Bacterial Proteins

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  Subject Areas on Research

  • 50 million years of genomic stasis in endosymbiotic bacteria. 
  • A Bacterial Chromosome Structuring Protein Binds Overtwisted DNA to Stimulate Type II Topoisomerases and Enable DNA Replication. 
  • A Bayesian approach for determining protein side-chain rotamer conformations using unassigned NOE data. 
  • A Bgl II polymorphism detected by LDR152 [D19S19]. 
  • A CRISPR-Cas system enhances envelope integrity mediating antibiotic resistance and inflammasome evasion. 
  • A Chlamydia effector combining deubiquitination and acetylation activities induces Golgi fragmentation. 
  • A DNA mimic: the structure and mechanism of action for the anti-repressor protein AbbA. 
  • A Pseudomonas syringae type III effector suppresses cell wall-based extracellular defense in susceptible Arabidopsis plants. 
  • A Unified Model for Treadmilling and Nucleation of Single-Stranded FtsZ Protofilaments. 
  • A bacterial kinase phosphorylates OSK1 to suppress stomatal immunity in rice. 
  • A bacterial tyrosine phosphatase inhibits plant pattern recognition receptor activation. 
  • A bacterial virulence protein suppresses host innate immunity to cause plant disease. 
  • A closely-related clade of globally distributed bloom-forming cyanobacteria within the Nostocales. 
  • A combination of independent transcriptional regulators shapes bacterial virulence gene expression during infection. 
  • A common clathrin-mediated machinery co-ordinates cell-cell adhesion and bacterial internalization. 
  • A comparison of the constituent polypeptides of the B-800--850 light-harvesting pigment-protein complex from Rhodopseudomonas sphaeroides. 
  • A connection between stress and development in the multicellular prokaryote Streptomyces coelicolor A3(2). 
  • A conserved amino acid sequence directing intracellular type III secretion by Salmonella typhimurium. 
  • A cut above the other caspases. 
  • A direct link between carbohydrate utilization and virulence in the major human pathogen group A Streptococcus. 
  • A family of conserved bacterial effectors inhibits salicylic acid-mediated basal immunity and promotes disease necrosis in plants. 
  • A geometric arrangement algorithm for structure determination of symmetric protein homo-oligomers from NOEs and RDCs. 
  • A graphical method for analyzing distance restraints using residual dipolar couplings for structure determination of symmetric protein homo-oligomers. 
  • A human protein with antimutator activity. 
  • A naturally occurring hPMS2 mutation can confer a dominant negative mutator phenotype. 
  • A new H/D exchange- and mass spectrometry-based method for thermodynamic analysis of protein-DNA interactions. 
  • A noncanonical function of sortase enables site-specific conjugation of small molecules to lysine residues in proteins. 
  • A novel relaxase homologue is involved in chromosomal DNA processing for type IV secretion in Neisseria gonorrhoeae. 
  • A novel secretion apparatus for the assembly of adhesive bacterial pili. 
  • A pH-gated conformational switch regulates the phosphatase activity of bifunctional HisKA-family histidine kinases. 
  • A power-law dependence of bacterial invasion on mammalian host receptors. 
  • A pseudoknot in the 3' non-core region of the glmS ribozyme enhances self-cleavage activity. 
  • A quantitative, high-throughput screen for protein stability. 
  • A rapid fluorescence assay for FtsZ assembly indicates cooperative assembly with a dimer nucleus. 
  • A single acidic residue can guide binding site selection but does not govern QacR cationic-drug affinity. 
  • A solubility-enhancement tag (SET) for NMR studies of poorly behaving proteins. 
  • A strong effect of AT mutational bias on amino acid usage in Buchnera is mitigated at high-expression genes. 
  • A structural pathway for signaling in the E46Q mutant of photoactive yellow protein. 
  • A structure-based mechanism for drug binding by multidrug transporters. 
  • A thioesterase bypasses the requirement for exogenous fatty acids in the plsX deletion of Streptococcus pneumoniae. 
  • Abh and AbrB control of Bacillus subtilis antimicrobial gene expression. 
  • Abundance and genetic diversity of aerobic anoxygenic phototrophic bacteria of coastal regions of the pacific ocean. 
  • Activation of MAPK/ERK signaling by Burkholderia pseudomallei cycle inhibiting factor (Cif). 
  • Adenylate cyclase toxin (ACT) from Bordetella hinzii: characterization and differences from ACT of Bordetella pertussis. 
  • Adhesin presentation in bacteria requires molecular chaperones and ushers. 
  • Allergic reactions to E. coli L-asparaginase do not affect outcome in childhood B-precursor acute lymphoblastic leukemia: a Children's Oncology Group Study. 
  • Allosteric regulation of glycogen breakdown by the second messenger cyclic di-GMP. 
  • Amino acid permeases require COPII components and the ER resident membrane protein Shr3p for packaging into transport vesicles in vitro. 
  • Amplification of antigen-antibody interactions based on biotin labeled protein-streptavidin network complex using impedance spectroscopy. 
  • An ancestral mycobacterial effector promotes dissemination of infection. 
  • An economical and preparative orthogonal solid phase synthesis of fluorescein and rhodamine derivatized peptides: FRET substrates for the Staphylococcus aureus sortase SrtA transpeptidase reaction. 
  • An inner membrane dioxygenase that generates the 2-hydroxymyristate moiety of Salmonella lipid A. 
  • An undecaprenyl phosphate-aminoarabinose flippase required for polymyxin resistance in Escherichia coli. 
  • Analysis of experimental time-resolved crystallographic data by singular value decomposition. 
  • Analysis of phenylthiohydantoin amino acid mixtures for sequencing by thermospray liquid chromatography/mass spectrometry. 
  • Analysis of the substrate specificity of the Staphylococcus aureus sortase transpeptidase SrtA. 
  • Antagonism of toxigenic Clostridium difficile by nontoxigenic C. difficile. 
  • Antibody Responses to Streptococcus Gallolyticus Subspecies Gallolyticus Proteins in a Large Prospective Colorectal Cancer Cohort Consortium. 
  • Antioxidant enzyme expression in clinical isolates of Pseudomonas aeruginosa: identification of an atypical form of manganese superoxide dismutase. 
  • Apparent cooperative assembly of the bacterial cell division protein FtsZ demonstrated by isothermal titration calorimetry. 
  • Appearance of a ribonucleic acid polymerase-binding protein in asporogenous mutants of Bacillus subtilis. 
  • Application of singular value decomposition to the analysis of time-resolved macromolecular x-ray data. 
  • Aptamers: an emerging class of therapeutics. 
  • Arc/Arg3.1 translation is controlled by convergent N-methyl-D-aspartate and Gs-coupled receptor signaling pathways. 
  • Are mycoplasma membrane proteins affected by variations in membrane fatty acid composition? 
  • Assembly and molecular activities of the MutS tetramer. 
  • Assembly dynamics of FtsZ rings in Bacillus subtilis and Escherichia coli and effects of FtsZ-regulating proteins. 
  • Assembly dynamics of Mycobacterium tuberculosis FtsZ. 
  • Assembly of a chemically synthesized peptide of Escherichia coli type 1 fimbriae into fimbria-like antigenic structures. 
  • Assessment of a quantitative multiplex 5' nuclease real-time PCR for spotted fever and typhus group rickettsioses and Orientia tsutsugamushi. 
  • Assignment of the 1H, 13C and 15N resonances of the LpxC deacetylase from Aquifex aeolicus in complex with the substrate-analog inhibitor TU-514. 
  • Association of Helicobacter pylori infection and diet on the risk of gastric cancer: a case-control study in Hawaii. 
  • Atomic structures of tubulin and FtsZ. 
  • Bacteria establish an aqueous living space in plants crucial for virulence. 
  • Bacterial Nucleoid Occlusion: Multiple Mechanisms for Preventing Chromosome Bisection During Cell Division. 
  • Bacterial cell division protein FtsZ assembles into protofilament sheets and minirings, structural homologs of tubulin polymers. 
  • Bacterial effector activates jasmonate signaling by directly targeting JAZ transcriptional repressors. 
  • Bacterial infection remains a leading cause of death in both Western and developing world. Preface. 
  • Bacterial lipase and high-fat diets in canine exocrine pancreatic insufficiency: a new therapy of steatorrhea? 
  • Bacterial-host-cell tethers. 
  • Bacteriophage T4 UvsW protein is a helicase involved in recombination, repair and the regulation of DNA replication origins. 
  • Bacteriophage T7 Deoxyribonucleic acid replication in vitro. A protein of Escherichia coli required for bacteriophage T7 DNA polymerase activity. 
  • Bacteriophage T7 deoxyribonucleic acid replication invitro. Bacteriophage T7 DNA polymerase: an an emzyme composed of phage- and host-specific subunits. 
  • Beryllofluoride mimics phosphorylation of NtrC and other bacterial response regulators. 
  • Bidirectional excision in methyl-directed mismatch repair. 
  • Bimodal activation of SMC ATPase by intra- and inter-molecular interactions. 
  • Binding of MetJ repressor to specific and nonspecific DNA and effect of S-adenosylmethionine on these interactions. 
  • Binding of the global response regulator protein CovR to the sag promoter of Streptococcus pyogenes reveals a new mode of CovR-DNA interaction. 
  • Biochemical and structural insights into bacterial organelle form and biogenesis. 
  • Biochemical role of the Cryptococcus neoformans ADE2 protein in fungal de novo purine biosynthesis. 
  • Biochemistry. Photosynthesis from the protein's perspective. 
  • Biological functions and biogenesis of secreted bacterial outer membrane vesicles. 
  • Biosynthesis of undecaprenyl phosphate-galactosamine and undecaprenyl phosphate-glucose in Francisella novicida. 
  • Blastomyces dermatitidis chemotactic factor: kinetics of production and biological characterization evaluated by a modified neutrophil chemotaxis assay. 
  • Bonds between fibronectin and fibronectin-binding proteins on Staphylococcus aureus and Lactococcus lactis. 
  • Borate as a synergistic anion for Marinobacter algicola ferric binding protein, FbpA: a role for boron in iron transport in marine life. 
  • Bordetella pertussis FbpA binds both unchelated iron and iron siderophore complexes. 
  • BtubA-BtubB heterodimer is an essential intermediate in protofilament assembly. 
  • C-C bond forming radical SAM enzymes involved in the construction of carbon skeletons of cofactors and natural products. 
  • C-terminally truncated derivatives of Escherichia coli Hfq are proficient in riboregulation. 
  • CNS1 encodes an essential p60/Sti1 homolog in Saccharomyces cerevisiae that suppresses cyclophilin 40 mutations and interacts with Hsp90. 
  • Caenorhabditis elegans-based screen identifies Salmonella virulence factors required for conserved host-pathogen interactions. 
  • Carbapenemase-Encoding Gene Copy Number Estimator (CCNE): a Tool for Carbapenemase Gene Copy Number Estimation. 
  • Cas9 loosens its grip on off-target sites. 
  • Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death. 
  • Caulobacter crescentus Adapts to Phosphate Starvation by Synthesizing Anionic Glycoglycerolipids and a Novel Glycosphingolipid. 
  • Cell division without FtsZ--a variety of redundant mechanisms. 
  • Cellular cytoskeleton dynamics modulates non-viral gene delivery through RhoGTPases 
  • Chaperone-assisted assembly and molecular architecture of adhesive pili. 
  • Chapter 1 - Tubular liposomes with variable permeability for reconstitution of FtsZ rings. 
  • Characterisation of PduS, the pdu metabolosome corrin reductase, and evidence of substructural organisation within the bacterial microcompartment. 
  • Characterization and structure of the manganese-responsive transcriptional regulator ScaR. 
  • Characterization of Escherichia coli MoeB and its involvement in the activation of molybdopterin synthase for the biosynthesis of the molybdenum cofactor. 
  • Characterization of Mycobacterium montefiorense sp. nov., a novel pathogenic Mycobacterium from moray eels that is related to Mycobacterium triplex. 
  • Characterization of an iron-sulfur cluster assembly protein (ISU1) from Schizosaccharomyces pombe. 
  • Characterization of the DNA- and metal-binding properties of Vibrio anguillarum fur reveals conservation of a structural Zn(2+) ion. 
  • Characterization of the SarA virulence gene regulator of Staphylococcus aureus. 
  • Characterization of the multiple transferable resistance repressor, MtrR, from Neisseria gonorrhoeae. 
  • Chemical logic of MraY inhibition by antibacterial nucleoside natural products. 
  • Chemical shift assignments and secondary structure prediction of the phosphorelay protein VanU from Vibrio anguillarum. 
  • Choreography of the transcriptome, photophysiology, and cell cycle of a minimal photoautotroph, prochlorococcus. 
  • Chromophore conformation and the evolution of tertiary structural changes in photoactive yellow protein. 
  • Chromosomally located gene fusions constructed in Acinetobacter sp. ADP1 for the detection of salicylate. 
  • Citrus CsACD2 Is a Target of Candidatus Liberibacter Asiaticus in Huanglongbing Disease. 
  • Clathrin phosphorylation is required for actin recruitment at sites of bacterial adhesion and internalization. 
  • Cloned Erwinia chrysanthemi out genes enable Escherichia coli to selectively secrete a diverse family of heterologous proteins to its milieu. 
  • Clostridium difficile infection and treatment in the pediatric inflammatory bowel disease population. 
  • Clostridium taeniosporum spore ribbon-like appendage structure, composition and genes. 
  • Co-evolving motions at protein-protein interfaces of two-component signaling systems identified by covariance analysis. 
  • Coculturing of Mosquito-Microbiome Bacteria Promotes Heme Degradation in Elizabethkingia anophelis. 
  • Colonial differentiation in Streptomyces coelicolor depends on translation of a specific codon within the adpA gene. 
  • Comparative transcriptome analysis of the CO2 sensing pathway via differential expression of carbonic anhydrase in Cryptococcus neoformans. 
  • Comparison of acellular pertussis-diphtheria-tetanus toxoids and Haemophilus influenzae type b vaccines administered separately vs. combined in younger vs. older toddlers. 
  • Comparison of seven techniques for typing international epidemic strains of Clostridium difficile: restriction endonuclease analysis, pulsed-field gel electrophoresis, PCR-ribotyping, multilocus sequence typing, multilocus variable-number tandem-repeat analysis, amplified fragment length polymorphism, and surface layer protein A gene sequence typing. 
  • Comparison of the safety and immunogenicity of an investigational and a licensed quadrivalent meningococcal conjugate vaccine in children 2-10 years of age. 
  • Comparison of two rapid assays for Clostridium difficile Common antigen and a C difficile toxin A/B assay with the cell culture neutralization assay. 
  • Comprehensive two-dimensional high-performance liquid chromatography for the isolation of overexpressed proteins and proteome mapping. 
  • Conformational changes of FtsZ reported by tryptophan mutants. 
  • Conformational changes of purine repressor DNA-binding domain upon complexation with DNA. 
  • Conformational kinetics reveals affinities of protein conformational states. 
  • Conformational plasticity of the coiled-coil domain of BmrR is required for bmr operator binding: the structure of unliganded BmrR. 
  • Conservation of structure and location of Rhizobium meliloti and Klebsiella pneumoniae nifB genes. 
  • Conservation of the D-mannose-adhesion protein among type 1 fimbriated members of the family Enterobacteriaceae. 
  • Conservation of the chitin utilization pathway in the Vibrionaceae. 
  • Constitutive expression of a groEL-related protein on the surface of human gamma/delta cells. 
  • Control of protein-ligand recognition using a stimuli-responsive polymer. 
  • Controlling mRNA stability and translation with the CRISPR endoribonuclease Csy4. 
  • Conversion of a maltose receptor into a zinc biosensor by computational design. 
  • Conversion of compatible plant-pathogen interactions into incompatible interactions by expression of the Pseudomonas syringae pv. syringae 61 hrmA gene in transgenic tobacco plants. 
  • Copper Influences the Antibacterial Outcomes of a β-Lactamase-Activated Prochelator against Drug-Resistant Bacteria. 
  • Copper complexes containing thiosemicarbazones derived from 6-nitropiperonal: Antimicrobial and biophysical properties. 
  • Correlation of cefoxitin MICs with the presence of mecA in Staphylococcus spp. 
  • CovR activation of the dipeptide permease promoter (PdppA) in Group A Streptococcus. 
  • Coxiella burnetii effector proteins that localize to the parasitophorous vacuole membrane promote intracellular replication. 
  • Critical role of the RpoE stress response pathway in polymyxin resistance of Escherichia coli. 
  • Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex. 
  • Cryo-EM Structures of the Magnesium Channel CorA Reveal Symmetry Break upon Gating. 
  • Crystal structure of HPr kinase/phosphatase from Mycoplasma pneumoniae. 
  • Crystal structure of LacI member, PurR, bound to DNA: minor groove binding by alpha helices. 
  • Crystal structure of MraY, an essential membrane enzyme for bacterial cell wall synthesis. 
  • Crystal structure of MtaN, a global multidrug transporter gene activator. 
  • Crystal structure of Streptococcus pyogenes sortase A: implications for sortase mechanism. 
  • Crystal structure of a photoactive yellow protein from a sensor histidine kinase: conformational variability and signal transduction. 
  • Crystal structure of activated CheY. Comparison with other activated receiver domains. 
  • Crystal structure of an activated response regulator bound to its target. 
  • Crystal structure of the Bacillus subtilis anti-alpha, global transcriptional regulator, Spx, in complex with the alpha C-terminal domain of RNA polymerase. 
  • Crystal structure of the MOP flippase MurJ in an inward-facing conformation. 
  • Crystal structure of the gephyrin-related molybdenum cofactor biosynthesis protein MogA from Escherichia coli. 
  • Crystal structure of the lactose operon repressor and its complexes with DNA and inducer. 
  • Crystal structure of the transcription activator BmrR bound to DNA and a drug. 
  • Crystal structures of QacR-diamidine complexes reveal additional multidrug-binding modes and a novel mechanism of drug charge neutralization. 
  • Crystal structures of SarA, a pleiotropic regulator of virulence genes in S. aureus. 
  • Crystallization and preliminary X-ray analysis of an Escherichia coli purine repressor-hypoxanthine-DNA complex. 
  • Crystallization and preliminary X-ray crystallographic investigations on several thermostable forms of a Bacillus subtilis lipase. 
  • Crystallization and preliminary X-ray diffraction studies on the DNA-binding domain of the multidrug transporter activation protein (MtaN) from Bacillus subtilis. 
  • Crystallization and preliminary X-ray studies on the co-repressor binding domain of the Escherichia coli purine repressor. 
  • Crystallization of the bifunctional biotin operon repressor. 
  • Crystallization, preliminary X-ray analysis and biophysical characterization of HPr kinase/phosphatase of Mycoplasma pneumoniae. 
  • Curative Treatment of Severe Gram-Negative Bacterial Infections by a New Class of Antibiotics Targeting LpxC. 
  • Curved FtsZ protofilaments generate bending forces on liposome membranes. 
  • Cyclopropane Modification of Trehalose Dimycolate Drives Granuloma Angiogenesis and Mycobacterial Growth through Vegf Signaling. 
  • Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf. 
  • Cytoskeleton. Evolution in bacteria. 
  • DNA damage responses in prokaryotes: regulating gene expression, modulating growth patterns, and manipulating replication forks. 
  • DNA mismatch repair: functions and mechanisms. 
  • DNA sequence and genetic characterization of plasmid pFQ11 from Frankia alni strain CpI1. 
  • Daptomycin-resistant Enterococcus faecalis diverts the antibiotic molecule from the division septum and remodels cell membrane phospholipids. 
  • Deciphering the molecular basis of multidrug recognition: crystal structures of the Staphylococcus aureus multidrug binding transcription regulator QacR. 
  • Definition of a metal-dependent/Li(+)-inhibited phosphomonoesterase protein family based upon a conserved three-dimensional core structure. 
  • Derivatives of plant phenolic compound affect the type III secretion system of Pseudomonas aeruginosa via a GacS-GacA two-component signal transduction system. 
  • Detection of Clostridium difficile as a routine diagnosis: comparison of real-time PCR and enzyme immunoassay. 
  • Detection of Cytosolic Shigella flexneri via a C-Terminal Triple-Arginine Motif of GBP1 Inhibits Actin-Based Motility. 
  • Development of DNA Vaccine Targeting E6 and E7 Proteins of Human Papillomavirus 16 (HPV16) and HPV18 for Immunotherapy in Combination with Recombinant Vaccinia Boost and PD-1 Antibody. 
  • Development of a high-performance liquid chromatography assay and revision of kinetic parameters for the Staphylococcus aureus sortase transpeptidase SrtA. 
  • Diagnostic accuracy of leptospirosis whole-cell lateral flow assays: a systematic review and meta-analysis. 
  • Differences in antibody levels to H. pylori virulence factors VacA and CagA among African Americans and whites in the Southeast USA. 
  • Differential actions of PAR2 and PAR1 in stimulating human endothelial cell exocytosis and permeability: the role of Rho-GTPases. 
  • Differential and simultaneous adenosine di- and triphosphate binding by MutS. 
  • Difluoromethylornithine is a novel inhibitor of Helicobacter pylori growth, CagA translocation, and interleukin-8 induction. 
  • Dihydrophenylalanine: a prephenate-derived Photorhabdus luminescens antibiotic and intermediate in dihydrostilbene biosynthesis. 
  • Direct analysis of backbone-backbone hydrogen bond formation in protein folding transition states. 
  • Direct binding of polymeric GBP1 to LPS disrupts bacterial cell envelope functions. 
  • Disruption of Arp2/3 results in asymmetric structural plasticity of dendritic spines and progressive synaptic and behavioral abnormalities. 
  • Dissemination of an Enterococcus Inc18-Like vanA plasmid associated with vancomycin-resistant Staphylococcus aureus. 
  • Distinct MutS DNA-binding modes that are differentially modulated by ATP binding and hydrolysis. 
  • Distinct single amino acid replacements in the control of virulence regulator protein differentially impact streptococcal pathogenesis. 
  • Diverse mechanisms of resistance to Pseudomonas syringae in a thousand natural accessions of Arabidopsis thaliana. 
  • Division of labour between Myc and G1 cyclins in cell cycle commitment and pace control. 
  • Domain Organization in the 54-kDa Subunit of the Chloroplast Signal Recognition Particle. 
  • Domain unfolding plays a role in superfibronectin formation. 
  • Dual impact of elevated temperature on plant defence and bacterial virulence in Arabidopsis. 
  • Dynamics of HIV neutralization by a microbicide formulation layer: biophysical fundamentals and transport theory. 
  • Dynamin and FtsZ. Missing links in mitochondrial and bacterial division. 
  • Effect of bacterial or porcine lipase with low- or high-fat diets on nutrient absorption in pancreatic-insufficient dogs. 
  • Effect of isopropyl-beta-D-thiogalactopyranosid induction of the lac operon on the specificity of spontaneous and doxorubicin-induced mutations in Escherichia coli. 
  • Effective induction of protective systemic immunity with nasally administered vaccines adjuvanted with IL-1. 
  • Efficacy and safety of live attenuated persistent and rapidly cleared Mycobacterium tuberculosis vaccine candidates in non-human primates. 
  • Elicitation of epithelial cell-derived immune effectors by outer membrane vesicles of nontypeable Haemophilus influenzae. 
  • Elucidation of a [4Fe-4S] cluster degradation pathway: rapid kinetic studies of the degradation of Chromatium vinosum HiPIP. 
  • Endotoxin (LPS) stimulates in vitro migration of macrophages from LPS-resistant mice but not from LPS-sensitive mice. 
  • Engineering key components in a synthetic eukaryotic signal transduction pathway. 
  • Engineering prokaryotic channels for control of mammalian tissue excitability. 
  • Engineering the substrate specificity of Staphylococcus aureus Sortase A. The beta6/beta7 loop from SrtB confers NPQTN recognition to SrtA. 
  • Enhanced priming of adaptive immunity by Mycobacterium smegmatis mutants with high-level protein secretion. 
  • Enhancement of macrophage-mediated tumor cell killing by bacterial outer membrane proteins (porins). 
  • Enhancer-origin interaction in plasmid R6K involves a DNA loop mediated by initiator protein. 
  • Enzymatic properties of ALDH1L2, a mitochondrial 10-formyltetrahydrofolate dehydrogenase. 
  • Escherichia coli MoeA and MogA. Function in metal incorporation step of molybdenum cofactor biosynthesis. 
  • Escherichia coli biotin holoenzyme synthetase/bio repressor crystal structure delineates the biotin- and DNA-binding domains. 
  • Escherichia coli mutS-encoded protein binds to mismatched DNA base pairs. 
  • Escherichia coli purine repressor: key residues for the allosteric transition between active and inactive conformations and for interdomain signaling. 
  • Evaluation of the accuracy and reproducibility of a practical PCR panel assay for rapid detection and differentiation of Mycobacterium avium subspecies. 
  • Evidence for genetic drift in endosymbionts (Buchnera): analyses of protein-coding genes. 
  • Evolution of STEC virulence: Insights from the antipredator activities of Shiga toxin producing E. coli. 
  • Evolution of the cytoskeleton. 
  • Examination of type IV pilus expression and pilus-associated phenotypes in Kingella kingae clinical isolates. 
  • Examining relationships between total silver concentration and Sil silver resistance genes in domestic wastewater treatment plants. 
  • Excision and transposition of Tn5 as an SOS activity in Escherichia coli. 
  • Exploitation of macrophages as a replication niche by Legionella pneumophila: response. 
  • Exploiting Pre-Existing CD4+ T Cell Help from Bacille Calmette-Guérin Vaccination to Improve Antiviral Antibody Responses. 
  • Exploring biological electron transfer pathway dynamics with the Pathways plugin for VMD. 
  • Exploring variation in binding of Protein A and Protein G to immunoglobulin type G by isothermal titration calorimetry. 
  • Expression of Kingella kingae type IV pili is regulated by sigma54, PilS, and PilR. 
  • Expression of penicillin G acylase from the cloned pac gene of Escherichia coli ATCC11105. Effects of pacR and temperature. 
  • Expression of photosynthesis genes in relation to nitrogen fixation in the diazotrophic filamentous nonheterocystous cyanobacterium Trichodesmium sp. IMS 101. 
  • Expression of the Pseudomonas syringae avirulence protein AvrB in plant cells alleviates its dependence on the hypersensitive response and pathogenicity (Hrp) secretion system in eliciting genotype-specific hypersensitive cell death. 
  • Expression of the Salmonella spp. virulence factor SifA in yeast alters Rho1 activity on peroxisomes. 
  • Extracellular secretion of pectate lyase by the Erwinia chrysanthemi out pathway is dependent upon Sec-mediated export across the inner membrane. 
  • FabH mutations confer resistance to FabF-directed antibiotics in Staphylococcus aureus. 
  • FbpA--a bacterial transferrin with more to offer. 
  • Fe3+ coordination and redox properties of a bacterial transferrin. 
  • Fecal leukocytes in stool specimens submitted for Clostridium difficile toxin assay. 
  • FimC is a periplasmic PapD-like chaperone that directs assembly of type 1 pili in bacteria. 
  • FimH adhesin of type 1 pili is assembled into a fibrillar tip structure in the Enterobacteriaceae. 
  • Fimbriation of Pseudomonas cepacia. 
  • Flow cytometric analysis of fluorescence resonance energy transfer: a tool for high-throughput screening of molecular interactions in living cells. 
  • Flow linear dichroism and electron microscopic analysis of protein-DNA complexes of a mutant UvrB protein that binds to but cannot kink DNA. 
  • Fluorescence resonance energy transfer analysis of cell surface receptor interactions and signaling using spectral variants of the green fluorescent protein. 
  • Fragment-Based De Novo Design Reveals a Small-Molecule Inhibitor of Helicobacter Pylori HtrA. 
  • Frameshift intermediates in homopolymer runs are removed efficiently by yeast mismatch repair proteins. 
  • Francisella FlmX broadly affects lipopolysaccharide modification and virulence. 
  • From magic spot ppGpp to MESH1: Stringent response from bacteria to metazoa. 
  • FtsZ Constriction Force - Curved Protofilaments Bending Membranes. 
  • FtsZ Protofilament Curvature Is the Opposite of Tubulin Rings. 
  • FtsZ at mid-cell is essential in Escherichia coli until the late stage of constriction. 
  • FtsZ condensates: an in vitro electron microscopy study. 
  • FtsZ filament capping by MciZ, a developmental regulator of bacterial division. 
  • FtsZ filament dynamics at steady state: subunit exchange with and without nucleotide hydrolysis. 
  • FtsZ from Escherichia coli, Azotobacter vinelandii, and Thermotoga maritima--quantitation, GTP hydrolysis, and assembly. 
  • FtsZ from divergent foreign bacteria can function for cell division in Escherichia coli. 
  • FtsZ in bacterial cytokinesis: cytoskeleton and force generator all in one. 
  • FtsZ, a prokaryotic homolog of tubulin? 
  • Functional consequences of substitution mutations in MepR, a repressor of the Staphylococcus aureus MepA multidrug efflux pump gene. 
  • Galectin-3 directs antimicrobial guanylate binding proteins to vacuoles furnished with bacterial secretion systems. 
  • Gateway-compatible tissue-specific vectors for plant transformation. 
  • Gene expression levels influence amino acid usage and evolutionary rates in endosymbiotic bacteria. 
  • Gene product 0.4 increases bacteriophage T7 competitiveness by inhibiting host cell division. 
  • Generation of a Listeria vaccine strain by enhanced caspase-1 activation. 
  • Genetic composition of the Bacillus subtilis SOS system. 
  • Genetic diversity among Mycobacterium avium complex strains recovered from children with and without human immunodeficiency virus infection. 
  • Genome-wide transcriptional analysis of the Arabidopsis thaliana interaction with the plant pathogen Pseudomonas syringae pv. tomato DC3000 and the human pathogen Escherichia coli O157:H7. 
  • Genotypic characteristics of Staphylococcus aureus isolates from a multinational trial of complicated skin and skin structure infections. 
  • GlcNAc-1-P-transferase-tunicamycin complex structure reveals basis for inhibition of N-glycosylation. 
  • Global folds of proteins with low densities of NOEs using residual dipolar couplings: application to the 370-residue maltodextrin-binding protein. 
  • Global gene expression of Prochlorococcus ecotypes in response to changes in nitrogen availability. 
  • Global transcriptional and proteomic analysis of the Sig1 heat shock regulon of Deinococcus radiodurans. 
  • Global whole-cell FTICR mass spectrometric proteomics analysis of the heat shock response in the radioresistant bacterium Deinococcus radiodurans. 
  • Glutamate decreases mitochondrial size and movement in primary forebrain neurons. 
  • Glutathione activates virulence gene expression of an intracellular pathogen. 
  • Growth inhibition of pathogenic bacteria by sulfonylurea herbicides. 
  • HIV-1 neutralization profile and plant-based recombinant expression of actinohivin, an Env glycan-specific lectin devoid of T-cell mitogenic activity. 
  • Harpin, elicitor of the hypersensitive response produced by the plant pathogen Erwinia amylovora. 
  • Helicobacter pylori induces apoptosis of human monocytes but not monocyte-derived dendritic cells: role of the cag pathogenicity island. 
  • Helicobacter pylori stimulates gastric epithelial cell MMP-1 secretion via CagA-dependent and -independent ERK activation. 
  • Hemochromatosis drives acute lethal intestinal responses to hyperyersiniabactin-producing Yersinia pseudotuberculosis. 
  • HexSDF Is Required for Synthesis of a Novel Glycolipid That Mediates Daptomycin and Bacitracin Resistance in C. difficile. 
  • High susceptibility of MDR and XDR Gram-negative pathogens to biphenyl-diacetylene-based difluoromethyl-allo-threonyl-hydroxamate LpxC inhibitors. 
  • High-frequency S-layer protein variation in Campylobacter fetus revealed by sapA mutagenesis. 
  • High-resolution crystal structures of Escherichia coli FtsZ bound to GDP and GTP. 
  • High-resolution solution structure of the beryllofluoride-activated NtrC receiver domain. 
  • Homologs of the vancomycin resistance D-Ala-D-Ala dipeptidase VanX in Streptomyces toyocaensis, Escherichia coli and Synechocystis: attributes of catalytic efficiency, stereoselectivity and regulation with implications for function. 
  • How an enzyme binds the C1 carrier tetrahydromethanopterin. Structure of the tetrahydromethanopterin-dependent formaldehyde-activating enzyme (Fae) from Methylobacterium extorquens AM1. 
  • How bacterial cell division might cheat turgor pressure - a unified mechanism of septal division in Gram-positive and Gram-negative bacteria. 
  • Hrp pilus: an hrp-dependent bacterial surface appendage produced by Pseudomonas syringae pv. tomato DC3000. 
  • Hrp-controlled interkingdom protein transport: learning from flagellar assembly? 
  • HspR is a global negative regulator of heat shock gene expression in Deinococcus radiodurans. 
  • Human IAP-like protein regulates programmed cell death downstream of Bcl-xL and cytochrome c. 
  • Human MutSalpha recognizes damaged DNA base pairs containing O6-methylguanine, O4-methylthymine, or the cisplatin-d(GpG) adduct. 
  • Hydrolytically deficient MutS E694A is defective in the MutL-dependent activation of MutH and in the mismatch-dependent assembly of the MutS.MutL.heteroduplex complex. 
  • Hydroxylated ornithine lipids increase stress tolerance in Rhizobium tropici CIAT899. 
  • Hypervirulent group A Streptococcus emergence in an acaspular background is associated with marked remodeling of the bacterial cell surface. 
  • Identification of BfmR, a response regulator involved in biofilm development, as a target for a 2-Aminoimidazole-based antibiofilm agent. 
  • Identification of Icm protein complexes that play distinct roles in the biogenesis of an organelle permissive for Legionella pneumophila intracellular growth. 
  • Identification of a chimeric emm gene and novel emm pattern in currently circulating strains of emm4 Group A Streptococcus. 
  • Identification of a chloroform-soluble membrane miniprotein in Escherichia coli and its homolog in Salmonella typhimurium. 
  • Identification of a homogentisate-1,2-dioxygenase gene in the fungus Exophiala lecanii-corni: analysis and implications. 
  • Identification of a novel cationic glycolipid in Streptococcus agalactiae that contributes to brain entry and meningitis. 
  • Identification of a putative Salmonella enterica serotype typhimurium host range factor with homology to IpaH and YopM by signature-tagged mutagenesis. 
  • Identification of a regulatory cascade controlling Type III Secretion System 3 gene expression in Burkholderia pseudomallei. 
  • Identification of a two-component fatty acid kinase responsible for host fatty acid incorporation by Staphylococcus aureus. 
  • Identification of an inhibitory circuit that regulates cerebellar Golgi cell activity. 
  • Identification of novel hrp-regulated genes through functional genomic analysis of the Pseudomonas syringae pv. tomato DC3000 genome. 
  • Identification of the Flavobacterium johnsoniae cysteate-fatty acyl transferase required for capnine synthesis and for efficient gliding motility. 
  • Identification of the carotenoid present in the B-800-850 antenna complex from Rhodopseudomonas capsulata as that which responds electrochromically to transmembrane electric fields. 
  • Identification of the second chromophore of Escherichia coli and yeast DNA photolyases as 5,10-methenyltetrahydrofolate. 
  • Identification of two ancillary subunits of Escherichia coli type 1 fimbriae by using antibodies against synthetic oligopeptides of fim gene products. 
  • Identification of undecaprenyl phosphate-beta-D-galactosamine in Francisella novicida and its function in lipid A modification. 
  • Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer. 
  • Immunization with Salmonella enterica serovar Typhimurium-derived outer membrane vesicles delivering the pneumococcal protein PspA confers protection against challenge with Streptococcus pneumoniae. 
  • Immunization with the Haemophilus ducreyi hemoglobin receptor HgbA with adjuvant monophosphoryl lipid A protects swine from a homologous but not a heterologous challenge. 
  • Immunostimulatory membrane proteins potentiate H. pylori-induced carcinogenesis by enabling CagA translocation. 
  • Improved excitation pulse bandwidths using shaped pulses, with application to heteronuclear half filters in macromolecular NMR. 
  • In vitro assembly and GTP hydrolysis by bacterial tubulins BtubA and BtubB. 
  • In vitro assembly studies of FtsZ/tubulin-like proteins (TubZ) from Bacillus plasmids: evidence for a capping mechanism. 
  • In vitro synthesis of molybdopterin from precursor Z using purified converting factor. Role of protein-bound sulfur in formation of the dithiolene. 
  • In vivo characterization of Escherichia coli ftsZ mutants: effects on Z-ring structure and function. 
  • In vivo post-translational processing and subunit reconstitution of cephalosporin acylase from Pseudomonas sp. 130. 
  • In vivo requirement for RecJ, ExoVII, ExoI, and ExoX in methyl-directed mismatch repair. 
  • In-vivo studies on the cis-acting replication initiator protein of IncFII plasmid NR1. 
  • Incorporation of extracellular fatty acids by a fatty acid kinase-dependent pathway in Staphylococcus aureus. 
  • Inducing circular RNA formation using the CRISPR endoribonuclease Csy4. 
  • Induction of mitogenic signalling in the 1LN prostate cell line on exposure to submicromolar concentrations of cadmium+. 
  • Influence of berberine sulfate on synthesis and expression of Pap fimbrial adhesin in uropathogenic Escherichia coli. 
  • Informing Antibiotic Treatment Decisions: Evaluating Rapid Molecular Diagnostics To Identify Susceptibility and Resistance to Carbapenems against Acinetobacter spp. in PRIMERS III. 
  • Inhibition of Methicillin-resistant Staphylococcus aureus-induced cytokines mRNA production in human bone marrow derived mesenchymal stem cells by 1,25-dihydroxyvitamin D3. 
  • Inhibition of the Staphylococcus aureus sortase transpeptidase SrtA by phosphinic peptidomimetics. 
  • Initiation of methyl-directed mismatch repair. 
  • Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome. 
  • Innate immunity in plants: an arms race between pattern recognition receptors in plants and effectors in microbial pathogens. 
  • Inside-out Z rings--constriction with and without GTP hydrolysis. 
  • Insight into F plasmid DNA segregation revealed by structures of SopB and SopB-DNA complexes. 
  • Insights into the Autoproteolytic Processing and Catalytic Mechanism of the Chlamydia trachomatis Virulence-Associated Protease CPAF. 
  • Insights into the nature of DNA binding of AbrB-like transcription factors. 
  • Integration of the Salmonella Typhimurium Methylome and Transcriptome Reveals That DNA Methylation and Transcriptional Regulation Are Largely Decoupled under Virulence-Related Conditions. 
  • Integration specificities of two lambdoid phages (21 and e14) that insert at the same attB site. 
  • Intranasal vaccination with the recombinant Listeria monocytogenes ΔactA prfA* mutant elicits robust systemic and pulmonary cellular responses and secretory mucosal IgA. 
  • InvB is a type III secretion chaperone specific for SspA. 
  • Invasive disease caused by nontuberculous mycobacteria, Tanzania. 
  • Investigation of the role of electrostatic charge in activation of the Escherichia coli response regulator CheY. 
  • Involvement of the S-layer proteins Hpi and SlpA in the maintenance of cell envelope integrity in Deinococcus radiodurans R1. 
  • Involvement of two putative alternative sigma factors in stress response of the radioresistant bacterium Deinococcus radiodurans. 
  • Ion channels: an open and shut case. 
  • Isolation and characterization of the Escherichia coli mutH gene product. 
  • Isolation and characterization of the Escherichia coli mutL gene product. 
  • Isolation and characterization of the replicon of a Thiobacillus intermedius plasmid. 
  • Isolation and characterization of two European strains of Ehrlichia phagocytophila of equine origin. 
  • Isolation of MutSbeta from human cells and comparison of the mismatch repair specificities of MutSbeta and MutSalpha. 
  • Isolation of a new RNA polymerase-binding protein from sporulating Bacillus subtilis. 
  • Isolation, structure and biological activities of platensimycin B4 from Streptomyces platensis. 
  • Kinetic analysis of the zinc-dependent deacetylase in the lipid A biosynthetic pathway. 
  • Kinetic characterization of Salmonella FliK-FlhB interactions demonstrates complexity of the Type III secretion substrate-specificity switch. 
  • Kinetic studies of tryptophan synthetase. Interaction of L-serine, indole, and tryptophan with the native enzyme. 
  • Kinetics and mechanism of exogenous anion exchange in FeFbpA-NTA: significance of periplasmic anion lability and anion binding activity of ferric binding protein A. 
  • Kinetics and mechanism of iron(III) complexation by ferric binding protein: the role of phosphate. 
  • Kinetics of iron release from ferric binding protein (FbpA): mechanistic implications in bacterial periplasm-to-cytosol Fe3+ transport. 
  • Kingella kingae expresses type IV pili that mediate adherence to respiratory epithelial and synovial cells. 
  • Lactobacillus reuteri DSM 20016 produces cobalamin-dependent diol dehydratase in metabolosomes and metabolizes 1,2-propanediol by disproportionation. 
  • Lambda transducing phages for the nalA gene of Escherichia coli and conditional lethal nalA mutations. 
  • Large-scale death of retinal astrocytes during normal development is non-apoptotic and implemented by microglia. 
  • Lateral density of receptor arrays in the membrane plane influences sensitivity of the E. coli chemotaxis response. 
  • LexA protein of Escherichia coli represses expression of the Tn5 transposase gene. 
  • Lipid A Has Significance for Optimal Growth of Coxiella burnetii in Macrophage-Like THP-1 Cells and to a Lesser Extent in Axenic Media and Non-phagocytic Cells. 
  • Lipooligosaccharide is required for the generation of infectious elementary bodies in Chlamydia trachomatis. 
  • Liposome division by a simple bacterial division machinery. 
  • Liposome reconstitution and transport assay for recombinant transporters. 
  • Long range dynamic effects of point-mutations trap a response regulator in an active conformation. 
  • Longitudinal characterization of synovial fluid biomarkers in the canine meniscectomy model of osteoarthritis. 
  • Low-shear modeled microgravity: a global environmental regulatory signal affecting bacterial gene expression, physiology, and pathogenesis. 
  • Macromolecular assembly of the transition state regulator AbrB in its unbound and complexed states probed by microelectrospray ionization mass spectrometry. 
  • Mast cell activation by Mycobacterium tuberculosis: mediator release and role of CD48. 
  • Mast cell degranulation induced by type 1 fimbriated Escherichia coli in mice. 
  • Mast cell phagocytosis of FimH-expressing enterobacteria. 
  • Mechanism of 5'-directed excision in human mismatch repair. 
  • Mechanism of action of nalidixic acid: purification of Escherichia coli nalA gene product and its relationship to DNA gyrase and a novel nicking-closing enzyme. 
  • Mechanism of corepressor-mediated specific DNA binding by the purine repressor. 
  • Mechanism of staphylococcal multiresistance plasmid replication origin assembly by the RepA protein. 
  • Mechanism of ubiquitin activation revealed by the structure of a bacterial MoeB-MoaD complex. 
  • Mechanisms of tolerance induced by an immunotoxin against CD3 epsilon in a rhesus kidney allograft model. 
  • Mechanistic study on the reaction of a radical SAM dehydrogenase BtrN by electron paramagnetic resonance spectroscopy. 
  • Membrane disruption by antimicrobial fatty acids releases low-molecular-weight proteins from Staphylococcus aureus. 
  • MetJ repressor interactions with DNA probed by in-cell NMR. 
  • Methyl-directed DNA mismatch repair in Escherichia coli. 
  • Methyl-directed mismatch repair is bidirectional. 
  • Methylation of the FSHD syndrome-linked subtelomeric repeat in normal and FSHD cell cultures and tissues. 
  • Methylthioadenosine Suppresses Salmonella Virulence. 
  • Microbiological and genotypic analysis of methicillin-resistant Staphylococcus aureus bacteremia. 
  • Minimal determinants for binding activated G alpha from the structure of a G alpha(i1)-peptide dimer. 
  • Mismatch repair proteins MutS and MutL inhibit RecA-catalyzed strand transfer between diverged DNAs. 
  • Mismatch repair proteins and mitotic genome stability. 
  • Mismatch-, MutS-, MutL-, and helicase II-dependent unwinding from the single-strand break of an incised heteroduplex. 
  • Mismatch-containing oligonucleotide duplexes bound by the E. coli mutS-encoded protein. 
  • Modeling the physics of FtsZ assembly and force generation. 
  • Modulation of MutS ATP hydrolysis by DNA cofactors. 
  • Modulation of the binding of signal peptides to lipid bilayers by dipoles near the hydrocarbon-water interface. 
  • Molecular Analysis of pSK1 par: A Novel Plasmid Partitioning System Encoded by Staphylococcal Multiresistance Plasmids. 
  • Molecular basis of ChvE function in sugar binding, sugar utilization, and virulence in Agrobacterium tumefaciens. 
  • Molecular characterization of group A Streptococcus maltodextrin catabolism and its role in pharyngitis. 
  • Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria. 
  • Molecular insights into DNA binding and anchoring by the Bacillus subtilis sporulation kinetochore-like RacA protein. 
  • Molecular mechanism by which the nucleoid occlusion factor, SlmA, keeps cytokinesis in check. 
  • Molecular structure and function of the novel BrnT/BrnA toxin-antitoxin system of Brucella abortus. 
  • Molecular taxonomy of major neuronal classes in the adult mouse forebrain. 
  • Molybdenum threshold for ecosystem scale alternative vanadium nitrogenase activity in boreal forests. 
  • Multicenter study to determine disk diffusion and broth microdilution criteria for prediction of high- and low-level mupirocin resistance in Staphylococcus aureus. 
  • Multicentre surveillance of the prevalence and molecular epidemiology of macrolide resistance among pharyngeal isolates of group A streptococci in the USA. 
  • Multidrug-binding transcription factor QacR binds the bivalent aromatic diamidines DB75 and DB359 in multiple positions. 
  • Multifactorial determinants of protein expression in prokaryotic open reading frames. 
  • Multiple activities of the plant pathogen type III effector proteins WtsE and AvrE require WxxxE motifs. 
  • MutL traps MutS at a DNA mismatch. 
  • MutS and MutL activate DNA helicase II in a mismatch-dependent manner. 
  • MutS mediates heteroduplex loop formation by a translocation mechanism. 
  • Mutagenesis studies of substrate recognition and catalysis in the sortase A transpeptidase from Staphylococcus aureus. 
  • Mutants of FtsZ targeting the protofilament interface: effects on cell division and GTPase activity. 
  • Mutation detection with MutH, MutL, and MutS mismatch repair proteins. 
  • Mutational analysis of active site residues in the Staphylococcus aureus transpeptidase SrtA. 
  • Mutational analysis of potential zinc-binding residues in the active site of the enterococcal D-Ala-D-Ala dipeptidase VanX. 
  • Mutations in hemG mediate resistance to salicylidene acylhydrazides, demonstrating a novel link between protoporphyrinogen oxidase (HemG) and Chlamydia trachomatis infectivity. 
  • NAIP inflammasomes give the NOD to bacterial ligands. 
  • NMR and XAS reveal an inner-sphere metal binding site in the P4 helix of the metallo-ribozyme ribonuclease P. 
  • NMR assignment of the N-terminal repeat domain of Bacillus subtilis ClpC. 
  • NMR solution structure and DNA-binding model of the DNA-binding domain of competence protein A. 
  • NMR structure of AbhN and comparison with AbrBN: FIRST insights into the DNA binding promiscuity and specificity of AbrB-like transition state regulator proteins. 
  • NMR structure of activated CheY. 
  • Necroptosis of infiltrated macrophages drives Yersinia pestis dispersal within buboes. 
  • Negative-stain electron microscopy of inside-out FtsZ rings reconstituted on artificial membrane tubules show ribbons of protofilaments. 
  • Neighborhood socio-economic characteristics, African ancestry, and Helicobacter pylori sero-prevalence. 
  • Neisseria gonorrhoeae FitA interacts with FitB to bind DNA through its ribbon-helix-helix motif. 
  • Neutrophil activation by nascent FimH subunits of type 1 fimbriae purified from the periplasm of Escherichia coli. 
  • New lessons in the regulation of glucose metabolism taught by the glucose 6-phosphatase system. 
  • Niche-specific contribution to streptococcal virulence of a MalR-regulated carbohydrate binding protein. 
  • Nine enzymes are required for assembly of the pacidamycin group of peptidyl nucleoside antibiotics. 
  • Nonfunctional Missense Mutants in Two Well Characterized Cytosolic Enzymes Reveal Important Information About Protein Structure and Function. 
  • Nucleotide sequence of a gene cluster involved in entry of E colicins and single-stranded DNA of infecting filamentous bacteriophages into Escherichia coli. 
  • Optimized production and analysis of the staphylococcal multidrug efflux protein QacA. 
  • Optogenetic manipulation and photoacoustic imaging using a near-infrared transgenic mouse model. 
  • Order out of disorder: working cycle of an intrinsically unfolded chaperone. 
  • Organization of carboxysome genes in the thiobacilli. 
  • Orientation of LamB signal peptides in bilayers: influence of lipid probes on peptide binding and interpretation of fluorescence quenching data. 
  • Osmolyte-induced folding of an intrinsically disordered protein: folding mechanism in the absence of ligand. 
  • Outcomes of transplantation using organs from a donor infected with Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae. 
  • Outer Membrane Vesiculation Facilitates Surface Exchange and In Vivo Adaptation of Vibrio cholerae. 
  • P1 partition complex assembly involves several modes of protein-DNA recognition. 
  • PDAPP; YFP double transgenic mice: a tool to study amyloid-beta associated changes in axonal, dendritic, and synaptic structures. 
  • Pathogen virulence factors as molecular probes of basic plant cellular functions. 
  • Pathogenic Bacteria Target Plant Plasmodesmata to Colonize and Invade Surrounding Tissues. 
  • Performance of Homologous and Heterologous Prime-Boost Immunization Regimens of Recombinant Adenovirus and Modified Vaccinia Virus Ankara Expressing an Ag85B-TB10.4 Fusion Protein against Mycobacterium tuberculosis. 
  • Performance of multiplex serology in discriminating active vs past Helicobacter pylori infection in a primarily African American population in the southeastern United States. 
  • Peroxisome function regulates growth on glucose in the basidiomycete fungus Cryptococcus neoformans. 
  • Persistent bacteremia due to methicillin-resistant Staphylococcus aureus infection is associated with agr dysfunction and low-level in vitro resistance to thrombin-induced platelet microbicidal protein. 
  • Perturbation of Staphylococcus aureus gene expression by the enoyl-acyl carrier protein reductase inhibitor AFN-1252. 
  • Phosphoprotein Crh-Ser46-P displays altered binding to CcpA to effect carbon catabolite regulation. 
  • Phosphorus-based SAHA analogues as histone deacetylase inhibitors. 
  • Phosphorylation of the group A Streptococcal CovR response regulator causes dimerization and promoter-specific recruitment by RNA polymerase. 
  • Phylogeny of Wolbachia pipientis based on gltA, groEL and ftsZ gene sequences: clustering of arthropod and nematode symbionts in the F supergroup, and evidence for further diversity in the Wolbachia tree. 
  • Plakoglobin and High-Mobility Group Box 1 Mediate Intestinal Epithelial Cell Apoptosis Induced by Clostridioides difficile TcdB. 
  • Plasmid protein TubR uses a distinct mode of HTH-DNA binding and recruits the prokaryotic tubulin homolog TubZ to effect DNA partition. 
  • Pleiotropic alterations in lipid metabolism in yeast sac1 mutants: relationship to "bypass Sec14p" and inositol auxotrophy. 
  • Polarized secretion. 
  • Polymer Nanodiscs: Discoidal Amphiphilic Block Copolymer Membranes as a New Platform for Membrane Proteins. 
  • Polymerization of Ftsz, a bacterial homolog of tubulin. is assembly cooperative? 
  • Powerful screens for bacterial virulence proteins. 
  • Prediagnostic Antibody Responses to Fusobacterium nucleatum Proteins Are Not Associated with Risk of Colorectal Cancer in a Large U.S. Consortium. 
  • Predominantly buried residues in the response regulator Spo0F influence specific sensor kinase recognition. 
  • Preliminary structural studies on the multi-ligand-binding domain of the transcription activator, BmrR, from Bacillus subtilis. 
  • Prevalence of Candida auris in Canadian acute care hospitals among at-risk patients, 2018. 
  • Probing for Binding Regions of the FtsZ Protein Surface through Site-Directed Insertions: Discovery of Fully Functional FtsZ-Fluorescent Proteins. 
  • Probing of the cis-5-phenyl proline scaffold as a platform for the synthesis of mechanism-based inhibitors of the Staphylococcus aureus sortase SrtA isoform. 
  • Probing the domain structure of FtsZ by random truncation and insertion of GFP. 
  • Prochlorococcus: approved for export. 
  • Prokaryotic transcription regulators: more than just the helix-turn-helix motif. 
  • Promoter recognition by a complex of Spx and the C-terminal domain of the RNA polymerase alpha subunit. 
  • Protease-cleaved iron-transferrin augments oxidant-mediated endothelial cell injury via hydroxyl radical formation. 
  • Protein electron transfer rates set by the bridging secondary and tertiary structure. 
  • Protein fabrication automation. 
  • Protein kinase A operates a molecular switch that governs yeast pseudohyphal differentiation. 
  • Protein kinetics: structures of intermediates and reaction mechanism from time-resolved x-ray data. 
  • Protein loop closure using orientational restraints from NMR data. 
  • Protein nanotechnology: the new frontier in biosciences. 
  • Proteomic Profiling Reveals Distinct Bacterial Extracellular Vesicle Subpopulations with Possibly Unique Functionality. 
  • Proteomic analysis of an unculturable bacterial endosymbiont (Blochmannia) reveals high abundance of chaperonins and biosynthetic enzymes. 
  • Protofilaments and rings, two conformations of the tubulin family conserved from bacterial FtsZ to alpha/beta and gamma tubulin. 
  • Pseudomonas syringae Effector Avirulence Protein E Localizes to the Host Plasma Membrane and Down-Regulates the Expression of the NONRACE-SPECIFIC DISEASE RESISTANCE1/HARPIN-INDUCED1-LIKE13 Gene Required for Antibacterial Immunity in Arabidopsis. 
  • Pseudomonas syringae pv. tomato DC3000 HopPtoM (CEL ORF3) is important for lesion formation but not growth in tomato and is secreted and translocated by the Hrp type III secretion system in a chaperone-dependent manner. 
  • Pseudomonas syringae pv. tomato DC3000: a model pathogen for probing disease susceptibility and hormone signaling in plants. 
  • Pulmonary immune-compartment-specific interferon gamma responses in HIV-infected individuals with active tuberculosis (TB) in an area of high TB prevalence. 
  • Purification and assembly of FtsZ. 
  • QacR-cation recognition is mediated by a redundancy of residues capable of charge neutralization. 
  • Quantitative immunoassay of anti-La antibodies using purified recombinant La antigen. 
  • Quantitative proteomics reveals metabolic and pathogenic properties of Chlamydia trachomatis developmental forms. 
  • Quenching of DNA cross-link precursors of chloroethylnitrosoureas and attenuation of DNA interstrand cross-linking by glutathione. 
  • Quorum-sensing regulation of a copper toxicity system in Pseudomonas aeruginosa. 
  • RNA-guided transcriptional silencing in vivo with S. aureus CRISPR-Cas9 repressors. 
  • Rapid assembly dynamics of the Escherichia coli FtsZ-ring demonstrated by fluorescence recovery after photobleaching. 
  • Rapid dendritic transport of TGN38, a putative cargo receptor. 
  • Rapid determination of protein folds using residual dipolar couplings. 
  • Rapid in vitro assembly of Caulobacter crescentus FtsZ protein at pH 6.5 and 7.2. 
  • Rapid molecular detection of tuberculosis and rifampin resistance. 
  • Re-design of Rhodobacter sphaeroides dimethyl sulfoxide reductase. Enhancement of adenosine N1-oxide reductase activity. 
  • Reassessing the role of the secreted protease CPAF in Chlamydia trachomatis infection through genetic approaches. 
  • Receptor-associated protein binding blocks ubiquitinylation of the low density lipoprotein receptor-related protein. 
  • Recognition of multiple drugs by a single protein: a trivial solution of an old paradox. 
  • Recombinant Rhodobacter capsulatus xanthine dehydrogenase, a useful model system for the characterization of protein variants leading to xanthinuria I in humans. 
  • Reconstitution of contractile FtsZ rings in liposomes. 
  • Reconstitution of protein translocation from detergent-solubilized Escherichia coli inverted vesicles: PrlA protein-deficient vesicles efficiently translocate precursor proteins. 
  • Reduced Chlorhexidine and Daptomycin Susceptibility in Vancomycin-Resistant Enterococcus faecium after Serial Chlorhexidine Exposure. 
  • Reduced susceptibility of Staphylococcus aureus to vancomycin and platelet microbicidal protein correlates with defective autolysis and loss of accessory gene regulator (agr) function. 
  • Redundant exonuclease involvement in Escherichia coli methyl-directed mismatch repair. 
  • Regeneration Genetics. 
  • Regulation of iron transport related genes by boron in the marine bacterium Marinobacter algicola DG893. 
  • Regulation of ribosomal protein synthesis in an Escherichia coli mutant missing ribosomal protein L1. 
  • Regulation of streptokinase expression by CovR/S in Streptococcus pyogenes: CovR acts through a single high-affinity binding site. 
  • Regulation of the transcriptional activator NtrC1: structural studies of the regulatory and AAA+ ATPase domains. 
  • Relative gene expression quantification in a fungal gas-phase biofilter. 
  • Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs. 
  • Reversal of acute allograft rejection using immunotoxin. 
  • Revised structure of the AbrB N-terminal domain unifies a diverse superfamily of putative DNA-binding proteins. 
  • Risk factors for and estimated incidence of community-associated Clostridium difficile infection, North Carolina, USA. 
  • Role of Pseudomonas aeruginosa dinB-encoded DNA polymerase IV in mutagenesis. 
  • Role of residue 147 in the gene regulatory function of the Escherichia coli purine repressor. 
  • Role of the Hrp pilus in type III protein secretion in Pseudomonas syringae. 
  • Salmonella Activation of STAT3 Signaling by SarA Effector Promotes Intracellular Replication and Production of IL-10. 
  • Salmonella effectors translocated across the vacuolar membrane interact with the actin cytoskeleton. 
  • Salmonella typhimurium impedes innate immunity with a mast-cell-suppressing protein tyrosine phosphatase, SptP. 
  • Salmonella typhimurium leucine-rich repeat proteins are targeted to the SPI1 and SPI2 type III secretion systems. 
  • Segrosome structure revealed by a complex of ParR with centromere DNA. 
  • Selection of strains for quality assessment of the disk induction method for detection of inducible clindamycin resistance in Staphylococci: a CLSI collaborative study. 
  • Sequence context of indel mutations and their effect on protein evolution in a bacterial endosymbiont. 
  • Sequestration of a dual function DNA-binding protein by Vibrio cholerae CRP. 
  • Serologic Response to Helicobacter pylori Proteins Associated With Risk of Colorectal Cancer Among Diverse Populations in the United States. 
  • Shift in S-layer protein expression responsible for antigenic variation in Campylobacter fetus. 
  • Signal discrimination by differential regulation of protein stability in quorum sensing. 
  • Signatures of protein-DNA recognition in free DNA binding sites. 
  • Sinorhizobium meliloti phospholipase C required for lipid remodeling during phosphorus limitation. 
  • Site-directed mutagenesis studies of the high-affinity streptavidin-biotin complex: contributions of tryptophan residues 79, 108, and 120. 
  • SlmA forms a higher-order structure on DNA that inhibits cytokinetic Z-ring formation over the nucleoid. 
  • Small near-infrared photochromic protein for photoacoustic multi-contrast imaging and detection of protein interactions in vivo. 
  • Solubilization of tricalcium phosphate by P(3HB) accumulating Azotobacter chroococcum MAL-201. 
  • Solution structure and function of YndB, an AHSA1 protein from Bacillus subtilis. 
  • Sortase ligation enables homogeneous GPCR phosphorylation to reveal diversity in β-arrestin coupling. 
  • Sortase transpeptidases: insights into mechanism, substrate specificity, and inhibition. 
  • Sortase-catalyzed initiator attachment enables high yield growth of a stealth polymer from the C terminus of a protein. 
  • Specificity of the type II secretion systems of enterotoxigenic Escherichia coli and Vibrio cholerae for heat-labile enterotoxin and cholera toxin. 
  • Split tolerance induced by immunotoxin in a rhesus kidney allograft model. 
  • Staphylococcus aureus evades lysozyme-based peptidoglycan digestion that links phagocytosis, inflammasome activation, and IL-1beta secretion. 
  • Staphylococcus aureus sortase A contributes to the Trojan horse mechanism of immune defense evasion with its intrinsic resistance to Cys184 oxidation. 
  • Staphylococcus aureus sortase transpeptidase SrtA: insight into the kinetic mechanism and evidence for a reverse protonation catalytic mechanism. 
  • Statistical analysis of genetic interactions in Tn-Seq data. 
  • Stoichiometries of protein-protein/DNA binding and conformational changes for the transition-state regulator AbrB measured by pseudo cell-size exclusion chromatography-mass spectrometry. 
  • Stomatal Defense a Decade Later. 
  • Straight and curved conformations of FtsZ are regulated by GTP hydrolysis. 
  • Stress-induced outer membrane vesicle production by Pseudomonas aeruginosa. 
  • Structural analysis of semi-specific oligosaccharide recognition by a cellulose-binding protein of thermotoga maritima reveals adaptations for functional diversification of the oligopeptide periplasmic binding protein fold. 
  • Structural analysis of the purine repressor, an Escherichia coli DNA-binding protein. 
  • Structural and Biochemical Characterization of the Francisella tularensis Pathogenicity Regulator, Macrophage Locus Protein A (MglA). 
  • Structural and Functional Analyses Reveal Insights into the Molecular Properties of the Escherichia coli Z Ring Stabilizing Protein, ZapC. 
  • Structural and Functional Characterization of Sulfonium Carbon-Oxygen Hydrogen Bonding in the Deoxyamino Sugar Methyltransferase TylM1. 
  • Structural and biochemical characterization of MepR, a multidrug binding transcription regulator of the Staphylococcus aureus multidrug efflux pump MepA. 
  • Structural basis for allosteric control of the transcription regulator CcpA by the phosphoprotein HPr-Ser46-P. 
  • Structural basis for cooperative DNA binding by two dimers of the multidrug-binding protein QacR. 
  • Structural basis for the metal-selective activation of the manganese transport regulator of Bacillus subtilis. 
  • Structural basis of multidrug recognition by BmrR, a transcription activator of a multidrug transporter. 
  • Structural basis of multifunctional bovine mitochondrial cytochrome bc1 complex. 
  • Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters. 
  • Structural basis of pilus subunit recognition by the PapD chaperone. 
  • Structural basis of selection and thermostability of laboratory evolved Bacillus subtilis lipase. 
  • Structural basis of the UDP-diacylglucosamine pyrophosphohydrolase LpxH inhibition by sulfonyl piperazine antibiotics. 
  • Structural biology of bacterial multidrug resistance gene regulators. 
  • Structural biology of plasmid partition: uncovering the molecular mechanisms of DNA segregation. 
  • Structural biology of plasmid segregation proteins. 
  • Structural comparison of the free and DNA-bound forms of the purine repressor DNA-binding domain. 
  • Structural determinants for signal sequence function in the mammalian endoplasmic reticulum. 
  • Structural evidence that the P/Q domain of ZipA is an unstructured, flexible tether between the membrane and the C-terminal FtsZ-binding domain. 
  • Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides. 
  • Structural genomics of Pyrococcus furiosus: X-ray crystallography reveals 3D domain swapping in rubrerythrin. 
  • Structural insights into inhibition of lipid I production in bacterial cell wall synthesis. 
  • Structural mechanism for the fine-tuning of CcpA function by the small molecule effectors glucose 6-phosphate and fructose 1,6-bisphosphate. 
  • Structural mechanism of ATP-induced polymerization of the partition factor ParF: implications for DNA segregation. 
  • Structural mechanism of organic hydroperoxide induction of the transcription regulator OhrR. 
  • Structural mechanism of the simultaneous binding of two drugs to a multidrug-binding protein. 
  • Structural mechanism of transcription regulation of the Staphylococcus aureus multidrug efflux operon mepRA by the MarR family repressor MepR. 
  • Structural mechanisms of QacR induction and multidrug recognition. 
  • Structural, Biochemical, and In Vivo Characterization of MtrR-Mediated Resistance to Innate Antimicrobials by the Human Pathogen Neisseria gonorrhoeae. 
  • Structure and DNA-binding traits of the transition state regulator AbrB. 
  • Structure and filament dynamics of the pSK41 actin-like ParM protein: implications for plasmid DNA segregation. 
  • Structure and function of the UvrB protein. 
  • Structure and functional properties of the Bacillus subtilis transcriptional repressor Rex. 
  • Structure of FitAB from Neisseria gonorrhoeae bound to DNA reveals a tetramer of toxin-antitoxin heterodimers containing pin domains and ribbon-helix-helix motifs. 
  • Structure of a four-way bridged ParB-DNA complex provides insight into P1 segrosome assembly. 
  • Structure of a trimeric bacterial microcompartment shell protein, EtuB, associated with ethanol utilization in Clostridium kluyveri. 
  • Structure of an OhrR-ohrA operator complex reveals the DNA binding mechanism of the MarR family. 
  • Structure of the Francisella response regulator QseB receiver domain, and characterization of QseB inhibition by antibiofilm 2-aminoimidazole-based compounds. 
  • Structure of the Z Ring-associated Protein, ZapD, Bound to the C-terminal Domain of the Tubulin-like Protein, FtsZ, Suggests Mechanism of Z Ring Stabilization through FtsZ Cross-linking. 
  • Structure of the deacetylase LpxC bound to the antibiotic CHIR-090: Time-dependent inhibition and specificity in ligand binding. 
  • Structure of the manganese-bound manganese transport regulator of Bacillus subtilis. 
  • Structure, inhibition, and regulation of essential lipid A enzymes. 
  • Structure-Activity Relationship of Sulfonyl Piperazine LpxH Inhibitors Analyzed by an LpxE-Coupled Malachite Green Assay. 
  • Structure-based design of robust glucose biosensors using a Thermotoga maritima periplasmic glucose-binding protein. 
  • Structure-based redesign of corepressor specificity of the Escherichia coli purine repressor by substitution of residue 190. 
  • Structures of Bacterial MraY and Human GPT Provide Insights into Rational Antibiotic Design. 
  • Structures of BmrR-drug complexes reveal a rigid multidrug binding pocket and transcription activation through tyrosine expulsion. 
  • Structures of Neisseria gonorrhoeae MtrR-operator complexes reveal molecular mechanisms of DNA recognition and antibiotic resistance-conferring clinical mutations. 
  • Structures of carbon catabolite protein A-(HPr-Ser46-P) bound to diverse catabolite response element sites reveal the basis for high-affinity binding to degenerate DNA operators. 
  • Structures of maintenance of carboxysome distribution Walker-box McdA and McdB adaptor homologs. 
  • Structures of partition protein ParA with nonspecific DNA and ParB effector reveal molecular insights into principles governing Walker-box DNA segregation. 
  • Structures of regulatory machinery reveal novel molecular mechanisms controlling B. subtilis nitrogen homeostasis. 
  • Structures of the activator of K. pneumonia biofilm formation, MrkH, indicates PilZ domains involved in c-di-GMP and DNA binding. 
  • Structures of the nucleoid occlusion protein SlmA bound to DNA and the C-terminal domain of the cytoskeletal protein FtsZ. 
  • Structures of three polycystic kidney disease-like domains from Clostridium histolyticum collagenases ColG and ColH. 
  • Studies on the biosynthesis of the lipodepsipeptide antibiotic Ramoplanin A2. 
  • Subcellular Localization of Pseudomonas syringae pv. tomato Effector Proteins in Plants. 
  • Subcellular localization and functional analysis of the Arabidopsis GTPase RabE. 
  • Subspecific differentiation of Mycobacterium avium complex strains by automated sequencing of a region of the gene (hsp65) encoding a 65-kilodalton heat shock protein. 
  • Substrate recognition by the EcoRI endonuclease. 
  • SulA inhibits assembly of FtsZ by a simple sequestration mechanism. 
  • Suppression of the microRNA pathway by bacterial effector proteins. 
  • Suprastructures and dynamic properties of Mycobacterium tuberculosis FtsZ. 
  • SymROP: ROP protein with identical helices redesigned by all-atom contact analysis and molecular dynamics. 
  • Synthesis and evaluation of cyclopentane-based muraymycin analogs targeting MraY. 
  • Synthesis and preliminary biological evaluation of (3-iodobenzoyl)norbiotinamide and ((5-iodo-3-pyridinyl)carbonyl)norbiotinamide: two radioiodinated biotin conjugates with improved stability. 
  • Synthesis of empty bacterial microcompartments, directed organelle protein incorporation, and evidence of filament-associated organelle movement. 
  • Synthesis of macrocyclic nucleoside antibacterials and their interactions with MraY. 
  • T7-induced DNA polymerase. Requirement for thioredoxin sulfhydryl groups. 
  • Tandem mass spectrometry acquisition approaches to enhance identification of protein-protein interactions using low-energy collision-induced dissociative chemical crosslinking reagents. 
  • Targeting cells with single vectors using multiple-feature Boolean logic. 
  • Tetrameric c-di-GMP mediates effective transcription factor dimerization to control Streptomyces development. 
  • The 3.7 A projection map of the glycerol facilitator GlpF: a variant of the aquaporin tetramer. 
  • The C-terminal linker of Escherichia coli FtsZ functions as an intrinsically disordered peptide. 
  • The Chlamydia protease CPAF regulates host and bacterial proteins to maintain pathogen vacuole integrity and promote virulence. 
  • The Chlamydia trachomatis Inclusion Membrane Protein CpoS Counteracts STING-Mediated Cellular Surveillance and Suicide Programs. 
  • The Chlamydia trachomatis Protease CPAF Contains a Cryptic PDZ-Like Domain with Similarity to Human Cell Polarity and Tight Junction PDZ-Containing Proteins. 
  • The Chloroplast Tubulin Homologs FtsZA and FtsZB from the Red Alga Galdieria sulphuraria Co-assemble into Dynamic Filaments. 
  • The Closing Mechanism of DNA Polymerase I at Atomic Resolution. 
  • The CovR response regulator of group A streptococcus (GAS) acts directly to repress its own promoter. 
  • The Drosophila claret segregation protein is a minus-end directed motor molecule. 
  • The Early-Acting Peroxin PEX19 Is Redundantly Encoded, Farnesylated, and Essential for Viability in Arabidopsis thaliana. 
  • The Erwinia amylovora avrRpt2EA gene contributes to virulence on pear and AvrRpt2EA is recognized by Arabidopsis RPS2 when expressed in pseudomonas syringae. 
  • The FtsZ protofilament and attachment of ZipA--structural constraints on the FtsZ power stroke. 
  • The GBP1 microcapsule interferes with IcsA-dependent septin cage assembly around Shigella flexneri. 
  • The GO system prevents ROS-induced mutagenesis and killing in Pseudomonas aeruginosa. 
  • The Haemophilus influenzae hFbpABC Fe3+ transporter: analysis of the membrane permease and development of a gallium-based screen for mutants. 
  • The Hrp pilus: learning from flagella. 
  • The Lipid A 1-Phosphatase, LpxE, Functionally Connects Multiple Layers of Bacterial Envelope Biogenesis. 
  • The MerR-like protein BldC binds DNA direct repeats as cooperative multimers to regulate Streptomyces development. 
  • The MetJ regulon in gammaproteobacteria determined by comparative genomics methods. 
  • The MotA transcriptional activator of bacteriophage T4 binds to its specific DNA site as a monomer. 
  • The MutL ATPase is required for mismatch repair. 
  • The Mycobacterium tuberculosis 71-kDa heat-shock protein induces proliferation and cytokine secretion by murine gut intraepithelial lymphocytes. 
  • The NMR solution structure of BeF(3)(-)-activated Spo0F reveals the conformational switch in a phosphorelay system. 
  • The Pseudomonas syringae Hrp regulation and secretion system controls the production and secretion of multiple extracellular proteins. 
  • The Pseudomonas syringae Type III Effector HopG1 Induces Actin Remodeling to Promote Symptom Development and Susceptibility during Infection. 
  • The Pseudomonas syringae type III effector tyrosine phosphatase HopAO1 suppresses innate immunity in Arabidopsis thaliana. 
  • The Salmonella Secreted Effector SarA/SteE Mimics Cytokine Receptor Signaling to Activate STAT3. 
  • The Solution Structures and Interaction of SinR and SinI: Elucidating the Mechanism of Action of the Master Regulator Switch for Biofilm Formation in Bacillus subtilis. 
  • The Staphylococcus aureus pSK41 plasmid-encoded ArtA protein is a master regulator of plasmid transmission genes and contains a RHH motif used in alternate DNA-binding modes. 
  • The Streptomyces master regulator BldD binds c-di-GMP sequentially to create a functional BldD2-(c-di-GMP)4 complex. 
  • The Structure of the Biofilm-controlling Response Regulator BfmR from Acinetobacter baumannii Reveals Details of Its DNA-binding Mechanism. 
  • The TetR family of transcriptional repressors. 
  • The UDP-diacylglucosamine pyrophosphohydrolase LpxH in lipid A biosynthesis utilizes Mn2+ cluster for catalysis. 
  • The X-ray structure of the PurR-guanine-purF operator complex reveals the contributions of complementary electrostatic surfaces and a water-mediated hydrogen bond to corepressor specificity and binding affinity. 
  • The backbone structure of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein is essentially identical to its mesophilic E. coli homolog. 
  • The bacterial effector AvrRxo1 inhibits vitamin B6 biosynthesis to promote infection in rice. 
  • The bacterial effector HopM1 suppresses PAMP-triggered oxidative burst and stomatal immunity. 
  • The biosynthesis of molybdopterin in Escherichia coli. Purification and characterization of the converting factor. 
  • The cell division protein MinD from Pseudomonas aeruginosa dominates the assembly of the MinC-MinD copolymers. 
  • The changes of nitric oxide production during the growth of Microcystis aerugrinosa. 
  • The conformations of the manganese transport regulator of Bacillus subtilis in its metal-free state. 
  • The crystal structure of a thermophilic glucose binding protein reveals adaptations that interconvert mono and di-saccharide binding sites. 
  • The crystal structure of the RsbN-σBldN complex from Streptomyces venezuelae defines a new structural class of anti-σ factor. 
  • The crystal structure of the TetR family transcriptional repressor SimR bound to DNA and the role of a flexible N-terminal extension in minor groove binding. 
  • The cyclophilin-like domain of Ran-binding protein-2 modulates selectively the activity of the ubiquitin-proteasome system and protein biogenesis. 
  • The development of therapeutic and preventive vaccines for gastric cancer and Helicobacter pylori. 
  • The discovery of the prokaryotic cytoskeleton: 25th anniversary. 
  • The effect of osmotic stress on the production of nukacin ISK-1 from Staphylococcus warneri ISK-1. 
  • The filamentous bacteriophage assembly proteins require the bacterial SecA protein for correct localization to the membrane. 
  • The gene coding for the Hrp pilus structural protein is required for type III secretion of Hrp and Avr proteins in Pseudomonas syringae pv. tomato. 
  • The importance of repairing stalled replication forks. 
  • The influence of the synergistic anion on iron chelation by ferric binding protein, a bacterial transferrin. 
  • The location of the carotenoid in the B800--850 light-harvesting pigment--protein complex from Rhodopseudomonas capsulata. 
  • The molecular mechanisms of allosteric mutations impairing MepR repressor function in multidrug-resistant strains of Staphylococcus aureus. 
  • The nucleotide messenger (p)ppGpp is an anti-inducer of the purine synthesis transcription regulator PurR in Bacillus. 
  • The posttranslational modification cascade to the thiopeptide berninamycin generates linear forms and altered macrocyclic scaffolds. 
  • The potential role of alpha 2-macroglobulin in the control of cysteine proteinases (gingipains) from Porphyromonas gingivalis. 
  • The relationship between ligand-binding thermodynamics and protein-ligand interaction forces measured by atomic force microscopy. 
  • The role of FeS clusters for molybdenum cofactor biosynthesis and molybdoenzymes in bacteria. 
  • The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions. 
  • The role of the supernumerary subunit of Rhodobacter sphaeroides cytochrome bc1 complex. 
  • The roles of positive and negative selection in the molecular evolution of insect endosymbionts. 
  • The staphylococcal QacR multidrug regulator binds a correctly spaced operator as a pair of dimers. 
  • The straight and curved conformation of FtsZ protofilaments-evidence for rapid exchange of GTP into the curved protofilament. 
  • The structural distribution of cooperative interactions in proteins: analysis of the native state ensemble. 
  • The structural mechanism for transcription activation by MerR family member multidrug transporter activation, N terminus. 
  • The structure of PurR mutant L54M shows an alternative route to DNA kinking. 
  • The structure of a high fidelity DNA polymerase bound to a mismatched nucleotide reveals an "ajar" intermediate conformation in the nucleotide selection mechanism. 
  • The symmetrical structure of structural maintenance of chromosomes (SMC) and MukB proteins: long, antiparallel coiled coils, folded at a flexible hinge. 
  • The triple threat of cryptococcosis: it's the body site, the strain, and/or the host. 
  • The tyrosine corner: a feature of most Greek key beta-barrel proteins. 
  • The vibrio cholerae hybrid sensor kinase VieS contributes to motility and biofilm regulation by altering the cyclic diguanylate level. 
  • Thermal stability of self-assembled peptide vaccine materials. 
  • Thermodynamic evaluation of binding interactions in the methionine repressor system of Escherichia coli using isothermal titration calorimetry. 
  • Thermodynamic stability measurements on multimeric proteins using a new H/D exchange- and matrix-assisted laser desorption/ionization (MALDI) mass spectrometry-based method. 
  • Three-in-one chromatography-free purification, tag removal, and site-specific modification of recombinant fusion proteins using sortase A and elastin-like polypeptides. 
  • Thrombocyte Inhibition Restores Protective Immunity to Mycobacterial Infection in Zebrafish. 
  • Tissue plasminogen activator (tPA) signal sequence enhances immunogenicity of MVA-based vaccine against tuberculosis. 
  • Tn5-mediated bleomycin resistance in Escherichia coli requires the expression of host genes. 
  • Total chemical synthesis of the B1 domain of protein L from Peptostreptococcus magnus. 
  • Trafficking of yellow-fluorescent-protein-tagged mu1 subunit of clathrin adaptor AP-1 complex in living cells. 
  • Trafficking patterns of beta-arrestin and G protein-coupled receptors determined by the kinetics of beta-arrestin deubiquitination. 
  • Transcription of the SsrAB regulon is repressed by alkaline pH and is independent of PhoPQ and magnesium concentration. 
  • Transcription-associated mutation of lasR in Pseudomonas aeruginosa. 
  • Transcriptome landscape of a bacterial pathogen under plant immunity. 
  • Transfer of CD8+ T cell memory using Bcl-2 as a marker. 
  • Transient Nutrient Deprivation Promotes Macropinocytosis-Dependent Intracellular Bacterial Community Development. 
  • Transmission of methicillin-resistant Staphylococcus aureus between human and hamster. 
  • Treatment with immunotoxin. 
  • Tuberculous granuloma induction via interaction of a bacterial secreted protein with host epithelium. 
  • Two CDC42 paralogues modulate Cryptococcus neoformans thermotolerance and morphogenesis under host physiological conditions. 
  • Two proteins encoded at the chlA locus constitute the converting factor of Escherichia coli chlA1. 
  • Two-dimensional crystallization and projection structure of KcsA potassium channel. 
  • Two-dimensional protein crystallization via metal-ion coordination by naturally occurring surface histidines. 
  • Type 1 fimbrial shafts of Escherichia coli and Klebsiella pneumoniae influence sugar-binding specificities of their FimH adhesins. 
  • Type III protein secretion in Pseudomonas syringae. 
  • Type III protein secretion in plant pathogenic bacteria. 
  • Type III protein secretion mechanism in mammalian and plant pathogens. 
  • Update on resistance of Bacteroides fragilis group and related species with special attention to carbapenems 2006-2009. 
  • Use of bacterial quorum-sensing components to regulate gene expression in plants. 
  • Use of dominant-negative HrpA mutants to dissect Hrp pilus assembly and type III secretion in Pseudomonas syringae pv. tomato. 
  • Use of monoclonal antibodies to probe subunit- and polymer-specific epitopes of 987P fimbriae of Escherichia coli. 
  • VanA rectal swab screening as a predictor of subsequent vancomycin-resistant enterococcal bloodstream infection in critically ill adults. 
  • Variation of molecular alignment as a means of resolving orientational ambiguities in protein structures from dipolar couplings. 
  • Versatile biomanufacturing through stimulus-responsive cell-material feedback. 
  • Vinyl sulfones: inhibitors of SrtA, a transpeptidase required for cell wall protein anchoring and virulence in Staphylococcus aureus. 
  • Visualization of secreted Hrp and Avr proteins along the Hrp pilus during type III secretion in Erwinia amylovora and Pseudomonas syringae. 
  • Visualizing reaction pathways in photoactive yellow protein from nanoseconds to seconds. 
  • When is a transcription factor a NAP? 
  • Whole genome re-sequencing to identify suppressor mutations of mutant and foreign Escherichia coli FtsZ. 
  • Widespread recombination throughout Wolbachia genomes. 
  • Yield of stool culture with isolate toxin testing versus a two-step algorithm including stool toxin testing for detection of toxigenic Clostridium difficile. 
  • Zebrafish as a neurotoxicological model. 
  • ZipA and FtsA* stabilize FtsZ-GDP miniring structures. 
  • c-di-GMP Arms an Anti-σ to Control Progression of Multicellular Differentiation in Streptomyces. 
  • fii, a bacterial locus required for filamentous phage infection and its relation to colicin-tolerant tolA and tolB. 
  • hMutSalpha- and hMutLalpha-dependent phosphorylation of p53 in response to DNA methylator damage. 
  • hrp gene-dependent induction of hin1: a plant gene activated rapidly by both harpins and the avrPto gene-mediated signal. 
  • ssDNA is an allosteric regulator of the C. crescentus SOS-independent DNA damage response transcription activator, DriD. 
  • ¹H, ¹³C, and ¹⁵N resonance assignments and secondary structure prediction of the full-length transition state regulator AbrB from Bacillus anthracis. 
• 

  Keywords of People

  • Bobay, Benjamin, Assistant Professor in Radiology, Radiology
  • Erickson, Harold Paul, James B. Duke Distinguished Professor Emeritus, Cell Biology
  • Ferreira, Paulo Alexandre, Associate Professor in Ophthalmology, Pathology
  • Kuehn, Margarethe Joanna, Associate Professor of Biochemistry, Cell Biology
  • Soderling, Scott Haydn, George Barth Geller Distinguished Professor of Molecular Biology, Cell Biology