Carboxylic Ester Hydrolases

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  Subject Areas on Research

  • A gain-of-function mutation in a plant disease resistance gene leads to constitutive activation of downstream signal transduction pathways in suppressor of npr1-1, constitutive 1. 
  • Assessment of the delayed neurotoxicity of tributyl phosphate, tributoxyethyl phosphate, and dibutylphenyl phosphate. 
  • Axoplasmic transport and turnaround of neurotoxic esterase in hen sciatic nerve. 
  • Chloroacetate esterase positivity in acute lymphoblastic leukemia. 
  • Cloning of the esterase D gene: a polymorphic gene probe closely linked to the retinoblastoma locus on chromosome 13. 
  • Comparison of fetal, newborn, and adult wound healing by histologic, enzyme-histochemical, and hydroxyproline determinations. 
  • Constitutive salicylic acid-dependent signaling in cpr1 and cpr6 mutants requires PAD4. 
  • Differential effects of triphenylphosphite and diisopropyl phosphorofluoridate on catecholamine secretion from bovine adrenomedullary chromaffin cells. 
  • Engineering a biospecific communication pathway between cells and electrodes. 
  • Gradated assembly of multiple proteins into supramolecular nanomaterials. 
  • In vivo inhibition of PC-3 human androgen-independent prostate cancer by a targeted cytotoxic bombesin analogue, AN-215. 
  • Individualization of treatments with drugs metabolized by CES1: combining genetics and metabolomics. 
  • Joint acute toxicity of esfenvalerate and diazinon to larval fathead minnows (Pimephales promelas). 
  • Kinetics of substrate hydrolysis and inhibition by mipafox of paraoxon-preinhibited hen brain esterase activity. 
  • Liquid lung ventilation reduces neutrophil sequestration in a neonatal swine model of cardiopulmonary bypass. 
  • Nomenclature for alleles of the human carboxylesterase 1 gene. 
  • Novel breast cancer biomarkers identified by integrative proteomic and gene expression mapping. 
  • Paraoxon reversibly inhibits neurotoxic esterase. 
  • Predicting urine culture results by dipstick testing and phase contrast microscopy. 
  • Synthetic cannabimimetic agents metabolized by carboxylesterases. 
  • Target size of neurotoxic esterase and acetylcholinesterase as determined by radiation inactivation. 
  • The correlation between the recovery rate of neurotoxic esterase activity and sensitivity to organophosphorus-induced delayed neurotoxicity. 
  • The effects of tri-o-cresyl phosphate and metabolites on rat Sertoli cell function in primary culture. 
  • The functional G143E variant of carboxylesterase 1 is associated with increased clopidogrel active metabolite levels and greater clopidogrel response. 
  • The role of low levels of juvenile hormone esterase in the metamorphosis of Manduca sexta. 
  • The role of pharmacokinetics and metabolism in species sensitivity to neurotoxic agents. 
  • Triphenyl phosphite neurotoxicity in the hen: inhibition of neurotoxic esterase and of prophylaxis by phenylmethylsulfonyl fluoride. 
  • Vapor detection and discrimination with a panel of odorant receptors. 
  • Variation between three strains of rat: inhibition of neurotoxic esterase and acetylcholinesterase by tri-o-cresyl phosphate.