Capillary Permeability

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  Subject Areas on Research

  • Abl family kinases regulate endothelial barrier function in vitro and in mice. 
  • Acute local subcutaneous VEGF165 injection for augmentation of skin flap viability: efficacy and mechanism. 
  • Adenosine-induced modulation of excitatory amino acid transport across isolated brain arterioles. 
  • Analytic solution to steady-state radial diffusion of a substrate with first-order reaction kinetics in the tissue of a Krogh's cylinder. 
  • Angiogenic growth factors in the pathophysiology of a murine model of acute lung injury. 
  • Anti-inflammatory and vasoprotective activity of a retroviral-derived peptide, homologous to human endogenous retroviruses: endothelial cell effects. 
  • Application of a Novel Murine Ear Vein Model to Evaluate the Effects of a Vascular Radioprotectant on Radiation-Induced Vascular Permeability and Leukocyte Adhesion. 
  • Assessing cardiac injury in mice with dual energy-microCT, 4D-microCT, and microSPECT imaging after partial heart irradiation. 
  • Augmentation of transvascular transport of macromolecules and nanoparticles in tumors using vascular endothelial growth factor. 
  • Bevacizumab-induced alterations in vascular permeability and drug delivery: a novel approach to augment regional chemotherapy for in-transit melanoma. 
  • Blockade of tissue factor-factor X binding attenuates sepsis-induced respiratory and renal failure. 
  • Blood-brain barrier dysfunction after primary blast injury in vitro. 
  • Cell-free hemoglobin promotes primary graft dysfunction through oxidative lung endothelial injury. 
  • Cerebral blood flow, blood volume, and vascular permeability of cerebral glioma assessed with dynamic CT perfusion imaging. 
  • Characterization of diffusing capacity and perfusion of the rat lung in a lipopolysaccaride disease model using hyperpolarized 129Xe. 
  • Characterization of sites with elevated LDL permeability at intercostal, celiac, and iliac branches of the normal rabbit aorta. 
  • Characterization of the effect of hyperthermia on nanoparticle extravasation from tumor vasculature. 
  • Chronic inflammatory pain leads to increased blood-brain barrier permeability and tight junction protein alterations. 
  • Comparison of permeability in high-grade and low-grade brain tumors using dynamic susceptibility contrast MR imaging. 
  • Competitive apnea and its effect on the human brain: focus on the redox regulation of blood-brain barrier permeability and neuronal-parenchymal integrity. 
  • Concurrent measurements of blood flow and transcapillary transport in xenotransplanted human gliomas in immunosuppressed rats. 
  • Contributions of mast cells and vasoactive products, leukotrienes and chymase, to dengue virus-induced vascular leakage. 
  • Correlation of relative permeability and relative cerebral blood volume in high-grade cerebral neoplasms. 
  • Decreased blood-brain barrier permeability to fluorescein in streptozotocin-treated rats. 
  • Dengue vascular leakage is augmented by mast cell degranulation mediated by immunoglobulin Fcγ receptors. 
  • Dengue virus-elicited tryptase induces endothelial permeability and shock. 
  • Derangement of the endothelial glycocalyx in sepsis. 
  • Diffusing capacity of the lung for carbon monoxide. 
  • Dual-energy micro-computed tomography imaging of radiation-induced vascular changes in primary mouse sarcomas. 
  • Effect of U74006F (Tirilazad Mesylate) in rabbit eyes after argon laser trabeculoplasty. 
  • Effect of hypercholesterolemia on transendothelial EBD-albumin permeability and lipid accumulation in porcine iliac arteries. 
  • Endothelial cell function and endothelial-related disorders following haematopoietic cell transplantation. 
  • Endothelial cell junctions and the regulation of vascular permeability and leukocyte transmigration. 
  • Endotoxin-induced uveitis in the rat: observations on altered vascular permeability, clinical findings, and histology. 
  • Engineering the tissue which encapsulates subcutaneous implants. II. Plasma-tissue exchange properties. 
  • Fluorescein Angiographic Characteristics of Macular Edema During Infancy. 
  • Further characterization of a factor from endotoxin-treated serum which releases histamine and heparin from mast cells. 
  • Genetic variation in surfactant protein-A2 alters responses to ozone. 
  • Heterogeneity and vascular permeability of breast cancer brain metastases. 
  • Hydrogels with precisely controlled integrin activation dictate vascular patterning and permeability 
  • Hyperthermia enables tumor-specific nanoparticle delivery: effect of particle size. 
  • Hypoxia-induced inhibin promotes tumor growth and vascular permeability in ovarian cancers. 
  • IDENTIFICATION OF FLUID ON OPTICAL COHERENCE TOMOGRAPHY BY TREATING OPHTHALMOLOGISTS VERSUS A READING CENTER IN THE COMPARISON OF AGE-RELATED MACULAR DEGENERATION TREATMENTS TRIALS. 
  • Illuminating Lung Inflammation at the Alveolar Capillary Interface. 
  • Impairment of the blood-nerve and blood-brain barriers in apolipoprotein e knockout mice. 
  • Implications of Increase in Vascular Permeability in Tumors by VEGF: A Commentary on the Pioneering Work of Harold Dvorak. 
  • Increased microvascular permeability contributes to preferential accumulation of Stealth liposomes in tumor tissue. 
  • Infection-Induced Vascular Permeability Aids Mycobacterial Growth. 
  • Inhibition of infection-induced vascular permeability modulates host leukocyte recruitment to Mycobacterium marinum granulomas in zebrafish. 
  • Interaction of wall shear stress magnitude and gradient in the prediction of arterial macromolecular permeability 
  • Interendothelial claudin-5 expression depends on cerebral endothelial cell-matrix adhesion by β(1)-integrins. 
  • Lumbar Myeloid Cell Trafficking into Locomotor Networks after Thoracic Spinal Cord Injury. 
  • Magnetic resonance imaging applications in the evaluation of tumor angiogenesis. 
  • Male germ cells and photoreceptors, both dependent on close cell-cell interactions, degenerate upon ClC-2 Cl(-) channel disruption. 
  • Measurement of material extravasation in microvascular networks using fluorescence video-microscopy. 
  • Mechanisms associated with tumor vascular shut-down induced by combretastatin A-4 phosphate: intravital microscopy and measurement of vascular permeability. 
  • Mediators of pulmonary injury induced by inhalation of bacterial endotoxin. 
  • MiR-21 alleviates secondary blood-brain barrier damage after traumatic brain injury in rats. 
  • Microvascular abnormalities in virally-induced canine brain tumors. Structural bases for altered blood-brain barrier function. 
  • Microvascular permeability and interstitial penetration of sterically stabilized (stealth) liposomes in a human tumor xenograft. 
  • Microvascular permeability of albumin, vascular surface area, and vascular volume measured in human adenocarcinoma LS174T using dorsal chamber in SCID mice. 
  • Modulation of cerebral microvascular permeability by endothelial nicotinic acetylcholine receptors. 
  • Modulation of cytokines and chemokines, limited pulmonary vascular bed permeability, and prevention of septicemia and death with ceftriaxone and interleukin-10 in pneumococcal pneumonia. 
  • Myocardial function and transmural blood flow during coronary venous retroperfusion in pigs. 
  • Negative-feedback loop attenuates hydrostatic lung edema via a cGMP-dependent regulation of transient receptor potential vanilloid 4. 
  • Nicotine and cotinine modulate cerebral microvascular permeability and protein expression of ZO-1 through nicotinic acetylcholine receptors expressed on brain endothelial cells. 
  • Nicotine increases in vivo blood-brain barrier permeability and alters cerebral microvascular tight junction protein distribution. 
  • Ocular albumin fluorophotometric quantitation of endotoxin-induced vascular permeability. 
  • Oncostatin M enhances CCL21 expression by microvascular endothelial cells and increases the efficiency of dendritic cell trafficking to lymph nodes. 
  • Outcomes in Eyes with Retinal Angiomatous Proliferation in the Comparison of Age-Related Macular Degeneration Treatments Trials (CATT). 
  • Oxidized lipid-mediated alterations in proteoglycan metabolism in cultured pulmonary endothelial cells. 
  • Oxygen transport in resting and contracting hamster cremaster muscles: experimental and theoretical microvascular studies. 
  • Pathogenesis of pneumococcal pneumonia in cyclophosphamide-induced leukopenia in mice. 
  • Pathophysiology of the blood-brain barrier: animal models and methods. 
  • Perfusion of single tumor microvessels: application to vascular permeability measurement. 
  • Peripheral retinal vascular leakage demonstrated by ultra-widefield fluorescein angiography in preeclampsia with HELLP syndrome. 
  • Permeability of different experimental brain tumor models to horseradish peroxidase. 
  • Pharmacokinetics and safety of TP10, soluble complement receptor 1, in infants undergoing cardiopulmonary bypass. 
  • Potential antiglioma activity of 9-hydroxy-2-N-methylellipticine as determined by pharmacological and human tumor clonogenic cell studies. 
  • Quantitation and physiological characterization of angiogenic vessels in mice: effect of basic fibroblast growth factor, vascular endothelial growth factor/vascular permeability factor, and host microenvironment. 
  • Recombinant tissue plasminogen activator injected into the vitreous cavity may penetrate the retinal veins of a porcine model of vascular occlusion. 
  • Regional blood-to-tissue transport in avian sarcoma virus (ASV)-induced brain tumors. 
  • Regional localization of a glioma-associated antigen defined by monoclonal antibody 81C6 in vivo: kinetics and implications for diagnosis and therapy. 
  • Regional measurements of blood-to-tissue transport in experimental RG-2 rat gliomas. 
  • Relation between non-uniform hemodynamics and sites of altered permeability and lesion growth at the rabbit aorto-celiac junction. 
  • Repeated primary blast injury causes delayed recovery, but not additive disruption, in an in vitro blood-brain barrier model. 
  • Retinal microvascular abnormalities and age-related hearing loss: the Blue Mountains hearing study. 
  • Role for endotoxin and complement in periodontal tissue destruction. 
  • Role of Transient Receptor Potential Vanilloid 4 in Neutrophil Activation and Acute Lung Injury. 
  • Role of neutrophils in breakdown of the blood-retinal barrier following intravitreal injection of platelet-activating factor. 
  • Role of nitric oxide in tumor microcirculation. Blood flow, vascular permeability, and leukocyte-endothelial interactions. 
  • Sensitization of Vascular Endothelial Cells to Ionizing Radiation Promotes the Development of Delayed Intestinal Injury in Mice. 
  • Severity of Plasma Leakage Is Associated With High Levels of Interferon γ-Inducible Protein 10, Hepatocyte Growth Factor, Matrix Metalloproteinase 2 (MMP-2), and MMP-9 During Dengue Virus Infection. 
  • TRPV4 initiates the acute calcium-dependent permeability increase during ventilator-induced lung injury in isolated mouse lungs. 
  • Targeting N-cadherin increases vascular permeability and differentially activates AKT in melanoma. 
  • Th1-Polarized, Dengue Virus-Activated Human Mast Cells Induce Endothelial Transcriptional Activation and Permeability. 
  • The cellular basis of traumatic bleeding. 
  • The role of carrier size in the pharmacodynamics of antisense and siRNA oligonucleotides. 
  • Thrombospondin-1 modulates vascular endothelial growth factor activity at the receptor level. 
  • Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody. 
  • Transvascular drug delivery in solid tumors. 
  • Tumor microvascular permeability is a key determinant for antivascular effects of doxorubicin encapsulated in a temperature sensitive liposome. 
  • Tumor vascular permeability to a nanoprobe correlates to tumor-specific expression levels of angiogenic markers. 
  • Tumor vascular permeability, accumulation, and penetration of macromolecular drug carriers. 
  • Vascular permeability and microcirculation of gliomas and mammary carcinomas transplanted in rat and mouse cranial windows. 
  • Vascular permeability in a human tumor xenograft: molecular size dependence and cutoff size. 
  • Vascular permeability in a human tumour xenograft: molecular charge dependence. 
  • p53 functions in endothelial cells to prevent radiation-induced myocardial injury in mice. 
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  Keywords of People

  • Badea, Cristian Tudorel, Professor in Radiology, Biomedical Engineering
  • Cianciolo, George James, Associate Professor Emeritus of Pathology, Pathology
  • Driehuys, Bastiaan, Professor of Radiology, Biomedical Engineering
  • Stinnett, Sandra Sue, Associate Professor of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics
  • Sunday, Mary Elizabeth Anne, Professor of Pathology, Cell Biology