Bacillus subtilis
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Subject Areas on Research
- A DNA mimic: the structure and mechanism of action for the anti-repressor protein AbbA.
- Abh and AbrB control of Bacillus subtilis antimicrobial gene expression.
- Antibacterial activity of fullerene water suspensions (nC60) is not due to ROS-mediated damage.
- Antibiotic and antimalarial quinones from fungus-growing ant-associated Pseudonocardia sp.
- Appearance of a ribonucleic acid polymerase-binding protein in asporogenous mutants of Bacillus subtilis.
- Assembly dynamics of FtsZ rings in Bacillus subtilis and Escherichia coli and effects of FtsZ-regulating proteins.
- Bimodal activation of SMC ATPase by intra- and inter-molecular interactions.
- Chromosomal organization of rRNA operons in Bacillus subtilis.
- Circular ribozymes generated in Escherichia coli using group I self-splicing permuted intron-exon sequences.
- Classification and genetic characterization of pattern-forming Bacilli.
- Co-orientation of replication and transcription preserves genome integrity.
- Complexation of peptidoglycan intermediates by the lipoglycodepsipeptide antibiotic ramoplanin: minimal structural requirements for intermolecular complexation and fibril formation.
- Conformational plasticity of the coiled-coil domain of BmrR is required for bmr operator binding: the structure of unliganded BmrR.
- Crystal structure of the Bacillus subtilis anti-alpha, global transcriptional regulator, Spx, in complex with the alpha C-terminal domain of RNA polymerase.
- Crystallization and preliminary X-ray crystallographic investigations on several thermostable forms of a Bacillus subtilis lipase.
- Crystallization and preliminary X-ray diffraction studies on the DNA-binding domain of the multidrug transporter activation protein (MtaN) from Bacillus subtilis.
- Cytoskeleton. Evolution in bacteria.
- Discrete fracture patterns of virus shells reveal mechanical building blocks.
- Dynamics of backbone conformational heterogeneity in Bacillus subtilis ribonuclease P protein.
- Effect of a fullerene water suspension on bacterial phospholipids and membrane phase behavior.
- Electrostatic Energetics of Bacillus subtilis Ribonuclease P Protein Determined by Nuclear Magnetic Resonance-Based Histidine pKa Measurements.
- Endocarditis caused by Bacillus subtilis.
- Evaluation of the DNA binding tendencies of the transition state regulator AbrB.
- FtsZ filament capping by MciZ, a developmental regulator of bacterial division.
- FtsZ from divergent foreign bacteria can function for cell division in Escherichia coli.
- Generation and characterization of circular Bacillus subtilis RNase P RNA; activation by RNase P protein.
- Genetic composition of the Bacillus subtilis SOS system.
- Genetic structure and DNA sequences at junctions involved in the rearrangements of Bacillus subtilis strains carrying the trpE26 mutation.
- Insights into the nature of DNA binding of AbrB-like transcription factors.
- Instability of rRNA operons in Bacillus subtilis.
- Isolation of a new RNA polymerase-binding protein from sporulating Bacillus subtilis.
- L form bacteria growth in low-osmolality medium.
- Ligand concentration regulates the pathways of coupled protein folding and binding.
- Ligation-state hydrogen exchange: coupled binding and folding equilibria in ribonuclease P protein.
- Linked folding and anion binding of the Bacillus subtilis ribonuclease P protein.
- Long range dynamic effects of point-mutations trap a response regulator in an active conformation.
- Loss of the sigma activity of RNA polymerase of Bacillus subtilis during sporulation.
- Macromolecular assembly of the transition state regulator AbrB in its unbound and complexed states probed by microelectrospray ionization mass spectrometry.
- Mapping of rRNA genes with integrable plasmids in Bacillus subtilis.
- Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
- Molecular insights into DNA binding and anchoring by the Bacillus subtilis sporulation kinetochore-like RacA protein.
- Multiplex-PCR-based recombination as a novel high-fidelity method for directed evolution.
- NMR and XAS reveal an inner-sphere metal binding site in the P4 helix of the metallo-ribozyme ribonuclease P.
- NMR solution structure and DNA-binding model of the DNA-binding domain of competence protein A.
- NMR structure of AbhN and comparison with AbrBN: FIRST insights into the DNA binding promiscuity and specificity of AbrB-like transition state regulator proteins.
- Osmolyte-induced folding of an intrinsically disordered protein: folding mechanism in the absence of ligand.
- Oxalate decarboxylase uses electron hole hopping for catalysis.
- Phage-Resistant Bacteria Reveal a Role for Potassium in Root Colonization.
- Phosphoprotein Crh-Ser46-P displays altered binding to CcpA to effect carbon catabolite regulation.
- Predominantly buried residues in the response regulator Spo0F influence specific sensor kinase recognition.
- Preliminary structural studies on the multi-ligand-binding domain of the transcription activator, BmrR, from Bacillus subtilis.
- Probing the architecture of the B. subtilis RNase P holoenzyme active site by cross-linking and affinity cleavage.
- Probing the folding intermediate of Bacillus subtilis RNase P protein by nuclear magnetic resonance.
- Promoter recognition by a complex of Spx and the C-terminal domain of the RNA polymerase alpha subunit.
- RNA polymerase from sporulating Bacillus subtilis. Purification and properties of a modified form of the enzyme containing two sporulation polypeptides.
- Revised structure of the AbrB N-terminal domain unifies a diverse superfamily of putative DNA-binding proteins.
- Single transcriptional and translational preQ1 riboswitches adopt similar pre-folded ensembles that follow distinct folding pathways into the same ligand-bound structure.
- Solution structure and function of YndB, an AHSA1 protein from Bacillus subtilis.
- Stability studies on a lipase from Bacillus subtilis in guanidinium chloride.
- Stoichiometries of protein-protein/DNA binding and conformational changes for the transition-state regulator AbrB measured by pseudo cell-size exclusion chromatography-mass spectrometry.
- Structural basis for the metal-selective activation of the manganese transport regulator of Bacillus subtilis.
- Structural basis for the remarkable stability of Bacillus subtilis lipase (Lip A) at low pH.
- Structural basis of multidrug recognition by BmrR, a transcription activator of a multidrug transporter.
- Structural basis of selection and thermostability of laboratory evolved Bacillus subtilis lipase.
- Structural plasticity and Mg2+ binding properties of RNase P P4 from combined analysis of NMR residual dipolar couplings and motionally decoupled spin relaxation.
- Structure and DNA-binding traits of the transition state regulator AbrB.
- Structure and functional properties of the Bacillus subtilis transcriptional repressor Rex.
- Structure of an OhrR-ohrA operator complex reveals the DNA binding mechanism of the MarR family.
- Structure of the endonuclease domain of MutL: unlicensed to cut.
- Structure of the manganese-bound manganese transport regulator of Bacillus subtilis.
- Structures of BmrR-drug complexes reveal a rigid multidrug binding pocket and transcription activation through tyrosine expulsion.
- Structures of carbon catabolite protein A-(HPr-Ser46-P) bound to diverse catabolite response element sites reveal the basis for high-affinity binding to degenerate DNA operators.
- Structures of partition protein ParA with nonspecific DNA and ParB effector reveal molecular insights into principles governing Walker-box DNA segregation.
- Structures of regulatory machinery reveal novel molecular mechanisms controlling B. subtilis nitrogen homeostasis.
- Structures of the Bacillus subtilis glutamine synthetase dodecamer reveal large intersubunit catalytic conformational changes linked to a unique feedback inhibition mechanism.
- Sustained release of antibiotics from injectable and thermally responsive polypeptide depots.
- Tandem mass spectrometry acquisition approaches to enhance identification of protein-protein interactions using low-energy collision-induced dissociative chemical crosslinking reagents.
- The NMR solution structure of BeF(3)(-)-activated Spo0F reveals the conformational switch in a phosphorelay system.
- The Solution Structures and Interaction of SinR and SinI: Elucidating the Mechanism of Action of the Master Regulator Switch for Biofilm Formation in Bacillus subtilis.
- The conformations of the manganese transport regulator of Bacillus subtilis in its metal-free state.
- The lipid lysyl-phosphatidylglycerol is present in membranes of Rhizobium tropici CIAT899 and confers increased resistance to polymyxin B under acidic growth conditions.
- The nucleotide messenger (p)ppGpp is an anti-inducer of the purine synthesis transcription regulator PurR in Bacillus.
- The structure of the trpE, trpD and 5' trpC genes of Bacillus pumilus.
- Thermodynamic characterization of the osmolyte- and ligand-folded states of Bacillus subtilis ribonuclease P protein.
- Trait-to-gene: a computational method for predicting the function of uncharacterized genes.
- Two tRNA gene clusters associated with rRNA operons rrnD and rrnE in Bacillus subtilis.
- Use of poly-l-aspartic acid to inhibit aminoglycoside cochlear ototoxicity.
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Keywords of People
- Erickson, Harold Paul, James B. Duke Distinguished Professor Emeritus, Cell Biology