Antimetabolites
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Subject Areas on Research
- A novel mouse model of podocyte depletion.
- A promising approach for treatment of tumor-induced bone diseases: utilizing bisphosphonate derivatives of nucleoside antimetabolites.
- Augmenting podocyte injury promotes advanced diabetic kidney disease in Akita mice.
- Carbon monoxide reversibly alters iron homeostasis and respiratory epithelial cell function.
- Cell-cell interactions and bronchoconstrictor eicosanoid reduction with inhaled carbon monoxide and resolvin D1.
- Consequences of unilateral hearing loss: cortical adjustment to unilateral deprivation.
- Crystal structures of Toxoplasma gondii uracil phosphoribosyltransferase reveal the atomic basis of pyrimidine discrimination and prodrug binding.
- Cytochalasins induce actin polymerization in human leukocytes.
- Development of long-distance efferent projections from fetal hippocampal grafts depends upon pathway specificity and graft location in kainate-lesioned adult hippocampus.
- Effect of inhibitors of proteolytic enzymes on the growth of normal and polyoma transformed BHK cells.
- Enduring consequences of early-life infection on glial and neural cell genesis within cognitive regions of the brain.
- Genome-scale analysis of anti-metabolite directed strain engineering.
- Hepatic sulfite oxidase. Identification of the molybdenum center as the site of irreversible inactivation by ferricyanide.
- Hos2p/Set3p deacetylase complex signals secretory stress through the Mpk1p cell integrity pathway.
- Increase in intracellular free calcium concentration of Limulus photoreceptors caused by a metabolic inhibitor.
- Inhibiting glycolysis to reduce seizures: how it might work.
- Intravitreal sustained release corticosteroid-5-fluoruracil conjugate in the treatment of experimental proliferative vitreoretinopathy.
- Long-term intersession variability for single-breath diffusing capacity.
- Long-term stabilization of vein graft wall architecture and prolonged resistance to experimental atherosclerosis after E2F decoy oligonucleotide gene therapy.
- Lysophosphatidic acid stimulates neurotransmitter-like conductance changes that precede GABA and L-glutamate in early, presumptive cortical neuroblasts.
- Macrophage depletion diminishes lesion size and severity in experimental choroidal neovascularization.
- Metabolic inhibition-induced transient Ca2+ increase depends on mitochondria in a human proximal renal cell line.
- Metabolic requirements of contractile force generation in platelet rich plasma - a rheological study.
- NIH conference. Pathophysiology of immune hemolytic anemia.
- Pharmacogenomics in pediatric rheumatology.
- Pleural dosimetry and pathobiological responses in rats and hamsters exposed subchronically to MMVF 10a fiberglass.
- Preferential accumulation of antigen-specific effector CD4 T cells at an antigen injection site involves CD62E-dependent migration but not local proliferation.
- Prevention of acute lung injury in swine: depletion of pulmonary intravascular macrophages using liposomal clodronate.
- Protein kinase-zeta interacts with munc18c: role in GLUT4 trafficking.
- Regional metabolic changes in the pedunculopontine nucleus of unilateral 6-hydroxydopamine Parkinson's model rats.
- Regulation of endothelial cell prostaglandin synthesis by glutathione.
- Role of macrophages in the generation of circulating blood nucleosomes from dead and dying cells.
- Sonic hedgehog is an autocrine viability factor for myofibroblastic hepatic stellate cells.
- Swainsonine protects both murine and human haematopoietic systems from chemotherapeutic toxicity.
- The CO/HO system reverses inhibition of mitochondrial biogenesis and prevents murine doxorubicin cardiomyopathy.
- The role of calcium ions in the suppression of the photoresponse during anoxia and application of metabolic inhibitors.
- Treatment of juvenile idiopathic arthritis-associated uveitis: challenges and update.
- Using pharmacogenetics to improve drug safety and efficacy.
- Vasoactive intestinal peptide, forskolin, and genistein increase apical CFTR trafficking in the rectal gland of the spiny dogfish, Squalus acanthias. Acute regulation of CFTR trafficking in an intact epithelium.