Apoferritins

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  Subject Areas on Research

  • Age-dependent retinal iron accumulation and degeneration in hepcidin knockout mice. 
  • Apoferritin protein cages: a novel drug nanocarrier for photodynamic therapy. 
  • Ceruloplasmin/hephaestin knockout mice model morphologic and molecular features of AMD. 
  • Ferritin heavy chain-mediated iron homeostasis and subsequent increased reactive oxygen species production are essential for epithelial-mesenchymal transition. 
  • Immunolocalization and regulation of iron handling proteins ferritin and ferroportin in the retina. 
  • Intralysosomal iron induces lysosomal membrane permeabilization and cathepsin D-mediated cell death in trabecular meshwork cells exposed to oxidative stress. 
  • Routine single particle CryoEM sample and grid characterization by tomography. 
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  Keywords of People

  • Liton, Paloma Borrajo, Associate Professor in Ophthalmology, Pathology