Bile Acids and Salts

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  Subject Areas on Research

  • A Fibrosis-Independent Hepatic Transcriptomic Signature Identifies Drivers of Disease Progression in Primary Sclerosing Cholangitis. 
  • A physicochemical study of fat absorption in rats. Limitation of methods in vitro. 
  • A structurally optimized FXR agonist, MET409, reduced liver fat content over 12 weeks in patients with non-alcoholic steatohepatitis. 
  • A targeted analysis reveals relevant shifts in the methylation and transcription of genes responsible for bile acid homeostasis and drug metabolism in non-alcoholic fatty liver disease. 
  • Adverse reactions of Achilles tendon xanthomas in three hypercholesterolemic patients after treatment intensification with niacin and bile acid sequestrants. 
  • Altered bile acid profile associates with cognitive impairment in Alzheimer's disease-An emerging role for gut microbiome. 
  • Altered bile acid profile in mild cognitive impairment and Alzheimer's disease: Relationship to neuroimaging and CSF biomarkers. 
  • Applicability of the reported prevalence of bile salt malabsorption in irritable bowel. 
  • Assessment and significance of bacterial overgrowth in the small bowel. 
  • Bile acid aspiration associated with lung chemical profile linked to other biomarkers of injury after lung transplantation. 
  • Bile acid synthesis, modulation, and dementia: A metabolomic, transcriptomic, and pharmacoepidemiologic study. 
  • Bile acid transport in the anhepatic rat. 
  • Bile acids in xenogeneic ex-vivo liver perfusion: function of xenoperfused livers and compatibility with human bile salts and porcine livers. 
  • Bile acids targeted metabolomics and medication classification data in the ADNI1 and ADNIGO/2 cohorts. 
  • Bile compositional changes and cholesterol stone formation following orthotopic liver transplantation. 
  • Bile flow--an index of ischemic injury. 
  • Bile salts stimulate glycoprotein release by guinea pig gallbladder in vitro. 
  • Biliary response to glucagon and insulin following hepatic transplantation in humans. 
  • Biliary response to glucagon in humans. 
  • Biliary secretion of extracorporeal porcine livers with single and dual vessel perfusion. 
  • Bronchoalveolar bile acid and inflammatory markers to identify high-risk lung transplant recipients with reflux and microaspiration. 
  • Calcium binding by monosulfate esters of taurochenodeoxycholate. 
  • Cholesterol homeotasis in rats fed a purified diet. 
  • Cholestyramine feeding lowers number of colonic apoptotic cells in rat. 
  • Clinical and physiological abnormalities in hepatic function. 
  • Combining biomarkers in irritable bowel syndrome: a forward step toward making a positive diagnosis and directing therapy? 
  • Demonstration and characterization of the hemoconcentrating effect of ascitic fluid that accumulates during hemorrhagic pancreatitis. 
  • Diet rapidly and reproducibly alters the human gut microbiome. 
  • Effect of NGM282, an FGF19 analogue, in primary sclerosing cholangitis: A multicenter, randomized, double-blind, placebo-controlled phase II trial. 
  • Effect of cyclosporine on bile secretion in rats. 
  • Effects of bombesin on fasting bile formation. 
  • Effects of dibutyryl cyclic AMP and theophylline on biliary cholesterol secretion. 
  • Effects of serotonin on canine bile formation. 
  • Efficiency of various bile salt preparations for stimulation of Clostridium difficile spore germination. 
  • Enteric microbiome metabolites correlate with response to simvastatin treatment. 
  • Expert insights: The potential role of the gut microbiome-bile acid-brain axis in the development and progression of Alzheimer's disease and hepatic encephalopathy. 
  • Farnesoid-X Receptor (FXR) as a Promising Pharmaceutical Target in Atherosclerosis. 
  • Fat digestion in patients with bile acid malabsorption but minimal steatorrhea. 
  • Fecal steroids in diarrhea. II. Travellers' diarrhea. 
  • Fxr signaling and microbial metabolism of bile salts in the zebrafish intestine. 
  • Gallbladder Na+/H+ exchange activity is up-regulated prior to cholesterol crystal formation. 
  • Gallbladder density and iodine concentration in humans during oral cholecystography. A comparison of iopanoic acid and iopronic acid. 
  • Glucagon or insulin suppressed biliary lipid excretion in dog and man. 
  • Glucose and lipid effects of the ileal apical sodium-dependent bile acid transporter inhibitor GSK2330672: double-blind randomized trials with type 2 diabetes subjects taking metformin. 
  • High Prevalence of Idiopathic Bile Acid Diarrhea Among Patients With Diarrhea-Predominant Irritable Bowel Syndrome Based on Rome III Criteria. 
  • Inhibition of basal and meal-stimulated choleresis by somatostatin. 
  • Inhibition of bile flow by intravenous arginine hydrochloride. 
  • Insulin or glucagon choleresis in the isolated perfused guinea pig liver. 
  • Intestinal Sulfation Is Essential to Protect Against Colitis and Colonic Carcinogenesis. 
  • Intestinal adaptation after ileal interposition surgery increases bile acid recycling and protects against obesity-related comorbidities. 
  • Isolation of polyribosomes and characteristics of an amino acid-incorporation system from the liver of a primate (Papio papio). 
  • Letter: bile acid diarrhoea is not a rare cause of diarrhoea in secondary care. 
  • Lipids and bariatric procedures part 1 of 2: Scientific statement from the National Lipid Association, American Society for Metabolic and Bariatric Surgery, and Obesity Medicine Association: EXECUTIVE SUMMARY. 
  • Lipids and bariatric procedures part 1 of 2: Scientific statement from the National Lipid Association, American Society for Metabolic and Bariatric Surgery, and Obesity Medicine Association: FULL REPORT. 
  • Management of dyslipidemia in children and adolescents with systemic lupus erythematosus. 
  • Metabolic Network Analysis Reveals Altered Bile Acid Synthesis and Metabolism in Alzheimer's Disease. 
  • Metabolomic Signature as a Predictor of Liver Disease Events in Patients With HIV/HCV Coinfection. 
  • Mig-6 plays a critical role in the regulation of cholesterol homeostasis and bile acid synthesis. 
  • Origins of fecal neutral steroids in rats. 
  • Pharmacometabolomics of statin response. 
  • Prevalence of, and predictors of, bile acid diarrhea in outpatients with chronic diarrhea: A follow-up study. 
  • Prevalence of, and predictors of, bile acid malabsorption in outpatients with chronic diarrhea. 
  • Proton magnetic resonance studies of the aggregation of taurine-conjugated bile salts. 
  • Recombinant acyl-CoA:cholesterol acyltransferase-1 (ACAT-1) purified to essential homogeneity utilizes cholesterol in mixed micelles or in vesicles in a highly cooperative manner. 
  • Reflux of bile acids: an innate problem of lung transplantation. 
  • Regulation of biliary protein secretion in dogs. 
  • Regulation of biliary secretion following liver transplantation. 
  • Regulation of hepatic biliary secretion. 
  • Regulation of plasma cholecystokinin levels by bile and bile acids in the rat. 
  • Remodelling of the Vibrio cholerae membrane by incorporation of exogenous fatty acids from host and aquatic environments. 
  • Screening for bile acid diarrhoea in suspected irritable bowel syndrome. 
  • Selective biliary secretion of basal and glucagon-inhibited neutral sterol after triparanol administration. 
  • Serum Bile Acid, Vitamin E, and Serotonin Metabolites Are Associated With Future Liver-Related Events in Nonalcoholic Fatty Liver Disease. 
  • Serum metabolomic biomarkers of perceptual speed in cognitively normal and mildly impaired subjects with fasting state stratification. 
  • Somatostatin-induced cholestasis can be independent of portal blood flow. 
  • Systematic review with meta-analysis: the prevalence of bile acid malabsorption in the irritable bowel syndrome with diarrhoea. 
  • The Gut Microbiota Modulates Energy Metabolism in the Hibernating Brown Bear Ursus arctos. 
  • The absorption of oleic acid from emulsion and micellar solution. 
  • The absorption of tristearin and stearic acid and tripalmitin and palmitic acid. Studies on the rate-limiting steps in rats. 
  • The effect of abdominal evisceration or adrenalectomy on insulin choleresis. 
  • The effects of liver denervation on the regulation of hepatic biliary secretion. 
  • The sources of rat biliary cholesterol and bile acid. 
  • Two farnesoid X receptor alpha isoforms in Japanese medaka (Oryzias latipes) are differentially activated in vitro