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Subject Areas on Research
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A DNA mimic: the structure and mechanism of action for the anti-repressor protein AbbA.
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Antibacterial activity of fullerene water suspensions (nC60) is not due to ROS-mediated damage.
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Antibiotic and antimalarial quinones from fungus-growing ant-associated Pseudonocardia sp.
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Appearance of a ribonucleic acid polymerase-binding protein in asporogenous mutants of Bacillus subtilis.
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Assembly dynamics of FtsZ rings in Bacillus subtilis and Escherichia coli and effects of FtsZ-regulating proteins.
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Bimodal activation of SMC ATPase by intra- and inter-molecular interactions.
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Cell-directed assembly of lipid-silica nanostructures providing extended cell viability.
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Chromosomal organization of rRNA operons in Bacillus subtilis.
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Circular ribozymes generated in Escherichia coli using group I self-splicing permuted intron-exon sequences.
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Classification and genetic characterization of pattern-forming Bacilli.
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Co-orientation of replication and transcription preserves genome integrity.
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Complexation of peptidoglycan intermediates by the lipoglycodepsipeptide antibiotic ramoplanin: minimal structural requirements for intermolecular complexation and fibril formation.
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Conformational plasticity of the coiled-coil domain of BmrR is required for bmr operator binding: the structure of unliganded BmrR.
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Crystal structure of the Bacillus subtilis anti-alpha, global transcriptional regulator, Spx, in complex with the alpha C-terminal domain of RNA polymerase.
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Crystallization and preliminary X-ray crystallographic investigations on several thermostable forms of a Bacillus subtilis lipase.
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Crystallization and preliminary X-ray diffraction studies on the DNA-binding domain of the multidrug transporter activation protein (MtaN) from Bacillus subtilis.
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Cytoskeleton. Evolution in bacteria.
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Dimer recognition and secretion by the ESX secretion system in Bacillus subtilis.
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Directed evolution of subtilisin E in Bacillus subtilis to enhance total activity in aqueous dimethylformamide.
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Dynamics of backbone conformational heterogeneity in Bacillus subtilis ribonuclease P protein.
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Effect of a fullerene water suspension on bacterial phospholipids and membrane phase behavior.
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Electrostatic Energetics of Bacillus subtilis Ribonuclease P Protein Determined by Nuclear Magnetic Resonance-Based Histidine pKa Measurements.
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Endocarditis caused by Bacillus subtilis.
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Environmental Persistence of Bacillus anthracis and Bacillus subtilis Spores.
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Enzyme derivatives containing reactive groups. II. Immobilization of alpha-amylase on human erythrocytes using 5,5 dithiobis (2 nitro benzoic acid) and M-maleimidobenzoic acid adducts.
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Enzyme derivatives containing reactive groups. Immobilization of alpha-amylase on human erythrocytes.
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FtsZ filament capping by MciZ, a developmental regulator of bacterial division.
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FtsZ from divergent foreign bacteria can function for cell division in Escherichia coli.
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Generation and characterization of circular Bacillus subtilis RNase P RNA; activation by RNase P protein.
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Genetic composition of the Bacillus subtilis SOS system.
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Genetic structure and DNA sequences at junctions involved in the rearrangements of Bacillus subtilis strains carrying the trpE26 mutation.
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Instability of rRNA operons in Bacillus subtilis.
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Isolation of a new RNA polymerase-binding protein from sporulating Bacillus subtilis.
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Ligand concentration regulates the pathways of coupled protein folding and binding.
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Ligation-state hydrogen exchange: coupled binding and folding equilibria in ribonuclease P protein.
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Linked domain architectures allow for specialization of function in the FtsK/SpoIIIE ATPases of ESX secretion systems.
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Linked folding and anion binding of the Bacillus subtilis ribonuclease P protein.
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Loss of the sigma activity of RNA polymerase of Bacillus subtilis during sporulation.
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Mapping of rRNA genes with integrable plasmids in Bacillus subtilis.
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Molecular insights into DNA binding and anchoring by the Bacillus subtilis sporulation kinetochore-like RacA protein.
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Multiplex-PCR-based recombination as a novel high-fidelity method for directed evolution.
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NMR and XAS reveal an inner-sphere metal binding site in the P4 helix of the metallo-ribozyme ribonuclease P.
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Novel mutations that alter the regulation of sporulation in Bacillus subtilis. Evidence that phosphorylation of regulatory protein SpoOA controls the initiation of sporulation.
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Osmolyte-induced folding of an intrinsically disordered protein: folding mechanism in the absence of ligand.
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Phosphoprotein Crh-Ser46-P displays altered binding to CcpA to effect carbon catabolite regulation.
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Preliminary structural studies on the multi-ligand-binding domain of the transcription activator, BmrR, from Bacillus subtilis.
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Probing the folding intermediate of Bacillus subtilis RNase P protein by nuclear magnetic resonance.
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Promoter recognition by a complex of Spx and the C-terminal domain of the RNA polymerase alpha subunit.
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Purification and characterization of a fibrinolytic enzyme of Bacillus subtilis DC33, isolated from Chinese traditional Douchi.
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RNA polymerase from sporulating Bacillus subtilis. Purification and properties of a modified form of the enzyme containing two sporulation polypeptides.
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Single transcriptional and translational preQ1 riboswitches adopt similar pre-folded ensembles that follow distinct folding pathways into the same ligand-bound structure.
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Solution structure and function of YndB, an AHSA1 protein from Bacillus subtilis.
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Stability studies on a lipase from Bacillus subtilis in guanidinium chloride.
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Structural basis for the metal-selective activation of the manganese transport regulator of Bacillus subtilis.
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Structural basis for the remarkable stability of Bacillus subtilis lipase (Lip A) at low pH.
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Structural basis of multidrug recognition by BmrR, a transcription activator of a multidrug transporter.
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Structural basis of selection and thermostability of laboratory evolved Bacillus subtilis lipase.
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Structural characterization of the late competence protein ComFB from Bacillus subtilis.
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Structural plasticity and Mg2+ binding properties of RNase P P4 from combined analysis of NMR residual dipolar couplings and motionally decoupled spin relaxation.
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Structure and DNA-binding traits of the transition state regulator AbrB.
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Structure and functional properties of the Bacillus subtilis transcriptional repressor Rex.
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Structure of an OhrR-ohrA operator complex reveals the DNA binding mechanism of the MarR family.
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Structure of the Drosophila DNA topoisomerase II gene. Nucleotide sequence and homology among topoisomerases II.
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Structure of the endonuclease domain of MutL: unlicensed to cut.
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Structure of the manganese-bound manganese transport regulator of Bacillus subtilis.
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Structures of BmrR-drug complexes reveal a rigid multidrug binding pocket and transcription activation through tyrosine expulsion.
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Structures of carbon catabolite protein A-(HPr-Ser46-P) bound to diverse catabolite response element sites reveal the basis for high-affinity binding to degenerate DNA operators.
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Structures of partition protein ParA with nonspecific DNA and ParB effector reveal molecular insights into principles governing Walker-box DNA segregation.
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Structures of regulatory machinery reveal novel molecular mechanisms controlling B. subtilis nitrogen homeostasis.
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Structures of the Bacillus subtilis glutamine synthetase dodecamer reveal large intersubunit catalytic conformational changes linked to a unique feedback inhibition mechanism.
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Sustained release of antibiotics from injectable and thermally responsive polypeptide depots.
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Tandem mass spectrometry acquisition approaches to enhance identification of protein-protein interactions using low-energy collision-induced dissociative chemical crosslinking reagents.
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The NMR solution structure of BeF(3)(-)-activated Spo0F reveals the conformational switch in a phosphorelay system.
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The conformations of the manganese transport regulator of Bacillus subtilis in its metal-free state.
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The lipid lysyl-phosphatidylglycerol is present in membranes of Rhizobium tropici CIAT899 and confers increased resistance to polymyxin B under acidic growth conditions.
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The structure of the trpE, trpD and 5' trpC genes of Bacillus pumilus.
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Thermodynamic characterization of the osmolyte- and ligand-folded states of Bacillus subtilis ribonuclease P protein.
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Trait-to-gene: a computational method for predicting the function of uncharacterized genes.
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Two tRNA gene clusters associated with rRNA operons rrnD and rrnE in Bacillus subtilis.
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Use of poly-l-aspartic acid to inhibit aminoglycoside cochlear ototoxicity.
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