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Subject Areas on Research
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Affinity of (alpha-P-borano)-NTP analogs to rabbit muscle pyruvate kinase.
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Anti-inflammatory activity of amine cyanoboranes, amine carboxyboranes, and related compounds.
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Antihyperlipidemic activity of amine cyanoboranes, amine carboxyboranes, and related compounds.
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Antineoplastic activity of a series of boron analogues of alpha-amino acids.
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Antineoplastic activity of tetrakis-mu-(trimethylamine-boranecarboxylato)-bis (trimethylamine-carboxyborane)dicopper (II) in Ehrlich ascites carcinoma.
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Borane-amine complexes--versatile reagents in the chemistry of nucleic acids and their analogs.
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Boranophosphates as mimics of natural phosphodiesters in DNA.
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Boron-containing oligodeoxyribonucleotide 14mer duplexes: enzymatic synthesis and melting studies.
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High potency silencing by single-stranded boranophosphate siRNA.
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Incorporation of ribonucleoside 5'-(alpha-P-borano)triphosphates into a 20-mer RNA by T7 RNA polymerase.
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One-pot synthesis of an AZT boranophosphate conjugated with tyrosine: a potential prodrug candidate.
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Phenylalanine hydroxylase activity in mammalian cells.
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Reading, writing, and modulating genetic information with boranophosphate mimics of nucleotides, DNA, and RNA.
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Synthesis and Properties of Novel Triphosphate Analogues: Ribonucleoside and Deoxyribonucleoside (α-P-borano, α-P-thio)triphosphates
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Synthesis of a novel nucleic acid mimic: P-boranomethylphosphonate.
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Synthesis of nucleoside 3',5'-cyclic boranophosphorothioate, a new type of cyclic nucleotide.
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Synthesis, Hydrolysis, and Protonation-Promoted Intramolecular Reductive Breakdown of Potential NRTIs: Stavudine α-P-Borano-γ-P-N-l-tryptophanyltriphosphates.
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The effect of a single boranophosphate substitution with defined configuration on the thermal stability and conformation of a DNA duplex.
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The synthesis and antineoplastic activity of 2'-deoxy-nucleoside-cyanoboranes in murine and human culture cells.
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Versatility of borane nucleic acids mimics for coding, decoding and modulating genetic information.