Bone Resorption

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  Subject Areas on Research

  • 3D osteoarthritic changes in TMJ condylar morphology correlates with specific systemic and local biomarkers of disease. 
  • A quantitative histomorphometric comparison of 40 micron thick Paragon sections with 5 micron thick Goldner sections in the study of undecalcified bone. 
  • Acrylic fragmentation in total hip replacements and its biological consequences. 
  • Aged G Protein-Coupled Receptor Kinase 3 (Grk3)-Deficient Mice Exhibit Enhanced Osteoclastogenesis and Develop Bone Lesions Analogous to Human Paget's Disease of Bone. 
  • An evaluation of several biochemical markers for bone formation and resorption in a protocol utilizing cyclical parathyroid hormone and calcitonin therapy for osteoporosis. 
  • Anti-inflammatory and anti-osteoporotic activities of base-boronated nucleosides and phosphate-boronated nucleotides in rodents. 
  • Antiresorptive effect of a single infusion of microgram quantities of zoledronate in Paget's disease of bone. 
  • Antiresorptive pharmacotherapy in older women: where the evidence-based medicine rubber meets the geriatrics road. 
  • Association between blood lead and the risk of amyotrophic lateral sclerosis. 
  • Biomimetic polydopamine-laced hydroxyapatite collagen material orients osteoclast behavior to an anti-resorptive pattern without compromising osteoclasts' coupling to osteoblasts. 
  • Bone loss, pain and inflammation: three faces of ACPA in RA pathogenesis. 
  • Bone protection by inhibition of microRNA-182. 
  • Calcium stone disease: an overview. 
  • Cathepsin K-sensitive poly(ethylene glycol) hydrogels for degradation in response to bone resorption. 
  • Complications following pediatric cranioplasty after decompressive craniectomy: a multicenter retrospective study. 
  • Compression forces of internal and external ankle fixation devices with simulated bone resorption. 
  • Efficacy of alendronate in adults with cystic fibrosis with low bone density. 
  • Failure of autologous bone-assisted cranioplasty following decompressive craniectomy in children and adolescents. 
  • Glucocorticoid-induced osteoporosis: mechanisms for bone loss; evaluation of strategies for prevention. 
  • Increased Ca2+ signaling through CaV1.2 promotes bone formation and prevents estrogen deficiency-induced bone loss. 
  • Increased training loads do not magnify cancellous bone gains with rodent jump resistance exercise. 
  • Intact parathyroid hormone overestimates the presence and severity of parathyroid-mediated osseous abnormalities in uremia. 
  • Intestinal Inflammation Promotes MDL-1+ Osteoclast Precursor Expansion to Trigger Osteoclastogenesis and Bone Loss. 
  • Iron deficiency and high-intensity running interval training do not impact femoral or tibial bone in young female rats. 
  • Macrophage activation results in bone resorption. 
  • Mining the complexities of the estrogen signaling pathways for novel therapeutics. 
  • Molecular Mass-Dependent Resorption and Bone Regeneration of 3D Printed PPF Scaffolds in a Critical-Sized Rat Cranial Defect Model. 
  • NOTCH1 regulates osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblast lineage cells. 
  • Open-label trial evaluating the safety and efficacy of zoledronic acid in preventing bone loss in patients with hormone-sensitive prostate cancer and bone metastases. 
  • Osteoclast differentiation and function in aquaglyceroporin AQP9-null mice. 
  • Osteoporosis. 
  • Osteoprotegerin in bone metastases: mathematical solution to the puzzle. 
  • Porous metal metaphyseal cones for severe bone loss: when only metal will do. 
  • Quantification of condylar resorption in temporomandibular joint osteoarthritis. 
  • Replacement of intervertebral discs in chimpanzees by silicone-dacron implants: a preliminary report. 
  • Reprogrammed marrow adipocytes contribute to myeloma-induced bone disease. 
  • Role for endotoxin and complement in periodontal tissue destruction. 
  • Salmon calcitonin reduces vertebral bone loss in glucocorticoid-treated beagles. 
  • Simultaneous labeling of mast cell proteases and protease mRNAs at the bone-implant interface of aseptically loosened hip implants. 
  • Single infusion of zoledronate in Paget's disease of bone: a placebo-controlled, dose-ranging study. 
  • Skeletal complications in patients with bone metastases from renal cell carcinoma and therapeutic benefits of zoledronic acid. 
  • Spinal bone density following spinal fusion. 
  • Techniques for managing anatomic variations in primary total knee arthroplasty. 
  • The Effect of Subcritical Bone Loss and Exposure on Recurrent Instability After Arthroscopic Bankart Repair in Intercollegiate American Football. 
  • The Notch Ligand Jagged1 Regulates the Osteoblastic Lineage by Maintaining the Osteoprogenitor Pool. 
  • The cytoskeletal regulatory scaffold protein GIT2 modulates mesenchymal stem cell differentiation and osteoblastogenesis. 
  • The endogenous selective estrogen receptor modulator 27-hydroxycholesterol is a negative regulator of bone homeostasis. 
  • The incidence of osteonecrosis of the jaw in patients receiving 5 milligrams of zoledronic acid: data from the health outcomes and reduced incidence with zoledronic acid once yearly clinical trials program. 
  • The origins and roles of osteoclasts in bone development, homeostasis and repair. 
  • The oxysterol, 27-hydroxycholesterol, links cholesterol metabolism to bone homeostasis through its actions on the estrogen and liver X receptors. 
  • p38α MAPK Regulates Lineage Commitment and OPG Synthesis of Bone Marrow Stromal Cells to Prevent Bone Loss under Physiological and Pathological Conditions. 
  • p38α MAPK regulates proliferation and differentiation of osteoclast progenitors and bone remodeling in an aging-dependent manner. 
  • pH-Sensitive nanocarrier assisted delivery of adenosine to treat osteoporotic bone loss. 
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  Keywords of People

  • Gall, Ken, Professor in the Department of Mechanical Engineering and Materials Science, Thomas Lord Department of Mechanical Engineering and Materials Science
  • Hilton, Matthew James, Associate Professor in Orthopaedic Surgery, Cell Biology