Brain Diseases

• 

  Subject Areas on Research

  • 3-Dimensional visualization of lesions in rat brain using magnetic resonance imaging microscopy. 
  • A case of reversible posterior leukoencephalopathy syndrome caused by transient hypercoagulable state induced by infection. 
  • A comparative clinicopathologic study of endogenous mycotic endophthalmitis: variations in clinical and histopathologic changes in candidiasis compared to aspergillosis. 
  • A comparison of remifentanil and fentanyl in patients undergoing surgery for intracranial mass lesions. 
  • A neuroradiology self-assessment module for use in emergency radiology. 
  • A role for maternal serum screening in detecting chromosomal abnormalities in fetuses with isolated choroid plexus cysts: a prospective multicentre study. 
  • A unified framework for personalized regions selection and functional relation modeling for early MCI identification. 
  • ACR Appropriateness Criteria® Acute Mental Status Change, Delirium, and New Onset Psychosis. 
  • Acute neurotoxicity after intrathecal cytosine arabinoside in two adolescents with acute lymphoblastic leukemia of B-cell type. 
  • Acute visual loss and other disorders of the eyes. 
  • Additional evidence that PGAP1 loss of function causes autosomal recessive global developmental delay and encephalopathy. 
  • Adjunctive hyperbaric oxygen for treatment of rhinocerebral mucormycosis. 
  • Advance Directives and the Personal Identity Problem 
  • Advances in pediatric neuroradiology: highlights of the recent medical literature. 
  • Adverse cerebral outcomes after coronary bypass surgery. Multicenter Study of Perioperative Ischemia Research Group and the Ischemia Research and Education Foundation Investigators. 
  • American Society of Functional Neuroradiology-Recommended fMRI Paradigm Algorithms for Presurgical Language Assessment. 
  • Amylaceous (polyglucosan) bodies in familial cerebral atrophy of early onset. 
  • An association between fetal parvovirus B19 infection and fetal anomalies: a report of two cases. 
  • Analysis of shared heritability in common disorders of the brain. 
  • Anatomic applications of xenon-enhanced CT scanning: visual image analysis and brain-blood partition coefficient studies in man. 
  • Antiphospholipid antibodies in patients without systemic lupus erythematosus: neuroradiologic findings. 
  • Applications of transcranial magnetic stimulation and magnetic seizure therapy in the study and treatment of disorders related to cerebral aging. 
  • Astrocytic activation as evidence for brain damage. 
  • Benign intracranial hypertension. Pseudotumor cerebri from obstruction of dural sinuses. 
  • Brain and spine imaging findings in AIDS patients. 
  • Brain computerized tomography after hyperbaric oxygen therapy for carbon monoxide poisoning. 
  • Brain-machine interfaces: past, present and future. 
  • Breath-hold diving and cerebral decompression illness. 
  • Calcium and vitamin D intakes may be positively associated with brain lesions in depressed and nondepressed elders. 
  • Cause Unknown, Treatment Uncertain, Outcome Poor: An Encounter With Kidney Failure in the Developing World. 
  • Cell-based interventions for neurologic conditions: ethical challenges for early human trials. 
  • Cellular and molecular basis of epilepsy. 
  • Centennial dissertation. Honoring Arthur W. Goodspeed, MD and James B. Bullitt, MD. CT and MR imaging and nontraumatic neurologic emergencies. 
  • Central nervous system complications of cardiac surgery. 
  • Central nervous system pneumocystosis in a patient with AIDS. 
  • Central neurotoxicity after exposure to organic lead: susceptibility to seizures. 
  • Cerebral aneurysms: mechanisms of injury and critical care interventions. 
  • Cerebral blood flow and metabolism during cardiopulmonary bypass. 
  • Cerebral blood flow requirement for brain viability in newborn infants is lower than in adults. 
  • Cerebral imaging of decompression injury patients with 18-F-2-fluoro-2-deoxyglucose positron emission tomography. 
  • Cerebral oxygen metabolism in newborns. 
  • Cerebral phaeohyphomycosis in an immunodeficient child treated medically with combination antifungal therapy. 
  • Cerebral physiologic effects of burst suppression doses of propofol during nonpulsatile cardiopulmonary bypass. CNS Subgroup of McSPI. 
  • Cerebral white matter lesions, retinopathy, and stroke. 
  • Cerebrospinal fluid atrial natriuretic factor in intracranial disease. 
  • Cerebrospinal fluid proteomics in children during induction for acute lymphoblastic leukemia: A pilot study. 
  • Characterization of Death in Neonatal Encephalopathy in the Hypothermia Era. 
  • Cholesterol granuloma of the lateral ventricle. Case report. 
  • Clinical Reasoning: A 2-Day-Old Boy With Sudden Cardiac Arrest and Encephalopathy. 
  • Clinical applications of neuroimaging in psychiatry. 
  • Clinical prediction of functional outcome after ischemic stroke: the surprising importance of periventricular white matter disease and race. 
  • Cognitive effects of neonatal hippocampal lesions in a rat model of schizophrenia. 
  • Colloid cyst of the third ventricle presenting as a ring-enhancing lesion on computed tomography. 
  • Communication Challenges in Neonatal Encephalopathy. 
  • Comparison of seizures and brain lesions produced by intracerebroventricular kainic acid and bicuculline methiodide. 
  • Comparison of two brief tests of organic brain impairment, the MSQ and the short portable MSQ. 
  • Complex choristoma of the gyrus rectus: a distinct clinicopathologic entity? 
  • Complications following pediatric cranioplasty after decompressive craniectomy: a multicenter retrospective study. 
  • Comprehensive processing, display and analysis for in vivo MR spectroscopic imaging. 
  • Computed tomography brain scanning in alcohol withdrawal seizures. Value of the neurologic examination. 
  • Consensus statement on continuous EEG in critically ill adults and children, part I: indications. 
  • Consensus statement on continuous EEG in critically ill adults and children, part II: personnel, technical specifications, and clinical practice. 
  • Cranial computed tomography before lumbar puncture: a prospective clinical evaluation. 
  • Creatine kinase brain isoenzyme: relationship of cerebrospinal fluid concentration to the neurologic condition of newborns and cellular localization in the human brain. 
  • Critical care perspective on immunotherapy in lung transplantation. 
  • Cyst of the velum interpositum: antenatal ultrasonographic features and differential diagnosis. 
  • De novo variants in SNAP25 cause an early-onset developmental and epileptic encephalopathy. 
  • Defects of ocular motility after stereotactic midbrain lesions in man. 
  • Delayed-onset movement disorder and encephalopathy after oxycodone ingestion. 
  • Delayed-onset progressive movement disorders after static brain lesions. 
  • Development of a semi-automated method for quantification of MRI gray and white matter lesions in geriatric subjects. 
  • Diagnosis and neuroanatomical correlates of depression in brain-damaged patients. Implications for a neurology of depression. 
  • Differences in blood pressure by measurement technique in neurocritically ill patients: A technological assessment. 
  • Differential response of ventral midbrain and striatal progenitor cells to lesions of the nigrostriatal dopaminergic projection. 
  • Diffusion tensor imaging for evaluation of the childhood brain and pediatric white matter disorders. 
  • Disorders of acid-base relationships in the cerebrospinal fluid: a review. 
  • Disseminated aspergillosis involving the brain: distribution and imaging characteristics. 
  • Does this patient with headache have a migraine or need neuroimaging? 
  • ENIGMA and the individual: Predicting factors that affect the brain in 35 countries worldwide. 
  • Early onset severe ATP1A2 epileptic encephalopathy: Clinical characteristics and underlying mutations. 
  • Effect of intravenous lidocaine on the transcerebral inflammatory response during cardiac surgery: a randomized-controlled trial. 
  • Effect of kainic acid-induced status epilepticus on inositol-trisphosphate and seizure-induced brain damage in mature and immature animals. 
  • Effects of NMDA receptor antagonists and body temperature in the gerbil carotid occlusion model of transient forebrain ischemia. 
  • Elevated serum levels of tumor necrosis factor are associated with progressive encephalopathy in children with acquired immunodeficiency syndrome. 
  • Emerging Role of PD-1 in the Central Nervous System and Brain Diseases. 
  • Epileptic encephalopathy with features of rapid-onset dystonia Parkinsonism and alternating hemiplegia of childhood: a novel combination phenotype associated with ATP1A3 mutation. 
  • Ethical considerations in the care of encephalopathic neonates treated with therapeutic hypothermia. 
  • Evaluation of the patient with nontraumatic headache: an evidence based approach. 
  • Evaluation of thiamine for the prevention of ifosfamide-induced encephalopathy. 
  • FDG-PET in the selection of brain lesions for biopsy. 
  • Familial leukoencephalopathy in bipolar disorder. 
  • Fast spin-echo, magnetic resonance imaging-measured hippocampal volume: correlation with neuronal density in anterior temporal lobectomy patients. 
  • Fetal choroid plexus lesions. Relationship of antenatal sonographic appearance to clinical outcome. 
  • Fetal porencephaly: a review of etiology, diagnosis, and prognosis. 
  • Gestational exposure to chlorpyrifos: apparent protection of the fetus? 
  • Glycemic index and glycemic load are not associated with brain lesions in the elderly. 
  • Guest editorial. 
  • Guideline 1: Minimum technical requirements for performing clinical electroencephalography. 
  • HIV disorders of the brain: pathology and pathogenesis. 
  • HIV-2-associated AIDS in the United States. The first case. 
  • Health-related quality of life in children with inflammatory brain disease. 
  • Hemiballismus: CT and MR findings. 
  • Hepatoxicity with encephalopathy associated with aspirin therapy in rheumatoid arthritis. 
  • Heterogeneity across brain regions and neurotransmitter interactions with nicotinic effects on memory function. 
  • Hydrogels for brain repair after stroke: an emerging treatment option 
  • Hypothalamic insufficiency: the cause of hypopituitarism in sarcoidosis. 
  • Identification of an elaborate complex mediating postsynaptic inhibition. 
  • Imaging genomics. 
  • Impact of encephalopathy on mortality in the sepsis syndrome. The Veterans Administration Systemic Sepsis Cooperative Study Group. 
  • Improved neurodevelopmental outcomes following long-term high-dose oral acyclovir therapy in infants with central nervous system and disseminated herpes simplex disease. 
  • In vivo quantitation of basal ganglia and thalamic degenerative changes in two temporal lobectomy patients with affective disorder. 
  • Incidental findings on brain magnetic resonance imaging of children with sickle cell disease. 
  • Increase in oxidative stress as measured by cerebrospinal fluid lipid peroxidation during treatment for childhood acute lymphoblastic leukemia. 
  • Ineffectiveness of burst suppression therapy in mitigating perioperative cerebrovascular dysfunction. Multicenter Study of Perioperative Ischemia (McSPI) Research Group. 
  • Infantile spasms and encephalopathy without preceding neonatal seizures caused by KCNQ2 R198Q, a gain-of-function variant. 
  • Inhaled carbon monoxide and hyperoxic lung injury in rats. 
  • Inhibitory simple partial (non-convulsive) status epilepticus after intracranial surgery. 
  • Intensive insulin therapy in the neurocritical care setting is associated with poor clinical outcomes. 
  • Intracranial fibromuscular dysplasia in a 5-year-old child. 
  • Intraoperative monitoring of auditory and brain-stem function. 
  • Is early age-related macular degeneration associated with cerebral MRI changes? The Atherosclerosis Risk in Communities study. 
  • Isolated intracranial Rosai-Dorfman disease in a child. 
  • Laser Ablation of Abnormal Neurological Tissue Using Robotic Neuroblate System (LAANTERN): Procedural Safety and Hospitalization. 
  • Late complications after marrow transplantation. 
  • Limbic circuits and neuropsychiatric disorders. Functional anatomy and neuroimaging findings. 
  • Linking variability in brain chemistry and circuit function through multimodal human neuroimaging. 
  • Longitudinal study of neuropsychological functioning in patients on chronic hemodialysis: a preliminary report. 
  • MR and positron emission tomography in the diagnosis of surgically correctable temporal lobe epilepsy. 
  • MR imaging of diseases of the limbic system. 
  • MR perfusion imaging of the brain: techniques and applications. 
  • MRI of brain iron. 
  • Magnetic resonance and diffusion tensor imaging in pediatric white matter diseases. 
  • Magnetic resonance imaging evidence of hippocampal sclerosis in progression: a case report. 
  • Managing depression in geriatric populations. 
  • Maresin 1 attenuates neuroinflammation in a mouse model of perioperative neurocognitive disorders. 
  • Minimal brain dysfunction and methylphenidate. 
  • Missing in Action: African Ancestry Brain Research. 
  • Moderate hypothermia and unilateral selective antegrade cerebral perfusion: a contemporary cerebral protection strategy for aortic arch surgery. 
  • Mood disorders in the medically ill: scientific review and recommendations. 
  • Multiple organ failure after ingestion of pennyroyal oil from herbal tea in two infants. 
  • Mutations in filamin 1 prevent migration of cerebral cortical neurons in human periventricular heterotopia. 
  • National Cancer Institute Workshop statement. Advances in clinical imaging using positron emission tomography, September 14-16, 1988. The Workshop Panel. 
  • Natural history of cerebral complications of coronary artery bypass graft surgery. 
  • Neuro-Behçet's disease: factors hampering proper diagnosis. 
  • Neurobehavioral changes with caudate lesions. 
  • Neurocysticercosis in the United States: 35 cases and a review. 
  • Neurological complications of systemic cancer. 
  • Neuromodulation for mood and memory: from the engineering bench to the patient bedside. 
  • Neuropsychiatric considerations in the use of electroconvulsive therapy. 
  • Neuroradiology case of the day. Multifocal inflammatory leukoencephalopathy due to treatment with 5-fluorouracil and levamisole. 
  • Neurotologic management of intracranial epidermoid tumors. 
  • Neurotoxicity of carbonyl sulfide in F344 rats following inhalation exposure for up to 12 weeks. 
  • New techniques in magnetic resonance imaging. 
  • Non-heme mechanisms for T1 shortening: pathologic, CT, and MR elucidation. 
  • Nonischemic causes of hyperintense signals on diffusion-weighted magnetic resonance images: a pictorial essay. 
  • Occipital Headache in Chronic Lymphocytic Inflammation With Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS). 
  • One-methyl group metabolism in non-ketotic hyperglycinaemia: mildly elevated cerebrospinal fluid homocysteine levels. 
  • Organic bases of depression in the elderly. 
  • Overview of diffusion imaging. 
  • Perfusion MRI: the five most frequently asked technical questions. 
  • Perilesional edema associated with an intracranial calcifying pseudoneoplasm of the neuraxis in a child: case report and review of imaging features. 
  • Periventricular and subcortical nodular heterotopia. A study of 33 patients. 
  • Persistent and fatal central-nervous-system ECHOvirus infections in patients with agammaglobulinemia. 
  • Perspectives from the Society for Pediatric Research. Neonatal encephalopathy clinical trials: developing the future. 
  • Phenobarbital modifies seizure-related brain injury in the developing brain. 
  • Pineal epidermoid cysts. 
  • Porous polyethylene implant for cranioplasty and skull base reconstruction. 
  • Post-traumatic epidermoid cyst: CT appearance. 
  • Prenatal air pollution exposure induces neuroinflammation and predisposes offspring to weight gain in adulthood in a sex-specific manner. 
  • Prenatal genetic diagnosis of Neu-Laxova syndrome. 
  • Prenatal mild ventriculomegaly predicts abnormal development of the neonatal brain. 
  • Proton magnetic resonance spectroscopic imaging in childhood ataxia with diffuse central nervous system hypomyelination. 
  • Proton magnetic resonance spectroscopy and gadolinium-DTPA perfusion imaging of asymptomatic MRI white matter lesions. 
  • Protracted epileptiform encephalopathy: an unusual form of partial complex status epilepticus. 
  • Quantification of contrast in clinical MR brain imaging at high magnetic field. 
  • Radiation Dose Considerations in Emergent Neuroimaging. 
  • Radiologic imaging of AIDS. 
  • Radionuclide emission computed tomography of the head with 99mTc and a scintillation camera. 
  • Region tracking on level-sets methods. 
  • Rethinking the neurosurgical approach to brain disorders from the network neuroscience perspective. 
  • Review of neonatal EEG. 
  • Reye's syndrome treated by peritoneal dialysis. 
  • Reye's syndrome. Possible causes and pathogenetic pathways. 
  • Rickettsial infections and the central nervous system. 
  • Rosai-Dorfman disease presenting with isolated bilateral orbital masses: report of two cases. 
  • S100beta and postcardiac surgery neurological dysfunction: reasons to disregard any link. 
  • Sarcoidosis mimicking glioma: case report and review of intracranial sarcoid mass lesions. 
  • Seizure onset from periventricular nodular heterotopias: depth-electrode study. 
  • Serial MR imaging of pineal cysts: implications for natural history and follow-up. 
  • Sex differences in neurodevelopmental and neurodegenerative disorders: Focus on microglial function and neuroinflammation during development. 
  • Sex differences in neurological outcomes and mortality after cardiac surgery: a society of thoracic surgery national database report. 
  • Shigellosis-associated encephalopathy. 
  • Simulation in Neurosurgery-A Brief Review and Commentary. 
  • Single photon emission computed tomography (SPECT). Part II: Clinical applications. 
  • Smart neuromodulation in movement disorders. 
  • Supporting families in their child's journey with neonatal encephalopathy and therapeutic hypothermia. 
  • Surgical Management of Tumors Involving Meckel's Cave and Cavernous Sinus: Role of an Extended Middle Fossa and Lateral Sphenoidectomy Approach. 
  • Survey of long-term follow-up programs in the United States for survivors of childhood brain tumors. 
  • Symptomatic intracranial pneumatocele from mastoid sinus of spontaneous origin. Case report. 
  • Synchronous neural interactions assessed by magnetoencephalography: a functional biomarker for brain disorders. 
  • System Specific Effects of Therapeutic Hypothermia with Neonatal Encephalopathy: Pearls for Clinicians. 
  • TANGO2: expanding the clinical phenotype and spectrum of pathogenic variants. 
  • The Dynamic Duo: Combining noninvasive brain stimulation with cognitive interventions. 
  • The Haw River syndrome: dentatorubropallidoluysian atrophy (DRPLA) in an African-American family. 
  • The Role of Pediatric Rheumatologists in Autoimmune Brain Disease. 
  • The Sarnat score for neonatal encephalopathy: looking back and moving forward. 
  • The development of brain-machine interface neuroprosthetic devices. 
  • The expanding spectrum of ATP1A3 related disease. 
  • The role of central glucagon-like peptide-1 in mediating the effects of visceral illness: differential effects in rats and mice. 
  • The role of simulation in neurosurgery. 
  • Therapeutic Development of Apolipoprotein E Mimetics for Acute Brain Injury: Augmenting Endogenous Responses to Reduce Secondary Injury. 
  • Total intravenous anesthesia: advantages for intracranial surgery. 
  • Transient choroid plexus cysts and benign asymmetrical ventricles: a case suggesting a possible link: case report. 
  • Tuberous sclerosis complex and epilepsy: prognostic significance of electroencephalography and magnetic resonance imaging. 
  • Typical and atypical MR imaging features of intracranial epidermoid tumors. 
  • Ultrastructural study of Norrie's disease. 
  • Use of graph theory to evaluate brain networks: a clinical tool for a small world? 
  • Uses of nanoparticles for central nervous system imaging and therapy. 
  • Vagus nerve stimulation (VNS): utility in neuropsychiatric disorders. 
  • Vascular morphogenesis: tales of two syndromes. 
  • Visual event-related potentials in progressive supranuclear palsy, corticobasal degeneration, striatonigral degeneration, and Parkinson's disease. 
  • WISC-R verbal and performance IQ discrepancy in an unselected cohort: clinical significance and longitudinal stability. 
  • Where neuroimaging and lesion studies meet. 
  • White matter lesion contrast in fast spin-echo fluid-attenuated inversion recovery imaging: effect of varying effective echo time and echo train length. 
  • Widespread effects of hyperintense lesions on cerebral white matter structure. 
  • [Protein transduction domain peptide mediates delivery to the brain via the blood-brain barrier in Drosophila]. 
  • fMRI activation mapping as a percentage of local excitation: consistent presurgical motor maps without threshold adjustment. 
• 

  Keywords of People

  • Bradford, William Dalton, Professor of Pathology, Pathology
  • Charles, Hal Cecil, Adjunct Associate Professor in the Department of Radiology, Radiology
  • Johnson, G. Allan, Charles E. Putman University Distinguished Professor of Radiology, Biomedical Engineering
  • McLendon, Roger Edwin, Professor of Pathology, Pathology
  • Sampson, John Howard, Robert H., M.D. and Gloria Wilkins Professor of Neurosurgery, in the School of Medicine, Biomedical Engineering
  • Turner, Dennis Alan, Professor of Neurosurgery, Biomedical Engineering