Bradykinin

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  Subject Areas on Research

  • A kallikrein-targeting RNA aptamer inhibits the intrinsic pathway of coagulation and reduces bradykinin release. 
  • An overview of novel therapies for acute hereditary angioedema. 
  • Analysis of responses to bradykinin in the pulmonary vascular bed of the cat. 
  • Arachidonic acid metabolism in cultured aortic endothelial cells. Effect of cAMP and 3-isobutyl-1-methylxanthine. 
  • Arteriolar reactive hyperemia: modification by inhibitors of prostaglandin synthesis. 
  • Biochemical and pharmacological characterization of the human bradykinin subtype 2 receptor produced in mammalian cells using the Semliki Forest virus system. 
  • Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition. 
  • Bradykinin enhances AMPA and NMDA receptor activity in spinal cord dorsal horn neurons by activating multiple kinases to produce pain hypersensitivity. 
  • Bradykinin produces pain hypersensitivity by potentiating spinal cord glutamatergic synaptic transmission. 
  • Bradykinin receptor subtype 1 expression and function in prostate cancer. 
  • Bradykinin stimulation of inositol polyphosphate production in porcine aortic endothelial cells. 
  • Bradykinin type 2 receptor BE1 genotype influences bradykinin-dependent vasodilation during angiotensin-converting enzyme inhibition. 
  • Bradykinin: effect on ureteral peristalsis. 
  • Bronchial edema alters (99m)Tc-DTPA clearance from the airway surface in sheep. 
  • Capillary zone electrophoretic detection of biological thiols and their S-nitrosated derivatives. 
  • Colonic irritation in the rat sensitizes urinary bladder afferents to mechanical and chemical stimuli: an afferent origin of pelvic organ cross-sensitization. 
  • Comparative effects of L-NNA and alkyl esters of L-NNA on pulmonary vasodilator responses to ACh, BK, and SP. 
  • Crustacean peptide and peptide-like pheromones and kairomones. 
  • Effect of temperature on bradykinin-induced arachidonate release and calcium mobilization in vascular endothelial cells. 
  • Effects of bradykinin on the hemodynamics of tumor and granulating normal tissue microvasculature. 
  • Effects of distention and short-term grafting on vasoreactivity in rabbit external jugular veins. 
  • Extracellular caspase-6 drives murine inflammatory pain via microglial TNF-α secretion. 
  • Hemodynamic effects of vasorelaxant compounds in mice lacking one, two or all three angiotensin II receptors. 
  • Hereditary angiodema: a current state-of-the-art review, VI: novel therapies for hereditary angioedema. 
  • Hereditary angioedema: the rewards of studying a rare disease. 
  • Heterozygous cellular glutathione peroxidase deficiency in the mouse: abnormalities in vascular and cardiac function and structure. 
  • Human cardiac fibroblasts and receptors for angiotensin II and bradykinin: a potential role for bradykinin in the modulation of cardiac extracellular matrix. 
  • Hypercholesterolemia and experimental vein grafts: accelerated development of intimal hyperplasia and an increase in abnormal vasomotor function. 
  • Influence of group B streptococci on piglet pulmonary artery response to bradykinin. 
  • Inhibition of bradykinin vasodilation and potentiation of norepinephrine and angiotensin vasoconstriction by inhibitors of prostaglandin synthesis in skeletal muscle of the rat. 
  • Intracarotid RMP-7 enhanced indocyanine green staining of tumors in a rat glioma model. 
  • Investigation of the role of prostaglandins in nitroglycerin-induced relaxation of isolated rabbit blood vessels. 
  • Isoproterenol inhibits the increase in microvascular membrane permeability produced by bradykinin. 
  • Lipopolysaccharide upregulates bradykinin 1 receptors in the isolated mouse bladder. 
  • Management of Children With Hereditary Angioedema Due to C1 Inhibitor Deficiency. 
  • Mechanism of bradykinin-stimulated prostacyclin synthesis in porcine aortic endothelial cells. 
  • Mechanism of calcium influx in endothelial cells: role of intracellular calcium. 
  • Mechanisms of prostanoid synthesis in human synovial cells: cytokine-peptide synergism. 
  • Microcirculatory effects of prostaglandins E1, E2, and A1 in the rat mesentery and cremaster muscle. 
  • N omega-nitro-L-arginine methyl ester selectively inhibits pulmonary vasodilator responses to acetylcholine and bradykinin. 
  • Neurogenic inflammation and pancreatitis. 
  • New therapies for hereditary angioedema: disease outlook changes dramatically. 
  • Pathophysiologic and therapeutic importance of tissue ACE: a consensus report. 
  • Pharmacologic activation of the human coronary microcirculation in vitro: endothelium-dependent dilation and differential responses to acetylcholine. 
  • Potentiation of calcium levels by extracellular arachidonic acid in nuclei isolated from macrophages stimulated with receptor-recognized forms of alpha(2)-macroglobulin. 
  • Pregnancy and estradiol decrease GTPase activity in the guinea pig uterine artery. 
  • Prostaglandin E-1: a potential mediator of the inflammatory response. 
  • Regulation of adrenergic receptor function by phosphorylation. I. Agonist-promoted desensitization and phosphorylation of alpha 1-adrenergic receptors coupled to inositol phospholipid metabolism in DDT1 MF-2 smooth muscle cells. 
  • Regulation of arachidonic acid release in vascular endothelium. Ca(2+)-dependent and -independent pathways. 
  • Regulation of extracellular calcium entry in endothelial cells: role of intracellular calcium pool. 
  • Relaxant effect of diazepam on uterine muscle. 
  • Serotonin-bradykinin synergism in the mammalian capillary bed. 
  • Simultaneous measurement of liposome extravasation and content release in tumors. 
  • Soluble recombinant neutral endopeptidase (CD10) as a potential antiinflammatory agent. 
  • The acute nociceptive signals induced by bradykinin in rat sensory neurons are mediated by inhibition of M-type K+ channels and activation of Ca2+-activated Cl- channels. 
  • The role of calcium in the regulation of prostacyclin synthesis by porcine aortic endothelial cells. 
  • The structure of the neuropeptide bradykinin bound to the human G-protein coupled receptor bradykinin B2 as determined by solid-state NMR spectroscopy. 
  • Tunicamycin increases intracellular calcium levels in bovine aortic endothelial cells. 
  • Uterine relaxant properties of bradykinin in vitro. 
  • Vasoinhibitory action of proteolytic enzyme inhibitors in the capillary bed. 
  • Voltage dependence of bovine pulmonary artery endothelial cell function. 
  • [Bradykinin modulates ion channel in inflammatory pain].