Biopolymers

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  Subject Areas on Research

  • A highly parallel method for synthesizing DNA repeats enables the discovery of 'smart' protein polymers. 
  • A surprising twist. 
  • A thermally responsive biopolymer for intra-articular drug delivery. 
  • Amyloid-beta1-42 reduces neuronal excitability in mouse dentate gyrus. 
  • An injectable and in situ-gelling biopolymer for sustained drug release following perineural administration. 
  • Applications and societal benefits of plastics. 
  • Bayesian k -space-time reconstruction of MR spectroscopic imaging for enhanced resolution. 
  • Brachytherapy via a depot of biopolymer-bound 131I synergizes with nanoparticle paclitaxel in therapy-resistant pancreatic tumours. 
  • Cool as a cucumber. 
  • Cutting edge: trimolecular interaction of TCR with MHC class II and bacterial superantigen shows a similar affinity to MHC:peptide ligands. 
  • Discovery of Welcome Biopolymers in Surface Water: Improvements in Drinking Water Production. 
  • Downhill kinetics of biomolecular interface binding: globally connected scenario. 
  • Efficient global biopolymer sampling with end-transfer configurational bias Monte Carlo. 
  • Elastin-Like Polypeptides for Biomedical Applications. 
  • Elastin-like polypeptides: biomedical applications of tunable biopolymers. 
  • Evaluating the uncertainty in exchange parameters determined from off-resonance R1ρ relaxation dispersion for systems in fast exchange. 
  • Fluorescence photobleaching with spatial Fourier analysis: measurement of diffusion in light-scattering media. 
  • Founder's Award, Society for Biomaterials. Sixth World Biomaterials Congress 2000, Kamuela, HI,May 15-20, 2000. Really smart bioconjugates of smart polymers and receptor proteins. 
  • Fusion of fibroblast growth factor 21 to a thermally responsive biopolymer forms an injectable depot with sustained anti-diabetic action. 
  • Gamma-tubulin nucleation: template or protofilament? 
  • Guanidine hydrochloride reactivates an ancient septin hetero-oligomer assembly pathway in budding yeast. 
  • How calcium causes microtubule depolymerization. 
  • In situ growth of a stoichiometric PEG-like conjugate at a protein's N-terminus with significantly improved pharmacokinetics. 
  • Injectable intratumoral depot of thermally responsive polypeptide-radionuclide conjugates delays tumor progression in a mouse model. 
  • Membrane insertion, glycosylation, and oligomerization of inositol trisphosphate receptors in a cell-free translation system. 
  • Micropatterning biological molecules on a polymer surface using elastomeric microwells. 
  • Microrheology of hyaluronan solutions: implications for the endothelial glycocalyx. 
  • Microtubule treadmilling in vitro investigated by fluorescence speckle and confocal microscopy. 
  • Modular, well-behaved reversible polymers from DNA-based monomers. 
  • Narrow groove plasmonic nano-gratings for surface plasmon resonance sensing. 
  • Needle-Free Injection of Exosomes Derived from Human Dermal Fibroblast Spheroids Ameliorates Skin Photoaging. 
  • Optimal specificity and function for flexible biomolecular recognition. 
  • Pair-wise interactions of polymerization inhibitory contact site mutations of hemoglobin-S. 
  • Planar integrated optical methods for examining thin films and their surface adlayers. 
  • Polymerization of Ftsz, a bacterial homolog of tubulin. is assembly cooperative? 
  • Pretreatment of amphiphilic comb polymer surfaces dramatically affects protein adsorption 
  • Propagation of fluctuations in biochemical systems, II: Nonlinear chains. 
  • Purification and assembly of FtsZ. 
  • Response of blood leukocytes to thrombin receptor peptides. 
  • Septin assemblies form by diffusion-driven annealing on membranes. 
  • Structure of an HIV-1-neutralizing antibody target, the lipid-bound gp41 envelope membrane proximal region trimer. 
  • Structure of the cytochrome c oxidase dimer. Electron microscopy of two-dimensional crystals. 
  • Superfibronectin, a multimeric form of fibronectin, increases HIV infection of primary CD4+ T lymphocytes. 
  • The basic helix-loop-helix domain of the aryl hydrocarbon receptor nuclear transporter (ARNT) can oligomerize and bind E-box DNA specifically. 
  • The chemokines IL-8, monocyte chemoattractant protein-1, and I-309 are monomers at physiologically relevant concentrations. 
  • The polarity and magnitude of ambient charge influences three-dimensional neurite extension from DRGs. 
  • XMAP215 is a long thin molecule that does not increase microtubule stiffness. 
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  Keywords of People

  • Erickson, Harold Paul, James B. Duke Distinguished Professor Emeritus, Cell Biology
  • Krangel, Michael S., George Barth Geller Distinguished Professor of Immunology, Integrative Immunobiology