Bacterial Proteins

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  Subject Areas on Research

  • 5'-Terminal nucleotide sequence of Escherichia coli lactose repressor mRNA: features of translational initiation and reinitiation sites. 
  • 50 million years of genomic stasis in endosymbiotic bacteria. 
  • A 13-kilodalton maize mitochondrial protein in E. coli confers sensitivity to Bipolaris maydis toxin. 
  • A Bayesian approach for determining protein side-chain rotamer conformations using unassigned NOE data. 
  • A Bgl II polymorphism detected by LDR152 [D19S19]. 
  • A CRISPR-Cas system enhances envelope integrity mediating antibiotic resistance and inflammasome evasion. 
  • A DNA mimic: the structure and mechanism of action for the anti-repressor protein AbbA. 
  • A common clathrin-mediated machinery co-ordinates cell-cell adhesion and bacterial internalization. 
  • A comparison of the constituent polypeptides of the B-800--850 light-harvesting pigment-protein complex from Rhodopseudomonas sphaeroides. 
  • A geometric arrangement algorithm for structure determination of symmetric protein homo-oligomers from NOEs and RDCs. 
  • A graphical method for analyzing distance restraints using residual dipolar couplings for structure determination of symmetric protein homo-oligomers. 
  • A new H/D exchange- and mass spectrometry-based method for thermodynamic analysis of protein-DNA interactions. 
  • A noncanonical function of sortase enables site-specific conjugation of small molecules to lysine residues in proteins. 
  • A novel relaxase homologue is involved in chromosomal DNA processing for type IV secretion in Neisseria gonorrhoeae. 
  • A pH-gated conformational switch regulates the phosphatase activity of bifunctional HisKA-family histidine kinases. 
  • A power-law dependence of bacterial invasion on mammalian host receptors. 
  • A pseudoknot in the 3' non-core region of the glmS ribozyme enhances self-cleavage activity. 
  • A quantitative, high-throughput screen for protein stability. 
  • A rapid fluorescence assay for FtsZ assembly indicates cooperative assembly with a dimer nucleus. 
  • A solubility-enhancement tag (SET) for NMR studies of poorly behaving proteins. 
  • A strong effect of AT mutational bias on amino acid usage in Buchnera is mitigated at high-expression genes. 
  • A structural pathway for signaling in the E46Q mutant of photoactive yellow protein. 
  • A thioesterase bypasses the requirement for exogenous fatty acids in the plsX deletion of Streptococcus pneumoniae. 
  • Abundance and genetic diversity of aerobic anoxygenic phototrophic bacteria of coastal regions of the pacific ocean. 
  • Actin and intermediate filaments stabilize the Chlamydia trachomatis vacuole by forming dynamic structural scaffolds. 
  • Activation of MAPK/ERK signaling by Burkholderia pseudomallei cycle inhibiting factor (Cif). 
  • Adenylate cyclase toxin (ACT) from Bordetella hinzii: characterization and differences from ACT of Bordetella pertussis. 
  • Allergic reactions to E. coli L-asparaginase do not affect outcome in childhood B-precursor acute lymphoblastic leukemia: a Children's Oncology Group Study. 
  • Amino acid permeases require COPII components and the ER resident membrane protein Shr3p for packaging into transport vesicles in vitro. 
  • Amphiphilic α-helical potential: a putative folding motif adding few constraints to protein evolution. 
  • Amplification of antigen-antibody interactions based on biotin labeled protein-streptavidin network complex using impedance spectroscopy. 
  • An Escherichia coli mutant defective in lipid export. 
  • An essential transcription factor, SciP, enhances robustness of Caulobacter cell cycle regulation. 
  • An inner membrane dioxygenase that generates the 2-hydroxymyristate moiety of Salmonella lipid A. 
  • An undecaprenyl phosphate-aminoarabinose flippase required for polymyxin resistance in Escherichia coli. 
  • Analysis of experimental time-resolved crystallographic data by singular value decomposition. 
  • Analysis of phenylthiohydantoin amino acid mixtures for sequencing by thermospray liquid chromatography/mass spectrometry. 
  • Annihilating host defense. 
  • Antagonism of toxigenic Clostridium difficile by nontoxigenic C. difficile. 
  • Apparent cooperative assembly of the bacterial cell division protein FtsZ demonstrated by isothermal titration calorimetry. 
  • Appearance of a ribonucleic acid polymerase-binding protein in asporogenous mutants of Bacillus subtilis. 
  • Application of singular value decomposition to the analysis of time-resolved macromolecular x-ray data. 
  • Aptamers: an emerging class of therapeutics. 
  • Arc/Arg3.1 translation is controlled by convergent N-methyl-D-aspartate and Gs-coupled receptor signaling pathways. 
  • Assembly and molecular activities of the MutS tetramer. 
  • Assembly dynamics of FtsZ rings in Bacillus subtilis and Escherichia coli and effects of FtsZ-regulating proteins. 
  • Assembly dynamics of Mycobacterium tuberculosis FtsZ. 
  • Assembly of a chemically synthesized peptide of Escherichia coli type 1 fimbriae into fimbria-like antigenic structures. 
  • Assembly of the bacteriophage T4 primosome: single-molecule and ensemble studies. 
  • Assessment of a quantitative multiplex 5' nuclease real-time PCR for spotted fever and typhus group rickettsioses and Orientia tsutsugamushi. 
  • Assessment of the CFTR and ENaC association. 
  • Assignment of the 1H, 13C and 15N resonances of the LpxC deacetylase from Aquifex aeolicus in complex with the substrate-analog inhibitor TU-514. 
  • Association of Helicobacter pylori infection and diet on the risk of gastric cancer: a case-control study in Hawaii. 
  • Atomic structures of tubulin and FtsZ. 
  • Bacterial CRISPR/Cas DNA endonucleases: A revolutionary technology that could dramatically impact viral research and treatment. 
  • Bacterial cell division protein FtsZ assembles into protofilament sheets and minirings, structural homologs of tubulin polymers. 
  • Bacterial genetics by flow cytometry: rapid isolation of Salmonella typhimurium acid-inducible promoters by differential fluorescence induction. 
  • Bacterial infection remains a leading cause of death in both Western and developing world. Preface. 
  • Bacterial-host-cell tethers. 
  • Bacteriophage T4 UvsW protein is a helicase involved in recombination, repair and the regulation of DNA replication origins. 
  • Bimodal activation of SMC ATPase by intra- and inter-molecular interactions. 
  • Binding of MetJ repressor to specific and nonspecific DNA and effect of S-adenosylmethionine on these interactions. 
  • Biochemical and structural insights into bacterial organelle form and biogenesis. 
  • Biochemical role of the Cryptococcus neoformans ADE2 protein in fungal de novo purine biosynthesis. 
  • Biochemistry. Photosynthesis from the protein's perspective. 
  • Biological functions and biogenesis of secreted bacterial outer membrane vesicles. 
  • Biosynthesis of undecaprenyl phosphate-galactosamine and undecaprenyl phosphate-glucose in Francisella novicida. 
  • Blastomyces dermatitidis chemotactic factor: kinetics of production and biological characterization evaluated by a modified neutrophil chemotaxis assay. 
  • Bonds between fibronectin and fibronectin-binding proteins on Staphylococcus aureus and Lactococcus lactis. 
  • Borate as a synergistic anion for Marinobacter algicola ferric binding protein, FbpA: a role for boron in iron transport in marine life. 
  • Bordetella pertussis FbpA binds both unchelated iron and iron siderophore complexes. 
  • BtubA-BtubB heterodimer is an essential intermediate in protofilament assembly. 
  • C-terminally truncated derivatives of Escherichia coli Hfq are proficient in riboregulation. 
  • CNS1 encodes an essential p60/Sti1 homolog in Saccharomyces cerevisiae that suppresses cyclophilin 40 mutations and interacts with Hsp90. 
  • Caenorhabditis elegans as a host for the study of host-pathogen interactions. 
  • Caenorhabditis elegans innate immune response triggered by Salmonella enterica requires intact LPS and is mediated by a MAPK signaling pathway. 
  • Caenorhabditis elegans-based screen identifies Salmonella virulence factors required for conserved host-pathogen interactions. 
  • Cas9 loosens its grip on off-target sites. 
  • Cell division without FtsZ--a variety of redundant mechanisms. 
  • Cellular cytoskeleton dynamics modulates non-viral gene delivery through RhoGTPases. 
  • Chaperone-assisted assembly and molecular architecture of adhesive pili. 
  • Chapter 1 - Tubular liposomes with variable permeability for reconstitution of FtsZ rings. 
  • Characterisation of PduS, the pdu metabolosome corrin reductase, and evidence of substructural organisation within the bacterial microcompartment. 
  • Characterization of Escherichia coli MoeB and its involvement in the activation of molybdopterin synthase for the biosynthesis of the molybdenum cofactor. 
  • Characterization of Mycobacterium montefiorense sp. nov., a novel pathogenic Mycobacterium from moray eels that is related to Mycobacterium triplex. 
  • Characterization of Staphylococcus aureus Cas9: a smaller Cas9 for all-in-one adeno-associated virus delivery and paired nickase applications. 
  • Characterization of a putative periplasmic transport system for octopine accumulation encoded by Agrobacterium tumefaciens Ti plasmid pTiA6. 
  • Characterization of an iron-sulfur cluster assembly protein (ISU1) from Schizosaccharomyces pombe. 
  • Characterization of the SarA virulence gene regulator of Staphylococcus aureus. 
  • Characterization of the multiple transferable resistance repressor, MtrR, from Neisseria gonorrhoeae. 
  • Chemisorptions of bacterial receptors for hydrophobic amino acids and sugars on gold for biosensor applications: a surface plasmon resonance study of genetically engineered proteins. 
  • Chlamydia effector proteins and new insights into chlamydial cellular microbiology. 
  • Chromophore conformation and the evolution of tertiary structural changes in photoactive yellow protein. 
  • Clathrin phosphorylation is required for actin recruitment at sites of bacterial adhesion and internalization. 
  • Clinical microbiology costs for methods of active surveillance for Klebsiella pneumoniae carbapenemase-producing Enterobacteriaceae. 
  • Cloning and analysis of a Candida albicans gene that affects cell surface hydrophobicity. 
  • Clostridial toxins: sensing a target in a hostile gut environment. 
  • Clostridium taeniosporum spore ribbon-like appendage structure, composition and genes. 
  • Comparison of acellular pertussis-diphtheria-tetanus toxoids and Haemophilus influenzae type b vaccines administered separately vs. combined in younger vs. older toddlers. 
  • Comparison of seven techniques for typing international epidemic strains of Clostridium difficile: restriction endonuclease analysis, pulsed-field gel electrophoresis, PCR-ribotyping, multilocus sequence typing, multilocus variable-number tandem-repeat analysis, amplified fragment length polymorphism, and surface layer protein A gene sequence typing. 
  • Comparison of the safety and immunogenicity of an investigational and a licensed quadrivalent meningococcal conjugate vaccine in children 2-10 years of age. 
  • Comparison of two rapid assays for Clostridium difficile Common antigen and a C difficile toxin A/B assay with the cell culture neutralization assay. 
  • Conformational changes of FtsZ reported by tryptophan mutants. 
  • Conformational kinetics reveals affinities of protein conformational states. 
  • Conformational plasticity of the coiled-coil domain of BmrR is required for bmr operator binding: the structure of unliganded BmrR. 
  • Conservation of the D-mannose-adhesion protein among type 1 fimbriated members of the family Enterobacteriaceae. 
  • Conservation of the chitin utilization pathway in the Vibrionaceae. 
  • Constitutive expression of a groEL-related protein on the surface of human gamma/delta cells. 
  • Control of protein-ligand recognition using a stimuli-responsive polymer. 
  • Controlling mRNA stability and translation with the CRISPR endoribonuclease Csy4. 
  • Conversion of a maltose receptor into a zinc biosensor by computational design. 
  • Correlation of cefoxitin MICs with the presence of mecA in Staphylococcus spp. 
  • Coxiella burnetii effector proteins that localize to the parasitophorous vacuole membrane promote intracellular replication. 
  • Crosstalk between bacterial chemotaxis signal transduction proteins and regulators of transcription of the Ntr regulon: evidence that nitrogen assimilation and chemotaxis are controlled by a common phosphotransfer mechanism. 
  • Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex. 
  • Cryo-EM Structures of the Magnesium Channel CorA Reveal Symmetry Break upon Gating. 
  • Crystal structure of MraY, an essential membrane enzyme for bacterial cell wall synthesis. 
  • Crystal structure of Streptococcus pyogenes sortase A: implications for sortase mechanism. 
  • Crystal structure of a photoactive yellow protein from a sensor histidine kinase: conformational variability and signal transduction. 
  • Crystal structure of activated CheY. Comparison with other activated receiver domains. 
  • Crystal structure of an activated response regulator bound to its target. 
  • Crystal structure of an efficacious gonococcal adherence inhibitor: an enolase from Lactobacillus gasseri. 
  • Crystal structure of the Bacillus subtilis anti-alpha, global transcriptional regulator, Spx, in complex with the alpha C-terminal domain of RNA polymerase. 
  • Crystal structure of the MOP flippase MurJ in an inward-facing conformation. 
  • Crystal structure of the gephyrin-related molybdenum cofactor biosynthesis protein MogA from Escherichia coli. 
  • Crystal structure of the lactose operon repressor and its complexes with DNA and inducer. 
  • Crystal structure of the transcription activator BmrR bound to DNA and a drug. 
  • Crystal structures of SarA, a pleiotropic regulator of virulence genes in S. aureus. 
  • Crystallization and preliminary X-ray crystallographic investigations on several thermostable forms of a Bacillus subtilis lipase. 
  • Crystallization and preliminary X-ray diffraction studies on the DNA-binding domain of the multidrug transporter activation protein (MtaN) from Bacillus subtilis. 
  • Crystallization, preliminary X-ray analysis and biophysical characterization of HPr kinase/phosphatase of Mycoplasma pneumoniae. 
  • Curative Treatment of Severe Gram-Negative Bacterial Infections by a New Class of Antibiotics Targeting LpxC. 
  • Curved FtsZ protofilaments generate bending forces on liposome membranes. 
  • Cytoplasmic lipid droplets are translocated into the lumen of the Chlamydia trachomatis parasitophorous vacuole. 
  • Cytoskeletal reorganization by G protein-coupled receptors is dependent on phosphoinositide 3-kinase gamma, a Rac guanosine exchange factor, and Rac. 
  • Cytoskeleton. Evolution in bacteria. 
  • DNA damage responses in prokaryotes: regulating gene expression, modulating growth patterns, and manipulating replication forks. 
  • DNA mismatch repair: functions and mechanisms. 
  • Daptomycin-resistant Enterococcus faecalis diverts the antibiotic molecule from the division septum and remodels cell membrane phospholipids. 
  • Derivatives of plant phenolic compound affect the type III secretion system of Pseudomonas aeruginosa via a GacS-GacA two-component signal transduction system. 
  • Detection of Cytosolic Shigella flexneri via a C-Terminal Triple-Arginine Motif of GBP1 Inhibits Actin-Based Motility. 
  • Development of a high-performance liquid chromatography assay and revision of kinetic parameters for the Staphylococcus aureus sortase transpeptidase SrtA. 
  • Development of a novel quadruple auxotrophic host transformation system by argB gene disruption using adeA gene and exploiting adenine auxotrophy in Aspergillus oryzae. 
  • Differential Translocation of Host Cellular Materials into the Chlamydia trachomatis Inclusion Lumen during Chemical Fixation. 
  • Differential actions of PAR2 and PAR1 in stimulating human endothelial cell exocytosis and permeability: the role of Rho-GTPases. 
  • Differential and simultaneous adenosine di- and triphosphate binding by MutS. 
  • Difluoromethylornithine is a novel inhibitor of Helicobacter pylori growth, CagA translocation, and interleukin-8 induction. 
  • Dihydrophenylalanine: a prephenate-derived Photorhabdus luminescens antibiotic and intermediate in dihydrostilbene biosynthesis. 
  • Dimer recognition and secretion by the ESX secretion system in Bacillus subtilis. 
  • Dimerization is required for the activity of the protein histidine kinase CheA that mediates signal transduction in bacterial chemotaxis. 
  • Direct analysis of backbone-backbone hydrogen bond formation in protein folding transition states. 
  • Disruption of Arp2/3 results in asymmetric structural plasticity of dendritic spines and progressive synaptic and behavioral abnormalities. 
  • Dissemination of an Enterococcus Inc18-Like vanA plasmid associated with vancomycin-resistant Staphylococcus aureus. 
  • Division of labour between Myc and G1 cyclins in cell cycle commitment and pace control. 
  • Domain unfolding plays a role in superfibronectin formation. 
  • Dynamics of HIV neutralization by a microbicide formulation layer: biophysical fundamentals and transport theory. 
  • Dynamin and FtsZ. Missing links in mitochondrial and bacterial division. 
  • Effective induction of protective systemic immunity with nasally administered vaccines adjuvanted with IL-1. 
  • Efficacy and safety of live attenuated persistent and rapidly cleared Mycobacterium tuberculosis vaccine candidates in non-human primates. 
  • Elicitation of epithelial cell-derived immune effectors by outer membrane vesicles of nontypeable Haemophilus influenzae. 
  • Elucidation of a [4Fe-4S] cluster degradation pathway: rapid kinetic studies of the degradation of Chromatium vinosum HiPIP. 
  • Endotoxin (LPS) stimulates in vitro migration of macrophages from LPS-resistant mice but not from LPS-sensitive mice. 
  • Engineering key components in a synthetic eukaryotic signal transduction pathway. 
  • Engineering prokaryotic channels for control of mammalian tissue excitability. 
  • Engineering the substrate specificity of Staphylococcus aureus Sortase A. The beta6/beta7 loop from SrtB confers NPQTN recognition to SrtA. 
  • Enhanced priming of adaptive immunity by Mycobacterium smegmatis mutants with high-level protein secretion. 
  • Enhanced priming of adaptive immunity by a proapoptotic mutant of Mycobacterium tuberculosis. 
  • Enhancer-origin interaction in plasmid R6K involves a DNA loop mediated by initiator protein. 
  • Enzymatic properties of ALDH1L2, a mitochondrial 10-formyltetrahydrofolate dehydrogenase. 
  • Escherichia coli MoeA and MogA. Function in metal incorporation step of molybdenum cofactor biosynthesis. 
  • Escherichia coli biotin holoenzyme synthetase/bio repressor crystal structure delineates the biotin- and DNA-binding domains. 
  • Escherichia coli mutS-encoded protein binds to mismatched DNA base pairs. 
  • Evaluation of pertussis in U.S. Marine Corps trainees. 
  • Evaluation of the accuracy and reproducibility of a practical PCR panel assay for rapid detection and differentiation of Mycobacterium avium subspecies. 
  • Evidence for genetic drift in endosymbionts (Buchnera): analyses of protein-coding genes. 
  • Evolution of the cytoskeleton. 
  • Examination of type IV pilus expression and pilus-associated phenotypes in Kingella kingae clinical isolates. 
  • Examining relationships between total silver concentration and Sil silver resistance genes in domestic wastewater treatment plants. 
  • Exploitation of macrophages as a replication niche by Legionella pneumophila: response. 
  • Exploring biological electron transfer pathway dynamics with the Pathways plugin for VMD. 
  • Expression of Kingella kingae type IV pili is regulated by sigma54, PilS, and PilR. 
  • Expression of penicillin G acylase from the cloned pac gene of Escherichia coli ATCC11105. Effects of pacR and temperature. 
  • Expression of photosynthesis genes in relation to nitrogen fixation in the diazotrophic filamentous nonheterocystous cyanobacterium Trichodesmium sp. IMS 101. 
  • Expression of the Salmonella spp. virulence factor SifA in yeast alters Rho1 activity on peroxisomes. 
  • Extraintestinal dissemination of Salmonella by CD18-expressing phagocytes. 
  • FabH mutations confer resistance to FabF-directed antibiotics in Staphylococcus aureus. 
  • FbpA--a bacterial transferrin with more to offer. 
  • Fe3+ coordination and redox properties of a bacterial transferrin. 
  • Fecal leukocytes in stool specimens submitted for Clostridium difficile toxin assay. 
  • FimC is a periplasmic PapD-like chaperone that directs assembly of type 1 pili in bacteria. 
  • FimH adhesin of type 1 pili is assembled into a fibrillar tip structure in the Enterobacteriaceae. 
  • Flavohemoglobin denitrosylase catalyzes the reaction of a nitroxyl equivalent with molecular oxygen. 
  • Fluorescence resonance energy transfer analysis of cell surface receptor interactions and signaling using spectral variants of the green fluorescent protein. 
  • Fluorescence-based isolation of bacterial genes expressed within host cells. 
  • FtsZ Protofilament Curvature Is the Opposite of Tubulin Rings. 
  • FtsZ condensates: an in vitro electron microscopy study. 
  • FtsZ filament capping by MciZ, a developmental regulator of bacterial division. 
  • FtsZ filament dynamics at steady state: subunit exchange with and without nucleotide hydrolysis. 
  • FtsZ from Escherichia coli, Azotobacter vinelandii, and Thermotoga maritima--quantitation, GTP hydrolysis, and assembly. 
  • FtsZ from divergent foreign bacteria can function for cell division in Escherichia coli. 
  • FtsZ in bacterial cytokinesis: cytoskeleton and force generator all in one. 
  • FtsZ, a prokaryotic homolog of tubulin? 
  • Functional consequences of substitution mutations in MepR, a repressor of the Staphylococcus aureus MepA multidrug efflux pump gene. 
  • Galectin-3 directs antimicrobial guanylate binding proteins to vacuoles furnished with bacterial secretion systems. 
  • Gene expression levels influence amino acid usage and evolutionary rates in endosymbiotic bacteria. 
  • Genetic composition of the Bacillus subtilis SOS system. 
  • Genetic diversity among Mycobacterium avium complex strains recovered from children with and without human immunodeficiency virus infection. 
  • Genotypic characteristics of Staphylococcus aureus isolates from a multinational trial of complicated skin and skin structure infections. 
  • Global Mapping of the Inc-Human Interactome Reveals that Retromer Restricts Chlamydia Infection. 
  • Glutamate decreases mitochondrial size and movement in primary forebrain neurons. 
  • Glutathione S-transferase fusion proteins mimic receptor dimerization in permeabilized cells. 
  • Glutathione activates virulence gene expression of an intracellular pathogen. 
  • HIV-1 neutralization profile and plant-based recombinant expression of actinohivin, an Env glycan-specific lectin devoid of T-cell mitogenic activity. 
  • Helicobacter pylori detection and genotyping in gastric biopsy specimens from Chennai patients (India). 
  • Helicobacter pylori induces apoptosis of human monocytes but not monocyte-derived dendritic cells: role of the cag pathogenicity island. 
  • High susceptibility of MDR and XDR Gram-negative pathogens to biphenyl-diacetylene-based difluoromethyl-allo-threonyl-hydroxamate LpxC inhibitors. 
  • High-frequency S-layer protein variation in Campylobacter fetus revealed by sapA mutagenesis. 
  • How an enzyme binds the C1 carrier tetrahydromethanopterin. Structure of the tetrahydromethanopterin-dependent formaldehyde-activating enzyme (Fae) from Methylobacterium extorquens AM1. 
  • How bacterial cell division might cheat turgor pressure - a unified mechanism of septal division in Gram-positive and Gram-negative bacteria. 
  • Hydrolytically deficient MutS E694A is defective in the MutL-dependent activation of MutH and in the mismatch-dependent assembly of the MutS.MutL.heteroduplex complex. 
  • Identification of Icm protein complexes that play distinct roles in the biogenesis of an organelle permissive for Legionella pneumophila intracellular growth. 
  • Identification of a chloroform-soluble membrane miniprotein in Escherichia coli and its homolog in Salmonella typhimurium. 
  • Identification of a homogentisate-1,2-dioxygenase gene in the fungus Exophiala lecanii-corni: analysis and implications. 
  • Identification of a regulated alkaline phosphatase, a cell surface-associated lipoprotein, in Mycobacterium smegmatis. 
  • Identification of a two-component fatty acid kinase responsible for host fatty acid incorporation by Staphylococcus aureus. 
  • Identification of an inhibitory circuit that regulates cerebellar Golgi cell activity. 
  • Identification of the carotenoid present in the B-800-850 antenna complex from Rhodopseudomonas capsulata as that which responds electrochromically to transmembrane electric fields. 
  • Identification of the second chromophore of Escherichia coli and yeast DNA photolyases as 5,10-methenyltetrahydrofolate. 
  • Identification of two ancillary subunits of Escherichia coli type 1 fimbriae by using antibodies against synthetic oligopeptides of fim gene products. 
  • Identification of undecaprenyl phosphate-beta-D-galactosamine in Francisella novicida and its function in lipid A modification. 
  • Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer. 
  • Immunization with Salmonella enterica serovar Typhimurium-derived outer membrane vesicles delivering the pneumococcal protein PspA confers protection against challenge with Streptococcus pneumoniae. 
  • Immunization with the Haemophilus ducreyi hemoglobin receptor HgbA with adjuvant monophosphoryl lipid A protects swine from a homologous but not a heterologous challenge. 
  • Improved excitation pulse bandwidths using shaped pulses, with application to heteronuclear half filters in macromolecular NMR. 
  • In vitro assembly and GTP hydrolysis by bacterial tubulins BtubA and BtubB. 
  • In vitro assembly studies of FtsZ/tubulin-like proteins (TubZ) from Bacillus plasmids: evidence for a capping mechanism. 
  • In vitro synthesis of molybdopterin from precursor Z using purified converting factor. Role of protein-bound sulfur in formation of the dithiolene. 
  • In vivo characterization of Escherichia coli ftsZ mutants: effects on Z-ring structure and function. 
  • In vivo post-translational processing and subunit reconstitution of cephalosporin acylase from Pseudomonas sp. 130. 
  • Incorporation of extracellular fatty acids by a fatty acid kinase-dependent pathway in Staphylococcus aureus. 
  • Indole-3-acetic acid biosynthesis is deficient in Gluconacetobacter diazotrophicus strains with mutations in cytochrome c biogenesis genes. 
  • Inducing circular RNA formation using the CRISPR endoribonuclease Csy4. 
  • Induction of mitogenic signalling in the 1LN prostate cell line on exposure to submicromolar concentrations of cadmium+. 
  • Influence of berberine sulfate on synthesis and expression of Pap fimbrial adhesin in uropathogenic Escherichia coli. 
  • Informing Antibiotic Treatment Decisions: Evaluating Rapid Molecular Diagnostics To Identify Susceptibility and Resistance to Carbapenems against Acinetobacter spp. in PRIMERS III. 
  • Inhibition of Methicillin-resistant Staphylococcus aureus-induced cytokines mRNA production in human bone marrow derived mesenchymal stem cells by 1,25-dihydroxyvitamin D3. 
  • Inhibition of apoptosis by Rv2456c through Nuclear factor-κB extends the survival of Mycobacterium tuberculosis. 
  • Inside-out Z rings--constriction with and without GTP hydrolysis. 
  • Insights into BAY 60-2770 activation and S-nitrosylation-dependent desensitization of soluble guanylyl cyclase via crystal structures of homologous nostoc H-NOX domain complexes. 
  • Interaction of MUC1 with beta-catenin modulates the Wnt target gene cyclinD1 in H. pylori-induced gastric cancer. 
  • Intracellular expression of Peptide fusions for demonstration of protein essentiality in bacteria. 
  • Intranasal vaccination with the recombinant Listeria monocytogenes ΔactA prfA* mutant elicits robust systemic and pulmonary cellular responses and secretory mucosal IgA. 
  • Invasive disease caused by nontuberculous mycobacteria, Tanzania. 
  • Investigation of the role of electrostatic charge in activation of the Escherichia coli response regulator CheY. 
  • Involvement of the S-layer proteins Hpi and SlpA in the maintenance of cell envelope integrity in Deinococcus radiodurans R1. 
  • Involvement of two putative alternative sigma factors in stress response of the radioresistant bacterium Deinococcus radiodurans. 
  • Ion channels: an open and shut case. 
  • Isolation and characterization of the replicon of a Thiobacillus intermedius plasmid. 
  • Isolation of a new RNA polymerase-binding protein from sporulating Bacillus subtilis. 
  • Kinetic analysis of the zinc-dependent deacetylase in the lipid A biosynthetic pathway. 
  • Kinetic characterization of Salmonella FliK-FlhB interactions demonstrates complexity of the Type III secretion substrate-specificity switch. 
  • Kinetic studies of tryptophan synthetase. Interaction of L-serine, indole, and tryptophan with the native enzyme. 
  • Kinetics and mechanism of exogenous anion exchange in FeFbpA-NTA: significance of periplasmic anion lability and anion binding activity of ferric binding protein A. 
  • Kinetics and mechanism of iron(III) complexation by ferric binding protein: the role of phosphate. 
  • Kinetics of iron release from ferric binding protein (FbpA): mechanistic implications in bacterial periplasm-to-cytosol Fe3+ transport. 
  • Kingella kingae expresses type IV pili that mediate adherence to respiratory epithelial and synovial cells. 
  • Lactobacillus reuteri DSM 20016 produces cobalamin-dependent diol dehydratase in metabolosomes and metabolizes 1,2-propanediol by disproportionation. 
  • Lambda transducing phages for the nalA gene of Escherichia coli and conditional lethal nalA mutations. 
  • Linked domain architectures allow for specialization of function in the FtsK/SpoIIIE ATPases of ESX secretion systems. 
  • Lipooligosaccharide is required for the generation of infectious elementary bodies in Chlamydia trachomatis. 
  • Liposome division by a simple bacterial division machinery. 
  • Liposome reconstitution and transport assay for recombinant transporters. 
  • Longitudinal characterization of synovial fluid biomarkers in the canine meniscectomy model of osteoarthritis. 
  • Low-shear modeled microgravity: a global environmental regulatory signal affecting bacterial gene expression, physiology, and pathogenesis. 
  • Maintenance of nitric oxide and redox homeostasis by the salmonella flavohemoglobin hmp. 
  • Mast cell activation by Mycobacterium tuberculosis: mediator release and role of CD48. 
  • Mast cell degranulation induced by type 1 fimbriated Escherichia coli in mice. 
  • Mast cell phagocytosis of FimH-expressing enterobacteria. 
  • Mechanism of 5'-directed excision in human mismatch repair. 
  • Mechanism of action of nalidixic acid: purification of Escherichia coli nalA gene product and its relationship to DNA gyrase and a novel nicking-closing enzyme. 
  • Mechanism of autophosphorylation of Escherichia coli nitrogen regulator II (NRII or NtrB): trans-phosphorylation between subunits. 
  • Mechanism of staphylococcal multiresistance plasmid replication origin assembly by the RepA protein. 
  • Mechanism of ubiquitin activation revealed by the structure of a bacterial MoeB-MoaD complex. 
  • Mechanisms of tolerance induced by an immunotoxin against CD3 epsilon in a rhesus kidney allograft model. 
  • Mechanistic study on the reaction of a radical SAM dehydrogenase BtrN by electron paramagnetic resonance spectroscopy. 
  • Membrane disruption by antimicrobial fatty acids releases low-molecular-weight proteins from Staphylococcus aureus. 
  • MetJ repressor interactions with DNA probed by in-cell NMR. 
  • Methylation of the FSHD syndrome-linked subtelomeric repeat in normal and FSHD cell cultures and tissues. 
  • Microbiological and genotypic analysis of methicillin-resistant Staphylococcus aureus bacteremia. 
  • Minimal determinants for binding activated G alpha from the structure of a G alpha(i1)-peptide dimer. 
  • Mismatch-containing oligonucleotide duplexes bound by the E. coli mutS-encoded protein. 
  • Modeling the physics of FtsZ assembly and force generation. 
  • Modified Hodge test versus indirect carbapenemase test: prospective evaluation of a phenotypic assay for detection of Klebsiella pneumoniae carbapenemase (KPC) in Enterobacteriaceae. 
  • Modulation of MutS ATP hydrolysis by DNA cofactors. 
  • Modulation of the binding of signal peptides to lipid bilayers by dipoles near the hydrocarbon-water interface. 
  • Molecular Genetic Analysis of Chlamydia Species. 
  • Molecular basis of ChvE function in sugar binding, sugar utilization, and virulence in Agrobacterium tumefaciens. 
  • Molecular dissection of an outbreak of carbapenem-resistant enterobacteriaceae reveals Intergenus KPC carbapenemase transmission through a promiscuous plasmid. 
  • Molecular insights into DNA binding and anchoring by the Bacillus subtilis sporulation kinetochore-like RacA protein. 
  • Molecular mechanism by which the nucleoid occlusion factor, SlmA, keeps cytokinesis in check. 
  • Multicenter study to determine disk diffusion and broth microdilution criteria for prediction of high- and low-level mupirocin resistance in Staphylococcus aureus. 
  • Multicentre surveillance of the prevalence and molecular epidemiology of macrolide resistance among pharyngeal isolates of group A streptococci in the USA. 
  • Multifactorial determinants of protein expression in prokaryotic open reading frames. 
  • Multifunctional analysis of Chlamydia-specific genes in a yeast expression system. 
  • MutL traps MutS at a DNA mismatch. 
  • MutS mediates heteroduplex loop formation by a translocation mechanism. 
  • Mutagenesis studies of substrate recognition and catalysis in the sortase A transpeptidase from Staphylococcus aureus. 
  • Mutants of FtsZ targeting the protofilament interface: effects on cell division and GTPase activity. 
  • Mutation detection with MutH, MutL, and MutS mismatch repair proteins. 
  • Mutational analysis of active site residues in the Staphylococcus aureus transpeptidase SrtA. 
  • Mutations in hemG mediate resistance to salicylidene acylhydrazides, demonstrating a novel link between protoporphyrinogen oxidase (HemG) and Chlamydia trachomatis infectivity. 
  • NMR and XAS reveal an inner-sphere metal binding site in the P4 helix of the metallo-ribozyme ribonuclease P. 
  • Negative autoregulation of cysB in Salmonella typhimurium: in vitro interactions of CysB protein with the cysB promoter. 
  • Negative-stain electron microscopy of inside-out FtsZ rings reconstituted on artificial membrane tubules show ribbons of protofilaments. 
  • Neighborhood socio-economic characteristics, African ancestry, and Helicobacter pylori sero-prevalence. 
  • Neutrophil activation by nascent FimH subunits of type 1 fimbriae purified from the periplasm of Escherichia coli. 
  • New insights into Chlamydia intracellular survival mechanisms. 
  • Nine enzymes are required for assembly of the pacidamycin group of peptidyl nucleoside antibiotics. 
  • Order out of disorder: working cycle of an intrinsically unfolded chaperone. 
  • Organization of carboxysome genes in the thiobacilli. 
  • Orientation of LamB signal peptides in bilayers: influence of lipid probes on peptide binding and interpretation of fluorescence quenching data. 
  • Osmolyte-induced folding of an intrinsically disordered protein: folding mechanism in the absence of ligand. 
  • OxyR: a molecular code for redox-related signaling. 
  • Performance of Homologous and Heterologous Prime-Boost Immunization Regimens of Recombinant Adenovirus and Modified Vaccinia Virus Ankara Expressing an Ag85B-TB10.4 Fusion Protein against Mycobacterium tuberculosis. 
  • Peroxisome function regulates growth on glucose in the basidiomycete fungus Cryptococcus neoformans. 
  • Persistent bacteremia due to methicillin-resistant Staphylococcus aureus infection is associated with agr dysfunction and low-level in vitro resistance to thrombin-induced platelet microbicidal protein. 
  • Perturbation of Staphylococcus aureus gene expression by the enoyl-acyl carrier protein reductase inhibitor AFN-1252. 
  • Phylogeny of Wolbachia pipientis based on gltA, groEL and ftsZ gene sequences: clustering of arthropod and nematode symbionts in the F supergroup, and evidence for further diversity in the Wolbachia tree. 
  • Pleiotropic alterations in lipid metabolism in yeast sac1 mutants: relationship to "bypass Sec14p" and inositol auxotrophy. 
  • Pmp-like proteins Pls1 and Pls2 are secreted into the lumen of the Chlamydia trachomatis inclusion. 
  • Polarized secretion. 
  • Polymerization of Ftsz, a bacterial homolog of tubulin. is assembly cooperative? 
  • Probing bacterial gene expression within host cells. 
  • Probing for Binding Regions of the FtsZ Protein Surface through Site-Directed Insertions: Discovery of Fully Functional FtsZ-Fluorescent Proteins. 
  • Probing the domain structure of FtsZ by random truncation and insertion of GFP. 
  • Prokaryotic transcription regulators: more than just the helix-turn-helix motif. 
  • Protein electron transfer rates set by the bridging secondary and tertiary structure. 
  • Protein fabrication automation. 
  • Protein kinase A operates a molecular switch that governs yeast pseudohyphal differentiation. 
  • Protein kinetics: structures of intermediates and reaction mechanism from time-resolved x-ray data. 
  • Protein loop closure using orientational restraints from NMR data. 
  • Protein nanotechnology: the new frontier in biosciences. 
  • Proteomic analysis of an unculturable bacterial endosymbiont (Blochmannia) reveals high abundance of chaperonins and biosynthetic enzymes. 
  • Protofilaments and rings, two conformations of the tubulin family conserved from bacterial FtsZ to alpha/beta and gamma tubulin. 
  • Purification and assembly of FtsZ. 
  • Quantitative immunoassay of anti-La antibodies using purified recombinant La antigen. 
  • Quantitative proteomics reveals metabolic and pathogenic properties of Chlamydia trachomatis developmental forms. 
  • Quenching of DNA cross-link precursors of chloroethylnitrosoureas and attenuation of DNA interstrand cross-linking by glutathione. 
  • Quorum-sensing regulation of a copper toxicity system in Pseudomonas aeruginosa. 
  • Rapid assembly dynamics of the Escherichia coli FtsZ-ring demonstrated by fluorescence recovery after photobleaching. 
  • Rapid dendritic transport of TGN38, a putative cargo receptor. 
  • Rapid determination of protein folds using residual dipolar couplings. 
  • Rapid in vitro assembly of Caulobacter crescentus FtsZ protein at pH 6.5 and 7.2. 
  • Rapid molecular detection of tuberculosis and rifampin resistance. 
  • Re-design of Rhodobacter sphaeroides dimethyl sulfoxide reductase. Enhancement of adenosine N1-oxide reductase activity. 
  • Reassessing the role of the secreted protease CPAF in Chlamydia trachomatis infection through genetic approaches. 
  • Receptor-associated protein binding blocks ubiquitinylation of the low density lipoprotein receptor-related protein. 
  • Recombinant Rhodobacter capsulatus xanthine dehydrogenase, a useful model system for the characterization of protein variants leading to xanthinuria I in humans. 
  • Reconstitution of contractile FtsZ rings in liposomes. 
  • Reconstitution of protein translocation from detergent-solubilized Escherichia coli inverted vesicles: PrlA protein-deficient vesicles efficiently translocate precursor proteins. 
  • Reduced susceptibility of Staphylococcus aureus to vancomycin and platelet microbicidal protein correlates with defective autolysis and loss of accessory gene regulator (agr) function. 
  • Regeneration Genetics. 
  • Regulation and action of the bacterial enhancer-binding protein AAA+ domains. 
  • Regulation of HIV-1 gene expression. 
  • Regulation of iron transport related genes by boron in the marine bacterium Marinobacter algicola DG893. 
  • Relative gene expression quantification in a fungal gas-phase biofilter. 
  • Residue threonine-149 of the Salmonella typhimurium CysB transcription activator: mutations causing constitutive expression of positively regulated genes of the cysteine regulon. 
  • Reversal of acute allograft rejection using immunotoxin. 
  • Risk factors for and estimated incidence of community-associated Clostridium difficile infection, North Carolina, USA. 
  • Role of Pseudomonas aeruginosa dinB-encoded DNA polymerase IV in mutagenesis. 
  • Salmonella typhimurium impedes innate immunity with a mast-cell-suppressing protein tyrosine phosphatase, SptP. 
  • Segrosome structure revealed by a complex of ParR with centromere DNA. 
  • Selection of strains for quality assessment of the disk induction method for detection of inducible clindamycin resistance in Staphylococci: a CLSI collaborative study. 
  • Sequence context of indel mutations and their effect on protein evolution in a bacterial endosymbiont. 
  • Shift in S-layer protein expression responsible for antigenic variation in Campylobacter fetus. 
  • Signal discrimination by differential regulation of protein stability in quorum sensing. 
  • Signatures of protein-DNA recognition in free DNA binding sites. 
  • Sinorhizobium meliloti phospholipase C required for lipid remodeling during phosphorus limitation. 
  • Site-directed mutagenesis studies of the high-affinity streptavidin-biotin complex: contributions of tryptophan residues 79, 108, and 120. 
  • SlmA forms a higher-order structure on DNA that inhibits cytokinetic Z-ring formation over the nucleoid. 
  • Solubilization of tricalcium phosphate by P(3HB) accumulating Azotobacter chroococcum MAL-201. 
  • Sortase ligation enables homogeneous GPCR phosphorylation to reveal diversity in β-arrestin coupling. 
  • Sortase transpeptidases: insights into mechanism, substrate specificity, and inhibition. 
  • Sortase-catalyzed initiator attachment enables high yield growth of a stealth polymer from the C terminus of a protein. 
  • Specificity of the type II secretion systems of enterotoxigenic Escherichia coli and Vibrio cholerae for heat-labile enterotoxin and cholera toxin. 
  • Split tolerance induced by immunotoxin in a rhesus kidney allograft model. 
  • Staphylococcus aureus sortase A contributes to the Trojan horse mechanism of immune defense evasion with its intrinsic resistance to Cys184 oxidation. 
  • Straight and curved conformations of FtsZ are regulated by GTP hydrolysis. 
  • Stress-induced outer membrane vesicle production by Pseudomonas aeruginosa. 
  • Structural analysis of semi-specific oligosaccharide recognition by a cellulose-binding protein of thermotoga maritima reveals adaptations for functional diversification of the oligopeptide periplasmic binding protein fold. 
  • Structural and Biochemical Characterization of the Francisella tularensis Pathogenicity Regulator, Macrophage Locus Protein A (MglA). 
  • Structural and Functional Analyses Reveal Insights into the Molecular Properties of the Escherichia coli Z Ring Stabilizing Protein, ZapC. 
  • Structural basis of multifunctional bovine mitochondrial cytochrome bc1 complex. 
  • Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters. 
  • Structural basis of pilus subunit recognition by the PapD chaperone. 
  • Structural basis of selection and thermostability of laboratory evolved Bacillus subtilis lipase. 
  • Structural characterization of the late competence protein ComFB from Bacillus subtilis. 
  • Structural determinants for signal sequence function in the mammalian endoplasmic reticulum. 
  • Structural evidence that the P/Q domain of ZipA is an unstructured, flexible tether between the membrane and the C-terminal FtsZ-binding domain. 
  • Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides. 
  • Structural genomics of Pyrococcus furiosus: X-ray crystallography reveals 3D domain swapping in rubrerythrin. 
  • Structural insights into inhibition of lipid I production in bacterial cell wall synthesis. 
  • Structural mechanism of ATP-induced polymerization of the partition factor ParF: implications for DNA segregation. 
  • Structural mechanism of the simultaneous binding of two drugs to a multidrug-binding protein. 
  • Structural mechanism of transcription regulation of the Staphylococcus aureus multidrug efflux operon mepRA by the MarR family repressor MepR. 
  • Structural mechanisms of QacR induction and multidrug recognition. 
  • Structure and DNA-binding traits of the transition state regulator AbrB. 
  • Structure and functional properties of the Bacillus subtilis transcriptional repressor Rex. 
  • Structure of a trimeric bacterial microcompartment shell protein, EtuB, associated with ethanol utilization in Clostridium kluyveri. 
  • Structure of an OhrR-ohrA operator complex reveals the DNA binding mechanism of the MarR family. 
  • Structure of the Z Ring-associated Protein, ZapD, Bound to the C-terminal Domain of the Tubulin-like Protein, FtsZ, Suggests Mechanism of Z Ring Stabilization through FtsZ Cross-linking. 
  • Structure of the deacetylase LpxC bound to the antibiotic CHIR-090: Time-dependent inhibition and specificity in ligand binding. 
  • Structure, inhibition, and regulation of essential lipid A enzymes. 
  • Structure-based design of robust glucose biosensors using a Thermotoga maritima periplasmic glucose-binding protein. 
  • Structures of BmrR-drug complexes reveal a rigid multidrug binding pocket and transcription activation through tyrosine expulsion. 
  • Structures of partition protein ParA with nonspecific DNA and ParB effector reveal molecular insights into principles governing Walker-box DNA segregation. 
  • Structures of regulatory machinery reveal novel molecular mechanisms controlling B. subtilis nitrogen homeostasis. 
  • Structures of the activator of K. pneumonia biofilm formation, MrkH, indicates PilZ domains involved in c-di-GMP and DNA binding. 
  • Structures of the nucleoid occlusion protein SlmA bound to DNA and the C-terminal domain of the cytoskeletal protein FtsZ. 
  • Structures of three polycystic kidney disease-like domains from Clostridium histolyticum collagenases ColG and ColH. 
  • Studies on the biosynthesis of the lipodepsipeptide antibiotic Ramoplanin A2. 
  • Subspecific differentiation of Mycobacterium avium complex strains by automated sequencing of a region of the gene (hsp65) encoding a 65-kilodalton heat shock protein. 
  • Substrate recognition by the EcoRI endonuclease. 
  • SulA inhibits assembly of FtsZ by a simple sequestration mechanism. 
  • Suppression of hepatitis B virus DNA accumulation in chronically infected cells using a bacterial CRISPR/Cas RNA-guided DNA endonuclease. 
  • Suprastructures and dynamic properties of Mycobacterium tuberculosis FtsZ. 
  • SymROP: ROP protein with identical helices redesigned by all-atom contact analysis and molecular dynamics. 
  • Synthesis and preliminary biological evaluation of (3-iodobenzoyl)norbiotinamide and ((5-iodo-3-pyridinyl)carbonyl)norbiotinamide: two radioiodinated biotin conjugates with improved stability. 
  • Synthesis of empty bacterial microcompartments, directed organelle protein incorporation, and evidence of filament-associated organelle movement. 
  • T7-induced DNA polymerase. Requirement for thioredoxin sulfhydryl groups. 
  • Tandem mass spectrometry acquisition approaches to enhance identification of protein-protein interactions using low-energy collision-induced dissociative chemical crosslinking reagents. 
  • Tetrameric c-di-GMP mediates effective transcription factor dimerization to control Streptomyces development. 
  • The ABCDs of periplasmic copper trafficking. 
  • The C-terminal linker of Escherichia coli FtsZ functions as an intrinsically disordered peptide. 
  • The Chlamydia protease CPAF regulates host and bacterial proteins to maintain pathogen vacuole integrity and promote virulence. 
  • The Chlamydia trachomatis Inclusion Membrane Protein CpoS Counteracts STING-Mediated Cellular Surveillance and Suicide Programs. 
  • The Chlamydia trachomatis Protease CPAF Contains a Cryptic PDZ-Like Domain with Similarity to Human Cell Polarity and Tight Junction PDZ-Containing Proteins. 
  • The Chlamydia type III secretion system C-ring engages a chaperone-effector protein complex. 
  • The Chloroplast Tubulin Homologs FtsZA and FtsZB from the Red Alga Galdieria sulphuraria Co-assemble into Dynamic Filaments. 
  • The Closing Mechanism of DNA Polymerase I at Atomic Resolution. 
  • The DNA-binding homeo domain of the Oct-2 protein. 
  • The Drosophila claret segregation protein is a minus-end directed motor molecule. 
  • The FtsZ protofilament and attachment of ZipA--structural constraints on the FtsZ power stroke. 
  • The GO system prevents ROS-induced mutagenesis and killing in Pseudomonas aeruginosa. 
  • The Haemophilus influenzae hFbpABC Fe3+ transporter: analysis of the membrane permease and development of a gallium-based screen for mutants. 
  • The MetJ regulon in gammaproteobacteria determined by comparative genomics methods. 
  • The MotA transcriptional activator of bacteriophage T4 binds to its specific DNA site as a monomer. 
  • The Mycobacterium tuberculosis 71-kDa heat-shock protein induces proliferation and cytokine secretion by murine gut intraepithelial lymphocytes. 
  • The Streptomyces master regulator BldD binds c-di-GMP sequentially to create a functional BldD2-(c-di-GMP)4 complex. 
  • The TetR family of transcriptional repressors. 
  • The UDP-diacylglucosamine pyrophosphohydrolase LpxH in lipid A biosynthesis utilizes Mn2+ cluster for catalysis. 
  • The backbone structure of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein is essentially identical to its mesophilic E. coli homolog. 
  • The biosynthesis of molybdopterin in Escherichia coli. Purification and characterization of the converting factor. 
  • The crystal structure of a thermophilic glucose binding protein reveals adaptations that interconvert mono and di-saccharide binding sites. 
  • The crystal structure of the TetR family transcriptional repressor SimR bound to DNA and the role of a flexible N-terminal extension in minor groove binding. 
  • The cyclophilin-like domain of Ran-binding protein-2 modulates selectively the activity of the ubiquitin-proteasome system and protein biogenesis. 
  • The development of therapeutic and preventive vaccines for gastric cancer and Helicobacter pylori. 
  • The discovery of the prokaryotic cytoskeleton: 25th anniversary. 
  • The effect of osmotic stress on the production of nukacin ISK-1 from Staphylococcus warneri ISK-1. 
  • The filamentous bacteriophage assembly proteins require the bacterial SecA protein for correct localization to the membrane. 
  • The importance of binding energy in catalysis of hydride transfer by UDP-galactose 4-epimerase: a 13C and 15N NMR and kinetic study. 
  • The importance of repairing stalled replication forks. 
  • The influence of the synergistic anion on iron chelation by ferric binding protein, a bacterial transferrin. 
  • The location of the carotenoid in the B800--850 light-harvesting pigment--protein complex from Rhodopseudomonas capsulata. 
  • The molecular mechanisms of allosteric mutations impairing MepR repressor function in multidrug-resistant strains of Staphylococcus aureus. 
  • The obligate intracellular pathogen Chlamydia trachomatis targets host lipid droplets. 
  • The posttranslational modification cascade to the thiopeptide berninamycin generates linear forms and altered macrocyclic scaffolds. 
  • The potential role of alpha 2-macroglobulin in the control of cysteine proteinases (gingipains) from Porphyromonas gingivalis. 
  • The relationship between ligand-binding thermodynamics and protein-ligand interaction forces measured by atomic force microscopy. 
  • The role of FeS clusters for molybdenum cofactor biosynthesis and molybdoenzymes in bacteria. 
  • The role of the supernumerary subunit of Rhodobacter sphaeroides cytochrome bc1 complex. 
  • The roles of positive and negative selection in the molecular evolution of insect endosymbionts. 
  • The staphylococcal QacR multidrug regulator binds a correctly spaced operator as a pair of dimers. 
  • The straight and curved conformation of FtsZ protofilaments-evidence for rapid exchange of GTP into the curved protofilament. 
  • The structural mechanism for transcription activation by MerR family member multidrug transporter activation, N terminus. 
  • The structure of a high fidelity DNA polymerase bound to a mismatched nucleotide reveals an "ajar" intermediate conformation in the nucleotide selection mechanism. 
  • The symmetrical structure of structural maintenance of chromosomes (SMC) and MukB proteins: long, antiparallel coiled coils, folded at a flexible hinge. 
  • The triple threat of cryptococcosis: it's the body site, the strain, and/or the host. 
  • The tyrosine corner: a feature of most Greek key beta-barrel proteins. 
  • The vibrio cholerae hybrid sensor kinase VieS contributes to motility and biofilm regulation by altering the cyclic diguanylate level. 
  • Thermal stability of self-assembled peptide vaccine materials. 
  • Thermodynamic evaluation of binding interactions in the methionine repressor system of Escherichia coli using isothermal titration calorimetry. 
  • Thermodynamic stability measurements on multimeric proteins using a new H/D exchange- and matrix-assisted laser desorption/ionization (MALDI) mass spectrometry-based method. 
  • Three-in-one chromatography-free purification, tag removal, and site-specific modification of recombinant fusion proteins using sortase A and elastin-like polypeptides. 
  • Tissue plasminogen activator (tPA) signal sequence enhances immunogenicity of MVA-based vaccine against tuberculosis. 
  • Tn5-mediated bleomycin resistance in Escherichia coli requires the expression of host genes. 
  • Total chemical synthesis of the B1 domain of protein L from Peptostreptococcus magnus. 
  • Trafficking patterns of beta-arrestin and G protein-coupled receptors determined by the kinetics of beta-arrestin deubiquitination. 
  • Transcription-associated mutation of lasR in Pseudomonas aeruginosa. 
  • Transfer of CD8+ T cell memory using Bcl-2 as a marker. 
  • Transmission of methicillin-resistant Staphylococcus aureus between human and hamster. 
  • Treatment with immunotoxin. 
  • Tuberculous granuloma induction via interaction of a bacterial secreted protein with host epithelium. 
  • Two CDC42 paralogues modulate Cryptococcus neoformans thermotolerance and morphogenesis under host physiological conditions. 
  • Two proteins encoded at the chlA locus constitute the converting factor of Escherichia coli chlA1. 
  • Two-dimensional crystallization and projection structure of KcsA potassium channel. 
  • Two-dimensional protein crystallization via metal-ion coordination by naturally occurring surface histidines. 
  • Type 1 fimbrial shafts of Escherichia coli and Klebsiella pneumoniae influence sugar-binding specificities of their FimH adhesins. 
  • Tyrosine-dependent basolateral targeting of human connexin43-eYFP in Madin-Darby canine kidney cells can be disrupted by the oculodentodigital dysplasia mutation L90V. 
  • Use of monoclonal antibodies to probe subunit- and polymer-specific epitopes of 987P fimbriae of Escherichia coli. 
  • Variation of molecular alignment as a means of resolving orientational ambiguities in protein structures from dipolar couplings. 
  • Vinyl sulfones: inhibitors of SrtA, a transpeptidase required for cell wall protein anchoring and virulence in Staphylococcus aureus. 
  • Visualizing reaction pathways in photoactive yellow protein from nanoseconds to seconds. 
  • Whole genome re-sequencing to identify suppressor mutations of mutant and foreign Escherichia coli FtsZ. 
  • Widespread recombination throughout Wolbachia genomes. 
  • Yield of stool culture with isolate toxin testing versus a two-step algorithm including stool toxin testing for detection of toxigenic Clostridium difficile. 
• 

  Keywords of People

  • Erickson, Harold Paul, James B. Duke Professor of Cell Biology, Biomedical Engineering
  • Ferreira, Paulo Alexandre, Associate Professor in Ophthalmology, Pathology
  • Gottlin, Elizabeth B., Assistant Professor in Radiology, Radiology
  • Kuehn, Margarethe Joanna, Associate Professor of Biochemistry, Molecular Genetics and Microbiology
  • Schmid, Amy K., Associate Professor of Biology, Duke Science & Society
  • Soderling, Scott Haydn, Professor in Cell Biology, Cell Biology
  • Zhang, Zhiquan, Assistant Professor in Anesthesiology, Anesthesiology