Bleomycin

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  Subject Areas on Research

  • 3D MRI of impaired hyperpolarized 129Xe uptake in a rat model of pulmonary fibrosis. 
  • A macrophage subpopulation recruited by CC chemokine ligand-2 clears apoptotic cells in noninfectious lung injury. 
  • A malignant lymphoma with histological features and immunophenotypic profile intermediate between EBV-positive diffuse large B-cell lymphoma and EBV-positive classical Hodgkin lymphoma in a 67-year-old female: a "gray zone" lymphoma associated with Epstein-Barr virus in the elderly. 
  • A micro-CT analysis of murine lung recruitment in bleomycin-induced lung injury. 
  • A micro-computed tomography-based method for the measurement of pulmonary compliance in healthy and bleomycin-exposed mice. 
  • A trial of outpatient chemotherapy for recurrent head and neck tumors. 
  • Adult Lung Spheroid Cells Contain Progenitor Cells and Mediate Regeneration in Rodents With Bleomycin-Induced Pulmonary Fibrosis. 
  • Advanced prostatic carcinoma: pulmonary manifestations. 
  • Airway epithelial progenitors are region specific and show differential responses to bleomycin-induced lung injury. 
  • Allogeneic marrow transplantation in the treatment of MOPP-resistant Hodgkin's disease. 
  • Alveolar macrophage apoptosis and TNF-alpha, but not p53, expression correlate with murine response to bleomycin. 
  • Ambulatory sclerotherapy for malignant pleural effusions. 
  • An expanded risk prediction model for lung cancer. 
  • Anti-fibrotic effects of different sources of MSC in bleomycin-induced lung fibrosis in C57BL6 male mice. 
  • Association between family history of cancer and mutagen sensitivity in upper aerodigestive tract cancer patients. 
  • Bleomycin induces the hsp 70 heat shock promoter in cultured cells. 
  • CALGB 50604: risk-adapted treatment of nonbulky early-stage Hodgkin lymphoma based on interim PET. 
  • CD19 regulates skin and lung fibrosis via Toll-like receptor signaling in a model of bleomycin-induced scleroderma. 
  • CD19 regulates the development of bleomycin-induced pulmonary fibrosis in a mouse model. 
  • Cancer chemotherapeutic response and intravenous hyperalimentaion. 
  • Carcinoma of an unknown primary site: a chemotherapy strategy based on histological differentiation--results of a prospective study. 
  • Cell adhesion molecules regulate fibrotic process via Th1/Th2/Th17 cell balance in a bleomycin-induced scleroderma model. 
  • Correlation of intralesional in vivo chemotherapy of line 10 hepatoma with in vitro drug sensitivity. 
  • DTIC, CCNU, bleomycin and vincristine (BOLD) in metastatic melanoma. 
  • Gemcitabine, vinorelbine, and pegylated liposomal doxorubicin (GVD), a salvage regimen in relapsed Hodgkin's lymphoma: CALGB 59804. 
  • Gene expression profiling of familial and sporadic interstitial pneumonia. 
  • Genetic susceptibility to tobacco carcinogenesis. 
  • Hodgkin lymphoma arising in patients with chronic lymphocytic leukemia: outcomes from a large multi-center collaboration. 
  • Hodgkin lymphoma treatment with ABVD in the US and the EU: neutropenia occurrence and impaired chemotherapy delivery. 
  • How important is bleomycin in the adriamycin + bleomycin + vinblastine + dacarbazine regimen? 
  • Immediate adjuvant chemotherapy versus observation with treatment at relapse in pathological stage II testicular cancer. 
  • In vitro chemotherapy testing of transitional cell carcinoma. 
  • In vitro synergism between hybrid immunotoxins and chemotherapeutic drugs: relevance to immunotherapy of prostate carcinoma. 
  • In vivo treatment sensitivity testing with positron emission tomography/computed tomography after one cycle of chemotherapy for Hodgkin lymphoma. 
  • Increased expression of the glucose-regulated gene encoding the Mr 78,000 glucose-regulated protein in chemically and radiation-transformed C3H 10T1/2 mouse embryo cells. 
  • Induction of tenascin in rat lungs undergoing bleomycin-induced pulmonary fibrosis. 
  • Inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis. 
  • Intercellular adhesion molecule-1 and L-selectin regulate bleomycin-induced lung fibrosis. 
  • Interspecies cytogenetic comparisons: studies with X-radiation and bleomycin sulfate. 
  • Long-term follow-up of survival in Hodgkin's lymphoma. 
  • Low-dose consolidation radiation therapy for early stage unfavorable Hodgkin lymphoma. 
  • Mitochondrial DNA-depleted A549 cells are resistant to bleomycin. 
  • Mitochondrial biogenesis in the pulmonary vasculature during inhalational lung injury and fibrosis. 
  • Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition. 
  • Mutagen sensitivity in upper aerodigestive tract cancer: a case-control analysis. 
  • Mutagen sensitivity to benzo(a)pyrene diol epoxide and the risk of squamous cell carcinoma of the head and neck. 
  • Negative regulation of myofibroblast differentiation by PTEN (Phosphatase and Tensin Homolog Deleted on chromosome 10). 
  • Nucleosome in patients with systemic sclerosis: possible association with immunological abnormalities via abnormal activation of T and B cells. 
  • POG 8625: a randomized trial comparing chemotherapy with chemoradiotherapy for children and adolescents with Stages I, IIA, IIIA1 Hodgkin Disease: a report from the Children's Oncology Group. 
  • Paraneoplastic limbic encephalopathy with testicular carcinoma. A reversible neurologic syndrome. 
  • Phase II evaluation of cisplatin, bleomycin, and vindesine in advanced squamous cell carcinoma of the esophagus: a Southeastern Cancer Study Group Trial. 
  • Potentiation of bleomycin lethality by anticalmodulin drugs: a role for calmodulin in DNA repair. 
  • Predicting Cardiovascular Disease Among Testicular Cancer Survivors After Modern Cisplatin-based Chemotherapy: Application of the Framingham Risk Score. 
  • Preoperative therapy for esophageal cancer: a randomized comparison of chemotherapy versus radiation therapy. 
  • Prospective analysis of DNA damage and repair markers of lung cancer risk from the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial. 
  • Pulmonary fibrosis: thinking outside of the lung. 
  • Radiation techniques for the treatment of Hodgkin's disease with combined modality therapy or radiation alone. 
  • Recruited exudative macrophages selectively produce CXCL10 after noninfectious lung injury. 
  • Regulation of lysyl oxidase mRNA in dermal fibroblasts from normal donors and patients with inherited connective tissue disorders. 
  • Safe administration of hyperbaric oxygen after bleomycin: a case series of 15 patients. 
  • Safety and Efficacy of Allogeneic Lung Spheroid Cells in a Mismatched Rat Model of Pulmonary Fibrosis. 
  • Sclerotherapy for malignant pleural effusions: a prospective randomized trial of bleomycin vs doxycycline with small-bore catheter drainage. 
  • Smad3 deficiency attenuates bleomycin-induced pulmonary fibrosis in mice. 
  • Studies of tumor metabolism--II. Mössbauer spectroscopy of 57Co-bleomycin. 
  • Susceptibility of signal transducer and activator of transcription-1-deficient mice to pulmonary fibrogenesis. 
  • Targeting Inhibitor of Apoptosis Proteins Protects from Bleomycin-Induced Lung Fibrosis. 
  • The patient experience of ABVD treatment in Hodgkin lymphoma: a retrospective cohort study of patient-reported distress. 
  • Tn5-mediated bleomycin resistance in Escherichia coli requires the expression of host genes. 
  • Treatment of recurrent and metastatic endometrial cancer with cisplatin, doxorubicin, cyclophosphamide, and megestrol acetate. 
  • Treatment of superficial carcinoma of the bladder. 
  • Unnecessary mastectomy for gynecomastia in testicular cancer patient. 
  • Vascular release of nonheme iron in perfused rabbit lungs. 
  • Vincristine, bleomycin, methotrexate, 5-fluorouracil, and prednisone in metastatic, hormonally unresponsive prostatic adenocarcinoma. 
  • β-arrestin deficiency protects against pulmonary fibrosis in mice and prevents fibroblast invasion of extracellular matrix. 
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  Keywords of People

  • Gunn, Michael Dee, Professor of Medicine, Integrative Immunobiology
  • Hogan, Brigid L. M., Research Professor of Cell Biology, Cell Biology
  • Patz Jr., Edward F., James and Alice Chen Distinguished Professor of Radiology, Pathology