Calpain

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  Subject Areas on Research

  • Calcium signals and calpain-dependent necrosis are essential for release of coxsackievirus B from polarized intestinal epithelial cells. 
  • Calpain inhibition prevents sinusoidal endothelial cell apoptosis in the cold ischemic rat liver. 
  • Calpain mediates ischemic injury of the liver through modulation of apoptosis and necrosis. 
  • Calpain-mediated AQP2 proteolysis in inner medullary collecting duct. 
  • Chronic exposure to paclitaxel diminishes phosphoinositide signaling by calpain-mediated neuronal calcium sensor-1 degradation. 
  • Constitutive proteasome-mediated turnover of Bfl-1/A1 and its processing in response to TNF receptor activation in FL5.12 pro-B cells convert it into a prodeath factor. 
  • Diagnosis of limb-girdle muscular dystrophy 2A by immunohistochemical techniques. 
  • Epigenome-Wide Association Study for All-Cause Mortality in a Cardiovascular Cohort Identifies Differential Methylation in Castor Zinc Finger 1 (CASZ1). 
  • Evidence that calpains and elastase do not produce the von Willebrand factor fragments present in normal plasma and IIA von Willebrand disease. 
  • Evidence that non-caspase proteases are required for chromatin degradation during apoptosis. 
  • In vitro proteolysis of brain spectrin by calpain I inhibits association of spectrin with ankyrin-independent membrane binding site(s). 
  • Regulatory domains of erythrocyte ankyrin. 
  • Release of intracellular calcium stores facilitates coxsackievirus entry into polarized endothelial cells. 
  • TNF-induced necroptosis and PARP-1-mediated necrosis represent distinct routes to programmed necrotic cell death. 
  • The Calpain Gene is Correlated With Metal-on-Metal Hip Replacement Failures. 
  • The role of proteolytic cellular systems in trabecular meshwork homeostasis.