Arginase

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  Subject Areas on Research

  • Arginase1 Deficiency in Monocytes/Macrophages Upregulates Inducible Nitric Oxide Synthase To Promote Cutaneous Contact Hypersensitivity. 
  • Differential expression of arginase and iNOS in the lung in sepsis. 
  • Dimethylarginines: endogenous inhibitors of nitric oxide synthesis in children with falciparum malaria. 
  • Disrupted spermine homeostasis: a novel mechanism in polyglutamine-mediated aggregation and cell death. 
  • Effects of arginase isoforms on NO Production by nNOS. 
  • Increased arginase II and decreased NO synthesis in endothelial cells of patients with pulmonary arterial hypertension. 
  • Increased plasma arginase activity in human sepsis: association with increased circulating neutrophils. 
  • Induction of arginase isoforms in the lung during hyperoxia. 
  • Modulation of murine dendritic cell function by adenine nucleotides and adenosine: involvement of the A(2B) receptor. 
  • Monocyte polarization in children with falciparum malaria: relationship to nitric oxide insufficiency and disease severity. 
  • Neutrophils with myeloid derived suppressor function deplete arginine and constrain T cell function in septic shock patients. 
  • Nitric oxide production and regulation of neuronal NOS in tyrosine hydroxylase containing neurons. 
  • Nutrition Modulation of Cardiotoxicity and Anticancer Efficacy Related to Doxorubicin Chemotherapy by Glutamine and ω-3 Polyunsaturated Fatty Acids. 
  • Pollutant particles induce arginase II in human bronchial epithelial cells. 
  • Red blood cell arginase suppresses Jurkat (T cell) proliferation by depleting arginine. 
  • The arginase inhibitor Nω-hydroxy-nor-arginine (nor-NOHA) induces apoptosis in leukemic cells specifically under hypoxic conditions but CRISPR/Cas9 excludes arginase 2 (ARG2) as the functional target. 
  • Urea-cycle enzyme deficiencies and an increased nitrogen load producing hyperammonemia in Reye's syndrome.