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Subject Areas on Research
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1p36 is a preferential target of chromosome 1 deletions in astrocytic tumours and homozygously deleted in a subset of glioblastomas.
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A case of Ollier's disease associated with two intracranial gliomas.
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A glial fibrillary acidic protein-expressing and tumorigenic cell line derived from an avian sarcoma virus-induced rat astrocytoma.
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A low-frequency variant at 8q24.21 is strongly associated with risk of oligodendroglial tumors and astrocytomas with IDH1 or IDH2 mutation.
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A phase II study of every other day high-dose ifosfamide in pediatric brain tumors: a Pediatric Oncology Group Study.
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ACVR1 R206H cooperates with H3.1K27M in promoting diffuse intrinsic pontine glioma pathogenesis.
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Acquired stuttering due to recurrent anaplastic astrocytoma.
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An analysis of radiotherapy data from the CNS cancer consortium's randomized prospective trial comparing AZQ to BCNU in the treatment of patients with primary malignant brain tumors. The CNS cancer consortium.
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An intermediate filament-associated protein, p50, recognized by monoclonal antibodies.
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Association of preoperative depression and survival after resection of malignant brain astrocytoma.
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Associations of high-grade glioma with glioma risk alleles and histories of allergy and smoking.
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Benzodiazepine and beta-adrenergic receptor ligands independently stimulate phospholipid methylation.
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Bevacizumab, irinotecan, temozolomide, tyrosine kinase inhibition, and MEK inhibition are effective against pleomorphic xanthoastrocytoma regardless of V600E status.
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Brain Perfusion and Diffusion Abnormalities in Children Treated for Posterior Fossa Brain Tumors.
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Brain tumor types induced by the Schmidt-Ruppin strain of Rous sarcoma virus in inbred Fischer rats.
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Brain tumors induced in dogs by the Schmidt-Ruppin strain of Rous sarcoma virus. Neuropathological and immunological observations.
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CDKN2A loss is associated with shortened overall survival in lower-grade (World Health Organization Grades II-III) astrocytomas.
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CDKN2A/B Loss Is Associated with Anaplastic Transformation in a Case of NTRK2 Fusion-positive Pilocytic Astrocytoma.
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Carboplatin chemotherapy for progressive intramedullary spinal cord low-grade gliomas in children: three case studies and a review of the literature.
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Carboplatin treatment of progressive optic pathway gliomas to delay radiotherapy.
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Caspase 8 is absent or low in many ex vivo gliomas.
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Cdk5 mediates changes in morphology and promotes apoptosis of astrocytoma cells in response to heat shock.
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Cell adhesion to fibronectin and tenascin: quantitative measurements of initial binding and subsequent strengthening response.
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Cell adhesion to fibronectin and tenascin: quantitative measurements of initial binding and subsequent strengthening response.
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Cellular immunity in rats with primary brain tumors: inhibition of macrophage migration by soluble extracts of avian sarcoma virus-induced tumors.
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Central Nervous System Cancers, Version 3.2020, NCCN Clinical Practice Guidelines in Oncology.
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Cerebral phaeohyphomycosis mimics high-grade astrocytoma.
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Characteristics of patients ≥10 years of age with diffuse intrinsic pontine glioma: a report from the International DIPG/DMG Registry.
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Characterization of a spontaneous murine astrocytoma and abrogation of its tumorigenicity by cytokine secretion.
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Chemotherapy for pilocytic astrocytomas.
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Chromosomal characteristics of childhood brain tumors.
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Clinical characteristics and treatment of malignant brainstem gliomas in elderly patients.
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Clinical experience with alpha-particle emitting 211At: treatment of recurrent brain tumor patients with 211At-labeled chimeric antitenascin monoclonal antibody 81C6.
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Colocalization of gadolinium-diethylene triamine pentaacetic acid with high-molecular-weight molecules after intracerebral convection-enhanced delivery in humans.
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Comparative genomic hybridization analysis of astrocytomas: prognostic and diagnostic implications.
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Comparison of intensity-modulated tomotherapy with stereotactically guided conformal radiotherapy for brain tumors.
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Computed tomography of virally induced canine brain tumors: a preliminary report.
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Constrained customization of non-coplanar beam orientations in radiotherapy of brain tumours.
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Conventional external beam radiotherapy for central nervous system malignancies.
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Correlation of 1p-19q-defects in human gliomas with the light microscopic appearance of oligodendroglioma.
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Correlation of neuropathologic findings, computerized tomographic and high-resolution ultrasound scans of canine avian sarcoma virus-induced brain tumors.
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Cortical localization of temporal lobe language sites in patients with gliomas.
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Criteria for termination of phase II chemotherapy for patients with progressive or recurrent brain tumor.
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Curcumin inhibits LPS-induced CCL2 expression via JNK pathway in C6 rat astrocytoma cells.
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Cyclophosphamide for the treatment of progressive low-grade astrocytoma: a Pediatric Oncology Group phase II Study.
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Differential Apaf-1 levels allow cytochrome c to induce apoptosis in brain tumors but not in normal neural tissues.
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Differential expression of ros oncogene in primary human astrocytomas and astrocytoma cell lines.
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Disruption of wild-type IDH1 suppresses D-2-hydroxyglutarate production in IDH1-mutated gliomas.
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Dural venous sinus thrombosis in anaplastic astrocytoma following concurrent temozolomide and focal brain radiotherapy plus bevacizumab.
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EGFR and EGFRvIII interact with PUMA to inhibit mitochondrial translocalization of PUMA and PUMA-mediated apoptosis independent of EGFR kinase activity.
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EGFRvIII mCAR-modified T-cell therapy cures mice with established intracerebral glioma and generates host immunity against tumor-antigen loss.
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Effectiveness of radiotherapy for elderly patients with anaplastic gliomas.
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Enhanced chemotherapy delivery by intraarterial infusion and blood-brain barrier disruption in malignant brain tumors: the Sherbrooke experience.
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Enhanced optical imaging of rat gliomas and tumor margins.
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Epidemiology and Molecular Epidemiology.
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Epidemiology of brainstem high-grade gliomas in children and adolescents in the United States, 2000-2017.
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Epidemiology of primary malignant non-osseous spinal tumors in the United States.
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Evaluation of apparent diffusion coefficient thresholds for diagnosis of medulloblastoma using diffusion-weighted imaging.
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Everolimus tablets for patients with subependymal giant cell astrocytoma.
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Ex vivo pediatric brain tumors express Fas (CD95) and FasL (CD95L) and are resistant to apoptosis induction.
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Exomic sequencing of four rare central nervous system tumor types.
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Expanded analysis of high-grade astrocytoma with piloid features identifies an epigenetically and clinically distinct subtype associated with neurofibromatosis type 1.
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Extent of surgical resection is independently associated with survival in patients with hemispheric infiltrating low-grade gliomas.
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FDG-PET in the selection of brain lesions for biopsy.
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Factors influencing the cell type of brain tumors induced in dogs by Schmidt-Ruppin Rous sarcoma virus.
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False-positive MRI detection of recurrent or metastatic pediatric infratentorial tumors.
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False-positive spinal MR findings for subarachnoid spread of primary CNS tumor in postoperative pediatric patients.
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GD2-CAR T cell therapy for H3K27M-mutated diffuse midline gliomas.
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Gadolinium enhancement of the leptomeninges caused by hydrocephalus: a potential mimic of leptomeningeal metastasis.
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Gamma-aminobutyric acid inhibits synergistic interleukin-6 release but not transcriptional activation in astrocytoma cells.
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Gender differences in facial expression recognition in survivors of pediatric brain tumors.
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General immunocompetence of rats bearing avian sarcoma virus-induced intracranial tumors.
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Genetic analysis of intracranial tumors in a murine model of glioma demonstrate a shift in gene expression in response to host immunity.
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Glioma-associated antigens defined by monoclonal antibodies against an avian sarcoma virus-induced rat astrocytoma.
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Gliomas of the optic nerve: histological, immunohistochemical (MIB-1 and p53), and MRI analysis.
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Gliomatosis cerebri: cytologic and autopsy findings in a case involving the entire neuraxis.
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Glutathione S-transferase polymorphisms and survival in primary malignant glioma.
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Glutathione content and glutathione-S-transferase expression in 1,3-bis(2-chloroethyl)-1-nitrosourea-resistant human malignant astrocytoma cell lines.
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Histologically benign, clinically aggressive: Progressive non-optic pathway pilocytic astrocytomas in adults with NF1.
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Human brain glycogen phosphorylase. Cloning, sequence analysis, chromosomal mapping, tissue expression, and comparison with the human liver and muscle isozymes.
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IDH1 and IDH2 mutations in gliomas.
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INTRACRANIAL TUMORS IN INFANCY AND CHILDHOOD. A CLINICAL STUDY OF TWENTY CASES.
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Identification of distinct and overlapping cortical areas for bilingual naming and reading using cortical stimulation. Case report.
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Identification of glial filament protein and vimentin in the same intermediate filament system in human glioma cells.
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Immunobiology of malignant astrocytomas.
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Immunobiology of primary intracranial tumors.
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Immunohistochemical detection of the DNA repair enzyme O6-methylguanine-DNA methyltransferase in formalin-fixed, paraffin-embedded astrocytomas.
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Immunohistochemical study of glial fibrillary acidic protein in avian sarcoma virus-induced gliomas in dogs.
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Impact of Tumor Histology on Resectability and Neurological Outcome in Primary Intramedullary Spinal Cord Tumors: A Single-Center Experience With 102 Patients.
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Improved grading of IDH-mutated astrocytic gliomas.
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Improved survival in the largest national cohort of adults with cerebellar versus supratentorial low-grade astrocytomas.
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Independent association of extent of resection with survival in patients with malignant brain astrocytoma.
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Induction of transformational changes in normal endothelial cells by cultured human astrocytoma cells.
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Infiltrating spinal cord astrocytomas: Epidemiology, diagnosis, treatments and future directions.
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Influence of age at inoculation on avian oncornavirus-induced brain tumor incidence, tumor morphology, and postinoculation survival in F344 rats.
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Influence of the type of surgery on the histologic diagnosis in patients with anaplastic gliomas.
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Intraventricular Pilocytic Astrocytoma With KIAA1549/BRAF Fusion Arising in a 44-Year Old.
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Irinotecan therapy in adults with recurrent or progressive malignant glioma.
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Leptomeningeal dissemination of optic pathway gliomas in three children.
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Localized variation in ancestral admixture identifies pilocytic astrocytoma risk loci among Latino children.
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Long-term health and social function in adult survivors of paediatric astrocytoma: A report from the Childhood Cancer Survivor Study.
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Long-term outcomes of primarily metastatic juvenile pilocytic astrocytoma in children.
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Long-term use of temozolomide: could you use temozolomide safely for life in gliomas?
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Low-grade astrocytomas: the prognostic value of fibrillary, gemistocytic, and protoplasmic tumor histology.
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Low-grade gliomas: dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging--prediction of patient clinical response.
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Lymphocyte subpopulations and responsiveness in rats bearing intracranial tumors induced by avian sarcoma virus.
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Lymphomas and high-grade astrocytomas: comparison of water diffusibility and histologic characteristics.
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MGMT: Immunohistochemical Detection in High-Grade Astrocytomas.
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Magnetic resonance perfusion for differentiating low-grade from high-grade gliomas at first presentation.
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Malignant supratentorial glial-neuronal neoplasms: report of two cases and review of the literature.
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Management of tumor bed cysts after chemotherapeutic wafer implantation. Report of four cases.
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Metabolomic profiling of sphingolipids in human glioma cell lines by liquid chromatography tandem mass spectrometry.
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Methylation profiling of paediatric pilocytic astrocytoma reveals variants specifically associated with tumour location and predictive of recurrence.
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Mitogenic and progenitor gene programmes in single pilocytic astrocytoma cells.
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Molecular biomarker-defined brain tumors: Epidemiology, validity, and completeness in the United States.
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Molecular genetic aspects of oligodendrogliomas including analysis by comparative genomic hybridization.
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Molecular markers of prognosis in astrocytic tumors.
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Molecular pathogenesis of malignant gliomas.
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Molecular profiling of different glioma specimens from an Ollier disease patient suggests a multifocal disease process in the setting of IDH mosaicism.
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Monoclonal antibodies reactive with epitopes restricted to glial fibrillary acidic proteins of several species.
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Morphologic and molecular genetic aspects of oligodendroglial neoplasms.
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Morphologic observations of brain tumors in PD4 hamsters induced by four strains of avian sarcoma virus.
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Multicenter phase II trial of temozolomide in patients with anaplastic astrocytoma or anaplastic oligoastrocytoma at first relapse. Temodal Brain Tumor Group.
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Multifocal anaplastic astrocytoma in a patient with hereditary colorectal cancer, transcobalamin II deficiency, agenesis of the corpus callosum, mental retardation, and inherited PMS2 mutation.
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Mutant metabolic enzymes are at the origin of gliomas.
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Mutations of PIK3CA in anaplastic oligodendrogliomas, high-grade astrocytomas, and medulloblastomas.
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Myristoylated alpha subunits of guanine nucleotide-binding regulatory proteins.
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Neuronal-astrocyte metabolic interactions: understanding the transition into abnormal astrocytoma metabolism.
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Oligodendroglioma and juvenile pilocytic astrocytoma presenting as synchronous primary brain tumors. Case report with histological and molecular differentiation of the tumors and review of the literature.
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Osteoblastic metastases from astrocytomas: a report of two cases.
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Paclitaxel for the treatment of progressive or recurrent childhood brain tumors: a pediatric oncology phase II study.
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Painful generalised clonic and tonic-clonic seizures with retained consciousness.
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Partial purification and characterization of a murine glioma-associated antigen defined by syngeneic rat monoclonal antibodies.
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Pattern of failure in anaplastic glioma patients with an IDH1/2 mutation.
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Patterns of the early, gross chromosomal changes in malignant human gliomas.
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Pediatric Central Nervous System Tumors in Nepal: Retrospective Analysis and Literature Review of Low- and Middle-Income Countries.
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Pediatric brain stem tumors: patterns of treatment failure and their implications for radiotherapy.
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Persistent outpatient hyperglycemia is independently associated with decreased survival after primary resection of malignant brain astrocytomas.
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Phase 1 dose escalation trial of the safety and pharmacokinetics of cabozantinib concurrent with temozolomide and radiotherapy or temozolomide after radiotherapy in newly diagnosed patients with high-grade gliomas.
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Phase 1 trial of irinotecan plus BCNU in patients with progressive or recurrent malignant glioma.
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Phase 2 study of temozolomide in children and adolescents with recurrent central nervous system tumors: a report from the Children's Oncology Group.
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Phase 2 trial of BCNU plus irinotecan in adults with malignant glioma.
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Phase I study of Gliadel wafers plus temozolomide in adults with recurrent supratentorial high-grade gliomas.
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Phase I trial of carmustine plus O6-benzylguanine for patients with recurrent or progressive malignant glioma.
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Phase II diaziquone-based chemotherapy trials in patients with anaplastic supratentorial astrocytic neoplasms.
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Phase II study of Gleevec plus hydroxyurea in adults with progressive or recurrent low-grade glioma.
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Phase II study of imatinib mesylate and hydroxyurea for recurrent grade III malignant gliomas.
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Phase II study of irinotecan (CPT-11) in children with high-risk malignant brain tumors: the Duke experience.
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Phase II trial of murine (131)I-labeled antitenascin monoclonal antibody 81C6 administered into surgically created resection cavities of patients with newly diagnosed malignant gliomas.
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Phospholipid methylation: a possible mechanism of signal transduction across biomembranes.
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Pilocytic astrocytoma: correlation between the initial imaging features and clinical aggressiveness.
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Pilocytic astrocytomas: where do they belong in cancer reporting?
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Poliovirus Receptor (CD155) Expression in Pediatric Brain Tumors Mediates Oncolysis of Medulloblastoma and Pleomorphic Xanthoastrocytoma.
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Postradiation cerebellar necrosis mimicking tumor: MR appearance.
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Prognostic value of magnetic resonance imaging-guided stereotactic biopsy in the evaluation of recurrent malignant astrocytoma compared with a lesion due to radiation effect.
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Prospective study of neuropsychologic testing and quality-of-life assessment of adults with primary malignant brain tumors.
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Purification and biochemical characterization of gamma-glutamylcysteine synthetase from a human malignant astrocytoma cell line.
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R-type virus-like particles in avian sarcoma virus-induced rat central nervous system tumors.
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Radiation Therapy for IDH-Mutant Grade 2 and Grade 3 Diffuse Glioma: An ASTRO Clinical Practice Guideline.
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Recent advances in intradural spinal tumors.
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Recent advances in the treatment of malignant astrocytoma.
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Recurrence of astrocytoma of optic nerve after 48 years.
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Recurrent brain tumors in children.
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Redox properties of cytochrome oxidase and vascular reactivity of astrocytomas and neuroblastomas in vivo.
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Reduction in Late Mortality among 5-Year Survivors of Childhood Cancer.
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Regional blood flow in avian sarcoma virus (ASV)-induced brain tumors.
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Regional blood-to-tissue transport in avian sarcoma virus (ASV)-induced brain tumors.
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Relation between Irofulven (MGI-114) systemic exposure and tumor response in human solid tumor xenografts.
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Relationship of the demonstration of intermediate filament protein to kinetics of three human neuroepithelial tumor cell lines. Lack of neural-related proteins in most cells in S phase: a double-labeled immunohistochemical study on matrix cultures.
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Resolution of exudative retinal detachment from retinal astrocytoma following photodynamic therapy.
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Sequential adsorption analysis of antibodies to neuroectodermal cells by an indirect quantitative method.
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Small ubiquitin-like modifier 1-3 conjugation [corrected] is activated in human astrocytic brain tumors and is required for glioblastoma cell survival.
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Social functioning and facial expression recognition in survivors of pediatric brain tumors.
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Solitary astrocytic hamartoma simulating retinoblastoma.
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Somatic mutations in the neurofibromatosis 1 gene in gliomas and primitive neuroectodermal tumours.
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Specificity, cross-reactivity, and affinity of 125I-labeled antiglioma antibodies for monolayers of cultured glioma cells.
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Spinal cord astrocytomas: progresses in experimental and clinical investigations for developing recovery neurobiology-based novel therapies.
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Spontaneous hemorrhage associated with a pilomyxoid astrocytoma. Case report.
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Structural analysis of a human glial variant laminin.
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Successful desensitization to carboplatin in patients with systemic hypersensitivity reactions.
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Successful treatment of childhood pilocytic astrocytomas metastatic to the leptomeninges with high-dose cyclophosphamide.
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Surgical outcomes of pediatric spinal cord astrocytomas: systematic review and meta-analysis.
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Susceptibility of inbred Fischer rats to brain tumor induction by Rous sarcoma virus.
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Targeted radiotherapy of brain tumours.
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Targeting the Tie2/Tek receptor in astrocytomas.
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Temozolomide and treatment of malignant glioma.
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Temozolomide in early stages of newly diagnosed malignant glioma and neoplastic meningitis.
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Temozolomide in pediatric low-grade glioma.
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Temozolomide-induced flare in high-grade gliomas: a new clinical entity.
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Temporal lobe hypometabolism on PET: predictor of seizure control after temporal lobectomy.
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The Effects of Thermal Preconditioning on Oncogenic and Intraspinal Cord Growth Features of Human Glioma Cells.
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The Preuss Foundation Seminar on vaccine therapy for malignant primary brain tumors. February 15-17, 1998, La Jolla, Calif.
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The evolution of the histology in pleomorphic xanthoastrocytomas in children: a study of 15 cases.
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The fine structure of canine gliomas and intracranial sarcomas induced by the Schmidt-Ruppin strain of the Rous sarcoma virus.
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The fine structure of intracranial neoplasms induced by the inoculation of avian sarcoma virus in neonatal and adult rats.
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The genetic landscape of anaplastic astrocytoma.
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The genetic landscape of gliomas arising after therapeutic radiation.
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The human glutathione S-transferase P1 protein is phosphorylated and its metabolic function enhanced by the Ser/Thr protein kinases, cAMP-dependent protein kinase and protein kinase C, in glioblastoma cells.
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The increasing incidence of malignant gliomas and primary central nervous system lymphoma in the elderly.
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The induction of intractranial neoplasms by the inoculation of avian sarcoma virus in perinatal and adult rats.
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The role of the subependymal plate in avian sarcoma virus brain tumor induction: comparison of incipient tumors in neonatal and adult rats.
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The use of fluorescein sodium in the biopsy and gross-total resection of a tectal plate glioma.
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Transformation of juvenile pilocytic astrocytoma to anaplastic pilocytic astrocytoma in patients with neurofibromatosis type I.
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Tumor angiogenic and hypoxic profiles predict radiographic response and survival in malignant astrocytoma patients treated with bevacizumab and irinotecan.
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Tumor antigens in astrocytic gliomas.
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Tumorigenic cell culture lines from a spontaneous VM/Dk murine astrocytoma (SMA).
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Unusual presentations of inflammatory conditions in cerebrospinal fluid.
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Use of apparent diffusion coefficient values for diagnosis of pediatric posterior fossa tumors.
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Utility of EGFR and PTEN numerical aberrations in the evaluation of diffusely infiltrating astrocytomas. Laboratory investigation.
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Well differentiated astrocytoma occurring nine years after radiation therapy for medulloblastoma.
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Work in progress: [18F] fluorodeoxyglucose and positron emission tomography in the evaluation of radiation necrosis of the brain.
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XRCC3 haplotypes and risk of gliomas in a Chinese population: a hospital-based case-control study.
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Keywords of People
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Erickson, Harold Paul,
Professor Emeritus of Cell Biology,
Cell Biology
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McLendon, Roger Edwin,
Professor of Pathology,
Pathology
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O'Connor, Christopher Michael,
Richard Sean Stack, M.D. Distinguished Professor,
Medicine, Clinical Pharmacology
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Sampson, John Howard,
Robert H., M.D. and Gloria Wilkins Professor of Neurosurgery, in the School of Medicine,
Biomedical Engineering
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Turner, Dennis Alan,
Professor of Neurosurgery,
Biomedical Engineering
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Yan, Hai,
Adjunct Professor of Pathology,
Pathology