-
Subject Areas on Research
-
2-Methylbutyryl-coenzyme A dehydrogenase deficiency: a new inborn error of L-isoleucine metabolism.
-
4-oxatetradecanoic acid is fungicidal for Cryptococcus neoformans and inhibits replication of human immunodeficiency virus I.
-
4.5 kb of the rat tyrosine hydroxylase 5' flanking sequence directs tissue specific expression during development and contains consensus sites for multiple transcription factors.
-
5' flanking DNA sequences direct cell-specific expression of rat tyrosine hydroxylase.
-
9-cis retinoic acid regulation of rat growth hormone gene expression: potential roles of multiple nuclear hormone receptors.
-
A 'Semi-Protected Oligonucleotide Recombination' Assay for DNA Mismatch Repair in vivo Suggests Different Modes of Repair for Lagging Strand Mismatches.
-
A 32 kb critical region excluding Y402H in CFH mediates risk for age-related macular degeneration.
-
A 38 base pair insertion in the pro alpha 2(I) collagen gene of a patient with Marfan syndrome.
-
A 40-kilodalton protein binds specifically to an upstream sequence element essential for muscle-specific transcription of the human myoglobin promoter.
-
A 43-nucleotide RNA cis-acting element governs the site-specific formation of the 3' end of a poxvirus late mRNA.
-
A 6-Mb high-resolution physical and transcription map encompassing the hereditary prostate cancer 1 (HPC1) region.
-
A B-cell-homing chemokine made in lymphoid follicles activates Burkitt's lymphoma receptor-1.
-
A C-terminal motif found in the beta2-adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator determines binding to the Na+/H+ exchanger regulatory factor family of PDZ proteins.
-
A Drosophila CREB/CREM homolog encodes multiple isoforms, including a cyclic AMP-dependent protein kinase-responsive transcriptional activator and antagonist.
-
A Model Information Management Plan for Molecular Pathology Sequence Data Using Standards: From Sequencer to Electronic Health Record.
-
A PAK-like protein kinase is required for maturation of young hyphae and septation in the filamentous ascomycete Ashbya gossypii.
-
A PHEX gene mutation is responsible for adult-onset vitamin D-resistant hypophosphatemic osteomalacia: evidence that the disorder is not a distinct entity from X-linked hypophosphatemic rickets.
-
A Rac homolog functions downstream of Ras1 to control hyphal differentiation and high-temperature growth in the pathogenic fungus Cryptococcus neoformans.
-
A STE12 homolog is required for mating but dispensable for filamentation in candida lusitaniae.
-
A T cell-specific transcriptional enhancer within the human T cell receptor delta locus.
-
A WAVE-1 and WRP signaling complex regulates spine density, synaptic plasticity, and memory.
-
A Xenopus egg factor with DNA-binding properties characteristic of terminus-specific telomeric proteins.
-
A bidirectional phage display vector for the selection and mass transfer of polyclonal antibody libraries.
-
A blood group-related polymorphism of CD44 abolishes a hyaluronan-binding consensus sequence without preventing hyaluronan binding.
-
A broad competence to respond to SHORT ROOT revealed by tissue-specific ectopic expression.
-
A cAMP response element in the beta 2-adrenergic receptor gene confers transcriptional autoregulation by cAMP.
-
A candidate gene for congenital bilateral isolated ptosis identified by molecular analysis of a de novo balanced translocation.
-
A cell-specific nuclear receptor is essential for adrenal and gonadal development and sexual differentiation.
-
A circular trans-acting hepatitis delta virus ribozyme.
-
A cis-acting sequence homologous to the yeast filamentation and invasion response element regulates expression of a pectinase gene from the bean pathogen Colletotrichum lindemuthianum.
-
A cluster of HIV type 1 subtype C sequences from Ethiopia, observed in full genome analysis, is not sustained in subgenomic regions.
-
A common RNA recognition motif identified within a defined U1 RNA binding domain of the 70K U1 snRNP protein.
-
A comparison of methods for RNA extraction from lymphocytes for RT-PCR.
-
A comparison of regulatory features in primate lentiviruses.
-
A comparison of sequencing platforms and bioinformatics pipelines for compositional analysis of the gut microbiome.
-
A compensatory base change in U1 snRNA suppresses a 5' splice site mutation.
-
A compensatory base change in human U2 snRNA can suppress a branch site mutation.
-
A complex intronic enhancer regulates expression of the CFTR gene by direct interaction with the promoter.
-
A compound nucleotide repeat in the neurofibromatosis (NF1) gene.
-
A comprehensive joint analysis of the long and short RNA transcriptomes of human erythrocytes.
-
A connection between stress and development in the multicellular prokaryote Streptomyces coelicolor A3(2).
-
A conserved alternative splice in the von Recklinghausen neurofibromatosis (NF1) gene produces two neurofibromin isoforms, both of which have GTPase-activating protein activity.
-
A conserved bulged adenosine in a peripheral duplex of the antigenomic HDV self-cleaving RNA reduceskinetic trapping of inactive conformations.
-
A conserved domain of the viviparous-1 gene product enhances the DNA binding activity of the bZIP protein EmBP-1 and other transcription factors.
-
A conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitors.
-
A conserved transcriptional enhancer regulates RAG gene expression in developing B cells.
-
A cooperative interaction between NF-kappa B and Sp1 is required for HIV-1 enhancer activation.
-
A critical role for the autophagy gene Atg5 in T cell survival and proliferation.
-
A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation.
-
A de novo frame-shift mutation in the tuberin gene.
-
A deletion unit on chromosome 17q in epithelial ovarian tumors distal to the familial breast/ovarian cancer locus.
-
A developmental switch from TCR delta enhancer to TCR alpha enhancer function during thymocyte maturation.
-
A distal enhancer and an ultraconserved exon are derived from a novel retroposon.
-
A distinct pattern of cytokine gene expression by human CD83+ blood dendritic cells.
-
A distinct wave of human T cell receptor gamma/delta lymphocytes in the early fetal thymus: evidence for controlled gene rearrangement and cytokine production.
-
A distinctive clade B HIV type 1 is heterosexually transmitted in Trinidad and Tobago.
-
A founder mutation in the Ashkenazi Jewish population affecting messenger RNA splicing of the CCM2 gene causes cerebral cavernous malformations.
-
A framework phylogeny of the American oak clade based on sequenced RAD data.
-
A functional antigenomic promoter for the paramyxovirus simian virus 5 requires proper spacing between an essential internal segment and the 3' terminus.
-
A functional isoform of the human granulocyte/macrophage colony-stimulating factor receptor has an unusual cytoplasmic domain.
-
A gain-of-function mutation in IAA16 confers reduced responses to auxin and abscisic acid and impedes plant growth and fertility.
-
A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes.
-
A gene on chromosome 11q23 coding for a putative glucose- 6-phosphate translocase is mutated in glycogen-storage disease types Ib and Ic.
-
A gene therapy strategy using a transcription factor decoy of the E2F binding site inhibits smooth muscle proliferation in vivo.
-
A genetic linkage map of the laboratory rat, Rattus norvegicus.
-
A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2.
-
A genomic survey of positive selection in Burkholderia pseudomallei provides insights into the evolution of accidental virulence.
-
A germline mutation at the extreme 3' end of the APC gene results in a severe desmoid phenotype and is associated with overexpression of beta-catenin in the desmoid tumor.
-
A high affinity, antidote-controllable prothrombin and thrombin-binding RNA aptamer inhibits thrombin generation and thrombin activity.
-
A high-resolution integrated physical, cytogenetic, and genetic map of human chromosome 11: distal p13 to proximal p15.1.
-
A highly conserved RNA folding region coincident with the Rev response element of primate immunodeficiency viruses.
-
A homozygous 5 base-pair deletion in exon 10 of the adenosine deaminase (ADA) gene in a child with severe combined immunodeficiency and very low levels of ADA mRNA and protein.
-
A homozygous mutation in the endothelin-3 gene associated with a combined Waardenburg type 2 and Hirschsprung phenotype (Shah-Waardenburg syndrome).
-
A host protein (La) binds to a unique species of minus-sense leader RNA during replication of vesicular stomatitis virus.
-
A hot spot for hydrogen peroxide-induced damage in the human hypoxia-inducible factor 1 binding site of the PGK 1 gene.
-
A human autoimmune protein associated with U1 RNA contains a region of homology that is cross-reactive with retroviral p30gag antigen.
-
A human novel gene DERPC on 16q22.1 inhibits prostate tumor cell growth and its expression is decreased in prostate and renal tumors.
-
A human protein related to yeast Cdc6p.
-
A large set of Finnish affected sibling pair families with type 2 diabetes suggests susceptibility loci on chromosomes 6, 11, and 14.
-
A linkage map reveals a complex basis for segregation distortion in an interpopulation cross in the moss Ceratodon purpureus.
-
A linking function for the cellulose-binding protein SP85 in the spore coat of Dictyostelium discoideum.
-
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia.
-
A maximum-likelihood base caller for DNA sequencing.
-
A member of a family of sulfate-activating enzymes causes murine brachymorphism.
-
A membrane-associated progesterone-binding protein, 25-Dx, is regulated by progesterone in brain regions involved in female reproductive behaviors.
-
A method for analysis of gene expression patterns.
-
A method for linking VL and VH region genes that allows bulk transfer between vectors for use in generating polyclonal IgG libraries.
-
A methylthioadenosine phosphorylase (MTAP) fusion transcript identifies a new gene on chromosome 9p21 that is frequently deleted in cancer.
-
A microarray analysis of the XX Wnt4 mutant gonad targeted at the identification of genes involved in testis vascular differentiation.
-
A microarray analysis of the XX Wnt4 mutant gonad targeted at the identification of genes involved in testis vascular differentiation.
-
A missense mutation in exon 4 of the human adenosine deaminase gene causes severe combined immunodeficiency.
-
A molecular clasp in the human immunodeficiency virus (HIV) type 1 TM protein determines the anti-HIV activity of gp41 derivatives: implication for viral fusion.
-
A molecular genetic study of intracerebral hemorrhage.
-
A mouse homoeo box gene is expressed during embryogenesis and in adult kidney.
-
A multi-locus molecular phylogeny of the Lepidoziaceae: laying the foundations for a stable classification.
-
A multilocus sequence survey in Arabidopsis thaliana reveals a genome-wide departure from a neutral model of DNA sequence polymorphism.
-
A mutation in Arabidopsis that leads to constitutive expression of systemic acquired resistance.
-
A naturally occurring gamma globin gene mutation enhances SP1 binding activity.
-
A nested double pseudoknot is required for self-cleavage activity of both the genomic and antigenomic hepatitis delta virus ribozymes.
-
A neural survival factor is a candidate oncogene in breast cancer.
-
A new H/D exchange- and mass spectrometry-based method for thermodynamic analysis of protein-DNA interactions.
-
A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes.
-
A non-lens member of the beta gamma-crystallin superfamily in a vertebrate, the amphibian Cynops.
-
A novel Ca2+/calmodulin-dependent protein kinase and a male germ cell-specific calmodulin-binding protein are derived from the same gene.
-
A novel T-77C polymorphism in DNA repair gene XRCC1 contributes to diminished promoter activity and increased risk of non-small cell lung cancer.
-
A novel antibody humanization method based on epitopes scanning and molecular dynamics simulation.
-
A novel basal promoter element is required for expression of the rat tyrosine hydroxylase gene.
-
A novel beta-globin mutation, beta Durham-NC [beta 114 Leu-->Pro], produces a dominant thalassemia-like phenotype.
-
A novel cell-surface molecule expressed by human interdigitating reticulum cells, Langerhans cells, and activated lymphocytes is a new member of the Ig superfamily.
-
A novel human endogenous retroviral protein inhibits cell-cell fusion.
-
A novel leptin receptor isoform in rat.
-
A novel long and unstable CAG/CTG trinucleotide repeat on chromosome 17q.
-
A novel mitochondrial septin-like protein, ARTS, mediates apoptosis dependent on its P-loop motif.
-
A novel modifier gene for plasma von Willebrand factor level maps to distal mouse chromosome 11.
-
A novel mutation in the von Hippel-Lindau gene.
-
A novel polypeptide secreted by activated human T lymphocytes.
-
A novel potassium channel with delayed rectifier properties isolated from rat brain by expression cloning.
-
A novel species-specific RNA related to alternatively spliced amyloid precursor protein mRNAs.
-
A novel thermostable branching enzyme from an extremely thermophilic bacterial species, Rhodothermus obamensis.
-
A novel two-component hybrid molecule regulates vascular morphogenesis of the Arabidopsis root.
-
A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex.
-
A novel, highly regulated, rapidly inducible system for the expression of chicken progesterone receptor, cPRA, in Saccharomyces cerevisiae.
-
A pH-sensitive RNA tertiary interaction affects self-cleavage activity of the HDV ribozymes in the absence of added divalent metal ion.
-
A patient with Ehlers-Danlos syndrome type VI is a compound heterozygote for mutations in the lysyl hydroxylase gene.
-
A phosphorylated cytoplasmic autoantigen, GW182, associates with a unique population of human mRNAs within novel cytoplasmic speckles.
-
A physical map across chromosome 11q22-q23 containing the major locus for ataxia telangiectasia.
-
A potential role for glucose transporters in the evolution of human brain size.
-
A potential role for interferon-alpha in the pathogenesis of HIV-associated dementia.
-
A poxvirus-derived vector that directs high levels of expression of cloned genes in mammalian cells.
-
A pseudoknot in the 3' non-core region of the glmS ribozyme enhances self-cleavage activity.
-
A pseudoknot-like structure required for efficient self-cleavage of hepatitis delta virus RNA.
-
A radiation hybrid map of the distal short arm of human chromosome 11, containing the Beckwith-Wiedemann and associated embryonal tumor disease loci.
-
A re-evaluation of 12S ribosomal RNA variability in Drosophila pseudoobscura.
-
A recombination-based assay demonstrates that the fragile X sequence is transcribed widely during development.
-
A role for Sp and nuclear receptor transcription factors in a cardiac hypertrophic growth program.
-
A role for the Ppz Ser/Thr protein phosphatases in the regulation of translation elongation factor 1Balpha.
-
A role for the cytoplasmic tail of the beta chain of CD8 in thymic selection.
-
A role for the orphan steroid receptor Nur77 in apoptosis accompanying antigen-induced negative selection.
-
A sensitive genetic assay for the detection of cytosine deamination: determination of rate constants and the activation energy.
-
A sensitized mutagenesis screen identifies Gli3 as a modifier of Sox10 neurocristopathy.
-
A sequence-specific conformational epitope on U1 RNA is recognized by a unique autoantibody.
-
A serum-resistant cytofectin for cellular delivery of antisense oligodeoxynucleotides and plasmid DNA.
-
A simple BASIC program allows the rapid entry of DNA nucleotide sequences into personal computers.
-
A single amino acid change in the cytoplasmic domain of the simian immunodeficiency virus transmembrane molecule increases envelope glycoprotein expression on infected cells.
-
A single amino acid change in the para sodium channel protein is associated with knockdown-resistance (kdr) to pyrethroid insecticides in German cockroach.
-
A single nucleotide linked to a switch in metal ion reactivity preference in the HDV ribozymes.
-
A single stem-loop structure within the HTLV-1 Rex response element is sufficient to mediate Rex activity in vivo.
-
A small interfering RNA screen for modulators of tumor cell motility identifies MAP4K4 as a promigratory kinase.
-
A somatic TSHR mutation in a patient with lung adenocarcinoma with bronchioloalveolar carcinoma, coronary artery disease and severe chronic obstructive pulmonary disease.
-
A specific 31-nucleotide domain of U1 RNA directly interacts with the 70K small nuclear ribonucleoprotein component.
-
A specific internal RNA polymerase recognition site of VSV RNA is involved in the generation of DI particles.
-
A splice junction mutation in a new myopathic variant of phosphoglycerate kinase deficiency (PGK North Carolina).
-
A standardized approach to PCR-based semiquantitation of multiple cytokine gene transcripts from small cell samples.
-
A strong effect of AT mutational bias on amino acid usage in Buchnera is mitigated at high-expression genes.
-
A structural basis for a phosphoramide mustard-induced DNA interstrand cross-link at 5'-d(GAC).
-
A structural perspective on the where, how, why, and what of nucleosome positioning.
-
A sulfurtransferase is required in the transfer of cysteine sulfur in the in vitro synthesis of molybdopterin from precursor Z in Escherichia coli.
-
A surface of Escherichia coli sigma 70 required for promoter function and antitermination by phage lambda Q protein.
-
A synthetic random basic copolymer with promiscuous binding to class II major histocompatibility complex molecules inhibits T-cell proliferative responses to major and minor histocompatibility antigens in vitro and confers the capacity to prevent murine graft-versus-host disease in vivo.
-
A system of transposon mutagenesis for bacteriophage T4.
-
A thioesterase bypasses the requirement for exogenous fatty acids in the plsX deletion of Streptococcus pneumoniae.
-
A toggle duplex in hepatitis delta virus self-cleaving RNA that stabilizes an inactive and a salt-dependent pro-active ribozyme conformation.
-
A transcriptional repressor of osteopontin expression in the 4T1 murine breast cancer cell line.
-
A universal molecular method for identifying underground plant parts to species.
-
A user's guide to the encyclopedia of DNA elements (ENCODE).
-
A yeast artificial chromosome contig encompassing the type 1 neurofibromatosis gene.
-
A yeast cyclophilin gene essential for lactate metabolism at high temperature.
-
A yeast expression system for human galactose-1-phosphate uridylyltransferase.
-
ABL1 promoter methylation can exist independently of BCR-ABL transcription in chronic myeloid leukemia hematopoietic progenitors.
-
ACE and ACE2 activity in diabetic mice.
-
ATM binds to beta-adaptin in cytoplasmic vesicles.
-
Abasic sites in the transcribed strand of yeast DNA are removed by transcription-coupled nucleotide excision repair.
-
Abelson kinase (Abl) and RhoGEF2 regulate actin organization during cell constriction in Drosophila.
-
Aberrant splicing of the TSG101 tumor suppressor gene in human breast and ovarian cancers.
-
Abh and AbrB control of Bacillus subtilis antimicrobial gene expression.
-
Abrogation of P53 function by transfection of HPV16 E6 gene does not enhance resistance of human tumour cells to ionizing radiation.
-
Abrogation of p53 function by transfection of HPV16 E6 gene enhances the resistance of human diploid fibroblasts to ionizing radiation.
-
Absence of mutation in the beta-amyloid cDNAs cloned from the brains of three patients with sporadic Alzheimer's disease.
-
Absence of radiation-induced G1 arrest in two closely related human lymphoblast cell lines that differ in p53 status.
-
Absence of recoverable infectious virus and unique immune responses in an asymptomatic HIV+ long-term survivor.
-
Abundant gene conversion between arms of palindromes in human and ape Y chromosomes.
-
Accelerated deamination of cytosine residues in UV-induced cyclobutane pyrimidine dimers leads to CC-->TT transitions.
-
Activated cAMP-response element-binding protein regulates neuronal expression of presenilin-1.
-
Activating human genes with zinc finger proteins, transcription activator-like effectors and CRISPR/Cas9 for gene therapy and regenerative medicine.
-
Activation of Galpha q-coupled signaling pathways in glomerular podocytes promotes renal injury.
-
Activation of arterial wall dendritic cells and breakdown of self-tolerance in giant cell arteritis.
-
Activation of fibroblast growth factor (FGF) receptors by recombinant human FGF-5.
-
Activation of tat-defective human immunodeficiency virus by ultraviolet light.
-
Activation of the heat shock transcription factor by hypoxia in mammalian cells.
-
Activity of a Py-Im polyamide targeted to the estrogen response element.
-
Activity of a type 1 picornavirus internal ribosomal entry site is determined by sequences within the 3' nontranslated region.
-
Acute suppression of insulin resistance-associated hepatic miR-29 in vivo improves glycemic control in adult mice.
-
Acute vascular rejection and accommodation: divergent outcomes of the humoral response to organ transplantation.
-
Acyl carrier protein-specific 4'-phosphopantetheinyl transferase activates 10-formyltetrahydrofolate dehydrogenase.
-
Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug Tolerance.
-
Addition of molecular methods to mutation studies with Drosophila melanogaster.
-
Adducin is an in vivo substrate for protein kinase C: phosphorylation in the MARCKS-related domain inhibits activity in promoting spectrin-actin complexes and occurs in many cells, including dendritic spines of neurons.
-
Adenosine deaminase (ADA) deficiency due to deletion of the ADA gene promoter and first exon by homologous recombination between two Alu elements.
-
Adenosine deaminase deficiency with mosaicism for a "second-site suppressor" of a splicing mutation: decline in revertant T lymphocytes during enzyme replacement therapy.
-
Adenosine-deaminase-deficient mice die perinatally and exhibit liver-cell degeneration, atelectasis and small intestinal cell death.
-
Adenylyl cyclase functions downstream of the Galpha protein Gpa1 and controls mating and pathogenicity of Cryptococcus neoformans.
-
Advantages of mRNA amplification for microarray analysis.
-
African strains of hepatitis E virus that are distinct from Asian strains.
-
Age distribution of latent herpes simplex virus 1 and varicella-zoster virus genome in human nervous tissue.
-
Allele separation facilitates interpretation of potential splicing alterations and genomic rearrangements.
-
Allele-specific assay reveals functional variation in the chalcone synthase promoter of Arabidopsis thaliana that is compatible with neutral evolution.
-
Allelic and locus heterogeneity in inherited venous malformations.
-
Allelic loss at the tuberous sclerosis 2 locus in spontaneous tumors in the Eker rat.
-
Allogeneic bone marrow transplantation for treatment of severe hemolytic anemia attributable to hexokinase deficiency.
-
Alteration of the alkaloid profile in genetically modified tobacco reveals a role of methylenetetrahydrofolate reductase in nicotine N-demethylation.
-
Alteration of the tumor suppressor gene p53 in a high fraction of hormone refractory prostate cancer.
-
Alterations of the P53 gene are associated with the progression of a human prostate carcinoma.
-
Altered interaction of Cis-dichlorodiammineplatinum(II)--modified alpha 2-macroglobulin (alpha 2M) with the low density lipoprotein receptor-related protein/alpha 2M receptor but not the alpha 2M signaling receptor.
-
Alternative processing of androgen-binding protein RNA transcripts in fetal rat liver. Identification of a transcript formed by trans splicing.
-
Alternative splicing in Acad8 resulting a mitochondrial defect and progressive hepatic steatosis in mice.
-
Alternative splicing of an insect sodium channel gene generates pharmacologically distinct sodium channels.
-
Alternative splicing of the BSC1 gene generates tissue-specific isoforms in the German cockroach.
-
Alternative splicing: a mechanism for phenotypic rescue of a common inherited defect.
-
Alternative translation initiation site usage results in two structurally distinct forms of Pit-1.
-
Alu-PCR fingerprinting of YACs.
-
Alveolar rhabdomyosarcoma-associated PAX3-FOXO1 promotes tumorigenesis via Hippo pathway suppression.
-
Amino acids important in enzyme activity and dimer stability for Drosophila alcohol dehydrogenase.
-
Amplification of HIV-1 provirus from cerebrospinal fluid and its correlation with neurologic disease.
-
Amplification of a complete simian immunodeficiency virus genome from fecal RNA of a wild chimpanzee.
-
Amplification of bacterial 16S ribosomal DNA with polymerase chain reaction.
-
Amplified on-chip fluorescence detection of DNA hybridization by surface-initiated enzymatic polymerization.
-
An Arabidopsis thaliana lipoxygenase gene can be induced by pathogens, abscisic acid, and methyl jasmonate.
-
An EcoRI-RsrI chimeric restriction endonuclease retains parental sequence specificity.
-
An algorithm for the reconstruction of consensus sequences of ancient segmental duplications and transposon copies in eukaryotic genomes.
-
An alternative splice form of Mdm2 induces p53-independent cell growth and tumorigenesis.
-
An antitumor drug-induced topoisomerase cleavage complex blocks a bacteriophage T4 replication fork in vivo.
-
An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1.
-
An essential role for Mad homology domain 1 in the association of Smad3 with histone deacetylase activity*.
-
An extensive de novo deletion removing FMR1 in a patient with mental retardation and the fragile X syndrome phenotype.
-
An imaging-based approach to identify ligands for olfactory receptors.
-
An imprinted PEG1/MEST antisense expressed predominantly in human testis and in mature spermatozoa.
-
An in vivo expression technology screen for Vibrio cholerae genes expressed in human volunteers.
-
An internalization signal in the simian immunodeficiency virus transmembrane protein cytoplasmic domain modulates expression of envelope glycoproteins on the cell surface.
-
An intron facilitates activation of the calspermin gene by the testis-specific transcription factor CREM tau.
-
An intronless gene encoding a potential member of the family of receptors coupled to guanine nucleotide regulatory proteins.
-
An isolate of human immunodeficiency virus type 1 originally classified as subtype I represents a complex mosaic comprising three different group M subtypes (A, G, and I).
-
An miR-502-binding site single-nucleotide polymorphism in the 3'-untranslated region of the SET8 gene is associated with early age of breast cancer onset.
-
An oligonucleotide decoy for transcription factor E2F inhibits mesangial cell proliferation in vitro.
-
Analysis of CpG methylation in the killifish CYP1A promoter.
-
Analysis of DNA methylation in a three-generation family reveals widespread genetic influence on epigenetic regulation.
-
Analysis of Drosophila melanogaster satellite IV with restriction endonuclease MboII.
-
Analysis of ENU-induced mutations at the Adh locus in Drosophila melanogaster.
-
Analysis of a gene conversion gradient at the HIS4 locus in Saccharomyces cerevisiae.
-
Analysis of cDNA for human erythrocyte ankyrin indicates a repeated structure with homology to tissue-differentiation and cell-cycle control proteins.
-
Analysis of cleavage complexes using reactive inhibitor derivatives.
-
Analysis of genes coding for small-subunit rRNA sequences in studying phylogenetics of dematiaceous fungal pathogens.
-
Analysis of globin gene structure in patients with beta thalassemia by restriction endonuclease mapping.
-
Analysis of messenger ribonucleic acid and protein for the ligands and receptors of the platelet-derived growth factor signaling pathway in the placenta, extraembryonic membranes, and uterus during the latter half of murine gestation.
-
Analysis of methylation-sensitive transcriptome identifies GADD45a as a frequently methylated gene in breast cancer.
-
Analysis of muscle creatine kinase regulatory elements in recombinant adenoviral vectors.
-
Analysis of recombinant Phex: an endopeptidase in search of a substrate.
-
Analysis of repetitive sequence elements containing tRNA-like sequences.
-
Analysis of the RNA binding specificity of the human tap protein, a constitutive transport element-specific nuclear RNA export factor.
-
Analysis of the effect of natural sequence variation in Tat and in cyclin T on the formation and RNA binding properties of Tat-cyclin T complexes.
-
Analysis of the gene encoding the largest subunit of RNA polymerase II in Drosophila.
-
Analysis of the indel at the ARMS2 3'UTR in age-related macular degeneration.
-
Analysis of the junction between ribosomal RNA genes and single-copy chromosomal sequences in the yeast Saccharomyces cerevisiae.
-
Analysis of the neurofibromatosis type 1 (NF1) GAP-related domain by site-directed mutagenesis.
-
Analysis of the protein products encoded by variant glucokinase transcripts via expression in bacteria.
-
Analysis of the structural properties of cAMP-responsive element-binding protein (CREB) and phosphorylated CREB.
-
Analysis of trans activation by human papillomavirus type 16 E7 and adenovirus 12S E1A suggests a common mechanism.
-
Analysis of trans-acting response decoy RNA-mediated inhibition of human immunodeficiency virus type 1 transactivation.
-
Analytical DNA fingerprinting in lions: parentage, genetic diversity, and kinship.
-
Ancient DNA from giant extinct lemurs confirms single origin of Malagasy primates.
-
Ancient and recent patterns of geographic speciation in the oyster mushroom Pleurotus revealed by phylogenetic analysis of ribosomal DNA sequences.
-
Ancient and recent positive selection transformed opioid cis-regulation in humans.
-
Ancient bacterial endosymbionts of insects: Genomes as sources of insight and springboards for inquiry.
-
Androgen receptor mutations in androgen-independent prostate cancer: Cancer and Leukemia Group B Study 9663.
-
Androgen-induced expression of endoplasmic reticulum (ER) stress response genes in prostate cancer cells.
-
Angiogenic effects of interleukin 8 (CXCL8) in human intestinal microvascular endothelial cells are mediated by CXCR2.
-
Angiotensin II type 2 receptor mediates programmed cell death.
-
Angiotensin converting enzyme and genetic hypertension: cloning of rat cDNAs and characterization of the enzyme.
-
Animal model for maturity-onset diabetes of the young generated by disruption of the mouse glucokinase gene.
-
AnkyrinG is required for clustering of voltage-gated Na channels at axon initial segments and for normal action potential firing.
-
AnkyrinG. A new ankyrin gene with neural-specific isoforms localized at the axonal initial segment and node of Ranvier.
-
Antagonism between apolipoprotein AI regulatory protein 1, Ear3/COUP-TF, and hepatocyte nuclear factor 4 modulates apolipoprotein CIII gene expression in liver and intestinal cells.
-
Antagonism of catecholamine receptor signaling by expression of cytoplasmic domains of the receptors.
-
Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation.
-
Anti-synthetic peptide antibody reacting at the fusion junction of deletion-mutant epidermal growth factor receptors in human glioblastoma.
-
Antiidiotypic antibody recognizes an amiloride binding domain within the alpha subunit of the epithelial Na+ channel.
-
Antimicrobial resistance to ceftazidime involving loss of penicillin-binding protein 3 in Burkholderia pseudomallei.
-
Antiretroviral monotherapy in early stage human immunodeficiency virus disease has no detectable effect on virus load in peripheral blood and lymph nodes.
-
Antisense DNA downregulation of the ERBB2 oncogene measured by a flow cytometric assay.
-
Antisense inhibition of group II phospholipase A2 expression blocks the production of prostaglandin E2 by P388D1 cells.
-
Antisense oligonucleotides directed at cell cycle regulatory genes as strategy for restenosis therapy.
-
Antitermination by bacteriophage lambda Q protein.
-
Antiviral antibodies are necessary for control of simian immunodeficiency virus replication.
-
Application of random peptide phage display to the study of nuclear hormone receptors.
-
Aptamer-mediated delivery of chemotherapy to pancreatic cancer cells.
-
Aptamers selected against the unglycosylated EGFRvIII ectodomain and delivered intracellularly reduce membrane-bound EGFRvIII and induce apoptosis.
-
Aquaporins in Saccharomyces. Genetic and functional distinctions between laboratory and wild-type strains.
-
Aquaporins in Saccharomyces: Characterization of a second functional water channel protein.
-
Arabidopsis PIS1 encodes the ABCG37 transporter of auxinic compounds including the auxin precursor indole-3-butyric acid.
-
Arabidopsis cDNA sequence encoding myrosinase.
-
Arachidonic acid mobilization in P388D1 macrophages is controlled by two distinct Ca(2+)-dependent phospholipase A2 enzymes.
-
Arrested rearrangement of TCR V beta genes in thymocytes from children with X-linked severe combined immunodeficiency disease.
-
Arsenic trioxide uptake by human and rat aquaglyceroporins.
-
Artifactual frame-shift p53 mutation at codon 249 detected with the Cyclist DNA sequencing method.
-
Assessing transcription factor motif drift from noisy decoy sequences.
-
Assessment of disparate structural features in three models of the hepatitis delta virus ribozyme.
-
Assignment of human transforming growth factor-beta type I and type III receptor genes (TGFBR1 and TGFBR3) to 9q33-q34 and 1p32-p33, respectively.
-
Assignment of the agent of Tyzzer's disease to Clostridium piliforme comb. nov. on the basis of 16S rRNA sequence analysis.
-
Assignment of the human beta-adducin gene (ADD2) to 2p13-p14 by in situ hybridization.
-
Association between putative functional variants in the PSMB9 gene and risk of melanoma--re-analysis of published melanoma genome-wide association studies.
-
Association of 3' terminal RNA sequences with avian leukosis viruses causing a high incidence of osteopetrosis.
-
Association of GRIK4 with outcome of antidepressant treatment in the STAR*D cohort.
-
Association of a functional tandem repeats in the downstream of human telomerase gene and lung cancer.
-
Association of angiotensinogen gene T235 variant with increased risk of coronary heart disease.
-
Association of genetic polymorphisms of ER-alpha and the estradiol-synthesizing enzyme genes CYP17 and CYP19 with breast cancer risk in Chinese women.
-
Association of genomic subtypes of lower-grade gliomas with shape features automatically extracted by a deep learning algorithm.
-
Association of misexpression with sterility in hybrids of Drosophila simulansand D. mauritiana.
-
Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease.
-
Association study of genetic polymorphisms of SLC2A10 gene and type 2 diabetes in the Taiwanese population.
-
Augmentation of immune responses to HIV-1 and simian immunodeficiency virus DNA vaccines by IL-2/Ig plasmid administration in rhesus monkeys.
-
AutoCSA, an algorithm for high throughput DNA sequence variant detection in cancer genomes.
-
Autoantibodies to the alpha/beta T-cell receptors in human immunodeficiency virus infection: dysregulation and mimicry.
-
Autofeedback suppression of growth hormone (GH) secretion in transgenic mice expressing a human GH reporter targeted by tyrosine hydroxylase 5'-flanking sequences to the hypothalamus.
-
Autoimmune epitopes in messenger RNA.
-
Autosomal-dominant distal myopathy associated with a recurrent missense mutation in the gene encoding the nuclear matrix protein, matrin 3.
-
B-CAM/LU expression and the role of B-CAM/LU activation in binding of low- and high-density red cells to laminin in sickle cell disease.
-
B-DNA to zip-DNA: simulating a DNA transition to a novel structure with enhanced charge-transport characteristics.
-
B56-associated protein phosphatase 2A is required for survival and protects from apoptosis in Drosophila melanogaster.
-
BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias.
-
BDNF regulates the maturation of inhibition and the critical period of plasticity in mouse visual cortex.
-
BP1, a homeodomain-containing isoform of DLX4, represses the beta-globin gene.
-
BRCA1 maps proximal to D17S579 on chromosome 17q21 by genetic analysis.
-
BRCA1 mutations in primary breast and ovarian carcinomas.
-
BRCA2 mutations in primary breast and ovarian cancers.
-
Bacterial DNA induces murine interferon-gamma production by stimulation of interleukin-12 and tumor necrosis factor-alpha.
-
Bacteriophage T4 mutants hypersensitive to an antitumor agent that induces topoisomerase-DNA cleavage complexes.
-
Bacteriophage flux in endosymbionts (Wolbachia): infection frequency, lateral transfer, and recombination rates.
-
Balloon catheterization induced arterial expression of embryonic fibronectins.
-
Bartonella henselae: etiology of pulmonary nodules in a patient with depressed cell-mediated immunity.
-
Bartonella vinsonii subsp. berkhoffii subsp. nov., isolated from dogs; Bartonella vinsonii subsp. vinsonii; and emended description of Bartonella vinsonii.
-
Base-pairing potential identified by in vitro selection predicts the kinked RNA backbone observed in the crystal structure of the alfalfa mosaic virus RNA-coat protein complex.
-
Basic matrices for the matrix-assisted laser desorption/ionization mass spectrometry of proteins and oligonucleotides.
-
Beta-adrenergic receptor kinase: primary structure delineates a multigene family.
-
Beta-thalassemia resulting from a single nucleotide substitution in an acceptor splice site.
-
Betadoublet: de novo design, synthesis, and characterization of a beta-sandwich protein.
-
Beyond bacteria: a study of the enteric microbial consortium in extremely low birth weight infants.
-
Biallelic Mutations in ATP5F1D, which Encodes a Subunit of ATP Synthase, Cause a Metabolic Disorder.
-
Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers.
-
Biallelic somatic and germline mutations in cerebral cavernous malformations (CCMs): evidence for a two-hit mechanism of CCM pathogenesis.
-
Bidirectional excision in methyl-directed mismatch repair.
-
Binding of MetJ repressor to specific and nonspecific DNA and effect of S-adenosylmethionine on these interactions.
-
Binding of the global response regulator protein CovR to the sag promoter of Streptococcus pyogenes reveals a new mode of CovR-DNA interaction.
-
Binding site for C4b-binding protein in vitamin K-dependent protein S fully contained in carboxy-terminal laminin-G-type repeats. A study using recombinant factor IX-protein S chimeras and surface plasmon resonance.
-
Binding site graphs: a new graph theoretical framework for prediction of transcription factor binding sites.
-
Biochemical characterization of the multifunctional Ca2+/calmodulin-dependent protein kinase type IV expressed in insect cells.
-
Bioinformatic design of A-kinase anchoring protein-in silico: a potent and selective peptide antagonist of type II protein kinase A anchoring.
-
Biological, immunological, and biochemical evidence that HIX virus is a recombinant between Moloney leukemia virus and a murine xenotropic C type virus.
-
Biological, molecular, and structural analysis of a cytopathic variant from a molecularly cloned simian immunodeficiency virus.
-
Biphasic induction of immediate early gene expression accompanies activity-dependent angiogenesis and myofiber remodeling of rabbit skeletal muscle.
-
Bisulfite induces tandem double CC-->TT mutations in double-stranded DNA. 2. Kinetics of cytosine deamination.
-
Bisulfite sequencing of cloned alleles.
-
Blinded evaluation of reverse transcriptase-polymerase chain reaction prostate-specific antigen peripheral blood assay for molecular staging of prostate cancer.
-
Blocking the initiation of coagulation by RNA aptamers to factor VIIa.
-
Bombesin and [Leu8]phyllolitorin promote fetal mouse lung branching morphogenesis via a receptor-mediated mechanism.
-
Bone morphogenetic protein 8A plays a role in the maintenance of spermatogenesis and the integrity of the epididymis.
-
Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse.
-
Boosting of HIV-1 neutralizing antibody responses by a distally related retroviral envelope protein.
-
Boron-containing aptamers to ATP.
-
Boron-containing oligodeoxyribonucleotide 14mer duplexes: enzymatic synthesis and melting studies.
-
Breakage of single-stranded DNA by eukaryotic type 1 topoisomerase occurs only at regions with the potential for base-pairing.
-
Breakpoints of the t(11;18)(q21;q21) in mucosa-associated lymphoid tissue (MALT) lymphoma lie within or near the previously undescribed gene MALT1 in chromosome 18.
-
Brief report: hepatic dysfunction as a complication of adenosine deaminase deficiency.
-
Brief report: lymphoma of donor origin occurring in the porta hepatis of a transplanted liver.
-
Broad-spectrum virus resistance in transgenic plants expressing pokeweed antiviral protein.
-
Buthionine sulfoximine induction of gamma-L-glutamyl-L-cysteine synthetase gene expression, kinetics of glutathione depletion and resynthesis, and modulation of carmustine-induced DNA-DNA cross-linking and cytotoxicity in human glioma cells.
-
C-terminally truncated derivatives of Escherichia coli Hfq are proficient in riboregulation.
-
CD10/NEP in non-small cell lung carcinomas. Relationship to cellular proliferation.
-
CD19 maps to a region of conservation between human chromosome 16 and mouse chromosome 7.
-
CD30 contains two binding sites with different specificities for members of the tumor necrosis factor receptor-associated factor family of signal transducing proteins.
-
CD69 gene is differentially regulated in T and B cells by evolutionarily conserved promoter-distal elements.
-
CDKN2 in HPV-positive and HPV-negative cervical-carcinoma cell lines.
-
CHST1 and CHST2 sulfotransferases expressed by human vascular endothelial cells: cDNA cloning, expression, and chromosomal localization.
-
CLL cell apoptosis induced by nitric oxide synthase inhibitors: correlation with lipid solubility and NOS1 dissociation constant.
-
COBRA encodes a putative GPI-anchored protein, which is polarly localized and necessary for oriented cell expansion in Arabidopsis.
-
COL5A1: fine genetic mapping and exclusion as candidate gene in families with nail-patella syndrome, tuberous sclerosis 1, hereditary hemorrhagic telangiectasia, and Ehlers-Danlos Syndrome type II.
-
COOH-terminal requirements for the correct processing of a phosphatidylinositol-glycan anchored membrane protein.
-
CRISPR Clocks: The Times They Are a-Changin'.
-
CTD kinase large subunit is encoded by CTK1, a gene required for normal growth of Saccharomyces cerevisiae.
-
CYP2C9*1B promoter polymorphisms, in linkage with CYP2C19*2, affect phenytoin autoinduction of clearance and maintenance dose.
-
Cadherin-11 expressed in association with mesenchymal morphogenesis in the head, somite, and limb bud of early mouse embryos.
-
Caenorhabditis elegans cog-1 locus encodes GTX/Nkx6.1 homeodomain proteins and regulates multiple aspects of reproductive system development.
-
Calcineurin is essential for survival during membrane stress in Candida albicans.
-
Calcineurin is essential in cyclosporin A- and FK506-sensitive yeast strains.
-
Calcineurin is required for virulence of Cryptococcus neoformans.
-
Calcineurin mutants render T lymphocytes resistant to cyclosporin A.
-
Calcineurin regulatory subunit is essential for virulence and mediates interactions with FKBP12-FK506 in Cryptococcus neoformans.
-
Calcium-sensitive potassium channelopathy in human epilepsy and paroxysmal movement disorder.
-
Calcium/calmodulin-dependent protein kinase types II and IV differentially regulate CREB-dependent gene expression.
-
Callipyge mutation affects gene expression in cis: a potential role for chromatin structure.
-
Calmodulin activation of target enzymes. Consequences of deletions in the central helix.
-
Calmodulin-cardiac troponin C chimeras. Effects of domain exchange on calcium binding and enzyme activation.
-
Calreticulin chaperones regulate functional expression of vomeronasal type 2 pheromone receptors.
-
Calspermin gene transcription is regulated by two cyclic AMP response elements contained in an alternative promoter in the calmodulin kinase IV gene.
-
Candidate genes mediating magnetoreception in rainbow trout (Oncorhynchus mykiss).
-
Canine model and genomic structural organization of glycogen storage disease type Ia (GSD Ia).
-
Carbonic anhydrase and CO2 sensing during Cryptococcus neoformans growth, differentiation, and virulence.
-
Cardiac BIN1 folds T-tubule membrane, controlling ion flux and limiting arrhythmia.
-
Cardiac hypertrophy and sudden death in mice with a genetically clamped renin transgene.
-
Cardiovascular phenotype of mice lacking all three subtypes of angiotensin II receptors.
-
Case-control analysis of thymidylate synthase polymorphisms and risk of lung cancer.
-
Caspase 8 is absent or low in many ex vivo gliomas.
-
Caspase-8 levels affect necessity for mitochondrial amplification in death ligand-induced glioma cell apoptosis.
-
Catalytic properties of the HhaII restriction endonuclease.
-
Cell binding specificity of mouse R-cadherin and chromosomal mapping of the gene.
-
Cell- and heparin-binding domains of the hexabrachion arm identified by tenascin expression proteins.
-
Cells treated with TAP-2 antisense oligonucleotides are potent antigen-presenting cells in vitro and in vivo.
-
Cellular CD44S as a determinant of human immunodeficiency virus type 1 infection and cellular tropism.
-
Cellular expression of the carboxyl terminus of a G protein-coupled receptor kinase attenuates G beta gamma-mediated signaling.
-
Cellular interaction in germinal centers. Roles of CD40 ligand and B7-2 in established germinal centers.
-
Cellular localization and effect of nitric oxide synthesis in a rat model of orthotopic liver transplantation.
-
Cellular mechanisms regulating protein phosphatase-1. A key functional interaction between inhibitor-2 and the type 1 protein phosphatase catalytic subunit.
-
Characteristics of Rhizobium tianshanense sp. nov., a moderately and slowly growing root nodule bacterium isolated from an arid saline environment in Xinjiang, People's Republic of China.
-
Characteristics of the interaction of a synthetic human tristetraprolin tandem zinc finger peptide with AU-rich element-containing RNA substrates.
-
Characterization and crystal structure of Escherichia coli KDPGal aldolase.
-
Characterization and expression of a rice RAD23 gene.
-
Characterization and expression of the complementary DNA encoding rat histidine decarboxylase.
-
Characterization and expression of the unique calmodulin gene of Aspergillus nidulans.
-
Characterization of 67 kD laminin receptor, a protein whose gene is overexpressed on treatment of cells with anti-benzo[a]pyrene-7,8-diol-9,10-epoxide.
-
Characterization of Ca2+/calmodulin-dependent protein kinase IV. Role in transcriptional regulation.
-
Characterization of Leu777Pro and Ile865Thr type IIA von Willebrand disease mutations.
-
Characterization of Mycobacterium montefiorense sp. nov., a novel pathogenic Mycobacterium from moray eels that is related to Mycobacterium triplex.
-
Characterization of a cDNA clone encoding human filaggrin and localization of the gene to chromosome region 1q21.
-
Characterization of a cDNA for the unexpressed form of cytochrome P-450g from the (-g) rat and differentiation of its mRNA from that of the (+g) phenotype using specific oligoprobes.
-
Characterization of a gene trap insertion into a novel gene, cordon-bleu, expressed in axial structures of the gastrulating mouse embryo.
-
Characterization of a genetically engineered elastin-like polypeptide for cartilaginous tissue repair.
-
Characterization of a male-predominant antisense transcript underexpressed in hybrids of Drosophila pseudoobscura and D. persimilis.
-
Characterization of a partial cDNA for lysyl hydroxylase from human skin fibroblasts; lysyl hydroxylase mRNAs are regulated differently by minoxidil derivatives and hydralazine.
-
Characterization of a protein cofactor that mediates protein kinase A regulation of the renal brush border membrane Na(+)-H+ exchanger.
-
Characterization of a putative insulin-responsive element and its binding protein(s) in rat angiotensinogen gene promoter: regulation by glucose and insulin.
-
Characterization of a zinc finger DNA-binding protein expressed specifically in Petunia petals and seedlings.
-
Characterization of alpha 2-macroglobulin binding to human trabecular meshwork cells: presence of the alpha 2-macroglobulin signaling receptor.
-
Characterization of an Epstein-Barr virus receptor on human epithelial cells.
-
Characterization of an acquired inhibitor to coagulation factor V. Antibody binding to the second C-type domain of factor V inhibits the binding of factor V to phosphatidylserine and neutralizes procoagulant activity.
-
Characterization of cDNA encoding mouse DNA repair protein O6-methylguanine-DNA methyltransferase and high-level expression of the wild-type and mutant proteins in Escherichia coli.
-
Characterization of elongation factor-1A (eEF1A-1) and eEF1A-2/S1 protein expression in normal and wasted mice.
-
Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line.
-
Characterization of functional and phenotypic changes in anti-Gag vaccine-induced T cell responses and their role in protection after HIV-1 infection.
-
Characterization of human Gadd45, a p53-regulated protein.
-
Characterization of human immunodeficiency virus type 1 in saliva and blood plasma by V3-specific heteroduplex tracking assay and genotype analyses.
-
Characterization of immunophilins in the silkmoth Bombyx mori.
-
Characterization of kinectin, a kinesin-binding protein: primary sequence and N-terminal topogenic signal analysis.
-
Characterization of proteins that interact with the cell-cycle regulatory protein Ran/TC4.
-
Characterization of reaction intermediates of human excision repair nuclease.
-
Characterization of the 3' terminus of RNA isolated from vesicular stomatitis virus and from its defective interfering particles.
-
Characterization of the DNase I hypersensitive site 3' of the human beta globin gene domain.
-
Characterization of the G protein-coupled receptor kinase GRK4. Identification of four splice variants.
-
Characterization of the SarA virulence gene regulator of Staphylococcus aureus.
-
Characterization of the cysJIH regions of Salmonella typhimurium and Escherichia coli B. DNA sequences of cysI and cysH and a model for the siroheme-Fe4S4 active center of sulfite reductase hemoprotein based on amino acid homology with spinach nitrite reductase.
-
Characterization of the flavoprotein moieties of NADPH-sulfite reductase from Salmonella typhimurium and Escherichia coli. Physicochemical and catalytic properties, amino acid sequence deduced from DNA sequence of cysJ, and comparison with NADPH-cytochrome P-450 reductase.
-
Characterization of the human Snrpn minimal promoter and cis elements within it.
-
Characterization of the interleukin 1 receptor-associated kinase 4 (IRAK4)-encoding gene in salmonid fish: the functional copy is rearranged in Oncorhynchus mykiss and that factor can impair TLR signaling in mammalian cells.
-
Characterization of the mouse FTZ-F1 gene, which encodes a key regulator of steroid hydroxylase gene expression.
-
Characterization of the mouse SPARC/osteonectin gene. Intron/exon organization and an unusual promoter region.
-
Characterization of the mouse transforming growth factor alpha gene: its expression during eyelid development and in waved 1 tissues.
-
Characterization of the multiple transferable resistance repressor, MtrR, from Neisseria gonorrhoeae.
-
Characterization of the porcine ATM gene: towards the generation of a novel non-murine animal model for Ataxia-Telangiectasia.
-
Characterization of the rat type III hexokinase gene promoter. A functional octamer 1 motif is critical for basal promoter activity.
-
Characterization of the recalcitrant CYP1 phenotype found in Atlantic killifish (Fundulus heteroclitus) inhabiting a Superfund site on the Elizabeth River, VA.
-
Characterization of the statin-like S1 and rat elongation factor 1 alpha as two distinctly expressed messages in rat.
-
Characterization of the variable-number tandem repeats in vrrA from different Bacillus anthracis isolates.
-
Characterizing Watson-Crick versus Hoogsteen Base Pairing in a DNA-Protein Complex Using Nuclear Magnetic Resonance and Site-Specifically 13C- and 15N-Labeled DNA.
-
Characterizing complex dynamics in the transactivation response element apical loop and motional correlations with the bulge by NMR, molecular dynamics, and mutagenesis.
-
Chemical characterization of DNA-immobilized InAs surfaces using X-ray photoelectron spectroscopy and near-edge X-ray absorption fine structure.
-
Chemical functionalization of oligodeoxynucleotides with multiple boronic acids for the polyvalent binding of saccharides.
-
Chemical rescue, multiple ionizable groups, and general acid-base catalysis in the HDV genomic ribozyme.
-
Chicken calmodulin genes. A species comparison of cDNA sequences and isolation of a genomic clone.
-
Chicken calmodulin promoter activity in proliferating and differentiated cells.
-
Chicken perinatal troponin Ts are generated by a combination of novel and phylogenetically conserved alternative splicing pathways.
-
Chromatin conformation of yeast centromeres
-
Chromium(VI) treatment of normal human lung cells results in guanine-specific DNA polymerase arrest, DNA-DNA cross-links and S-phase blockade of cell cycle.
-
Chromosomal localization of gene for human glutamate receptor subunit-7.
-
Chromosomal localization of human glutamate receptor genes.
-
Chromosomal localization of the mouse Src-like adapter protein (Slap) gene and its putative human homolog SLA.
-
Chromosomal rearrangements accompanying yeast mating-type switching: evidence for a gene-conversion model.
-
Chromosomal translocation in a human leukemic stem-cell line disrupts the T-cell antigen receptor delta-chain diversity region and results in a previously unreported fusion transcript.
-
Chromosomally located gene fusions constructed in Acinetobacter sp. ADP1 for the detection of salicylate.
-
Chromosome fragility at GAA tracts in yeast depends on repeat orientation and requires mismatch repair.
-
Chromosome rearrangements and aneuploidy in yeast strains lacking both Tel1p and Mec1p reflect deficiencies in two different mechanisms.
-
Circular RNAs are abundant, conserved, and associated with ALU repeats.
-
Circular ribozymes generated in Escherichia coli using group I self-splicing permuted intron-exon sequences.
-
Circular transcripts of the testis-determining gene Sry in adult mouse testis.
-
Circular viral DNA and anomalous junction sequence in PBMC of HIV-infected individuals with no detectable plasma HIV RNA.
-
Circulating tumor cells in HER-2 positive metastatic breast cancer patients treated with trastuzumab and chemotherapy.
-
Cis- and trans-acting ribozymes from a human pathogen, hepatitis delta virus.
-
Class-level relationships in the phylum Cnidaria: evidence from mitochondrial genome structure.
-
Class-level relationships in the phylum Cnidaria: molecular and morphological evidence.
-
Classification and genetic characterization of pattern-forming Bacilli.
-
Cleavage of oligoribonucleotides by a ribozyme derived from the hepatitis delta virus RNA sequence.
-
Clinical application of whole-genome sequencing in patients with primary immunodeficiency.
-
Clonal expansion and decreased occurrence of peripheral blood gamma delta T cells of the V delta 2J delta 3 lineage in multiple sclerosis patients.
-
Cloned Erwinia chrysanthemi out genes enable Escherichia coli to selectively secrete a diverse family of heterologous proteins to its milieu.
-
Cloning and analysis of microRNAs encoded by the primate gamma-herpesvirus rhesus monkey rhadinovirus.
-
Cloning and characterization of ATRAP, a novel protein that interacts with the angiotensin II type 1 receptor.
-
Cloning and characterization of DNA sequences surrounding the human gamma-, delta-, and beta-globin genes.
-
Cloning and characterization of PDE7B, a cAMP-specific phosphodiesterase.
-
Cloning and characterization of a cAMP-specific cyclic nucleotide phosphodiesterase.
-
Cloning and characterization of a cAMP-specific phosphodiesterase (TbPDE2B) from Trypanosoma brucei.
-
Cloning and characterization of a mammalian lithium-sensitive bisphosphate 3'-nucleotidase inhibited by inositol 1,4-bisphosphate.
-
Cloning and characterization of a novel endothelial promoter of the human CYP19 (aromatase P450) gene that is up-regulated in breast cancer tissue.
-
Cloning and characterization of developmental endothelial locus-1: an embryonic endothelial cell protein that binds the alphavbeta3 integrin receptor.
-
Cloning and characterization of rat-brain-specific transcripts: rare, brain-specific transcripts and tyrosine hydroxylase.
-
Cloning and characterization of the 5' end (exon 1) of the gene encoding human factor X.
-
Cloning and characterization of the major promoter of the human protein kinase C beta gene. Regulation by phorbol esters.
-
Cloning and characterization of three new murine genes encoding short homologues of RNase P RNA.
-
Cloning and characterization of two yeast genes encoding members of the CCCH class of zinc finger proteins: zinc finger-mediated impairment of cell growth.
-
Cloning and developmental expression of the chick type II and type III TGF beta receptors.
-
Cloning and expression of a human kidney cDNA for an alpha 2-adrenergic receptor subtype.
-
Cloning and expression of a novel Na(+)-dependent neutral amino acid transporter structurally related to mammalian Na+/glutamate cotransporters.
-
Cloning and expression of a novel, truncated, progesterone receptor.
-
Cloning and expression of full-length cDNA encoding human vitamin D receptor.
-
Cloning and sequence analysis of the human beta 1-adrenergic receptor 5'-flanking promoter region.
-
Cloning and sequencing of V genes from anti-osteosarcoma monoclonal antibodies TP-1 and TP-3: location of lysine residues and implications for radiolabeling.
-
Cloning and structural analysis of the human c-kit gene.
-
Cloning of a cDNA encoding bovine erythropoietin and analysis of its transcription in selected tissues.
-
Cloning of a complementary DNA encoding a new mouse B lymphocyte differentiation antigen, homologous to the human B1 (CD20) antigen, and localization of the gene to chromosome 19.
-
Cloning of an aquaporin homologue present in water channel containing endosomes of toad urinary bladder.
-
Cloning of cDNA and analysis of the gene for mouse angiotensin II type 2 receptor.
-
Cloning of human and mouse brain cDNAs coding for S1, the second member of the mammalian elongation factor-1 alpha gene family: analysis of a possible evolutionary pathway.
-
Cloning of human androgen receptor complementary DNA and localization to the X chromosome.
-
Cloning of rat thymic stromal lymphopoietin receptor (TSLPR) and characterization of genomic structure of murine Tslpr gene.
-
Cloning of the cDNA for the human beta 1-adrenergic receptor.
-
Cloning of the gene and cDNA for mammalian beta-adrenergic receptor and homology with rhodopsin.
-
Cloning of the gene encoding Leishmania donovani S-adenosylhomocysteine hydrolase, a potential target for antiparasitic chemotherapy.
-
Cloning of the mast cell protease, RMCP II. Evidence for cell-specific expression and a multi-gene family.
-
Cloning of the promoter region of human endoglin, the target gene for hereditary hemorrhagic telangiectasia type 1.
-
Cloning of the terminal loop of vaccinia virus DNA.
-
Cloning of zebrafish vsx1: expression of a paired-like homeobox gene during CNS development.
-
Cloning the Cryptococcus neoformans TRP1 gene by complementation in Saccharomyces cerevisiae.
-
Cloning, characterization, and chromosomal localization of rec1.3, a member of the G-protein-coupled receptor family highly expressed in brain.
-
Cloning, characterization, and expression of two angiotensin receptor (AT-1) isoforms from the mouse genome.
-
Cloning, characterization, and genetic mapping of the rat type 2 angiotensin II receptor gene.
-
Cloning, expression, and cellular localization of a human prenylcysteine lyase.
-
Cloning, expression, and chromosomal localization of beta-adrenergic receptor kinase 2. A new member of the receptor kinase family.
-
Cloning, heterologous expression, and chromosomal localization of human inositol polyphosphate 1-phosphatase.
-
Cloning, overexpression, purification, and immunobiology of an 85-kilodalton outer membrane protein from Haemophilus ducreyi.
-
Cloning, sequencing, and expression of the gene coding for the human platelet alpha 2-adrenergic receptor.
-
Cloning, sequencing, and recombinant expression of the porcine inhibitor of carbonic anhydrase: a novel member of the transferrin family.
-
Clostridium taeniosporum spore ribbon-like appendage structure, composition and genes.
-
Co-amplification of a novel cyclophilin-like gene (PPIE) with L-myc in small cell lung cancer cell lines.
-
Cobalamin inhibition of HIV-1 integrase and integration of HIV-1 DNA into cellular DNA.
-
Colocalization of BMP 7 and BMP 2 RNAs suggests that these factors cooperatively mediate tissue interactions during murine development.
-
Combinatorial expression of TRPV channel proteins defines their sensory functions and subcellular localization in C. elegans neurons.
-
Combinatorial mutagenesis of the reactive site region in plasminogen activator inhibitor I.
-
Combined EGFR/MET or EGFR/HSP90 inhibition is effective in the treatment of lung cancers codriven by mutant EGFR containing T790M and MET.
-
Combined effects of the p53 codon 72 and p73 G4C14-to-A4T14 polymorphisms on the risk of HPV16-associated oral cancer in never-smokers.
-
Common MFRP sequence variants are not associated with moderate to high hyperopia, isolated microphthalmia, and high myopia.
-
Common estrogen receptor polymorphism augments effects of hormone replacement therapy on E-selectin but not C-reactive protein.
-
Common non-synonymous polymorphisms in the BRCA1 Associated RING Domain (BARD1) gene are associated with breast cancer susceptibility: a case-control analysis.
-
Compact organization of rRNA genes in the filamentous fungus Ashbya gossypii.
-
Comparative analysis of the HTLV-I Rex and HIV-1 Rev trans-regulatory proteins and their RNA response elements.
-
Comparative analysis of the zeta-crystallin/quinone reductase gene in guinea pig and mouse.
-
Comparative analysis of type 2b von Willebrand disease mutations: implications for the mechanism of von Willebrand factor binding to platelets.
-
Comparative gene genealogical analyses of strains of serotype AD identify recombination in populations of serotypes A and D in the human pathogenic yeast Cryptococcus neoformans.
-
Comparative genomics applied to Mucor species with different lifestyles.
-
Comparative genomics of Mortierella elongata and its bacterial endosymbiont Mycoavidus cysteinexigens.
-
Comparative population structure of two deep-sea hydrothermal-vent-associated decapods (Chorocaris sp. 2 and Munidopsis lauensis) from southwestern Pacific back-arc basins.
-
Comparative studies on the secondary structure of ovalbumin messenger RNA and its complementary DNA transcript.
-
Comparative tests of evolutionary trade-offs in a palinurid lobster acoustic system.
-
Comparing human pancreatic cell secretomes by in vitro aptamer selection identifies cyclophilin B as a candidate pancreatic cancer biomarker.
-
Comparison of 5.8S ribosomal DNA sequences among the basidiomycetous yeast genera Cystofilobasidium, Filobasidium and Filobasidiella.
-
Comparison of direct and indirect methods of carrier detection in an X-linked disease.
-
Comparison of human and Xenopus GATA-2 promoters.
-
Comparison of myristoyl-CoA:protein N-myristoyltransferases from three pathogenic fungi: Cryptococcus neoformans, Histoplasma capsulatum, and Candida albicans.
-
Comparison of ribosomal DNA ITS regions among geographic isolates of Cenococcum geophilum.
-
Comparison of the evolutionary dynamics of symbiotic and housekeeping loci: a case for the genetic coherence of rhizobial lineages.
-
Comparison of the roles of calcineurin in physiology and virulence in serotype D and serotype A strains of Cryptococcus neoformans.
-
Comparison of use of phenotypic and genotypic characteristics for identification of species of the anamorph genus Candida and related teleomorph yeast species.
-
Comparison of viral Env proteins from acute and chronic infections with subtype C human immunodeficiency virus type 1 identifies differences in glycosylation and CCR5 utilization and suggests a new strategy for immunogen design.
-
Complementary techniques: RNA amplification for gene profiling analysis.
-
Complete genomic nucleotide sequence of the temperate bacteriophage Aa Phi 23 of Actinobacillus actinomycetemcomitans.
-
Complete sequence of a gene encoding a human type I keratin: sequences homologous to enhancer elements in the regulatory region of the gene.
-
Complete sequence of the Drosophila nonmuscle myosin heavy-chain transcript: conserved sequences in the myosin tail and differential splicing in the 5' untranslated sequence.
-
Complex regulation of human c-kit transcription by promoter repressors, activators, and specific myb elements.
-
Complexity of cytoplasmic polyadenylated and nonpolyadenylated rat brain ribonucleic acids.
-
Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer.
-
Comprehensive identification of mRNA isoforms reveals the diversity of neural cell-surface molecules with roles in retinal development and disease.
-
Comprehensive molecular diagnosis of 179 Leber congenital amaurosis and juvenile retinitis pigmentosa patients by targeted next generation sequencing.
-
Computational tools for understanding sequence variability in recombination signals.
-
Conformational studies of the nucleic acid binding sites for Xenopus transcription factor IIIA.
-
Consensus and ancestral state HIV vaccines.
-
Consensus and variant cAMP-regulated enhancers have distinct CREB-binding properties.
-
Consensus multi-locus sequence typing scheme for Cryptococcus neoformans and Cryptococcus gattii.
-
Conservation of Endo16 expression in sea urchins despite evolutionary divergence in both cis and trans-acting components of transcriptional regulation.
-
Conservation of structure and location of Rhizobium meliloti and Klebsiella pneumoniae nifB genes.
-
Conservation of the 3' terminal nucleotide sequences of Ebola and Marburg virus.
-
Conserved sequence and structural elements in the HIV-1 principal neutralizing determinant: corrections and clarifications.
-
Constitutive expression of CaSRP1, a hot pepper small rubber particle protein homolog, resulted in fast growth and improved drought tolerance in transgenic Arabidopsis plants.
-
Constructing atomic-resolution RNA structural ensembles using MD and motionally decoupled NMR RDCs.
-
Construction of new ligand binding sites in proteins of known structure. II. Grafting of a buried transition metal binding site into Escherichia coli thioredoxin.
-
Contamination with E1A-positive wild-type adenovirus accounts for species-specific stimulation of islet cell proliferation by CCK: a cautionary note.
-
Contractile proteins in Drosophila development.
-
Contrasting Roles of Transcription Factors Spineless and EcR in the Highly Dynamic Chromatin Landscape of Butterfly Wing Metamorphosis.
-
Contrasting quaternary histories in an ecologically divergent sister pair of low-dispersing intertidal fish (Xiphister) revealed by multilocus DNA analysis.
-
Contribution of RPB2 to multilocus phylogenetic studies of the euascomycetes (Pezizomycotina, Fungi) with special emphasis on the lichen-forming Acarosporaceae and evolution of polyspory.
-
Contribution of a 28-kilodalton membrane protein to the virulence of Haemophilus influenzae.
-
Control of meiotic recombination and gene expression in yeast by a simple repetitive DNA sequence that excludes nucleosomes.
-
Control of yeast mating signal transduction by a mammalian beta 2-adrenergic receptor and Gs alpha subunit.
-
Convergent evolution of a complex fruit structure in the tribe Brassiceae (Brassicaceae).
-
Cooperation among multiple transcription factors is required for access to minimal T-cell receptor alpha-enhancer chromatin in vivo.
-
Cooperation between core binding factor and adjacent promoter elements contributes to the tissue-specific expression of interleukin-3.
-
Cooperation between somatic mutation and germline-encoded residues enables antibody recognition of HIV-1 envelope glycans.
-
Cooperation between the Hepatitis C Virus p7 and NS5B Proteins Enhances Virion Infectivity.
-
Cooperation between transcription factor AP-1 and NF-kappaB in the induction of interleukin-8 in human pancreatic adenocarcinoma cells by hypoxia.
-
Coordinated activation of candidate proto-oncogenes and cancer testes antigens via promoter demethylation in head and neck cancer and lung cancer.
-
Copper-dependent site-specific mutagenesis by benzoyl peroxide in the supF gene of the mutation reporter plasmid pS189.
-
Core sequences and a cleavage site wobble pair required for HDV antigenomic ribozyme self-cleavage.
-
Core-associated non-duplex sequences distinguishing the genomic and antigenomic self-cleaving RNAs of hepatitis delta virus.
-
Correct splicing despite mutation of the invariant first nucleotide of a 5' splice site: a possible basis for disparate clinical phenotypes in siblings with adenosine deaminase deficiency.
-
Correction of dystrophin expression in cells from Duchenne muscular dystrophy patients through genomic excision of exon 51 by zinc finger nucleases.
-
Correlation of doxorubicin footprints with deletion endpoints in lacO of E. coli.
-
Cosmids map two incontinentia pigmenti type 1 (IP1) translocation breakpoints to a 180-kb region within a 1.2-Mb YAC contig.
-
Coupled mutagenesis screens and genetic mapping in zebrafish.
-
CovR activation of the dipeptide permease promoter (PdppA) in Group A Streptococcus.
-
Cowpox virus contains two copies of an early gene encoding a soluble secreted form of the type II TNF receptor.
-
Cowpox virus genome encodes a second soluble homologue of cellular TNF receptors, distinct from CrmB, that binds TNF but not LT alpha.
-
Creation of an active estrogen-responsive element by a single base change in the flanking sequence of a cellular oncogene: a possible mechanism for hormonal carcinogenesis?
-
Critical factors in basal cell adhesion molecule/lutheran-mediated adhesion to laminin.
-
Cross-sectional detection of acute HIV infection: timing of transmission, inflammation and antiretroviral therapy.
-
Cryptococcus neoformans shows a remarkable genotypic diversity in Brazil.
-
Cryptococcus neoformans virulence gene discovery through insertional mutagenesis.
-
Crystal structure and sequence-dependent conformation of the A.G mispaired oligonucleotide d(CGCAAGCTGGCG).
-
Crystal structure of LacI member, PurR, bound to DNA: minor groove binding by alpha helices.
-
Crystal structure of the human LRH-1 DBD-DNA complex reveals Ftz-F1 domain positioning is required for receptor activity.
-
Crystal structure of the lactose operon repressor and its complexes with DNA and inducer.
-
Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding.
-
Crystallization and initial X-ray crystallographic characterization of recombinant bovine inositol polyphosphate 1-phosphatase produced in Spodoptera frugiperda cells.
-
Crystallization and preliminary X-ray analysis of an Escherichia coli purine repressor-hypoxanthine-DNA complex.
-
Crystallization and preliminary crystallographic studies of the decadeoxyoligonucleotide d(CpGpTpApCpGpTpApCpG).
-
Cultured human trabecular meshwork cells express aquaporin-1 water channels.
-
Cutting of M13mp7 phage DNA and excision of cloned single-stranded sequences by restriction endonucleases.
-
Cysteine-rich regions of pig gastric mucin contain von willebrand factor and cystine knot domains at the carboxyl terminal(1).
-
Cystic fibrosis transmembrane regulator regulates uptake of sphingoid base phosphates and lysophosphatidic acid: modulation of cellular activity of sphingosine 1-phosphate.
-
Cytochrome P1-450 structural gene in mouse, rat, and rabbit: differences in DNA methylation and developmental expression of mRNA.
-
Cytochrome P450IIIA activity and cytokine-mediated synthesis of nitric oxide.
-
Cytokine mRNA expression in postischemic/reperfused myocardium.
-
Cytokine production induced by Mycobacterium tuberculosis lipoarabinomannan. Relationship to chemical structure.
-
Cytokine transcriptional events during helper T cell subset differentiation.
-
Cytokine-mediated production of nitric oxide in isolated rat hepatocytes is dependent on cytochrome P-450III activity.
-
Cytoplasmic domain truncation enhances fusion activity by the exterior glycoprotein complex of human immunodeficiency virus type 2 in selected cell types.
-
Cytoplasmic dynein is required to oppose the force that moves nuclei towards the hyphal tip in the filamentous ascomycete Ashbya gossypii.
-
Cytosine deamination in mismatched base pairs.
-
Cytoskeletal actin gene families of Xenopus borealis and Xenopus laevis.
-
Cytosolic hydroxymethyldihydropterin pyrophosphokinase/dihydropteroate synthase from Arabidopsis thaliana: a specific role in early development and stress response.
-
DART-seq: an antibody-free method for global m6A detection.
-
DNA CpG methylation inhibits binding of NF-kappa B proteins to the HIV-1 long terminal repeat cognate DNA motifs.
-
DNA Sequence Constraints Define Functionally Active Steroid Nuclear Receptor Binding Sites in Chromatin.
-
DNA array-based gene profiling in tumor immunology.
-
DNA base modification: ionized base pairs and mutagenesis.
-
DNA bending near the replication origin of IncFII plasmid NR1.
-
DNA determinants important in sequence recognition by Eco RI endonuclease.
-
DNA mismatch correction in a defined system.
-
DNA mismatch correction.
-
DNA nanotubes self-assembled from triple-crossover tiles as templates for conductive nanowires.
-
DNA polymerase arrest by adducted trivalent chromium.
-
DNA polymerase zeta introduces multiple mutations when bypassing spontaneous DNA damage in Saccharomyces cerevisiae.
-
DNA polymerase zeta is essential for hexavalent chromium-induced mutagenesis.
-
DNA sequence analysis and restriction fragment length polymorphism (RFLP) typing of the HLA-DQw2 alleles associated with dermatitis herpetiformis.
-
DNA sequence analysis of X-ray induced Adh null mutations in Drosophila melanogaster.
-
DNA sequence and genetic characterization of plasmid pFQ11 from Frankia alni strain CpI1.
-
DNA sequence characterization and molecular evolution of MAT1 and MAT2 mating-type loci of the self-compatible ascomycete mold Neosartorya fischeri.
-
DNA sequence patents are not in the grave yet.
-
DNA sequence specificity of doxorubicin-induced mutational damage in uvrB- Escherichia coli.
-
DNA sequences of structural genes for Eco RI DNA restriction and modification enzymes.
-
DNA strand breakage by wheat germ type 1 topoisomerase.
-
DNA- and PCR-fingerprinting in fungi.
-
DNA-XPA interactions: a (31)P NMR and molecular modeling study of dCCAATAACC association with the minimal DNA-binding domain (M98-F219) of the nucleotide excision repair protein XPA.
-
DNA-based animal models of human disease: from genotype to phenotype.
-
DNA-binding protein RAP1 stimulates meiotic recombination at the HIS4 locus in yeast.
-
DNA-dependent activation of the hMutSalpha ATPase.
-
DO-RIP-seq to quantify RNA binding sites transcriptome-wide.
-
DRAGON: a member of the repulsive guidance molecule-related family of neuronal- and muscle-expressed membrane proteins is regulated by DRG11 and has neuronal adhesive properties.
-
DSG2 mutations contribute to arrhythmogenic right ventricular dysplasia/cardiomyopathy.
-
DVR-4 (bone morphogenetic protein-4) as a posterior-ventralizing factor in Xenopus mesoderm induction.
-
De Novo SOX6 Variants Cause a Neurodevelopmental Syndrome Associated with ADHD, Craniosynostosis, and Osteochondromas.
-
De novo assembly using low-coverage short read sequence data from the rice pathogen Pseudomonas syringae pv. oryzae.
-
De novo design, expression, and characterization of Felix: a four-helix bundle protein of native-like sequence.
-
De novo variants in the alternative exon 5 of SCN8A cause epileptic encephalopathy.
-
Decay of mutualistic potential in aphid endosymbionts through silencing of biosynthetic loci: Buchnera of Diuraphis.
-
Decoy mRNAs reduce beta-amyloid precursor protein mRNA in neuronal cells.
-
Deep divergence and rapid evolutionary rates in gut-associated Acetobacteraceae of ants.
-
Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs.
-
Deep-coverage whole genome sequences and blood lipids among 16,324 individuals.
-
Defective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiency.
-
Deletion analysis of bacteriophage T4 tertiary origins. A promoter sequence is required for a rifampicin-resistant replication origin.
-
Deletion analysis of recombinant human factor V. Evidence for a phosphatidylserine binding site in the second C-type domain.
-
Deletion of CFHR3 and CFHR1 genes in age-related macular degeneration.
-
Deletion of V335 from the L2 domain of the insulin receptor results in a conformationally abnormal receptor that is unable to bind insulin and causes Donohue's syndrome in a human subject.
-
Deletion of Y chromosome sequences located outside the testis determining region can cause XY female sex reversal.
-
Deletion of azoospermia factor a (AZFa) region of human Y chromosome caused by recombination between HERV15 proviruses.
-
Deletion of carboxy-terminal residues of murine granulocyte-macrophage colony-stimulating factor results in a loss of biologic activity and altered glycosylation.
-
Deletion of p16 and p15 genes in brain tumors.
-
Deletion of the carboxyl terminus of Tie2 enhances kinase activity, signaling, and function. Evidence for an autoinhibitory mechanism.
-
Deletion-mutant epidermal growth factor receptor in human gliomas: effects of type II mutation on receptor function.
-
Deletions of a DNA sequence in retinoblastomas and mesenchymal tumors: organization of the sequence and its encoded protein.
-
Delineation of the intronless nature of the genes for the human and hamster beta 2-adrenergic receptor and their putative promoter regions.
-
Demonstration that mutation of the type II transforming growth factor beta receptor inactivates its tumor suppressor activity in replication error-positive colon carcinoma cells.
-
Dendritic cells pulsed with RNA are potent antigen-presenting cells in vitro and in vivo.
-
Depletion of casein kinase II by antisense oligonucleotide prevents neuritogenesis in neuroblastoma cells.
-
Depletion of catalytic and regulatory subunits of protein kinase CK2 by antisense oligonucleotide treatment of neuroblastoma cells.
-
Derivation of a biologically contained replication system for human immunodeficiency virus type 1.
-
Desensitization, internalization, and signaling functions of beta-arrestins demonstrated by RNA interference.
-
Design and Analysis of Localized DNA Hybridization Chain Reactions
-
Design of thermally responsive, recombinant polypeptide carriers for targeted drug delivery.
-
Detection of circulating prostate specific antigen expressing prostatic cells in the bone marrow of radical prostatectomy patients by sensitive reverse transcriptase polymerase chain reaction.
-
Detection of frequent allelic loss on proximal chromosome 17q in sporadic breast carcinoma using microsatellite length polymorphisms.
-
Detection of human immunodeficiency virus type 1 DNA sequence using plasmonics nanoprobes.
-
Detection of mutations by cleavage of DNA heteroduplexes with bacteriophage resolvases.
-
Determinants of CD4 independence for a human immunodeficiency virus type 1 variant map outside regions required for coreceptor specificity.
-
Determination of aromatase cytochrome P450 messenger ribonucleic acid in human breast tissue by competitive polymerase chain reaction amplification.
-
Determination of estrogen receptor messenger ribonucleic acid (mRNA) and cytochrome P450 aromatase mRNA levels in adipocytes and adipose stromal cells by competitive polymerase chain reaction amplification.
-
Determination of the primary structures of human skin chymase and cathepsin G from cutaneous mast cells of urticaria pigmentosa lesions.
-
Determining centromere identity: cyclical stories and forking paths.
-
Development and application of a phylogenomic toolkit: resolving the evolutionary history of Madagascar's lemurs.
-
Development and characterization of an Fv-1-sensitive retrovirus-packaging system: single-hit titration kinetics observed in restrictive cells.
-
Development of CRISPR as an Antiviral Strategy to Combat SARS-CoV-2 and Influenza.
-
Development of Saccharomyces cerevisiae as a model pathogen. A system for the genetic identification of gene products required for survival in the mammalian host environment.
-
Development of resistance mutations in women receiving standard antiretroviral therapy who received intrapartum nevirapine to prevent perinatal human immunodeficiency virus type 1 transmission: a substudy of pediatric AIDS clinical trials group protocol 316.
-
Developmental and spatial patterns of expression of the mouse homeobox gene, Hox 2.1.
-
Developmental expression of glycogenolytic enzymes in rabbit tissues: possible relationship to fetal lung maturation.
-
Developmental regulation of VDJ recombination by the core fragment of the T cell receptor alpha enhancer.
-
Developmental regulation of cytochrome oxidase subunit VIa isoforms in cardiac and skeletal muscle.
-
Developmental regulation of mouse SPARC (osteonectin) gene expression.
-
Diagnosis of mitochondrial trifunctional protein deficiency in a blood spot from the newborn screening card by tandem mass spectrometry and DNA analysis.
-
Dicistronic polioviruses as expression vectors for foreign genes.
-
Differences in (G+C) content between species: a commentary on Forsdyke's "chromosomal viewpoint" of speciation.
-
Differences in V kappa gene utilization and VH CDR3 sequence among anti-DNA from C3H-lpr mice and lupus mice with nephritis.
-
Differences in mRNA expression patterns between patellar tendons and anterior cruciate ligaments of immature pigs.
-
Differences in the regulation of messenger RNA for housekeeping and specialized-cell ferritin. A comparison of three distinct ferritin complementary DNAs, the corresponding subunits, and identification of the first processed in amphibia.
-
Different G protein-coupled receptor kinases govern G protein and beta-arrestin-mediated signaling of V2 vasopressin receptor.
-
Different dimerization activities of alpha and beta thyroid hormone receptor isoforms.
-
Different evolutionary pathways of HIV-1 between fetus and mother perinatal transmission pairs indicate unique immune selection in fetuses.
-
Different methods of sample preparation influence sensitivity of Mycobacterium tuberculosis and Borrelia burgdorferi PCR.
-
Different spectra of genomic deletions within the CCM genes between Italian and American CCM patient cohorts.
-
Differential desensitization and phosphorylation of three cloned and transfected alpha 2-adrenergic receptor subtypes.
-
Differential display of hepatic mRNA from killifish (Fundulus heteroclitus) inhabiting a Superfund estuary.
-
Differential effects of overexpressed glucokinase and hexokinase I in isolated islets. Evidence for functional segregation of the high and low Km enzymes.
-
Differential effects of prostate cancer therapeutics on neuroendocrine transdifferentiation.
-
Differential expression and regulation of the glucokinase gene in liver and islets of Langerhans.
-
Differential expression of gamma-aminobutyric acidA receptor subunits.
-
Differential expression of p63 isoforms in female reproductive organs.
-
Differential gene expression from a single transcription unit during spermatogenesis.
-
Differential gene expression patterns in HER2/neu-positive and -negative breast cancer cell lines and tissues.
-
Differential inactivation of CDKN2 and Rb protein in non-small-cell and small-cell lung cancer cell lines.
-
Differential induction of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase genes in Arabidopsis thaliana by wounding and pathogenic attack.
-
Differential induction of mRNAs for the glycolytic and ethanolic fermentative pathways by hypoxia and anoxia in maize seedlings.
-
Differential localization of allograft nitric oxide synthesis: comparison of liver and heart transplantation in the rat model.
-
Differential modulation of Th1- and Th2-related cytokine mRNA expression by a synthetic peptide homologous to a conserved domain within retroviral envelope protein.
-
Differential molecular mechanism of the estrogen action that regulates lactoferrin gene in human and mouse.
-
Differential patterns of male and female mtDNA exchange across the Atlantic Ocean in the blue mussel, Mytilus edulis.
-
Differential regulation of estrogen receptor alpha, glucocorticoid receptor and retinoic acid receptor alpha transcriptional activity by melatonin is mediated via different G proteins.
-
Differential regulation of genes by retrotransposons in rice promoters.
-
Differential regulation of vascular cell adhesion molecule 1 gene expression by specific NF-kappa B subunits in endothelial and epithelial cells.
-
Differential requirement for STAT by gain-of-function and wild-type receptor tyrosine kinase Torso in Drosophila.
-
Differential transcriptional activation of peroxisome proliferator-activated receptor gamma by omega-3 and omega-6 fatty acids in MCF-7 cells.
-
Differentially labeled mutant oligonucleotides for analysis of protein-DNA interactions.
-
Differentiation of strains in Mycobacterium tuberculosis complex by DNA sequence polymorphisms, including rapid identification of M. bovis BCG.
-
Digital image analysis for rapid quantification of total RNA and cDNA for SMART-PCR.
-
Dimerization of NF-KB2 with RelA(p65) regulates DNA binding, transcriptional activation, and inhibition by an I kappa B-alpha (MAD-3).
-
Diminished capacity for p53 in mediating a radiation-induced G1 arrest in established human tumor cell lines.
-
Dinucleotide polymorphism of p73 gene is associated with a reduced risk of lung cancer in a Chinese population.
-
Dinucleotide repeat polymorphism at the human erythropoietin receptor locus (EPOR) at 19p13.
-
Dinucleotide repeat polymorphisms at the SCN4A locus suggest allelic heterogeneity of hyperkalemic periodic paralysis and paramyotonia congenita.
-
Diploids in the Cryptococcus neoformans serotype A population homozygous for the alpha mating type originate via unisexual mating.
-
Direct PCR sequencing with boronated nucleotides.
-
Direct cloning of DNA sequences from the common fragile site region at chromosome band 3p14.2.
-
Direct interactions between autoantigen La and human immunodeficiency virus leader RNA.
-
Direct interactions between autoantigen La and human immunodeficiency virus leader RNA.
-
Direct regulation of beta3-integrin subunit gene expression by HOXA10 in endometrial cells.
-
Direct sequencing of the activation peptide and the catalytic domain of the factor IX gene in six species.
-
Directed enzyme pro-drug gene therapy for pancreatic cancer in vivo.
-
Directed nucleation assembly of DNA tile complexes for barcode-patterned lattices.
-
Disarming the mustard oil bomb.
-
Discovery of MLL1 binding units, their localization to CpG Islands, and their potential function in mitotic chromatin.
-
Discrete and complementary mechanisms of protection of beta-cells against cytokine-induced and oxidative damage achieved by bcl-2 overexpression and a cytokine selection strategy.
-
Discrete in vivo roles for the MutL homologs Mlh2p and Mlh3p in the removal of frameshift intermediates in budding yeast.
-
Discrimination of Mycobacterium tuberculosis strains by PCR.
-
Discrimination of tRNALeu isoacceptors by the insertion mutant of Escherichia coli leucyl-tRNA synthetase.
-
Disease-causing mutations in exon 11 of the medium-chain acyl-CoA dehydrogenase gene.
-
Disentangling the Collema-Leptogium complex through a molecular phylogenetic study of the Collemataceae (Peltigerales, lichen-forming Ascomycota).
-
Disparity in the kinetics of onset of hypermutation in immunoglobulin heavy and light chains.
-
Disproportionate relationship between APOBEC-1 expression and apolipoprotein B mRNA editing activity.
-
Disruption of PAX6 function in mice homozygous for the Pax6Sey-1Neu mutation produces abnormalities in the early development and regionalization of the diencephalon.
-
Disruption of a topoisomerase-DNA cleavage complex by a DNA helicase.
-
Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production.
-
Disruptive mRNA folding increases translational efficiency of catechol-O-methyltransferase variant.
-
Dissociation of bacteriophage T4 DNA polymerase and its processivity clamp after completion of Okazaki fragment synthesis.
-
Distinct combinations of NF-kappa B subunits determine the specificity of transcriptional activation.
-
Distinct effects in primary macrophages and lymphocytes of the human immunodeficiency virus type 1 accessory genes vpr, vpu, and nef: mutational analysis of a primary HIV-1 isolate.
-
Distinct functional properties of sodium channel variants are associated with usage of alternative exons in Nilaparvata lugens.
-
Distinct functions of two isoforms of a homeobox gene, BP1 and DLX7, in the regulation of the beta-globin gene.
-
Distinct mechanisms control the stability of the related S-phase cyclins Clb5 and Clb6.
-
Distinct nuclear proteins competing for an overlapping sequence of cyclic adenosine monophosphate and negative regulatory elements regulate tissue-specific mouse renin gene expression.
-
Distinct roles for c-Myb and core binding factor/polyoma enhancer-binding protein 2 in the assembly and function of a multiprotein complex on the TCR delta enhancer in vivo.
-
Distinct single amino acid replacements in the control of virulence regulator protein differentially impact streptococcal pathogenesis.
-
Distinguishing direct versus indirect transcription factor-DNA interactions.
-
Distribution and abundance of microsatellites in the yeast genome can Be explained by a balance between slippage events and point mutations.
-
Divergence dates for Malagasy lemurs estimated from multiple gene loci: geological and evolutionary context.
-
Diverse hypermutability of multiple expressed sequence motifs present in a cancer with microsatellite instability.
-
Diverse spermatogenic defects in humans caused by Y chromosome deletions encompassing a novel RNA-binding protein gene.
-
Diversification before the most recent glaciation in Balanus glandula.
-
Diversity and host range of foliar fungal endophytes: are tropical leaves biodiversity hotspots?
-
Diversity and organization of human T cell receptor delta variable gene segments.
-
Diversity considerations in HIV-1 vaccine selection.
-
Do clinical manifestations of resistance to thyroid hormone correlate with the functional alteration of the corresponding mutant thyroid hormone-beta receptors?
-
Does the aging skeletal muscle maintain its endocrine function?
-
Domain 3 of hepatitis C virus core protein is sufficient for intracellular lipid accumulation.
-
Domain organization of chicken gizzard myosin light chain kinase deduced from a cloned cDNA.
-
Domains of the adenovirus E1A protein required for oncogenic activity are also required for dissociation of E2F transcription factor complexes.
-
Dominant selection system for use in Cryptococcus neoformans.
-
Dr(a-) polymorphism of decay accelerating factor. Biochemical, functional, and molecular characterization and production of allele-specific transfectants.
-
Draft genome of the fungicidal biological control agent Burkholderia anthina strain XXVI.
-
Dramatic mitochondrial gene rearrangements in the hermit crab Pagurus longicarpus (Crustacea, anomura).
-
Droplet-based pyrosequencing using digital microfluidics.
-
Drosophila TFIID binds to a conserved downstream basal promoter element that is present in many TATA-box-deficient promoters.
-
Drosophila stretchin-MLCK is a novel member of the Titin/Myosin light chain kinase family.
-
Drosophila ultraspiracle modulates ecdysone receptor function via heterodimer formation.
-
Dual stem loops within the poliovirus internal ribosomal entry site control neurovirulence.
-
Dynamic functional evolution of an odorant receptor for sex-steroid-derived odors in primates.
-
Dynamic motions of the HIV-1 frameshift site RNA.
-
E1A-mediated inhibition of myogenesis correlates with a direct physical interaction of E1A12S and basic helix-loop-helix proteins.
-
E2F4-RB and E2F4-p107 complexes suppress gene expression by transforming growth factor beta through E2F binding sites.
-
ELAV proteins stabilize deadenylated intermediates in a novel in vitro mRNA deadenylation/degradation system.
-
ENU mutagenesis identifies mice with cardiac fibrosis and hepatic steatosis caused by a mutation in the mitochondrial trifunctional protein beta-subunit.
-
ENU mutagenesis identifies mice with mitochondrial branched-chain aminotransferase deficiency resembling human maple syrup urine disease.
-
EWS-FLI1 utilizes divergent chromatin remodeling mechanisms to directly activate or repress enhancer elements in Ewing sarcoma.
-
EZH2 RIP-seq Identifies Tissue-specific Long Non-coding RNAs.
-
Early specialization of the superfast myosin in extraocular and laryngeal muscles.
-
Ecdysone-inducible gene expression in mammalian cells and transgenic mice.
-
Echinomycin, a bis-intercalating agent, induces C-->T mutations via cytosine deamination.
-
Ecosystem rooting depth determined with caves and DNA.
-
Ecsit is required for Bmp signaling and mesoderm formation during mouse embryogenesis.
-
Ectomycorrhizal fungal community in a tropical forest dominated by the Neotropical Dipterocarp, Pakaraimea dipterocarpaceae
-
Ectopic expression of Hel-N1, an RNA-binding protein, increases glucose transporter (GLUT1) expression in 3T3-L1 adipocytes.
-
Ectopic expression of mucins in colorectal cancer metastasis.
-
Effect of RNA secondary structure on polyadenylation site selection.
-
Effect of bilirubin UDP glucuronosyltransferase 1 gene TATA box genotypes on serum bilirubin concentrations in chronic liver injuries.
-
Effect of estrogen on gene expression in the chick oviduct. Regulation of the ovomucoid gene.
-
Effect of isopropyl-beta-D-thiogalactopyranosid induction of the lac operon on the specificity of spontaneous and doxorubicin-induced mutations in Escherichia coli.
-
Effect of mutations in genes affecting homologous recombination on restriction enzyme-mediated and illegitimate recombination in Saccharomyces cerevisiae.
-
Effect of the laccase gene CNLAC1, on virulence of Cryptococcus neoformans.
-
Effect of vasoactive intestinal peptide (VIP) on cytokine production and expression of VIP receptors in thymocyte subsets.
-
Effective treatment of models of multiple sclerosis by matrix metalloproteinase inhibitors.
-
Effects of MDM2 promoter polymorphisms and p53 codon 72 polymorphism on risk and age at onset of squamous cell carcinoma of the head and neck.
-
Effects of chimeric mutants of human immunodeficiency virus type 1 Rev and human T-cell leukemia virus type I Rex on nucleolar targeting signals.
-
Effects of genital tract inflammation on human immunodeficiency virus type 1 V3 populations in blood and semen.
-
Effects of mutant Ran/TC4 proteins on cell cycle progression.
-
Effects of sequence variation on differential allelic transcription factor occupancy and gene expression.
-
Effects of the NIK aly mutation on NF-kappaB activation by the Epstein-Barr virus latent infection membrane protein, lymphotoxin beta receptor, and CD40.
-
Efficient Tor signaling requires a functional class C Vps protein complex in Saccharomyces cerevisiae.
-
Efficient and specific gene knockdown by small interfering RNAs produced in bacteria.
-
Efficient and specific repair of sickle beta-globin RNA by trans-splicing ribozymes.
-
Efficient polyadenylation within the human immunodeficiency virus type 1 long terminal repeat requires flanking U3-specific sequences.
-
Efficient processing of primary microRNA hairpins by Drosha requires flanking nonstructured RNA sequences.
-
Efficient purging of deleterious mutations in plants with haploid selfing.
-
Ehlers-Danlos syndrome type VI results from a nonsense mutation and a splice site-mediated exon-skipping mutation in the lysyl hydroxylase gene.
-
Ehrlichia chaffeensis, a new species associated with human ehrlichiosis.
-
Elevated MAL expression is accompanied by promoter hypomethylation and platinum resistance in epithelial ovarian cancer.
-
Elevated frequency of microsatellite mutations in TK6 human lymphoblast clones selected for mutations at the thymidine kinase locus.
-
Elevation of topoisomerase I messenger RNA, protein, and catalytic activity in human tumors: demonstration of tumor-type specificity and implications for cancer chemotherapy.
-
Elovl4 5-bp-deletion knock-in mice develop progressive photoreceptor degeneration.
-
Embryonic expression of Lim-1, the mouse homolog of Xenopus Xlim-1, suggests a role in lateral mesoderm differentiation and neurogenesis.
-
Embryonic expression of mouse bone morphogenetic protein-1 (BMP-1), which is related to the Drosophila dorsoventral gene tolloid and encodes a putative astacin metalloendopeptidase.
-
Embryonic expression patterns of the neural cell adhesion molecule gene are regulated by homeodomain binding sites.
-
Emergence of the keratinocyte growth factor multigene family during the great ape radiation.
-
Endocarditis in a dog due to infection with a novel Bartonella subspecies.
-
Endoglin, a TGF-beta binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1.
-
Endoglin, an ancillary TGFbeta receptor, is required for extraembryonic angiogenesis and plays a key role in heart development.
-
Endoplasmic reticulum chaperone GRP94 subunit assembly is regulated through a defined oligomerization domain.
-
Endosymbiont gene functions impaired and rescued by polymerase infidelity at poly(A) tracts.
-
Endothelin-3 frameshift mutation in congenital central hypoventilation syndrome.
-
Energetic contribution of non-essential 5' sequence to catalysis in a hepatitis delta virus ribozyme.
-
Engineering an analog-sensitive CDK12 cell line using CRISPR/Cas.
-
Engineering synthetic TALE and CRISPR/Cas9 transcription factors for regulating gene expression.
-
Engraftment of gene-modified umbilical cord blood cells in neonates with adenosine deaminase deficiency.
-
Enhanced expression of interleukin-3 and granulocyte-macrophage colony-stimulating factor receptor subunits in murine hematopoietic cells stimulated with hematopoietic growth factors.
-
Enhancement of hypoxia-induced tumor cell death in vitro and radiation therapy in vivo by use of small interfering RNA targeted to hypoxia-inducible factor-1alpha.
-
Enhancer analysis of the mouse HNF-3 beta gene: regulatory elements for node/notochord and floor plate are independent and consist of multiple sub-elements.
-
Enhancer-dependent and -independent steps in the rearrangement of a human T cell receptor delta transgene.
-
Enhancing RNA repair efficiency by combining trans-splicing ribozymes that recognize different accessible sites on a target RNA.
-
Epidermal growth factor receptor cooperates with signal transducer and activator of transcription 3 to induce epithelial-mesenchymal transition in cancer cells via up-regulation of TWIST gene expression.
-
Epidermal growth factor replaces estrogen in the stimulation of female genital-tract growth and differentiation.
-
Epigenetic alterations in cytochrome P450 oxidoreductase (Por) in sperm of rats exposed to tetrahydrocannabinol (THC).
-
Epigenetic basis of oncogenic-Kras-mediated epithelial-cellular proliferation and plasticity.
-
Epigenetic silencing of Kruppel like factor-3 increases expression of pro-metastatic miR-182.
-
Epithelial invasion by Escherichia coli bearing Dr fimbriae is controlled by nitric oxide-regulated expression of CD55.
-
Epitope tagging for tracking elastin-like polypeptides.
-
Equatorial segment protein defines a discrete acrosomal subcompartment persisting throughout acrosomal biogenesis.
-
Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase.
-
Erythroid AP-1/NF-E2 elements vary in their response to NF-E2.
-
Erythroid transcription factor NF-E2 coordinates hemoglobin synthesis.
-
Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein.
-
Essential light chain of Drosophila nonmuscle myosin II.
-
Establishing the epigenetic status of the Prader-Willi/Angelman imprinting center in the gametes and embryo.
-
Establishment and characterization of conditionally immortalized cells from the mouse urogenital ridge.
-
Establishment of a high-efficiency SNP-based framework marker set for Arabidopsis.
-
Estrogen excess associated with novel gain-of-function mutations affecting the aromatase gene.
-
Estrogen receptor alpha (ESR1) mutant A908G is not a common feature in benign and malignant proliferations of the breast.
-
Estrogen receptor gene disruption: molecular characterization and experimental and clinical phenotypes.
-
Ethanol increases apolipoprotein B mRNA editing in rat primary hepatocytes and McArdle cells.
-
Ets-1 and runx2 regulate transcription of a metastatic gene, osteopontin, in murine colorectal cancer cells.
-
Eukaryotic transcription termination factor La mediates transcript release and facilitates reinitiation by RNA polymerase III.
-
Evaluating the specificity of antisense oligonucleotide conjugates. A DNA array analysis.
-
Evaluation of 23S rRNA PCR primers for use in phylogenetic studies of bacterial diversity.
-
Evaluation of Lipin 2 as a candidate gene for autosomal dominant 1 high-grade myopia.
-
Evaluation of microsatellite instability, hMLH1 expression and hMLH1 promoter hypermethylation in defining the MSI phenotype of colorectal cancer.
-
Evaluation of the genomic extent of effects of fixed inversion differences on intraspecific variation and interspecific gene flow in Drosophila pseudoobscura and D. persimilis.
-
Evidence for a disease-resistance pathway in rice similar to the NPR1-mediated signaling pathway in Arabidopsis.
-
Evidence for a dual role for TC4 protein in regulating nuclear structure and cell cycle progression.
-
Evidence for a near-resonant charge transfer mechanism for double-stranded peptide nucleic acid.
-
Evidence for independent recruitment of zeta-crystallin/quinone reductase (CRYZ) as a crystallin in camelids and hystricomorph rodents.
-
Evidence for involvement of GNB1L in autism.
-
Evidence for positive and negative regulatory elements in the 5'-flanking sequence of the mouse sparc (osteonectin) gene.
-
Evidence for rapid disappearance of initially expanded HIV-specific CD8+ T cell clones during primary HIV infection.
-
Evidence for sexuality in the opportunistic fungal pathogen Aspergillus fumigatus.
-
Evidence for substantial effect modification by gender in a large-scale genetic association study of the metabolic syndrome among coronary heart disease patients.
-
Evidence for the intertwined dimer of the cytochrome bc(1) complex in solution.
-
Evidence from molecular cloning that SPARC, a major product of mouse embryo parietal endoderm, is related to an endothelial cell 'culture shock' glycoprotein of Mr 43,000.
-
Evidence from normal expression and targeted misexpression that bone morphogenetic protein (Bmp-4) plays a role in mouse embryonic lung morphogenesis.
-
Evidence from opsin genes rejects nocturnality in ancestral primates.
-
Evidence of ultraviolet type mutations in xeroderma pigmentosum melanomas.
-
Evidence that Mothers-against-dpp-related 1 (Madr1) plays a role in the initiation and maintenance of spermatogenesis in the mouse.
-
Evolution and diversity in human herpes simplex virus genomes.
-
Evolution and probable transmission of intersubtype recombinant human immunodeficiency virus type 1 in a Zambian couple.
-
Evolution of a complex eukaryotic gene.
-
Evolution of a tumorigenic property conferred by glycophosphatidyl-inositol membrane anchors of carcinoembryonic antigen gene family members during the primate radiation.
-
Evolution of king crabs from hermit crab ancestors.
-
Evolution of regeneration and fission in annelids: insights from engrailed- and orthodenticle-class gene expression.
-
Evolution of the 12 kDa FK506-binding protein gene.
-
Evolution of the gene encoding mitochondrial intermediate peptidase and its cosegregation with the A mating-type locus of mushroom fungi.
-
Evolution of the trnF(GAA) gene in Arabidopsis relatives and the brassicaceae family: monophyletic origin and subsequent diversification of a plastidic pseudogene.
-
Evolutionary adaptation of the amino acid and codon usage of the mosquito sodium channel following insecticide selection in the field mosquitoes.
-
Evolutionary analysis of the well characterized endo16 promoter reveals substantial variation within functional sites.
-
Evolutionary and phylogenetic insights from a nuclear genome sequence of the extinct, giant, "subfossil" koala lemur Megaladapis edwardsi.
-
Evolutionary bottlenecks in the agents of tuberculosis, leprosy, and paratuberculosis.
-
Evolutionary conservation of primate lymphocryptovirus microRNA targets.
-
Evolutionary implications of primate endogenous retroviruses.
-
Evolutionary mechanisms for eucaryotic genes.
-
Evolutionary relationships of endemic/epidemic and sylvatic dengue viruses.
-
Evolutionary relationships within the fungi: analyses of nuclear small subunit rRNA sequences.
-
Excision and transposition of Tn5 as an SOS activity in Escherichia coli.
-
Excision repair reduces doxorubicin-induced genotoxicity.
-
Exercise stimulates Pgc-1alpha transcription in skeletal muscle through activation of the p38 MAPK pathway.
-
Exome sequencing detection of two untranslated GFPT1 mutations in a family with limb-girdle myasthenia.
-
Exome sequencing followed by large-scale genotyping fails to identify single rare variants of large effect in idiopathic generalized epilepsy.
-
Exome sequencing followed by large-scale genotyping suggests a limited role for moderately rare risk factors of strong effect in schizophrenia.
-
Exon 10b of the NF1 gene represents a mutational hotspot and harbors a recurrent missense mutation Y489C associated with aberrant splicing.
-
Exon circularization in mammalian nuclear extracts.
-
Exon junction complexes mediate the enhancing effect of splicing on mRNA expression.
-
Exon skipping in purine nucleoside phosphorylase mRNA processing leading to severe immunodeficiency.
-
Exosome-Mediated Delivery of Inducible miR-423-5p Enhances Resistance of MRC-5 Cells to Rabies Virus Infection.
-
Expansion of adult beta-cell mass in response to increased metabolic demand is dependent on HNF-4alpha.
-
Expansion of somatically reverted memory CD8+ T cells in patients with X-linked lymphoproliferative disease caused by selective pressure from Epstein-Barr virus.
-
Expansion of the alpha 2-adrenergic receptor family: cloning and characterization of a human alpha 2-adrenergic receptor subtype, the gene for which is located on chromosome 2.
-
Expansion of the human mu-opioid receptor gene architecture: novel functional variants.
-
Experimental evidence for the secondary structure of the hepatitis delta virus ribozyme.
-
Expression analysis of endoglin missense and truncation mutations: insights into protein structure and disease mechanisms.
-
Expression analysis of four endoglin missense mutations suggests that haploinsufficiency is the predominant mechanism for hereditary hemorrhagic telangiectasia type 1.
-
Expression and characterization of recombinant human factor V and a mutant lacking a major portion of the connecting region.
-
Expression and function of microRNAs encoded by Kaposi's sarcoma-associated herpesvirus.
-
Expression and function of the gamma c subunit of the IL-2, IL-4, and IL-7 receptors. Distinct interaction of gamma c in the IL-4 receptor.
-
Expression and function of the uvsW gene of bacteriophage T4.
-
Expression and functional characterization of chimeras between human and bovine vitamin-K-dependent protein-S-defining modules important for the species specificity of the activated protein C cofactor activity.
-
Expression and sequence analysis of a cDNA encoding the orotidine-5'-monophosphate decarboxylase domain from Ehrlich ascites uridylate synthase.
-
Expression cloning and characterization of the TGF-beta type III receptor.
-
Expression cloning of the TGF-beta type II receptor, a functional transmembrane serine/threonine kinase.
-
Expression cloning of type 2 angiotensin II receptor reveals a unique class of seven-transmembrane receptors.
-
Expression of CD44 variants in human inflammatory synovitis.
-
Expression of E-selectin messenger RNA and protein in rheumatoid arthritis.
-
Expression of Sry, the mouse sex determining gene.
-
Expression of a candidate sex-determining gene during mouse testis differentiation.
-
Expression of a cloned human interleukin-2 cDNA is enhanced by the substitution of a heterologous mRNA leader region.
-
Expression of a distinctive BCR-ABL oncogene in Ph1-positive acute lymphocytic leukemia (ALL).
-
Expression of a functional alpha-macroglobulin receptor binding domain in Escherichia coli.
-
Expression of a functional antizearalenone single-chain Fv antibody in transgenic Arabidopsis plants.
-
Expression of a murine cytomegalovirus early-late protein in "latently" infected mice.
-
Expression of alternatively spliced human T-lymphotropic virus type I pX mRNA in infected cell lines and in primary uncultured cells from patients with adult T-cell leukemia/lymphoma and healthy carriers.
-
Expression of an EF-1 alpha-like rat cDNA, S1, in E. coli and production of a rabbit polyclonal antiserum to the recombinant protein.
-
Expression of an abundant alternatively spliced form of the cystic fibrosis transmembrane conductance regulator (CFTR) gene is not associated with a cAMP-activated chloride conductance.
-
Expression of candidate pro-GnRH processing enzymes in rat hypothalamus and an immortalized hypothalamic neuronal cell line.
-
Expression of cyp26b1 during zebrafish early development.
-
Expression of cytokine mRNA in murine splenic dendritic cells and better induction of T cell-derived cytokines by dendritic cells than by macrophages during in vitro costimulation assay using specific antigens.
-
Expression of erythropoietin receptor splice variants in human cancer.
-
Expression of functional chicken oviduct progesterone receptors in yeast (Saccharomyces cerevisiae).
-
Expression of normal and novel glucokinase mRNAs in anterior pituitary and islet cells.
-
Expression of p53 in human neuroblastoma- and neuroepithelioma-derived cell lines.
-
Expression of recombinant human methylmalonyl-CoA mutase: in primary mut fibroblasts and Saccharomyces cerevisiae.
-
Expression of the Pseudomonas syringae avirulence protein AvrB in plant cells alleviates its dependence on the hypersensitive response and pathogenicity (Hrp) secretion system in eliciting genotype-specific hypersensitive cell death.
-
Expression of the candidate tumor suppressor gene hSRBC is frequently lost in primary lung cancers with and without DNA methylation.
-
Expression of the human poliovirus receptor/CD155 gene is activated by sonic hedgehog.
-
Expression of the noncatalytic domain of the NIMA kinase causes a G2 arrest in Aspergillus nidulans.
-
Expression of transforming growth factor beta type II receptor leads to reduced malignancy in human breast cancer MCF-7 cells.
-
Expression of transforming growth factor-beta type II receptor in rat lung is regulated during development.
-
Extended ORF8 Gene Region Is Valuable in the Epidemiological Investigation of Severe Acute Respiratory Syndrome-Similar Coronavirus.
-
Extending assembly of short DNA sequences to handle error.
-
Extensive DNA sequence conservation throughout the Mycobacterium tuberculosis complex.
-
Extensive chloroplast haplotype variation indicates Pleistocene hybridization and radiation of North American Arabis drummondii, A. x divaricarpa, and A. holboellii (Brassicaceae).
-
Extensive junctional diversity of rearranged human T cell receptor delta genes.
-
Extracellular signal-regulated kinase plays an essential role in hypertrophic agonists, endothelin-1 and phenylephrine-induced cardiomyocyte hypertrophy.
-
Extracellular signal-regulated kinase regulation of tumor necrosis factor-alpha mRNA nucleocytoplasmic transport requires TAP-NxT1 binding and the AU-rich element.
-
Extrinsic coagulation blockade attenuates lung injury and proinflammatory cytokine release after intratracheal lipopolysaccharide.
-
FK 506-binding protein proline rotamase is a target for the immunosuppressive agent FK 506 in Saccharomyces cerevisiae.
-
FKBP12 controls aspartate pathway flux in Saccharomyces cerevisiae to prevent toxic intermediate accumulation.
-
FMRP targets distinct mRNA sequence elements to regulate protein expression.
-
Facilitated diffusion during catalysis by EcoRI endonuclease. Nonspecific interactions in EcoRI catalysis.
-
Facilitation of robust growth of Prochlorococcus colonies and dilute liquid cultures by "helper" heterotrophic bacteria.
-
Factors affecting harp seal (Pagophilus groenlandicus) strandings in the Northwest Atlantic.
-
Facultative role of germinal centers and T cells in the somatic diversification of IgVH genes.
-
Failure of the ILD to determine data combinability for slow loris phylogeny.
-
Familial association of primary pulmonary hypertension and a new low-oxygen affinity beta-chain hemoglobinopathy, Hb Washtenaw.
-
Familial erythrocytosis associated with a short deletion in the erythropoietin receptor gene.
-
Familial recurrence of SOX2 anophthalmia syndrome: phenotypically normal mother with two affected daughters.
-
Fas on renal parenchymal cells does not promote autoimmune nephritis in MRL mice.
-
Fatal granulomatous Acanthamoeba encephalitis mimicking a stroke, diagnosed by correlation of results of sequential magnetic resonance imaging, biopsy, in vitro culture, immunofluorescence analysis, and molecular analysis.
-
Female steroid hormones use signal transducers and activators of transcription protein-mediated pathways to modulate the expression of T-bet in epithelial cells: a mechanism for local immune regulation in the human reproductive tract.
-
Fibroblast growth factor 20 polymorphisms and haplotypes strongly influence risk of Parkinson disease.
-
Finding regulatory DNA motifs using alignment-free evolutionary conservation information.
-
Fine localization of the CMT4A locus using a PAC contig and haplotype analysis.
-
Fine-scale mapping of recombination rate in Drosophila refines its correlation to diversity and divergence.
-
Fine-scale variation in meiotic recombination in Mimulus inferred from population shotgun sequencing.
-
Fine-structure mapping of meiosis-specific double-strand DNA breaks at a recombination hotspot associated with an insertion of telomeric sequences upstream of the HIS4 locus in yeast.
-
Finishing the euchromatic sequence of the human genome.
-
Flanking nuclear matrix attachment regions synergize with the T cell receptor delta enhancer to promote V(D)J recombination.
-
Fluorescent peptide displacement as a general assay for screening small molecule libraries against RNA.
-
Foamy virus Bet proteins function as novel inhibitors of the APOBEC3 family of innate antiretroviral defense factors.
-
Foci of endemic simian immunodeficiency virus infection in wild-living eastern chimpanzees (Pan troglodytes schweinfurthii).
-
Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing.
-
Formaldehyde-induced mutagenesis in Saccharomyces cerevisiae: molecular properties and the roles of repair and bypass systems.
-
Four new adenosine deaminase mutations, altering a zinc-binding histidine, two conserved alanines, and a 5' splice site.
-
FoxA2, Nkx2.2, and PDX-1 regulate islet beta-cell-specific mafA expression through conserved sequences located between base pairs -8118 and -7750 upstream from the transcription start site.
-
Fragments of ATM which have dominant-negative or complementing activity.
-
Frameshift intermediates in homopolymer runs are removed efficiently by yeast mismatch repair proteins.
-
Frameshift mutagenesis: the roles of primer-template misalignment and the nonhomologous end-joining pathway in Saccharomyces cerevisiae.
-
Frameshifts and deletions during in vitro translesion synthesis past Pt-DNA adducts by DNA polymerases beta and eta.
-
Frequent detection of bcl-2/JH translocations in human blood and organ samples by a quantitative polymerase chain reaction assay.
-
Frequent fusion of the JAZF1 and JJAZ1 genes in endometrial stromal tumors.
-
From genome-wide to candidate gene: an investigation of variation at the major histocompatibility complex in common bottlenose dolphins exposed to harmful algal blooms.
-
From offshore to onshore: multiple origins of shallow-water corals from deep-sea ancestors.
-
FtsZ, a prokaryotic homolog of tubulin?
-
Full-length nucleotide sequence of ERMAP alleles encoding Scianna (SC) antigens.
-
Function of the hydrophilic carboxyl terminus of type II DNA topoisomerase from Drosophila melanogaster. I. In vitro studies.
-
Functional Analysis and Fine Mapping of the 9p22.2 Ovarian Cancer Susceptibility Locus.
-
Functional analysis of a complementary DNA for the 50-kilodalton subunit of calmodulin kinase II.
-
Functional analysis of interactions between Tat and the trans-activation response element of human immunodeficiency virus type 1 in cells.
-
Functional analysis of intra-allelic variation at NACP-Rep1 in the alpha-synuclein gene.
-
Functional analysis of the Tat trans activator of human immunodeficiency virus type 2.
-
Functional analysis of the transforming growth factor beta responsive elements in the WAF1/Cip1/p21 promoter.
-
Functional association of the parkin gene promoter with idiopathic Parkinson's disease.
-
Functional characterization of a complex protein-DNA-binding domain located within the human immunodeficiency virus type 1 long terminal repeat leader region.
-
Functional characterization of a unique liver gene promoter.
-
Functional comparison of the Rev trans-activators encoded by different primate immunodeficiency virus species.
-
Functional complexity and regulation through RNA dynamics.
-
Functional high efficiency expression of cloned leukocyte chemoattractant receptor cDNAs.
-
Functional polymorphism in ABCA1 influences age of symptom onset in coronary artery disease patients.
-
Functional repair of a mutant chloride channel using a trans-splicing ribozyme.
-
Functional trait evolution in Sphagnum peat mosses and its relationship to niche construction.
-
Functionally important regions of the factor IX gene have a low rate of polymorphism and a high rate of mutation in the dinucleotide CpG.
-
Functions of fission yeast orp2 in DNA replication and checkpoint control.
-
Functions of the myosin ATP and actin binding sites are required for C. elegans thick filament assembly.
-
Further clinical and molecular delineation of the 15q24 microdeletion syndrome.
-
Further investigation of simian immunodeficiency virus Vif function in human cells.
-
Fusion of the termini of the murine cytomegalovirus genome after infection.
-
Fusions of elastin-like polypeptides to pharmaceutical proteins.
-
G protein signaling and vein graft intimal hyperplasia: reduction of intimal hyperplasia in vein grafts by a Gbetagamma inhibitor suggests a major role of G protein signaling in lesion development.
-
GABA-induced chemokinesis and NGF-induced chemotaxis of embryonic spinal cord neurons.
-
GABP and PU.1 compete for binding, yet cooperate to increase CD18 (beta 2 leukocyte integrin) transcription.
-
GC content elevates mutation and recombination rates in the yeast Saccharomyces cerevisiae.
-
GC sequence specific recognition by an N-formamido, C-terminus-modified and imidazole-containing analogue of netropsin.
-
GRP94/gp96 elicits ERK activation in murine macrophages. A role for endotoxin contamination in NF-kappa B activation and nitric oxide production.
-
GTPase activating specificity of RGS12 and binding specificity of an alternatively spliced PDZ (PSD-95/Dlg/ZO-1) domain.
-
Gains and overexpression identify DEK and E2F3 as targets of chromosome 6p gains in retinoblastoma.
-
Galanin antisense oligonucleotides reduce galanin levels in dorsal root ganglia and induce autotomy in rats after axotomy.
-
Gateway-compatible tissue-specific vectors for plant transformation.
-
Gene disruption with PCR products in Saccharomyces cerevisiae.
-
Gene expression of the renin-angiotensin system in human tissues. Quantitative analysis by the polymerase chain reaction.
-
Gene silencing using RNA interference in embryonic stem cells.
-
Gene targeting to the ROSA26 locus directed by engineered zinc finger nucleases
-
Gene up-regulation in heart during mammalian hibernation.
-
Generation and characterization of a mouse/human chimeric antibody directed against extracellular matrix protein tenascin.
-
Generation of a polyclonal Fab phage display library to the protozoan parasite Cryptosporidium parvum.
-
Generation of a polyclonal fab phage display library to the human breast carcinoma cell line BT-20.
-
Generation of infectious molecular clones of simian immunodeficiency virus from fecal consensus sequences of wild chimpanzees.
-
Generation of nuclease resistant circular RNA decoys for HIV-Tat and HIV-Rev by autocatalytic splicing.
-
Generation of nuclease resistant circular RNA decoys for HIV-Tat and HIV-Rev by autocatalytic splicing.
-
Generation of species cross-reactive aptamers using "toggle" SELEX.
-
Genetic Architecture of a Morphological Shape Difference Between Two Drosophila Species
-
Genetic analysis of a family with hereditary glomuvenous malformations.
-
Genetic analysis of a meiotic recombination hotspot on chromosome III of Saccharomyces cerevisiae.
-
Genetic analysis of a morphological shape difference in the male genitalia of Drosophila simulans and D. mauritiana.
-
Genetic analysis of sinonasal adenocarcinoma phenotypes: distinct alterations of histogenetic significance.
-
Genetic analysis of the cofactor requirement for human immunodeficiency virus type 1 Tat function.
-
Genetic and phenotypic changes accompanying the emergence of epizootic subtype IC Venezuelan equine encephalitis viruses from an enzootic subtype ID progenitor.
-
Genetic basis for p53 overexpression in human breast cancer.
-
Genetic basis of glycogen storage disease type 1a: prevalent mutations at the glucose-6-phosphatase locus.
-
Genetic changes associated with floral adaptation restrict future evolutionary potential.
-
Genetic comparisons yield insight into the evolution of enamel thickness during human evolution.
-
Genetic control of blood pressure and the angiotensinogen locus.
-
Genetic control of chromosome length in yeast.
-
Genetic deletion of the Tas2r143/Tas2r135/Tas2r126 cluster reveals that TAS2Rs may not mediate bitter tastant-induced bronchodilation.
-
Genetic diagnosis in Lafora disease: genotype-phenotype correlations and diagnostic pitfalls.
-
Genetic diversity among Mycobacterium avium complex strains recovered from children with and without human immunodeficiency virus infection.
-
Genetic diversity in the Mycobacterium tuberculosis complex based on variable numbers of tandem DNA repeats.
-
Genetic diversity of human immunodeficiency virus type 2: evidence for distinct sequence subtypes with differences in virus biology.
-
Genetic diversity of the Cryptococcus species complex suggests that Cryptococcus gattii deserves to have varieties.
-
Genetic engineering of a single-chain antibody fragment for surface immobilization in an optical biosensor.
-
Genetic engineering of vein grafts resistant to atherosclerosis.
-
Genetic evidence for a novel familial Alzheimer's disease locus on chromosome 14.
-
Genetic evidence for preferential strand transfer during meiotic recombination in yeast.
-
Genetic evidence that the meiotic recombination hotspot at the HIS4 locus of Saccharomyces cerevisiae does not represent a site for a symmetrically processed double-strand break.
-
Genetic heterogeneity in MCAD deficiency: frequency of K329E allele and identification of three additional mutant alleles.
-
Genetic heterogeneity of diffuse large B-cell lymphoma.
-
Genetic mapping of a gene causing hypertension in the stroke-prone spontaneously hypertensive rat.
-
Genetic mosaics reveal both cell-autonomous and cell-nonautonomous function of murine p27Kip1.
-
Genetic regulation of telomere-telomere fusions in the yeast Saccharomyces cerevisae.
-
Genetic relationships and evolution of genotypes of yellow fever virus and other members of the yellow fever virus group within the Flavivirus genus based on the 3' noncoding region.
-
Genetic risk and carcinogen exposure: a common inherited defect of the carcinogen-metabolism gene glutathione S-transferase M1 (GSTM1) that increases susceptibility to bladder cancer.
-
Genetic structure and DNA sequences at junctions involved in the rearrangements of Bacillus subtilis strains carrying the trpE26 mutation.
-
Genetic studies in Alzheimer's disease with an NACP/alpha-synuclein polymorphism.
-
Genetic typing of HIV-2 from a Senegalese/German heterosexual transmission.
-
Genetic variability of Bacillus anthracis and related species.
-
Genetic variant rs16430 6bp > 0bp at the microRNA-binding site in TYMS and risk of sporadic breast cancer risk in non-Hispanic white women aged ≤ 55 years.
-
Genetic variants at the miR-124 binding site on the cytoskeleton-organizing IQGAP1 gene confer differential predisposition to breast cancer.
-
Genetic variants in MGMT and risk of lung cancer in Southeastern Chinese: a haplotype-based analysis.
-
Genetic variation in aldosterone synthase predicts plasma glucose levels.
-
Genetic variation in the 3' non-coding region of dengue viruses.
-
Genetic variation in the spread of Drosophila subobscura from a nonequilibrium population.
-
Genetic variation in yellow fever virus: duplication in the 3' noncoding region of strains from Africa.
-
Genetic variation of HIV type 1 in four World Health Organization-sponsored vaccine evaluation sites: generation of functional envelope (glycoprotein 160) clones representative of sequence subtypes A, B, C, and E. WHO Network for HIV Isolation and Characterization.
-
Genetic variation within and among populations of the threatened lichen Lobaria pulmonaria in Switzerland and implications for its conservation.
-
Genetically encoded synthesis of protein-based polymers with precisely specified molecular weight and sequence by recursive directional ligation: examples from the elastin-like polypeptide system.
-
Genetically engineered calmodulins differentially activate target enzymes.
-
Genetically stable picornavirus expression vectors with recombinant internal ribosomal entry sites.
-
Genome maps 7. The human transcript map. Wall chart.
-
Genome sequence of Blochmannia pennsylvanicus indicates parallel evolutionary trends among bacterial mutualists of insects.
-
Genome sequencing and comparative analysis of Saccharomyces cerevisiae strain YJM789.
-
Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition.
-
Genome sequencing unveils a regulatory landscape of platelet reactivity.
-
Genome wide analyses reveal little evidence for adaptive evolution in many plant species.
-
Genome-wide analysis of the regulation of Cu metabolism in Cryptococcus neoformans.
-
Genome-wide association studies identify susceptibility loci for epithelial ovarian cancer in east Asian women.
-
Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm.
-
Genome-wide identification of calcium-response factor (CaRF) binding sites predicts a role in regulation of neuronal signaling pathways.
-
Genome-wide mutagenesis of influenza virus reveals unique plasticity of the hemagglutinin and NS1 proteins.
-
Genome-wide significant risk associations for mucinous ovarian carcinoma.
-
Genomes of Ashbya fungi isolated from insects reveal four mating-type loci, numerous translocations, lack of transposons, and distinct gene duplications.
-
Genomewide view of gene silencing by small interfering RNAs.
-
Genomic amplification with transcript sequencing.
-
Genomic cloning of hGSTP1*C, an allelic human Pi class glutathione S-transferase gene variant and functional characterization of its retinoic acid response elements.
-
Genomic landscapes of breast fibroepithelial tumors.
-
Genomic organization and cloning of the human homologue of murine Sipa-1.
-
Genomic organization and polymorphism of human angiotensin II type 2 receptor: no evidence for its gene mutation in two families of human premature ovarian failure syndrome.
-
Genomic organization of rat rDNA.
-
Genomic organization of the human T-cell antigen-receptor alpha/delta locus.
-
Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene.
-
Genomic sequence and expression of a cloned human carbonyl reductase gene with daunorubicin reductase activity.
-
Genomic signatures of diet-related shifts during human origins.
-
Genomic structure and amino acid sequence domains of the human La autoantigen.
-
Genomic structure and chromosomal localization of the novel ETS factor, PE-2 (ERF).
-
Genomic structure and embryonic expression of estrogen receptor beta a (ERbetaa) in zebrafish (Danio rerio).
-
Genomic structure of the EPHA1 receptor tyrosine kinase gene.
-
Genomic sweeping for hypermethylated genes.
-
Genomics and expression profiles of the Hedgehog and Notch signaling pathways in sea urchin development.
-
Genotype-phenotype correlation in two frequent mutations and mutation update in type III glycogen storage disease.
-
Germline and somatic SMARCA4 mutations characterize small cell carcinoma of the ovary, hypercalcemic type.
-
Germline sequences of V(H)7183 gene family members in C57BL/6 mice demonstrate natural selection of particular sequences during recent evolution.
-
Gill-specific transcriptional regulation of Na+/K+ -ATPase alpha-subunit in the euryhaline shore crab Pachygrapsus marmoratus: sequence variants and promoter structure.
-
Glioblastoma multiforme and the epidermal growth factor receptor.
-
Global Survey of Variation in a Human Olfactory Receptor Gene Reveals Signatures of Non-Neutral Evolution.
-
Global analysis of the evolution and mechanism of echinocandin resistance in Candida glabrata.
-
Global mapping of meiotic recombination hotspots and coldspots in the yeast Saccharomyces cerevisiae.
-
Global patterns in peatmoss biodiversity.
-
Global transcriptional and proteomic analysis of the Sig1 heat shock regulon of Deinococcus radiodurans.
-
Glu-111 is required for activation of the DNA cleavage center of EcoRI endonuclease.
-
Glucokinase and glucose transporter expression in liver and islets: implications for control of glucose homoeostasis.
-
Glucose-dependent insulinotropic peptide (GIP) gene expression in the rat salivary gland.
-
Glutamine-mediated dual regulation of heat shock transcription factor-1 activation and expression.
-
Glyceraldehyde-3-phosphate dehydrogenase is regulated on a daily basis by the circadian clock.
-
Glycogen storage disease type IV: novel mutations and molecular characterization of a heterogeneous disorder.
-
Glycogen synthase: a putative locus for diet-induced hyperglycemia.
-
Glycosaminoglycan binding properties of natural venezuelan equine encephalitis virus isolates.
-
Gq-dependent signaling upregulates COX2 in glomerular podocytes.
-
Granulomatous skin lesions in moray eels caused by a novel Mycobacterium species related to Mycobacterium triplex.
-
Group I intron self-splicing with adenosine: evidence for a single nucleoside-binding site.
-
Group I permuted intron-exon (PIE) sequences self-splice to produce circular exons.
-
Group II introns designed to insert into therapeutically relevant DNA target sites in human cells.
-
Group-I intron family in the nuclear ribosomal RNA small subunit genes of Cenococcum geophilum isolates.
-
Guanine repeat-containing sequences confer transcription-dependent instability in an orientation-specific manner in yeast.
-
H19, a developmentally regulated gene, is reexpressed in rat vascular smooth muscle cells after injury.
-
HDV ribozyme activity in monovalent cations.
-
HIV DNA-Adenovirus Multiclade Envelope Vaccine Induces gp41 Antibody Immunodominance in Rhesus Macaques.
-
HIV evolution in early infection: selection pressures, patterns of insertion and deletion, and the impact of APOBEC.
-
HIV-1 Rev promotes the nuclear export of unspliced and singly spliced RNAs in a mammalian cell-free export system.
-
HIV-1 sequence subtype D in the United States.
-
HIV-1 structural gene expression requires binding of the Rev trans-activator to its RNA target sequence.
-
HLA-A0201 positive pancreatic cell lines: new findings and discrepancies.
-
HNF-3 beta as a regulator of floor plate development.
-
Half-site arrangement of hybrid glucocorticoid and thyroid hormone response elements specifies thyroid hormone receptor complex binding to DNA and transcriptional activity.
-
Haplotypes of two variants in p16 (CDKN2/MTS-1/INK4a) exon 3 and risk of squamous cell carcinoma of the head and neck: a case-control study.
-
Hb Catonsville (glutamic acid inserted between Pro-37(C2)alpha and Thr-38(C3)alpha). Nonallelic gene conversion in the globin system?
-
Hel-N1, an RNA-binding protein, is a ligand for an A + U rich region of the GLUT1 3' UTR.
-
Hel-N1/Hel-N2 proteins are bound to poly(A)+ mRNA in granular RNP structures and are implicated in neuronal differentiation.
-
Hel-N1: an autoimmune RNA-binding protein with specificity for 3' uridylate-rich untranslated regions of growth factor mRNAs.
-
Helper T cell subsets for immunoglobulin A responses: oral immunization with tetanus toxoid and cholera toxin as adjuvant selectively induces Th2 cells in mucosa associated tissues.
-
Helper Th1 and Th2 cell responses following mucosal or systemic immunization with cholera toxin.
-
Helping Relationships and Genetic Propensities: A Combinatoric Study of DRD2, Mentoring, and Educational Continuation
-
Hematopoietic-specific Stat5-null mice display microcytic hypochromic anemia associated with reduced transferrin receptor gene expression.
-
Hemorrhage in lesions caused by cowpox virus is induced by a viral protein that is related to plasma protein inhibitors of serine proteases.
-
Hepatic and neuromuscular forms of glycogen storage disease type IV caused by mutations in the same glycogen-branching enzyme gene.
-
Hepatitis delta virus ribozymes fold to generate a solvent-inaccessible core with essential nucleotides near the cleavage site phosphate.
-
Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice.
-
Hepcidin, a candidate modifier of the hemochromatosis phenotype in mice.
-
Heterodimerization and deoxyribonucleic acid-binding properties of a retinoid X receptor-related factor.
-
High incidence of T-cell tumors in E2A-null mice and E2A/Id1 double-knockout mice.
-
High prevalence of rare dopamine receptor D4 alleles in children diagnosed with attention-deficit hyperactivity disorder.
-
High-depth sequencing of over 750 genes supports linear progression of primary tumors and metastases in most patients with liver-limited metastatic colorectal cancer.
-
High-level expression of Escherichia coli NADPH-sulfite reductase: requirement for a cloned cysG plasmid to overcome limiting siroheme cofactor.
-
High-level misincorporation of lysine for arginine at AGA codons in a fusion protein expressed in Escherichia coli.
-
High-level production of recombinant human lysosomal acid alpha-glucosidase in Chinese hamster ovary cells which targets to heart muscle and corrects glycogen accumulation in fibroblasts from patients with Pompe disease.
-
High-resolution genome-wide in vivo footprinting of diverse transcription factors in human cells.
-
Highly coordinated gene regulation in mouse skeletal muscle regeneration.
-
Highly divergent lentiviral Tat proteins activate viral gene expression by a common mechanism.
-
Highly effective control of an AIDS virus challenge in macaques by using vesicular stomatitis virus and modified vaccinia virus Ankara vaccine vectors in a single-boost protocol.
-
Histone gene clusters of the newt notophthalmus are separated by long tracts of satellite DNA.
-
Histone methyltransferase SETDB1 is required for prostate cancer cell proliferation, migration and invasion.
-
Histone modifications within the human X centromere region.
-
Historical effects on beta diversity and community assembly in Amazonian trees.
-
Homologs of the vancomycin resistance D-Ala-D-Ala dipeptidase VanX in Streptomyces toyocaensis, Escherichia coli and Synechocystis: attributes of catalytic efficiency, stereoselectivity and regulation with implications for function.
-
Homozygous APC-resistance combined with inherited type I protein S deficiency in a young boy with severe thrombotic disease.
-
Horizontal transfer of an adaptive chimeric photoreceptor from bryophytes to ferns
-
Host-symbiont stability and fast evolutionary rates in an ant-bacterium association: cospeciation of camponotus species and their endosymbionts, candidatus blochmannia.
-
Hotspot sites for acridine-induced frameshift mutations in bacteriophage T4 correspond to sites of action of the T4 type II topoisomerase.
-
How the EcoRI endonuclease recognizes and cleaves DNA.
-
Human DNA-activated protein kinase (DNA-PK) is homologous to phosphatidylinositol kinases.
-
Human G(alpha q): cDNA and tissue distribution.
-
Human GFRA1: cloning, mapping, genomic structure, and evaluation as a candidate gene for Hirschsprung disease susceptibility.
-
Human Gi protein alpha-subunit: deduction of amino acid structure from a cloned cDNA.
-
Human La antigen is required for the hepatitis C virus internal ribosome entry site-mediated translation.
-
Human MafG is a functional partner for p45 NF-E2 in activating globin gene expression.
-
Human MutSalpha recognizes damaged DNA base pairs containing O6-methylguanine, O4-methylthymine, or the cisplatin-d(GpG) adduct.
-
Human adipocyte lipid-binding protein: purification of the protein and cloning of its complementary DNA.
-
Human and mouse alpha-synuclein genes: comparative genomic sequence analysis and identification of a novel gene regulatory element.
-
Human and rat mast cell high-affinity immunoglobulin E receptors: characterization of putative alpha-chain gene products.
-
Human and rat peroxisome proliferator activated receptors (PPARs) demonstrate similar tissue distribution but different responsiveness to PPAR activators.
-
Human brain glycogen phosphorylase. Cloning, sequence analysis, chromosomal mapping, tissue expression, and comparison with the human liver and muscle isozymes.
-
Human calcium-calmodulin dependent protein kinase I: cDNA cloning, domain structure and activation by phosphorylation at threonine-177 by calcium-calmodulin dependent protein kinase I kinase.
-
Human catechol-O-methyltransferase haplotypes modulate protein expression by altering mRNA secondary structure.
-
Human colonic biota studied by ribosomal DNA sequence analysis.
-
Human colorectal carcinomas specifically accumulate Mr 42,000 ubiquitin-conjugated cytokeratin 8 fragments.
-
Human factor IXLincoln Park: a molecular characterization.
-
Human glycogen debranching enzyme gene (AGL): complete structural organization and characterization of the 5' flanking region.
-
Human granulosa-luteal and cumulus cells express transforming growth factors-beta type 1 and type 2 mRNA.
-
Human infection by genetically diverse SIVSM-related HIV-2 in west Africa.
-
Human lung cancer cell lines exhibit resistance to retinoic acid treatment.
-
Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs.
-
Human mononuclear phagocyte inducible nitric oxide synthase (iNOS): analysis of iNOS mRNA, iNOS protein, biopterin, and nitric oxide production by blood monocytes and peritoneal macrophages.
-
Human nonsyndromic hereditary deafness DFNA17 is due to a mutation in nonmuscle myosin MYH9.
-
Human promyelocytic leukemia HL-60 cell proliferation and c-myc protein expression are inhibited by an antisense pentadecadeoxynucleotide targeted against c-myc mRNA.
-
Human smooth muscle alpha-actin gene is a transcriptional target of the p53 tumor suppressor protein.
-
Human sterile alpha motif domain 9, a novel gene identified as down-regulated in aggressive fibromatosis, is absent in the mouse.
-
Human strand-specific mismatch repair occurs by a bidirectional mechanism similar to that of the bacterial reaction.
-
Human type 2 angiotensin II receptor gene: cloned, mapped to the X chromosome, and its mRNA is expressed in the human lung.
-
Humoral immune responses in Cr2-/- mice: enhanced affinity maturation but impaired antibody persistence.
-
Hybrid male sterility in Mimulus (Phrymaceae) is associated with a geographically restricted mitochondrial rearrangement.
-
Hybridization probes for conventional DNA fingerprinting used as single primers in the polymerase chain reaction to distinguish strains of Cryptococcus neoformans.
-
Hydralazine differentially increases mRNAs for the alpha and beta subunits of prolyl 4-hydroxylase whereas it decreases pro alpha 1(I) collagen mRNAs in human skin fibroblasts.
-
Hypermutability and mismatch repair deficiency in RER+ tumor cells.
-
Hypertension and impaired glycine handling in mice lacking the orphan transporter XT2.
-
IFN-gamma production in response to neuropathogenic Cas-Br-M murine leukemia virus infection.
-
Identification and cloning of a negative regulator of systemic acquired resistance, SNI1, through a screen for suppressors of npr1-1
-
Identification and analysis of eukaryotic promoters: recent computational approaches.
-
Identification and cell type specificity of the tyrosine hydroxylase gene promoter.
-
Identification and characterization of a cDNA encoding cytochrome P450 3A from the fresh water teleost medaka (Oryzias latipes).
-
Identification and characterization of a human homolog of the Schizosaccharomyces pombe ras-like gene YPT-3.
-
Identification and characterization of a new cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody.
-
Identification and characterization of a novel family of cyclic nucleotide phosphodiesterases.
-
Identification and characterization of an agonistic aptamer against the T cell costimulatory receptor, OX40.
-
Identification and characterization of cell type-specific and ubiquitous chromatin regulatory structures in the human genome.
-
Identification and characterization of the human parkin gene promoter.
-
Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection.
-
Identification and developmental expression of two activin receptors in baboon lung.
-
Identification and expression analysis of spastin gene mutations in hereditary spastic paraplegia.
-
Identification and functional characterization of a high-affinity Bel-1 DNA binding site located in the human foamy virus internal promoter.
-
Identification and functional characterization of the human glutathione S-transferase P1 gene as a novel transcriptional target of the p53 tumor suppressor gene.
-
Identification and mapping of type 1 neurofibromatosis (NF1) homologous loci.
-
Identification and sequence of the initiation site for rat 45S ribosomal RNA synthesis.
-
Identification of E2A target genes in B lymphocyte development by using a gene tagging-based chromatin immunoprecipitation system.
-
Identification of IGFBP-6 as a significantly downregulated gene by beta-catenin in desmoid tumors.
-
Identification of JWA as a novel functional gene responsive to environmental oxidative stress induced by benzo[a]pyrene and hydrogen peroxide.
-
Identification of STRA6 and SKI sequence variants in patients with anophthalmia/microphthalmia.
-
Identification of a 41 kDa protein embedded in the biosilica of scales and bristles isolated from Mallomonas splendens (Synurophyceae)
-
Identification of a Cryptococcus neoformans gene that directs expression of the cryptic Saccharomyces cerevisiae mannitol dehydrogenase gene.
-
Identification of a U5-specific sequence required for efficient polyadenylation within the human immunodeficiency virus long terminal repeat.
-
Identification of a brain- and reproductive-organs-specific gene responsive to DNA damage and retinoic acid.
-
Identification of a cleavage site directing the immunochemical detection of molecular abnormalities in type IIA von Willebrand factor.
-
Identification of a critical regulatory site in the human interleukin-3 promoter by in vivo footprinting.
-
Identification of a distinctive mutation spectrum associated with high levels of transcription in yeast.
-
Identification of a fetal exon in the human fast troponin T gene.
-
Identification of a high-affinity RNA-binding site for the human immunodeficiency virus type 1 Rev protein.
-
Identification of a muscle-specific enhancer within the 5'-flanking region of the human myoglobin gene.
-
Identification of a negative regulatory element involved in tissue-specific expression of mouse renin genes.
-
Identification of a new family of protein phosphatase 2A regulatory subunits.
-
Identification of a new mutation in medium-chain acyl-CoA dehydrogenase (MCAD) deficiency.
-
Identification of a new subclass of Alu DNA repeats which can function as estrogen receptor-dependent transcriptional enhancers.
-
Identification of a new variant of PDE1A calmodulin-stimulated cyclic nucleotide phosphodiesterase expressed in mouse sperm.
-
Identification of a nonsense mutation at codon 128 of the Norrie's disease gene in a male infant.
-
Identification of a novel gene linked to parkin via a bi-directional promoter.
-
Identification of a p28 gene in Ehrlichia ewingii: evaluation of gene for use as a target for a species-specific PCR diagnostic assay.
-
Identification of a putative Salmonella enterica serotype typhimurium host range factor with homology to IpaH and YopM by signature-tagged mutagenesis.
-
Identification of a rat glomerular mesangial cell mitogenic 5-HT2A receptor.
-
Identification of a region of genetic variability among Bacillus anthracis strains and related species.
-
Identification of a strand-related bias in the PCNA-mediated bypass of spontaneous lesions by yeast Poleta.
-
Identification of a structurally distinct CD101 molecule encoded in the 950-kb Idd10 region of NOD mice.
-
Identification of additional members of human G-protein-coupled receptor kinase multigene family.
-
Identification of amino acid residues involved in structural and ubiquinone-binding functions of subunit IV of the cytochrome bc1 complex from Rhodobacter sphaeroides.
-
Identification of an alternate promoter in the rat androgen-binding protein/sex hormone-binding globulin gene that regulates synthesis of a messenger RNA encoding a protein with altered function.
-
Identification of an enhancer element in the estrogen receptor upstream region: implications for regulation of ER transcription in breast cancer.
-
Identification of an essential site for transcriptional activation within the human T-cell receptor delta enhancer.
-
Identification of an estrogen response element in the 3'-flanking region of the murine c-fos protooncogene.
-
Identification of asteroid genera with species capable of larval cloning.
-
Identification of cis elements directing termination of yeast nonpolyadenylated snoRNA transcripts.
-
Identification of clinical strains of Candida albicans by DNA fingerprinting with the polymerase chain reaction.
-
Identification of endothelin-1 in the pathophysiology of metastatic adenocarcinoma of the prostate.
-
Identification of liver cancer-specific aptamers using whole live cells.
-
Identification of multiple species of calmodulin messenger RNA using a full length complementary DNA.
-
Identification of negative and positive regulatory elements in the human renin gene.
-
Identification of new mamu-DRB alleles using DGGE and direct sequencing.
-
Identification of novel hrp-regulated genes through functional genomic analysis of the Pseudomonas syringae pv. tomato DC3000 genome.
-
Identification of novel mutations in the proton-coupled folate transporter (PCFT-SLC46A1) associated with hereditary folate malabsorption.
-
Identification of novel steroid-response elements.
-
Identification of prohibitin and prohibiton as novel factors binding to the p53 induced gene 3 (PIG3) promoter (TGYCC)(15) motif.
-
Identification of putative human T cell receptor delta complementary DNA clones.
-
Identification of renin and angiotensinogen messenger RNA sequences in mouse and rat brains.
-
Identification of the MATa mating-type locus of Cryptococcus neoformans reveals a serotype A MATa strain thought to have been extinct.
-
Identification of the breast cancer susceptibility gene BRCA2.
-
Identification of the promoter region of the human betaIGH3 gene.
-
Identification of the ral and rac1 gene products, low molecular mass GTP-binding proteins from human platelets.
-
Identification of the same factor V gene mutation in 47 out of 50 thrombosis-prone families with inherited resistance to activated protein C.
-
Identification of the single base change causing the callipyge muscle hypertrophy phenotype, the only known example of polar overdominance in mammals.
-
Identification of the yeast cytidine deaminase CDD1 as an orphan C-->U RNA editase.
-
Identification of ubiquitination sites on the X-linked inhibitor of apoptosis protein.
-
Identification of variants in CNGA3 as cause for achromatopsia by exome sequencing of a single patient.
-
Identification of viral microRNAs expressed in human sacral ganglia latently infected with herpes simplex virus 2.
-
Identification of yeast mutants with altered telomere structure.
-
Identification, characterization, and ontogeny of a second cytochrome P450 3A gene from the fresh water teleost medaka (Oryzias latipes).
-
Identification, chromosomal mapping and tissue-specific expression of hREV3 encoding a putative human DNA polymerase zeta.
-
Identification, cloning, and expression of a cytosolic megakaryocyte protein-tyrosine-phosphatase with sequence homology to cytoskeletal protein 4.1.
-
Identification, cloning, and expression of the Escherichia coli pyrazinamidase and nicotinamidase gene, pncA.
-
Identification, molecular cloning, and mutagenesis of Saccharomyces cerevisiae RNA polymerase genes.
-
Identification, purification, and characterization of GRK5, a member of the family of G protein-coupled receptor kinases.
-
Identifying a transcription factor interaction site on RNA polymerase II.
-
Ig VH hypermutation is absent in the germinal centers of aged mice.
-
Immobilized molecular beacons: a new strategy using UV-activated poly(methyl methacrylate) surfaces to provide large fluorescence sensitivities for reporting on molecular association events.
-
Immune evasion by murine melanoma mediated through CC chemokine receptor-10.
-
Immune response to p53 is dependent upon p53/HSP70 complexes in breast cancers.
-
Immunity to MHC class I antigen after direct DNA transfer into skeletal muscle.
-
Immunochemical and molecular analysis of antigen binding to lipid anchored and soluble forms of an MHC independent human alpha/beta T cell receptor.
-
Immunophilins interact with calcineurin in the absence of exogenous immunosuppressive ligands.
-
Immunoselection of cDNAs to avian intestinal calcium binding protein 28K and a novel calmodulin-like protein: assessment of mRNA regulation by the vitamin D hormone.
-
Impact of immune escape mutations on HIV-1 fitness in the context of the cognate transmitted/founder genome.
-
Impact of static and dynamic A-form heterogeneity on the determination of RNA global structural dynamics using NMR residual dipolar couplings.
-
Impaired cytoskeletal organization and membrane integrity in lens fibers of a Rho GTPase functional knockout transgenic mouse.
-
Impaired degranulation but enhanced cytokine production after Fc epsilonRI stimulation of diacylglycerol kinase zeta-deficient mast cells.
-
Impaired expression and functional activity of the beta 3- and beta 1-adrenergic receptors in adipose tissue of congenitally obese (C57BL/6J ob/ob) mice.
-
Impaired immune responses and B-cell proliferation in mice lacking the Id3 gene.
-
Implementing a cumulative supermatrix approach for a comprehensive phylogenetic study of the Teloschistales (Pezizomycotina, Ascomycota).
-
Importance sampling for the infinite sites model.
-
Imprinting of PEG3, the human homologue of a mouse gene involved in nurturing behavior.
-
Improved antitumor activity of a recombinant anti-Lewis(y) immunotoxin not requiring proteolytic activation.
-
Improved non-chromatographic purification of a recombinant protein by cationic elastin-like polypeptides.
-
Improvements to the differential display method for gene analysis.
-
In situ distinction between steroid receptor binding and transactivation at a target gene.
-
In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populations.
-
In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. II. A common clonal origin for periarteriolar lymphoid sheath-associated foci and germinal centers.
-
In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. III. The kinetics of V region mutation and selection in germinal center B cells.
-
In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. IV. Affinity-dependent, antigen-driven B cell apoptosis in germinal centers as a mechanism for maintaining self-tolerance.
-
In vitro RNA selection identifies RNA ligands that specifically bind to eukaryotic translation initiation factor 4B: the role of the RNA remotif.
-
In vitro RNA selection of an autoimmune epitope on stem-loop II of U1 RNA.
-
In vitro and in vivo behavior of radiolabeled chimeric anti-EGFRvIII monoclonal antibody: comparison with its murine parent.
-
In vitro maturation of circular bacteriophage P2 DNA. Purification of ter components and characterization of the reaction.
-
In vitro selection of DNA elements highly responsive to the human T-cell lymphotropic virus type I transcriptional activator, Tax.
-
In vitro selection of RNA epitopes using autoimmune patient serum.
-
In vitro selection of an RNA epitope immunologically cross-reactive with a peptide.
-
In vitro transcriptional studies of the roles of the thyroid hormone (T3) response elements and minimal promoters in T3-stimulated gene transcription.
-
In vivo footprinting of the human alpha-globin locus upstream regulatory element by guanine and adenine ligation-mediated polymerase chain reaction.
-
In vivo functional analysis of in vitro protein binding sites in the immunoglobulin heavy chain enhancer.
-
In vivo genetic variability of the human immunodeficiency virus type 2 V3 region.
-
In vivo hypermutation of xenotropic murine leukemia virus-related virus DNA in peripheral blood mononuclear cells of rhesus macaque by APOBEC3 proteins.
-
In vivo identification of a negative regulatory element in the mouse renin gene using direct gene transfer.
-
In vivo modulation of 17 beta-estradiol-induced vitellogenin synthesis and estrogen receptor in rainbow trout (Oncorhynchus mykiss) liver cells by beta-naphthoflavone.
-
In vivo mutagenesis of the reporter plasmid pSP189 induced by exposure of host Ad293 cells to activated polymorphonuclear leukocytes.
-
In vivo transfer of GPI-linked complement restriction factors from erythrocytes to the endothelium.
-
In-depth analysis of Kaposi's sarcoma-associated herpesvirus microRNA expression provides insights into the mammalian microRNA-processing machinery.
-
In-vivo studies on the cis-acting replication initiator protein of IncFII plasmid NR1.
-
Inactivated whole-virus vaccine derived from a proviral DNA clone of simian immunodeficiency virus induces high levels of neutralizing antibodies and confers protection against heterologous challenge.
-
Inactivation of the MAL gene in breast cancer is a common event that predicts benefit from adjuvant chemotherapy.
-
Inactivation of the human papillomavirus E6 or E7 gene in cervical carcinoma cells by using a bacterial CRISPR/Cas RNA-guided endonuclease.
-
IncFII plasmid incompatibility product and its target are both RNA transcripts.
-
Incompatibility and IncFII plasmid replication control.
-
Incongruence between primary sequence data and the distribution of a mitochondrial atp1 group II intron among ferns and horsetails
-
Incorporation of CC steps into Z-DNA: interplay between B-Z junction and Z-DNA helical formation.
-
Increased expression of Drosophila tetraspanin, Tsp68C, suppresses the abnormal proliferation of ytr-deficient and Ras/Raf-activated hemocytes.
-
Increased p53 protein does not correlate to p53 gene mutations in microdissected human testicular germ cell tumors.
-
Increased transversions in a novel mutator colon cancer cell line.
-
Independent ancient polyploidy events in the sister families Brassicaceae and Cleomaceae.
-
Independent beta-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2.
-
Independent variation and positive selection in env V1 and V2 domains within maternal-infant strains of human immunodeficiency virus type 1 in vivo.
-
Independently derived murine glomerular immune deposit-forming anti-DNA antibodies are encoded by near-identical VH gene sequences.
-
Indistinguishable nuclear factor binding to functional core sites of the T-cell receptor delta and murine leukemia virus enhancers.
-
Induction of a human carbonyl reductase gene located on chromosome 21.
-
Induction of cyclooxygenase-2 in human endometrial stromal cells by malignant endometrial epithelial cells: evidence for the involvement of extracellularly regulated kinases and CCAAT/enhancer binding proteins.
-
Induction of internucleosomal DNA fragmentation by carcinogenic chromate: relationship to DNA damage, genotoxicity, and inhibition of macromolecular synthesis.
-
Induction of nitric oxide synthase in demyelinating regions of multiple sclerosis brains.
-
Induction of potent humoral and cell-mediated immune responses following direct injection of DNA encoding the HIV type 1 env and rev gene products.
-
Induction of stress proteins in cultured myogenic cells. Molecular signals for the activation of heat shock transcription factor during ischemia.
-
Influence of dimethylsulfoxide on RNA structure and ligand binding.
-
Informative priors based on transcription factor structural class improve de novo motif discovery.
-
Infrequent RAS oncogene mutations in human prostate cancer.
-
Inherited human complement C5 deficiency. Nonsense mutations in exons 1 (Gln1 to Stop) and 36 (Arg1458 to Stop) and compound heterozygosity in three African-American families.
-
Inhibition of G protein-coupled receptor signaling by expression of cytoplasmic domains of the receptor.
-
Inhibition of Rev activity and human immunodeficiency virus type 1 replication by antisense oligodeoxynucleotide phosphorothioate analogs directed against the Rev-responsive element.
-
Inhibition of T cell costimulation by VCAM-1 prevents murine graft-versus-host disease across minor histocompatibility barriers.
-
Inhibition of cell proliferation by an RNA ligand that selectively blocks E2F function.
-
Inhibition of gastric cancer invasion and metastasis by PLA2G2A, a novel beta-catenin/TCF target gene.
-
Inhibition of growth of human malignant glioblastoma in nude mice by antagonists of bombesin/gastrin-releasing peptide.
-
Inhibition of nitric oxide synthesis increases mortality in Sindbis virus encephalitis.
-
Inhibition of rat corneal angiogenesis by a nuclease-resistant RNA aptamer specific for angiopoietin-2.
-
Inhibition of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase pathway induces p53-independent transcriptional regulation of p21(WAF1/CIP1) in human prostate carcinoma cells.
-
Inhibition of the erbB-2 tyrosine kinase receptor in breast cancer cells by phosphoromonothioate and phosphorodithioate antisense oligonucleotides.
-
Initiation of methyl-directed mismatch repair.
-
Inositol phosphate multikinase dependent transcriptional control.
-
Inositol polyphosphate 1-phosphatase is present in the nucleus and inhibits DNA synthesis.
-
Insights from a chimpanzee adipose stromal cell population: opportunities for adult stem cells to expand primate functional genomics.
-
Insights from the first putative biosynthetic gene cluster for a lichen depside and depsidone.
-
Insights into evolution of multicellular fungi from the assembled chromosomes of the mushroom Coprinopsis cinerea (Coprinus cinereus).
-
Instability of a plasmid-borne inverted repeat in Saccharomyces cerevisiae.
-
Instability of simple sequence DNA in Saccharomyces cerevisiae.
-
Instability of simple sequence repeats in a mammalian cell line.
-
Integrating ambiguously aligned regions of DNA sequences in phylogenetic analyses without violating positional homology.
-
Integration of DNA fragments by illegitimate recombination in Saccharomyces cerevisiae.
-
Integration specificities of two lambdoid phages (21 and e14) that insert at the same attB site.
-
Integrative analysis identifies targetable CREB1/FoxA1 transcriptional co-regulation as a predictor of prostate cancer recurrence.
-
Interaction between the Ah receptor and proteins binding to the AP-1-like electrophile response element (EpRE) during murine phase II [Ah] battery gene expression.
-
Interaction of dihydrofolate reductase with methotrexate: ensemble and single-molecule kinetics.
-
Interaction of plasminogen with dipeptidyl peptidase IV initiates a signal transduction mechanism which regulates expression of matrix metalloproteinase-9 by prostate cancer cells.
-
Interaction of the regulatory domains of the murine Cyp1a1 gene with two DNA-binding proteins in addition to the Ah receptor and the Ah receptor nuclear translocator (ARNT).
-
Interactions between small viral RNAs of vesicular stomatitis virus and components of cellular gene expression.
-
Interactions of TLC1 (which encodes the RNA subunit of telomerase), TEL1, and MEC1 in regulating telomere length in the yeast Saccharomyces cerevisiae.
-
Interactions of plus and minus strand leader RNAs of the New Jersey serotype of vesicular stomatitis virus with the cellular La protein.
-
Interferon gamma (IFNgamma) gene transfer of an EMT6 tumor that is poorly responsive to IFNgamma stimulation: increase in tumor immunogenicity is accompanied by induction of a mouse class II transactivator and class II MHC.
-
Interferon regulatory factors are transcriptional regulators of adipogenesis.
-
Interferon regulatory factors regulate interleukin-1beta-converting enzyme expression and apoptosis in vascular smooth muscle cells.
-
Interleukin 12 at the site of disease in tuberculosis.
-
Interleukin-1 stimulates the beta-amyloid precursor protein promoter.
-
Interleukin-3 expression by activated T cells involves an inducible, T-cell-specific factor and an octamer binding protein.
-
Interleukin-6 induces hepcidin expression through STAT3.
-
Internal ribosomal entry site substitution eliminates neurovirulence in intergeneric poliovirus recombinants.
-
Internalization of fibroblast growth factor receptor is inhibited by a point mutation at tyrosine 766.
-
Interplay of the Arabidopsis nonhost resistance gene NHO1 with bacterial virulence.
-
Interrupter sequences that are widely distributed in the Drosophila genome.
-
Intervening sequence between the leader region and the nucleopcapsid gene of vesicular stomatitis virus RNA.
-
Intestinal apolipoprotein AI gene transcription is regulated by multiple distinct DNA elements and is synergistically activated by the orphan nuclear receptor, hepatocyte nuclear factor 4.
-
Intestinal transcription and synthesis of apolipoprotein AI is regulated by five natural polymorphisms upstream of the apolipoprotein CIII gene.
-
Intimal hyperplasia after vascular injury is inhibited by antisense cdk 2 kinase oligonucleotides.
-
Intracerebral cytokine mRNA expression during fatal and nonfatal alphavirus encephalitis suggests a predominant type 2 T cell response.
-
Intrachromosomal gene conversion and the maintenance of sequence homogeneity among repeated genes.
-
Intraclonal generation of antibody mutants in germinal centres.
-
Intrinsic activity of human immunodeficiency virus type 1 protease heterologous fusion proteins in mammalian cells.
-
Intron retention in mRNA encoding ancillary subunit of insect voltage-gated sodium channel modulates channel expression, gating regulation and drug sensitivity.
-
Intronic deletions in the SLC34A3 gene cause hereditary hypophosphatemic rickets with hypercalciuria.
-
Investigation of the phenylethanolamine N-methyltransferase gene as a candidate gene for hypertension.
-
Involvement of a cytosine side chain in proton transfer in the rate-determining step of ribozyme self-cleavage.
-
Involvement of outside DNA sequences in the major kinetic path by which EcoRI endonuclease locates and leaves its recognition sequence.
-
Involvement of p72syk kinase, p53/56lyn kinase and phosphatidyl inositol-3 kinase in signal transduction via the human B lymphocyte antigen CD22.
-
Involvement of the TCL5 gene on human chromosome 1 in T-cell leukemia and melanoma.
-
Is the aneuploid chromosome in an apomictic Boechera holboellii a genuine B chromosome?
-
Is there left-handed DNA at the ends of yeast chromosomes?
-
Isolated sulfite oxidase deficiency.
-
Isolation and analysis of cDNA clones expressing human lupus La antigen.
-
Isolation and biochemical characterization of LEAP-2, a novel blood peptide expressed in the liver.
-
Isolation and characterization of a Ty element inserted into the ribosomal DNA of the yeast Saccharomyces cerevisiae.
-
Isolation and characterization of a dual-substrate phosphodiesterase gene family: PDE10A.
-
Isolation and characterization of a human pro alpha 2(I) collagen gene segment.
-
Isolation and characterization of a mouse homolog of the Drosophila segment polarity gene dishevelled.
-
Isolation and characterization of a new chemokine receptor gene, the putative chicken CXCR1.
-
Isolation and characterization of cDNA clones encoding pig gastric mucin.
-
Isolation and characterization of cDNAs encoding human brain ankyrins reveal a family of alternatively spliced genes.
-
Isolation and characterization of cul1-7, a recessive allele of CULLIN1 that disrupts SCF function at the C terminus of CUL1 in Arabidopsis thaliana.
-
Isolation and characterization of human casein kinase I epsilon (CKI), a novel member of the CKI gene family.
-
Isolation and characterization of the CYP71D16 trichome-specific promoter from Nicotiana tabacum L.
-
Isolation and characterization of the Escherichia coli mutH gene product.
-
Isolation and characterization of the gene encoding rat glucose-dependent insulinotropic peptide.
-
Isolation and characterization of the genomic human CD7 gene: structural similarity with the murine Thy-1 gene.
-
Isolation and characterization of the rat chromosomal gene for a polypeptide (pS1) antigenically related to statin.
-
Isolation and characterization of the replicon of a Thiobacillus intermedius plasmid.
-
Isolation and chromosomal localization of cDNAs encoding a novel human lymphocyte cell surface molecule, LAM-1. Homology with the mouse lymphocyte homing receptor and other human adhesion proteins.
-
Isolation and functional analysis of the mouse RXRgamma1 gene promoter in anterior pituitary cells.
-
Isolation and heterologous expression of a cDNA encoding bovine inositol polyphosphate 1-phosphatase.
-
Isolation and initial characterization of the 5' flanking region of the human and murine cyclic guanosine monophosphate-phosphodiesterase beta-subunit genes.
-
Isolation and initial characterization of the BRCA2 promoter.
-
Isolation and nucleotide sequence of canine glucose-6-phosphatase mRNA: identification of mutation in puppies with glycogen storage disease type Ia.
-
Isolation and nucleotide sequence of human liver glycogen debranching enzyme mRNA: identification of multiple tissue-specific isoforms.
-
Isolation and structural analysis of the chromosomal gene for chicken calmodulin.
-
Isolation and structure of a cDNA encoding the B1 (CD20) cell-surface antigen of human B lymphocytes.
-
Isolation of Vgr-2, a novel member of the transforming growth factor-beta-related gene family.
-
Isolation of a cDNA clone complementary to sequences for a 34-kilodalton protein which is a pp60v-src substrate.
-
Isolation of a cDNA clone for the alpha subunit of the human GABA-A receptor.
-
Isolation of a diverged homeobox gene, MOX1, from the BRCA1 region on 17q21 by solution hybrid capture.
-
Isolation of a functional human gene for brain creatine kinase.
-
Isolation of a nuclease-resistant decoy RNA that can protect human acetylcholine receptors from myasthenic antibodies.
-
Isolation of a nuclease-resistant decoy RNA that selectively blocks autoantibody binding to insulin receptors on human lymphocytes.
-
Isolation of a rat parvalbumin gene and full length cDNA.
-
Isolation of an hMSH2-p160 heterodimer that restores DNA mismatch repair to tumor cells.
-
Isolation of cDNAs encoding the CD19 antigen of human and mouse B lymphocytes. A new member of the immunoglobulin superfamily.
-
Isolation of human sequences that replicate autonomously in human cells.
-
Isolation of the structural gene for calmodulin.
-
Isolation of two E-box binding factors that interact with the rat tyrosine hydroxylase enhancer.
-
Isolation, characterization, and cDNA cloning of a vampire bat salivary plasminogen activator.
-
JNK activation decreases PP2A regulatory subunit B56alpha expression and mRNA stability and increases AUF1 expression in cardiomyocytes.
-
K+ regulates DNA binding of transcription factors to control gene expression related to neuronal apoptosis.
-
K12/SECTM1, an interferon-γ regulated molecule, synergizes with CD28 to costimulate human T cell proliferation.
-
Kallikrein-related mRNAs of the rat submaxillary gland: nucleotide sequences of four distinct types including tonin.
-
Kaposi's sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cells.
-
Kindling induces the long-lasting expression of a novel population of NMDA receptors in hippocampal region CA3.
-
Kinetic mechanism of adenine phosphoribosyltransferase from Leishmania donovani.
-
Kinetic mechanism of the DNA-dependent DNA polymerase activity of human immunodeficiency virus reverse transcriptase.
-
Kinetics of expression of multiply spliced RNA in early human immunodeficiency virus type 1 infection of lymphocytes and monocytes.
-
Kinetics of expression of multiply spliced RNA in early human immunodeficiency virus type 1 infection of lymphocytes and monocytes.
-
Kinetics of human immunodeficiency virus type 1 (HIV-1) DNA and RNA synthesis during primary HIV-1 infection.
-
Knock-in mutation of the distal four tyrosines of linker for activation of T cells blocks murine T cell development.
-
Knocking down type 2 but not type 1 calsequestrin reduces calcium sequestration and release in C2C12 skeletal muscle myotubes.
-
Knockout of Nr2e3 prevents rod photoreceptor differentiation and leads to selective L-/M-cone photoreceptor degeneration in zebrafish.
-
Kupffer cell depletion abolishes induction of interleukin-10 and permits sustained overexpression of tumor necrosis factor alpha messenger RNA in the regenerating rat liver.
-
Kupffer cell depletion by gadolinium chloride enhances liver regeneration after partial hepatectomy in rats.
-
LFA-1 binding site in ICAM-3 contains a conserved motif and non-contiguous amino acids.
-
LMNA, encoding lamin A/C, is mutated in partial lipodystrophy.
-
LOC387715/HTRA1 and complement factor H variants in patients with age-related macular degeneration seen at the mayo clinic.
-
LXRalpha functions as a cAMP-responsive transcriptional regulator of gene expression.
-
Landscape position influences microbial composition and function via redistribution of soil water across a watershed.
-
Learning new tricks from old dogs: beta-adrenergic receptors teach new lessons on firing up adipose tissue metabolism.
-
Lethal-7 is down-regulated by the hepatitis B virus x protein and targets signal transducer and activator of transcription 3.
-
Lewy body and Alzheimer pathology in a family with the amyloid-beta precursor protein APP717 gene mutation.
-
LexA protein of Escherichia coli represses expression of the Tn5 transposase gene.
-
Ligand-induced conformational changes in a thermophilic ribose-binding protein.
-
Ligand-induced recruitment of a histone deacetylase in the negative-feedback regulation of the thyrotropin beta gene.
-
Light-inducible gene regulation with engineered zinc finger proteins.
-
Limits in the detection of m6A changes using MeRIP/m6A-seq.
-
Linkage disequilibrium at the Angelman syndrome gene UBE3A in autism families.
-
Linkage mapping of the angiotensin AT2 receptor gene (Agtr2) to the mouse X chromosome.
-
Linkage of 'pure' autosomal recessive familial spastic paraplegia to chromosome 8 markers and evidence of genetic locus heterogeneity.
-
Lipid levels are associated with a regulatory polymorphism of the monoamine oxidase-A gene promoter (MAOA-uVNTR).
-
Liver X receptors alpha and beta regulate renin expression in vivo.
-
LncRNA wires up Hippo and Hedgehog signaling to reprogramme glucose metabolism.
-
Localization of RAP1 and topoisomerase II in nuclei and meiotic chromosomes of yeast.
-
Localization of a retroviral element within the rd gene coding for the beta subunit of cGMP phosphodiesterase.
-
Localization of alpha 2-adrenergic receptor subtypes in the anterior segment of the human eye with selective antibodies.
-
Localization of an aminoacridine antitumor agent in a type II topoisomerase-DNA complex.
-
Localization of the VHR phosphatase gene and its analysis as a candidate for BRCA1.
-
Location of the 5.8S rRNA gene of Saccharomyces cerevisiae.
-
Location of the host attachment site for phage HPl within a cluster of Haemophilus influenzae tRNA genes.
-
Locus-specific somatic hypermutation in germinal centre T cells.
-
Long contiguous stretches of homozygosity in the human genome.
-
Long poly(A) tracts in the human genome are associated with the Alu family of repeated elements.
-
Long-term exposure of chemokine CXCL10 causes bronchiolitis-like inflammation.
-
Loss of EGFR signaling regulated miR-203 promotes prostate cancer bone metastasis and tyrosine kinase inhibitors resistance.
-
Loss of chromosome 8p sequences in human breast carcinoma cell lines.
-
Low prevalence of Pneumocystis pneumonia (PCP) but high prevalence of pneumocystis dihydropteroate synthase (dhps) gene mutations in HIV-infected persons in Uganda.
-
Low-copy nuclear sequence data confirm complex patterns of farina evolution in notholaenid ferns (Pteridaceae)
-
Lung EC-SOD overexpression attenuates hypoxic induction of Egr-1 and chronic hypoxic pulmonary vascular remodeling.
-
Lupus autoantibodies recognize the product of an alternative open reading frame of SmB/B'.
-
LvTbx2/3, a T-box Family Transcription Factor Involved in Formation of the Oral/Aboral Axis of the Sea Urchin Embryo
-
M6P/IGF2 receptor: a candidate breast tumor suppressor gene.
-
MAGE-1-specific precursor cytotoxic T-lymphocytes present among tumor-infiltrating lymphocytes from a patient with breast cancer: characterization and antigen-specific activation.
-
MEF2 responds to multiple calcium-regulated signals in the control of skeletal muscle fiber type.
-
MGSA/GRO transcription is differentially regulated in normal retinal pigment epithelial and melanoma cells.
-
MOP2 (SLA2) affects the abundance of the plasma membrane H(+)-ATPase of Saccharomyces cerevisiae.
-
MPDA: microarray pooled DNA analyzer.
-
MSH6, a Saccharomyces cerevisiae protein that binds to mismatches as a heterodimer with MSH2.
-
MSIseq: Software for Assessing Microsatellite Instability from Catalogs of Somatic Mutations.
-
MYC Disrupts the Circadian Clock and Metabolism in Cancer Cells.
-
Maintenance of G2 arrest in the Xenopus oocyte: a role for 14-3-3-mediated inhibition of Cdc25 nuclear import.
-
Maintenance of p53 alterations throughout breast cancer progression.
-
Major histocompatibility complex variation and evolution at a single, expressed DQA locus in two genera of elephants.
-
Malaria severity and human nitric oxide synthase type 2 (NOS2) promoter haplotypes.
-
Malignant breast epithelial cells stimulate aromatase expression via promoter II in human adipose fibroblasts: an epithelial-stromal interaction in breast tumors mediated by CCAAT/enhancer binding protein beta.
-
Mammalian RAFT1 kinase domain provides rapamycin-sensitive TOR function in yeast.
-
Mammalian dwarfins are phosphorylated in response to transforming growth factor beta and are implicated in control of cell growth.
-
Mammalian homologs of Drosophila ELAV localized to a neuronal subset can bind in vitro to the 3' UTR of mRNA encoding the Id transcriptional repressor.
-
Manipulation of OCT4 levels in human embryonic stem cells results in induction of differential cell types.
-
Many globally isolated AD hybrid strains of Cryptococcus neoformans originated in Africa.
-
Mapping mutations in genes encoding the two large subunits of Drosophila RNA polymerase II defines domains essential for basic transcription functions and for proper expression of developmental genes.
-
Mapping of copper/hydrogen peroxide-induced DNA damage at nucleotide resolution in human genomic DNA by ligation-mediated polymerase chain reaction.
-
Mapping of ionomic traits in Mimulus guttatus reveals Mo and Cd QTLs that colocalize with MOT1 homologues.
-
Mapping of peroxyl radical induced damage on genomic DNA.
-
Mapping of rRNA genes with integrable plasmids in Bacillus subtilis.
-
Mapping of the mouse Rxr loci encoding nuclear retinoid X receptors RXR alpha, RXR beta, and RXR gamma.
-
Mapping of transcription start sites in Saccharomyces cerevisiae using 5' SAGE.
-
Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments.
-
Marker rescue of adeno-associated virus (AAV) capsid mutants: a novel approach for chimeric AAV production.
-
Marrow cell transplantation for infantile hypophosphatasia.
-
Mass spectrometry of nucleic acids: the promise of matrix-assisted laser desorption-ionization (MALDI) mass spectrometry.
-
Matroshka and ectopic polymorphisms: Two new classes of DNA sequence variation identified at the Van der Woude syndrome locus on 1q32-q41.
-
Measuring spatial preferences at fine-scale resolution identifies known and novel cis-regulatory element candidates and functional motif-pair relationships.
-
Measuring thermodynamic preferences to form non-native conformations in nucleic acids using ultraviolet melting.
-
Mechanical Stability of a Small, Highly-Luminescent Engineered Protein NanoLuc.
-
Mechanism of action of regulatory proteins encoded by complex retroviruses.
-
Mechanism of activation of simian virus 40 DNA replication by protein phosphatase 2A.
-
Mechanism of inactivation of CDKN2 and MTS2 in non-small cell lung cancer and association with advanced stage.
-
Mechanism of specific site location and DNA cleavage by EcoR I endonuclease.
-
Mechanisms for dominance: Adh heterodimer formation in heterozygotes between ENU or X-ray induced null alleles and normal alleles in Drosophila melanogaster.
-
Mechanisms of immune stimulation by bacterial DNA.
-
Mechanistic insights into cancer cell killing through interaction of phosphodiesterase 3A and schlafen family member 12.
-
Mediation of meiotic and early mitotic chromosome segregation in Drosophila by a protein related to kinesin.
-
Medium-chain acyl-CoA dehydrogenase deficiency: postmortem diagnosis in a case of sudden infant death and neonatal diagnosis of an affected sibling.
-
Meiotic recombination within the centromere of a yeast chromosome.
-
Membrane localization and topology of a viral assembly protein.
-
Membranomyces species are common ectomycorrhizal symbionts in Northern Hemisphere forests
-
Mesenchymal stem cells differentiate into renin-producing juxtaglomerular (JG)-like cells under the control of liver X receptor-alpha.
-
Messenger RNA intron in the nuclear 18s ribosomal RNA gene of deuteromycetes.
-
Messenger RNAs of a strongly-expressed late gene of cowpox virus contain 5'-terminal poly(A) sequences.
-
Metabolites from apoptotic thymocytes inhibit thymopoiesis in adenosine deaminase-deficient fetal thymic organ cultures.
-
Methyl-directed mismatch repair is bidirectional.
-
Methyl-directed repair of DNA base-pair mismatches in vitro.
-
Mice with a deletion in the gene for CCAAT/enhancer-binding protein beta are protected against diet-induced obesity.
-
Mice with alopecia, osteoporosis, and systemic amyloidosis due to mutation in Zdhhc13, a gene coding for palmitoyl acyltransferase.
-
Mice with duplications and deletions at the Tme locus have altered MnSOD activity.
-
Micro-RNA-181a regulates osteopontin-dependent metastatic function in hepatocellular cancer cell lines.
-
MicroRNA antagonism of the picornaviral life cycle: alternative mechanisms of interference.
-
MicroRNA-29 is an essential regulator of brain maturation through regulation of CH methylation.
-
MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms.
-
MicroRNAs both promote and antagonize longevity in C. elegans.
-
MicroRNAs expressed by herpes simplex virus 1 during latent infection regulate viral mRNAs.
-
Microcytic anemia in mk/mk mice is not corrected by retroviral-mediated gene transfer of wild-type p45 NF-E2.
-
Microsatellite variation in populations of Drosophila pseudoobscura and Drosophila persimilis.
-
Migraine with aura susceptibility locus on chromosome 19p13 is distinct from the familial hemiplegic migraine locus.
-
Minimal and inducible regulation of tissue factor pathway inhibitor-2 in human gliomas.
-
Minimal phenotype of mice homozygous for a null mutation in the forkhead/winged helix gene, Mf2.
-
Misincorporation and mispaired primer extension by human immunodeficiency virus reverse transcriptase.
-
Mismatch repair and genetic stability in human cells.
-
Mismatch repair deficiency in phenotypically normal human cells.
-
Mismatch repair proteins regulate heteroduplex formation during mitotic recombination in yeast.
-
Mismatch repair-dependent iterative excision at irreparable O6-methylguanine lesions in human nuclear extracts.
-
Mismatch-, MutS-, MutL-, and helicase II-dependent unwinding from the single-strand break of an incised heteroduplex.
-
Mispair specificity of methyl-directed DNA mismatch correction in vitro.
-
Missense mutation (G480C) in the CFTR gene associated with protein mislocalization but normal chloride channel activity.
-
Missing genetic risk in neural tube defects: can exome sequencing yield an insight?
-
Mitochondrial DNA sequence associations with dementia and amyloid-β in elderly African Americans.
-
Mitochondrial DNA sequence variation associated with dementia and cognitive function in the elderly.
-
Mitochondrial DNA structure and expression in specialized subtypes of mammalian striated muscle.
-
Mitochondrial biogenesis in striated muscles: rapid induction of citrate synthase mRNA by nerve stimulation.
-
Mitochondrial transcription factor A induction by redox activation of nuclear respiratory factor 1.
-
Mitotic crossovers between diverged sequences are regulated by mismatch repair proteins in Saccaromyces cerevisiae.
-
Mode of Action of a Designed Antimicrobial Peptide: High Potency against Cryptococcus neoformans.
-
Modeling in yeast how rDNA introns slow growth and increase desiccation tolerance in lichens.
-
Modeling the evolution of regulatory elements by simultaneous detection and alignment with phylogenetic pair HMMs.
-
Modification of depression by COMT val158met polymorphism in children exposed to early severe psychosocial deprivation.
-
Modular, well-behaved reversible polymers from DNA-based monomers.
-
Modulation of glutathione peroxidase expression by selenium: effect on human MCF-7 breast cancer cell transfectants expressing a cellular glutathione peroxidase cDNA and doxorubicin-resistant MCF-7 cells.
-
Modulation of ligand binding affinity of the adipocyte lipid-binding protein by selective mutation. Analysis in vitro and in situ.
-
Modulation of oncogene and tumor suppressor gene expression in a hamster model of chronic lung injury with varying degrees of pulmonary neuroendocrine cell hyperplasia.
-
Modulation of progesterone receptor binding to progesterone response elements by positioned nucleosomes.
-
Modulation of utrophin A mRNA stability in fast versus slow muscles via an AU-rich element and calcineurin signaling.
-
Modulatory function of CREB.CREM alpha heterodimers depends upon CREM alpha phosphorylation.
-
Mojave toxin in venom of Crotalus helleri (Southern Pacific Rattlesnake): molecular and geographic characterization.
-
Molecular analysis of Drosophila melanogaster AdhnLA405 confirms reliability of DNA-sequencing methodology.
-
Molecular analysis of HLA-B35 alleles and their relationship to HLA-B15 alleles.
-
Molecular analysis of mutations in a patient with purine nucleoside phosphorylase deficiency.
-
Molecular analysis of spontaneous nephrotropic anti-laminin antibodies in an autoimmune MRL-lpr/lpr mouse.
-
Molecular analysis of the 60-kDa human Ro ribonucleoprotein.
-
Molecular analysis of the Cryptococcus neoformans ADE2 gene, a selectable marker for transformation and gene disruption.
-
Molecular analysis of the cDNA for human SPARC/osteonectin/BM-40: sequence, expression, and localization of the gene to chromosome 5q31-q33.
-
Molecular and biochemical characterization of two plant inositol polyphosphate 6-/3-/5-kinases.
-
Molecular and immunochemical analyses of RB1 and cyclin D1 in human ductal pancreatic carcinomas and cell lines.
-
Molecular and phenotypic characterization of a new mouse insertional mutation that causes a defect in the distal vertebrae of the spine.
-
Molecular and structural analysis of nuclear localizing anti-DNA lupus antibodies.
-
Molecular approaches to identify novel targets for future development of antifungal agents.
-
Molecular basis for the enterocyte tropism exhibited by Salmonella typhimurium type 1 fimbriae.
-
Molecular basis of adenosine deaminase deficiency.
-
Molecular basis of reduced or absent expression of decay-accelerating factor in Cromer blood group phenotypes.
-
Molecular biology as a tool for taxonomy.
-
Molecular biology of the vitamin D hormone.
-
Molecular characterization of CLPT1, a SEC4-like Rab/GTPase of the phytopathogenic fungus Colletotrichum lindemuthianum which is regulated by the carbon source.
-
Molecular characterization of MHC class II antigens (beta 1 domain) in the BB diabetes-prone and -resistant rat.
-
Molecular characterization of Rickettsia rickettsii infecting dogs and people in North Carolina.
-
Molecular characterization of TRP1, a gene coding for tryptophan synthetase in the basidiomycete Coprinus cinereus.
-
Molecular characterization of anti-DNA antibodies induced in normal mice by immunization with bacterial DNA. Differences from spontaneous anti-DNA in the content and location of VH CDR3 arginines.
-
Molecular cloning and analysis of functional envelope genes from human immunodeficiency virus type 1 sequence subtypes A through G. The WHO and NIAID Networks for HIV Isolation and Characterization.
-
Molecular cloning and characterization of Aspergillus nidulans cyclophilin B.
-
Molecular cloning and characterization of a distinct human phosphodiesterase gene family: PDE11A.
-
Molecular cloning and expression of cDNA encoding a peripheral-type benzodiazepine receptor.
-
Molecular cloning and expression of the cDNA for a novel alpha 1-adrenergic receptor subtype.
-
Molecular cloning and expression of the cDNA for the alpha 1A-adrenergic receptor. The gene for which is located on human chromosome 5.
-
Molecular cloning and expression of the cDNA for the hamster alpha 1-adrenergic receptor.
-
Molecular cloning and functional expression of a recombinant 72.5 kDa fragment of the 110 kDa regulatory subunit of smooth muscle protein phosphatase 1M.
-
Molecular cloning and nucleotide sequence of a cDNA clone coding for the cell attachment domain in human fibronectin.
-
Molecular cloning and nucleotide sequence of cDNA encoding human muscle glycogen debranching enzyme.
-
Molecular cloning and properties of a full-length putative thyroid hormone receptor coactivator.
-
Molecular cloning and restriction endonuclease mapping of the murine cytomegalovirus genome (Smith Strain).
-
Molecular cloning and sequence analysis of a cDNA coding for the mouse alpha-like embryonic globin chain x.
-
Molecular cloning and sequencing of DNA complementary to chicken liver fatty acid synthase mRNA.
-
Molecular cloning and sequencing of chicken liver fatty acid synthase cDNA.
-
Molecular cloning and sequencing of zeta-crystallin/quinone reductase cDNA from human liver.
-
Molecular cloning of KS, a novel rat gene expressed exclusively in the kidney.
-
Molecular cloning of a new human G protein. Evidence for two Gi alpha-like protein families.
-
Molecular cloning of a novel gene encoding a membrane-associated adaptor protein (LAX) in lymphocyte signaling.
-
Molecular cloning of acid alpha-glucosidase cDNA of Japanese quail (Coturnix coturnix japonica) and the lack of its mRNA in acid maltase deficient quails.
-
Molecular cloning of cDNA that encode MHC class I molecules from a New World primate (Saguinus oedipus). Natural selection acts at positions that may affect peptide presentation to T cells.
-
Molecular cloning of dimethyl sulfoxide reductase from Rhodobacter sphaeroides.
-
Molecular cloning of protein phosphatase inhibitor-1 and its expression in rat and rabbit tissues.
-
Molecular cloning of rainbow trout (Oncorhynchus mykiss) eggshell zona radiata protein complementary DNA: mRNA expression in 17beta-estradiol- and nonylphenol-treated fish.
-
Molecular cloning of rat glucose-dependent insulinotropic peptide (GIP).
-
Molecular cloning of rat liver sulfite oxidase. Expression of a eukaryotic Mo-pterin-containing enzyme in Escherichia coli.
-
Molecular cloning of the cDNA and promoter sequences for the mouse sodium-hydrogen exchanger regulatory factor.
-
Molecular cloning of the cDNA for androgen-dependent sperm-coating glycoproteins secreted by the rat epididymis.
-
Molecular cloning of the cDNA for ligatin.
-
Molecular cloning of the cDNA for two major androgen-dependent secretory proteins of 18.5 kilodaltons synthesized by the rat epididymis.
-
Molecular cloning of the first metazoan beta-1,3 glucanase from eggs of the sea urchin Strongylocentrotus purpuratus.
-
Molecular cloning of the gene sequences of a major apoprotein in avian very low density lipoproteins.
-
Molecular cloning of the structural gene for exopolygalacturonate lyase from Erwinia chrysanthemi EC16 and characterization of the enzyme product.
-
Molecular cloning sequence and distribution of rat calspermin, a high affinity calmodulin-binding protein.
-
Molecular cloning, characterization, and expression in Escherichia coli of full-length cDNAs of three human glutathione S-transferase Pi gene variants. Evidence for differential catalytic activity of the encoded proteins.
-
Molecular cloning, expression and functional characterization of rabbit anticoagulant vitamin-K-dependent protein S.
-
Molecular cloning, nucleotide sequence, and marker exchange mutagenesis of the exo-poly-alpha-D-galacturonosidase-encoding pehX gene of Erwinia chrysanthemi EC16.
-
Molecular defects underlying the Kell null phenotype.
-
Molecular ecology and natural history of simian foamy virus infection in wild-living chimpanzees.
-
Molecular evidence for dual pyrethroid-receptor sites on a mosquito sodium channel.
-
Molecular evolution of X-linked accessory gland proteins in Drosophila pseudoobscura.
-
Molecular evolution of a Drosophila homolog of human BRCA2.
-
Molecular evolutionary characterization of a V1R subfamily unique to strepsirrhine primates.
-
Molecular genetic analysis of two human sperm fibrous sheath proteins, AKAP4 and AKAP3, in men with dysplasia of the fibrous sheath.
-
Molecular hallmarks of endogenous chromatin complexes containing master regulators of hematopoiesis.
-
Molecular mapping of the Cromer blood group Cra and Tca epitopes of decay accelerating factor: toward the use of recombinant antigens in immunohematology.
-
Molecular mechanism by which the nucleoid occlusion factor, SlmA, keeps cytokinesis in check.
-
Molecular mechanism of fibronectin gene activation by cyclic stretch in vascular smooth muscle cells.
-
Molecular mechanism of tissue-specific regulation of mouse renin gene expression by cAMP. Identification of an inhibitory protein that binds nuclear transcriptional factor.
-
Molecular mycology: DNA probes and applications of PCR technology.
-
Molecular organization and alternative splicing in zipper, the gene that encodes the Drosophila non-muscle myosin II heavy chain.
-
Molecular phylogeny of naidid worms (Annelida: Clitellata) based on cytochrome oxidase I.
-
Molecular phylogeny of the Mycobacterium avium complex demonstrates clinically meaningful divisions.
-
Molecular phylogeny, biogeography and speciation of the mushroom species Pleurotus cystidiosus and allied taxa.
-
Molecular properties of anti-DNA induced in preautoimmune NZB/W mice by immunization with bacterial DNA.
-
Molecular recognition of ketamine by a subset of olfactory G protein-coupled receptors.
-
Molecular structure and flanking nucleotide sequences of the natural chicken ovomucoid gene.
-
Molecular structure of a protein-tyrosine/threonine kinase activating p42 mitogen-activated protein (MAP) kinase: MAP kinase kinase.
-
Molybdopterin synthase mutations in a mild case of molybdenum cofactor deficiency.
-
Monoclonal antibodies against EGFRvIII are tumor specific and react with breast and lung carcinomas and malignant gliomas.
-
Morphogenesis in Drosophila requires nonmuscle myosin heavy chain function.
-
Mosaic overgrowth with fibroadipose hyperplasia is caused by somatic activating mutations in PIK3CA.
-
Mosaicism for an FMR1 gene deletion in a fragile X female.
-
Motif composition, conservation and condition-specificity of single and alternative transcription start sites in the Drosophila genome.
-
Mouse Mesenchyme forkhead 2 (Mf2): expression, DNA binding and induction by sonic hedgehog during somitogenesis.
-
Mouse Small eye results from mutations in a paired-like homeobox-containing gene.
-
Mouse cytomegalovirus reactivation in severe combined immune deficient mice after implantation of latently infected salivary gland.
-
Mouse embryonic germ (EG) cell lines: transmission through the germline and differences in the methylation imprint of insulin-like growth factor 2 receptor (Igf2r) gene compared with embryonic stem (ES) cell lines.
-
Mouse microcytic anaemia caused by a defect in the gene encoding the globin enhancer-binding protein NF-E2.
-
Mouse model of OPRM1 (A118G) polymorphism has sex-specific effects on drug-mediated behavior.
-
Mouse small eye results from mutations in a paired-like homeobox-containing gene.
-
Mouse/human chimeric Me1-14 antibody: genomic cloning of the variable region genes, linkage to human constant region genes, expression, and characterization.
-
Msx1 and Pax3 cooperate to mediate FGF8 and WNT signals during Xenopus neural crest induction.
-
Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies.
-
Multilaboratory evaluation of screening methods for detection of high-level aminoglycoside resistance in enterococci. National Committee for Clinical Laboratory Standards Study Group on Enterococci.
-
Multiple alpha subunits of guanine nucleotide-binding proteins in Dictyostelium.
-
Multiple domains of MCIP1 contribute to inhibition of calcineurin activity.
-
Multiple forms of beta-amyloid peptide precursor RNAs in a single cell type.
-
Multiple interactions within the AKAP220 signaling complex contribute to protein phosphatase 1 regulation.
-
Multiple origins of hybrid strains of Cryptococcus neoformans with serotype AD.
-
Multiple phenotypic changes in mice after knockout of the B3gnt5 gene, encoding Lc3 synthase--a key enzyme in lacto-neolacto ganglioside synthesis.
-
Multiple potential regulatory elements in the 5' flanking region of the human alpha 1a-adrenergic receptor.
-
Multiple proteins interact with the nuclear inhibitory protein repressor element in the human interleukin-3 promoter.
-
Multiple red cell ferritin mRNAs, which code for an abundant protein in the embryonic cell type, analyzed by cDNA sequence and by primer extension of the 5'-untranslated regions.
-
Multiple structural elements define the specificity of recombinant human inhibitor-1 as a protein phosphatase-1 inhibitor.
-
Multiple transcription start sites and 5' alternate splicing of murine IL-3 receptor beta-chain transcripts.
-
Multiple, conserved cryptic recombination signals in VH gene segments: detection of cleavage products only in pro B cells.
-
Multivalent RNA aptamers that inhibit CTLA-4 and enhance tumor immunity.
-
Murine cytomegalovirus retinitis during retrovirus-induced immunodeficiency (MAIDS) in mice: interleukin-2 immunotherapy correlates with increased intraocular levels of perforin mRNA.
-
Murine forkhead/winged helix genes Foxc1 (Mf1) and Foxc2 (Mfh1) are required for the early organogenesis of the kidney and urinary tract.
-
Murine noroviruses comprising a single genogroup exhibit biological diversity despite limited sequence divergence.
-
MutS and MutL activate DNA helicase II in a mismatch-dependent manner.
-
Mutagenesis by exocyclic alkylamino purine adducts in Escherichia coli.
-
Mutagenic analysis of functional domains of the mos proto-oncogene and identification of the sites important for MAPK activation and DNA binding.
-
Mutagenic processing of ribonucleotides in DNA by yeast topoisomerase I.
-
Mutants of the Drosophila ncd microtubule motor protein cause centrosomal and spindle pole defects in mitosis.
-
Mutants of the EcoRI endonuclease with promiscuous substrate specificity implicate residues involved in substrate recognition.
-
Mutation analysis of the RET receptor tyrosine kinase in Hirschsprung disease.
-
Mutation analysis of the THRA1 gene in breast cancer: deletion/fusion of the gene to a novel sequence on 17q in the BT474 cell line.
-
Mutation analysis of the TSC2 gene in an African-American family.
-
Mutation and evolution of microsatellites in Drosophila melanogaster.
-
Mutation and expression analysis of the endoglin gene in hereditary hemorrhagic telangiectasia reveals null alleles.
-
Mutation detection with MutH, MutL, and MutS mismatch repair proteins.
-
Mutation exposed: a neutral explanation for extreme base composition of an endosymbiont genome.
-
Mutation in collagen II alpha 1 isoforms delineates Stickler and Wagner syndrome phenotypes.
-
Mutation in the mismatch repair gene Msh6 causes cancer susceptibility.
-
Mutation near the polyoma DNA replication origin permits productive infection of F9 embryonal carcinoma cells.
-
Mutation of Jak3 in a patient with SCID: essential role of Jak3 in lymphoid development.
-
Mutation of MSH3 in endometrial cancer and evidence for its functional role in heteroduplex repair.
-
Mutation of MYH9, encoding non-muscle myosin heavy chain A, in May-Hegglin anomaly.
-
Mutation of potassium permanganate- and hydrogen peroxide-treated plasmid pZ189 replicating in CV-1 monkey kidney cells.
-
Mutation of the p53 tumor-suppressor gene is not a feature of endometrial hyperplasias.
-
Mutation spectrum of 2-chloroethyl methanesulfonate in Drosophila melanogaster premeiotic germ cells.
-
Mutational Dissection of Telomeric DNA Binding Requirements of G4 Resolvase 1 Shows that G4-Structure and Certain 3'-Tail Sequences Are Sufficient for Tight and Complete Binding.
-
Mutational analysis of a type II topoisomerase cleavage site: distinct requirements for enzyme and inhibitors.
-
Mutational analysis of active site residues in the Staphylococcus aureus transpeptidase SrtA.
-
Mutational analysis of conserved N-linked glycosylation sites of human immunodeficiency virus type 1 gp41.
-
Mutational analysis of the autoinhibitory domain of calmodulin kinase II.
-
Mutational analysis of the leucine zipper-like motif of the human immunodeficiency virus type 1 envelope transmembrane glycoprotein.
-
Mutational analysis of the p21/WAF1/CIP1/SDI1 coding region in human tumor cell lines.
-
Mutational analysis of the trans-activation-responsive region of the human immunodeficiency virus type I long terminal repeat.
-
Mutational fingerprints of aging.
-
Mutational spectrum of the ZEB1 gene in corneal dystrophies supports a genotype-phenotype correlation.
-
Mutations Preventing Regulated Exon Skipping in MET Cause Osteofibrous Dysplasia.
-
Mutations causing hemophilia B: direct estimate of the underlying rates of spontaneous germ-line transitions, transversions, and deletions in a human gene.
-
Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination.
-
Mutations in SCO2 are associated with autosomal-dominant high-grade myopia.
-
Mutations in SLC19A2 cause thiamine-responsive megaloblastic anaemia associated with diabetes mellitus and deafness.
-
Mutations in a dominant Nef epitope of simian immunodeficiency virus diminish TCR:epitope peptide affinity but not epitope peptide:MHC class I binding.
-
Mutations in exon 3 of the glycogen debranching enzyme gene are associated with glycogen storage disease type III that is differentially expressed in liver and muscle.
-
Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas.
-
Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities.
-
Mutations in the MSH3 gene preferentially lead to deletions within tracts of simple repetitive DNA in Saccharomyces cerevisiae.
-
Mutations in the activin receptor-like kinase 1 gene in hereditary haemorrhagic telangiectasia type 2.
-
Mutations in the chemokine receptor gene CXCR4 are associated with WHIM syndrome, a combined immunodeficiency disease.
-
Mutations in the glucose-6-phosphatase gene are associated with glycogen storage disease types 1a and 1aSP but not 1b and 1c.
-
Mutations in the medium chain acyl-CoA dehydrogenase (MCAD) gene.
-
Mutations in the segment polarity genes wingless and porcupine impair secretion of the wingless protein.
-
Mutations of the BRAF gene in human cancer.
-
Mutations of the E-cadherin gene in human gynecologic cancers.
-
Mutations of the forkhead/winged-helix gene, FKHL7, in patients with Axenfeld-Rieger anomaly.
-
Mutations that affect Tn5 insertion into pBR322: importance of local DNA supercoiling.
-
Mutations that perturb cyclophilin A ligand binding pocket confer cyclosporin A resistance in Saccharomyces cerevisiae.
-
Myocyte nuclear factor, a novel winged-helix transcription factor under both developmental and neural regulation in striated myocytes.
-
Myosin light chain-2 luciferase transgenic mice reveal distinct regulatory programs for cardiac and skeletal muscle-specific expression of a single contractile protein gene.
-
Myristoylation of calcineurin B is not required for function or interaction with immunophilin-immunosuppressant complexes in the yeast Saccharomyces cerevisiae.
-
N-myc regulates parkin expression.
-
N-terminal and central regions of the human CD44 extracellular domain participate in cell surface hyaluronan binding.
-
N7-cyanoborane-2'-deoxyguanosine 5'-triphosphate is a good substrate for DNA polymerase.
-
NAD(P)H:quinone oxidoreductase expression and mitomycin C resistance developed by human colon cancer HCT 116 cells.
-
NADPH oxidase AtrbohD and AtrbohF genes function in ROS-dependent ABA signaling in Arabidopsis.
-
NF-kappa B and transcriptional control of renal epithelial-inducible nitric oxide synthase.
-
NF-kappaB cis-acting motifs of the human immunodeficiency virus (HIV) long terminal repeat regulate HIV transcription in human macrophages.
-
NF-kappaB factors are essential, but not the switch, for pathogen-related induction of the bovine beta-defensin 5-encoding gene in mammary epithelial cells.
-
NF-kappaB inhibition by an adenovirus expressed aptamer sensitizes TNFalpha-induced apoptosis.
-
NF1-related locus on chromosome 15.
-
NMDA and nitric oxide act through the cGMP signal transduction pathway to repress hypothalamic gonadotropin-releasing hormone gene expression.
-
NMR and XAS reveal an inner-sphere metal binding site in the P4 helix of the metallo-ribozyme ribonuclease P.
-
NPAS3 is a trachealess homolog critical for lung development and homeostasis.
-
NPR1 modulates cross-talk between salicylate- and jasmonate-dependent defense pathways through a novel function in the cytosol.
-
NPY and galanin in a hibernator: hypothalamic gene expression and effects on feeding.
-
Natural IgM is produced by CD5- plasma cells that occupy a distinct survival niche in bone marrow.
-
Natural genetic variants influencing type 1 diabetes in humans and in the NOD mouse.
-
Natural infection of a household pet red-capped mangabey (Cercocebus torquatus torquatus) with a new simian immunodeficiency virus.
-
Natural variation in HIV-1 protease, Gag p7 and p6, and protease cleavage sites within gag/pol polyproteins: amino acid substitutions in the absence of protease inhibitors in mothers and children infected by human immunodeficiency virus type 1.
-
Nature and distribution of large sequence polymorphisms in Saccharomyces cerevisiae.
-
Nature of the 3'-terminal sequences of the plus and minus strands of the S1 gene of reovirus serotypes 1, 2 and 3.
-
Near full-length clones and reference sequences for subtype C isolates of HIV type 1 from three different continents.
-
Needle-in-a-haystack detection and identification of base substitution mutations in human tissues.
-
Negative control elements and cAMP responsive sequences in the tissue-specific expression of mouse renin genes.
-
Neisseria gonorrhoeae FitA interacts with FitB to bind DNA through its ribbon-helix-helix motif.
-
Neurabin/protein phosphatase-1 complex regulates dendritic spine morphogenesis and maturation.
-
Neurabins recruit protein phosphatase-1 and inhibitor-2 to the actin cytoskeleton.
-
Neuronal expression of the Ccm2 gene in a new mouse model of cerebral cavernous malformations.
-
Neuronal pp60c-src contains a six-amino acid insertion relative to its non-neuronal counterpart.
-
Neutralization-sensitive R5-tropic simian-human immunodeficiency virus SHIV-2873Nip, which carries env isolated from an infant with a recent HIV clade C infection.
-
Neutralizing antibodies as a potential secondary protective mechanism during chronic SHIV infection in CD8+ T-cell-depleted macaques.
-
New member of the trefoil factor family of proteins is an alpha-macroglobulin protease inhibitor.
-
New simian immunodeficiency virus infecting De Brazza's monkeys (Cercopithecus neglectus): evidence for a cercopithecus monkey virus clade.
-
New species of Xerocomus (Boletales) from the Guiana Shield, with notes on their mycorrhizal status and fruiting occurrence
-
New techniques for DNA sequence classification.
-
Next-generation sequencing of apoptotic DNA breakpoints reveals association with actively transcribed genes and gene translocations.
-
Next‐generation polyploid phylogenetics: Rapid resolution of hybrid polyploid complexes using PacBio single‐molecule sequencing
-
Nitric oxide-associated regulation of hepatocyte glutathione synthesis is a guanylyl cyclase-independent event.
-
Nodal is a novel TGF-beta-like gene expressed in the mouse node during gastrulation.
-
Nomenclature: vertebrate mediators of TGFbeta family signals.
-
Non-function of a Moloney murine leukaemia virus regulatory sequence in F9 embryonal carcinoma cells.
-
Noncanonical secondary structure stabilizes mitochondrial tRNA(Ser(UCN)) by reducing the entropic cost of tertiary folding.
-
Noncoding transcription controls downstream promoters to regulate T-cell receptor alpha recombination.
-
Nonconsensus Protein Binding to Repetitive DNA Sequence Elements Significantly Affects Eukaryotic Genomes.
-
Nonhomogeneous model of sequence evolution indicates independent origins of primary endosymbionts within the enterobacteriales (gamma-Proteobacteria).
-
Nonmuscle myosin II generates forces that transmit tension and drive contraction in multiple tissues during dorsal closure.
-
Nonmuscle myosin II is required for cell proliferation, cell sheet adhesion and wing hair morphology during wing morphogenesis.
-
Nonrandom distribution of gp120 N-linked glycosylation sites important for infectivity of human immunodeficiency virus type 1.
-
Nonrandom distribution of interhomolog recombination events induced by breakage of a dicentric chromosome in Saccharomyces cerevisiae.
-
Normal luminal bacteria, especially Bacteroides species, mediate chronic colitis, gastritis, and arthritis in HLA-B27/human beta2 microglobulin transgenic rats.
-
Normalization of the peripheral blood T cell receptor V beta repertoire after cultured postnatal human thymic transplantation in DiGeorge syndrome.
-
North Carolina macular dystrophy is assigned to chromosome 6.
-
Novel DNA sequence variations of cytochrome P450 genes in the Han Chinese population.
-
Novel bacterial P-type ATPases with histidine-rich heavy-metal-associated sequences.
-
Novel compound heterozygous mutations in MYO7A in a Chinese family with Usher syndrome type 1.
-
Novel estrogen response elements identified by genetic selection in yeast are differentially responsive to estrogens and antiestrogens in mammalian cells.
-
Novel gene functions required for melanization of the human pathogen Cryptococcus neoformans.
-
Novel repression of Kcc2 transcription by REST-RE-1 controls developmental switch in neuronal chloride.
-
Novel splicing, missense, and deletion mutations in seven adenosine deaminase-deficient patients with late/delayed onset of combined immunodeficiency disease. Contribution of genotype to phenotype.
-
Novel susceptibility gene for nonfamilial hypokalemic periodic paralysis.
-
Novel tyrosine kinase identified by phosphotyrosine antibody screening of cDNA libraries.
-
Nuclear DNA from primate dug
-
Nuclear expression of the 50- and 65-kD Rel-related subunits of nuclear factor-kappa B is differentially regulated in human monocytic cells.
-
Nuclear localization of NPR1 is required for activation of PR gene expression.
-
Nuclear protein CBP is a coactivator for the transcription factor CREB.
-
Nuclear responses to depletion of mitochondrial DNA in human cells.
-
Nuclear ribosomal DNA sequence variation and evolution of spotted marsh-orchids (Dactylorhiza maculata group)
-
Nucleic acid aptamers in therapeutic anticoagulation. Technology, development and clinical application.
-
Nucleic acid sequence and oncogenic properties of the HZ2 feline sarcoma virus v-abl insert.
-
Nucleotide sequence and expression of the human skeletal alpha-actin gene: evolution of functional regulatory domains.
-
Nucleotide sequence and high-level expression of the major Escherichia coli phosphofructokinase.
-
Nucleotide sequence and host La protein interactions of rabies virus leader RNA.
-
Nucleotide sequence homology at the 3' termini of RNA from vesicular stomatitis virus and its defective interfering particles.
-
Nucleotide sequence of a cDNA for a member of the human 90-kDa heat-shock protein family.
-
Nucleotide sequence of a gene cluster involved in entry of E colicins and single-stranded DNA of infecting filamentous bacteriophages into Escherichia coli.
-
Nucleotide sequence of the LYS2 gene of Saccharomyces cerevisiae: homology to Bacillus brevis tyrocidine synthetase 1.
-
Nucleotide sequence preference at rat liver and wheat germ type 1 DNA topoisomerase breakage sites in duplex SV40 DNA.
-
Nucleotide sequence, expression, and chromosomal mapping of Mrp and mapping of five related sequences.
-
Nucleotide sequences of the RNA subunit of RNase P from several mammals.
-
Nucleotide variation at the myrosinase-encoding locus, TGG1, and quantitative myrosinase enzyme activity variation in Arabidopsis thaliana.
-
Numerous group I introns with variable distributions in the ribosomal DNA of a lichen fungus.
-
Odorant receptors and desensitization proteins colocalize in mammalian sperm.
-
Oligodendroglial and pan-neural crest expression of Cre recombinase directed by Sox10 enhancer.
-
Oligodontia is caused by mutation in LTBP3, the gene encoding latent TGF-beta binding protein 3.
-
Oligonucleotide transformation of yeast reveals mismatch repair complexes to be differentially active on DNA replication strands.
-
On the origins, structures and functions of restriction-modification enzymes.
-
On the physiological importance of endoproteolysis of CAAX proteins: heart-specific RCE1 knockout mice develop a lethal cardiomyopathy.
-
On the role of human herpesvirus 6 in viral latency in nervous tissue and in cerebral lymphoma.
-
Oncogenes and anti-oncogenes in human central nervous system tumors.
-
Oncogenic Ras-induced secretion of IL6 is required for tumorigenesis.
-
Oncogenic activation of c-ABL by mutation within its last exon.
-
Oncogenic base substitution mutations in circulating leukocytes of normal individuals.
-
Oncogenic human papillomavirus type 16 is associated with squamous cell cancer of the male urethra.
-
Oncogenic human papillomaviruses are rarely associated with squamous cell carcinoma of the bladder: evaluation by differential polymerase chain reaction.
-
Oncogenic point mutations in the human retinoblastoma gene: their application to genetic counseling.
-
One binding site determines sequence specificity of Tetrahymena pre-rRNA self-splicing, trans-splicing, and RNA enzyme activity.
-
Ontogenesis of prolactin receptor gene expression in the rat olfactory system: potential roles for lactogenic hormones in olfactory development.
-
Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity.
-
Optimal self-cleavage activity of the hepatitis delta virus RNA is dependent on a homopurine base pair in the ribozyme core.
-
Optimizing the substrate specificity of a group I intron ribozyme.
-
Organization and analysis of the complete rat calmodulin-dependent protein kinase IV gene.
-
Organization and evolutionary trajectory of the mating type (MAT) locus in dermatophyte and dimorphic fungal pathogens.
-
Organization of ribosomal DNA in the basidiomycete Thanatephorus praticola.
-
Organization of the MASP2 locus and its expression profile in mouse and rat.
-
Organization of the human zeta-crystallin/quinone reductase gene (CRYZ).
-
Origin of fetal troponin T: developmentally regulated splicing of a new exon in the fast troponin T gene.
-
Origins and prevalence of the American Founder Mutation of MSH2.
-
Osteopontin is up-regulated in chronic hepatitis C and is associated with cellular permissiveness for hepatitis C virus replication.
-
Ovarian cancer progression is controlled by phenotypic changes in dendritic cells.
-
Ovarian cycling and reproductive state shape the vaginal microbiota in wild baboons.
-
Overexpression and mutation of p53 in endometrial carcinoma.
-
Overexpression of RRE-derived sequences inhibits HIV-1 replication in CEM cells.
-
Overexpression of TAR sequences renders cells resistant to human immunodeficiency virus replication.
-
Overexpression of leptin receptors in pancreatic islets of Zucker diabetic fatty rats restores GLUT-2, glucokinase, and glucose-stimulated insulin secretion.
-
Overexpression of protein targeting to glycogen (PTG) in rat hepatocytes causes profound activation of glycogen synthesis independent of normal hormone- and substrate-mediated regulatory mechanisms.
-
Overlapping transcription units in the transient receptor potential locus of Drosophila melanogaster.
-
Overproduction and purification of glutaryl 7-amino cephalosporanic acid acylase.
-
Ovomucoid intervening sequences specify functional domains and generate protein polymorphism.
-
Oxidative DNA base damage in MCF-10A breast epithelial cells at clinically achievable concentrations of doxorubicin.
-
Oxidized low density lipoprotein suppresses activation of NF kappa B in macrophages via a pertussis toxin-sensitive signaling mechanism.
-
P1 partition complex assembly involves several modes of protein-DNA recognition.
-
PCGEM1, a prostate-specific gene, is overexpressed in prostate cancer.
-
PCR identification of Mycobacterium bovis BCG.
-
PIG-A, DAF and proto-oncogene expression in paroxysmal nocturnal haemoglobinuria-associated acute myelogenous leukaemia blasts.
-
PIL5, a phytochrome-interacting bHLH protein, regulates gibberellin responsiveness by binding directly to the GAI and RGA promoters in Arabidopsis seeds
-
PLP/DM20 ratio is regulated by hnRNPH and F and a novel G-rich enhancer in oligodendrocytes.
-
POWRS: position-sensitive motif discovery.
-
PP1 control of M phase entry exerted through 14-3-3-regulated Cdc25 dephosphorylation.
-
PSGR, a novel prostate-specific gene with homology to a G protein-coupled receptor, is overexpressed in prostate cancer.
-
Palindromic sequences in heteroduplex DNA inhibit mismatch repair in yeast.
-
Pancreatic adenocarcinoma cell line, MDAPanc-28, with features of both acinar and ductal cells.
-
Pancreatic islets and insulinoma cells express a novel isoform of group VIA phospholipase A2 (iPLA2 beta) that participates in glucose-stimulated insulin secretion and is not produced by alternate splicing of the iPLA2 beta transcript.
-
Parallel analysis of ribonucleotide-dependent deletions produced by yeast Top1 in vitro and in vivo.
-
Parallel evolution of drug resistance in HIV: failure of nonsynonymous/synonymous substitution rate ratio to detect selection.
-
Parent-specific expression of a human keratin 18/beta-galactosidase fusion gene in transgenic mice.
-
Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity.
-
Partial correction of endogenous DeltaF508 CFTR in human cystic fibrosis airway epithelia by spliceosome-mediated RNA trans-splicing.
-
Partial inactivation of the RB product in a family with incomplete penetrance of familial retinoblastoma and benign retinal tumors.
-
Partial shotgun sequencing of the Boechera stricta genome reveals extensive microsynteny and promoter conservation with Arabidopsis.
-
Passively transferred antibodies directed against conserved regions of SIV envelope protect macaques from SIV infection.
-
Pathway for lipid A biosynthesis in Arabidopsis thaliana resembling that of Escherichia coli.
-
Patterns of HIV-1 mRNA expression in transgenic mice are tissue-dependent.
-
Patterns of nucleotide diversity in two species of Mimulus are affected by mating system and asymmetric introgression.
-
Patterns of nucleotide variation and reproductive isolation between a Mimulus allotetraploid and its progenitor species.
-
Patterns of viral replication correlate with outcome in simian immunodeficiency virus (SIV)-infected macaques: effect of prior immunization with a trivalent SIV vaccine in modified vaccinia virus Ankara.
-
Pcp1p, an Spc110p-related calmodulin target at the centrosome of the fission yeast Schizosaccharomyces pombe.
-
Pde1 phosphodiesterase modulates cyclic AMP levels through a protein kinase A-mediated negative feedback loop in Cryptococcus neoformans.
-
Peripheral blood chimerism in renal allograft recipients transfused with donor bone marrow.
-
Phage T3 DNA contains an exact copy of the 23 base-pair phage T7 RNA polymerase promoter sequence.
-
Phage Trojan horses: a conditional expression system for lethal genes.
-
Pharmacokinetics of antisense oligodeoxyribonucleotides (cyclin B1 and CDC 2 kinase) in the vessel wall in vivo: enhanced therapeutic utility for restenosis by HVJ-liposome delivery.
-
Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells.
-
Pharmacologic manipulation of ob expression in a dietary model of obesity.
-
Phenotypic and functional differences between human saphenous vein (HSVEC) and umbilical vein (HUVEC) endothelial cells.
-
Phenotypic properties of transmitted founder HIV-1.
-
Pheromones stimulate mating and differentiation via paracrine and autocrine signaling in Cryptococcus neoformans.
-
Phosphoregulation provides specificity to biomolecular condensates in the cell cycle and cell polarity.
-
Phosphorylation and activation of Ca(2+)-calmodulin-dependent protein kinase IV by Ca(2+)-calmodulin-dependent protein kinase Ia kinase. Phosphorylation of threonine 196 is essential for activation.
-
Phosphorylation and desensitization of the human beta 1-adrenergic receptor. Involvement of G protein-coupled receptor kinases and cAMP-dependent protein kinase.
-
Phosphorylation of the platelet-derived growth factor receptor-beta and epidermal growth factor receptor by G protein-coupled receptor kinase-2. Mechanisms for selectivity of desensitization.
-
Phosphorylation of the type 1A angiotensin II receptor by G protein-coupled receptor kinases and protein kinase C.
-
Phosphorylation of tristetraprolin, a potential zinc finger transcription factor, by mitogen stimulation in intact cells and by mitogen-activated protein kinase in vitro.
-
Phycomyces MADB interacts with MADA to form the primary photoreceptor complex for fungal phototropism.
-
Phylogenetic affiliations of members of the heterogeneous lichen-forming fungi of the genus Lecidea sensu Zahlbruckner (Lecanoromycetes, Ascomycota).
-
Phylogenetic analyses of morphological evolution in the gametophyte and sporophyte generations of the moss order Hookeriales (Bryopsida).
-
Phylogenetic evidence for the transfer of Pseudomonas cocovenenans (van Damme et al. 1960) to the genus Burkholderia as Burkholderia cocovenenans (van Damme et al. 1960) comb. nov.
-
Phylogenetic evidence of a rapid radiation of pleurocarpous mosses (Bryophyta).
-
Phylogenetic footprint analysis of IGF2 in extant mammals.
-
Phylogenetic relationships of agaric fungi based on nuclear large subunit ribosomal DNA sequences.
-
Phylogenetic study of Catapyrenium s. str. (Verrucariaceae, lichen-forming Ascomycota) and related genus Placidiopsis.
-
Phylogenetic utility of indels within ribosomal DNA and beta-tubulin sequences from fungi in the Rhizoctonia solani species complex.
-
Phylogenomics reveals convergent evolution of red-violet coloration in land plants and the origins of the anthocyanin biosynthetic pathway.
-
Phylogeny and biogeography of East Asian evergreen oaks (Quercus section Cyclobalanopsis; Fagaceae): Insights into the Cenozoic history of evergreen broad-leaved forests in subtropical Asia.
-
Phylogeny of extant and extinct Juglandaceae inferred from the integration of molecular and morphological data sets
-
Phylogeny of lichen- and non-lichen-forming omphalinoid mushrooms and the utility of testing for combinability among multiple data sets.
-
Physical and cDNA mapping in the DBH region of human chromosome 9q34.
-
Physical and chemical characterization of purified ovalbumin messenger RNA.
-
Physiologically regulated alternative splicing patterns of fast troponin T RNA are conserved in mammals.
-
Phytochrome diversity in green plants and the origin of canonical plant phytochromes
-
Phytochrome regulation and differential expression of gibberellin 3b-hydroxylase genes in germinating Arabidopsis seeds
-
Picornavirus genome replication. Identification of the surface of the poliovirus (PV) 3C dimer that interacts with PV 3Dpol during VPg uridylylation and construction of a structural model for the PV 3C2-3Dpol complex.
-
Plasmid protein TubR uses a distinct mode of HTH-DNA binding and recruits the prokaryotic tubulin homolog TubZ to effect DNA partition.
-
Plasmids for recombination-based screening.
-
Plasminogen activator inhibitor-1 (PAI-1) modifies the formation of aggressive fibromatosis (desmoid tumor).
-
Plasmonics nanoprobes: detection of single-nucleotide polymorphisms in the breast cancer BRCA1 gene.
-
Plasticity in the adult human oligodendrocyte lineage.
-
Plasticity of lipid-protein interactions in the function and topogenesis of the membrane protein lactose permease from Escherichia coli.
-
Platelet-derived growth factor in fibrous musculoskeletal disorders: a study of pathologic tissue sections and in vitro primary cell cultures.
-
Poliovirus replicase stimulation by terminal uridylyl transferase.
-
Polycistronic vesicular stomatitis virus RNA transcripts.
-
Polycystic kidney disease as a result of loss of the tuberous sclerosis 2 tumor suppressor gene during development.
-
Polymerase chain reaction detection of the BCR-ABL fusion transcript after allogeneic marrow transplantation for chronic myeloid leukemia: results and implications in 346 patients.
-
Polymerase chain reaction fingerprinting in fungi using single primers specific to minisatellites and simple repetitive DNA sequences: strain variation in Cryptococcus neoformans.
-
Polymorphic hCHK2/hCds1 codon 84 allele and risk of squamous cell carcinoma of the head and neck--a case-control analysis.
-
Polymorphic markers of the glycogen debranching enzyme gene allowing linkage analysis in families with glycogen storage disease type III.
-
Polymorphism at the ribosomal DNA spacers and its relation to breeding structure of the widespread mushroom Schizophyllum commune.
-
Polymorphism of adhesion molecule CD31 and its role in acute graft-versus-host disease.
-
Polymorphisms and evolutionary history of retrotransposon insertions in rice promoters.
-
Polymorphisms in genes encoding drug metabolizing enzymes and their influence on the outcome of children with neuroblastoma.
-
Polymorphisms of DNA repair gene XRCC1 in squamous cell carcinoma of the head and neck.
-
Polymorphisms of methionine synthase and methionine synthase reductase and risk of lung cancer: a case-control analysis.
-
Polymorphisms of the DNA repair gene MGMT and risk and progression of head and neck cancer.
-
Pooled deep sequencing of Plasmodium falciparum isolates: an efficient and scalable tool to quantify prevailing malaria drug-resistance genotypes.
-
Population genetic and phylogenetic evidence for positive selection on regulatory mutations at the factor VII locus in humans.
-
Population genetics of tandem trypsin inhibitor genes in Arabidopsis species with contrasting ecology and life history.
-
Porcine CD80: cloning, characterization, and evidence for its role in direct human T-cell activation.
-
Porcine granulosa cells do not express transforming growth factor-beta 2 (TGF-beta 2) messenger ribonucleic acid: molecular basis for their inability to produce TGF-beta activity comparable to that of rat granulosa cells.
-
Posaconazole exhibits in vitro and in vivo synergistic antifungal activity with caspofungin or FK506 against Candida albicans.
-
Positional cloning of a temperature-sensitive mutant emmental reveals a role for sly1 during cell proliferation in zebrafish fin regeneration.
-
Positive and negative elements regulate human interleukin 3 expression.
-
Positive selection on MMP3 regulation has shaped heart disease risk.
-
Post-transcription cleavage generates the 3' end of F17R transcripts in vaccinia virus.
-
Post-transcriptional regulation of myotube elongation and myogenesis by Hoi Polloi.
-
Postreceptor signal transduction by cyclic adenosine monophosphate and the Ca2+-calmodulin complex.
-
Posttranscriptional regulation of protein expression in human epithelial carcinoma cells by adenine-uridine-rich elements in the 3'-untranslated region of tumor necrosis factor-alpha messenger RNA.
-
Potent inhibition of human immunodeficiency virus type 1 (HIV-1) replication by inducible expression of HIV-1 PR multimers.
-
Potential mechanisms for increased HIV-1 transmission across the endocervical epithelium during C. trachomatis infection.
-
Potential role of WAF1/Cip1/p21 as a mediator of TGF-beta cytoinhibitory effect.
-
Potential sources of the 1995 Venezuelan equine encephalitis subtype IC epidemic.
-
Poxvirus genomes encode a secreted, soluble protein that preferentially inhibits beta chemokine activity yet lacks sequence homology to known chemokine receptors.
-
Precise arrangement of factor-binding sites is required for murine CD4 promoter function.
-
Precise localization of the FHIT gene to the common fragile site at 3p14.2 (FRA3B) and characterization of homozygous deletions within FRA3B that affect FHIT transcription in tumor cell lines.
-
Predicted group II intron lineages E and F comprise catalytically active ribozymes.
-
Predicting the pathogenicity of RPE65 mutations.
-
Predominance of beta-catenin mutations and beta-catenin dysregulation in sporadic aggressive fibromatosis (desmoid tumor).
-
Pregnancy without progesterone in horses defines a second endogenous biopotent progesterone receptor agonist, 5α-dihydroprogesterone.
-
Preliminary study using species-specific oligonucleotide probe for rRNA of Bilophila wadsworthia.
-
Preliminary x-ray diffraction studies of EcoRI restriction endonuclease-DNA complex.
-
Preparation and screening of an arrayed human genomic library generated with the P1 cloning system.
-
Preparation, resonance assignment, and preliminary dynamics characterization of residue specific 13C/15N-labeled elongated DNA for the study of sequence-directed dynamics by NMR.
-
Presence of large deletions in kindreds with autism.
-
Presenilin-dependent gamma-secretase-like intramembrane cleavage of ErbB4.
-
Pressure-mediated oligonucleotide transfection of rat and human cardiovascular tissues.
-
Prevalence of deleterious ATM germline mutations in gastric cancer patients.
-
Prevalence of human papillomavirus types 16 and 18 in squamous-cell carcinoma of the penis: a retrospective analysis of primary and metastatic lesions by differential polymerase chain reaction.
-
Prevention of graft-versus-host disease by peptides binding to class II major histocompatibility complex molecules.
-
Primary sequence of ovomucoid messenger RNA as determined from cloned complementary DNA.
-
Primary structure and domain organization of human alpha and beta adducin.
-
Primer3 on the WWW for general users and for biologist programmers.
-
Priming with plasmid DNAs expressing interleukin-12 and simian immunodeficiency virus gag enhances the immunogenicity and efficacy of an experimental AIDS vaccine based on recombinant vesicular stomatitis virus.
-
Principles and applications of a Tat-based assay for analyzing specific RNA-protein interactions in mammalian cells.
-
Probe directed at a segment of Rickettsia rickettsii rRNA amplified with polymerase chain reaction.
-
Probing sequence-specific DNA flexibility in a-tracts and pyrimidine-purine steps by nuclear magnetic resonance (13)C relaxation and molecular dynamics simulations.
-
Probing the architecture of the B. subtilis RNase P holoenzyme active site by cross-linking and affinity cleavage.
-
Probing the interplay between the two steps of group I intron splicing: competition of exogenous guanosine with omega G.
-
Processing of nuclear heterogeneous RNA: recent developments.
-
Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations.
-
Production and role of cytokines in the CNS of mice with acute viral encephalomyelitis.
-
Production of highly potent recombinant siRNAs in Escherichia coli.
-
Profiling microRNA expression in hepatocellular carcinoma reveals microRNA-224 up-regulation and apoptosis inhibitor-5 as a microRNA-224-specific target.
-
Progesterone-induced immunosuppression.
-
Progression of basal cell carcinoma through loss of chromosome 9q and inactivation of a single p53 allele.
-
Progressive island colonization and ancient origin of Hawaiian Metrosideros (Myrtaceae).
-
Prolactin induction of insulin gene transcription: roles of glucose and signal transducer and activator of transcription 5.
-
Prolactin receptor gene expression in the fetal rat.
-
Proliferative potential and resistance to immune checkpoint blockade in lung cancer patients.
-
Prolonged clinical latency and survival of macaques given a whole inactivated simian immunodeficiency virus vaccine.
-
Promoter analysis of Zfp-36, the mitogen-inducible gene encoding the zinc finger protein tristetraprolin.
-
Promoter hypermethylation profile of kidney cancer.
-
Proper function of the Drosophila trp gene product during pupal development is important for normal visual transduction in the adult.
-
Properties and regulation of the cell cycle-specific NIMA protein kinase of Aspergillus nidulans.
-
Prospective estimation of recombination signal efficiency and identification of functional cryptic signals in the genome by statistical modeling.
-
Proteasomal interaction as a critical activity modulator of the human constitutive androstane receptor.
-
Protection against daunorubicin cytotoxicity by expression of a cloned human carbonyl reductase cDNA in K562 leukemia cells.
-
Protection against lipoapoptosis of beta cells through leptin-dependent maintenance of Bcl-2 expression.
-
Protein isoforms encoded by the pX region of human T-cell leukemia/lymphotropic virus type I.
-
Protein kinase activity and identification of a toxic effector domain of the target of rapamycin TOR proteins in yeast.
-
Protein kinase activity of Tel1p and Mec1p, two Saccharomyces cerevisiae proteins related to the human ATM protein kinase.
-
Protein purification by fusion with an environmentally responsive elastin-like polypeptide: effect of polypeptide length on the purification of thioredoxin.
-
Protein roadblocks and helix discontinuities are barriers to the initiation of mismatch repair.
-
Protein-DNA binding in the absence of specific base-pair recognition.
-
Protein-interaction modules that organize nuclear function: FF domains of CA150 bind the phosphoCTD of RNA polymerase II.
-
Proton nuclear magnetic resonance assignments and structural characterization of an intramolecular DNA triplex.
-
Pseudo-von Willebrand disease: a mutation in the platelet glycoprotein Ib alpha gene associated with a hyperactive surface receptor.
-
Pseudomonas syringae pv. syringae harpinPss: a protein that is secreted via the Hrp pathway and elicits the hypersensitive response in plants.
-
Purification and characterization of zeta-crystallin/quinone reductase from guinea pig liver.
-
Purification and properties of EcoRI endonuclease.
-
Purification of recombinant proteins by fusion with thermally-responsive polypeptides.
-
Purification of the human NF-E2 complex: cDNA cloning of the hematopoietic cell-specific subunit and evidence for an associated partner.
-
Purification, cloning, and expression of a peripheral-type benzodiazepine receptor.
-
Purified MotA protein binds the -30 region of a bacteriophage T4 middle-mode promoter and activates transcription in vitro.
-
Putative human blue-light photoreceptors hCRY1 and hCRY2 are flavoproteins.
-
Quadruplex DNA formation in a region of the tRNA gene supF associated with hydrogen peroxide mediated mutations.
-
Quality of DNA extracted from mouthwashes.
-
Quantification of homoplasy for nucleotide transitions and transversions and a reexamination of assumptions in weighted phylogenetic analysis.
-
Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cells.
-
Quantitative modeling of transcription factor binding specificities using DNA shape.
-
Quorum-sensing regulation of a copper toxicity system in Pseudomonas aeruginosa.
-
RGS2-deficient mice exhibit decreased intraocular pressure and increased retinal ganglion cell survival.
-
RK2, a glial-specific homeodomain protein required for embryonic nerve cord condensation and viability in Drosophila.
-
RNA aptamer to thrombin binds anion-binding exosite-2 and alters protease inhibition by heparin-binding serpins.
-
RNA aptamers as reversible antagonists of coagulation factor IXa.
-
RNA editing generates tissue-specific sodium channels with distinct gating properties.
-
RNA polymerase-associated interactions near template promoter sequences of defective interfering particles of vesicular stomatitis virus.
-
RNA replication from the simian virus 5 antigenomic promoter requires three sequence-dependent elements separated by sequence-independent spacer regions.
-
RNA sequence and transcriptional properties of the 3' end of the Newcastle disease virus genome.
-
RNA subunit of mitochondrial RNA-processing enzyme is induced by contractile activity in striated muscle.
-
RNA surfaces as functional mimetics of proteins.
-
RNA-sequence-mediated gene regulation in HIV-1.
-
RNAi is a critical determinant of centromere evolution in closely related fungi.
-
RNase 1 genes from the family Sciuridae define a novel rodent ribonuclease cluster.
-
RNase H activation by stereoregular boranophosphate oligonucleotide.
-
RORgamma t, a novel isoform of an orphan receptor, negatively regulates Fas ligand expression and IL-2 production in T cells.
-
RU486 exerts antiestrogenic activities through a novel progesterone receptor A form-mediated mechanism.
-
RUNX1 maintains the identity of the fetal ovary through an interplay with FOXL2.
-
RalA regulates vascular endothelial growth factor-C (VEGF-C) synthesis in prostate cancer cells during androgen ablation.
-
Randomization and selection of RNA to identify targets for RRM RNA-binding proteins and antibodies.
-
Rapamycin antagonizes cyclosporin A- and tacrolimus (FK506)-mediated augmentation of linker for activation of T cell expression in T cells.
-
Rapamycin antifungal action is mediated via conserved complexes with FKBP12 and TOR kinase homologs in Cryptococcus neoformans.
-
Rapid 16S ribosomal DNA sequencing from a single colony without DNA extraction or purification.
-
Rapid DNA sequencing of more than 1000 bases per run by capillary electrophoresis using replaceable linear polyacrylamide solutions.
-
Rapid and transient localization of the leader RNA of vesicular stomatitis virus in the nuclei of infected cells.
-
Rapid chiral assembly of rigid DNA building blocks for molecular nanofabrication.
-
Rapid genetic identification and mapping of enzymatically amplified ribosomal DNA from several Cryptococcus species.
-
Rapid global expansion of the fungal disease chytridiomycosis into declining and healthy amphibian populations.
-
Rapid identification of Candida species by DNA fingerprinting with PCR.
-
Rapid shotgun cloning utilizing the two base recognition endonuclease CviJI.
-
Rapid, comprehensive analysis of human cytokine mRNA and its application to the study of acute renal allograft rejection.
-
Rapidly regulating platelet activity in vivo with an antidote controlled platelet inhibitor.
-
Rat amylin: cloning and tissue-specific expression in pancreatic islets.
-
Rat pancreatic kallikrein mRNA: nucleotide sequence and amino acid sequence of the encoded preproenzyme.
-
Re-annotation of the woodland strawberry (Fragaria vesca) genome.
-
Reaper is regulated by IAP-mediated ubiquitination.
-
Reaper-induced dissociation of a Scythe-sequestered cytochrome c-releasing activity.
-
Receptor class desensitization of leukocyte chemoattractant receptors.
-
Receptors for prostaglandin E(2) that regulate cellular immune responses in the mouse.
-
Receptors that induce erythroid differentiation of Ba/F3 cells: structural requirements and effect on STAT5 binding.
-
Reciprocal uniparental disomy in yeast.
-
Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha.
-
Recognition of U1 and U2 small nuclear RNAs can be altered by a 5-amino-acid segment in the U2 small nuclear ribonucleoprotein particle (snRNP) B" protein and through interactions with U2 snRNP-A' protein.
-
Recognition of single-stranded DNA by the bacteriophage T4-induced type II topoisomerase.
-
Recombinant human interleukin 1 alpha: purification and biological characterization.
-
Recombinant immunotoxin containing a disulfide-stabilized Fv directed at erbB2 that does not require proteolytic activation.
-
Recombinant single-chain variable fragment antibodies against extracellular epitopes of human multidrug resistance protein MRP3 for targeting malignant gliomas.
-
Recombination and gene conversion in a 170-kb genomic region of Arabidopsis thaliana.
-
Recombination between palindromes P5 and P1 on the human Y chromosome causes massive deletions and spermatogenic failure.
-
Recombination modulates how selection affects linked sites in Drosophila.
-
Recombination of 4p16 DNA markers in an unusual family with Huntington disease.
-
Recombination of plasmids into the Saccharomyces cerevisiae chromosome is reduced by small amounts of sequence heterogeneity.
-
Recombination, statistical power, and genetic studies of sexual isolation in Drosophila.
-
Recombination-dependent DNA replication stimulated by double-strand breaks in bacteriophage T4.
-
Recombining without Hotspots: A Comprehensive Evolutionary Portrait of Recombination in Two Closely Related Species of Drosophila.
-
Reconfigurable core-satellite nanoassemblies as molecularly-driven plasmonic switches
-
Recovery of a human natural antibody against the noncollagenous-1 domain of type IV collagen using humanized models.
-
Recruitment of a protein complex containing Tat and cyclin T1 to TAR governs the species specificity of HIV-1 Tat.
-
Recurrent TERT promoter mutations identified in a large-scale study of multiple tumour types are associated with increased TERT expression and telomerase activation.
-
Recurrent mutations in topoisomerase IIα cause a previously undescribed mutator phenotype in human cancers.
-
Recurrent polyploid origins and chloroplast phylogeography in the Arabis holboellii complex (Brassicaceae).
-
Reduced expression of brain-enriched microRNAs in glioblastomas permits targeted regulation of a cell death gene.
-
Reduced levels of DNA polymerase delta induce chromosome fragile site instability in yeast.
-
Reduced selective constraint in endosymbionts: elevation in radical amino acid replacements occurs genome-wide.
-
Reduced thymic output, increased spontaneous apoptosis and oligoclonal B cells in polyethylene glycol-adenosine deaminase-treated patients.
-
Refined localization of the cerebral cavernous malformation gene (CCM1) to a 4-cM interval of chromosome 7q contained in a well-defined YAC contig.
-
Refined mapping and YAC contig construction of the X-linked cleft palate and ankyloglossia locus (CPX) including the proximal X-Y homology breakpoint within Xq21.3.
-
Regenerative changes in C/EBP alpha and C/EBP beta expression modulate binding to the C/EBP site in the c-fos promoter.
-
Regional rearrangements in chromosome 15q21 cause formation of cryptic promoters for the CYP19 (aromatase) gene.
-
Regression of human kidney cancer following allogeneic stem cell transplantation is associated with recognition of an HERV-E antigen by T cells.
-
Regulated expression of p18, a major phosphoprotein of leukemic cells.
-
Regulation and function of the calcium/calmodulin-dependent protein kinase IV/protein serine/threonine phosphatase 2A signaling complex.
-
Regulation of HIV gene expression.
-
Regulation of HIV-1 gene expression.
-
Regulation of Sertoli cell differentiation by the testicular paracrine factor PModS: potential role of immediate-early genes.
-
Regulation of T cell receptor delta gene rearrangement by c-Myb.
-
Regulation of alpha-synuclein expression by poly (ADP ribose) polymerase-1 (PARP-1) binding to the NACP-Rep1 polymorphic site upstream of the SNCA gene.
-
Regulation of alpha1G T-type calcium channel gene (CACNA1G) expression during neuronal differentiation.
-
Regulation of alternative splicing of NMDAR1 in the kindling model.
-
Regulation of basement membrane-reactive B cells in BXSB, (NZBxNZW)F1, NZB, and MRL/lpr lupus mice.
-
Regulation of eukaryotic initiation factor 4E (eIF4E) phosphorylation by mitogen-activated protein kinase occurs through modulation of Mnk1-eIF4G interaction.
-
Regulation of gene expression in the human immunodeficiency virus type 1.
-
Regulation of gonadotropin-releasing hormone by protein kinase-A and -C in immortalized hypothalamic neurons.
-
Regulation of group VIA phospholipase A2 expression by sterol availability.
-
Regulation of hormone metabolism in Arabidopsis seeds: phytochrome regulation of abscisic acid metabolism and abscisic acid regulation of gibberellin metabolism.
-
Regulation of human CD44H and CD44E isoform binding to hyaluronan by phorbol myristate acetate and anti-CD44 monoclonal and polyclonal antibodies.
-
Regulation of human immunodeficiency virus replication.
-
Regulation of human retroviral latency by the NF-kappa B/I kappa B family: inhibition of human immunodeficiency virus replication by I kappa B through a Rev-dependent mechanism.
-
Regulation of leukocyte rolling and adhesion to high endothelial venules through the cytoplasmic domain of L-selectin.
-
Regulation of membrane targeting of the G protein-coupled receptor kinase 2 by protein kinase A and its anchoring protein AKAP79.
-
Regulation of mitotic homeologous recombination in yeast. Functions of mismatch repair and nucleotide excision repair genes.
-
Regulation of streptokinase expression by CovR/S in Streptococcus pyogenes: CovR acts through a single high-affinity binding site.
-
Regulation of the Escherichia coli HipBA toxin-antitoxin system by proteolysis.
-
Regulation of the T-cell receptor delta enhancer by functional cooperation between c-Myb and core-binding factors.
-
Regulation of the fate of human mesenchymal stem cells by mechanical and stereo-topographical cues provided by silicon nanowires.
-
Regulation of the human c-myc gene: 5' noncoding sequences do not affect translation.
-
Regulation of the human interleukin-3 gene.
-
Regulation of the metastasis suppressor gene MKK4 in ovarian cancer.
-
Regulation of the platelet-derived growth factor receptor-beta by G protein-coupled receptor kinase-5 in vascular smooth muscle cells involves the phosphatase Shp2.
-
Regulation of the uncoupling protein gene (Ucp) by beta 1, beta 2, and beta 3-adrenergic receptor subtypes in immortalized brown adipose cell lines.
-
Regulation of the uncoupling protein-2 gene in INS-1 beta-cells by oleic acid.
-
Regulation of trabecular meshwork cell contraction and intraocular pressure by miR-200c.
-
Regulation of type II adenylyl cyclase mRNA in rabbit skeletal muscle by chronic motor nerve pacing.
-
Regulation of vitellogenin gene expression in transgenic Caenorhabditis elegans: short sequences required for activation of the vit-2 promoter.
-
Regulatory and structural motifs of chicken gizzard myosin light chain kinase.
-
Regulatory elements governing transcription in specialized myofiber subtypes.
-
Regulatory interactions between the Reg1-Glc7 protein phosphatase and the Snf1 protein kinase.
-
Relations between deletion polymorphism of the angiotensin-converting enzyme gene and insulin resistance, glucose intolerance, hyperinsulinemia, and dyslipidemia.
-
Relationship between radiation-induced G1 phase arrest and p53 function in human tumor cells.
-
Relationship of the glyoxylate pathway to the pathogenesis of Cryptococcus neoformans.
-
Relationships among DNA sequences of the 1.3 kb EcoRI family of mouse DNA.
-
Relative expression of aromatase cytochrome P450 in human fetal tissues as determined by competitive polymerase chain reaction amplification.
-
Remarkable conservation of structure among intermediate filament genes.
-
Removal of frameshift intermediates by mismatch repair proteins in Saccharomyces cerevisiae.
-
Renal cell carcinoma development in the rat independent of alterations at the VHL gene locus.
-
Repair of double-strand breaks in bacteriophage T4 by a mechanism that involves extensive DNA replication.
-
Repair of large insertion/deletion heterologies in human nuclear extracts is directed by a 5' single-strand break and is independent of the mismatch repair system.
-
Repair of topoisomerase-mediated DNA damage in bacteriophage T4.
-
Replication and compartmentalization of HIV-1 in kidney epithelium of patients with HIV-associated nephropathy.
-
Replication factors MCM2 and ORC1 interact with the histone acetyltransferase HBO1.
-
Replication of N2-ethyldeoxyguanosine DNA adducts in the human embryonic kidney cell line 293.
-
Report and abstracts of the 4th International Workshop on Chromosome 9. Williamsburg, Virginia, USA, April 23-25, 1995.
-
Repression of yeast Ste12 transcription factor by direct binding of unphosphorylated Kss1 MAPK and its regulation by the Ste7 MEK.
-
Requirement for d(GATC) sequences in Escherichia coli mutHLS mismatch correction.
-
Requirement of MIP-1 alpha for an inflammatory response to viral infection.
-
Requirement of transforming growth factor-beta (TGF-beta) type II receptor for TGF-beta-induced proliferation and growth inhibition.
-
Rescuing dicer defects via inhibition of an anti-dicing nuclease.
-
Residues within a conserved amino acid motif of domains 1 and 4 of VCAM-1 are required for binding to VLA-4.
-
Resistance to infection, early and persistent suppression of simian immunodeficiency virus SIVmac251 viremia, and significant reduction of tissue viral burden after mucosal vaccination in female rhesus macaques.
-
Resolving Heart Regeneration by Replacement Histone Profiling.
-
Resolving fast and slow motions in the internal loop containing stem-loop 1 of HIV-1 that are modulated by Mg2+ binding: role in the kissing-duplex structural transition.
-
Resolving sugar puckers in RNA excited states exposes slow modes of repuckering dynamics.
-
Restricted expression of type-II TGF beta receptor in murine embryonic development suggests a central role in tissue modeling and CNS patterning.
-
Retargeting mobile group II introns to repair mutant genes.
-
Retina- and ventral forebrain-specific Cre recombinase activity in transgenic mice.
-
Retina-specifically expressed novel subtypes of bovine cyclophilin.
-
Retinal degeneration in the rd mouse is caused by a defect in the beta subunit of rod cGMP-phosphodiesterase.
-
Retinoic acid modulation of alpha(1-->2) fucosyltransferase activity and sensitivity of tumor cells to LAK-mediated cytotoxicity.
-
Retinoic acid receptors: transcription factors modulating gene regulation, development, and differentiation.
-
Retinoids and mouse embryonic development.
-
Retrotransposon insertion polymorphisms in six rice genes and their evolutionary history.
-
Retrotransposons Are the Major Contributors to the Expansion of the Drosophila ananassae Muller F Element.
-
Retroviral gene transduction of circulating progenitor cells in patients with metastatic breast cancer.
-
Retroviruses as model systems for the study of nuclear RNA export pathways.
-
Revealing A-T and G-C Hoogsteen base pairs in stressed protein-bound duplex DNA.
-
Revealing noncovalent interactions.
-
Reversion and T cell escape mutations compensate the fitness loss of a CD8+ T cell escape mutant in their cognate transmitted/founder virus.
-
Rho GTPase inactivation impairs lens growth and integrity.
-
Ribotrap : targeted purification of RNA-specific RNPs from cell lysates through immunoaffinity precipitation to identify regulatory proteins and RNAs.
-
Ribozyme activity in the genomic and antigenomic RNA strands of hepatitis delta virus.
-
Ribozyme cleavage of a 2,5-phosphodiester linkage: mechanism and a restricted divalent metal-ion requirement.
-
Ribozyme-mediated repair of defective mRNA by targeted, trans-splicing.
-
Role for ETS domain transcription factors Pea3/Erm in mouse lung development.
-
Role for topoisomerase 1 in transcription-associated mutagenesis in yeast.
-
Role of Conformational Fluctuations of Protein toward Methylation in DNA by Cytosine-5-methyltransferase.
-
Role of alternative oxidase gene in pathogenesis of Cryptococcus neoformans.
-
Role of autonomous androgen receptor signaling in prostate cancer initiation is dichotomous and depends on the oncogenic signal.
-
Role of conserved gp41 cysteine residues in the processing of human immunodeficiency virus envelope precursor and viral infectivity.
-
Role of nucleobase energetics and nucleobase interactions in single-stranded peptide nucleic acid charge transfer.
-
Role of peroxisome proliferator-activated receptor alpha in disease of pancreatic beta cells.
-
Role of the 2-amino group of deoxyguanosine in sequence recognition by EcoRI restriction and modification enzymes.
-
Role of the avian retrovirus mRNA leader in expression: evidence for novel translational control.
-
Role of ubiquitin-like protein FAT10 in epithelial apoptosis in renal disease.
-
Roles for inositol-phosphoryl ceramide synthase 1 (IPC1) in pathogenesis of C. neoformans.
-
Roles of 3,5,3'-triiodothyronine and deoxyribonucleic acid binding on thyroid hormone receptor complex formation.
-
Roles of RAD6 epistasis group members in spontaneous polzeta-dependent translesion synthesis in Saccharomyces cerevisiae.
-
Roles of v-erbA homodimers and heterodimers in mediating dominant negative activity by v-erbA.
-
Rotavirus RNA polymerase requires the core shell protein to synthesize the double-stranded RNA genome.
-
S-allele sequence diversity in natural populations of Solanum carolinense (Horsenettle).
-
S-nitrosylation of heterogeneous nuclear ribonucleoprotein A/B regulates osteopontin transcription in endotoxin-stimulated murine macrophages.
-
SAMP14, a novel, acrosomal membrane-associated, glycosylphosphatidylinositol-anchored member of the Ly-6/urokinase-type plasminogen activator receptor superfamily with a role in sperm-egg interaction.
-
SLCO4C1 transporter eliminates uremic toxins and attenuates hypertension and renal inflammation.
-
STAT1 is essential for antimicrobial effector function but dispensable for gamma interferon production during Toxoplasma gondii infection.
-
SVA: software for annotating and visualizing sequenced human genomes.
-
Saccharomyces cerevisiae Ntg1p and Ntg2p: broad specificity N-glycosylases for the repair of oxidative DNA damage in the nucleus and mitochondria.
-
Saccharomyces cerevisiae RAD5-encoded DNA repair protein contains DNA helicase and zinc-binding sequence motifs and affects the stability of simple repetitive sequences in the genome.
-
Sakacin P non-producing Lactobacillus sakei strains contain homologues of the sakacin P gene cluster.
-
Satellite DNA sequences of Drosophila melanogaster.
-
Saturation mutagenesis of His114 of EcoRI reveals relaxed-specificity mutants.
-
Scar/WAVE-1, a Wiskott-Aldrich syndrome protein, assembles an actin-associated multi-kinase scaffold.
-
Screening the human exome: a comparison of whole genome and whole transcriptome sequencing.
-
Secondary structure creates mismatched base pairs required for high-affinity binding of cAMP response element-binding protein to the human enkephalin enhancer.
-
Secondary structure of ovalbumin messenger RNA.
-
Secondary structure of the self-cleaving RNA of hepatitis delta virus: applications to catalytic RNA design.
-
Secreted extracellular domains of macrophage scavenger receptors form elongated trimers which specifically bind crocidolite asbestos.
-
Secretion of HLA-A and -B antigens via an alternative RNA splicing pathway.
-
Selected contribution: a three-dimensional model for assessment of in vitro toxicity in balaena mysticetus renal tissue.
-
Selection of a subset of mRNAs from combinatorial 3' untranslated region libraries using neuronal RNA-binding protein Hel-N1.
-
Selection of an RNA molecule that mimics a major autoantigenic epitope of human insulin receptor.
-
Selection of circularization sites in a group I IVS RNA requires multiple alignments of an internal template-like sequence.
-
Selective expression of insulin-like growth factor II in the songbird brain.
-
Selective inhibition of Alu retrotransposition by APOBEC3G.
-
Selective mutations in cloned and expressed alpha-macroglobulin receptor binding fragment alter binding to either the alpha2-macroglobulin signaling receptor or the low density lipoprotein receptor-related protein/alpha2-macroglobulin receptor.
-
Selective regulation of expression of protein kinase C beta isoenzymes occurs via alternative splicing.
-
Self-cleavage of hepatitis delta virus genomic strand RNA is enhanced under partially denaturing conditions.
-
Sensing of extracellular cations in CasR-deficient osteoblasts. Evidence for a novel cation-sensing mechanism.
-
Separate domains of the Ran GTPase interact with different factors to regulate nuclear protein import and RNA processing.
-
Separate pathways for p53 induction by ionizing radiation and N-(phosphonoacetyl)-L-aspartate.
-
Sequence analysis and insertional inactivation of a gene encoding Moraxella sp. CK-1 cell wall hydrolase.
-
Sequence analysis of a cDNA for lysyl hydroxylase isolated from human skin fibroblasts from a normal donor: differences from human placental lysyl hydroxylase cDNA.
-
Sequence analysis of the cDNA encoding human liver glycogen phosphorylase reveals tissue-specific codon usage.
-
Sequence and chromosomal location of the I-309 gene. Relationship to genes encoding a family of inflammatory cytokines.
-
Sequence at both termini of the 10 genes of reovirus serotype 3 (strain Dearing).
-
Sequence complexity of nuclear RNAs in adult rat tissues.
-
Sequence complexity of nuclear and cytoplasmic ribonucleic acids from clonal neurotumor cell lines and brain sections of the rat.
-
Sequence composition and context effects on the generation and repair of frameshift intermediates in mononucleotide runs in Saccharomyces cerevisiae.
-
Sequence context of indel mutations and their effect on protein evolution in a bacterial endosymbiont.
-
Sequence divergence impedes crossover more than noncrossover events during mitotic gap repair in yeast.
-
Sequence elements required for transcriptional activity of the human myoglobin promoter in intact myocardium.
-
Sequence features of DNA binding sites reveal structural class of associated transcription factor.
-
Sequence of full length cDNA for human S-adenosylhomocysteine hydrolase.
-
Sequence of terminal regions of cowpox virus DNA: arrangement of repeated and unique sequence elements.
-
Sequence requirements for micro RNA processing and function in human cells.
-
Sequence variation in the transforming growth factor-beta1 (TGFB1) gene and multiple sclerosis susceptibility.
-
Sequence-based differentiation of strains in the Mycobacterium avium complex.
-
Sequence-independent method for in vitro generation of nested deletions for sequencing large DNA fragments.
-
Sequence-specific B-DNA flexibility modulates Z-DNA formation.
-
Sequence-specific contacts between the RNA polymerase of vesicular stomatitis virus and the leader RNA gene.
-
Sequences and phylogenetic analysis of the nef gene from Thai subjects harboring subtype E HIV-1.
-
Sequences flanking the pentanucleotide T-antigen binding sites in the polyomavirus core origin help determine selectivity of DNA replication.
-
Sequences that direct rat tyrosine hydroxylase gene expression.
-
Sequences within the spacer region of yeast rRNA cistrons that stimulate 35S rRNA synthesis in vivo mediate RNA polymerase I-dependent promoter and terminator activities.
-
Sequencing and analysis of genomic fragments from the NF1 locus.
-
Sequencing of laminin B chain cDNAs reveals C-terminal regions of coiled-coil alpha-helix.
-
Seven-base-pair inverted repeats in DNA form stable hairpins in vivo in Saccharomyces cerevisiae.
-
Seven-up inhibits ultraspiracle-based signaling pathways in vitro and in vivo.
-
Sex dependent glial-specific changes in the chromatin accessibility landscape in late-onset Alzheimer's disease brains.
-
Sex-specific fitness effects of unpredictable early life conditions are associated with DNA methylation in the avian glucocorticoid receptor.
-
Sexual cycle of Cryptococcus neoformans var. grubii and virulence of congenic a and alpha isolates.
-
Shared genetic pathways contribute to the tolerance of endogenous and low-dose exogenous DNA damage in yeast.
-
Shortening the HIV-1 TAR RNA Bulge by a Single Nucleotide Preserves Motional Modes over a Broad Range of Time Scales.
-
Signal sequence- and translation-independent mRNA localization to the endoplasmic reticulum.
-
Signaling activities of the Drosophila wingless gene are separately mutable and appear to be transduced at the cell surface.
-
Signatures of protein-DNA recognition in free DNA binding sites.
-
Simian immunodeficiency virus (SIV) envelope-specific Fabs with high-level homologous neutralizing activity: recovery from a long-term-nonprogressor SIV-infected macaque.
-
Simian immunodeficiency virus DNA vaccine trial in macaques.
-
Simple Mendelian inheritance of the reiterated ribosomal DNA of yeast.
-
Simple Mendelian inheritance of the repeating yeast ribosomal DNA genes.
-
Simultaneous amplification of four DNA repair genes and beta-actin in human lymphocytes by multiplex reverse transcriptase-PCR.
-
Single intraluminal delivery of antisense cdc2 kinase and proliferating-cell nuclear antigen oligonucleotides results in chronic inhibition of neointimal hyperplasia.
-
Single origin and subsequent diversification of central Andean endemic Umbilicaria species.
-
Single-cell RNA Sequencing of Fluorescently Labeled Mouse Neurons Using Manual Sorting and Double In Vitro Transcription with Absolute Counts Sequencing (DIVA-Seq).
-
Site on the vesicular stomatitis virus genome specifying polyadenylation and the end of the L gene mRNA.
-
Site-directed mutagenesis of the inhibitory subunit of retinal rod cyclic GMP phosphodiesterase.
-
Site-specific RNA cleavage generates the 3' end of a poxvirus late mRNA.
-
Site-specific integration of the Haemophilus influenzae bacteriophage HP1. Identification of the points of recombinational strand exchange and the limits of the host attachment site.
-
Site-specific integration of the Haemophilus influenzae bacteriophage HP1: location of the boundaries of the phage attachment site.
-
Site-specific mutagenesis of Drosophila alcohol dehydrogenase: evidence for involvement of tyrosine-152 and lysine-156 in catalysis.
-
Site-specific mutations alter in vitro factor binding and change promoter expression pattern in transgenic plants.
-
Site-specific retinoic acid production in the brain of adult songbirds.
-
Sites of P element insertion and structures of P element deletions in the 5' region of Drosophila melanogaster RpII215.
-
Sites of circularization of the Tetrahymena rRNA IVS are determined by sequence and influenced by position and secondary structure.
-
Sites of copy choice replication involved in generation of vesicular stomatitis virus defective-interfering particle RNAs.
-
Sites of interaction between kinase-related protein and smooth muscle myosin.
-
Six novel mutations in the endoglin gene in hereditary hemorrhagic telangiectasia type 1 suggest a dominant-negative effect of receptor function.
-
Slip into something more functional: selection maintains ancient frameshifts in homopolymeric sequences.
-
Slow algae, fast fungi: exceptionally high nucleotide substitution rate differences between lichenized fungi Omphalina and their symbiotic green algae Coccomyxa.
-
Slowdown of Interhelical Motions Induces a Glass Transition in RNA.
-
Smad3-Smad4 and AP-1 complexes synergize in transcriptional activation of the c-Jun promoter by transforming growth factor beta.
-
Smad3-dependent nuclear translocation of beta-catenin is required for TGF-beta1-induced proliferation of bone marrow-derived adult human mesenchymal stem cells.
-
Small nucleolar RNAs U32a, U33, and U35a are critical mediators of metabolic stress.
-
Small-molecule inhibition of human immunodeficiency virus type 1 replication by specific targeting of the final step of virion maturation.
-
Solution structure of a pyrimidine-purine-pyrimidine triplex containing the sequence-specific intercalating non-natural base D3.
-
Somatic deletion of the neurofibromatosis type 1 gene in a neurofibrosarcoma supports a tumour suppressor gene hypothesis.
-
Somatic mutations in the BRCA1 gene in sporadic ovarian tumours.
-
Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types.
-
Somatic mutations in the transcriptional corepressor gene BCORL1 in adult acute myelogenous leukemia.
-
Somatic mutations of GUCY2F, EPHA3, and NTRK3 in human cancers.
-
Sour taste responses in mice lacking PKD channels.
-
Sox8 is expressed at similar levels in gonads of both sexes during the sex determining period in turtles.
-
Sp and GATA factors are critical for Apolipoprotein AI downstream enhancer activity in human HepG2 cells.
-
SpHnf6, a transcription factor that executes multiple functions in sea urchin embryogenesis.
-
Spdeadringer, a sea urchin embryo gene required separately in skeletogenic and oral ectoderm gene regulatory networks.
-
Species-specific oligonucleotide probes for rRNA of Clostridium difficile and related species.
-
Specific binding of the human T-cell leukemia virus type I Rex protein to a short RNA sequence located within the Rex-response element.
-
Specific blockade of basic fibroblast growth factor gene expression in endothelial cells by antisense oligonucleotide.
-
Specific induction of endogenous viral restriction factors using CRISPR/Cas-derived transcriptional activators.
-
Specific inhibition of human immunodeficiency virus type 1 replication by antisense oligonucleotides: an in vitro model for treatment.
-
Specific inhibition of protein kinase A in granulosa cells abolishes gonadotropin regulation of the proopiomelanocortin promoter.
-
Specific role for protein kinase C beta in cell differentiation.
-
Specification of epibranchial placodes in zebrafish.
-
Specificity of human bactericidal antibodies against PorA P1.7,16 induced with a hexavalent meningococcal outer membrane vesicle vaccine.
-
Specificity, sensitivity, and predictive value of apolipoprotein-E genotyping for sporadic Alzheimer's disease.
-
Spectrum of mutation and frequency of allelic deletion of the p53 gene in ovarian cancer.
-
Spink2 modulates apoptotic susceptibility and is a candidate gene in the Rgcs1 QTL that affects retinal ganglion cell death after optic nerve damage.
-
Spontaneous deletions and duplications of sequences in the genome of cowpox virus.
-
Spontaneous frameshift mutations in Saccharomyces cerevisiae: accumulation during DNA replication and removal by proofreading and mismatch repair activities.
-
Stabilization of microsatellite sequences by variant repeats in the yeast Saccharomyces cerevisiae.
-
Stable inhibition of hepatitis B virus proteins by small interfering RNA expressed from viral vectors.
-
Stac3 is a component of the excitation-contraction coupling machinery and mutated in Native American myopathy.
-
Stage- and ribosome-specific alterations in nascent chain-Sec61p interactions accompany translocation across the ER membrane.
-
Stage-specific expression of B cell translocation gene 1 in rat testis.
-
Standards recommendations for the Earth BioGenome Project.
-
Statistical analysis of RNA backbone.
-
Statistical evaluation of the Rodin-Ohno hypothesis: sense/antisense coding of ancestral class I and II aminoacyl-tRNA synthetases.
-
Steroid hormone regulation of specific messenger RNA and protein synthesis in eucaryotic cells.
-
Stimulation of human and rat islet beta-cell proliferation with retention of function by the homeodomain transcription factor Nkx6.1.
-
Stimulation of murine lymphocyte proliferation by a phosphorothioate oligonucleotide with antisense activity for herpes simplex virus.
-
Stimulation of slow skeletal muscle fiber gene expression by calcineurin in vivo.
-
Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines.
-
Strand-specific mismatch repair in mammalian cells.
-
Stress affects uterine receptivity through an ovarian-independent pathway.
-
Stress proteins and cardiovascular disease.
-
Stringent comparative sequence analysis reveals SOX10 as a putative inhibitor of glial cell differentiation.
-
Stromelysin-3 is overexpressed by stromal elements in primary non-small cell lung cancers and regulated by retinoic acid in pulmonary fibroblasts.
-
Structural alterations of the epidermal growth factor receptor gene in human gliomas.
-
Structural analysis of the functional sites of class I HLA antigens.
-
Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch.
-
Structural and functional analysis of the avian leukemia virus constitutive transport element.
-
Structural and functional analysis of the visna virus Rev-response element.
-
Structural and functional characterization of monomeric soluble P-selectin and comparison with membrane P-selectin.
-
Structural and functional domains of the Drosophila ncd microtubule motor protein.
-
Structural and functional dynamics of human centromeric chromatin.
-
Structural and immunological comparison of indigenous human O6-methylguanine-DNA methyltransferase with that encoded by a cloned cDNA.
-
Structural and signaling requirements for BCR-ABL-mediated transformation and inhibition of apoptosis.
-
Structural basis for SH2D1A mutations in X-linked lymphoproliferative disease.
-
Structural basis of core promoter recognition in a primitive eukaryote.
-
Structural basis of pilus subunit recognition by the PapD chaperone.
-
Structural characterization of the 5' regions of the human phenylalanine hydroxylase gene.
-
Structural comparison of the free and DNA-bound forms of the purine repressor DNA-binding domain.
-
Structural components of rna tumor viruses.
-
Structural determinants of insert retention of poliovirus expression vectors with recombinant IRES elements.
-
Structural features of nephritogenic lupus autoantibodies.
-
Structural organization and chromosomal assignment of the parvalbumin gene.
-
Structural organization and regulation of the chicken estrogen receptor.
-
Structural organization of the human MS4A gene cluster on Chromosome 11q12.
-
Structural relationships in glycogen phosphorylases.
-
Structural requirements for pre-microRNA binding and nuclear export by Exportin 5.
-
Structurally distinct and stage-specific adenylyl cyclase genes play different roles in Dictyostelium development.
-
Structurally divergent human T cell receptor gamma proteins encoded by distinct C gamma genes.
-
Structure and domain organization of the CD19 antigen of human, mouse, and guinea pig B lymphocytes. Conservation of the extensive cytoplasmic domain.
-
Structure and expression of a membrane component of the inhibin receptor system.
-
Structure and function of anti-DNA autoantibodies derived from a single autoimmune mouse.
-
Structure and function of the UvrB protein.
-
Structure and function of the ovine type 1 corticotropin releasing factor receptor (CRF1) and a carboxyl-terminal variant.
-
Structure and regulation of G protein-coupled receptors: the beta 2-adrenergic receptor as a model.
-
Structure and regulation of the chicken erythroid delta-aminolevulinate synthase gene.
-
Structure and regulation of the mouse ing1 gene. Three alternative transcripts encode two phd finger proteins that have opposite effects on p53 function.
-
Structure of DNA polymerase I Klenow fragment bound to duplex DNA.
-
Structure of FitAB from Neisseria gonorrhoeae bound to DNA reveals a tetramer of toxin-antitoxin heterodimers containing pin domains and ribbon-helix-helix motifs.
-
Structure of a G.T.A triplet in an intramolecular DNA triplex.
-
Structure of the CD59-encoding gene: further evidence of a relationship to murine lymphocyte antigen Ly-6 protein.
-
Structure of the eukaryotic transcription apparatus: features of the gene for the largest subunit of Drosophila RNA polymerase II.
-
Structure of the gene encoding the human B lymphocyte differentiation antigen CD20 (B1).
-
Structure of the gene encoding the human leukocyte adhesion molecule-1 (TQ1, Leu-8) of lymphocytes and neutrophils.
-
Structure of the genes encoding the CD19 antigen of human and mouse B lymphocytes.
-
Structure of the genes encoding transcription factor IIB and TATA box-binding protein from Drosophila melanogaster.
-
Structure of the human allelic glutathione S-transferase-pi gene variant, hGSTP1 C, cloned from a glioblastoma multiforme cell line.
-
Structure of the human gene (COX6A2) for the heart/muscle isoform of cytochrome c oxidase subunit VIa and its chromosomal location in humans, mice, and cattle.
-
Structure, chromosome location, and expression of the human gamma-actin gene: differential evolution, location, and expression of the cytoskeletal beta- and gamma-actin genes.
-
Structure-based engineering of environmentally sensitive fluorophores for monitoring protein-protein interactions.
-
Structure-function analyses of the HTLV-I Rex and HIV-1 Rev RNA response elements: insights into the mechanism of Rex and Rev action.
-
Structures and mechanisms of DNA restriction and modification enzymes.
-
Structures involved in Tetrahymena rRNA self-splicing and RNA enzyme activity.
-
Structures of ParB bound to DNA reveal mechanism of partition complex formation.
-
Structures of carbon catabolite protein A-(HPr-Ser46-P) bound to diverse catabolite response element sites reveal the basis for high-affinity binding to degenerate DNA operators.
-
Structures of mismatch replication errors observed in a DNA polymerase.
-
Studies leading to the isolation of a cDNA for the gene causing retinal degeneration in the rd mouse.
-
Studies of the regulatory mechanism of Ca2+/calmodulin-dependent protein kinase II. Mutation of threonine 286 to alanine and aspartate.
-
Studies on sequence recognition by type II restriction and modification enzymes.
-
Studies on the repression of basal transcription (silencing) by artificial and natural human thyroid hormone receptor-beta mutants.
-
Study of a US cohort supports the role of ZNF644 and high-grade myopia susceptibility.
-
Study of the kinetic and physical properties of the orotidine-5'-monophosphate decarboxylase domain from mouse UMP synthase produced in Saccharomyces cerevisiae.
-
Subcellular partitioning of MRP RNA assessed by ultrastructural and biochemical analysis.
-
Subglutinol A, an immunosuppressive α-pyrone diterpenoid from Fusarium subglutinans, acts as an estrogen receptor antagonist.
-
Subspecific differentiation of Mycobacterium avium complex strains by automated sequencing of a region of the gene (hsp65) encoding a 65-kilodalton heat shock protein.
-
Substrate dependence of the mechanism of EcoRI endonuclease.
-
Substrate length requirements for efficient mitotic recombination in Saccharomyces cerevisiae.
-
Substrate recognition by the EcoRI endonuclease.
-
Substrate spectrum of human excinuclease: repair of abasic sites, methylated bases, mismatches, and bulky adducts.
-
Successful herbivore attack due to metabolic diversion of a plant chemical defense.
-
Sulfotransferases of two specificities function in the reconstitution of high endothelial cell ligands for L-selectin.
-
Superimmunity: characterization of a new gene in the immunity region of P1.
-
Superoxide enhances interleukin 1beta-mediated transcription of the hepatocyte-inducible nitric oxide synthase gene.
-
Suppression subtractive hybridization: a method for generating differentially regulated or tissue-specific cDNA probes and libraries.
-
Suppression subtractive hybridization: a versatile method for identifying differentially expressed genes.
-
Suppressor and activator functions mediated by a repeated heptad sequence in the liver fatty acid-binding protein gene (Fabpl). Effects on renal, small intestinal, and colonic epithelial cell gene expression in transgenic mice.
-
Surface-enhanced Raman gene probe for HIV detection.
-
Survey of variation in human transcription factors reveals prevalent DNA binding changes.
-
Sutterella wadsworthensis gen. nov., sp. nov., bile-resistant microaerophilic Campylobacter gracilis-like clinical isolates.
-
Synergistic derepression of gibberellin signaling by removing RGA and GAI function in Arabidopsis thaliana.
-
Synergistic induction of mitogen-activated protein kinase phosphatase-1 by thrombin and epidermal growth factor requires vascular endothelial growth factor receptor-2.
-
Synergistic interactions between heterologous upstream activation elements and specific TATA sequences in a muscle-specific promoter.
-
Synthesis of DNA coding for human proinsulin.
-
Synthesis of single-stranded hybridization probes from reusable DNA templates bound to solid support.
-
Synthetic microRNA designed to target glioma-associated antigen 1 transcription factor inhibits division and induces late apoptosis in pancreatic tumor cells.
-
Systemic administration of HVJ viral coat-liposome complex containing human insulin vector decreases glucose level in diabetic mouse: A model of gene therapy.
-
T cell CD7 mRNA expression is regulated by both transcriptional and post-transcriptional mechanisms.
-
T-Cell receptor Vbeta repertoire CDR3 length diversity differs within CD45RA and CD45RO T-cell subsets in healthy and human immunodeficiency virus-infected children.
-
T296----M, a common mutation causing mild hemophilia B in the Amish and others: founder effect, variability in factor IX activity assays, and rapid carrier detection.
-
TBestDB: a taxonomically broad database of expressed sequence tags (ESTs).
-
TGF-beta regulates expression of tenascin alternative-splicing isoforms in fetal rat lung.
-
TIA nuclear proteins regulate the alternate splicing of lysyl hydroxylase 2.
-
TOR mutations confer rapamycin resistance by preventing interaction with FKBP12-rapamycin.
-
TP53 and RAS mutations in metachronous tumors from patients with cancer of the upper aerodigestive tract.
-
TP53 intron 1 hotspot rearrangements are specific to sporadic osteosarcoma and can cause Li-Fraumeni syndrome.
-
Tagging ribozyme reaction sites to follow trans-splicing in mammalian cells.
-
Tagging single nucleotide polymorphisms in excision repair cross-complementing group 1 (ERCC1) and risk of primary lung cancer in a Chinese population.
-
Tandemly arranged variant 5S ribosomal RNA genes in the yeast Saccharomyces cerevisiae.
-
Tandemly repeated sequences are present at the ends of the DNA of raccoonpox virus.
-
Targeted deletion of 5'HS2 of the murine beta-globin LCR reveals that it is not essential for proper regulation of the beta-globin locus.
-
Targeted deletion of angiotensin II type 1A receptor does not protect mice from progressive nephropathy of overload proteinuria.
-
Targeted gene replacement demonstrates that myristoyl-CoA: protein N-myristoyltransferase is essential for viability of Cryptococcus neoformans.
-
Targeting RNA with cysteine-constrained peptides.
-
Targeting RNA with small molecules: from fundamental principles towards the clinic.
-
Targeting Two Coagulation Cascade Proteases with a Bivalent Aptamer Yields a Potent and Antidote-Controllable Anticoagulant.
-
Targeting a genetically engineered elastin-like polypeptide to solid tumors by local hyperthermia.
-
Targeting protein phosphatase 1 (PP1) to the actin cytoskeleton: the neurabin I/PP1 complex regulates cell morphology.
-
Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast.
-
Targets of immunophilin-immunosuppressant complexes are distinct highly conserved regions of calcineurin A.
-
TbetaRIII suppresses non-small cell lung cancer invasiveness and tumorigenicity.
-
Tcra gene recombination is supported by a Tcra enhancer- and CTCF-dependent chromatin hub.
-
Telomerase activity in normal leukocytes and in hematologic malignancies.
-
Telomere shortening in formerly abused and never abused women
-
Temperature-sensitive SV40 immortalized rat proximal tubule cell line has functional renin-angiotensin system.
-
Temperature-sensitive mutations in the III-IV cytoplasmic loop region of the skeletal muscle sodium channel gene in paramyotonia congenita.
-
Ten nucleotide differences, five of which cause amino acid changes, are associated with the Ah receptor locus polymorphism of C57BL/6 and DBA/2 mice.
-
Terminal sequences of vesicular stomatitis virus RNA are both complementary and conserved.
-
Testing morphological concepts of orders of pleurocarpous mosses (Bryophyta) using phylogenetic reconstructions based on TRNL-TRNF and RPS4 sequences.
-
Tethering ribozymes to a retroviral packaging signal for destruction of viral RNA.
-
The 40-kilodalton allergen of Candida albicans is an alcohol dehydrogenase: molecular cloning and immunological analysis using monoclonal antibodies.
-
The 5' non-coding region of the BCR/ABL oncogene augments its ability to stimulate the growth of immature lymphoid cells.
-
The 5'-untranslated region of the N-methyl-D-aspartate receptor NR2A subunit controls efficiency of translation.
-
The 70-kDa heat shock cognate protein (Hsc73) gene is enhanced by ovarian hormones in the ventromedial hypothalamus.
-
The 8.5-kb PstI allele of the stress protein gene, Hsp70-2: an independent risk factor for systemic lupus erythematosus in African Americans?
-
The 9-1-1 checkpoint clamp physically interacts with polzeta and is partially required for spontaneous polzeta-dependent mutagenesis in Saccharomyces cerevisiae.
-
The A and B isoforms of the human progesterone receptor operate through distinct signaling pathways within target cells.
-
The AZFc region of the Y chromosome features massive palindromes and uniform recurrent deletions in infertile men.
-
The Arabidopsis GA1 locus encodes the cyclase ent-kaurene synthetase A of gibberellin biosynthesis.
-
The Arabidopsis SLEEPY1 gene encodes a putative F-box subunit of an SCF E3 ubiquitin ligase.
-
The B56 family of protein phosphatase 2A (PP2A) regulatory subunits encodes differentiation-induced phosphoproteins that target PP2A to both nucleus and cytoplasm.
-
The Bel-1 protein of human foamy virus activates human immunodeficiency virus type 1 gene expression via a novel DNA target site.
-
The CovR response regulator of group A streptococcus (GAS) acts directly to repress its own promoter.
-
The DAZ gene cluster on the human Y chromosome arose from an autosomal gene that was transposed, repeatedly amplified and pruned.
-
The DNA binding domain of a papillomavirus E2 protein programs a chimeric nuclease to cleave integrated human papillomavirus DNA in HeLa cervical carcinoma cells.
-
The DNA sequence and biological annotation of human chromosome 1.
-
The DPE, a conserved downstream core promoter element that is functionally analogous to the TATA box.
-
The Dh gene of Drosophila melanogaster encodes a diuretic peptide that acts through cyclic AMP.
-
The Drosophila Translational Control Element (TCE) is required for high-level transcription of many genes that are specifically expressed in testes.
-
The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal.
-
The Earth BioGenome Project 2020: Starting the clock.
-
The Ehlers-Danlos syndromes.
-
The G protein-coupled receptor GPR4 suppresses ERK activation in a ligand-independent manner.
-
The Genetic Basis of Hepatosplenic T-cell Lymphoma.
-
The HB-6, CDw75, and CD76 differentiation antigens are unique cell-surface carbohydrate determinants generated by the beta-galactoside alpha 2,6-sialyltransferase.
-
The HIV-1 Rev protein: prototype of a novel class of eukaryotic post-transcriptional regulators.
-
The HIV-1 Tat protein: an RNA sequence-specific processivity factor?
-
The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA.
-
The HrpZ proteins of Pseudomonas syringae pvs. syringae, glycinea, and tomato are encoded by an operon containing Yersinia ysc homologs and elicit the hypersensitive response in tomato but not soybean.
-
The ICP0 protein of equine herpesvirus 1 is an early protein that independently transactivates expression of all classes of viral promoters.
-
The International HapMap Project.
-
The LS locus of pea encodes the gibberellin biosynthesis enzyme ent-kaurene synthase A.
-
The Lutheran glycoprotein: a multifunctional adhesion receptor.
-
The MTE, a new core promoter element for transcription by RNA polymerase II.
-
The MerR-like protein BldC binds DNA direct repeats as cooperative multimers to regulate Streptomyces development.
-
The MotA protein from bacteriophage T4 contains two domains. Preliminary structural analysis by X-ray diffraction and nuclear magnetic resonance.
-
The Mutation Profile of SARS-CoV-2 Is Primarily Shaped by the Host Antiviral Defense.
-
The N2-ethylguanine and the O6-ethyl- and O6-methylguanine lesions in DNA: contrasting responses from the "bypass" DNA polymerase eta and the replicative DNA polymerase alpha.
-
The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins.
-
The Oct-2 transcription factor represses tyrosine hydroxylase expression via a heptamer TAATGARAT-like motif in the gene promoter.
-
The Phycomyces madA gene encodes a blue-light photoreceptor for phototropism and other light responses.
-
The Pseudomonas syringae pv. syringae 61 hrpH product, an envelope protein required for elicitation of the hypersensitive response in plants.
-
The QPCR assay for analysis of mitochondrial DNA damage, repair, and relative copy number.
-
The RNA-binding protein DND1 acts sequentially as a negative regulator of pluripotency and a positive regulator of epigenetic modifiers required for germ cell reprogramming.
-
The Role of Brachyruy (T) During Gastrulations Movement in the Sea Urchin, Lytechinus variegatus
-
The SABRE gene is required for normal cell expansion in Arabidopsis.
-
The SCARECROW gene regulates an asymmetric cell division that is essential for generating the radial organization of the Arabidopsis root.
-
The SH2 domains of Stat1 and Stat2 mediate multiple interactions in the transduction of IFN-alpha signals.
-
The SHORT-ROOT gene controls radial patterning of the Arabidopsis root through radial signaling.
-
The STE12alpha homolog is required for haploid filamentation but largely dispensable for mating and virulence in Cryptococcus neoformans.
-
The SV40 core sequence functions as a repressor element in yeast.
-
The Saccharomyces cerevisiae suppressor of choline sensitivity (SCS2) gene is a multicopy Suppressor of mec1 telomeric silencing defects.
-
The Smads: transcriptional regulation and mouse models.
-
The Sox10(Dom) mouse: modeling the genetic variation of Waardenburg-Shah (WS4) syndrome.
-
The Structure of the Biofilm-controlling Response Regulator BfmR from Acinetobacter baumannii Reveals Details of Its DNA-binding Mechanism.
-
The TCT motif, a key component of an RNA polymerase II transcription system for the translational machinery.
-
The Ter mutation in the dead end gene causes germ cell loss and testicular germ cell tumours.
-
The Tetrahymena ribozyme acts like an RNA restriction endonuclease.
-
The U1 RNA-binding site of the U1 small nuclear ribonucleoprotein (snRNP)-associated A protein suggests a similarity with U2 snRNPs.
-
The VP16 transcription activation domain is functional when targeted to a promoter-proximal RNA sequence.
-
The acidic domain of the hepatitis C virus NS4A protein is required for viral assembly and envelopment through interactions with the viral E1 glycoprotein.
-
The actin gene from Cryptococcus neoformans: structure and phylogenetic analysis.
-
The agent of bacillary angiomatosis.
-
The alpha 1C-adrenoceptor in human prostate: cloning, functional expression, and localization to specific prostatic cell types.
-
The androgen-binding protein gene is expressed in CD1 mouse testis.
-
The angiotensin II type 2 (AT2) receptor antagonizes the growth effects of the AT1 receptor: gain-of-function study using gene transfer.
-
The anti-La response of a single MRL/Mp-lpr/lpr mouse: specificity for DNA and VH gene usage.
-
The antigen for Hep Par 1 antibody is the urea cycle enzyme carbamoyl phosphate synthetase 1.
-
The aromatase enzyme: from cloning to cancer.
-
The bZIP transcription factor LCR-F1 is essential for mesoderm formation in mouse development.
-
The bacteriophage T4 insertion/substitution vector system. A method for introducing site-specific mutations into the virus chromosome.
-
The basic helix-loop-helix domain of the aryl hydrocarbon receptor nuclear transporter (ARNT) can oligomerize and bind E-box DNA specifically.
-
The binding of anti-DNA antibodies to phosphorothioate oligonucleotides in a solid phase immunoassay.
-
The calmodulin-dependent protein phosphatase catalytic subunit (calcineurin A) is an essential gene in Aspergillus nidulans.
-
The calmodulin-dependent protein phosphatase catalytic subunit (calcineurin A) is an essential gene in Aspergillus nidulans.
-
The carboxyl terminus of the gamma-subunit of rod cGMP phosphodiesterase contains distinct sites of interaction with the enzyme catalytic subunits and the alpha-subunit of transducin.
-
The carboxyl-terminal repeat domain of RNA polymerase II is not required for transcription factor Sp1 to function in vitro.
-
The catalytic subunit of yeast telomerase.
-
The changing molecular epidemiology of HIV type 1 among northern Thai drug users, 1999 to 2002.
-
The characterization of twenty sequenced human genomes.
-
The chemokines IL-8, monocyte chemoattractant protein-1, and I-309 are monomers at physiologically relevant concentrations.
-
The chick ovomucoid gene contains at least six intervening sequences.
-
The clinical significance of tenascin-C splice variant expression in chondrosarcoma.
-
The coiled-coil domain and Tyr177 of bcr are required to induce a murine chronic myelogenous leukemia-like disease by bcr/abl.
-
The colorectal microRNAome.
-
The comparative genomics and complex population history of Papio
baboons.
-
The complete nucleotide sequence of the Vibrio harveyi bacteriophage VHML.
-
The complete sequence of a unique RNA species synthesized by a DI particle of VSV.
-
The conserved dinucleotide AG of the 3' splice site may be recognized twice during in vitro splicing of mammalian mRNA precursors.
-
The crystal structure of the catalytic domain of a eukaryotic guanylate cyclase.
-
The cutaneous T cell lymphoma, mycosis fungoides, is a human T cell lymphotropic virus-associated disease. A study of 50 patients.
-
The cyclic AMP response element directs tyrosine hydroxylase expression in catecholaminergic central and peripheral nervous system cell lines from transgenic mice.
-
The cytoplasmic domain of a disintegrin and metalloproteinase 10 (ADAM10) regulates its constitutive activity but is dispensable for stimulated ADAM10-dependent shedding.
-
The dCMP transferase activity of yeast Rev1 is biologically relevant during the bypass of endogenously generated AP sites.
-
The deafness-associated mitochondrial DNA mutation at position 7445, which affects tRNASer(UCN) precursor processing, has long-range effects on NADH dehydrogenase subunit ND6 gene expression.
-
The dishevelled protein is modified by wingless signaling in Drosophila.
-
The downstream core promoter element, DPE, is conserved from Drosophila to humans and is recognized by TAFII60 of Drosophila.
-
The effect of oxidative metabolism on spontaneous Pol zeta-dependent translesion synthesis in Saccharomyces cerevisiae.
-
The effect of sequence context on spontaneous Polzeta-dependent mutagenesis in Saccharomyces cerevisiae.
-
The effects of HHV-8 vMIP-II on SIVmac251 infection and replication competent and incompetent SIVmac239Delta3 vectors.
-
The evolution of a complex eucaryotic gene.
-
The evolution of homing endonuclease genes and group I introns in nuclear rDNA.
-
The evolution of transcriptional regulation in eukaryotes.
-
The evolutionary history of ferns inferred from 25 low‐copy nuclear genes
-
The favorable IFNL3 genotype escapes mRNA decay mediated by AU-rich elements and hepatitis C virus-induced microRNAs.
-
The feelgood mutation in zebrafish dysregulates COPII-dependent secretion of select extracellular matrix proteins in skeletal morphogenesis.
-
The fruitless gene is required for the proper formation of axonal tracts in the embryonic central nervous system of Drosophila.
-
The gamma delta T cell receptor.
-
The gamma-subunit of the rod photoreceptor cGMP-binding cGMP-specific PDE is expressed in mouse lung.
-
The gene SCL is expressed during early hematopoiesis and encodes a differentiation-related DNA-binding motif.
-
The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis.
-
The gene encoding vitamin K-dependent anticoagulant protein S is expressed in multiple rabbit organs as demonstrated by northern blotting, in situ hybridization, and immunohistochemistry.
-
The genetic architecture of biofilm formation in a clinical isolate of Saccharomyces cerevisiae.
-
The genetic basis of a flower-color polymorphism in the common
-
The genetic landscape of mutations in Burkitt lymphoma.
-
The genomic analysis of erythrocyte microRNA expression in sickle cell diseases.
-
The germinal center: a crucible for lymphocyte selection.
-
The glucocorticoid receptor interacting protein 1 (GRIP1) localizes in discrete nuclear foci that associate with ND10 bodies and are enriched in components of the 26S proteasome.
-
The growth-dependent expression of angiotensin II type 2 receptor is regulated by transcription factors interferon regulatory factor-1 and -2.
-
The hepatitis C virus 3'-untranslated region or a poly(A) tract promote efficient translation subsequent to the initiation phase.
-
The heterosexual human immunodeficiency virus type 1 epidemic in Thailand is caused by an intersubtype (A/E) recombinant of African origin.
-
The histone methylase Set2p and the histone deacetylase Rpd3p repress meiotic recombination at the HIS4 meiotic recombination hotspot in Saccharomyces cerevisiae.
-
The homophilic adhesion molecule sidekick-1 contributes to augmented podocyte aggregation in HIV-associated nephropathy.
-
The human Tap protein is a nuclear mRNA export factor that contains novel RNA-binding and nucleocytoplasmic transport sequences.
-
The human constitutive androstane receptor promotes the differentiation and maturation of hepatic-like cells.
-
The human endogenous retrovirus K Rev response element coincides with a predicted RNA folding region.
-
The human extraocular muscle myosin heavy chain gene (MYH13) maps to the cluster of fast and developmental myosin genes on chromosome 17.
-
The human foamy virus Bel-1 transcription factor is a sequence-specific DNA binding protein.
-
The human gene for mannan-binding lectin-associated serine protease-2 (MASP-2), the effector component of the lectin route of complement activation, is part of a tightly linked gene cluster on chromosome 1p36.2-3.
-
The human gene for the type III isozyme of hexokinase: structure, basal promoter, and evolution.
-
The human keratin genes and their differential expression.
-
The impact of bcl-2 expression and bax deficiency on prostate homeostasis in vivo.
-
The importance of Src homology 2 domain-containing leukocyte phosphoprotein of 76 kilodaltons sterile-alpha motif domain in thymic selection and T-cell activation.
-
The imprinted H19 noncoding RNA is a primary microRNA precursor.
-
The in vivo characterization of translesion synthesis across UV-induced lesions in Saccharomyces cerevisiae: insights into Pol zeta- and Pol eta-dependent frameshift mutagenesis.
-
The inducibly expressed GTPase localizes to the endoplasmic reticulum, independently of GTP binding.
-
The influence of base sequence on the immunological properties of defined oligonucleotides.
-
The influence of base sequence on the immunostimulatory properties of DNA.
-
The initial nucleotide sequence of DNA transcribed from avian myeloblastosis virus 70 S RNA by RNA-dependent DNA polymerase.
-
The isolation and characterization of a novel cDNA demonstrating an altered mRNA level in nontumorigenic Wilms' microcell hybrid cells.
-
The isolation and characterization of cDNA encoding the mouse bifunctional ATP sulfurylase-adenosine 5'-phosphosulfate kinase.
-
The large subunit of the mammalian mitochondrial ribosome. Analysis of the complement of ribosomal proteins present.
-
The leader RNA of vesicular stomatitis virus is bound by a cellular protein reactive with anti-La lupus antibodies.
-
The mast cell-specific expression of a protease gene, RMCP II, is regulated by an enhancer element that binds specifically to mast cell trans-acting factors.
-
The mechanism of RU486 antagonism is dependent on the conformation of the carboxy-terminal tail of the human progesterone receptor.
-
The mechanism of autoantibody production in an autoimmune MRL/lpr mouse.
-
The moderately repetitive DNA sequences of Caenorhabditis elegans do not show short-period interspersion.
-
The molecular basis of class II MHC allelic control of T cell responses.
-
The molecular defect in type IIB von Willebrand disease. Identification of four potential missense mutations within the putative GpIb binding domain.
-
The mouse CD7 gene: identification of a new element common to the human CD7 and mouse Thy-1 promoters.
-
The mouse Cd83 gene: structure, domain organization, and chromosome localization.
-
The mouse Snrpn minimal promoter and its human orthologue: activity and imprinting.
-
The mouse lethal nonagouti (a(x)) mutation deletes the S-adenosylhomocysteine hydrolase (Ahcy) gene.
-
The mouse retinoid-X receptor-gamma gene: genomic organization and evidence for functional isoforms.
-
The murine DUB-1 gene is specifically induced by the betac subunit of interleukin-3 receptor.
-
The murine winged helix transcription factors, Foxc1 and Foxc2, are both required for cardiovascular development and somitogenesis.
-
The natural 5' splice site of simian virus 40 large T antigen can be improved by increasing the base complementarity to U1 RNA.
-
The neuronatin gene resides in a "micro-imprinted" domain on human chromosome 20q11.2.
-
The nontranscribed chicken calmodulin pseudogene cross-hybridizes with mRNA from the slow-muscle troponin C gene.
-
The nuclear receptor steroidogenic factor 1 acts at multiple levels of the reproductive axis.
-
The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.
-
The nucleotide sequence of Saccharomyces cerevisiae chromosome V.
-
The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.
-
The origins of defective interfering particles of the negative-strand RNA viruses.
-
The peripheral myelin protein gene PMP-22 is contained within the Charcot-Marie-Tooth disease type 1A duplication.
-
The plus strand of reovirus gene S2 is identical with its in vitro transcript.
-
The poly(A) site sequence in HDV RNA alters both extent and rate of self-cleavage of the antigenomic ribozyme.
-
The potassium channel MBK1 (Kv1.1) is expressed in the mouse retina.
-
The products of gene I and the overlapping in-frame gene XI are required for filamentous phage assembly.
-
The promoter for the gene encoding the catalytic subunit of rat glucose-6-phosphatase contains two distinct glucose-responsive regions.
-
The promoter of human T-cell leukemia virus type-I is repressed by the immediate-early gene region of human cytomegalovirus in primary blood lymphocytes.
-
The protein expression landscape of the Arabidopsis root.
-
The proto-oncogene bcl-3 encodes an I kappa B protein.
-
The rat thyroid hormone receptor (TR) Deltabeta3 displays cell-, TR isoform-, and thyroid hormone response element-specific actions.
-
The receptor kinase family: primary structure of rhodopsin kinase reveals similarities to the beta-adrenergic receptor kinase.
-
The regulatory light chain of nonmuscle myosin is encoded by spaghetti-squash, a gene required for cytokinesis in Drosophila.
-
The role of Dbf4-dependent protein kinase in DNA polymerase ζ-dependent mutagenesis in Saccharomyces cerevisiae.
-
The role of avian retroviral LTRs in the regulation of gene expression and viral replication.
-
The role of innate immunity in acute allograft rejection after lung transplantation.
-
The role of surface ig binding in the activation of human B cells by phosphorothioate oligodeoxynucleotides.
-
The role of the mismatch repair machinery in regulating mitotic and meiotic recombination between diverged sequences in yeast.
-
The role of the third beta strand in gp120 conformation and neutralization sensitivity of the HIV-1 primary isolate DH012.
-
The same epitope on CD22 of B lymphocytes mediates the adhesion of erythrocytes, T and B lymphocytes, neutrophils, and monocytes.
-
The second-largest subunit of the poxvirus RNA polymerase is similar to the corresponding subunits of procaryotic and eucaryotic RNA polymerases.
-
The secreted metalloprotease ADAMTS20 is required for melanoblast survival.
-
The self-cleaving domain from the genomic RNA of hepatitis delta virus: sequence requirements and the effects of denaturant.
-
The sequence at the termini of four genes of the three reovirus serotypes.
-
The sequence of the CA-SP1 junction accounts for the differential sensitivity of HIV-1 and SIV to the small molecule maturation inhibitor 3-O-{3',3'-dimethylsuccinyl}-betulinic acid.
-
The sequence of the reovirus serotype 3 L3 genome segment which encodes the major core protein lambda 1.
-
The sequences of reovirus serotype 3 genome segments M1 and M3 encoding the minor protein mu 2 and the major nonstructural protein mu NS, respectively.
-
The small subunit of the mammalian mitochondrial ribosome. Identification of the full complement of ribosomal proteins present.
-
The smallest membrane anchoring subunit (QPs3) of bovine heart mitochondrial succinate-ubiquinone reductase. Cloning, sequencing, topology, and Q-binding domain.
-
The specificity of topoisomerase-mediated DNA cleavage defines acridine-induced frameshift specificity within a hotspot in bacteriophage T4.
-
The specificity of topoisomerase-mediated DNA cleavage defines acridine-induced frameshift specificity within a hotspot in bacteriophage T4.
-
The stabilization of repetitive tracts of DNA by variant repeats requires a functional DNA mismatch repair system.
-
The strength and periodicity of D. melanogaster circadian rhythms are differentially affected by alterations in period gene expression.
-
The structural mechanism for transcription activation by MerR family member multidrug transporter activation, N terminus.
-
The structural organization of the chicken calmodulin gene.
-
The structure of a primitive kinetochore.
-
The structure of the trpE, trpD and 5' trpC genes of Bacillus pumilus.
-
The structure of the trpE, trpD and 5' trpC genes of Bacillus pumilus.
-
The suppressor gene scl1+ of Saccharomyces cerevisiae is essential for growth.
-
The surface envelope protein gene region of equine infectious anemia virus is not an important determinant of tropism in vitro.
-
The three-dimensional structure of H-2Db at 2.4 A resolution: implications for antigen-determinant selection.
-
The type I and type II bovine scavenger receptors expressed in Chinese hamster ovary cells are trimeric proteins with collagenous triple helical domains comprising noncovalently associated monomers and Cys83-disulfide-linked dimers.
-
The ubiquitous subunit of erythroid transcription factor NF-E2 is a small basic-leucine zipper protein related to the v-maf oncogene.
-
The uncharacterized gene 1700093K21Rik and flanking regions are correlated with reproductive isolation in the house mouse, Mus musculus.
-
The utility of PacBio circular consensus sequencing for characterizing complex gene families in non-model organisms.
-
The winged helix transcription factor Foxc1a is essential for somitogenesis in zebrafish.
-
The winged-helix DNA-binding motif: another helix-turn-helix takeoff.
-
The yeast HSM3 gene is not involved in DNA mismatch repair in rapidly dividing cells.
-
The yeast carboxyl-terminal repeat domain kinase CTDK-I is a divergent cyclin-cyclin-dependent kinase complex.
-
The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1.
-
Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling.
-
Thermodynamic evaluation of binding interactions in the methionine repressor system of Escherichia coli using isothermal titration calorimetry.
-
Thermodynamic parameters governing interaction of EcoRI endonuclease with specific and nonspecific DNA sequences.
-
Thermosensory and nonthermosensory isoforms of Drosophila melanogaster TRPA1 reveal heat-sensor domains of a thermoTRP Channel.
-
Thirteen Mhc-DQA1 alleles from two populations of baboons.
-
Three amino acid substitutions in domain I of calmodulin prevent the activation of chicken smooth muscle myosin light chain kinase.
-
Three new adenosine deaminase mutations that define a splicing enhancer and cause severe and partial phenotypes: implications for evolution of a CpG hotspot and expression of a transduced ADA cDNA.
-
Three polymorphisms but no disease-causing mutations in the proximal part of the promoter of the phenylalanine hydroxylase gene.
-
Three tightly linked genes encoding human type I keratins: conservation of sequence in the 5'-untranslated leader and 5'-upstream regions of coexpressed keratin genes.
-
Threshold levels of gene expression of the melanoma antigen gp100 correlate with tumor cell recognition by cytotoxic T lymphocytes.
-
Time and distance dependence of reversible polymer bridging followed by single-molecule force spectroscopy.
-
Tissue specificity of a new splice form of the human lysyl hydroxylase 2 gene.
-
Tissue-specific expression from CaMV 35S enhancer subdomains in early stages of plant development.
-
Tissue-specific expression of Ran isoforms in the mouse.
-
Tissue-specific expression of a chicken calmodulin pseudogene lacking intervening sequences.
-
Tissue-specific expression of kallikrein-related genes in the rat.
-
Tissue-specific expression of the rat androgen-binding protein/sex hormone-binding globulin gene in transgenic mice.
-
Tissue-specific transcription of the rat tyrosine hydroxylase gene requires synergy between an AP-1 motif and an overlapping E box-containing dyad.
-
Tn5 insertion specificity is not influenced by IS50 end sequences in target DNA.
-
Tnni3k modifies disease progression in murine models of cardiomyopathy.
-
Topology links RNA secondary structure with global conformation, dynamics, and adaptation.
-
Topology of an amiloride-binding protein.
-
Total Synthesis of a Functional Designer Eukaryotic Chromosome
-
Towards structural genomics of RNA: rapid NMR resonance assignment and simultaneous RNA tertiary structure determination using residual dipolar couplings.
-
Toxin and kinetic profile of rat brain type III sodium channels expressed in Xenopus oocytes.
-
Trans-activating rev protein of the human immunodeficiency virus 1 interacts directly and specifically with its target RNA.
-
Transactivation functions facilitate the disruption of chromatin structure by estrogen receptor derivatives in vivo.
-
Transcript length heterogeneity at the small heat shock protein genes of Drosophila.
-
Transcription factor AP-2 regulates human immunodeficiency virus type 1 gene expression.
-
Transcription factor decoy to study the molecular mechanism of negative regulation of renin gene expression in the liver in vivo.
-
Transcription factors are required for the meiotic recombination hotspot at the HIS4 locus in Saccharomyces cerevisiae.
-
Transcription of a poxvirus early gene is regulated both by a short promoter element and by a transcriptional termination signal controlling transcriptional interference.
-
Transcription of class III genes: formation of preinitiation complexes.
-
Transcription of orthopoxvirus telomeres at late times during infection.
-
Transcription of the RelB gene is regulated by NF-kappaB.
-
Transcription of the terminal loop region of vaccinia virus DNA is initiated from the telomere sequences directing DNA resolution.
-
Transcription-associated mutagenesis in yeast is directly proportional to the level of gene expression and influenced by the direction of DNA replication.
-
Transcription-associated mutation of lasR in Pseudomonas aeruginosa.
-
Transcription-dependent mobilization of nucleosomes at accessible TCR gene segments in vivo.
-
Transcriptional Regulation of SDHa flavoprotein by nuclear respiratory factor-1 prevents pseudo-hypoxia in aerobic cardiac cells.
-
Transcriptional activation of p21(waf1/cip1) by alkylphospholipids: role of the mitogen-activated protein kinase pathway in the transactivation of the human p21(waf1/cip1) promoter by Sp1.
-
Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation.
-
Transcriptional pausing in a region important for plasmid NR1 replication control.
-
Transcriptional regulation and the evolution of development.
-
Transcriptional regulation of N-acetylglutamate synthase.
-
Transcriptional regulation of Src homology 2 domain-containing leukocyte phosphoprotein of 76 kDa: dissection of key promoter elements.
-
Transcriptional regulation of chitin synthases by calcineurin controls paradoxical growth of Aspergillus fumigatus in response to caspofungin.
-
Transcriptional regulation of survivin by c-Myc in BCR/ABL-transformed cells: implications in anti-leukaemic strategy.
-
Transcriptional regulation of the cholesteryl ester transfer protein gene by the orphan nuclear hormone receptor apolipoprotein AI regulatory protein-1.
-
Transcriptional regulation of the mouse presenilin-1 gene.
-
Transcriptional regulation of the mouse uncoupling protein-2 gene. Double E-box motif is required for peroxisome proliferator-activated receptor-gamma-dependent activation.
-
Transcriptional regulation of the tyrosine hydroxylase gene by glucocorticoid and cyclic AMP.
-
Transcriptional regulatory functions of heterogeneous nuclear ribonucleoprotein-U and -A/B in endotoxin-mediated macrophage expression of osteopontin.
-
Transcriptome-Wide Identification of 2'-O-Methylation Sites with RibOxi-Seq.
-
Transduction of human melanoma cells with the gamma interferon gene enhances cellular immunity.
-
Transfer of HIV-1-specific cytotoxic T lymphocytes to an AIDS patient leads to selection for mutant HIV variants and subsequent disease progression.
-
Transfer of photosynthesis genes to and from Prochlorococcus viruses.
-
Transformation of Saccharomyces cerevisiae with nonhomologous DNA: illegitimate integration of transforming DNA into yeast chromosomes and in vivo ligation of transforming DNA to mitochondrial DNA sequences.
-
Transforming growth factor beta 1 can induce CIP1/WAF1 expression independent of the p53 pathway in ovarian cancer cells.
-
Transforming growth factor beta activates the promoter of cyclin-dependent kinase inhibitor p15INK4B through an Sp1 consensus site.
-
Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism.
-
Transforming growth factor beta-mediated transcriptional repression of c-myc is dependent on direct binding of Smad3 to a novel repressive Smad binding element.
-
Transforming single DNA molecules into fluorescent magnetic particles for detection and enumeration of genetic variations.
-
Transgene expression in zebrafish: A comparison of retroviral-vector and DNA-injection approaches.
-
Transgene induced co-suppression during vegetative growth in Cryptococcus neoformans.
-
Transgenic indicator mice for studying activated retinoic acid receptors during development.
-
Transgenic mice expressing a constitutively active retinoic acid receptor in the lens exhibit ocular defects.
-
Transgenic plants expressing potato virus X ORF2 protein (p24) are resistant to tobacco mosaic virus and Ob tobamoviruses.
-
Transglutaminase 2 protects against ischemic insult, interacts with HIF1beta, and attenuates HIF1 signaling.
-
Transient Hoogsteen base pairs in canonical duplex DNA.
-
Transient laminin beta 1a Induction Defines the Wound Epidermis during Zebrafish Fin Regeneration.
-
Translation by the adenovirus tripartite leader: elements which determine independence from cap-binding protein complex.
-
Translational inhibition of messenger RNA of the human pi class glutathione S-transferase by antisense oligodeoxyribonucleotides.
-
Transport of phosphorothioate oligonucleotides in kidney: implications for molecular therapy.
-
Transposon Tn5: specific sequence recognition and conservative transposition.
-
Tree ferns: monophyletic groups and their relationships as revealed by four protein-coding plastid loci
-
Triplet repeats form secondary structures that escape DNA repair in yeast.
-
Tumor necrosis factor-alpha induces c-jun during the regenerative response to liver injury.
-
Tumor suppressor Smad4 is a transforming growth factor beta-inducible DNA binding protein.
-
Two amino acid residues determine 2-APB sensitivity of the ion channels TRPV3 and TRPV4.
-
Two distinct forms of soluble MHC class I molecules synthesized by different mechanisms in normal rat cells in vitro.
-
Two distinct genes encode small isoproteolipids affecting plasma membrane H(+)-ATPase activity of Saccharomyces cerevisiae.
-
Two distinct mechanisms of Topoisomerase 1-dependent mutagenesis in yeast.
-
Two farnesoid X receptor alpha isoforms in Japanese medaka (Oryzias latipes) are differentially activated in vitro
-
Two mouse early embryonic beta-globin gene sequences. Evolution of the nonadult beta-globins.
-
Two mutational hotspots in the interleukin-2 receptor gamma chain gene causing human X-linked severe combined immunodeficiency.
-
Two new polymorphisms but no mutations of the KIT gene in patients with myelodysplasia at positions corresponding to human FMS and murine W locus mutational hot spots.
-
Two novel sodium channel mutations associated with resistance to indoxacarb and metaflumizone in the diamondback moth, Plutella xylostella.
-
Two proteins of the Dictyostelium spore coat bind to cellulose in vitro.
-
Two restriction-like enzymes from Xanthomonas malvacearum.
-
Two tRNA gene clusters associated with rRNA operons rrnD and rrnE in Bacillus subtilis.
-
Two types of recombination hotspots in bacteriophage T4: one requires DNA damage and a replication origin and the other does not.
-
Two-dimensional gel analysis of rolling circle replication in the presence and absence of bacteriophage T4 primase.
-
Tyloxapol inhibits NF-kappa B and cytokine release, scavenges HOCI, and reduces viscosity of cystic fibrosis sputum.
-
Type 1 neurofibromatosis gene: identification of a large transcript disrupted in three NF1 patients.
-
Type I and type II keratins have evolved from lower eukaryotes to form the epidermal intermediate filaments in mammalian skin.
-
Type I elements mediate replication fork pausing at conserved upstream sites in the Tetrahymena thermophila ribosomal DNA minichromosome.
-
Tyrosine phosphorylation of the human glutathione S-transferase P1 by epidermal growth factor receptor.
-
U1-snRNP-A protein selects a ten nucleotide consensus sequence from a degenerate RNA pool presented in various structural contexts.
-
UACUAAC is the preferred branch site for mammalian mRNA splicing.
-
UV absorption complicates PCR decontamination.
-
Ultraconserved regions encoding ncRNAs are altered in human leukemias and carcinomas.
-
Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia.
-
Understanding the characteristics of nonspecific binding of drug-like compounds to canonical stem-loop RNAs and their implications for functional cellular assays.
-
Unique oligonucleotide primers in PCR for identification of Cryptococcus neoformans.
-
Unprecedented loss of ammonia assimilation capability in a urease-encoding bacterial mutualist.
-
Unselected mutations in the human immunodeficiency virus type 1 genome are mostly nonsynonymous and often deleterious.
-
Unusual DNA sequences associated with the ends of yeast chromosomes.
-
Unusual RNA splicing generates a secreted form of HLA-A2 in a mutagenized B lymphoblastoid cell line.
-
Unveiling Inherent Degeneracies in Determining Population-Weighted Ensembles of Interdomain Orientational Distributions Using NMR Residual Dipolar Couplings: Application to RNA Helix Junction Helix Motifs.
-
Upstream stimulatory factors are mediators of Ca2+-responsive transcription in neurons.
-
Use of RNA polymerase II to transcribe artificial microRNAs.
-
Use of dominant-negative HrpA mutants to dissect Hrp pilus assembly and type III secretion in Pseudomonas syringae pv. tomato.
-
Use of retrovirus expression of interfering RNA to determine the contribution of activated K-Ras and ras effector expression to human tumor cell growth.
-
Use of site-directed mutagenesis to enhance the epitope-shielding effect of covalent modification of proteins with polyethylene glycol.
-
Using cauliflower to find conserved non-coding regions in Arabidopsis.
-
Using comparative genomic data to test for fast-X evolution.
-
Using secondary structure to identify ribosomal numts: cautionary examples from the human genome.
-
Utilization of a mammalian cell-based RNA binding assay to characterize the RNA binding properties of picornavirus 3C proteinases.
-
Utilization of a soluble integrin-alkaline phosphatase chimera to characterize integrin alpha 8 beta 1 receptor interactions with tenascin: murine alpha 8 beta 1 binds to the RGD site in tenascin-C fragments, but not to native tenascin-C.
-
UvsW protein regulates bacteriophage T4 origin-dependent replication by unwinding R-loops.
-
V region gene analysis of anti-Sm hybridomas from MRL/Mp-lpr/lpr mice.
-
V(D)J recombinase-mediated processing of coding junctions at cryptic recombination signal sequences in peripheral T cells during human development.
-
VIAF, a conserved inhibitor of apoptosis (IAP)-interacting factor that modulates caspase activation.
-
Vaccination with the immediate-early protein ICP47 of herpes simplex virus-type 1 (HSV-1) induces virus-specific lymphoproliferation, but fails to protect against lethal challenge.
-
Vaccine protection by a triple deletion mutant of simian immunodeficiency virus.
-
Vaccine-induced protection of chimpanzees against infection by a heterologous human immunodeficiency virus type 1.
-
Vaccinia virus directs the synthesis of early mRNAs containing 5' poly(A) sequences.
-
Variability on the dot chromosome in the Drosophila simulans clade.
-
Variable helix elongation as a tool to modulate RNA alignment and motional couplings.
-
Variable levels of normal RNA in different fetal organs carrying a cystic fibrosis transmembrane conductance regulator splicing mutation.
-
Variable region sequence analysis of anti-DNA antibodies: evidence for a family of closely related germ-line VH genes encoding lupus autoantibodies.
-
Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease.
-
Variant genotypes of CDKN1A and CDKN1B are associated with an increased risk of breast cancer in Chinese women.
-
Variants in melanocortin 1 receptor gene contribute to risk of melanoma--a direct sequencing analysis in a Texas population.
-
Variation in efficiency of DNA mismatch repair at different sites in the yeast genome.
-
Variations in the heme oxygenase-1 microsatellite polymorphism are associated with plasma CD14 and viral load in HIV-infected African-Americans.
-
Ventricular expression of a MLC-2v-ras fusion gene induces cardiac hypertrophy and selective diastolic dysfunction in transgenic mice.
-
Verification of a new gene on Saccharomyces cerevisiae chromosome III.
-
Vesicular stomatitis virus defective interfering particle containing a muted internal leader RNA gene.
-
Vgr-1, a mammalian gene related to Xenopus Vg-1, is a member of the transforming growth factor beta gene superfamily.
-
Vibratory loading decreases extracellular matrix and matrix metalloproteinase gene expression in rabbit annulus cells.
-
Viral and cellular microRNAs as determinants of viral pathogenesis and immunity.
-
Viral cell death inhibitor MC159 enhances innate immunity against vaccinia virus infection.
-
Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines.
-
Viral sequences determining the oncogenicity of avian leukosis viruses.
-
Virulence genes of poxviruses and reoviruses.
-
Visual cortex is rescued from the effects of dark rearing by overexpression of BDNF.
-
Visualizing RNA Conformational Changes via Pattern Recognition of RNA by Small Molecules.
-
Visualizing the formation of an RNA folding intermediate through a fast highly modular secondary structure switch.
-
Visualizing transient Watson-Crick-like mispairs in DNA and RNA duplexes.
-
Visualizing transient low-populated structures of RNA.
-
Vitamin D receptor interaction with specific DNA requires a nuclear protein and 1,25-dihydroxyvitamin D3.
-
Vitamin D receptors repress basal transcription and exert dominant negative activity on triiodothyronine-mediated transcriptional activity.
-
Vitamin K-dependent protein S in Leydig cells of human testis.
-
WT1 and DAX-1 inhibit aromatase P450 expression in human endometrial and endometriotic stromal cells.
-
WT1 and DAX-1 regulate SF-1-mediated human P450arom gene expression in gonadal cells.
-
WT1 and Sox11 regulate synergistically the promoter of the Wnt4 gene that encodes a critical signal for nephrogenesis.
-
Who owns the genome?
-
Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways.
-
Whole-genome analyses resolve early branches in the tree of life of modern birds.
-
Whole-genome fingerprint of the DNA methylome during human B cell differentiation.
-
Why sequence all eukaryotes?
-
Wide variation in the multiplicity of HIV-1 infection among injection drug users.
-
Widespread occurrence of spliceosomal introns in the rDNA genes of ascomycetes.
-
Widespread transient Hoogsteen base pairs in canonical duplex DNA with variable energetics.
-
Wild Mandrillus sphinx are carriers of two types of lentivirus.
-
Wilms' tumor suppressor gene expression in rat and human mesothelioma.
-
Working at the interface of phylogenetics and population genetics: a biogeographical analysis of Triaenops spp. (Chiroptera: Hipposideridae).
-
XPA polymorphism associated with reduced lung cancer risk and a modulating effect on nucleotide excision repair capacity.
-
Xenobiotic induction of quinone oxidoreductase activity in lens epithelial cells.
-
Yeast RSP5 and its human homolog hRPF1 potentiate hormone-dependent activation of transcription by human progesterone and glucocorticoid receptors.
-
Yin Yang 1 contains G-quadruplex structures in its promoter and 5'-UTR and its expression is modulated by G4 resolvase 1.
-
ZEITLUPE encodes a novel clock-associated PAS protein from Arabidopsis
-
Zebrafish sparse corresponds to an orthologue of c-kit and is required for the morphogenesis of a subpopulation of melanocytes, but is not essential for hematopoiesis or primordial germ cell development.
-
Zfp36l3, a rodent X chromosome gene encoding a placenta-specific member of the Tristetraprolin family of CCCH tandem zinc finger proteins.
-
Zinc finger binding motifs do not explain recombination rate variation within or between species of Drosophila.
-
[GIPC: a new target for therapy in pancreatic adenocarcinoma?].
-
c-Myb and core-binding factor/PEBP2 display functional synergy but bind independently to adjacent sites in the T-cell receptor delta enhancer.
-
c-Myc creates an activation loop by transcriptionally repressing its own functional inhibitor, hMad4, in young fibroblasts, a loop lost in replicatively senescent fibroblasts.
-
cAMP stimulates transcription of the beta 2-adrenergic receptor gene in response to short-term agonist exposure.
-
cAMP-dependent protein kinase is necessary for increased NF-E2.DNA complex formation during erythroleukemia cell differentiation.
-
cDNA cloning and chromosomal localization of the human beta-adrenergic receptor kinase.
-
cDNA cloning and expression of rat and human protein geranylgeranyltransferase type-I.
-
cDNA cloning of an intracellular form of the human interleukin 1 receptor antagonist associated with epithelium.
-
cDNA cloning of the type 1 neurofibromatosis gene: complete sequence of the NF1 gene product.
-
cDNA for the human beta 2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factor.
-
cDNA sequence and genomic structure of EV12B, a gene lying within an intron of the neurofibromatosis type 1 gene.
-
cDNA sequencing confirms HTLV-I expression in adult T-cell leukemia/lymphoma and different sequence variations in vivo and in vitro.
-
ePAD, an oocyte and early embryo-abundant peptidylarginine deiminase-like protein that localizes to egg cytoplasmic sheets.
-
hMad4, c-Myc endogenous inhibitor, induces a replicative senescence-like state when overexpressed in human fibroblasts.
-
hMutSalpha- and hMutLalpha-dependent phosphorylation of p53 in response to DNA methylator damage.
-
hrp gene-dependent induction of hin1: a plant gene activated rapidly by both harpins and the avrPto gene-mediated signal.
-
iPABP, an inducible poly(A)-binding protein detected in activated human T cells.
-
iRED analysis of TAR RNA reveals motional coupling, long-range correlations, and a dynamical hinge.
-
m(1)A and m(1)G disrupt A-RNA structure through the intrinsic instability of Hoogsteen base pairs.
-
m6A minimally impacts the structure, dynamics, and Rev ARM binding properties of HIV-1 RRE stem IIB.
-
mRNA structure determines specificity of a polyQ-driven phase separation.
-
microRNA miR-144 modulates oxidative stress tolerance and associates with anemia severity in sickle cell disease.
-
p135tyk2, an interferon-alpha-activated tyrosine kinase, is physically associated with an interferon-alpha receptor.
-
p38α mitogen-activated protein kinase depletion and repression of signal transduction to translation machinery by miR-124 and -128 in neurons.
-
p45 NF-E2 regulates expression of thromboxane synthase in megakaryocytes.
-
p53 Immunostaining guided laser capture microdissection (p53-LCM) defines the presence of p53 gene mutations in focal regions of primary prostate cancer positive for p53 protein.
-
p53 alterations in all stages of breast cancer.
-
p53 functional impairment and high p21waf1/cip1 expression in human T-cell lymphotropic/leukemia virus type I-transformed T cells.
-
p53 status in spontaneous and dimethylnitrosamine-induced renal cell tumors from rats.
-
piggyBac as a high-capacity transgenesis and gene-therapy vector in human cells and mice.
-
rac, a novel ras-related family of proteins that are botulinum toxin substrates.
-
ras oncogene mutations in diethylnitrosamine-induced hepatic tumors in medaka (Oryzias latipes), a teleost fish.
-
von Willebrand disease in the RIIIS/J mouse is caused by a defect outside of the von Willebrand factor gene.
-
vph6 mutants of Saccharomyces cerevisiae require calcineurin for growth and are defective in vacuolar H(+)-ATPase assembly.
-
Keywords of People
-
-
Bennett, Vann,
George Barth Geller Distinguished Professor of Molecular Biology,
Duke Cancer Institute
-
Berchuck, Andrew,
James M. Ingram Distinguished Professor of Gynecologic Oncology,
Obstetrics and Gynecology, Gynecologic Oncology
-
Erickson, Harold Paul,
James B. Duke Distinguished Professor Emeritus,
Cell Biology
-
Ferrari, Guido,
Professor in Surgery,
Molecular Genetics and Microbiology
-
Ferreira, Paulo Alexandre,
Associate Professor in Ophthalmology,
Pathology
-
Hartemink, Alexander J.,
Professor in the Department of Computer Science,
Biology
-
Krangel, Michael S.,
George Barth Geller Distinguished Professor of Immunology,
Immunology
-
Linardic, Corinne Mary,
Associate Professor of Pediatrics,
Cell Biology
-
Luftig, Micah Alan,
Associate Professor of Molecular Genetics and Microbiology,
Cell Biology
-
Moorman, Patricia Gripka,
Professor Emeritus in Family Medicine and Community Health,
Duke Cancer Institute
-
Schultz, Thomas F.,
Assistant Professor of the Practice of Marine Molecular Conservation,
Marine Science and Conservation
-
Soderling, Scott Haydn,
George Barth Geller Distinguished Professor of Molecular Biology,
Cell Biology
-
Sullivan, Daniel Carl,
Professor Emeritus of Radiology,
Radiology
-
Wray, Gregory Allan,
Professor of Biology,
Evolutionary Anthropology