Antioxidants

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  Subject Areas on Research

  • A Redox-active Mn Porphyrin, MnTnBuOE-2-PyP5+, Synergizes with Carboplatin in Treatment of Chemoresistant Ovarian Cell Line. 
  • A Western diet induced NAFLD in LDLR(-/)(-) mice is associated with reduced hepatic glutathione synthesis. 
  • A catalytic antioxidant (AEOL 10150) attenuates expression of inflammatory genes in stroke. 
  • A catalytic antioxidant attenuates alveolar structural remodeling in bronchopulmonary dysplasia. 
  • A chemical perspective on the interplay between NO, reactive oxygen species, and reactive nitrogen oxide species. 
  • A combination of two antioxidants (an SOD mimic and ascorbate) produces a pro-oxidative effect forcing Escherichia coli to adapt via induction of oxyR regulon. 
  • A comprehensive evaluation of catalase-like activity of different classes of redox-active therapeutics. 
  • A comprehensive evaluation of the enzymatic and nonenzymatic antioxidant systems in childhood asthma. 
  • A dietary pattern that lowers oxidative stress increases antibodies to oxidized LDL: results from a randomized controlled feeding study. 
  • A manganese porphyrin suppresses oxidative stress and extends the life span of streptozotocin-diabetic rats. 
  • A mathematical model of glutathione metabolism. 
  • A metabolomics comparison of plant-based meat and grass-fed meat indicates large nutritional differences despite comparable Nutrition Facts panels. 
  • A metalloporphyrin antioxidant alters cytokine responses after irradiation in a prostate tumor model. 
  • A randomized trial of glutamine and antioxidants in critically ill patients. 
  • A small molecular weight catalytic metalloporphyrin antioxidant with superoxide dismutase (SOD) mimetic properties protects lungs from radiation-induced injury. 
  • A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damage caused by ultraviolet irradiation. 
  • AHR2 knockdown prevents PAH-mediated cardiac toxicity and XRE- and ARE-associated gene induction in zebrafish (Danio rerio). 
  • ALSUntangled No. 29: MitoQ. 
  • ALSUntangled No. 47: RT001. 
  • Absence of direct antioxidant effects from volatile anesthetics in primary mixed neuronal-glial cultures. 
  • Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer. 
  • Adjuvant therapy after surgical stone management. 
  • Alpha-lipoic acid is ineffective as a topical antioxidant for photoprotection of skin. 
  • Alterations in human trabecular meshwork cell homeostasis by selenium. 
  • Ameliorating the developmental neurotoxicity of chlorpyrifos: a mechanisms-based approach in PC12 cells. 
  • Amelioration of the cytotoxic effects of chemotherapeutic agents by grape seed proanthocyanidin extract. 
  • Amelioration strategies fail to prevent tobacco smoke effects on neurodifferentiation: Nicotinic receptor blockade, antioxidants, methyl donors. 
  • An oxidative stress-based mechanism of doxorubicin cytotoxicity suggests new therapeutic strategies in ABC-DLBCL. 
  • Anticancer therapeutic potential of Mn porphyrin/ascorbate system. 
  • Anticipation of oxidative damage decelerates aging in virgin female medflies: hypothesis tested by statistical modeling. 
  • Antioxidant and DNA methylation-related nutrients and risk of distal colorectal cancer. 
  • Antioxidant and cytotoxic tocopheryl quinones in normal and cancer cells. 
  • Antioxidant defense mechanisms in cultured pleural mesothelial cells. 
  • Antioxidant defenses in killifish (Fundulus heteroclitus) exposed to contaminated sediments and model prooxidants: short-term and heritable responses. 
  • Antioxidant enzyme expression in clinical isolates of Pseudomonas aeruginosa: identification of an atypical form of manganese superoxide dismutase. 
  • Antioxidant intake and cognitive function of elderly men and women: the Cache County Study. 
  • Antioxidant lazaroid U-74006F improves renal function and reduces the expression of cytokines, inducible nitric oxide synthase, and MHC antigens in a syngeneic renal transplant model. Partial support for the response-to-injury hypothesis. 
  • Antioxidant nutrients protect against cyclosporine A nephrotoxicity. 
  • Antioxidant properties of citric acid interfere with the uricase-based measurement of circulating uric acid. 
  • Antioxidant response to exercise-induced oxidative stress and protection by vitamin E. 
  • Antioxidant responses and NRF2 in synergistic developmental toxicity of PAHs in zebrafish. 
  • Antioxidant responses and oxidative stress in sheepshead minnow larvae exposed to Corexit 9500^® or its component surfactant, DOSS. 
  • Antioxidant therapy for atherosclerotic vascular disease: the promise and the pitfalls. 
  • Antioxidants and prevention of gastrointestinal cancers. 
  • Antioxidants preserve macrophage phagocytosis of Pseudomonas aeruginosa during hyperoxia. 
  • Antioxidants suppress mortality in the female NZB x NZW F1 mouse model of systemic lupus erythematosus (SLE). 
  • Antioxidative, antinitrative, and vasculoprotective effects of a peroxisome proliferator-activated receptor-gamma agonist in hypercholesterolemia. 
  • Antitumorigenesis of antioxidants in a transgenic Rac1 model of Kaposi's sarcoma. 
  • Apoptosis and P53 induction in human lung fibroblasts exposed to chromium (VI): effect of ascorbate and tocopherol. 
  • Are antioxidants or other supplements protective for age-related macular degeneration? 
  • Ascorbate-dependent and ascorbate-independent Mn porphyrin cytotoxicity: anticancer activity of Mn porphyrin-based SOD mimics through ascorbate-dependent and -independent routes. 
  • Ascorbic acid increases the severity of spontaneous knee osteoarthritis in a guinea pig model. 
  • Ascorbic acid modulation of iron homeostasis and lysosomal function in trabecular meshwork cells. 
  • Association Between Dietary Intake and Function in Amyotrophic Lateral Sclerosis. 
  • Association Between Early Postoperative Acetaminophen Exposure and Acute Kidney Injury in Pediatric Patients Undergoing Cardiac Surgery. 
  • Association of Vitamin C, Thiamine, and Hydrocortisone Infusion With Long-term Cognitive, Psychological, and Functional Outcomes in Sepsis Survivors: A Secondary Analysis of the Vitamin C, Thiamine, and Steroids in Sepsis Randomized Clinical Trial. 
  • Association of plasma micronutrient levels and urinary isoprostane with risk of lung cancer: the multiethnic cohort study. 
  • Associations of mortality with ocular disorders and an intervention of high-dose antioxidants and zinc in the Age-Related Eye Disease Study: AREDS Report No. 13. 
  • Attenuation of actinic prurigo eruptions with Polypodium leucotomos supplementation. 
  • BDNF mediates neuroprotection against oxygen-glucose deprivation by the cardiac glycoside oleandrin. 
  • Better cognitive performance in elderly taking antioxidant vitamins E and C supplements in combination with nonsteroidal anti-inflammatory drugs: the Cache County Study. 
  • Blood pressure effects of vitamin C: what's the key question? 
  • CDDO-Me, Sulforaphane and tBHQ attenuate the RANKL-induced osteoclast differentiation via activating the NRF2-mediated antioxidant response. 
  • COPD: balancing oxidants and antioxidants. 
  • Carbon monoxide reversibly alters iron homeostasis and respiratory epithelial cell function. 
  • Carbon monoxide, skeletal muscle oxidative stress, and mitochondrial biogenesis in humans. 
  • Case records of the Massachusetts General Hospital. Case 21-2005. A four-week-old male infant with jaundice and thrombocytopenia. 
  • Chemoprevention of NMU-induced rat mammary carcinoma with the combination of melatonin and 9-cis-retinoic acid. 
  • Cholinergic Stimulation Improves Oxidative Stress and Inflammation in Experimental Myocardial Infarction. 
  • Cigarette Smoke Initiates Oxidative Stress-Induced Cellular Phenotypic Modulation Leading to Cerebral Aneurysm Pathogenesis. 
  • Clinical correlates of histopathology in pediatric nonalcoholic steatohepatitis. 
  • Coenzyme Q10: a review of its promise as a neuroprotectant. 
  • Combination drug therapy for Alzheimer's disease: what is evidence-based, and what is not? 
  • Combination therapy for early Alzheimer's disease: what are we waiting for? 
  • Comparative genomics provides new insights into the diversity, physiology, and sexuality of the only industrially exploited tremellomycete: Phaffia rhodozyma. 
  • Concurrent administration of coenzyme Q10 and alpha-tocopherol improves learning in aged mice. 
  • Coordinated changes of mitochondrial biogenesis and antioxidant enzymes during osteogenic differentiation of human mesenchymal stem cells. 
  • Copper complexes containing thiosemicarbazones derived from 6-nitropiperonal: Antimicrobial and biophysical properties. 
  • Critical review of resveratrol in xenobiotic-induced hepatotoxicity. 
  • Cryptococcus neoformans mitochondrial superoxide dismutase: an essential link between antioxidant function and high-temperature growth. 
  • Current and future treatments for cognitive deficits in dementia. 
  • Current status of antioxidant therapy for Alzheimer's Disease. 
  • Cyclosporine increases local glomerular synthesis of reactive oxygen species in rats: effect of vitamin E on cyclosporine nephrotoxicity. 
  • Daily intake of antioxidants in relation to survival among adult patients diagnosed with malignant glioma. 
  • Deficiency of optineurin enhances osteoclast differentiation by attenuating the NRF2-mediated antioxidant response. 
  • Dementia and Alzheimer's disease in community-dwelling elders taking vitamin C and/or vitamin E. 
  • Dicranin, an antimicrobial and 15-lipoxygenase inhibitor from the moss Dicranum scoparium. 
  • Diet and neurocognition: review of evidence and methodological considerations. 
  • Dietary antioxidants and primary prevention of age related macular degeneration: systematic review and meta-analysis. 
  • Distinct effects of endosomal escape and inhibition of endosomal trafficking on gene delivery via electrotransfection. 
  • Distribution of antioxidant enzymes in the normal aged human conjunctiva: an immunocytochemical study. 
  • Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimics. 
  • Dry age-related macular degeneration: mechanisms, therapeutic targets, and imaging. 
  • Early and late administration of MnTE-2-PyP5+ in mitigation and treatment of radiation-induced lung damage. 
  • Editor's Highlight: Metformin Protects Against Acetaminophen Hepatotoxicity by Attenuation of Mitochondrial Oxidant Stress and Dysfunction. 
  • Effect of a metalloporphyrin antioxidant (MnTE-2-PyP) on the response of a mouse prostate cancer model to radiation. 
  • Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). 
  • Effect of vitamin E on tamoxifen-treated breast cancer cells. 
  • Effectiveness of Prevention Strategies for Contrast-Induced Nephropathy: A Systematic Review and Meta-analysis. 
  • Effects of TNFalpha on expression of ICAM-1 in human airway epithelial cells in vitro: oxidant-mediated pathways and transcription factors. 
  • Effects of a manganese (III) porphyrin catalytic antioxidant in a mouse closed head injury model. 
  • Effects of a single bout of ultraendurance exercise on lipid levels and susceptibility of lipids to peroxidation in triathletes. 
  • Effects of genotype and environment on the antioxidant properties of hard winter wheat bran. 
  • Effects of inhaled CO administration on acute lung injury in baboons with pneumococcal pneumonia. 
  • Effects of metalloporphyrin catalytic antioxidants in experimental brain ischemia. 
  • Effects of pharmaconutrients on cellular dysfunction and the microcirculation in critical illness. 
  • Effects of prenatal nicotine exposure on primate brain development and attempted amelioration with supplemental choline or vitamin C: neurotransmitter receptors, cell signaling and cell development biomarkers in fetal brain regions of rhesus monkeys. 
  • Effects of solid-state yeast treatment on the antioxidant properties and protein and fiber compositions of common hard wheat bran. 
  • Endotoxin stress-response in cardiomyocytes: NF-kappaB activation and tumor necrosis factor-alpha expression. 
  • Epigallocatechin-3-Gallate Upregulates miR-221 to Inhibit Osteopontin-Dependent Hepatic Fibrosis. 
  • ErbB1/2 tyrosine kinase inhibitor mediates oxidative stress-induced apoptosis in inflammatory breast cancer cells. 
  • Evaluation of the compounds commonly known as superoxide dismutase and catalase mimics in cellular models. 
  • Evidence of severe mitochondrial oxidative stress and a protective effect of low oxygen in mouse models of inherited photoreceptor degeneration. 
  • Extracellular superoxide dismutase in the airways of transgenic mice reduces inflammation and attenuates lung toxicity following hyperoxia. 
  • Fatigue and Oxidative Stress in Children Undergoing Leukemia Treatment. 
  • Flavin-dependent antioxidant properties of a new series of meso-N,N'-dialkyl-imidazolium substituted manganese(III) porphyrins. 
  • Free radical scavenger specifically prevents ischemic focal ventricular tachycardia. 
  • Fruit and vegetable consumption and risk of distal gastric cancer in the Shanghai Women's and Men's Health studies. 
  • Fruit, vegetable, and antioxidant intakes are lower in older adults with depression. 
  • GLOBAL REACH 2018: intra-arterial vitamin C improves endothelial-dependent vasodilatory function in humans at high altitude. 
  • Generation of hydrogen peroxide and failure of antioxidative responses in pancreatic islets of male C57BL/6 mice are associated with diabetes induced by multiple low doses of streptozotocin. 
  • Genetic Polymorphisms of CFH and ARMS2 Do Not Predict Response to Antioxidants and Zinc in Patients with Age-Related Macular Degeneration: Independent Statistical Evaluations of Data from the Age-Related Eye Disease Study. 
  • Glutamine and antioxidants in critically ill patients. 
  • Glutamine and antioxidants in the critically ill patient: a post hoc analysis of a large-scale randomized trial. 
  • Glutamine: mode of action in critical illness. 
  • Glutathione and zebrafish: Old assays to address a current issue. 
  • Glutathione peroxidase-3 deficiency promotes platelet-dependent thrombosis in vivo. 
  • Glutathione peroxidase-deficient smooth muscle cells cause paracrine activation of normal smooth muscle cells via cyclophilin A. 
  • Gout, hyperuricemia, and the risk of cardiovascular disease: cause and effect? 
  • Hemodynamic effects of metalloporphyrin catalytic antioxidants: structure-activity relationships and species specificity. 
  • Hif-1a suppresses ROS-induced proliferation of cardiac fibroblasts following myocardial infarction. 
  • High lipophilicity of meta Mn(III) N-alkylpyridylporphyrin-based superoxide dismutase mimics compensates for their lower antioxidant potency and makes them as effective as ortho analogues in protecting superoxide dismutase-deficient Escherichia coli. 
  • Homeopathic pathogenetic trials and the constitutional type questionnaire. 
  • Hydroxytyrosol, a natural molecule occurring in olive oil, induces cytochrome c-dependent apoptosis. 
  • Hypercholesterolemia induces oxidant stress that accelerates the ageing of hematopoietic stem cells. 
  • Hypertension and Mitochondrial Oxidative Stress Revisited: Sirtuin 3, the Improved "Antioxidant". 
  • Imbalance between xanthine oxidase and nitric oxide synthase signaling pathways underlies mechanoenergetic uncoupling in the failing heart. 
  • Increased survival of skin flaps by scavengers of superoxide radical. 
  • Induction of the protective antioxidant response element pathway by 6-hydroxydopamine in vivo and in vitro. 
  • Influence of Nitrosative Stress on Fatigue During Childhood Leukemia Treatment. 
  • Influence of oxygen tension on interleukin 1-induced peroxynitrite formation and matrix turnover in articular cartilage. 
  • Inhibition of NF-kappa B and oxidative pathways in human dendritic cells by antioxidative vitamins generates regulatory T cells. 
  • Inhibition of apoptotic signaling and neointimal hyperplasia by tempol and nitric oxide synthase following vascular injury. 
  • Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses. 
  • Inhibition of the transcriptional activator protein nuclear factor kappaB prevents hemodynamic instability associated with the whole-body inflammatory response syndrome. 
  • Interactions of oxygen radicals with airway epithelium. 
  • Intracellular targeting and pharmacological activity of the superoxide dismutase mimics MnTE-2-PyP5+ and MnTnHex-2-PyP5+ regulated by their porphyrin ring substituents. 
  • Investigation of the extraction behavior of the main monoglutamate folates from spinach by liquid chromatography-electrospray ionization tandem mass spectrometry. 
  • Iron homeostasis and eye disease. 
  • Is age-related macular degeneration a manifestation of systemic disease? New prospects for early intervention and treatment. 
  • Is antioxidant use protective of cognitive function in the community-dwelling elderly? 
  • L-arginine or tempol supplementation improves renal and cardiovascular function in rats with reduced renal mass and chronic high salt intake. 
  • Laser-assisted delivery of vitamin C, vitamin E, and ferulic acid formula serum decreases fractional laser postoperative recovery by increased beta fibroblast growth factor expression. 
  • Lipophilicity of potent porphyrin-based antioxidants: comparison of ortho and meta isomers of Mn(III) N-alkylpyridylporphyrins. 
  • Long-term administration of a small molecular weight catalytic metalloporphyrin antioxidant, AEOL 10150, protects lungs from radiation-induced injury. 
  • Low molecular weight catalytic metalloporphyrin antioxidant AEOL 10150 protects lungs from fractionated radiation. 
  • Low-Flow Domiciliary Oxygen as a Mechanism of Ongoing Oxidative Stress. 
  • MMP-14 and TIMP-2 overexpression protects against hydroquinone-induced oxidant injury in RPE: implications for extracellular matrix turnover. 
  • Manganese porphyrin redox state in endothelial cells: Resonance Raman studies and implications for antioxidant protection towards peroxynitrite. 
  • Manganese porphyrin reduces renal injury and mitochondrial damage during ischemia/reperfusion. 
  • Manganese porphyrin reduces retinal injury induced by ocular hypertension in rats. 
  • Mechanisms of the antioxidant effects of nitric oxide. 
  • Mechanistic insights into the cytotoxicity and genotoxicity induced by glycidamide in human mammary cells. 
  • Melatonin and risk of mortality in subjects with aneurysmal subarachnoid hemorrhage. 
  • Melatonin regulates antioxidant strategy in response to continuous salt stress in rice seedlings. 
  • Melatonin regulates energy balance and attenuates fever in Siberian hamsters. 
  • Mesenchymal Stromal Cells Deficient in Autophagy Proteins Are Susceptible to Oxidative Injury and Mitochondrial Dysfunction. 
  • Meta-Analysis of Carvedilol for the Prevention of Anthracycline-Induced Cardiotoxicity. 
  • Metalloporphyrin antioxidants ameliorate normal tissue radiation damage in rat brain. 
  • Metalloporphyrins are potent inhibitors of lipid peroxidation. 
  • Metalloporphyrins as therapeutic catalytic oxidoreductants in central nervous system disorders. 
  • Microarray analysis of murine retinal light damage reveals changes in iron regulatory, complement, and antioxidant genes in the neurosensory retina and isolated RPE. 
  • Minocycline protects against neuronal mitochondrial dysfunction and cognition impairment. 
  • Mito-tempo protects against acute liver injury but induces limited secondary apoptosis during the late phase of acetaminophen hepatotoxicity. 
  • Mitochondria-targeted antioxidant Mito-Tempo protects against acetaminophen hepatotoxicity. 
  • Mitochondrial Dysfunction in Critical Illness: Implications for Nutritional Therapy. 
  • Mitochondrial ROS cause motor deficits induced by synaptic inactivity: Implications for synapse pruning. 
  • Mn porphyrin regulation of aerobic glycolysis: implications on the activation of diabetogenic immune cells. 
  • Mn porphyrin-based superoxide dismutase (SOD) mimic, MnIIITE-2-PyP5+, targets mouse heart mitochondria. 
  • Mn(III) Porphyrin, MnTnBuOE-2-PyP5+, Commonly Known as a Mimic of Superoxide Dismutase Enzyme, Protects Cardiomyocytes from Hypoxia/Reoxygenation Induced Injury via Reducing Oxidative Stress. 
  • Mn(III) meso-tetrakis-(N-ethylpyridinium-2-yl) porphyrin mitigates total body irradiation-induced long-term bone marrow suppression. 
  • MnSOD is implicated in accelerated wound healing upon Negative Pressure Wound Therapy (NPWT): A case in point for MnSOD mimetics as adjuvants for wound management. 
  • Modern approaches to photoprotection. 
  • Motor deficits are triggered by reperfusion-reoxygenation injury as diagnosed by MRI and by a mechanism involving oxidants. 
  • Mouse spinal cord compression injury is ameliorated by intrathecal cationic manganese(III) porphyrin catalytic antioxidant therapy. 
  • NADPH oxidase promotes NF-kappaB activation and proliferation in human airway smooth muscle. 
  • Nano-C60 cytotoxicity is due to lipid peroxidation. 
  • Neurogenic differentiation of murine and human adipose-derived stromal cells. 
  • Neuroprotection from delayed postischemic administration of a metalloporphyrin catalytic antioxidant. 
  • Neutrophil elastase induces MUC5AC gene expression in airway epithelium via a pathway involving reactive oxygen species. 
  • Nitric oxide and redox regulation in the liver: part II. Redox biology in pathologic hepatocytes and implications for intervention. 
  • Nitroxyl anion regulation of the NMDA receptor. 
  • Non-cholinergic strategies for treating and preventing Alzheimer's disease. 
  • Nrf2 inactivation enhances placental angiogenesis in a preeclampsia mouse model and improves maternal and fetal outcomes. 
  • Nrf2, a multi-organ protector? 
  • Nuclear factor erythroid-derived factor 2-related factor 2 regulates transcription of CCAAT/enhancer-binding protein β during adipogenesis. 
  • Nutrition and skin ulcers. 
  • Nutrition, dietary interventions and prostate cancer: the latest evidence. 
  • Nutritional supplements in ADHD. 
  • Opioid use affects antioxidant activity and purine metabolism: preliminary results. 
  • Optical imaging reveals elevated intracellular chloride in hippocampal pyramidal neurons after oxidative stress. 
  • Optimizing the dose of glutamine dipeptides and antioxidants in critically ill patients: a phase I dose-finding study. 
  • Oxidants and antioxidants in alveolar epithelial type II cells: in situ, freshly isolated, and cultured cells. 
  • Oxidants, antioxidants and the ischemic brain. 
  • Oxidative Stress and Total Antioxidant Status During Internal Carotid Artery Clamping with or without Shunting: An Experimental Pilot Study. 
  • Oxidative mechanisms contributing to the developmental neurotoxicity of nicotine and chlorpyrifos. 
  • Oxidative stress and inflammation contribute to lung toxicity after a common breast cancer chemotherapy regimen. 
  • Oxidative stress from diverse developmental neurotoxicants: antioxidants protect against lipid peroxidation without preventing cell loss. 
  • Oxidative stress in cardiovascular disease. 
  • Oxidative stress in toxicology: established mammalian and emerging piscine model systems. 
  • Oxidative stress induces itch via activation of transient receptor potential subtype ankyrin 1 in mice. 
  • Oxidative stress, oxidative balance score, and hypertension among a racially diverse population. 
  • Oxidized low-density lipoprotein induces apoptosis in endothelial progenitor cells by inactivating the phosphoinositide 3-kinase/Akt pathway. 
  • Oxygen toxicity and iron accumulation in the lungs of mice lacking heme oxygenase-2. 
  • PGC1-α over-expression prevents metabolic alterations and soleus muscle atrophy in hindlimb unloaded mice. 
  • Peroxynitrite formation in nitric oxide-exposed submitochondrial particles: detection, oxidative damage and catalytic removal by Mn-porphyrins. 
  • Pharmacokinetics of the potent redox-modulating manganese porphyrin, MnTE-2-PyP(5+), in plasma and major organs of B6C3F1 mice. 
  • Phase III trial of selenium to prevent prostate cancer in men with high-grade prostatic intraepithelial neoplasia: SWOG S9917. 
  • Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis. 
  • Placental IDO and oxidative damage in pre-eclampsia: fresh chicken or fresh eggs? Preface. 
  • Polyglutamine expansion inhibits respiration by increasing reactive oxygen species in isolated mitochondria. 
  • Prenatal nicotine exposure in rhesus monkeys compromises development of brainstem and cardiac monoamine pathways involved in perinatal adaptation and sudden infant death syndrome: amelioration by vitamin C. 
  • Prevention and health services delivery. 
  • Prevention and health services delivery. 
  • Prevention of influenza-induced lung injury in mice overexpressing extracellular superoxide dismutase. 
  • Pro-thrombotic and pro-oxidant effects of diet-induced hyperhomocysteinemia. 
  • Probing and preventing quantum dot-induced cytotoxicity with multimodal alpha-lipoic acid in multiple dimensions of the peripheral nervous system. 
  • Probucol increases glutathione peroxidase-1 activity and displays long-lasting protection against methylmercury toxicity in cerebellar granule cells. 
  • Prochelators triggered by hydrogen peroxide provide hexadentate iron coordination to impede oxidative stress. 
  • Prolonged production of hydroxyl radical in rat hippocampus after brain ischemia-reperfusion is decreased by 21-aminosteroids. 
  • Protective effect of 21-aminosteroid pretreatment in peripheral nerve low-load crush injury in mature and immature rats. 
  • Protective role of ortho-substituted Mn(III) N-alkylpyridylporphyrins against the oxidative injury induced by tert-butylhydroperoxide. 
  • Proteomics characterization of cell membrane blebs in human retinal pigment epithelium cells. 
  • Quality of potent Mn porphyrin-based SOD mimics and peroxynitrite scavengers for pre-clinical mechanistic/therapeutic purposes. 
  • Quitting smoking raises whole blood glutathione. 
  • ROS signaling, oxidative stress and Nrf2 in pancreatic beta-cell function. 
  • Radiation and a metalloporphyrin radioprotectant in a mouse prostate tumor model. 
  • Radioprotective effects of manganese-containing superoxide dismutase mimics on ataxia-telangiectasia cells. 
  • Rationale and design for the development of a novel nitroxyl donor in patients with acute heart failure. 
  • Reactive oxygen species: from health to disease. 
  • Redox regulation of the rat hepatocyte iNOS promoter. 
  • Reduced risk of Alzheimer disease in users of antioxidant vitamin supplements: the Cache County Study. 
  • Refining the role of BRCA1 in combating oxidative stress. 
  • Regulation of the extracellular antioxidant selenoprotein plasma glutathione peroxidase (GPx-3) in mammalian cells. 
  • Requirement for reactive oxygen species in serum-induced and platelet-derived growth factor-induced growth of airway smooth muscle. 
  • Resistance to cerebral ischemic injury in UCP2 knockout mice: evidence for a role of UCP2 as a regulator of mitochondrial glutathione levels. 
  • Resveratrol prevention of oxidative stress damage to lens epithelial cell cultures is mediated by forkhead box O activity. 
  • Resveratrol worsens survival in SCID mice with prostate cancer xenografts in a cell-line specific manner, through paradoxical effects on oncogenic pathways. 
  • SAHIT Investigators--on the outcome of some subarachnoid hemorrhage clinical trials. 
  • SOD enzymes and their mimics in cancer: pro vs anti-odixative mode of action-part II. 
  • Sarcopenia in Patients with Chronic Liver Disease: Can It Be Altered by Diet and Exercise? 
  • Scurvy mimicking osteomyelitis: case report and review of the literature. 
  • Selenium Augments microRNA Directed Reprogramming of Fibroblasts to Cardiomyocytes via Nanog. 
  • Selenium toxicity: cause and effects in aquatic birds. 
  • Sirtuin-1 expression and activity is diminished in aged liver grafts. 
  • Stem cell therapy for liver disease: parameters governing the success of using bone marrow mesenchymal stem cells. 
  • Studies of ischemia-reperfusion injury in skeletal muscle: efficacy of 21-aminosteroids on microcirculation and muscle contraction after an extended period of warm ischemia. 
  • Superoxide dismutase mimetic reduces hypoxia-induced O2*-, TGF-beta, and VEGF production by macrophages. 
  • Superoxide enhances interleukin 1beta-mediated transcription of the hepatocyte-inducible nitric oxide synthase gene. 
  • Suppression of RelB-mediated manganese superoxide dismutase expression reveals a primary mechanism for radiosensitization effect of 1alpha,25-dihydroxyvitamin D(3) in prostate cancer cells. 
  • Sustained stress response after oxidative stress in trabecular meshwork cells. 
  • Sympathetic nervous system inhibition increases hepatic progenitors and reduces liver injury. 
  • Synthesis and in vitro antioxidant properties of manganese(III) beta-octabromo-meso-tetrakis(4-carboxyphenyl)porphyrin. 
  • Targeting proximal tubule mitochondrial dysfunction attenuates the renal disease of methylmalonic acidemia. 
  • Tempol therapy attenuates medial smooth muscle cell apoptosis and neointima formation after balloon catheter injury in carotid artery of diabetic rats. 
  • Tepoxalin enhances the activity of an antioxidant, pyrrolidine dithiocarbamate, in attenuating tumor necrosis factor alpha-induced apoptosis in WEHI 164 cells. 
  • The Cryptococcus neoformans catalase gene family and its role in antioxidant defense. 
  • The Nrf2-ARE pathway: an indicator and modulator of oxidative stress in neurodegeneration. 
  • The antioxidant, MnTE-2-PyP, prevents side-effects incurred by prostate cancer irradiation. 
  • The challenging task of treating painful chronic pancreatitis. 
  • The effect of melatonin treatment regimen on mammary adenocarcinoma development in HER-2/neu transgenic mice. 
  • The effects of tempol on cyclophosphamide-induced oxidative stress in rat micturition reflexes. 
  • The injured cochlea as a target for inflammatory processes, initiation of cell death pathways and application of related otoprotectives strategies. 
  • The transcriptional response to oxidative stress during vertebrate development: effects of tert-butylhydroquinone and 2,3,7,8-tetrachlorodibenzo-p-dioxin. 
  • The uric acid transporter SLC2A9 is a direct target gene of the tumor suppressor p53 contributing to antioxidant defense. 
  • Thermal stability of the prototypical Mn porphyrin-based superoxide dismutase mimic and potent oxidative-stress redox modulator Mn(III) meso-tetrakis(N-ethylpyridinium-2-yl)porphyrin chloride, MnTE-2-PyP(5+). 
  • Thermodynamic analysis of protein-ligand interactions in complex biological mixtures using a shotgun proteomics approach. 
  • Thiol peroxidase is critical for virulence and resistance to nitric oxide and peroxide in the fungal pathogen, Cryptococcus neoformans. 
  • Thromboxane receptor signalling in renal ischemia reperfusion injury. 
  • To oxidize or not to oxidize? 
  • Topical and oral administration of the natural water-soluble antioxidant from spinach reduces the multiplicity of papillomas in the Tg.AC mouse model. 
  • Total dietary antioxidant index and survival in patients with glioblastoma multiforme. 
  • Toxicity of oxidized low density lipoproteins for vascular smooth muscle cells and partial protection by antioxidants. 
  • Transcription factor Nrf2 hyperactivation in early-phase renal ischemia-reperfusion injury prevents tubular damage progression. 
  • Treating gout with pegloticase, a PEGylated urate oxidase, provides insight into the importance of uric acid as an antioxidant in vivo. 
  • Tumor necrosis factor alpha (TNF alpha)-induced ICAM-1 surface expression in airway epithelial cells in vitro: possible signal transduction mechanisms. 
  • Two faces of nitric oxide: implications for cellular mechanisms of oxygen toxicity. 
  • UV photoprotection by combination topical antioxidants vitamin C and vitamin E. 
  • Ubiquinone, idebenone, and kinetin provide ineffective photoprotection to skin when compared to a topical antioxidant combination of vitamins C and E with ferulic acid. 
  • Ultraviolet light and free radicals: an immunologic theory of epidermal carcinogenesis. 
  • Vitamin C supplementation in pregnancy--does it decrease rates of preterm birth? A systematic review. 
  • Vitamin E and breast cancer: a review. 
  • Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). 
  • Vitamin E inhibits abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E-deficient mice. 
  • Vitamin E, vitamin C, and exercise. 
  • Zonisamide for weight reduction in obese adults: a 1-year randomized controlled trial. 
  • [In vitro studies on antioxidant and antimicrobial activities of polysaccharide from Lycoris aurea]. 
  • microRNA miR-144 modulates oxidative stress tolerance and associates with anemia severity in sickle cell disease. 
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  Keywords of People

  • Sunday, Mary Elizabeth Anne, Professor of Pathology, Cell Biology