Blood Coagulation Disorders

• 

  Subject Areas on Research

  • "Communication from the Scientific and Standardization Committee of the International Society on Thrombosis and Hemostasis on sepsis-induced coagulopathy in the management of sepsis": reply. 
  • "Systematic review of viscoelastic testing (TEG/ROTEM) in obstetrics and recommendation from the women's SSC of the ISTH": Response to comment from Kitchen et al. 
  • A case of reversible posterior leukoencephalopathy syndrome caused by transient hypercoagulable state induced by infection. 
  • Amitriptyline Treatment Mitigates Sepsis-Induced Tumor Necrosis Factor Expression and Coagulopathy. 
  • Anticoagulation in heart failure: current status and future direction. 
  • Anticoagulation. 
  • Antifibrinolytic Therapy and Perioperative Considerations. 
  • Antihuman factor V antibodies after use of relatively pure bovine thrombin. 
  • Association of the 98T ELAM-1 polymorphism with increased bleeding after cardiac surgery. 
  • Bad weed: synthetic cannabinoid-associated coagulopathy. 
  • Biology of Coagulation and Coagulopathy in Neurologic Surgery. 
  • Bleeding and management of coagulopathy. 
  • Bleeding disorders in adolescents. 
  • Bleeding disorders in premenopausal women: (another) public health crisis for hematology? 
  • Blood transfusion in trauma patients: unresolved questions. 
  • COVID-19-associated Coagulopathy. 
  • Clinical and laboratory evaluation of the hypercoagulable states. 
  • Clinical application of pharmacogenetics: focusing on practical issues. 
  • Coagulation Abnormalities and Clinical Complications in Children With SARS-CoV-2: A Systematic Review of 48,322 Patients. 
  • Coagulation Abnormalities in Heart Failure: Pathophysiology and Therapeutic Implications. 
  • Coagulation abnormalities in patients with hip osteonecrosis. 
  • Coagulation and inflammation in acute lung injury. 
  • Coagulation defects and altered hemodynamic responses in mice lacking receptors for thromboxane A2. 
  • Coagulation disorders and hemostasis in liver disease: pathophysiology and critical assessment of current management. 
  • Coagulation disorders and their cutaneous presentations: Diagnostic work-up and treatment. 
  • Coagulation disorders and their cutaneous presentations: Pathophysiology. 
  • Coagulation parameters in copperhead compared to other Crotalinae envenomation: secondary analysis of the F(ab')2 versus Fab antivenom trial. 
  • Coagulopathy and inflammation in neonatal heart surgery: mechanisms and strategies. 
  • Coagulopathy does not fully protect hospitalized cirrhosis patients from peripheral venous thromboembolism. 
  • Coagulopathy in COVID-19. 
  • Coagulopathy in α-galactosyl transferase knockout pulmonary xenotransplants. 
  • Coagulopathy is prevalent and associated with adverse outcomes in transfused pediatric trauma patients. 
  • Coagulopathy of Coronavirus Disease 2019. 
  • Communication from the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis on sepsis-induced coagulopathy in the management of sepsis. 
  • Comparison of F(ab')2 versus Fab antivenom for pit viper envenomation: a prospective, blinded, multicenter, randomized clinical trial. 
  • Continuous IV Crotalidae Polyvalent Immune Fab (Ovine) (FabAV) for selected North American rattlesnake bite patients. 
  • Controlled Multifactorial Coagulopathy: Effects of Dilution, Hypothermia, and Acidosis on Thrombin Generation In Vitro. 
  • Cryoprecipitate therapy. 
  • Defining trauma-induced coagulopathy with respect to future implications for patient management: Communication from the SSC of the ISTH. 
  • Development of a Metastatic Spinal Tumor Frailty Index (MSTFI) Using a Nationwide Database and Its Association with Inpatient Morbidity, Mortality, and Length of Stay After Spine Surgery. 
  • Diagnostic testing for coagulopathies in patients with ischemic stroke. 
  • Differences in bleeding phenotype and provider interventions in postmenarchal adolescents when compared to adult women with bleeding disorders and heavy menstrual bleeding. 
  • Disseminated Intravascular Coagulation: The Past, Present, and Future Considerations. 
  • Dysregulation of hemostasis by cancer. 
  • Early trauma induced coagulopathy (ETIC): prevalence across the injury spectrum. 
  • Elevated urokinase-type plasminogen activator level and bleeding in amyloidosis: case report and literature review. 
  • Evaluation of a modified procedure for Staclot LA for the confirmation of lupus anticoagulants. 
  • Evaluation of hemostasis by the Clot Signature Analyzer: a potentially valuable device for the anesthesiologist. 
  • Experimental transfusion reactions and disseminated intravascular coagulation produced by incompatible plasma in monkeys. 
  • Experimental transfusion reactions in monkeys: haemolytic, coagulant and renal effects of transfused isoimmune IgG and IgM. 
  • Failure of low molecular weight dextran to prevent clotting during continuous renal replacement therapy. 
  • Feasibility and safety of moderate hypothermia after massive hemispheric infarction. 
  • Fibrinogen and bleeding: old molecule--new ideas. 
  • Fibrinolysis vs disseminated intravascular coagulation. 
  • Fibrinolytic abnormalities in two different cutaneous manifestations of venous disease. 
  • Haemostasis: from bench to bedside. 
  • Hematologic and economic impact of aprotinin in reoperative pediatric cardiac operations. 
  • Hemorrhagic stroke in the Stroke Prevention by Aggressive Reduction in Cholesterol Levels study. 
  • Higher mortality in pediatric and adult trauma patients with traumatic coagulopathy, using age-adjusted diagnostic criteria. 
  • How to interpret and pursue an abnormal prothrombin time, activated partial thromboplastin time, and bleeding time in adults. 
  • How to manage coagulopathies in critically ill patients. 
  • ISTH DIC subcommittee communication on anticoagulation in COVID-19. 
  • Immediate versus delayed coronary grafting after streptokinase treatment. Postoperative blood loss and clinical results. 
  • Implementation of a pediatric trauma massive transfusion protocol: one institution's experience. 
  • Improvements in early mortality and coagulopathy are sustained better in patients with blunt trauma after institution of a massive transfusion protocol in a civilian level I trauma center. 
  • Improving patient selection for coagulopathy testing in the setting of acute ischemic stroke. 
  • In Vitro Treatment of Extracorporeal Membrane Oxygenation Coagulopathy with Recombinant von Willebrand Factor or Lyophilized Platelets. 
  • Infectious and bleeding complications in patients with glycogenosis Ib. 
  • Intracerebral hematoma in a hemophiliac. Combined surgical and factor VIII treatment. 
  • Introduction to a review series on new therapeutics for inherited and acquired bleeding conditions. 
  • Isolation and characterization of an acquired antithrombin antibody. 
  • Key Pathogenic Factors in Coronavirus Disease 2019-Associated Coagulopathy and Acute Lung Injury Highlighted in a Patient With Copresentation of Acute Myelocytic Leukemia: A Case Report. 
  • Life threatening liver disease during treatment with monoclonal antibodies. 
  • Management of Coagulopathy in Postpartum Hemorrhage. 
  • Managing thrombosis and cardiovascular complications of COVID-19: answering the questions in COVID-19-associated coagulopathy. 
  • Measurement of fibrinogen degradation products. 
  • More than menorrhagia: a review of the obstetric and gynaecological manifestations of bleeding disorders. 
  • Multidisciplinary approach to the challenge of hemostasis. 
  • New criteria for sepsis-induced coagulopathy (SIC) following the revised sepsis definition: a retrospective analysis of a nationwide survey. 
  • New insights into the coagulation system and implications for new therapeutic options with recombinant factor VIIa. 
  • Obstetric management of adolescents with bleeding disorders. 
  • Pathogenetic and prognostic significance of altered coagulation and fibrinolysis in acute lung injury/acute respiratory distress syndrome. 
  • Pathophysiology of early trauma-induced coagulopathy: emerging evidence for hemodilution and coagulation factor depletion. 
  • Perceptions of quality health care among parents of children with bleeding disorders. 
  • Perioperative Considerations in Management of the Severely Bleeding Coagulopathic Patient. 
  • Perioperative coagulation management in the intensive care unit. 
  • Physician knowledge and practices in the evaluation of coagulopathies in stroke patients. 
  • Platelet Activation and Thrombosis in COVID-19. 
  • Precision Correction of Coagulopathy or Prothrombin Complex Concentrates?: Reversal Options for Dabigatran following Trauma. 
  • Preoperative coagulation testing on a gynecologic oncology service. 
  • Prevention and treatment of coagulopathy in patients receiving massive transfusions. 
  • Prohemostatic treatment in cardiac surgery. 
  • Prothrombin Complex Concentrate vs Plasma for Post-Cardiopulmonary Bypass Coagulopathy and Bleeding: A Randomized Clinical Trial. 
  • Protocolized hemostatic factor use in major thoracic aortic surgery. 
  • Purpura fulminans. 
  • RE: The prothrombin time ratio is not a more effective marker for evaluating sepsis-induced coagulopathy than fibrin-related markers: Response to the Letter-to-the-Editor by Dr Wada. 
  • Rapid evaluation of coagulopathies after cardiopulmonary bypass in children using modified thromboelastography. 
  • Recent developments in topical thrombins. 
  • Recombinant biologics for treatment of bleeding disorders. 
  • Recombinant factor VIIa in patients with coagulopathy secondary to anticoagulant therapy, cirrhosis, or severe traumatic injury: review of safety profile. 
  • Recombinant human soluble thrombomodulin in patients with sepsis-associated coagulopathy (SCARLET): an updated meta-analysis. 
  • Recurrent thrombosis of the superior vena cava associated with activated protein C resistance: imaging findings. 
  • Remodeling the blood coagulation cascade. 
  • Retrospective analysis of the incidence of epidural haematoma in patients with epidural catheters and abnormal coagulation parameters. 
  • Risk of Spinal Hematoma After Lumbar Puncture. 
  • Roles of Coagulation Abnormalities and Microthrombosis in Sepsis: Pathophysiology, Diagnosis, and Treatment. 
  • Rotational thromboelastometry-guided blood product management in major spine surgery. 
  • Sepsis-Induced Coagulopathy and Japanese Association for Acute Medicine DIC in Coagulopathic Patients with Decreased Antithrombin and Treated by Antithrombin. 
  • Sepsis-induced Coagulopathy and Disseminated Intravascular Coagulation. 
  • Severe coagulation abnormalities in Reye syndrome. 
  • Sometimes it is Not as Simple as Sepsis: An Unusual Cause of Coagulopathy. 
  • Spontaneous factor VIII inhibitor occurring in association with chronic graft-versus-host disease. 
  • Superficial migratory thrombophlebitis and the lupus anticoagulant. 
  • Suppression of Fibrinolysis and Hypercoagulability, Severity of Hypoxemia, and Mortality in COVID-19 Patients: A Retrospective Cohort Study. 
  • Systematic review of viscoelastic testing (TEG/ROTEM) in obstetrics and recommendations from the women's SSC of the ISTH. 
  • Technology: Is There Sufficient Evidence to Change Practice in Point-of-Care Management of Coagulopathy? 
  • The Neurostimulation Appropriateness Consensus Committee (NACC): Recommendations on Bleeding and Coagulation Management in Neurostimulation Devices. 
  • The authors reply. 
  • The authors reply. 
  • The coagulation cascade in cirrhosis. 
  • The coagulopathy of trauma versus disseminated intravascular coagulation. 
  • The coagulopathy, endotheliopathy, and vasculitis of COVID-19. 
  • The copperhead coagulopathy conundrum. 
  • The effect of fibrin-stabilizing factor on the subunit structure of human fibrin. 
  • The role of anti-fibrinolytics, rFVIIa and other pro-coagulants: prophylactic versus rescue? 
  • The role of viscoelastic testing in assessing peri-interventional platelet function and coagulation. 
  • The unique characteristics of COVID-19 coagulopathy. 
  • Therapeutic strategies in patients with coagulopathy and disseminated intravascular coagulation: awareness of the phase-dependent characteristics. 
  • Thromboelastography and rotational thromboelastometry in bleeding patients with coagulopathy: Practice management guideline from the Eastern Association for the Surgery of Trauma. 
  • Transfusion management of trauma patients. 
  • Trauma-induced coagulopathy. 
  • Unsupervised Analysis of Transcriptomics in Bacterial Sepsis Across Multiple Datasets Reveals Three Robust Clusters. 
  • Update on massive transfusion. 
  • Uses of antithrombin III concentrate in congenital and acquired deficiency states. 
  • Using Plasma and Prothrombin Complex Concentrates. 
  • Utility of viscoelastic coagulation testing in liver surgery: a systematic review. 
  • Viral-Induced Inflammatory Coagulation Disorders: Preparing for Another Epidemic. 
  • Viscoelastic Coagulation Testing: Use and Current Limitations in Perioperative Decision-making. 
  • Von Willebrand disease and other bleeding disorders in women: consensus on diagnosis and management from an international expert panel. 
  • Which approach to anticoagulation management is best? Illustration of an interactive mathematical model to support informed decision making. 
  • [Hematologic diseases: from within the heart]. 
• 

  Keywords of People

  • Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Hoffman, Maureane, Professor of Pathology, Integrative Immunobiology