Boron Compounds
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Subject Areas on Research
- "Synthesis of 5-ethynyl-2'-deoxyuridine-5'-boranomonophosphate as a Potential Thymidylate Synthase Inhibitor"
- Anti-inflammatory and anti-osteoporotic activities of base-boronated nucleosides and phosphate-boronated nucleotides in rodents.
- Antineoplastic activity of boron-containing thymidine nucleosides in Tmolt3 leukemic cells.
- Antineoplastic activity of tetrakis-mu-(trimethylamine-boranecarboxylato)-bis (trimethylamine-carboxyborane)dicopper (II) in Ehrlich ascites carcinoma.
- Antiviral activity of mixed-valence rare earth borotungstate heteropoly blues against influenza virus in mice.
- Bacterial surface association of heat-labile enterotoxin through lipopolysaccharide after secretion via the general secretory pathway.
- Base-boronated dinucleotides: synthesis and effect of N7-cyanoborane substitution on the base protons.
- Boranophosphate nucleic acids--a versatile DNA backbone.
- Cardioprotective effects of iron chelator HAPI and ROS-activated boronate prochelator BHAPI against catecholamine-induced oxidative cellular injury.
- Cholecystokinin excites interneurons in rat basolateral amygdala.
- Comparison of various iron chelators and prochelators as protective agents against cardiomyocyte oxidative injury.
- Conformational ensemble of the human TRPV3 ion channel.
- Conformational studies of dithymidine boranomonophosphate diastereoisomers.
- Cytosolic delivery of macromolecules. II. Mechanistic studies with pH-sensitive morpholine lipids.
- Differential and simultaneous adenosine di- and triphosphate binding by MutS.
- Differential specificities and simultaneous occupancy of human MutSalpha nucleotide binding sites.
- Enantioselective diene Cyclization/Hydrosilylation catalyzed by optically active palladium bisoxazoline and pyridine-oxazoline complexes.
- Enzymatic polymerization of high molecular weight DNA amphiphiles that self-assemble into star-like micelles.
- Expression level is a key determinant of E2F1-mediated cell fate.
- Gamma-L-glutaminyl-3,4-benzoquinone. Structural studies and enzymatic synthesis.
- Hypolipidemic activity of boronated nucleosides and nucleotides in rodents.
- Inflammatory linear verrucous epidermal nevus treated successfully with crisaborole ointment in a 5-year-old boy.
- Introduction of the alpha-P-borano-group into deoxynucleoside triphosphates increases their selectivity to HIV-1 reverse transcriptase relative to DNA polymerases.
- LMP-420: a novel purine nucleoside analog with potent cytotoxic effects for CLL cells and minimal toxicity for normal hematopoietic cells.
- Luminescent Difluoroboron β-Diketonate PLA-PEG Nanoparticle.
- Luminescent difluoroboron β-diketonate PEG-PLA oxygen nanosensors for tumor imaging.
- Modifications of boronic ester pro-chelators triggered by hydrogen peroxide tune reactivity to inhibit metal-promoted oxidative stress.
- Multicolor in vitro translation.
- N7-cyanoborane-2'-deoxyguanosine 5'-triphosphate is a good substrate for DNA polymerase.
- Novel 3',5'-cyclic nucleotide analogue: adenosine 3',5'-cyclic boranomonophosphate.
- Phase 1 study of ixazomib, an investigational proteasome inhibitor, in advanced non-hematologic malignancies.
- Pore region of TRPV3 ion channel is specifically required for heat activation.
- Prochelator BHAPI protects cells against paraquat-induced damage by ROS-triggered iron chelation.
- Prochelators triggered by hydrogen peroxide provide hexadentate iron coordination to impede oxidative stress.
- RNA interference using boranophosphate siRNAs: structure-activity relationships.
- RNase H activation by stereoregular boranophosphate oligonucleotide.
- Sphingosine-1-phosphate phosphohydrolase regulates endoplasmic reticulum-to-golgi trafficking of ceramide.
- Studies on base-boronated oligonucleotides. 2 (1). Incompatibility of DMT and cyanoborane groups during oligonucleotide synthesis.
- Synthesis and separation of diastereomers of uridine 2',3'-cyclic boranophosphate.
- Synthesis of 5-(1-propynyl)-2'-deoxyuridine 5'-(alpha-P-borano)triphosphate and kinetic characterization as a substrate for mmlv reverse transcriptase.
- Synthesis of 5-substituted 2'-deoxycytidine 5'-(alpha-P-borano)triphosphates, their incorporationinto DNA and effects on exonuclease.
- Synthesis of acyclothymidine triphosphate and alpha-P-boranotriphosphate and their substrate properties with retroviral reverse transcriptase.
- Synthesis of new classes of boron-containing nucleotides.
- Synthesis of nucleoside boranophosphoramidate prodrugs conjugated with amino acids.
- Synthesis of oligonucleoside boranophosphates via an H-phosphonate method without nucleobase protection.
- The gap junction inhibitor 2-aminoethoxy-diphenyl-borate protects against acetaminophen hepatotoxicity by inhibiting cytochrome P450 enzymes and c-jun N-terminal kinase activation.
- The synthesis and anti-neoplastic activity of N2-isobutyryl-2'-deoxyguanosine-N7-cyanoborane derivatives.
- Two amino acid residues determine 2-APB sensitivity of the ion channels TRPV3 and TRPV4.
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Keywords of People
- Cianciolo, George James, Associate Professor Emeritus of Pathology, Pathology