Autoantibodies

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  Subject Areas on Research

  • 'Minimal symptom expression' in patients with acetylcholine receptor antibody-positive refractory generalized myasthenia gravis treated with eculizumab. 
  • 14th International Congress on Antiphospholipid Antibodies Task Force. Report on antiphospholipid syndrome laboratory diagnostics and trends. 
  • 60-kDa Ro protein autoepitopes identified using recombinant polypeptides. 
  • 9G4 autoreactivity is increased in HIV-infected patients and correlates with HIV broadly neutralizing serum activity. 
  • A 9-yr evaluation of carrier erythrocyte encapsulated adenosine deaminase (ADA) therapy in a patient with adult-type ADA deficiency. 
  • A Path to Prediction of Outcomes in Juvenile Idiopathic Inflammatory Myopathy. 
  • A T cell intrinsic role of Id3 in a mouse model for primary Sjogren's syndrome. 
  • A Therapeutic Antibody for Cancer, Derived from Single Human B Cells. 
  • A defect in the humoral immune response to protein antigens and haptens in immunoglobulin mu heavy-chain transgenic mice. 
  • A dietary pattern that lowers oxidative stress increases antibodies to oxidized LDL: results from a randomized controlled feeding study. 
  • A human anti-HIV autoantibody enhances EBV transformation and HIV infection. 
  • A molecular basis for MHC class II--associated autoimmunity. 
  • A multicenter trial of recombinant human interferon gamma in patients with systemic sclerosis: effects on cutaneous fibrosis and interleukin 2 receptor levels. 
  • A murine Ig light chain transgene reveals IGKV3 gene contributions to anti-collagen types IV and II specificities. 
  • A new method for the cytological analysis of autoantibody specificities using whole-mount, surface-spread meiotic nuclei. 
  • A novel antineuronal antibody in a motor neuron syndrome associated with breast cancer. 
  • A pathogenetic role for TNF alpha in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency. 
  • A prospective study measuring the development of antibodies against platelet factor 4-heparin in healthy males after exposure to heparins. 
  • A prospective study of antineutrophil cytoplasmic antibody (c-ANCA) and clinical criteria in diagnosing Wegener's granulomatosis. 
  • A randomized controlled trial of methotrexate for patients with generalized myasthenia gravis. 
  • A sequence-specific conformational epitope on U1 RNA is recognized by a unique autoantibody. 
  • A simple enzyme-linked immunosorbent assay for antibodies to native DNA. 
  • AAEE minimonograph #25: Single-fiber electromyography in myasthenia gravis. 
  • ANCA--the rheumatologist's perspective 1992. 
  • ASH evidence-based guidelines: is the IgG-specific anti-PF4/heparin ELISA superior to the polyspecific ELISA in the laboratory diagnosis of HIT? 
  • Aberrant monocyte prostaglandin synthase 2 (PGS2) expression in type 1 diabetes before and after disease onset. 
  • Acetylcholine receptor antibodies in juvenile myasthenia gravis. 
  • Acetylcholine receptor antibody measurements in acquired myasthenia gravis. Diagnostic sensitivity and predictive value for thymoma. 
  • Acquired angioedema in B cell lymphoproliferative disease: A retrospective case series. 
  • Acquired myasthenia gravis. 
  • Activation-induced cytidine deaminase mediates central tolerance in B cells. 
  • Adaptive immune response to therapy in hmgcr autoantibody myopathy. 
  • Advances in autoimmune myasthenia gravis management. 
  • Agonistic angiotensin II type 1 receptor autoantibodies in postpartum women with a history of preeclampsia. 
  • Alloimmunization in sickle cell disease: changing antibody specificities and association with chronic pain and decreased survival. 
  • Alteration of human erythrocyte membrane properties by complement fixation. 
  • Altered toll-like receptor responsiveness underlies a dominant heritable defect in B cell tolerance in autoimmune New Zealand Black mice. 
  • Alu RNA-protein complexes formed in vitro react with a novel lupus autoantibody. 
  • Amplified B lymphocyte CD40 signaling drives regulatory B10 cell expansion in mice. 
  • An auto-anti-M causing hemolysis in vitro. 
  • An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1. 
  • Analysis of autoantibodies to plasminogen in the serum of patients with rheumatoid arthritis. 
  • Analysis of autoantibody binding to different regions of the human La antigen expressed in recombinant fusion proteins. 
  • Analysis of the expression of CD5 by human B cells and correlation with functional activity. 
  • Anaphylactic reactions after gamma globulin administration in patients with hypogammaglobulinemia. Detection of IgE antibodies to IgA. 
  • Anaphylaxis after administration of gamma globulin for hypogammaglobulinemia. 
  • Angiotensin II Type 1 receptor antibodies are associated with inflammatory cytokines and poor clinical outcomes in pediatric kidney transplantation. 
  • Antagonism of the Neonatal Fc Receptor as an Emerging Treatment for Myasthenia Gravis. 
  • Anti-Angiotensin II Type 1 Receptor and Anti-Endothelial Cell Antibodies: A Cross-Sectional Analysis of Pathological Findings in Allograft Biopsies. 
  • Anti-Cortactin Autoantibodies Are Associated With Key Clinical Features in Adult Myositis But Are Rarely Present in Juvenile Myositis. 
  • Anti-DNA and autoantibodies. 
  • Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation. 
  • Anti-FHL1 autoantibodies in juvenile myositis are associated with anti-Ro52 autoantibodies but not with severe disease features. 
  • Anti-GAD antibodies in Chinese patients with youth and adult-onset IDDM and NIDDM. 
  • Anti-Interleukin-6 Antibodies for Autoimmune Retinopathy with Macular Edema. 
  • Anti-Jo-1 syndrome presenting as cryptogenic organizing pneumonia. 
  • Anti-La antibody production by MRL-1pr/1pr mice. Analysis of fine specificity. 
  • Anti-MuSK antibody myasthenia gravis: clinical findings and response to treatment in two large cohorts. 
  • Anti-Myelin Oligodendrocyte Glycoprotein Optic Neuritis or Neuroretinitis? 
  • Anti-Sm autoantibodies in MRL mice: analysis of precursor frequency. 
  • Anti-Yo antibody-mediated paraneoplastic cerebellar degeneration associated with cognitive affective syndrome in a patient with breast cancer: a case report and literature review. 
  • Anti-beta(1)-adrenergic receptor antibodies and heart failure: causation, not just correlation. 
  • Anti-beta(2)-glycoprotein I antibody-mediated inhibition of activated protein C requires binding of beta(2)-glycoprotein I to phospholipids. 
  • Anti-heparin/platelet factor 4 antibody optical density values and the confirmatory procedure in the diagnosis of heparin-induced thrombocytopenia. 
  • Anti-laminin reactivity and glomerular immune deposition by in vitro recombinant antibodies. 
  • Anti-sm autoantibodies in systemic lupus target highly basic surface structures of complexed spliceosomal autoantigens. 
  • Anti-tumor necrosis factor-alpha therapy augments dipeptidyl peptidase IV activity and decreases autoantibodies to GRP78/BIP and phosphoglucose isomerase in patients with rheumatoid arthritis. 
  • Antibodies against the voltage-dependent anion channel (VDAC) and its protective ligand hexokinase-I in children with autism. 
  • Antibodies from patients with heparin-induced thrombocytopenia stimulate monocytic cells to express tissue factor and secrete interleukin-8. 
  • Antibodies to CD45 and other cell membrane antigens in systemic lupus erythematosus. 
  • Antibodies to DNA: infection or genetics? 
  • Antibodies to granulocyte precursors in selective myeloid hypoplasia and other suspected autoimmune neutropenias: use of HL-60 cells as targets. 
  • Antibodies to the GABA(B) receptor in limbic encephalitis with seizures: case series and characterisation of the antigen. 
  • Antibody-induced proteinase activation: a proposed mechanism for pemphigus. 
  • Antiendothelial cell antibodies in patients with Wegener's granulomatosis: prevalence and correlation with disease activity and manifestations. 
  • Antihuman factor V antibodies after use of relatively pure bovine thrombin. 
  • Antiphospholipid antibodies and recurrent pregnancy loss. 
  • Antiphospholipid syndrome: advances in diagnosis, pathogenesis, and management. 
  • Antithrombotic therapy in heparin-induced thrombocytopenia: guidelines translated for the clinician. 
  • Antitumor Immune Mechanisms of the Anti-Complement Factor H Antibody GT103. 
  • Are autoantibodies the targets of B-cell-directed therapy? 
  • Assessment of autoantibodies to meningioma in a population-based study. 
  • Association between cell-mediated demyelination and astrocyte stimulation. 
  • Association of Anti-3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Autoantibodies With DRB1*07:01 and Severe Myositis in Juvenile Myositis Patients. 
  • Association of serum B-cell activating factor level and proportion of memory and transitional B cells with clinical response after rituximab treatment of bullous pemphigoid patients. 
  • At this junction…. 
  • Auto-anti-M causing immune hemolysis in vitro. 
  • Auto-antibodies to p53 and the Subsequent Development of Colorectal Cancer in a U.S. Prospective Cohort Consortium. 
  • Autoantibodies against cell surface GRP78 promote tumor growth in a murine model of melanoma. 
  • Autoantibodies against the cell surface-associated chaperone GRP78 stimulate tumor growth via tissue factor. 
  • Autoantibodies and their idiotypes. 
  • Autoantibodies and their idiotypes. 
  • Autoantibodies and their significance. 
  • Autoantibodies specific for U1 RNA and initiator methionine tRNA. 
  • Autoantibodies to DEK oncoprotein in human inflammatory disease. 
  • Autoantibodies to Dense Fine Speckles in Pediatric Diseases and Controls. 
  • Autoantibodies to glutamate receptor GluR3 in Rasmussen's encephalitis. 
  • Autoantibodies to the GLUT-2 glucose transporter of beta cells in insulin-dependent diabetes mellitus of recent onset. 
  • Autoantibodies to the alpha/beta T-cell receptors in human immunodeficiency virus infection: dysregulation and mimicry. 
  • Autoantibody biomarkers identified by proteomics methods distinguish ovarian cancer from non-ovarian cancer with various CA-125 levels. 
  • Autoantibody levels in myositis patients correlate with clinical response during B cell depletion with rituximab. 
  • Autoimmune epitopes in messenger RNA. 
  • Autoimmune retinopathy and antiretinal antibodies: a review. 
  • Autoimmunity to munc-18 in Rasmussen's encephalitis. 
  • Autoreactive B cells recruited to lungs by silica exposure contribute to local autoantibody production in autoimmune-prone BXSB and B cell receptor transgenic mice. 
  • Autoregulation of Tcr V region epitopes in autoimmune disease. 
  • B Lymphocyte signaling established by the CD19/CD22 loop regulates autoimmunity in the tight-skin mouse. 
  • B cell depletion delays collagen-induced arthritis in mice: arthritis induction requires synergy between humoral and cell-mediated immunity. 
  • B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies. 
  • B-lymphocyte depletion reduces skin fibrosis and autoimmunity in the tight-skin mouse model for systemic sclerosis. 
  • BAFF expression correlates with idiopathic inflammatory myopathy disease activity measures and autoantibodies. 
  • BAFF-ling autoantibodies. 
  • Basement membranes and autoimmune diseases. 
  • Beta2-glycoprotein I-dependent anticardiolipin antibodies preferentially bind the amino terminal domain of beta2-glycoprotein I. 
  • Binding of anti-GRP78 autoantibodies to cell surface GRP78 increases tissue factor procoagulant activity via the release of calcium from endoplasmic reticulum stores. 
  • Biologic predictors of clinical improvement in rituximab-treated refractory myositis. 
  • Bone loss, pain and inflammation: three faces of ACPA in RA pathogenesis. 
  • Brief Report: The Genetic Profile of Rheumatoid Factor-Positive Polyarticular Juvenile Idiopathic Arthritis Resembles That of Adult Rheumatoid Arthritis. 
  • CD19 regulates skin and lung fibrosis via Toll-like receptor signaling in a model of bleomycin-induced scleroderma. 
  • CD19-regulated signaling thresholds control peripheral tolerance and autoantibody production in B lymphocytes. 
  • CD5+ B lymphocytes in high-risk islet cell antibody-positive and newly diagnosed IDDM subjects. 
  • Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies. 
  • Cartilage-binding antibodies induce pain through immune complex-mediated activation of neurons. 
  • Central tolerance regulates B cells reactive with Goodpasture antigen alpha3(IV)NC1 collagen. 
  • Changes in oligosaccharide chains of autoantibodies to GRP78 expressed during progression of malignant melanoma stimulate melanoma cell growth and survival. 
  • Changing concepts in pathophysiology of the vasculitides. 
  • Chaperones and disease. 
  • Characterising the autoantibody repertoire in systemic sclerosis following myeloablative haematopoietic stem cell transplantation. 
  • Characterization and idiotypic analysis of an anti-RNP monoclonal antibody. 
  • Characterization of a murine monoclonal antibody that mimics heparin-induced thrombocytopenia antibodies. 
  • Characterization of autoantibodies in pemphigus using antigen-specific enzyme-linked immunosorbent assays with baculovirus-expressed recombinant desmogleins. 
  • Characterization of human serum dipeptidyl peptidase IV (CD26) and analysis of its autoantibodies in patients with rheumatoid arthritis and other autoimmune diseases. 
  • Chimeric anti-tumor necrosis factor-alpha monoclonal antibody treatment of patients with rheumatoid arthritis receiving methotrexate therapy. 
  • Chronic cicatrizing conjunctivitis in a patient with epidermolysis bullosa acquisita. 
  • Chronic graft-versus-host syndrome in man. A long-term clinicopathologic study of 20 Seattle patients. 
  • Circulating microRNA plasma profile in MuSK+ myasthenia gravis. 
  • Clinical Implications of Direct Immunofluorescence Findings in Patients With Ocular Mucous Membrane Pemphigoid. 
  • Clinical and laboratory manifestations of anti-factor V antibodies. 
  • Clinical approach to the diagnosis of autoimmune encephalitis in the pediatric patient. 
  • Clinical aspects of MuSK antibody positive seronegative MG. 
  • Clinical criteria for systemic lupus erythematosus precede diagnosis, and associated autoantibodies are present before clinical symptoms. 
  • Clinical features of myasthenia gravis. 
  • Clinical outcomes in a cohort of patients with heparin-induced thrombocytopenia. 
  • Clinicoserological insights into patients with immune checkpoint inhibitor-induced myasthenia gravis. 
  • Cold Agglutinin Autoantibodies in a Patient without a Visible Coronary Sinus Ostium: Strategies for Myocardial Protection without Using Retrograde Cardioplegia. 
  • Comment: Is 3,4-DAP a new option in treating MuSK MG? 
  • Comparative epitope mapping of sera from United States (US) and Japanese patients with bullous pemphigoid (BP) to fusion proteins encoded by BPAG1. 
  • Complement Factor H Antibodies from Lung Cancer Patients Induce Complement-Dependent Lysis of Tumor Cells, Suggesting a Novel Immunotherapeutic Strategy. 
  • Complement factor H autoantibodies are associated with early stage NSCLC. 
  • Correction of hypoprothrombinemia by immunosuppressive treatment of the lupus anticoagulant-hypoprothrombinemia syndrome. 
  • Correlation of IgG autoantibodies against acetylcholine receptors and desmogleins in patients with pemphigus treated with steroid sparing agents or rituximab. 
  • Critical role for mouse marginal zone B cells in PF4/heparin antibody production. 
  • Cross-reactive idiotypes in the sera of patients with bullous pemphigoid express anti-basement-membrane-zone activity. 
  • Cryptococcus deuterogattii VGIIa Infection Associated with Travel to the Pacific Northwest Outbreak Region in an Anti-Granulocyte-Macrophage Colony-Stimulating Factor Autoantibody-Positive Patient in the United States. 
  • Cryptococcus gattii Species Complex as an Opportunistic Pathogen: Underlying Medical Conditions Associated with the Infection. 
  • DEK in the synovium of patients with juvenile idiopathic arthritis: characterization of DEK antibodies and posttranslational modification of the DEK autoantigen. 
  • DEK is a poly(ADP-ribose) acceptor in apoptosis and mediates resistance to genotoxic stress. 
  • Decreased expression levels of CD22 and L-selectin on peripheral blood B lymphocytes from patients with bullous pemphigoid. 
  • Deficiency of 5-lipoxygenase abolishes sex-related survival differences in MRL-lpr/lpr mice. 
  • Delayed onset adenosine deaminase deficiency associated with acute disseminated encephalomyelitis. 
  • Development of autoantibodies before the clinical onset of systemic lupus erythematosus. 
  • Development of pemphigus vulgaris-like lesions in severe combined immunodeficiency disease mice reconstituted with lymphocytes from patients. 
  • Developments in the scientific understanding of lupus. 
  • Differential extraction and enrichment of human sperm surface proteins in a proteome: identification of immunocontraceptive candidates. 
  • Differential immunoglobulin class-mediated responses to components of the U1 small nuclear ribonucleoprotein particle in systemic lupus erythematosus and mixed connective tissue disease. 
  • Dilated cardiomyopathy in isolated congenital complete atrioventricular block: early and long-term risk in children. 
  • Distinct specificity and single-molecule kinetics characterize the interaction of pathogenic and non-pathogenic antibodies against platelet factor 4-heparin complexes with platelet factor 4. 
  • Do acetylcholine receptor and striated muscle antibodies predict the presence of thymoma in patients with myasthenia gravis? 
  • Does change in acetylcholine receptor antibody level correlate with clinical change in myasthenia gravis? 
  • Does change in neuromuscular jitter predict or correlate with clinical change in MG? 
  • Dominant gain-of-function STAT1 mutations in FOXP3 wild-type immune dysregulation-polyendocrinopathy-enteropathy-X-linked-like syndrome. 
  • Dystrophin immunity in Duchenne's muscular dystrophy. 
  • Effect of anti-CD4 antibody treatment on inflammatory arthritis in MRL-lpr/lpr mice. 
  • Effect of sex on the induction of anti-DNA antibodies in normal mice immunized with bacterial DNA. 
  • Effect of therapeutic plasma exchange on immunoglobulins in myasthenia gravis. 
  • Effect os xid on anti-DNA B-cell precursors. 
  • Endocrinology and recurrent early pregnancy loss. 
  • Endogenous IL-12 is required for induction and expression of experimental autoimmune uveitis. 
  • Enhanced Th17-cell responses render CCR2-deficient mice more susceptible for autoimmune arthritis. 
  • Enrichment of malondialdehyde-acetaldehyde antibody in the rheumatoid arthritis joint. 
  • Eosinophils Mediate Tissue Injury in the Autoimmune Skin Disease Bullous Pemphigoid. 
  • Epidemiological evidence for a hereditary contribution to myasthenia gravis: a retrospective cohort study of patients from North America. 
  • Epidemiology, diagnostics, and biomarkers of autoimmune neuromuscular junction disorders. 
  • Epitope mapping of the U1 small nuclear ribonucleoprotein particle in patients with systemic lupus erythematosus and mixed connective tissue disease. 
  • Evaluation and Management of Autoimmune Encephalitis: A Clinical Overview for the Practicing Child Psychiatrist. 
  • Evaluation of microarray surfaces and arraying parameters for autoantibody profiling. 
  • Evidence-based management of bullous pemphigoid. 
  • Evolving story of autoantibodies in systemic lupus erythematosus. 
  • Exposure of mice to topical bovine thrombin induces systemic autoimmunity. 
  • Expression of IgM and IgG autoantibodies in pediatric and adult systemic lupus erythematosus. 
  • Expression of autoantibodies to recombinant (U1) RNP-associated 70K antigen in systemic lupus erythematosus. 
  • Failure of splenectomy in Felty's syndrome. The role of antibodies supporting granulocyte lysis by lymphocytes. 
  • Features of Autoimmune Hepatitis in Patients With Drug-induced Liver Injury. 
  • Focused HLA analysis in Caucasians with myositis identifies significant associations with autoantibody subgroups. 
  • Frequency of celiac disease in individuals with Down syndrome in the United States. 
  • Frequency-specific association of antibodies against heat shock proteins 60 and 70 with noise-induced hearing loss in Chinese workers. 
  • Fulfilling Koch's postulates of autoimmunity: anti-NR2 antibodies in mice and men. 
  • Functional alterations of macrophages in autoimmune MRL-lpr/lpr mice. 
  • GRP78: a multifunctional receptor on the cell surface. 
  • Gait abnormalities and inflammatory cytokines in an autologous nucleus pulposus model of radiculopathy. 
  • Genetic elimination of α3(IV) collagen fails to rescue anti-collagen B cells. 
  • Genome-wide association study identifies HLA 8.1 ancestral haplotype alleles as major genetic risk factors for myositis phenotypes. 
  • Germinal center formation, immunoglobulin class switching, and autoantibody production driven by "non alpha/beta" T cells. 
  • GluR3 autoantibodies destroy neural cells in a complement-dependent manner modulated by complement regulatory proteins. 
  • Glucose-regulated protein (GRP78) is an important cell surface receptor for viral invasion, cancers, and neurological disorders. 
  • Glutamate receptor GluR3 antibodies and death of cortical cells. 
  • Glutathione S-transferase M null homozygosity and risk of systemic lupus erythematosus associated with sun exposure: a possible gene-environment interaction for autoimmunity. 
  • Granzyme B is dispensable for immunologic tolerance to self in a murine model of systemic lupus erythematosus. 
  • HIT and run: heparin's unusual immune response. 
  • HIV-1 autoreactive antibodies: are they good or bad for HIV-1 prevention? 
  • HIV-1 envelope gp41 broadly neutralizing antibodies: hurdles for vaccine development. 
  • HLA polymorphisms in African Americans with idiopathic inflammatory myopathy: allelic profiles distinguish patients with different clinical phenotypes and myositis autoantibodies. 
  • Heavy and light chain utilization in autoantibodies of elderly patients with systemic lupus erythematosus. 
  • Hemorrhage and thrombus formation in early experimental osteonecrosis. 
  • Heparin modifies the immunogenicity of positively charged proteins. 
  • Heparin-associated antiplatelet antibodies increase morbidity and mortality in hemodialysis patients. 
  • Heparin-induced thrombocytopenia, a prothrombotic disease. 
  • Heparin-induced thrombocytopenia. 
  • Heparin-induced thrombocytopenia. 
  • Heparin-induced thrombocytopenia: research and clinical updates. 
  • Heparin-induced thrombocytopenia: when a low platelet count is a mandate for anticoagulation. 
  • Heterogeneous neutralizing antibody and antibody-dependent cell cytotoxicity responses in HIV-1 elite controllers. 
  • Histopathologic changes in anti-angiotensin II type 1 receptor antibody-positive kidney transplant recipients with acute rejection and no donor specific HLA antibodies. 
  • Hodgkin's disease treated with neck radiation is associated with increased antibody-dependent cellular cytotoxicity against human extraocular muscle cells. 
  • How the gut inflames the joints. 
  • Humoral autoimmunity in mice overexpressing B cell surface CD19: vital role for MHC class II. 
  • Hybridoma SLE autoantibodies: insights for the pathogenesis of autoimmune disease. 
  • Hydroxychloroquine sulfate treatment is associated with later onset of systemic lupus erythematosus. 
  • Hyper-Ia antigen expression on B cells from B6-lpr/lpr mice correlates with manifestations of the autoimmune state. 
  • IFN-beta1a inhibits the secretion of Th17-polarizing cytokines in human dendritic cells via TLR7 up-regulation. 
  • IL-4-STAT6 signal transduction-dependent induction of the clinical phase of Sjögren's syndrome-like disease of the nonobese diabetic mouse. 
  • Identification of potential cytokine pathways for therapeutic intervention in murine primary biliary cirrhosis. 
  • Idiotypic analysis of a monoclonal anti-Sm antibody. 
  • Idiotypic cross-reaction between MRL autoantibodies and a BALB/c myeloma. 
  • Idiotypic cross-reaction between MRL monoclonal autoantibodies with different antigen specificity. 
  • IgA antibodies against reticulin and endomysium in the serum and gastrointestinal secretions of patients with dermatitis herpetiformis. 
  • IgG antibody response to polyethylene glycol-modified adenosine deaminase in patients with adenosine deaminase deficiency. 
  • IgG antinuclear antibodies with cross-reactive rheumatoid factor activity. 
  • IgG autoantibodies to "switch peptide" determinants of TCR alpha/beta in human pregnancy. 
  • Imbalance in T follicular helper cells producing IL-17 promotes pro-inflammatory responses in MuSK antibody positive myasthenia gravis. 
  • Immune phenotypes in individuals positive for antinuclear antibodies: The impact of race and ethnicity. 
  • Immunoglobulin (Ig)M antibodies to proteinase 3 in granulomatosis with polyangiitis and microscopic polyangiitis. 
  • Immunohistochemistry for immunoglobulin G4 on paraffin sections for the diagnosis of pemphigus. 
  • Immunolocalization of CENP-A suggests a distinct nucleosome structure at the inner kinetochore plate of active centromeres. 
  • Immunologic consequences of nucleic acid therapy. 
  • Immunopathogenesis of juvenile dermatomyositis. 
  • Immunotherapy using unconjugated CD19 monoclonal antibodies in animal models for B lymphocyte malignancies and autoimmune disease. 
  • Impaired beta-cell function, incretin effect, and glucagon suppression in patients with type 1 diabetes who have normal fasting glucose. 
  • In vitro RNA selection of an autoimmune epitope on stem-loop II of U1 RNA. 
  • In vitro selection of an RNA epitope immunologically cross-reactive with a peptide. 
  • In vitro studies of acantholysis of keratinocytes induced by pemphigus antibody. 
  • Incidence and early outcomes associated with pre-transplant antivimentin antibodies in the cardiac transplantation population. 
  • Increased leptin levels correlate with thyroid autoantibodies in nonobese males. 
  • Independent expression of autoantibodies in systemic lupus erythematosus. 
  • Induction of cross-reactive anti-dsDNA antibodies in preautoimmune NZB/NZW mice by immunization with bacterial DNA. 
  • Infection with Mycobacterium bovis BCG diverts traffic of myelin oligodendroglial glycoprotein autoantigen-specific T cells away from the central nervous system and ameliorates experimental autoimmune encephalomyelitis. 
  • Influence of assay conditions on ELISA determinations of anti-DNA antibodies. 
  • Inhibition of NF-kappaB1 and NF-kappaB2 activation in prostate cancer cells treated with antibody against the carboxyl terminal domain of GRP78: effect of p53 upregulation. 
  • Inhibition of in vitro anti-DNA B-cell responses by cyclosporine. 
  • Inhibition of the transcription factor ROR-γ reduces pathogenic Th17 cells in acetylcholine receptor antibody positive myasthenia gravis. 
  • Inhibitory anti-factor V antibodies bind to the factor V C2 domain and are associated with hemorrhagic manifestations. 
  • Intercellular adhesion molecule-1 deficiency prolongs survival and protects against the development of pulmonary inflammation during murine lupus. 
  • Involvement of urokinase-type plasminogen activator in acantholysis induced by pemphigus IgG. 
  • Ipr gene control of the anti-DNA antibody response. 
  • Is a third-trimester antibody screen in Rh+ women necessary? 
  • Isolation and analysis of cDNA clones expressing human lupus La antigen. 
  • Isolation and characterization of an acquired antithrombin antibody. 
  • Isolation of a nuclease-resistant decoy RNA that can protect human acetylcholine receptors from myasthenic antibodies. 
  • Isolation of a nuclease-resistant decoy RNA that selectively blocks autoantibody binding to insulin receptors on human lymphocytes. 
  • Juvenile dermatomyositis: advances in clinical presentation, myositis-specific antibodies and treatment. 
  • Kappa editing rescues autoreactive B cells destined for deletion in mice transgenic for a dual specific anti-laminin Ig. 
  • Lack of galectin-1 or galectin-3 alters B cell deletion and anergy in an autoantibody transgene model. 
  • Lack of requirement of osteopontin for inflammation, bone erosion, and cartilage damage in the K/BxN model of autoantibody-mediated arthritis. 
  • Lambert-Eaton myasthenic syndrome (LEMS). Clinical and electrodiagnostic features and response to therapy in 59 patients. 
  • Lambert-Eaton myasthenic syndrome: the lack of short-term in vitro effects of serum factors on neuromuscular transmission. 
  • Liposarcoma presenting as an intraluminal ureteral mass. 
  • Low-Avidity Autoantibodies against Bactericidal/Permeability-Increasing Protein Occur in Gram-Negative and Gram-Positive Bacteremia. 
  • Lupus autoantibodies interact directly with distinct glomerular and vascular cell surface antigens. 
  • Lupus autoantibodies recognize the product of an alternative open reading frame of SmB/B'. 
  • Lupus nephritis: update on pathogenesis and disease mechanisms. 
  • Lupus-like nephrotropic autoantibodies in non-autoimmune mice harboring an anti-basement membrane/anti-DNA Ig heavy chain transgene. 
  • Lupus-specific antiribonucleoprotein B cell tolerance in nonautoimmune mice is maintained by differentiation to B-1 and governed by B cell receptor signaling thresholds. 
  • Lymphadenopathy, splenomegaly, and altered immunoglobulin production in BCL3 transgenic mice. 
  • Management of dermatitis herpetiformis. 
  • Mechanisms of anti-DNA production in human and murine SLE. 
  • Mechanisms of antinuclear antibody production in the rheumatic diseases. 
  • Mechanisms of autoantibody production in autoimmune MRL mice. 
  • Mechanisms of polyclonal B-cell activation in autoimmune B6-lpr/lpr mice. 
  • Metabolomics analysis identifies a lipidomic profile in treatment-naïve juvenile dermatomyositis patients vs healthy control subjects. 
  • Microparticles as a source of extracellular DNA. 
  • Microparticles as autoantigens: making immune complexes big. 
  • Microparticles in the blood of patients with systemic lupus erythematosus (SLE): phenotypic characterization and clinical associations. 
  • Mitochondria, cell death, and B cell tolerance. 
  • Molecular Docking and Molecular Dynamics (MD) Simulation of Human Anti-Complement Factor H (CFH) Antibody Ab42 and CFH Polypeptide. 
  • Molecular analysis of spontaneous nephrotropic anti-laminin antibodies in an autoimmune MRL-lpr/lpr mouse. 
  • Molecular biology of nuclear autoantigens. 
  • MuSK-antibody positive myasthenia gravis: clinical and electrodiagnostic patterns. 
  • Multiplexed protein array platforms for analysis of autoimmune diseases. 
  • Muscle autoantibodies in myasthenia gravis: beyond diagnosis? 
  • Myasthenia gravis after allogeneic bone marrow transplantation: relationship to chronic graft-versus-host disease. 
  • Myasthenia gravis and Lambert-Eaton myasthenic syndrome. 
  • Mycophenolate mofetil in AChR-antibody-positive myasthenia gravis: outcomes in 102 patients. 
  • Myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease: Presentation and outcomes of adults at a single center. 
  • Neo-epitope tissue transglutaminase autoantibodies as a biomarker of the gluten sensitive skin disease--dermatitis herpetiformis. 
  • Nephritogenic autoantibodies in systemic lupus erythematosus: immunochemical properties, mechanisms of immune deposition, and genetic origins. 
  • Neuromyelitis optica spectrum disorder and myelin oligodendrocyte glycoprotein associated disorder-optic neuritis: a comprehensive review of diagnosis and treatment. 
  • Neuromyelitis optica: Clinical course and potential prognostic indicators. 
  • Neurophysiological challenges in myasthenia gravis associated with MuSK antibodies: a case report. 
  • New developments in Sjögren's syndrome. 
  • New insights into the role of antinuclear antibodies in systemic lupus erythematosus. 
  • Noninvasive markers in the assessment and management of autoimmune liver diseases. 
  • Novel therapeutic approaches for thrombotic thrombocytopenic purpura. 
  • Nuclear localization of autoantibodies. Novel insights into protein translocation and cellular function. 
  • Outcomes of nonsevere relapses in antineutrophil cytoplasmic antibody-associated vasculitis treated with glucocorticoids. 
  • PAD4 is not essential for disease in the K/BxN murine autoantibody-mediated model of arthritis. 
  • PF4/heparin complexes are T cell-dependent antigens. 
  • PF4/heparin-antibody complex induces monocyte tissue factor expression and release of tissue factor positive microparticles by activation of FcγRI. 
  • PFT-alpha inhibits antibody-induced activation of p53 and pro-apoptotic signaling in 1-LN prostate cancer cells. 
  • Pacemaker therapy in isolated congenital complete atrioventricular block. 
  • Pairing of VK and VK gene families in self-reactive antibodies. 
  • Paraneoplastic retinopathy with multiple detachments of the neurosensory retina and autoantibodies against interphotoreceptor retinoid binding protein (IRBP) in cutaneous melanoma. 
  • Paraneoplastic stiff-person syndrome: no tumor progression over 5 years. 
  • Paraneoplastic temporal lobe epilepsy and anti-Yo autoantibody. 
  • Pathogenesis of A⁻β⁺ ketosis-prone diabetes. 
  • Pathogenesis of autoimmunity in pemphigus. 
  • Pathogenic effector functions of ACPA: Where do we stand? 
  • Pathogenicity of human anti-platelet factor 4 (PF4)/heparin in vivo: generation of mouse anti-PF4/heparin and induction of thrombocytopenia by heparin. 
  • Pathophysiology of dermatitis herpetiformis: a model for cutaneous manifestations of gastrointestinal inflammation. 
  • Patterns of autoantibody expression in pediatric and adult systemic lupus erythematosus. 
  • Pediatric GAD-65 Autoimmune Encephalitis: Assessing Clinical Characteristics and Response to Therapy With a Novel Assessment Scale. 
  • Peripheral blood mononuclear cells from patients with bullous pemphigoid have an increased frequency of response to synthetic peptides encoded by BPAG1. 
  • Plasma antibodies against heat shock protein 70 correlate with the incidence and severity of asthma in a Chinese population. 
  • Polyreactivity and autoreactivity among HIV-1 antibodies. 
  • Potential pathogenicity of deglycosylated IgG cross reactive with streptokinase and fibronectin in the serum of patients with rheumatoid arthritis. 
  • Pre-transplant Screening for Non-HLA Antibodies: Who should be Tested? 
  • Precipitins to Candida albicans in chronic mucocutaneous candidiasis studied by crossed immunoelectrophoresis with intermediate gel. Correlation with clinical and immunological findings. 
  • Predictors of clinical improvement in rituximab-treated refractory adult and juvenile dermatomyositis and adult polymyositis. 
  • Presentations and outcomes of interstitial lung disease and the anti-Ro52 autoantibody. 
  • Presynaptic Disorders: Lambert-Eaton Myasthenic Syndrome and Botulism. 
  • Prevalence of celiac disease and gluten sensitivity in the United States clinical antipsychotic trials of intervention effectiveness study population. 
  • Prognostic significance of a complement factor H autoantibody in early stage NSCLC. 
  • Prostate cancer cell proliferation in vitro is modulated by antibodies against glucose-regulated protein 78 isolated from patient serum. 
  • Protective and pathogenic roles for B cells during systemic autoimmunity in NZB/W F1 mice. 
  • Protein microarray signature of autoantibody biomarkers for the early detection of breast cancer. 
  • Pulmonary alveolar proteinosis in workers at an indium processing facility. 
  • Pulmonary involvement in systemic sclerosis: associations with genetic, serologic, sociodemographic, and behavioral factors. 
  • Quantitative genetic variation in CD19 expression correlates with autoimmunity. 
  • RNA recognition by autoantigens and autoantibodies. 
  • RNA surfaces as functional mimetics of proteins. 
  • Randomised trial of plasma exchange in mild systemic lupus erythematosus. 
  • Randomization and selection of RNA to identify targets for RRM RNA-binding proteins and antibodies. 
  • Real world utilization of the myositis autoantibody panel. 
  • Recovery of B-cell homeostasis after rituximab in chronic graft-versus-host disease. 
  • Redemption of autoreactive B cells. 
  • Reduced plasmablast frequency is associated with seronegative myasthenia gravis. 
  • Regulation of Intrinsic and Bystander T Follicular Helper Cell Differentiation and Autoimmunity by Tsc1. 
  • Regulation of basement membrane-reactive B cells in BXSB, (NZBxNZW)F1, NZB, and MRL/lpr lupus mice. 
  • Regulation of the anti-Sm autoantibody response in systemic lupus erythematosus mice by monoclonal anti-Sm antibodies. 
  • Relationship of body mass index and GAD65 antibody status on β-cell secretion at diabetes onset in African-American children. 
  • Response to: "Antinuclear autoantibodies: discordance among four different assays" by Pacheco et al. 
  • Response to: 'Comment on editorial 'Pathogenic effector functions of ACPA: where do we stand'' by Holmdahl. 
  • Response to: 'Unending story of the indirect immunofluorescence assay on HEp-2 cells: old problems and new solutions?' by Meroni et al. 
  • Rethinking Autoantibody Signature Panels for Cancer Diagnosis. 
  • Rethinking the utility of acetylcholine receptor antibody titer as a pharmacodynamic biomarker for myasthenia gravis. 
  • Ribosomal P autoantibodies are present before SLE onset and are directed against non-C-terminal peptides. 
  • Rituximab as treatment for anti-MuSK myasthenia gravis: Multicenter blinded prospective review. 
  • Rituximab decreases without preference all subclasses of IgG anti-BP180 autoantibodies in refractory bullous pemphigoid (BP). 
  • Rituximab therapy for primary Sjögren's syndrome: an open-label clinical trial and mechanistic analysis. 
  • Role of ANA testing in the classification of patients with systemic lupus erythematosus. 
  • Role of the intestinal tight junction modulator zonulin in the pathogenesis of type I diabetes in BB diabetic-prone rats. 
  • Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study. 
  • Safety and efficacy of thrombin-JMI: a multidisciplinary expert group consensus. 
  • Safety, Tolerability, and Activity of ALXN1830 Targeting the Neonatal Fc Receptor in Chronic Pemphigus. 
  • Salt-split human skin substrate for the immunofluorescent screening of serum from patients with cicatricial pemphigoid and a new method of immunoprecipitation with IgA antibodies. 
  • Screening for novel central nervous system biomarkers in veterans with Gulf War Illness. 
  • Second generation automated anti-CCP test better predicts the clinical diagnosis of rheumatoid arthritis. 
  • Selective small antigenic structures are capable of inducing widespread autoimmunity which closely mimics the humoral fine specificity of human SLE. 
  • Severe adverse immunologic reaction in a patient with glioblastoma receiving autologous dendritic cell vaccines combined with GM-CSF and dose-intensified temozolomide. 
  • Side-chain specificities and molecular modelling of peptide determinants for two anti-Sm B/B' autoantibodies. 
  • Silica Exposure Differentially Modulates Autoimmunity in Lupus Strains and Autoantibody Transgenic Mice. 
  • Similar CD19 dysregulation in two autoantibody-associated autoimmune diseases suggests a shared mechanism of B-cell tolerance loss. 
  • Specificity analysis of monoclonal anti-DNA antibodies from B6-lpr/lpr mice. 
  • Specificity of antibodies to bacterial DNA in the sera of healthy human subjects and patients with systemic lupus erythematosus. 
  • Specificity of autoantibodies for recombinant 60-kd and 52-kd Ro autoantigens. 
  • Streptokinase promotes development of dipeptidyl peptidase IV (CD26) autoantibodies after fibrinolytic therapy in myocardial infarction patients. 
  • Stromal cell independent B cell development in vitro: generation and recovery of autoreactive clones. 
  • Structural availability influences the capacity of autoantigenic epitopes to induce a widespread lupus-like autoimmune response. 
  • Structural features of nephritogenic lupus autoantibodies. 
  • Structure and function of anti-DNA autoantibodies derived from a single autoimmune mouse. 
  • Superficial migratory thrombophlebitis and the lupus anticoagulant. 
  • Synthetic autoantigens of immunoglobulins and T-cell receptors: their recognition in aging, infection, and autoimmunity. 
  • Systematic protein-protein interaction and pathway analyses in the idiopathic inflammatory myopathies. 
  • Systemic lupus erythematosus and related diseases. 
  • T cells and B cells in lupus nephritis. 
  • Targeting DAMPs with nucleic acid scavengers to treat lupus. 
  • Targeting anti-beta-1-adrenergic receptor antibodies for dilated cardiomyopathy. 
  • Temporal correlation of antibody responses to different epitopes of the human La autoantigen. 
  • Th17 lymphocytes drive vascular and neuronal deficits in a mouse model of postinfectious autoimmune encephalitis. 
  • The 120-kDa soluble ectodomain of type XVII collagen is recognized by autoantibodies in patients with pemphigoid and linear IgA dermatosis. 
  • The B-cell repertoire for autoantibodies: frequency of precursor cells for anti-DNA antibodies. 
  • The Clinical Impact of Non-HLA Antibodies in Solid Organ Transplantation. 
  • The Duke Myasthenia Gravis Clinic Registry: II. Analysis of outcomes. 
  • The Duke myasthenia gravis clinic registry: I. Description and demographics. 
  • The Escherichia coli subtilase cytotoxin A subunit specifically cleaves cell-surface GRP78 protein and abolishes COOH-terminal-dependent signaling. 
  • The GS Protein-coupled A2a Adenosine Receptor Controls T Cell Help in the Germinal Center. 
  • The Interaction of Anti-DNA Antibodies with DNA: Evidence for Unconventional Binding Mechanisms. 
  • The SLE-key test serological signature: new insights into the course of lupus. 
  • The U1 RNA-binding site of the U1 small nuclear ribonucleoprotein (snRNP)-associated A protein suggests a similarity with U2 snRNPs. 
  • The binding of SLE autoantibodies to mitochondria. 
  • The clinical need for clustered AChR cell-based assay testing of seronegative MG. 
  • The clinical presentation and treatment of MOG antibody disease at a single academic center: A case series. 
  • The clinical use and immunologic impact of thrombin in surgery. 
  • The development of homologous skin-sensitizing antibodies in experimental thyroiditis. 
  • The effect of skin colour and Fitzpatrick skin type on Bullous Pemphigoid Disease Area Index (BPDAI) scores. 
  • The emerging phenotype of long-term survivors with infantile Pompe disease. 
  • The generation of extracellular DNA in SLE: the role of death and sex. 
  • The genetics of autoantibody production in MRL/lpr lupus mice. 
  • The induction of tolerance and suppression in autoimmune MRL mice using hapten-modified self. 
  • The influence of the lpr gene on B cell activation: differential antibody expression in lpr congenic mouse strains. 
  • The mechanism of autoantibody production in an autoimmune MRL/lpr mouse. 
  • The prognosis and treatment of acquired hemophilia: a systematic review and meta-analysis. 
  • The reactivity of paired plasma and serum samples are comparable in the anticardiolipin and anti-beta2-glycoprotein-1 ELISAs. 
  • The relationship of anticardiolipin antibodies to disease manifestations in pediatric systemic lupus erythematosus. 
  • The relationship of insulin secretion and GAD65 antibody levels at diagnosis on glycemic control in type 2 diabetes. 
  • The role of an autoantigen, histidyl-tRNA synthetase, in the induction and maintenance of autoimmunity. 
  • The role of antibody polyspecificity and lipid reactivity in binding of broadly neutralizing anti-HIV-1 envelope human monoclonal antibodies 2F5 and 4E10 to glycoprotein 41 membrane proximal envelope epitopes. 
  • The role of antineutrophil cytoplasmic antibody (c-ANCA) testing in the diagnosis of Wegener granulomatosis. A literature review and meta-analysis. 
  • The role of bacterial DNA in autoantibody induction. 
  • The role of cystoid macular edema as a marker in the progression of non-paraneoplastic autoimmune retinopathy. 
  • The uncertain significance of anti-glomerular basement membrane antibody among HIV-infected persons with kidney disease. 
  • Therapeutic CD154 antibody for lupus: promise for the future? 
  • Thrombosis and the antiphospholipid syndrome. 
  • Thymoma and myasthenia gravis in a 4-year-old child. Case report and review of the literature. 
  • Thyroid Autoimmune Antibodies and Major Depressive Disorder in Women. 
  • Ticlopidine- and clopidogrel-associated thrombotic thrombocytopenic purpura (TTP): review of clinical, laboratory, epidemiological, and pharmacovigilance findings (1989-2008). 
  • Topical thrombin and acquired coagulation factor inhibitors: clinical spectrum and laboratory diagnosis. 
  • Treatment of an acquired Factor XIII inhibitor in an adolescent with systemic lupus erythematosus and renal failure. 
  • Tumor necrosis factor alpha blockers and the induction of anti-DNA autoantibodies. 
  • Two patients with an anti-N-methyl-D-aspartate receptor antibody syndrome-like presentation and negative results of testing for autoantibodies. 
  • Uncommon structural motifs dominate the antigen binding site in human autoantibodies reactive with basement membrane collagen. 
  • Update on muscle-specific tyrosine kinase antibody positive myasthenia gravis. 
  • V region gene analysis of anti-Sm hybridomas from MRL/Mp-lpr/lpr mice. 
  • VH gene analysis of spontaneously activated B cells in adult MRL-lpr/lpr mice. J558 bias is not limited to classic lupus autoantibodies. 
  • Validity and cost-effectiveness of antisperm antibody testing before in vitro fertilization. 
  • Variable region sequence analysis of anti-DNA antibodies: evidence for a family of closely related germ-line VH genes encoding lupus autoantibodies. 
  • Vascular disease in the antiphospholipid syndrome: a comparison with the patient population with atherosclerosis. 
  • Vasculitis as a Major Morbidity Factor in Patients With Partial RAG Deficiency. 
  • [A severe course of bullous pemphigoid in a young man]. 
  • [Association between HSV-2 infection and serum anti-rat brain antibodies in patients with autism]. 
  • [Idiophatic inflammatory myophaties: its asociation with liver disorders]. 
  • [IgA pemphigus. Successful treatment with mycophenolate mofetil]. 
  • [Systemic manifestations of myasthenia gravis and its putative pathogenesis]. 
• 

  Keywords of People

  • Case, Laura Elizabeth, Associate Professor in Orthopaedic Surgery, Pediatrics, Medical Genetics
  • Ferrari, Guido, Professor in Surgery, Molecular Genetics and Microbiology
  • Kelsoe, Garnett H., James B. Duke Distinguished Professor of Immunology, Integrative Immunobiology
  • Shinohara, Mari L., Professor of Integrative Immunobiology, Cell Biology
  • Taylor, Gregory Alan, Professor in Medicine, Integrative Immunobiology