beta-Galactosidase
-
Subject Areas on Research
- 2.2 Å resolution cryo-EM structure of β-galactosidase in complex with a cell-permeant inhibitor.
- 5' exon replacement and repair by spliceosome-mediated RNA trans-splicing.
- A cAMP response element in the beta 2-adrenergic receptor gene confers transcriptional autoregulation by cAMP.
- A calorimetric and equilibrium investigation of the hydrolysis of lactose.
- A new helper phospholipid for gene delivery.
- A pressure-mediated nonviral method for efficient arterial gene and oligonucleotide transfer.
- AMH induces mesonephric cell migration in XX gonads.
- Activation of MEF2 by muscle activity is mediated through a calcineurin-dependent pathway.
- Adenoviral-mediated gene transfer induces sustained pericardial VEGF expression in dogs: effect on myocardial angiogenesis.
- Adenovirus-mediated gene transfer into rat cardiac allografts. Comparison of direct injection and perfusion.
- Adenovirus-mediated gene transfer to nonparenchymal cells in normal and injured liver.
- Adenovirus-mediated genetic manipulation of the myocardial beta-adrenergic signaling system in transplanted hearts.
- Analysis of muscle creatine kinase regulatory elements in recombinant adenoviral vectors.
- Antigenicity of a recombinant Ro (SS-A) fusion protein.
- Appearance of protease activities coincides with p10 and polyhedrin-driven protein production in the baculovirus expression system: effects on yield.
- Aromatic hydrocarbon receptor polymorphism: development of new methods to correlate genotype with phenotype.
- Atomic Resolution Cryo-EM Structure of β-Galactosidase.
- Bleomycin induces the hsp 70 heat shock promoter in cultured cells.
- CBX4 Regulates Replicative Senescence of WI-38 Fibroblasts.
- Carbohydrate on human factor VIII/von Willebrand factor. Impairment of function by removal of specific galactose residues.
- Cardiac gene delivery with cardiopulmonary bypass.
- Cardiac-specific LIM protein FHL2 modifies the hypertrophic response to beta-adrenergic stimulation.
- Catheter-based intracoronary myocardial adenoviral gene delivery: importance of intraluminal seal and infusion flow rate.
- Catheter-mediated subselective intracoronary gene delivery to the rabbit heart: introduction of a novel method.
- Cell-mediated cytotoxicity of murine cytomegalovirus-infected target cells allows for release of residual infectious virus.
- Cellular senescence in the glaucomatous outflow pathway.
- Charge-reversal amphiphiles for gene delivery.
- Classification and genetic characterization of pattern-forming Bacilli.
- Cloning and characterization of the major promoter of the human protein kinase C beta gene. Regulation by phorbol esters.
- Cytosine deamination in mismatched base pairs.
- Delivery of primary autologous skeletal myoblasts into rabbit heart by coronary infusion: a potential approach to myocardial repair.
- Desert Hedgehog/Patched 1 signaling specifies fetal Leydig cell fate in testis organogenesis.
- Development of a high-efficiency method for gene marking of Dunning prostate cancer cell lines with the enzyme beta-galactosidase.
- Differential regulation of dopamine D1A receptor responsiveness by various G protein-coupled receptor kinases.
- Distinct mesodermal signals, including BMPs from the septum transversum mesenchyme, are required in combination for hepatogenesis from the endoderm.
- Does thalidomide affect IL-2 response and production?
- Effect of NF-kappa B inhibition on TNF-alpha-induced apoptosis in human RPE cells.
- Effect of a dominant negative ras on myocardial hypertrophy by using adenoviral-mediated gene transfer.
- Effect of isopropyl-beta-D-thiogalactopyranosid induction of the lac operon on the specificity of spontaneous and doxorubicin-induced mutations in Escherichia coli.
- Effect of mutant IkappaB on cytokine-induced activation of NF-kappaB in cultured human RPE cells.
- Efficacy of multiple administrations of a recombinant adenovirus expressing wild-type p53 in an immune-competent mouse tumor model.
- Efficient adenoviral gene transfer to early venous bypass grafts: comparison with native vessels.
- Efficient in vivo gene transfer into the heart in the rat myocardial infarction model using the HVJ (Hemagglutinating Virus of Japan)--liposome method.
- Endothelial Bmp4 is induced during arterial remodeling: effects on smooth muscle cell migration and proliferation.
- Enhanced growth of small bowel in transgenic mice overexpressing bovine growth hormone.
- Enhanced vasorelaxation by overexpression of beta 2-adrenergic receptors in large arteries.
- Eradication of solid human breast tumors in nude mice with an intravenously injected light-emitting oncolytic vaccinia virus.
- Estrogen levels in childhood determined by an ultrasensitive recombinant cell bioassay.
- Ex vivo adenovirus-mediated gene transfer to the adult rat heart.
- Experimental and numerical studies of adenovirus delivery to outflow tissues of perfused human anterior segments.
- Expression analysis of the matrix GLA protein and VE-cadherin gene promoters in the outflow pathway.
- Expression of a peptide inhibitor of protein phosphatase 1 increases phosphorylation and activity of CREB in NIH 3T3 fibroblasts.
- Expression of polyoma early gene products in E. coli.
- Expression of the 71 kDa dystrophin isoform (Dp71) evaluated by gene targeting.
- Fusigenic liposome-mediated DNA transfer into cardiac myocytes.
- GRP94-associated enzymatic activities. Resolution by chromatographic fractionation.
- Gene transfer of endothelial nitric oxide synthase improves relaxation of carotid arteries from diabetic rabbits.
- Glomerular beta-galactosidase expression following transduction with microsphere-adenoviral complexes.
- Growth factors regulate beta-catenin-mediated TCF-dependent transcriptional activation in fibroblasts during the proliferative phase of wound healing.
- High level expression of biologically active estrogen receptor in Saccharomyces cerevisiae.
- High-efficiency, long-term cardiac expression of foreign genes in living mouse embryos and neonates.
- Hmo1p, a high mobility group 1/2 homolog, genetically and physically interacts with the yeast FKBP12 prolyl isomerase.
- Hyaluronic acid and fibrin hydrogels with concentrated DNA/PEI polyplexes for local gene delivery
- Identification of a negative regulatory function for steroid receptors.
- Identifying a transcription factor interaction site on RNA polymerase II.
- In vivo cytotoxic T lymphocyte induction with soluble proteins administered in liposomes.
- Inhibition of Bmp signaling affects growth and differentiation in the anagen hair follicle.
- Interactions of estrogen- and thyroid hormone receptors on a progesterone receptor estrogen response element (ERE) sequence: a comparison with the vitellogenin A2 consensus ERE.
- Intracoronary adenovirus-mediated delivery and overexpression of the beta(2)-adrenergic receptor in the heart : prospects for molecular ventricular assistance.
- Isolation and transplantation of autologous circulating endothelial cells into denuded vessels and prosthetic grafts: implications for cell-based vascular therapy.
- Isolation of retinal proteins that interact with retinitis pigmentosa GTPase regulator by interaction trap screen in yeast.
- Kinetics of bisulfite-induced cytosine deamination in single-stranded DNA.
- LexA protein of Escherichia coli represses expression of the Tn5 transposase gene.
- Local sources of retinoic acid coincide with retinoid-mediated transgene activity during embryonic development.
- Lysosomal basification and decreased autophagic flux in oxidatively stressed trabecular meshwork cells: implications for glaucoma pathogenesis.
- Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts.
- Naked DNA delivered intraportally expresses efficiently in hepatocytes.
- Nerve activity-dependent modulation of calcineurin signaling in adult fast and slow skeletal muscle fibers.
- Nonfunctional Missense Mutants in Two Well Characterized Cytosolic Enzymes Reveal Important Information About Protein Structure and Function.
- Odorant receptors govern the formation of a precise topographic map.
- Oxidative stress impact on barrier function of porcine angular aqueous plexus cell monolayers.
- PEDF Deletion Induces Senescence and Defects in Phagocytosis in the RPE.
- Parent-specific expression of a human keratin 18/beta-galactosidase fusion gene in transgenic mice.
- Peptide elongation factor eEF1A-2/S1 expression in cultured differentiated myotubes and its protective effect against caspase-3-mediated apoptosis.
- Peripheral mobilization of recipient bone marrow-derived endothelial progenitor cells enhances pancreatic islet revascularization and engraftment after intraportal transplantation.
- Persistence and survival of autologous muscle derived cells versus bovine collagen as potential treatment of stress urinary incontinence.
- Polyspecific binding of Escherichia coli beta-galactosidase by murine antibodies to DNA.
- Potential for germ line transmission after intramyocardial gene delivery by adeno-associated virus.
- Production of recombinant adeno-associated viral vectors and use for in vitro and in vivo administration.
- Quantitative immunoassay of anti-La antibodies using purified recombinant La antigen.
- Robust adenoviral and adeno-associated viral gene transfer to the in vivo murine heart: application to study of phospholamban physiology.
- Role for hedgehog signaling in hepatic stellate cell activation and viability.
- SOS induction as an in vivo assay of enzyme-DNA interactions.
- Simultaneous proteomic profiling of four different growth states of human fibroblasts, using amine-reactive isobaric tagging reagents and tandem mass spectrometry.
- Sparing effect of leptin on liver glycogen stores in rats during the fed-to-fasted transition.
- Specific targeting of gene expression to a subset of human trabecular meshwork cells using the chitinase 3-like 1 promoter.
- Structure of β-galactosidase at 3.2-Å resolution obtained by cryo-electron microscopy.
- Study of Cryptococcus neoformans actin gene regulation with a beta-galactosidase-actin fusion.
- Systemic production of human granulocyte colony-stimulating factor in nonhuman primates by transplantation of genetically modified myoblasts.
- Targeted DNA recombination in vivo using an adenovirus carrying the cre recombinase gene.
- Targeted gene transfer to Schlemm's canal by retroperfusion.
- Tethering ribozymes to a retroviral packaging signal for destruction of viral RNA.
- The Drosophila hindgut lacks constitutively active adult stem cells but proliferates in response to tissue damage.
- The SV40 core sequence functions as a repressor element in yeast.
- The end of the beginning. Gene transfer into the vessel wall.
- The epsilon subunit of DNA polymerase III Is involved in the nalidixic acid-induced SOS response in Escherichia coli.
- The human plasminogen activator inhibitor type I gene promoter targets to kidney.
- The role of the forkhead transcription factor, Foxc1, in the development of the mouse lacrimal gland.
- Transgenic indicator mice for studying activated retinoic acid receptors during development.
- Transmyocardial laser revascularization limits in vivo adenoviral-mediated gene transfer in porcine myocardium.
- Transplantation of embryonic stem cells into the infarcted mouse heart: formation of multiple cell types.
- Transplantation of multipotent progenitors from the adult olfactory epithelium.
- Transrectal gene therapy of the prostate in the canine model.
- Tumor-dendritic cell fusion as a basis for cancer immunotherapy.
- Vascular tissues are a primary source of BMP2 expression during bone formation induced by distraction osteogenesis.
- Vascular-mesenchymal cross-talk through Vegf and Pdgf drives organ patterning.
- Viral sequences enable efficient and tissue-specific expression of transgenes in Xenopus.
- beta-cell function in normal rats made chronically hyperleptinemic by adenovirus-leptin gene therapy.
- bullwinkle is required for epithelial morphogenesis during Drosophila oogenesis.
-
Keywords of People
- Hogan, Brigid L. M., Research Professor of Cell Biology, Cell Biology
- Milano, Carmelo Alessio, Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery, Surgery, Cardiovascular and Thoracic Surgery
- Stinnett, Sandra Sue, Associate Professor of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics