electron transport complex I is required for CD8+ T cell function.
-
Endocytosis and recycling of the T3-T cell receptor complex. The role of T3 phosphorylation.
-
Enhanced T cell responses due to diacylglycerol kinase zeta deficiency.
-
Enumerating antigen-specific T-cell responses in peripheral blood: a comparison of peptide MHC Tetramer, ELISpot, and intracellular cytokine analysis.
-
Epstein-Barr virus-negative diffuse large B cell lymphoma with aberrant expression of CD3 and other T cell-associated antigens: report of three cases with a review of the literature.
-
Evaluation of lymphocyte differentiation in primary and secondary immunodeficiency diseases.
-
Expression of cell-adhesion molecules in the salivary gland microenvironment of Sjögren's syndrome.
-
Expression of differentiation antigens by hybrids of human lymphoblastoid cells.
-
Expression of early activation antigen (CD69) during human thymic development.
-
Expression profiling of a transformed thymocyte cell line undergoing maturation in vitro identifies multiple genes involved in positive selection.
-
Fine mapping, gene content, comparative sequencing, and expression analyses support Ctla4 and Nramp1 as candidates for Idd5.1 and Idd5.2 in the nonobese diabetic mouse.
-
Function of the LFA-1 and T4 molecules in the direct activation of resting human B lymphocytes by T lymphocytes.
-
Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line.
-
Granulysin is a key mediator for disseminated keratinocyte death in Stevens-Johnson syndrome and toxic epidermal necrolysis.
-
HIV-1 GP120-mediated immune suppression and lymphocyte destruction in the absence of viral infection.
-
HLA class II molecules on monocytes regulate T cell proliferation through physical interaction in the CD3 activation pathway.
-
Human T cell antigen expression during the early stages of fetal thymic maturation.
-
Human T cell receptor-gamma and -delta chain pairing analyzed by transfection of a T cell receptor-delta negative mutant cell line.
-
Human T-cell lymphotropic virus IIIB glycoprotein (gp120) bound to CD4 determinants on normal lymphocytes and expressed by infected cells serves as target for immune attack.
-
Human immunodeficiency virus-1 disease progression in hemophiliacs.
-
Human lymphocyte differentiation antigens HB-10 and HB-11. I. Ontogeny of antigen expression.
-
Human lymphocyte differentiation antigens HB-10 and HB-11. II. Differential production of B cell growth and differentiation factors by distinct helper T cell subpopulations.
-
Human medullary thymocyte p80 antigen and In(Lu)-related p80 antigen reside on the same protein.
-
Human postnatal CD4- CD8- CD3- thymic T cell precursors differentiate in vitro into T cell receptor delta-bearing cells.
-
Human thymic epithelial cells directly induce activation of autologous immature thymocytes.
-
Human thymic epithelial cells produce IL-6, granulocyte-monocyte-CSF, and leukemia inhibitory factor.
-
Human thymocytes bind to autologous and allogeneic thymic epithelial cells in vitro.
-
Identification and characterization of a 100-kD ligand for CD6 on human thymic epithelial cells.
-
Immunomodulation of human CD8⁺ T cells by thymoglobulin in vitro.
-
Immunosuppressive effects of subglutinol derivatives.
-
In situ studies of the germinal center reaction.
-
In vitro and in vivo human T cell repertoire in kidney allograft rejection.
-
In vitro autoantibody production by normal adult and cord blood B cells.
-
Induction of T cell CD7 gene transcription by nonmitogenic ionomycin-induced transmembrane calcium flux.
-
Inhibition of murine cytotoxic T lymphocyte activity by a synthetic retroviral peptide and abrogation of this activity by IL.
-
Innate-like Gene Expression of Lung-Resident Memory CD8+ T Cells during Experimental Human Influenza: A Clinical Study.
-
Interaction between the human T-cell lymphotropic virus type IIIB envelope glycoprotein gp120 and the surface antigen CD4: role of carbohydrate in binding and cell fusion.
-
Interleukin-15 enhances the secretion of IFN-gamma and CC chemokines by natural killer cells from HIV viremic and aviremic patients.
-
Isolation and characterization of the genomic human CD7 gene: structural similarity with the murine Thy-1 gene.
-
L-selectin ligands expressed by human leukocytes are HECA-452 antibody-defined carbohydrate epitopes preferentially displayed by P-selectin glycoprotein ligand-1.
-
LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway.
-
Leukemias and lymphomas of thymic differentiation.
-
Ligand binding to the LFA-3 cell adhesion molecule induces IL-1 production by human thymic epithelial cells.
-
Long-term outcomes of nonconditioned patients with severe combined immunodeficiency transplanted with HLA-identical or haploidentical bone marrow depleted of T cells with anti-CD6 mAb.
-
Loss of DNAM-1 contributes to CD8+ T-cell exhaustion in chronic HIV-1 infection.
-
Monoclonal antibodies to CD2 and lymphocyte function-associated antigen 3 inhibit human thymic epithelial cell-dependent mature thymocyte activation.
-
Monoclonal antibodies to tissue-associated antigens as antitumor reagents.
-
Monoclonal antibody OKT3-induced T cell proliferation: differential role of HLA class II determinants expressed by T cells and monocytes.
-
Monoclonal antibody defines human cell surface protein p80 on intrathymic T cells.
-
NKG2D-mediated signaling requires a DAP10-bound Grb2-Vav1 intermediate and phosphatidylinositol-3-kinase in human natural killer cells.
-
Natural genetic variants influencing type 1 diabetes in humans and in the NOD mouse.
-
Nicotinamide adenine dinucleotide (NAD) and its metabolites inhibit T lymphocyte proliferation: role of cell surface NAD glycohydrolase and pyrophosphatase activities.
-
OKT3 vs ALG induction therapy in combined pancreas-kidney transplantation.
-
Ontogeny of T-cell precursors: a model for the initial stages of human T-cell development.
-
Ontogeny of the human thymus during fetal development.
-
Phenotypic and functional characterization of human malignant T cells.
-
Purified lymphocyte function-associated antigen-3 (LFA-3) activates human thymocytes via the CD2 pathway.
-
Quality control in the flow cytometric measurement of T-lymphocyte subsets: the multicenter AIDS cohort study experience. The Multicenter AIDS Cohort Study Group.
-
Regulation of T cell receptor-induced activation of the Ras-ERK pathway by diacylglycerol kinase zeta.
-
Regulation of leukocyte migration by activation of the leukocyte adhesion molecule-1 (LAM-1) selectin.
-
Regulation of the tyrosine kinase-dependent adhesion pathway in human lymphocytes through CD45.
-
Relationships among renal allograft biopsy infiltrates, growth of T cell lines, and irreversible rejection.
-
Role of protein N-glycosylation in pathogenesis of human immunodeficiency virus type 1.
-
Selective antiviral activity of synthetic soluble L-tyrosine and L-dopa melanins against human immunodeficiency virus in vitro.
-
Selective modulation of human natural killer cells in vivo after prolonged infusion of low dose recombinant interleukin 2.
-
Skin-resident T cells sense ultraviolet radiation-induced injury and contribute to DNA repair.
-
Syn-capping of human T lymphocyte adhesion/activation molecules and their redistribution during interaction with endothelial cells.
-
T cell CD7 mRNA expression is regulated by both transcriptional and post-transcriptional mechanisms.
-
T cell receptor gamma/delta expression on lymphocyte populations of breast cancer patients.
-
T lymphocyte depletion of human peripheral blood and bone marrow using monoclonal antibodies and magnetic microspheres.
-
T-cell receptors of human suppressor cells.
-
T3 glycoprotein is functional although structurally distinct on human T-cell receptor gamma T lymphocytes.
-
The Lutheran glycoprotein: a multifunctional adhesion receptor.
-
The cutaneous lymphocyte antigen is an essential component of the L-selectin ligand induced on human vascular endothelial cells.
-
The effects of donor-specific blood transfusion enhancement of rat renal allografts on cytotoxic activity and phenotypes of peripheral blood lymphocytes, splenocytes, and graft-infiltrating cells.
-
The regulation of T-cell cytokine production by ICOS-B7H2 interactions at the human fetomaternal interface.
-
The role for interleukin-12 therapy of cutaneous T cell lymphoma.
-
The role of the L3T4 molecule in mitogen and antigen-activated signal transduction.
-
Thymocyte binding to human thymic epithelial cells is inhibited by monoclonal antibodies to CD-2 and LFA-3 antigens.
-
Transient CD86 expression on hepatitis C virus-specific CD8+ T cells in acute infection is linked to sufficient IL-2 signaling.
-
Two forms of the T-cell receptor gamma protein found on peripheral blood cytotoxic T lymphocytes.
-
Keywords of People
-
Ferrari, Guido,
Professor in Surgery,
Molecular Genetics and Microbiology
-
Schanberg, Laura Eve,
Professor of Pediatrics,
Pediatrics, Rheumatology
-
Weinhold, Kent James,
Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery,
Integrative Immunobiology