Atrophy

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  Subject Areas on Research

  • (18)F-fluorodeoxyglucose positron emission tomography and MR imaging findings in Rasmussen encephalitis. 
  • 5-HTTLPR polymorphism impacts human cingulate-amygdala interactions: a genetic susceptibility mechanism for depression. 
  • A murine model of congenital toxoplasmic retinochoroiditis. 
  • A pattern-oriented approach to splenic imaging in infants and children. 
  • APOE genotype and hippocampal volume change in geriatric depression. 
  • Age-dependent atrophy and microgravity travel: what do they have in common? 
  • Age-dependent reduction of amygdala volume in bipolar disorder. 
  • Age-related delay in visual and auditory evoked responses is mediated by white- and grey-matter differences. 
  • Altered diffusion tensor imaging measurements in aged transgenic Huntington disease rats. 
  • Amygdala volume in late-life depression: relationship with age of onset. 
  • Amylaceous (polyglucosan) bodies in familial cerebral atrophy of early onset. 
  • An Unusual Presentation of CLN3-Associated Batten Disease With Classic Histopathologic and Ultrastructural Findings. 
  • Analysis of Peripapillary Atrophy in Relation to Macular Geographic Atrophy in Age-Related Macular Degeneration. 
  • Anti-Vascular Endothelial Growth Factor Use and Atrophy in Neovascular Age-Related Macular Degeneration: Systematic Literature Review and Expert Opinion. 
  • Anxiety symptoms in amnestic mild cognitive impairment are associated with medial temporal atrophy and predict conversion to Alzheimer disease. 
  • Artificial Urinary Sphincter Cuff Downsizing Improves Continence and Patient Satisfaction in Cases of Sub-cuff Atrophy. 
  • Association Between Anticholinergic Medication Use and Cognition, Brain Metabolism, and Brain Atrophy in Cognitively Normal Older Adults. 
  • Association of Plasma Neurofilament Light With Neurodegeneration in Patients With Alzheimer Disease. 
  • Association of silent lacunar infarct with brain atrophy and cognitive impairment. 
  • Atlas-based hippocampus segmentation in Alzheimer's disease and mild cognitive impairment. 
  • Atrophie blanche. A disorder associated with defective release of tissue plasminogen activator. 
  • Baseline Prostate Atrophy is Associated with Reduced Risk of Prostate Cancer in Men Undergoing Repeat Prostate Biopsy. 
  • Bilaminar interepithelial bodies within fingerprint dystrophy-like changes in bilateral iridocorneal endothelial syndrome. 
  • Brain and retinal atrophy in African-Americans versus Caucasian-Americans with multiple sclerosis: a longitudinal study. 
  • Brain atrophy and cognitive deficits in Cushing's disease. 
  • Brain atrophy rates in first degree relatives at risk for Alzheimer's. 
  • CD4+Thy1- thymocytes with a Th-type 2 cytokine response. 
  • Cardiac phenotype and angiotensin II levels in AT1a, AT1b, and AT2 receptor single, double, and triple knockouts. 
  • Case Series of Urrets-Zavalia Syndrome After Descemet Membrane Endothelial Keratoplasty. 
  • Cerebral atrophy in an infant following treatment with ifosfamide. 
  • Cerebral volume loss, cognitive deficit and neuropsychological performance: comparative measures of brain atrophy: I. Dementia. 
  • Change in hippocampal volume on magnetic resonance imaging and cognitive decline among older depressed and nondepressed subjects in the neurocognitive outcomes of depression in the elderly study. 
  • Changes in Urinary Microbiome Populations Correlate in Kidney Transplants With Interstitial Fibrosis and Tubular Atrophy Documented in Early Surveillance Biopsies. 
  • Characteristics and appearance of the normal optic nerve head in 6-year-old children. 
  • Chemical evidence for early but unsustained growth in the obstructed mouse kidney. 
  • Choroidal thickness and high myopia: a case-control study of young Chinese men in Singapore. 
  • Clinicopathologic studies of eyes that were obtained postmortem from four patients who were enrolled in the submacular surgery trials: SST Report No. 16. 
  • Collapsing glomerulopathy in 19 patients with systemic lupus erythematosus or lupus-like disease. 
  • Comparing rates of retinal nerve fibre layer loss with GDxECC using different methods of visual-field progression. 
  • Complement factor H increases risk for atrophic age-related macular degeneration. 
  • Complex partial seizures and mesial temporal sclerosis: evaluation with fast spin-echo MR imaging. 
  • Complications using intense ultrasound therapy to treat deep dermal facial skin and subcutaneous tissues. 
  • Creutzfeldt-Jakob disease in a pregnant woman with an implanted dura mater graft. 
  • Defective release of tissue plasminogen activator in systemic and cutaneous vasculitis. 
  • Defects of prostate development and reproductive system in the estrogen receptor-alpha null male mice. 
  • Deficiency of asparagine synthetase causes congenital microcephaly and a progressive form of encephalopathy. 
  • Description of the Age-Related Eye Disease Study 9-step severity scale applied to participants in the Complications of Age-related Macular Degeneration Prevention Trial. 
  • Differential associations of cortical and subcortical cerebral atrophy with retinal vascular signs in patients with acute stroke. 
  • Diffuse glaucomatous structural and functional damage in the hemifield without significant pattern loss. 
  • Distinct aspects of frontal lobe structure mediate age-related differences in fluid intelligence and multitasking. 
  • Distribution of OCT Features within Areas of Macular Atrophy or Scar after 2 Years of Anti-VEGF Treatment for Neovascular AMD in CATT. 
  • Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2. 
  • Editorial Comment: Is It Time to Take the "Sub" Out of Subsyndromal Depression? 
  • Educational attainment and hippocampal atrophy in the Alzheimer's disease neuroimaging initiative cohort. 
  • Effect of glutamine-supplemented total parenteral nutrition on recovery of the small intestine after starvation atrophy. 
  • Effect of thymectomy on peripheral lymphocyte subsets in myasthenia gravis: selective effect on T-cells in patients with thymic atrophy. 
  • Effects of chemotherapy and tamoxifen on cervical and vaginal smears in bone marrow transplant recipients. 
  • Effects of indocyanine green on the retina and retinal pigment epithelium in a porcine model of retinal hole. 
  • Fast spin-echo MR in hippocampal sclerosis: correlation with pathology and surgery. 
  • Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE. 
  • Fibrinolytic abnormalities in two different cutaneous manifestations of venous disease. 
  • Functional signature of conversion of patients with mild cognitive impairment. 
  • Global brain volume and N-acetyl-aspartate decline over seven decades of normal aging. 
  • Hanging leg syndrome: combined bilateral femoral and sciatic neuropathies. 
  • Heterogeneity of brain lesions in pediatric traumatic brain injury. 
  • Hippocampal atrophy confounds template-based functional MR imaging measures of hippocampal activation in patients with mild cognitive impairment. 
  • Hippocampal atrophy relates to fluid intelligence decline in the elderly. 
  • Hippocampal volumes and depression subtypes. 
  • Hippocampus atrophy and the longitudinal course of late-life depression. 
  • Homocysteine and Cerebral Atrophy: The Epidemiology of Dementia in Singapore Study. 
  • Idiopathic intracranial hypertension: a case report with optic nerve histopathology. 
  • Immune reconstitution in patients with HIV infection. 
  • Immunological and short-term brain volume changes in relapsing forms of multiple sclerosis treated with interferon beta-1a subcutaneously three times weekly: an open-label two-arm trial. 
  • Impact of APOE in mild cognitive impairment. 
  • Improving the identification of genitourinary syndrome of menopause through the utilization of the Day-to-Day Impact of Vaginal Aging questionnaire. 
  • In the absence of extrinsic signals, nutrient utilization by lymphocytes is insufficient to maintain either cell size or viability. 
  • Incomplete Retinal Pigment Epithelial and Outer Retinal Atrophy in Age-Related Macular Degeneration: Classification of Atrophy Meeting Report 4. 
  • Integrative Genomics Identifies Novel Associations with APOL1 Risk Genotypes in Black NEPTUNE Subjects. 
  • Interuncal distance as a measure of hippocampal atrophy: normative data on axial MR imaging. 
  • Interuncal distance measurements in healthy volunteers and in patients with Alzheimer disease. 
  • Interventions for mild cognitive impairment and Alzheimer disease: new strategies, new hope. 
  • Ipsilateral subcortical atrophy associated with temporal lobectomy. 
  • Is early age-related macular degeneration associated with cerebral MRI changes? The Atherosclerosis Risk in Communities study. 
  • Leptin selectively augments thymopoiesis in leptin deficiency and lipopolysaccharide-induced thymic atrophy. 
  • Leukemia inhibitory factor is a mediator of Escherichia coli lipopolysaccharide-induced acute thymic atrophy. 
  • Leukemia inhibitory factor, oncostatin M, IL-6, and stem cell factor mRNA expression in human thymus increases with age and is associated with thymic atrophy. 
  • Leukoencephalopathy and depression. 
  • Linear subcutaneous fat atrophy after a single corticosteroid injection for ocular adnexal hemangioma. 
  • Longitudinal MRI findings in pyridoxine-dependent seizures. 
  • Longitudinal changes in white matter disease and cognition in the first year of the Alzheimer disease neuroimaging initiative. 
  • Losing neurons: selective vulnerability and mesial temporal sclerosis. 
  • Loss of uteroglobin expression in prostate cancer: relationship to advancing grade. 
  • Luminal epidermal growth factor preserves mucosal mass of small bowel in fasting rats. 
  • MR measurement of normal and pathologic brainstem diameters. 
  • MR of the brain in mitochondrial myopathy. 
  • MRI scans in patients with tardive dyskinesia. 
  • Macular Atrophy in Neovascular Age-Related Macular Degeneration with Monthly versus Treat-and-Extend Ranibizumab: Findings from the TREX-AMD Trial. 
  • Macular Features on Spectral-Domain Optical Coherence Tomography Imaging Associated With Visual Acuity in Coats' Disease. 
  • Macular symmetry testing for glaucoma detection. 
  • Macular translocation with 360 degrees peripheral retinectomy for geographic atrophy. 
  • Magnetic resonance imaging of Alzheimer's disease. 
  • Management of Menopausal Symptoms for Women Who Are at High Risk of Thrombosis. 
  • Mannitol bolus preferentially shrinks non-infarcted brain in patients with ischemic stroke. 
  • Mapping the effect of the apolipoprotein E genotype on 4-year atrophy rates in an Alzheimer disease-related brain network. 
  • Medial versus lateral frontal lobe contributions to voluntary saccade control as revealed by the study of patients with frontal lobe degeneration. 
  • Muscle-specific RING finger 1 is a bona fide ubiquitin ligase that degrades cardiac troponin I. 
  • Natural history of central sparing in geographic atrophy secondary to non-exudative age-related macular degeneration. 
  • Neuroprotective effects of creatine in a transgenic mouse model of Huntington's disease. 
  • Novel missense WFS1 variant causing autosomal dominant atypical Wolfram syndrome. 
  • Occurrence of vascular anomalies in unilateral cerebral hypoplasia. "Cerebral hemiatrophy". 
  • Ocular pathology in rainbow trout in Malawi (Zomba disease). 
  • Ocular toxoplasmosis presenting with focal retinal nerve fiber atrophy simulating glaucoma. 
  • Optical Coherence Tomography Predictors of Risk for Progression to Non-Neovascular Atrophic Age-Related Macular Degeneration. 
  • Optical coherence tomography of choroidal osteoma in 22 cases: evidence for photoreceptor atrophy over the decalcified portion of the tumor. 
  • Oral manifestations of chronic graft-v-host disease. 
  • Orbitofrontal cortex volume in late life depression: influence of hyperintense lesions and genetic polymorphisms. 
  • Outcomes following revisions and secondary implantation of the artificial urinary sphincter. 
  • Oxidative phenotype protects myofibers from pathological insults induced by chronic heart failure in mice. 
  • PTH/PTHrP Receptor Mediates Cachexia in Models of Kidney Failure and Cancer. 
  • Parkinson plus syndrome: diagnosis using high field MR imaging of brain iron. 
  • Parry-Romberg syndrome with fatal brain stem involvement. 
  • Peripapillary chorioretinal atrophy: Bruch's membrane changes and photoreceptor loss. 
  • Pigmented paravenous retinochoroidal atrophy. Discordant expression in monozygotic twins. 
  • Predictive Utility of Marketed Volumetric Software Tools in Subjects at Risk for Alzheimer Disease: Do Regions Outside the Hippocampus Matter? 
  • Prevalence and Progression of Macular Atrophy in Eyes with Neovascular Age-Related Macular Degeneration in the Phase 2 Ladder Trial of the Port Delivery System with Ranibizumab. 
  • Prevalence of Meibomian Gland Atrophy in a Pediatric Population. 
  • Purkinje cell loss in experimental autoimmune encephalomyelitis. 
  • Quantitative cerebral anatomy in depression. A controlled magnetic resonance imaging study. 
  • Quantitative cerebral anatomy of the aging human brain: a cross-sectional study using magnetic resonance imaging. 
  • Randomized trial of pallidotomy versus medical therapy for Parkinson's disease. 
  • Recurrence of retinal pigment epithelial changes after macular translocation with 360 degrees peripheral retinectomy for geographic atrophy. 
  • Reduced growth, abnormal kidney structure, and type 2 (AT2) angiotensin receptor-mediated blood pressure regulation in mice lacking both AT1A and AT1B receptors for angiotensin II. 
  • Regional atrophy of the corpus callosum in dementia. 
  • Regionally selective atrophy of subcortical structures in prodromal HD as revealed by statistical shape analysis. 
  • Relationship of medial temporal lobe atrophy, APOE genotype, and cognitive reserve in preclinical Alzheimer's disease. 
  • Religious factors and hippocampal atrophy in late life. 
  • Remote sites of structural atrophy predict later amyloid formation in a mouse model of Alzheimer's disease. 
  • Renal growth and development in mice lacking AT1A receptors for angiotensin II. 
  • Retinal atrophy in eyes with resolved papilledema detected by optical coherence tomography. 
  • Retinal microvascular signs and 10-year risk of cerebral atrophy: the Atherosclerosis Risk in Communities (ARIC) study. 
  • Retinal neurodegeneration on optical coherence tomography and cerebral atrophy. 
  • Retinal pigment epithelial degeneration, partial retinal atrophy and macular hole in acute lymphocytic leukemia. 
  • Role of white matter lesions, cerebral atrophy, and APOE on cognition in older persons with and without dementia: the Cache County, Utah, study of memory and aging. 
  • Sel1L is indispensable for mammalian endoplasmic reticulum-associated degradation, endoplasmic reticulum homeostasis, and survival. 
  • Severe subcutaneous hemiatrophy following treatment of Wilms' tumor: CT demonstration. 
  • Skeletal muscle mass recovery from atrophy in IL-6 knockout mice. 
  • Sonography of an intratesticular lipoma. 
  • Spatial patterns of brain amyloid-beta burden and atrophy rate associations in mild cognitive impairment. 
  • Spectral domain optical coherence tomography imaging of geographic atrophy margins. 
  • Spectral-Domain OCT-Based Prevalence and Progression of Macular Atrophy in the HARBOR Study for Neovascular Age-Related Macular Degeneration. 
  • Statin use and hippocampal volumes in elderly subjects at risk for Alzheimer's disease: a pilot observational study. 
  • Subcortical Atrophy in Cognitive Impairment and Dementia. 
  • Subcortical brain anatomy in anorexia and bulimia. 
  • Subfoveal choroidal thickness predicts macular atrophy in age-related macular degeneration: results from the TREX-AMD trial. 
  • T cell homeostasis requires G protein-coupled receptor-mediated access to trophic signals that promote growth and inhibit chemotaxis. 
  • T cell receptor excision circle assessment of thymopoiesis in aging mice. 
  • Tau-knockout mice show reduced GSK3-induced hippocampal degeneration and learning deficits. 
  • Temporal bone findings in a case of Susac's syndrome. 
  • The CERAD experience, Part VIII: Neuroimaging-neuropathology correlates of temporal lobe changes in Alzheimer's disease. 
  • The Chédiak-Higashi syndrome: CT and MR findings. 
  • The Haw River syndrome: dentatorubropallidoluysian atrophy (DRPLA) in an African-American family. 
  • The fornix provides multiple biomarkers to characterize circuit disruption in a mouse model of Alzheimer's disease. 
  • The moderating effect of the APOE [small element of] 4 allele on the relationship between hippocampal volume and cognitive decline in older depressed patients. 
  • Three-dimensional patterns of hippocampal atrophy in mild cognitive impairment. 
  • Tongue weakness and atrophy differentiates late-onset Pompe disease from other forms of acquired/hereditary myopathy. 
  • Topographic Correspondence of Macular Atrophy With Choroidal Neovascularization in Ranibizumab-treated Eyes of the TREX-AMD Trial. 
  • Tracking brain volume changes in C57BL/6J and ApoE-deficient mice in a model of neurodegeneration: a 5-week longitudinal micro-MRI study. 
  • Transcorporal artificial urinary sphincter cuff placement in cases requiring revision for erosion and urethral atrophy. 
  • Treatment of urticaria pigmentosa with corticosteroids. 
  • Type 2 diabetes mellitus, brain atrophy, and cognitive decline. 
  • Uniocular vascular occlusion in a paraplegic hybrid monkey. A clinicopathologic study. 
  • Unique Primary Care Needs of Transgender and Gender Non-Binary People. 
  • VALIDATION OF A DEEP LEARNING-BASED ALGORITHM FOR SEGMENTATION OF THE ELLIPSOID ZONE ON OPTICAL COHERENCE TOMOGRAPHY IMAGES OF AN USH2A-RELATED RETINAL DEGENERATION CLINICAL TRIAL. 
  • Vaginal administration of low-dose conjugated estrogens: systemic absorption and effects on the endometrium. 
  • Venous leg ulcers: an analysis of underlying venous disease. 
  • Ventilatory muscles and mechanical ventilatory support. 
  • Ventricular enlargement in poor-outcome schizophrenia. 
  • Weighted least-squares approach for comparing correlated kappa. 
  • What constitutes clinical evidence for neuroprotection in Alzheimer disease: support for the cholinesterase inhibitors? 
  • White matter hyperintensity on magnetic resonance imaging: clinical and neuroanatomic correlates in the depressed elderly. 
  • White matter lesions detected by magnetic resonance imaging after radiotherapy and high-dose chemotherapy in children with medulloblastoma or primitive neuroectodermal tumor. 
  • Whole brain neuronal abnormalities in focal epilepsy quantified with proton MR spectroscopy. 
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  Keywords of People

  • Bowes Rickman, Catherine, George and Geneva Boguslavsky Distinguished Professor of Eye Research, Cell Biology
  • Charles, Hal Cecil, Adjunct Associate Professor in the Department of Radiology, Radiology
  • Mruthyunjaya, Prithvi, Adjunct Associate Professor in the Department of Ophthalmology, Ophthalmology, Vitreoretinal Diseases & Surgery
  • Roy Choudhury, Kingshuk, Adjunct Associate Professor in the Department of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics
  • Stinnett, Sandra Sue, Associate Professor of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics
  • Toth, Cynthia Ann, Joseph A.C. Wadsworth Distinguished Professor of Ophthalmology, Biomedical Engineering