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Subject Areas on Research
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A Phase I study of active immunotherapy with carcinoembryonic antigen peptide (CAP-1)-pulsed, autologous human cultured dendritic cells in patients with metastatic malignancies expressing carcinoembryonic antigen.
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A defect in the humoral immune response to protein antigens and haptens in immunoglobulin mu heavy-chain transgenic mice.
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A potentially abundant junctional RNA motif stabilized by m6A and Mg2.
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A role for immunogenic DNA in the pathogenesis of systemic lupus erythematosus.
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A simple enzyme-linked immunosorbent assay for antibodies to native DNA.
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A subgroup of murine monoclonal anti-deoxyribonucleic acid antibodies traverse the cytoplasm and enter the nucleus in a time-and temperature- dependent manner.
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ANA as an entry criterion for the classification of SLE.
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Altered T-dependent antigen responses and development of autoimmune symptoms in mice lacking E2A in T lymphocytes.
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An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1.
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Anti-DNA and autoantibodies.
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Anti-DNA antibodies form immune deposits at distinct glomerular and vascular sites.
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Anti-DNA antibodies in systemic lupus erythematosus.
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Anti-DNA antibodies in systemic lupus erythematosus: a case of mistaken identity?
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Anti-DNA antibodies--quintessential biomarkers of SLE.
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Anti-La antibodies.
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Anti-Ro and anti-nRNP response in unaffected family members of SLE patients.
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Antibodies against retroviral proteins and nuclear antigens in a subset of idiopathic CD4+ T lymphocytopenia patients.
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Antibodies to DNA. A perspective.
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Antibodies to DNA: infection or genetics?
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Anticardiolipin antibodies in unselected pregnant women. Relationship to fetal outcome.
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Anticentromere antibody. Clinical Correlations and association with favorable prognosis in patients with scleroderma variants.
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Antidouble stranded DNA antibody assays in systemic lupus erythematosus: correlations of longitudinal antibody measurements.
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Antinuclear antibodies and nuclear antigens in NZB myeloma ascitic fluids.
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Antinuclear antibodies in healthy people: the tip of autoimmunity's iceberg?
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Antinuclear antibodies in rheumatic disease: a proposal for a function-based classification.
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Antinuclear antibody testing - misunderstood or misbegotten?
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Assay variation in the detection of antinuclear antibodies in the sera of patients with established SLE.
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Autoantibodies and their idiotypes.
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Autoantibodies and their significance.
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Autoantibodies before the clinical onset of systemic lupus erythematosus.
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Autoantibodies to Dense Fine Speckles in Pediatric Diseases and Controls.
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Autoantibody levels in myositis patients correlate with clinical response during B cell depletion with rituximab.
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Autoimmunity: the nuclear arsenal of autoimmunity.
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B lymphocytes and systemic lupus erythematosus.
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Brief Report: HLA-DRB1, DQA1, and DQB1 in Juvenile-Onset Systemic Sclerosis.
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Catastrophic antiphospholipid syndrome with concurrent thrombotic and hemorrhagic manifestations.
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Cellular requirements for anti-DNA production induced in mice by immunization with bacterial DNA.
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Characterization and comparison of commercially available antinuclear antibody kits using single pattern index sera.
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Characterization of monoclonal antibodies with specificity for DNA and the synthetic polypeptide antigen (T,G)-A-L.
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Clinical problem-solving. Taken out of context.
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Comparison of an enzyme immunoassay to an indirect fluorescent immunoassay for the detection of antinuclear antibodies.
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Complement C4 inhibits systemic autoimmunity through a mechanism independent of complement receptors CR1 and CR2.
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Curiouser and curiouser: the role(s) of AID expression in self-tolerance.
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DNA as a marker of cell death in systemic lupus erythematosus.
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Defects in mononuclear phagocytic system (MPS) function in autoimmune MRL-lpr/lpr mice.
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Deficient expression of antibodies specific for bacterial DNA by patients with systemic lupus erythematosus.
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Development of autoantibodies before the clinical onset of systemic lupus erythematosus.
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Differences in V kappa gene utilization and VH CDR3 sequence among anti-DNA from C3H-lpr mice and lupus mice with nephritis.
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Discrimination of antineutrophil antibodies from antinuclear antibodies using immunofluorescence on neutrophils and HL60 cells.
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Diverse endogenous light chains contribute to basement membrane reactivity in nonautoimmune mice transgenic for an anti-laminin Ig heavy chain.
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Early events in lupus humoral autoimmunity suggest initiation through molecular mimicry.
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Effect of sex on the induction of anti-DNA antibodies in normal mice immunized with bacterial DNA.
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Etanercept-induced lupus-like syndrome in a patient with rheumatoid arthritis.
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Evolving story of autoantibodies in systemic lupus erythematosus.
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Exposure of mice to topical bovine thrombin induces systemic autoimmunity.
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Expression of a highly conserved anti-DNA idiotype in normal and autoimmune mice.
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Fatal lupus pleuritis presenting in pregnancy. A case report.
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Frequency of abnormal hand and wrist radiographs at time of diagnosis of polyarticular juvenile rheumatoid arthritis.
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Gamma delta T cell help of B cells is induced by repeated parasitic infection, in the absence of other T cells.
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Genetic control of inflammatory arthritis and glomerulonephritis in congenic lpr mice and their F1 hybrids.
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Genetic control of inflammatory arthritis in congenic lpr mice.
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Hybridoma SLE autoantibodies: insights for the pathogenesis of autoimmune disease.
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IgG binding of monoclonal anti-nuclear antibodies from MRL-lpr/lpr mice.
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Immune activation by bacterial DNA: a new genetic code.
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Immune phenotypes in individuals positive for antinuclear antibodies: The impact of race and ethnicity.
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Immune recognition of DNA in SLE.
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Immune response to DNA in systemic lupus erythematosus.
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Immune responses to DNA in normal and aberrant immunity.
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Immunization with the Sm nuclear antigen induces anti-Sm antibodies in normal and MRL mice.
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Immunochemical properties of anti-DNA antibodies in the sera of patients with Escherichia coli bacteremia.
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Immunological properties of bacterial DNA.
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In vitro and in vivo expression of a nephritogenic Ig heavy chain determinant: pathogenic autoreactivity requires permissive light chains.
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In vitro autoantibody production by normal adult and cord blood B cells.
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Independent expression of autoantibodies in systemic lupus erythematosus.
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Independently derived murine glomerular immune deposit-forming anti-DNA antibodies are encoded by near-identical VH gene sequences.
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Induction of anti-double stranded DNA antibodies in normal mice by immunization with bacterial DNA.
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Induction of immune-mediated glomerulonephritis in normal mice immunized with bacterial DNA.
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Inhibition of in vitro NZB antibody responses by cyclosporine.
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Liposarcoma presenting as an intraluminal ureteral mass.
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Lupus-like nephrotropic autoantibodies in non-autoimmune mice harboring an anti-basement membrane/anti-DNA Ig heavy chain transgene.
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Lymphocytic lymphoma and systemic lupus erythematosus: their coexistence with antibody to the Sm antigen.
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Maternal autoantibody levels in congenital heart block and potential prophylaxis with antiinflammatory agents.
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Mechanisms of anti-DNA antibody expression in normal and aberrant immunity.
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Mechanisms of antinuclear antibody production in the rheumatic diseases.
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Mice lacking the p53-effector gene Gadd45a develop a lupus-like syndrome.
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Microparticles as a source of extracellular DNA.
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Microparticles as antigenic targets of antibodies to DNA and nucleosomes in systemic lupus erythematosus.
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Microparticles as autoadjuvants in the pathogenesis of SLE.
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Molecular analysis of spontaneous nephrotropic anti-laminin antibodies in an autoimmune MRL-lpr/lpr mouse.
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Molecular and structural analysis of nuclear localizing anti-DNA lupus antibodies.
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Molecular characterization of anti-DNA antibodies induced in normal mice by immunization with bacterial DNA. Differences from spontaneous anti-DNA in the content and location of VH CDR3 arginines.
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Molecular properties of anti-DNA induced in preautoimmune NZB/W mice by immunization with bacterial DNA.
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Murine monoclonal anti-DNA antibodies penetrate cells, bind to nuclei, and induce glomerular proliferation and proteinuria in vivo.
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Mycophenolate mofetil suppresses autoimmunity and mortality in the female NZB x NZW F1 mouse model of systemic lupus erythematosus.
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Neuroendocrine response to cold in Raynaud's syndrome.
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New Perspectives in Rheumatology: Biomarkers as Entry Criteria for Clinical Trials of New Therapies for Systemic Lupus Erythematosus: The Example of Antinuclear Antibodies and Anti-DNA.
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New insights into the role of antinuclear antibodies in systemic lupus erythematosus.
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One hundred anti-Ro (SS-A) antibody positive patients: a 10-year follow-up.
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Ophthalmologic examinations in children with juvenile rheumatoid arthritis.
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Patterns of autoantibody expression in pediatric and adult systemic lupus erythematosus.
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Polyspecific binding of Escherichia coli beta-galactosidase by murine antibodies to DNA.
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Practice-based differences in paediatric discoid lupus erythematosus.
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Prediction of disease relapse in a cohort of paediatric patients with localized scleroderma.
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Prediction of outcome in fetal autoimmune complete heart block.
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Preliminary criteria for global flares in childhood-onset systemic lupus erythematosus.
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Prognostic marker analysis in pediatric intracranial ependymomas.
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Recovery of B-cell homeostasis after rituximab in chronic graft-versus-host disease.
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Regulatory B cells (B10 cells) have a suppressive role in murine lupus: CD19 and B10 cell deficiency exacerbates systemic autoimmunity.
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Reply to: Diagnostic role of anti-dsDNA antibodies: do not forget autoimmune hepatitis.
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Response to 'Antinuclear antibodies by indirect immunofluorescence and solid phase assays' by Bossuyt et al.
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Response to: "Antinuclear autoantibodies: discordance among four different assays" by Pacheco et al.
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Response to: 'ANA testing in "real life"' by Infantino etal.
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Response to: 'Antinuclear antibody as entry criterion for classification of systemic lupus erythematosus: pitfalls and opportunities' by Bossuyt et al.
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Response to: 'Can solid-phase assays replace immunofluorescence for ANA screening?' by Bizzaro.
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Response to: 'Lack of standardization of ANA and implications for drug development and precision medicine' by Mahler.
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Response to: 'Pitfalls of antinuclear antibody detection in systemic lupus erythematosus: the positive experience of a national multi-center study' by Pregnalato et al.
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Response to: 'Unending story of the indirect immunofluorescence assay on HEp-2 cells: old problems and new solutions?' by Meroni et al.
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Response to: 'Variation in antinuclear antibody detection by automated indirect immunofluorescence analysis' by van Hoovels et al.
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Role of ANA testing in the classification of patients with systemic lupus erythematosus.
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Role of Antinuclear Antibody Determinations in Classification Criteria for Systemic Lupus Erythematosus: Comment on the Article by Leuchten et al.
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Safety and immunogenicity of a fully glycosylated recombinant gp160 human immunodeficiency virus type 1 vaccine in subjects at low risk of infection. National Institute of Allergy and Infectious Diseases AIDS Vaccine Evaluation Group Network.
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Scavenging nucleic acid debris to combat autoimmunity and infectious disease.
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Selective recognition of DNA antigenic determinants by murine monoclonal anti-DNA antibodies.
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Serum immunoglobulin levels in systemic lupus erythematosus: the effects of age, sex, race and disease duration.
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Specificity analysis of monoclonal anti-DNA antibodies.
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Specificity and idiotypic analysis of a monoclonal anti-Sm antibody with anti-DNA activity.
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Specificity and immunochemical properties of anti-DNA antibodies induced in normal mice by immunization with mammalian DNA with a CpG oligonucleotide as adjuvant.
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Specificity and immunochemical properties of antibodies to bacterial DNA.
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Specificity of anti-DNA antibodies induced in normal mice by immunization with bacterial DNA.
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Specificity of autoantibodies for recombinant 60-kd and 52-kd Ro autoantigens.
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Spontaneous expression of antibodies to DNA of various species origin in sera of normal subjects and patients with systemic lupus erythematosus.
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Standardization of anti-DNA antibody assays.
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Structural features of nephritogenic lupus autoantibodies.
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Structural properties of a subset of nephritogenic anti-DNA antibodies.
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Suppression of renal disease and mortality in the female NZB x NZW F1 mouse model of systemic lupus erythematosus (SLE) by chenodeoxycholic acid.
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Sweet syndrome associated with hydralazine-induced lupus erythematosus.
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Systemic lupus erythematosus and related diseases.
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Systemic lupus erythematosus.
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Systemic lupus erythematosus. Diagnosis and treatment.
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Temporal correlation of antibody responses to different epitopes of the human La autoantigen.
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The B-cell repertoire for autoantibodies: frequency of precursor cells for anti-DNA antibodies.
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The Binding Mechanisms of Antibodies to DNA from Healthy Subjects and Patients with Systemic Lupus Erythematosus: The Role of Monogamous Bivalency and Fc Dependence.
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The Interaction of Anti-DNA Antibodies with DNA: Evidence for Unconventional Binding Mechanisms.
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The Role of Cell Death in the Pathogenesis of SLE: Is Pyroptosis the Missing Link?
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The Use of Poly-L-Lysine as a Capture Agent to Enhance the Detection of Antinuclear Antibodies by ELISA.
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The anti-La response of a single MRL/Mp-lpr/lpr mouse: specificity for DNA and VH gene usage.
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The antibody response of normal mice to immunization with single-stranded DNA of various species origin.
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The antigenic properties of bacterial DNA in normal and aberrant immunity.
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The binding of SLE autoantibodies to mitochondria.
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The binding of anti-DNA antibodies to phosphorothioate oligonucleotides in a solid phase immunoassay.
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The complex role of DNA, histones and HMGB1 in the pathogenesis of SLE.
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The effect of polyamines on the binding of anti-DNA antibodies from patients with SLE and normal human subjects.
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The fine specificity of monoclonal anti-DNA antibodies induced in normal mice by immunization with bacterial DNA.
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The immunologic properties of DNA.
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The influence of DNA size on the binding of anti-DNA antibodies in the solid and fluid phase.
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The influence of DNA size on the binding of antibodies to DNA in the sera of normal human subjects and patients with systemic lupus erythematosus (SLE).
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The influence of Yaa on anti-DNA responses of B6-lpr mice.
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The influence of the lpr gene on B cell activation: differential antibody expression in lpr congenic mouse strains.
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The influence of variable-region somatic mutations on the specificity and pathogenicity of murine monoclonal anti-DNA antibodies.
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The inhibition of anti-DNA binding to DNA by nucleic acid binding polymers.
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The interaction of anti-DNA antibodies with DNA antigen: Evidence for hysteresis for high avidity binding.
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The mechanism of autoantibody production in an autoimmune MRL/lpr mouse.
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The prevention, screening and treatment of congenital heart block from neonatal lupus: a survey of provider practices.
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The relationship between soluble interleukin 2 receptor levels and antidouble stranded DNA antibody levels in patients with systemic lupus erythematosus.
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The relationship of anticardiolipin antibodies to disease manifestations in pediatric systemic lupus erythematosus.
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The role of bacterial DNA in autoantibody induction.
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The role of cpg sequences in the induction of anti-DNA antibodies.
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The role of extracellular DNA in autoimmunity in SLE.
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The role of innate immunity in the induction of autoimmunity.
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The role of microparticles in the generation of immune complexes in murine lupus.
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The role of monogamous bivalency and Fc interactions in the binding of anti-DNA antibodies to DNA antigen.
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The use of fluorometric assays to assess the immune response to DNA in murine systemic lupus erythematosus.
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Thromboxane receptor blockade reduces renal injury in murine lupus nephritis.
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Tumor necrosis factor alpha blockers and the induction of anti-DNA autoantibodies.
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VH gene analysis of spontaneously activated B cells in adult MRL-lpr/lpr mice. J558 bias is not limited to classic lupus autoantibodies.
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Variability in Antinuclear Antibody Testing to Assess Patient Eligibility for Clinical Trials of Novel Treatments for Systemic Lupus Erythematosus.
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Keywords of People