Bronchoalveolar Lavage Fluid

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  Subject Areas on Research

  • 8-ISO-PGF2alpha production by alveolar macrophages exposed to hyperoxia. 
  • A Genoproteomic Approach to Detect Peptide Markers of Bacterial Respiratory Pathogens. 
  • A robust protocol for regional evaluation of methacholine challenge in mouse models of allergic asthma using hyperpolarized 3He MRI. 
  • Abnormal mouse lung alveolarization caused by Smad3 deficiency is a developmental antecedent of centrilobular emphysema. 
  • Acute eosinophilic pneumonia in a New York City firefighter exposed to World Trade Center dust. 
  • Adsorption of surfactant protein D from human respiratory secretions by carbon nanotubes and polystyrene nanoparticles depends on nanomaterial surface modification and size. 
  • Airway inflammation and responsiveness in prostaglandin H synthase-deficient mice exposed to bacterial lipopolysaccharide. 
  • Allergic lung responses are increased in prostaglandin H synthase-deficient mice. 
  • Alveolar Epithelial Cell-Derived Prostaglandin E2 Serves as a Request Signal for Macrophage Secretion of Suppressor of Cytokine Signaling 3 during Innate Inflammation. 
  • Alveolar macrophages from overweight/obese subjects with asthma demonstrate a proinflammatory phenotype. 
  • Angiogenic growth factors in the pathophysiology of a murine model of acute lung injury. 
  • Anti-neutrophil chemokine preserves alveolar development in hyperoxia-exposed newborn rats. 
  • Asbestos content of bronchoalveolar lavage fluid. A comparison of light and scanning electron microscopic analysis. 
  • Bile acid aspiration associated with lung chemical profile linked to other biomarkers of injury after lung transplantation. 
  • Biological effects of desert dust in respiratory epithelial cells and a murine model. 
  • Brief Glutamine Pretreatment Increases Alveolar Macrophage CD163/Heme Oxygenase-1/p38-MAPK Dephosphorylation Pathway and Decreases Capillary Damage but Not Neutrophil Recruitment in IL-1/LPS-Insufflated Rats. 
  • Bronchial and bronchiolar fibrosis in rats exposed to 2,3-pentanedione vapors: implications for bronchiolitis obliterans in humans. 
  • Bronchoalveolar bile acid and inflammatory markers to identify high-risk lung transplant recipients with reflux and microaspiration. 
  • Bronchoalveolar lavage as a tool to predict, diagnose and understand bronchiolitis obliterans syndrome. 
  • CD19 regulates the development of bleomycin-induced pulmonary fibrosis in a mouse model. 
  • CD4+CD25+Foxp3+ Tregs resolve experimental lung injury in mice and are present in humans with acute lung injury. 
  • CD8+ T-cell alveolitis in familial pulmonary alveolar microlithiasis. 
  • Characterization of the innate immune response to chronic aspiration in a novel rodent model. 
  • Chronic aspiration shifts the immune response from Th1 to Th2 in a murine model of asthma. 
  • Clearance of bile and trypsin in rat lungs following aspiration of human gastric fluid. 
  • Composition of lung lavage in pulmonary alveolar microlithiasis. 
  • Concentrated ambient ultrafine particle exposure induces cardiac changes in young healthy volunteers. 
  • Correlation between sinus and lung cultures in lung transplant patients with cystic fibrosis. 
  • Correlation of intracellular organisms with quantitative endotracheal aspirate. 
  • Correlation of vaccine-elicited systemic and mucosal nonneutralizing antibody activities with reduced acute viremia following intrarectal simian immunodeficiency virus SIVmac251 challenge of rhesus macaques. 
  • Cryptococcus neoformans copper detoxification machinery is critical for fungal virulence. 
  • Cryptococcus neoformans is resistant to surfactant protein A mediated host defense mechanisms. 
  • Cumulative exposure to CD8+ granzyme Bhi T cells is associated with reduced lung function early after lung transplantation. 
  • Cumulative exposure to gamma interferon-dependent chemokines CXCL9 and CXCL10 correlates with worse outcome after lung transplant. 
  • DNA transfection of macaque and murine respiratory tissue is greatly enhanced by use of a nuclease inhibitor. 
  • Detection of Pneumocystis jiroveci in respiratory specimens by four staining methods. 
  • Detection of granulocyte-macrophage colony-stimulating factor in patients with pulmonary alveolar proteinosis. 
  • Development of a novel preclinical model of pneumococcal pneumonia in nonhuman primates. 
  • Development of an Adult Physiologically Based Pharmacokinetic Model of Solithromycin in Plasma and Epithelial Lining Fluid. 
  • Differential Health Effects of Constant versus Intermittent Exposure to Formaldehyde in Mice: Implications for Building Ventilation Strategies. 
  • Differential pulmonary transcriptomic profiles in murine lungs infected with low and highly virulent influenza H3N2 viruses reveal dysregulation of TREM1 signaling, cytokines, and chemokines. 
  • Dynamics of human regulatory T cells in lung lavages of lung transplant recipients. 
  • Early Identification of Acute Lung Injury in a Porcine Model of Hemorrhagic Shock. 
  • Early Immune Response to Acute Gastric Fluid Aspiration in a Rat Model of Lung Transplantation. 
  • Early posttransplant reductions in club cell secretory protein associate with future risk for chronic allograft dysfunction in lung recipients: results from a multicenter study. 
  • Effect of obesity on pulmonary inflammation induced by acute ozone exposure: role of interleukin-6. 
  • Effect of preexposure to ultrafine carbon black on respiratory syncytial virus infection in mice. 
  • Effects of N-acetylcysteine in ozone-induced chronic obstructive pulmonary disease model. 
  • Epithelial clara cell injury occurs in bronchiolitis obliterans syndrome after human lung transplantation. 
  • Euthanasia- and Lavage-mediated Effects on Bronchoalveolar Measures of Lung Injury and Inflammation. 
  • Exogenous leptin enhances markers of airway fibrosis in a mouse model of chronic allergic airways disease. 
  • Exposure to particulate hexavalent chromium exacerbates allergic asthma pathology. 
  • Extracellular superoxide dismutase in the airways of transgenic mice reduces inflammation and attenuates lung toxicity following hyperoxia. 
  • Flow Cytometric Analysis of Myeloid Cells in Human Blood, Bronchoalveolar Lavage, and Lung Tissues. 
  • Full Spectrum of LPS Activation in Alveolar Macrophages of Healthy Volunteers by Whole Transcriptomic Profiling. 
  • Functional heterogeneity of alveolar macrophage population based on expression of CXCL2. 
  • Gene Expression Profiling of Bronchoalveolar Lavage Cells During Aspergillus Colonization of the Lung Allograft. 
  • Gene Expression Profiling of Bronchoalveolar Lavage Cells Preceding a Clinical Diagnosis of Chronic Lung Allograft Dysfunction. 
  • Genetic basis of murine responses to hyperoxia-induced lung injury. 
  • Giant cell interstitial pneumonia in a hard-metal worker. Cytologic, histologic and analytical electron microscopic investigation. 
  • Glutathione depletion in epithelial lining fluid of lung allograft patients. 
  • High-quality CMV-specific CD4+ memory is enriched in the lung allograft and is associated with mucosal viral control. 
  • Highlights from the clinical trials in organ transplantation (CTOT)-20 and CTOT-22 Consortium studies in lung transplant. 
  • Host and environmental factors affect pulmonary responses measured in bronchoalveolar lavage. 
  • Hyaluronan contributes to bronchiolitis obliterans syndrome and stimulates lung allograft rejection through activation of innate immunity. 
  • Hyaluronan fragments contribute to the ozone-primed immune response to lipopolysaccharide. 
  • Hydrogen Sulfide Prevents and Partially Reverses Ozone-Induced Features of Lung Inflammation and Emphysema in Mice. 
  • Identification and Quantitation of Coding Variants and Isoforms of Pulmonary Surfactant Protein A. 
  • Identifying host microRNAs in bronchoalveolar lavage samples from lung transplant recipients infected with Aspergillus. 
  • Immune correlates of protection by mRNA-1273 vaccine against SARS-CoV-2 in nonhuman primates. 
  • Immune reconstitution inflammatory syndrome involving the central nervous system in a patient with HIV infection: a case report and review of literature. 
  • Impact of surfactant protein D, interleukin-5, and eosinophilia on Cryptococcosis. 
  • Innate-like Gene Expression of Lung-Resident Memory CD8+ T Cells during Experimental Human Influenza: A Clinical Study. 
  • Interaction of Bordetella pertussis with mast cells, modulation of cytokine secretion by pertussis toxin. 
  • Intercellular adhesion molecule-1 and L-selectin regulate bleomycin-induced lung fibrosis. 
  • In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies. 
  • Iron accumulates in the lavage and explanted lungs of cystic fibrosis patients. 
  • Iron accumulation in lung allografts after transplantation. 
  • Iron homeostasis and oxidative stress in idiopathic pulmonary alveolar proteinosis: a case-control study. 
  • Iron increases expression of iron-export protein MTP1 in lung cells. 
  • Isolation of mycobacteria in patients with pulmonary alveolar proteinosis. 
  • L-Selectin is required for the development of airway hyperresponsiveness but not airway inflammation in a murine model of asthma. 
  • Lactobacillus rhamnosus GG improves outcome in experimental pseudomonas aeruginosa pneumonia: potential role of regulatory T cells. 
  • Leukocyte-derived IL-10 reduces subepithelial fibrosis associated with chronically inhaled endotoxin. 
  • Long-term exposure of chemokine CXCL10 causes bronchiolitis-like inflammation. 
  • Long-term pulmonary responses of three laboratory rodent species to subchronic inhalation of pigmentary titanium dioxide particles. 
  • Long-term stability at -20 °C of Aspergillus galactomannan in serum and bronchoalveolar lavage specimens. 
  • Low prevalence of Pneumocystis pneumonia (PCP) but high prevalence of pneumocystis dihydropteroate synthase (dhps) gene mutations in HIV-infected persons in Uganda. 
  • Low utilisation of bronchoscopy to assess COVID-19 respiratory infection: a multicenter experience. 
  • Lung compliance measurement in mice. 
  • Lung injury after ozone exposure is iron dependent. 
  • Lung subcellular fractions and surfactant lipid metabolism of rats exposed with DDT or endosulfan intratracheally. 
  • Lung-specific overexpression of CC chemokine ligand (CCL) 2 enhances the host defense to Streptococcus pneumoniae infection in mice: role of the CCL2-CCR2 axis. 
  • Manifestations of pulmonary cryptococcosis in patients with acquired immunodeficiency syndrome. 
  • Mast cell TNF receptors regulate responses to Mycoplasma pneumoniae in surfactant protein A (SP-A)-/- mice. 
  • Maternal exposure to particulate matter increases postnatal ozone-induced airway hyperreactivity in juvenile mice. 
  • Mycobacterium avium pseudo-outbreak associated with an outpatient bronchoscopy clinic: Lessons for reprocessing. 
  • Mycobacterium tuberculosis in lung transplant recipients. 
  • NOS2 regulation of LPS-induced airway inflammation via S-nitrosylation of NF-{kappa}B p65. 
  • Neutrophil extracellular traps are pathogenic in primary graft dysfunction after lung transplantation. 
  • Obese asthmatic patients have decreased surfactant protein A levels: Mechanisms and implications. 
  • Osteopontin expression in particle-induced lung disease. 
  • Overexpression of extracellular superoxide dismutase decreases lung injury after exposure to oil fly ash. 
  • Overexpression of extracellular superoxide dismutase reduces acute radiation induced lung toxicity. 
  • Oxidative stress and inflammation contribute to lung toxicity after a common breast cancer chemotherapy regimen. 
  • Ozone-Induced Models of Airway Hyperreactivity and Epithelial Injury. 
  • Parathyroid hormone-related protein and lung injury after pulmonary thromboendarterectomy. 
  • Patients with asthma demonstrate airway inflammation after exposure to concentrated ambient particulate matter. 
  • Performance of the Bronchoalveolar Lavage Fluid Aspergillus Galactomannan Lateral Flow Assay With Cube Reader for Diagnosis of Invasive Pulmonary Aspergillosis: A Multicenter Cohort Study. 
  • Performance of the Euroimmun Aspergillus Antigen ELISA for the Diagnosis of Invasive Pulmonary Aspergillosis in Bronchoalveolar Lavage Fluid. 
  • Perls' Prussian Blue Stains of Lung Tissue, Bronchoalveolar Lavage, and Sputum. 
  • Plasmalyte as a cause of false-positive results for Aspergillus galactomannan in bronchoalveolar lavage fluid. 
  • Pleural dosimetry and pathobiological responses in rats and hamsters exposed subchronically to MMVF 10a fiberglass. 
  • Pleural effects of indium phosphide in B6C3F1 mice: nonfibrous particulate induced pleural fibrosis. 
  • Point-of-care diagnosis of invasive aspergillosis in non-neutropenic patients: Aspergillus Galactomannan Lateral Flow Assay versus Aspergillus-specific Lateral Flow Device test in bronchoalveolar lavage. 
  • Prevention of influenza-induced lung injury in mice overexpressing extracellular superoxide dismutase. 
  • Proinflammatory cytokines and ARDS pulmonary edema fluid induce CD40 on human mesenchymal stromal cells-A potential mechanism for immune modulation. 
  • Prostaglandin E2 Production and T Cell Function in Mouse Adenovirus Type 1 Infection following Allogeneic Bone Marrow Transplantation. 
  • Protective role of T-bet and Th1 cytokines in pulmonary graft-versus-host disease and peribronchiolar fibrosis. 
  • Proteomic analysis of human bronchoalveolar lavage fluid after subsgemental exposure. 
  • Pseudomonas aeruginosa elastase degrades surfactant proteins A and D. 
  • Pulmonary alveolar proteinosis. 
  • Pulmonary and pleural leukocytes from F344 rats produce elevated levels of fibronectin following inhalation of refractory ceramic fibers. 
  • Pulmonary and pleural responses in Fischer 344 rats following short-term inhalation of a synthetic vitreous fiber. II. Pathobiologic responses. 
  • Pulmonary effects of inhalation of spark-generated silver nanoparticles in Brown-Norway and Sprague-Dawley rats. 
  • Pulmonary histopathology in an experimental model of chronic aspiration is independent of acidity. 
  • Pulmonary nontuberculous mycobacterial infection: radiologic manifestations. 
  • Pulmonary toxicity after exposure to military-relevant heavy metal tungsten alloy particles. 
  • Pulmonary toxicity of induction chemotherapy prior to standard or high-dose chemotherapy with autologous hematopoietic support. 
  • Quantitative proteomics of bronchoalveolar lavage fluid in idiopathic pulmonary fibrosis. 
  • RETRACTED: NAD(P)H:quinone oxidoreductase 1 protects lungs from oxidant-induced emphysema in mice. 
  • RU486 blocks the anti-inflammatory effects of exercise in a murine model of allergen-induced pulmonary inflammation. 
  • Recurrent Henoch-Schönlein Purpura with bullous rash and pulmonary nodules. 
  • Reduced inspiratory flow attenuates IL-8 release and MAPK activation of lung overstretch. 
  • Repetitive Ozone Exposures and Evaluation of Pulmonary Inflammation and Remodeling in Diabetic Mouse Strains. 
  • Reply to "Insufficient demonstration of long-term stability of Aspergillus galactomannan". 
  • Respiratory syncytial virus infection enhances Pseudomonas aeruginosa biofilm growth through dysregulation of nutritional immunity. 
  • Respiratory toxicity of diacetyl in C57BL/6 mice. 
  • Role of complement activation in obliterative bronchiolitis post-lung transplantation. 
  • Role of surface complexed iron in oxidant generation and lung inflammation induced by silicates. 
  • S-nitrosoglutathione reductase: an important regulator in human asthma. 
  • S-nitrosoglutathione supplementation to ovalbumin-sensitized and -challenged mice ameliorates methacholine-induced bronchoconstriction. 
  • SHP-1 as a critical regulator of Mycoplasma pneumoniae-induced inflammation in human asthmatic airway epithelial cells. 
  • Safety and efficacy of weekly oral oltipraz in chronic smokers. 
  • Sensitive and specific detection of the 4B5 antigen in bronchial lavage specimens from patients with primary bronchogenic carcinoma. 
  • Serum Lateral Flow assay with digital reader for the diagnosis of invasive pulmonary aspergillosis: A two-centre mixed cohort study. 
  • Silver-coated endotracheal tubes and incidence of ventilator-associated pneumonia: the NASCENT randomized trial. 
  • Similar but not the same: normobaric and hyperbaric pulmonary oxygen toxicity, the role of nitric oxide. 
  • Soluble alpha2-macroglobulin receptor is increased in endotracheal aspirates from infants and children after cardiopulmonary bypass. 
  • Specialized Pro-Resolving Lipid Mediators Regulate Ozone-Induced Pulmonary and Systemic Inflammation. 
  • Standardisation of the measurement of lung volumes. 
  • Studies on the inhalation toxicology of two fiberglasses and amosite asbestos in the Syrian golden hamster. Part II. Results of chronic exposure. 
  • Studies on the inhalation toxicology of two fiberglasses and amosite asbestos in the syrian golden hamster. Part I. Results of a subchronic study and dose selection for a chronic study. 
  • Surfactant protein A is defective in abrogating inflammation in asthma. 
  • Surgical correction of gastroesophageal reflux in lung transplant patients is associated with decreased effector CD8 cells in lung lavages: a case series. 
  • Survival defects of Cryptococcus neoformans mutants exposed to human cerebrospinal fluid result in attenuated virulence in an experimental model of meningitis. 
  • Synergistic effect of influenza a virus on endotoxin-induced mortality in rat pups: a potential model for sudden infant death syndrome. 
  • Synergistic effects of exposure to concentrated ambient fine pollution particles and nitrogen dioxide in humans. 
  • TRPV4 inhibition counteracts edema and inflammation and improves pulmonary function and oxygen saturation in chemically induced acute lung injury. 
  • Targeting In Vivo Metabolic Vulnerabilities of Th2 and Th17 Cells Reduces Airway Inflammation. 
  • The RNA uridyltransferase Zcchc6 is expressed in macrophages and impacts innate immune responses. 
  • The clinical and environmental determinants of airway transcriptional profiles in allergic asthma. 
  • The role of Toll-like receptor 4 in environmental airway injury in mice. 
  • The spontaneously hypertensive rat: an experimental model of sulfur dioxide-induced airways disease. 
  • The stimulation of cellular phospholipid uptake by surfactant apoproteins. 
  • The use of cylexin (CY-1503) in prevention of reperfusion lung injury in patients undergoing pulmonary thromboendarterectomy. 
  • Traffic-related air pollution induces non-allergic eosinophilic airway inflammation and cough hypersensitivity in guinea-pigs. 
  • Ultrafine carbon black particles enhance respiratory syncytial virus-induced airway reactivity, pulmonary inflammation, and chemokine expression. 
  • Unique cellular and humoral immunogenicity profiles generated by aerosol, intranasal, or parenteral vaccination in rhesus macaques. 
  • Urban airborne particle exposure impairs human lung and blood Mycobacterium tuberculosis immunity. 
  • Use of lung toxicity and lung particle clearance to estimate the maximum tolerated dose (MTD) for a fiber glass chronic inhalation study in the rat. 
  • Usefulness of gene expression profiling of bronchoalveolar lavage cells in acute lung allograft rejection. 
  • Using Interleukin 6 and 8 in Blood and Bronchoalveolar Lavage Fluid to Predict Survival in Hematological Malignancy Patients With Suspected Pulmonary Mold Infection. 
  • Valproic acid mitigates the inflammatory response and prevents acute respiratory distress syndrome in a murine model of Escherichia coli pneumonia at the expense of bacterial clearance. 
  • Value of intraoperative pleural lavage in staging non-small cell lung cancer. 
  • β-Arrestin-2 mediates the proinflammatory effects of proteinase-activated receptor-2 in the airway. 
  • β-arrestin deficiency protects against pulmonary fibrosis in mice and prevents fibroblast invasion of extracellular matrix. 
  • β2-Adrenoceptor agonists are required for development of the asthma phenotype in a murine model. 
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  Keywords of People

  • Driehuys, Bastiaan, Professor of Radiology, Biomedical Engineering
  • Patz Jr., Edward F., James and Alice Chen Distinguished Professor of Radiology, Pathology