Brachytherapy

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  Subject Areas on Research

  • 125I embedded in an orbital prosthesis for retreatment of recurrent retinoblastoma. 
  • 3-year follow-up of the SISR (Sirolimus-Eluting Stents Versus Vascular Brachytherapy for In-Stent Restenosis) trial. 
  • A comprehensive outlook on intracerebral therapy of malignant gliomas. 
  • A controlled study of efficacy of interstitial or external irradiation in a virus-induced brain-tumor model in rats. 
  • A descriptive analysis of postimplant dosimetric parameters from Radiation Therapy Oncology Group P0019. 
  • A greedy heuristic using adjoint functions for the optimization of seed and needle configurations in prostate seed implant. 
  • A histologic study (including DNA quantification and Ki-67 labeling index) in uveal melanomas after brachytherapy with ruthenium plaques. 
  • A novel needle-based miniature x-ray generating system. 
  • A phase II study of external beam radiotherapy combined with permanent source brachytherapy for intermediate-risk, clinically localized adenocarcinoma of the prostate: preliminary results of RTOG P-0019. 
  • A preliminary analysis of health-related quality of life in the first year after permanent source interstitial brachytherapy (PIB) for clinically localized prostate cancer. 
  • A prospective analysis of patient-reported quality of life after prostate brachytherapy. 
  • A prospective quality-of-life study in men with clinically localized prostate carcinoma treated with radical prostatectomy, external beam radiotherapy, or interstitial brachytherapy. 
  • A review on the management of epilepsy associated with hypothalamic hamartomas. 
  • A simple model predicts freedom from biochemical recurrence after low-dose rate prostate brachytherapy alone. 
  • A structured literature review to determine the use of the American Society for Therapeutic Radiology and Oncology consensus definition of biochemical failure. 
  • A systematic review of hypofractionation for primary management of prostate cancer. 
  • Ablative therapies for central airway obstruction. 
  • Accelerated partial breast irradiation after conservative surgery for breast cancer. 
  • Accelerator-based neutron brachytherapy. 
  • Acute urinary toxicity following transperineal prostate brachytherapy using a modified Quimby loading method. 
  • Adenocarcinoma of the retinal pigment epithelium: a diagnostic and therapeutic challenge. 
  • Advanced Treatment Technique for Locally Advanced Cervical Cancer: Time for a Standard of Care Shift? 
  • American Brachytherapy Society consensus guidelines for transrectal ultrasound-guided permanent prostate brachytherapy. 
  • American Society for Radiation Oncology (ASTRO) and American College of Radiology (ACR) practice guideline for the transperineal permanent brachytherapy of prostate cancer. 
  • An automated intensity-weighted brachytherapy seed localization algorithm. 
  • An investigation of a PRESAGE® in vivo dosimeter for brachytherapy. 
  • Anal cancer. American College of Radiology. ACR Appropriateness Criteria. 
  • Analysis of results of radiation therapy for stage IB carcinoma of the cervix. 
  • Application of Gafchromic film in the dosimetry of an intravascular brachytherapy source. 
  • Association Between Choice of Radical Prostatectomy, External Beam Radiotherapy, Brachytherapy, or Active Surveillance and Patient-Reported Quality of Life Among Men With Localized Prostate Cancer. 
  • Association between Tumor Regression Rate and Gene Expression Profile after Iodine 125 Plaque Radiotherapy for Uveal Melanoma. 
  • Astatine-211-labeled radiotherapeutics: an emerging approach to targeted alpha-particle radiotherapy. 
  • Biochemical recurrence after definitive prostate cancer therapy. Part II: treatment strategies for biochemical recurrence of prostate cancer. 
  • Biologically effective dose (BED) correlation with biochemical control after low-dose rate prostate brachytherapy for clinically low-risk prostate cancer. 
  • Body mass index, dose to organs at risk during vaginal brachytherapy, and the role of three-dimensional CT-based treatment planning. 
  • Brachytherapy using injectable seeds that are self-assembled from genetically encoded polypeptides in situ. 
  • COVID-19 impact on timing of brachytherapy treatment and strategies for risk mitigation. 
  • Calculation of brachytherapy doses does not need TG-43 factorization. For the proposition. 
  • Cancer control after low-dose-rate prostate brachytherapy performed by a multidisciplinary team with no previous prostate brachytherapy experience. 
  • Carcinoma of the cervix, stage III. Results of radiation therapy. 
  • Carcinoma of the cervix: analysis of bladder and rectal radiation dose and complications. 
  • Carcinoma of the cervix: patterns of care studies: review of 1978, 1983, and 1988-1989 surveys. 
  • Carcinoma of the prostate: the therapeutic dilemma. 
  • Carcinoma of the tonsillar region: a multivariate analysis of 243 patients treated with radical radiotherapy. 
  • Carcinoma of the uterine cervix: a 3D - CT analysis of dose to the internal, external and common iliac nodes in tandem and ovoid applications. 
  • Cervical Cancer, Version 3.2019, NCCN Clinical Practice Guidelines in Oncology. 
  • Challenges in Reporting the Effect of Radiotherapy on Erectile Function. 
  • Changes in insurance coverage for cancer patients receiving brachytherapy before and after enactment of the Affordable Care Act. 
  • Changes on Midchemoradiation Therapy Fluorodeoxyglucose Positron Emission Tomography for Cervical Cancer Are Associated with Prognosis. 
  • Chromosome 3 analysis of uveal melanoma using fine-needle aspiration biopsy at the time of plaque radiotherapy in 140 consecutive cases: the Deborah Iverson, MD, Lectureship. 
  • Clinicopathologic features and treatment in patients with early stage uterine clear cell carcinoma: A 16-year experience. 
  • Combination external beam radiation and brachytherapy boost with androgen deprivation for treatment of intermediate-risk prostate cancer: long-term results of CALGB 99809. 
  • Combination external beam radiation and brachytherapy boost with androgen suppression for treatment of intermediate-risk prostate cancer: an initial report of CALGB 99809. 
  • Comments on: High-dose-rate interstitial brachytherapy as monotherapy in one fraction of 20.5 Gy for the treatment of localize prostate cancer: toxicity and 6-years biochemical results. 
  • Commissioning a CT-compatible LDR tandem and ovoid applicator using Monte Carlo calculation and 3D dosimetry. 
  • Comparative analysis of prostate-specific antigen free survival outcomes for patients with low, intermediate and high risk prostate cancer treatment by radical therapy. Results from the Prostate Cancer Results Study Group. 
  • Comparing radical prostatectomy and brachytherapy for localized prostate cancer. 
  • Comparison of radical prostatectomy and iodine 125 interstitial radiotherapy for the treatment of clinically localized prostate cancer: a 7-year biochemical (PSA) progression analysis. 
  • Computed axial tomography tandem and ovoids (CATTO) dosimetry: three-dimensional assessment of bladder and rectal doses. 
  • Consensus statement on palliative lung radiotherapy: third international consensus workshop on palliative radiotherapy and symptom control. 
  • Counterpoints: Which should be used first in symptomatic metastatic castration-resistant prostate cancer, docetaxel or radium? Radium-223 is the preferred therapy in bone-predominant symptomatic metastatic castration-resistant prostate cancer. 
  • Current salvage methods for recurrent prostate cancer after failure of primary radiotherapy. 
  • Design of a plastic minicolpostat applicator with shields. 
  • Development of a Multi-Institutional Simulation-Based Gynecologic Brachytherapy Curriculum. 
  • Dosimetric characteristics of the Novoste Beta-Cath 90Sr/Y source trains at submillimeter distances. 
  • Dosimetric quantifiers for low-dose-rate prostate brachytherapy: is V(100) superior to D(90)? 
  • Dosimetry and cancer control after low-dose-rate prostate brachytherapy. 
  • Early macular morphological changes following plaque radiotherapy for uveal melanoma. 
  • Early quality of life assessment in men treated with permanent source interstitial brachytherapy for clinically localized prostate cancer. 
  • Editorial comment. 
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  • Editorial comment. Acute lower urinary tract symptoms after prostate brachytherapy with cesium-131. 
  • Efficacy and Safety of Low-Dose Iodine Plaque Brachytherapy for Juxtapapillary Choroidal Melanoma. 
  • Endobronchial interstitial Au-198 implantation in the treatment of recurrent bronchogenic carcinoma. 
  • Erectile function outcome reporting after clinically localized prostate cancer treatment. 
  • Evaluating glioma therapies: modeling treatments and predicting outcomes. 
  • Experimental 3D dosimetry around a high-dose-rate clinical 192Ir source using a polyacrylamide gel (PAG) dosimeter. 
  • External beam radiation followed by planned neck dissection and brachytherapy for base of tongue squamous cell carcinoma. 
  • Externally applied high-dose-rate brachytherapy for deeply invasive cutaneous squamous cell carcinoma in an older patient. 
  • Ferromagnetic hyperthermia and iodine 125 brachytherapy in the treatment of choroidal melanoma in a rabbit model. 
  • Five-year follow-up of the Sirolimus-Eluting Stents vs Vascular Brachytherapy for Bare Metal In-Stent Restenosis (SISR) trial. 
  • Focal therapy for prostate cancer. 
  • Gastrointestinal toxicity of transperineal interstitial prostate brachytherapy. 
  • Guideline for the management of clinically localized prostate cancer: 2007 update. 
  • Health-related quality of life in men receiving prostate brachytherapy on RTOG 98-05. 
  • High dose rate intraoperative radiotherapy for recurrent cervical cancer and nodal disease. 
  • High-Risk Prostate Cancer: Role of Radical Prostatectomy and Radiation Therapy. 
  • High-volume providers and brachytherapy practice: A Medicare provider utilization and payment analysis. 
  • Ice as a water-equivalent solid medium for brachytherapy dosimetric measurements. 
  • Image-guided brachytherapy for gynecologic surgeons. 
  • Impact of Chemotherapy and Radiotherapy on Management of Early Stage Clear Cell and Papillary Serous Carcinoma of the Uterus. 
  • Impact of comorbidity on health-related quality of life after prostate cancer treatment: combined analysis of two prospective cohort studies. 
  • Improving calibration accuracy in gel dosimetry. 
  • In regard to Brenner et al. Direct evidence that prostate tumors show high sensitivity to fractionation (low alpha/beta ratio) similar to late-responding normal tissue. 
  • In regard to Ghaly et al., IJROBP 2003;55:1288-1293. 
  • In regard to Lee et al.: "Dosimetry and cancer control after low-dose-rate prostate brachytherapy" (Int J Radiat Oncol Biol Phys 2005;61:52-59). 
  • Incorporating patient-specific CT-based ophthalmic anatomy in modeling iodine-125 eye plaque brachytherapy dose distributions. 
  • Injectable polypeptide micelles that form radiation crosslinked hydrogels in situ for intratumoral radiotherapy. 
  • Intensity-modulated radiation therapy in gynecologic malignancies. 
  • Internal radiation for bile duct cancer. 
  • International practice survey on palliative lung radiotherapy: third international consensus workshop on palliative radiotherapy and symptom control. 
  • Interobserver variability leads to significant differences in quantifiers of prostate implant adequacy. 
  • Interstitial brachytherapy for prostate cancer--just an expensive variant of 'watchful waiting'? 
  • Interstitial hyperthermia and iridium brachytherapy in treatment of malignant glioma. A phase I clinical trial. 
  • Interstitial hyperthermia in combination with brachytherapy. 
  • Interstitial implant alone or in combination with external beam radiation therapy for intermediate-risk prostate cancer: a survey of practice patterns in the United States. 
  • Interstitial microwave-induced hyperthermia and iridium brachytherapy for the treatment of obstructing biliary carcinomas. 
  • Intracoronary brachytherapy: time to sell short? 
  • Intraoperative interstitial microwave-induced hyperthermia and brachytherapy. 
  • Intraoperative irradiation: current and future status. 
  • Intraoperative pelvic brachytherapy for treatment of locally advanced or recurrent colorectal cancer. 
  • Intraoperative radiation therapy. 
  • Intraperitoneal chromic phosphate P 32 suspension therapy of malignant peritoneal cytology in endometrial carcinoma. 
  • Intravascular radiation therapy after balloon angioplasty of narrowed femoropopliteal arteries to prevent restenosis: results of the PARIS feasibility clinical trial. 
  • Intravitreal triamcinolone acetonide for acute radiation papillopathy. 
  • Intravitreal triamcinolone acetonide for radiation maculopathy after plaque radiotherapy for choroidal melanoma. 
  • Iodine-125 interstitial irradiation of virally induced dog brain tumours. 
  • Is age a prognostic biomarker for survival among women with locally advanced cervical cancer treated with chemoradiation? An NRG Oncology/Gynecologic Oncology Group ancillary data analysis. 
  • Is radiation therapy required for patients with intermediate-risk rectal cancer? 
  • Late onset of isolated central nervous system metastasis of liposarcoma--a case report. 
  • Late toxicity and biochemical recurrence after external-beam radiotherapy combined with permanent-source prostate brachytherapy: analysis of Radiation Therapy Oncology Group study 0019. 
  • Leiomyosarcoma in childhood and adolescence. 
  • Localization of brachytherapy seeds in MRI by deconvolution. 
  • Long-term results of a phase II trial of ultrasound-guided radioactive implantation of the prostate for definitive management of localized adenocarcinoma of the prostate (RTOG 98-05). 
  • Long-term results of an RTOG Phase II trial (00-19) of external-beam radiation therapy combined with permanent source brachytherapy for intermediate-risk clinically localized adenocarcinoma of the prostate. 
  • Magnetic resonance imaging of juxtapapillary plaques in cadaver eyes. 
  • Measured TG-60 dosimetric parameters of the Novoste Beta-Cath 90Sr/Y source trains for intravascular brachytherapy. 
  • Medical malpractice and prostate brachytherapy. 
  • Morbidity and prostate-specific antigen control of external beam radiation therapy plus low-dose-rate brachytherapy boost for low, intermediate, and high-risk prostate cancer. 
  • Multi-center analysis of intraocular biopsy technique and outcomes for uveal melanoma: Ocular Oncology Study Consortium report 4. 
  • Multifocal iris melanoma in a 2-year-old managed with I-125 plaque brachytherapy. 
  • Multiple-fraction-per-day external beam radiotherapy for adults with supratentorial malignant gliomas. 
  • NCCN Guidelines Insights: Uveal Melanoma, Version 1.2019. 
  • New NCCN Guidelines for Uveal Melanoma and Treatment of Recurrent or Progressive Distant Metastatic Melanoma. 
  • New and Established Technology in Focal Ablation of the Prostate: A Systematic Review. 
  • New and recurrent tumors in germinal retinoblastoma: is there a treatment effect? 
  • Off-study utilization of experimental therapies: Analysis of GOG249-eligible cohorts using real world data. 
  • On the feasibility of polyurethane based 3D dosimeters with optical CT for dosimetric verification of low energy photon brachytherapy seeds. 
  • Open-configuration MR imaging, intervention, and surgery of the urinary tract. 
  • Optimization of a 90Sr/90Y radiation source train stepping for intravascular brachytherapy. 
  • Overpriced technology in radiation oncology. 
  • Overview consensus statement. Newer approaches to androgen deprivation therapy in prostate cancer. 
  • Part II: Sealing holes in the safety net. 
  • Particle therapy and treatment of cancer. 
  • Pathologic Malgaigne fracture following pelvic irradiation. A case report. 
  • Patterns and sites of failure in cervix cancer treated in the U.S.A. in 1978. 
  • Percentage of positive biopsies associated with freedom from biochemical recurrence after low-dose-rate prostate brachytherapy alone for clinically localized prostate cancer. 
  • Periocular triamcinolone for prevention of macular edema after iodine 125 plaque radiotherapy of uveal melanoma. 
  • Periocular triamcinolone for prevention of macular edema after plaque radiotherapy of uveal melanoma: a randomized controlled trial. 
  • Permanent source brachytherapy for prostate cancer. American College of Radiology. ACR Appropriateness Criteria. 
  • Point: radical prostatectomy is the treatment of choice for high-risk prostate cancer patients. 
  • Postimplant analysis of transperineal interstitial permanent prostate brachytherapy: evidence for a learning curve in the first year at a single institution. 
  • Preclinical assessment of comfort and secure fit of thermobrachytherapy surface applicator (TBSA) on volunteer subjects. 
  • Predictors of severe gastrointestinal toxicity after external beam radiotherapy and interstitial brachytherapy for advanced or recurrent gynecologic malignancies. 
  • Pretreatment prostate-specific antigen velocity is associated with freedom from biochemical recurrence of prostate cancer after low-dose-rate prostate brachytherapy alone. 
  • Prostate brachytherapy: a descriptive analysis from CaPSURE. 
  • Prostate cancer, Version 3.2012: featured updates to the NCCN guidelines. 
  • Prostate specific antigen only progression of prostate cancer. 
  • Prostatectomy vs brachytherapy for localized prostate cancer. 
  • Prostatic carcinosarcoma 15 years after combined external beam radiation and brachytherapy for prostatic adenocarcinoma: a case report. 
  • Quality of life after prostate cancer treatment. 
  • Radiation Therapy for Soft Tissue Sarcoma: Indications and Controversies for Neoadjuvant Therapy, Adjuvant Therapy, Intraoperative Radiation Therapy, and Brachytherapy. 
  • Radiation dose to the neurovascular bundles or penile bulb does not predict erectile dysfunction after prostate brachytherapy. 
  • Radiation therapy for prostate cancer. 
  • Radiation therapy in the treatment of cholangiocarcinoma. 
  • Radiation therapy of sarcomas of the soft tissues. 
  • Radical prostatectomy versus radiation therapy: can pretreatment nomograms be used to select the appropriate prostate cancer treatment? 
  • Radical radiotherapy for T4 carcinoma of the skin of the head and neck: a multivariate analysis. 
  • Radioactive sources embedded in suture are associated with improved postimplant dosimetry in men treated with prostate brachytherapy. 
  • Radiotherapy alone for carcinoma of the vagina: the importance of overall treatment time. 
  • Radiotherapy in the treatment of patients with unresectable extrahepatic cholangiocarcinoma. 
  • Re: Dosimetric consequences of increased seed strength for I-125 prostate implants. Radiother Oncol. 2003 Sep;68(3):295-7. 
  • Re: Radical Prostatectomy, External Beam Radiotherapy, or External Beam Radiotherapy with Brachytherapy Boost and Disease Progression and Mortality in Patients with Gleason Score 9-10 Prostate Cancer. 
  • Real-time dose-rate monitoring with gynecologic brachytherapy: Results of an initial clinical trial. 
  • Recent advances in the treatment of prostate cancer. 
  • Rectourethral fistula after combination radiotherapy for prostate cancer. 
  • Reducing biochemical recurrence rates in EBRT-treated prostate cancer patients: the influence of dose and dose per fraction. 
  • Regression of uveal melanoma after plaque radiotherapy and thermotherapy based on chromosome 3 status. 
  • Resident-reported brachytherapy experience in ACGME-accredited radiation oncology training programs. 
  • Response to Dr Sabater. 
  • Results from the Quality Research in Radiation Oncology (QRRO) survey: Evaluation of dosimetric outcomes for low-dose-rate prostate brachytherapy. 
  • Results of a phase II trial of transrectal ultrasound-guided permanent radioactive implantation of the prostate for definitive management of localized adenocarcinoma of the prostate (radiation therapy oncology group 98-05). 
  • Results of high dose rate brachytherapy, anterior pelvic exenteration and external beam radiotherapy for carcinoma of the female urethra. 
  • Risk of death from prostate cancer after radical prostatectomy or brachytherapy in men with low or intermediate risk disease. 
  • Robotic ultrasound and needle guidance for prostate cancer management: review of the contemporary literature. 
  • Salvage prostate cryoablation after primary interstitial brachytherapy failure: a feasible approach. 
  • Sector laser photocoagulation for the prevention of macular edema after plaque radiotherapy for uveal melanoma: a pilot study. 
  • Selection bias, survival, and brachytherapy for glioma. 
  • Sirolimus-eluting stents vs vascular brachytherapy for in-stent restenosis within bare-metal stents: the SISR randomized trial. 
  • Soft tissue complication rates after low dose rate brachytherapy using customized perineal templates. 
  • Spatiotemporally photoradiation-controlled intratumoral depot for combination of brachytherapy and photodynamic therapy for solid tumor. 
  • Stage II uterine papillary serous carcinoma: Carboplatin/paclitaxel chemotherapy improves recurrence and survival outcomes. 
  • Statin use is associated with decreased prostate cancer recurrence in men treated with brachytherapy. 
  • Surgical management of strabismus following choroidal melanoma plaque brachytherapy. 
  • Surveillance after prostate focal therapy. 
  • Susceptibility-based positive contrast MRI of brachytherapy seeds. 
  • Targeted Anterior Gland Focal Therapy-a Novel Treatment Option for a Better Defined Disease. 
  • Technical considerations in the application of intensity-modulated radiotherapy as a concomitant integrated boost for locally-advanced cervix cancer. 
  • The 1999 patterns of care study of radiotherapy in localized prostate carcinoma: a comprehensive survey of prostate brachytherapy in the United States. 
  • The Unique Issues With Brachytherapy in Low- and Middle-Income Countries. 
  • The anatomy of radiation oncology residency training. 
  • The effect of ambient pressure on well chamber response: Monte Carlo calculated results for the HDR 1000 plus. 
  • The effect of ambient pressure on well chamber response: experimental results with empirical correction factors. 
  • The influence of radiation modality and lymph node dissection on survival in early-stage endometrial cancer. 
  • The number of high-risk factors and the risk of prostate cancer-specific mortality after brachytherapy: implications for treatment selection. 
  • The role of androgen deprivation therapy combined with prostate brachytherapy. 
  • Thermal characteristics of thermobrachytherapy surface applicators for treating chest wall recurrence. 
  • Three-dimensional applicator system for carcinoma of the uterine cervix. 
  • Three-dimensional localisation based on projectional and tomographic image correlation: an application for digital tomosynthesis. 
  • Tracking brachytherapy sources using emission imaging with one flat panel detector. 
  • Transperineal templates for brachytherapy treatment of pelvic malignancies--a comparison of standard and customized templates. 
  • Treatment planning for prostate brachytherapy using region of interest adjoint functions and a greedy heuristic. 
  • Update on brachytherapy in localized prostate cancer: the importance of dosimetry. 
  • Urethroplasty for radiotherapy induced bulbomembranous strictures: a multi-institutional experience. 
  • Uterine Neoplasms. Clinical Practice Guidelines in Oncology. 
  • Uterine perforation by an intracavitary tandem: CT demonstration. 
  • Uveal melanoma treated with iodine-125 episcleral plaque: an analysis of dose on disease control and visual outcomes. 
  • Vaginal Dose Is Associated With Toxicity in Image Guided Tandem Ring or Ovoid-Based Brachytherapy. 
  • Variables in predicting survival based on treating "PSA-only" relapse. 
  • Yttrium-90 radioembolization of malignant tumors of the liver: gallbladder effects. 
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  Keywords of People

  • Badea, Cristian Tudorel, Professor in Radiology, Biomedical Engineering
  • Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Craciunescu, Oana, Professor of Radiation Oncology, Radiation Oncology
  • Koontz, Bridget Fey, Associate Professor of Radiation Oncology, Radiation Oncology
  • Mruthyunjaya, Prithvi, Adjunct Associate Professor in the Department of Ophthalmology, Ophthalmology, Vitreoretinal Diseases & Surgery
  • Stinnett, Sandra Sue, Associate Professor of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics
  • Sullivan, Daniel Carl, Professor Emeritus of Radiology, Radiology