Brain Edema

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  Subject Areas on Research

  • A novel therapeutic derived from apolipoprotein E reduces brain inflammation and improves outcome after closed head injury. 
  • Absolute measurements of water content using magnetic resonance imaging: preliminary findings in an in vivo focal ischemic rat model. 
  • Acute encephalopathy and fatty hepatomegaly. 
  • An Exploratory Analysis of Biomarkers of Perihematomal Edema in the CN-105 in Participants with Acute Supratentorial Intracerebral Hemorrhage (CATCH) Trial. 
  • Apolipoprotein E Mimetic Peptide Increases Cerebral Glucose Uptake by Reducing Blood-Brain Barrier Disruption after Controlled Cortical Impact in Mice: An 18F-Fluorodeoxyglucose PET/CT Study. 
  • Apolipoprotein E affects the central nervous system response to injury and the development of cerebral edema. 
  • Apolipoprotein E modifies neurological outcome by affecting cerebral edema but not hematoma size after intracerebral hemorrhage in humans. 
  • Apolipoprotein E-Mimetic COG1410 Reduces Acute Vasogenic Edema following Traumatic Brain Injury. 
  • ApolipoproteinE mimetic peptides improve outcome after focal ischemia. 
  • Assessment of cerebral microcirculation in a patient with hypertensive encephalopathy using MR perfusion imaging. 
  • Assessment of vasogenic edema in eclampsia using diffusion imaging. 
  • Barbiturate-induced coma to protect against cerebral ischemia and increased intracranial pressure. 
  • Brain ablation in the rat cerebral cortex using a tunable-free electron laser. 
  • Cerebral hemorrhage and edema following brain biopsy in rats: significance of mean arterial blood pressure. 
  • Cerebral infarction in sickle cell trait. 
  • Clinical Reasoning: An 11-year-old girl with focal seizures, fevers, and unilateral, enhancing cortical lesions. 
  • Clinical and Imaging Features of Contrast-Induced Neurotoxicity After Neurointerventional Surgery. 
  • Clinical course and surgical management of massive cerebral infarction. 
  • Cognitive dysfunction after cardiac surgery: revisiting etiology. 
  • Cold-induced brain edema in mice. Involvement of extracellular superoxide dismutase and nitric oxide. 
  • Comparison of patient age with MR imaging features of gangliogliomas. 
  • Decompressive hemicraniectomy in pediatric patients with malignant middle cerebral artery infarction: case series and review of the literature. 
  • Decompressive laparotomy for refractory intracranial hypertension after traumatic brain injury. 
  • Dextromethorphan alters cerebral blood flow and protects against cerebral injury following focal ischemia. 
  • Does midline shift predict postoperative nausea in brain tumor patients undergoing awake craniotomy? A retrospective analysis. 
  • Effects of temperature changes on cerebral biochemistry in spontaneous intracerebral hematoma. 
  • Ethylmalonic aciduria: an organic acidemia with CNS involvement and vasculopathy. 
  • Fatal Cerebral Edema in a Child With COVID-19. 
  • Grey matter edema: the marginal zone of autochthonous virally-induced gliomas. 
  • Head computed tomography interpretation in trauma: a primer. 
  • Hemicraniectomy and durotomy upon deterioration from infarction-related swelling trial: randomized pilot clinical trial. 
  • Hyperammonemia in the ICU. 
  • In vivo quantitation of regional cerebral blood flow in glioma and cerebral infarction: validation of the HIPDm-SPECT method. 
  • Inhibition of Blood-Brain Barrier Disruption by an Apolipoprotein E-Mimetic Peptide Ameliorates Early Brain Injury in Experimental Subarachnoid Hemorrhage. 
  • Intracerebral hemorrhage outcome: apolipoprotein E genotype, hematoma, and edema volumes. 
  • Intravenous immunoglobulin G improves neurobehavioral and histological outcomes after traumatic brain injury in mice. 
  • Letter: Glycerol, cerebral oedema, and diabetes. 
  • Local production of TGF beta1 inhibits cerebral edema, enhances TNF-alpha induced apoptosis and improves survival in a murine glioma model. 
  • MRI-guided laser interstitial thermal therapy in an infant with tuberous sclerosis: technical case report. 
  • Mannitol bolus preferentially shrinks non-infarcted brain in patients with ischemic stroke. 
  • Multiple organ failure after ingestion of pennyroyal oil from herbal tea in two infants. 
  • Multiple sclerosis lesions: relationship between MR enhancement pattern and magnetization transfer effect. 
  • Neuroprotection by N-methyl-D-aspartate antagonists in focal cerebral ischemia is dependent on continued maintenance dosing. 
  • Neuroprotective Pentapeptide, CN-105, Improves Outcomes in Translational Models of Intracerebral Hemorrhage. 
  • Neuroprotective pentapeptide CN-105 improves functional and histological outcomes in a murine model of intracerebral hemorrhage. 
  • Peritumoral brain regions in gliomas and meningiomas: investigation with isotropic diffusion-weighted MR imaging and diffusion-tensor MR imaging. 
  • Poor correlation between perihematomal MRI hyperintensity and brain swelling after intracerebral hemorrhage. 
  • Postasphyxial encephalopathy in term infants. Sonographic demonstration of increased echogenicity of the thalamus and basal ganglia. 
  • Potential implications of Apolipoprotein E in early brain injury after experimental subarachnoid hemorrhage: Involvement in the modulation of blood-brain barrier integrity. 
  • Progesterone Improves Neurobehavioral Outcome in Models of Intracerebral Hemorrhage. 
  • Progression of mass effect after intracerebral hemorrhage. 
  • Protection against focal cerebral ischemia following exposure to a pulsed electromagnetic field. 
  • Psychogenic water intoxication: a fatality. 
  • Quantitative regional brain water measurement with magnetic resonance imaging in a focal ischemia model. 
  • RE: Cerebral air embolism following removal of central venous catheter, published in [Mil Med 2009: 174(8): 878-81]. 
  • Reversible bilateral optic tract edema following pipeline-assisted coiling of a large ophthalmic aneurysm: A case report. 
  • Reversible corpus callosum lesion in legionnaires' disease. 
  • Serial measurements of CT attenuation and specific gravity in experimental cerebral edema. 
  • Sex Differences in Gene and Protein Expression After Intracerebral Hemorrhage in Mice. 
  • Sex-Specific Effects of Progesterone on Early Outcome of Intracerebral Hemorrhage. 
  • Simvastatin and atorvastatin improve behavioral outcome, reduce hippocampal degeneration, and improve cerebral blood flow after experimental traumatic brain injury. 
  • Statins in acute brain injury: getting the cart before the horse. 
  • Strokelore: Intracranial volumes and pressures following cerebral hemorrhage. 
  • Sulfonylurea receptor 1 expression is variable in adult and pediatric brain tumors. 
  • Targeted suppression of claudin-5 decreases cerebral oedema and improves cognitive outcome following traumatic brain injury. 
  • Temporal lobe injury patterns following intensity modulated radiotherapy in a large cohort of nasopharyngeal carcinoma patients. 
  • The apoE-mimetic peptide, COG1410, improves functional recovery in a murine model of intracerebral hemorrhage. 
  • The effects of mannitol on cerebral edema after large hemispheric cerebral infarct. 
  • The electroencephalogram in pediatric practice: its use and abuse. 
  • The pathological role of NLRs and AIM2 inflammasome-mediated pyroptosis in damaged blood-brain barrier after traumatic brain injury. 
  • Thresholds for thermal damage to normal tissues: an update. 
  • Today's Approach to Treating Brain Swelling in the Neuro Intensive Care Unit. 
  • Traumatic brain injury and hemorrhagic shock: evaluation of different resuscitation strategies in a large animal model of combined insults. 
  • Treatment of arterial gas embolism. 
  • Treatment of traumatic brain injury: one size does not fit all. 
  • Valproate-associated carnitine deficiency and malignant cerebral edema in the absence of hepatic failure. 
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  Keywords of People

  • James, Michael Lucas, Associate Professor of Anesthesiology, Anesthesiology
  • Laskowitz, Daniel Todd, Professor of Neurology, Duke Science & Society
  • Muir, Kelly Walton, Associate Professor of Ophthalmology, Ophthalmology, Glaucoma
  • O'Connor, Christopher Michael, Adjunct Professor in the Department of Medicine, Medicine, Clinical Pharmacology
  • Shah, Shreyansh, Assistant Professor of Neurology, Neurology, Neurocritical Care