Carcinoma in Situ

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  Subject Areas on Research

  • A Pilot Study of a Screening Program for Human Papillomavirus-Related Squamous Intraepithelial Lesion and Malignancy in Gynecologic Oncology Patients. 
  • A SAGE (serial analysis of gene expression) view of breast tumor progression. 
  • A high association of oncogenic human papillomaviruses with carcinomas of the female urethra: polymerase chain reaction-based analysis of multiple histological types. 
  • A histologic review of vulvar inflammatory dermatoses and intraepithelial neoplasm. 
  • Accuracy of intraoperative gross examination of surgical margin status in women undergoing partial mastectomy for breast malignancy. 
  • Androgen-independent prostate cancer progression in the TRAMP model. 
  • Antidepressant medications and their association with invasive breast cancer and carcinoma in situ of the breast. 
  • Association between non-steroidal anti-inflammatory drugs (NSAIDs) and invasive breast cancer and carcinoma in situ of the breast. 
  • Association of breast cancer with the finding of atypical ductal hyperplasia at core breast biopsy. 
  • Basaloid-squamous carcinoma of the tongue, hypopharynx, and larynx: report of 10 cases. 
  • Benign endometrial hyperplasia sequence and endometrial intraepithelial neoplasia. 
  • Bilaterality and recurrence rates for lobular breast cancer: considerations for treatment. 
  • Breast cancer in patients treated for Hodgkin's disease: clinical and pathological analysis of 76 cases in 63 patients. 
  • Breast cancer: noninvasive and special situations. 
  • Clinical application of array-based comparative genomic hybridization to define the relationship between multiple synchronous tumors. 
  • Clonality of lobular carcinoma in situ and synchronous invasive lobular carcinoma. 
  • Coital risk factors for cervical cancer. Sexual activity among white middle class women. 
  • Combined p53 and retinoblastoma protein detection identifies persistent and regressive cervical high-grade squamous intraepithelial lesions. 
  • Conjunctival intraepithelial neoplasia. 
  • Contemporary management of ductal carcinoma in situ and lobular carcinoma in situ. 
  • Critical review of radical cystectomy and indicators of prognosis. 
  • Cytologic evaluation of lumpectomy margins in patients with ductal carcinoma in situ: clinical outcome. 
  • Cytological evaluation correlates poorly with histological diagnosis of vulvar neoplasias. 
  • Detection of primary breast carcinoma with a dedicated, large-field-of-view FDG PET mammography device: initial experience. 
  • Diagnosis and management of conjunctival and corneal intraepithelial neoplasia using ultra high-resolution optical coherence tomography. 
  • Diagnosis of breast cancer using diffuse reflectance spectroscopy: Comparison of a Monte Carlo versus partial least squares analysis based feature extraction technique. 
  • Differentiated Vulvar Intraepithelial Neoplasia: What Criteria Do We Use in Practice? 
  • Ductal Carcinoma In Situ in Pregnant Women. 
  • Ductal Carcinoma in Situ: State-of-the-Art Review. 
  • Ductal carcinoma in situ: atypical mammographic appearances. 
  • Dysplasia at the surgical margin is associated with recurrence after resection of non-invasive intraductal papillary mucinous neoplasms. 
  • Endoscopic brush cytology of the upper urinary tract. Evaluation of its efficacy and potential limitations in diagnosis. 
  • Estrogen receptor alpha (ESR1) mutant A908G is not a common feature in benign and malignant proliferations of the breast. 
  • Evaluation of the Fluorescence In Situ Hybridization Test to Predict Recurrence and/or Progression of Disease after bacillus Calmette-Guérin for Primary High Grade Nonmuscle Invasive Bladder Cancer: Results from a Prospective Multicenter Trial. 
  • Evidence of a Monoclonal Origin for Bilateral Serous Tubal Intraepithelial Neoplasia. 
  • Expression of epidermal growth factor receptor and HER-2/neu in normal and neoplastic cervix, vulva, and vagina. 
  • Flow cytometric DNA analysis of excised breast lesions: use of fresh tissue needle aspirates obtained under guidance with mammography of the specimen. 
  • Four year efficacy of prophylactic human papillomavirus quadrivalent vaccine against low grade cervical, vulvar, and vaginal intraepithelial neoplasia and anogenital warts: randomised controlled trial. 
  • From Dog's Breakfast to Michelin Guide: Post-bacillus Calmette-Guérin Trials in Non-muscle-invasive Bladder Cancer. 
  • Gamma-ray-induced mutagen sensitivity and risk of sporadic breast cancer in young women: a case-control study. 
  • Genetic and phenotypic characteristics of pleomorphic lobular carcinoma in situ of the breast. 
  • Genomic alterations and phenotype of large compared to small high-grade ductal carcinoma in situ. 
  • Guidelines for sentinel node biopsy and lymphatic mapping of patients with breast cancer. 
  • Human papillomavirus in early laryngeal carcinoma. 
  • Hypermethylation of the breast cancer-associated gene 1 promoter does not predict cytologic atypia or correlate with surrogate end points of breast cancer risk. 
  • Imaging-guided core needle biopsy of papillary lesions of the breast. 
  • In situ assessment of intraepithelial neoplasia in hamster trachea epithelium using angle-resolved low-coherence interferometry. 
  • Incidental minimal atypical lobular hyperplasia on core needle biopsy: correlation with findings on follow-up excision. 
  • Incidentally discovered pancreatic intraepithelial neoplasia: what is its clinical significance? 
  • Increased incidence of cervical and vaginal dysplasia in 3,980 diethylstilbestrol-exposed young women. Experience of the National Collaborative Diethylstilbestrol Adenosis Project. 
  • Intracavitary mitomycin-C in the treatment of superficial urothelial tumors: a preliminary report. 
  • Intravesical nadofaragene firadenovec gene therapy for BCG-unresponsive non-muscle-invasive bladder cancer: a single-arm, open-label, repeat-dose clinical trial. 
  • Is radiation indicated in patients with ductal carcinoma in situ and close or positive mastectomy margins? 
  • KRAS2 mutations in human pancreatic acinar-ductal metaplastic lesions are limited to those with PanIN: implications for the human pancreatic cancer cell of origin. 
  • Keratosis reduces sensitivity of anal cytology in detecting anal intraepithelial neoplasia. 
  • Lobular carcinoma in situ: observation without surgery as an appropriate therapy. 
  • Loss of cyclin D2 expression in the majority of breast cancers is associated with promoter hypermethylation. 
  • MR imaging of ductal carcinoma in situ. 
  • Maintenance of DNA content and erbB-2 alterations in intraductal and invasive phases of mammary cancer. 
  • Maintenance of p53 alterations throughout breast cancer progression. 
  • Management of ductal carcinoma in situ. 
  • Median nerve injury associated with radial forearm free flap harvest. 
  • Microscopic localization of calcifications in and around breast carcinoma: a cautionary note for needle core biopsies. 
  • Ocular and Periocular Tumors in Xeroderma Pigmentosum: A Study of 120 Asian Indian Patients. 
  • Omission of Radiation in Conservative Treatment for Breast Cancer: Opportunity for De-escalation of Care. 
  • Outcomes after total skin-sparing mastectomy and immediate reconstruction in 657 breasts. 
  • Overexpression of human carcinoma-associated antigen in esophageal adenocarcinoma and its precursor lesions. 
  • PD-L1 (B7-H1) expression by urothelial carcinoma of the bladder and BCG-induced granulomata: associations with localized stage progression. 
  • Pancreatic intraepithelial neoplasia and histological changes in non-neoplastic pancreas associated with neoadjuvant therapy in patients with pancreatic ductal adenocarcinoma. 
  • Papillary carcinoma of the breast: imaging findings. 
  • Pathologic Evaluation and Reporting of Intraductal Papillary Mucinous Neoplasms of the Pancreas and Other Tumoral Intraepithelial Neoplasms of Pancreatobiliary Tract: Recommendations of Verona Consensus Meeting. 
  • Pathologic considerations in the high-risk breast patient. 
  • Pathology of colposcopic findings in 2635 diethylstilbestrol-exposed young women. 
  • Pathology of prenatal diethylstilbestrol exposure. 
  • Perilesional and topical interferon alfa-2b for conjunctival and corneal neoplasia. 
  • Positron emission tomography in the pretreatment evaluation and follow-up of non-small cell lung cancer patients treated with radiotherapy: preliminary findings. 
  • Prediction of Occult Invasive Disease in Ductal Carcinoma in Situ Using Deep Learning Features. 
  • Prediction of Upstaging in Ductal Carcinoma in Situ Based on Mammographic Radiomic Features. 
  • Prevalence of dysplasia and cancer of the cervix in a nationwide, planned parenthood population. 
  • Primary chondroid melanoma. 
  • Primary high-grade neuroendocrine carcinoma of the esophagus: a clinicopathologic and immunohistochemical study of 42 resection cases. 
  • Psychometric properties of a tool for measuring hormone-related symptoms in breast cancer survivors. 
  • Risk for Upgrade to Malignancy After Breast Core Needle Biopsy Diagnosis of Lobular Neoplasia: A Systematic Review and Meta-Analysis. 
  • Role of hormones including diethylstibestrol (DES) in the pathogenesis of cervical and vaginal intraepithelial neoplasia. 
  • Seminal vesicle intraepithelial involvement by prostate cancer: putative mechanism and clinicopathological significance. 
  • Society of Surgical Oncology-American Society for Radiation Oncology consensus guideline on margins for breast-conserving surgery with whole-breast irradiation in stages I and II invasive breast cancer. 
  • Squamous cell carcinoma of the conjunctiva. Value of exfoliative cytology in diagnosis. 
  • Squamous cell dysplasia and carcinoma in situ of the cervix and vagina after prenatal exposure to diethylstilbestrol. 
  • Squamous cell neoplasia controversy in the female exposed to diethylstilbestrol. 
  • TSPO-targeted PET and Optical Probes for the Detection and Localization of Premalignant and Malignant Pancreatic Lesions. 
  • Telomerase activity in ductal carcinoma in situ and invasive breast cancer. 
  • Telomeres are shortened in acinar-to-ductal metaplasia lesions associated with pancreatic intraepithelial neoplasia but not in isolated acinar-to-ductal metaplasias. 
  • The COMET (Comparison of Operative versus Monitoring and Endocrine Therapy) trial: a phase III randomised controlled clinical trial for low-risk ductal carcinoma in situ (DCIS). 
  • The Influence of Body Mass Index on the Histopathology and Outcomes of Patients Diagnosed with Atypical Breast Lesions. 
  • The Landmark Series-Ductal Carcinoma in Situ: The Evolution of Treatment. 
  • The anatomical distribution of colorectal polyps at colonoscopy. 
  • The anatomy of missed breast cancers. 
  • The impact of lobular histology on breast cancer treatment. 
  • The molecular genetics and morphometry-based endometrial intraepithelial neoplasia classification system predicts disease progression in endometrial hyperplasia more accurately than the 1994 World Health Organization classification system. 
  • The need for epidemiologic studies of in-situ carcinoma of the breast. 
  • Treatment of superficial carcinoma of the bladder. 
  • Vaginal epithelial changes in young women enrolled in the National Cooperative Diethylstilbestrol Adenosis (DESAD) project. 
  • p16 Improves interobserver agreement in diagnosis of anal intraepithelial neoplasia. 
  • p16 Inactivation in pancreatic intraepithelial neoplasias (PanINs) arising in patients with chronic pancreatitis. 
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  Keywords of People

  • Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Palmer, Gregory M., Associate Professor of Radiation Oncology, Radiation Oncology