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Subject Areas on Research
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"Heparin-free" cardiopulmonary bypass: first reported use of heparinoid (Org 10172) to provide anticoagulation for cardiopulmonary bypass.
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A Multicenter Pilot Study Assessing Regional Cerebral Oxygen Desaturation Frequency During Cardiopulmonary Bypass and Responsiveness to an Intervention Algorithm.
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A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of Preoperative Antithrombin Supplementation in Patients at Risk for Antithrombin Deficiency After Cardiac Surgery.
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A bolus dose of 1.5 mg/kg amrinone effectively improves low cardiac output state following separation from cardiopulmonary bypass in cardiac surgical patients.
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A case series of recombinant platelet factor 4 for heparin reversal after cardiopulmonary bypass.
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A change in anticoagulation monitoring improves safety, reduces transfusion, and reduces costs in infants on cardiopulmonary bypass.
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A clinical comparison of mitral valve repair versus valve replacement in ischemic mitral regurgitation.
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A comparison of bivalirudin to heparin with protamine reversal in patients undergoing cardiac surgery with cardiopulmonary bypass: the EVOLUTION-ON study.
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A diagnosis of heparin-induced thrombocytopenia with combined clinical and laboratory methods in cardiothoracic surgical intensive care unit patients.
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A method for perfusion of the leg during cardiopulmonary bypass via femoral cannulation.
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A novel antidote-controlled anticoagulant reduces thrombin generation and inflammation and improves cardiac function in cardiopulmonary bypass surgery.
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A novel survival model of cardioplegic arrest and cardiopulmonary bypass in rats: a methodology paper.
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A phase 2 prospective, randomized, double-blind trial comparing the effects of tranexamic acid with ecallantide on blood loss from high-risk cardiac surgery with cardiopulmonary bypass (CONSERV-2 Trial).
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A phase II multicenter double-blind placebo-controlled study of ethyl pyruvate in high-risk patients undergoing cardiac surgery with cardiopulmonary bypass.
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A phase II, double-blind, placebo-controlled, ascending-dose study of Eritoran (E5564), a lipid A antagonist, in patients undergoing cardiac surgery with cardiopulmonary bypass.
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A phase III, double-blind, placebo-controlled, multicenter study on the efficacy of recombinant human antithrombin in heparin-resistant patients scheduled to undergo cardiac surgery necessitating cardiopulmonary bypass.
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A systematic review of the evidence supporting post-operative antithrombotic use following cardiopulmonary bypass in children with CHD.
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A systematic review of the evidence supporting post-operative diuretic use following cardiopulmonary bypass in children with Congenital Heart Disease.
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A systematic review of the evidence supporting post-operative medication use in congenital heart disease.
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Acadesine inhibits neutrophil CD11b up-regulation in vitro and during in vivo cardiopulmonary bypass.
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Activated Coagulation Time and Hepcon Protamine Titration Device to Manage Unfractionated Heparin During Cardiopulmonary Bypass in a Hemophilia A Patient on Emicizumab.
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Activated clotting time systems vary in precision and bias and are not interchangeable when following heparin management protocols during cardiopulmonary bypass.
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Acute depression of myocardial beta-adrenergic receptor signaling during cardiopulmonary bypass: impairment of the adenylyl cyclase moiety. Duke Heart Center Perioperative Desensitization Group.
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Acute functional consequences of left ventriculotomy.
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Acute myocardial beta-adrenergic receptor dysfunction after cardiopulmonary bypass in patients with cardiac valve disease. Duke Heart Center Perioperative Desensitization Group.
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Acute renal failure after cardiopulmonary bypass in related to decreased serum ferritin levels.
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Acute renal injury and lowest hematocrit during cardiopulmonary bypass: not only a matter of cellular hypoxemia.
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Adenoviral gene transfer to the heart during cardiopulmonary bypass: effect of myocardial protection technique on transgene expression.
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Adrenal cortical carcinoma with vena cava tumor thrombus requiring cardiopulmonary bypass for resection.
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Alkaline Phosphatase Activity and Endotoxemia After Infant Cardiothoracic Surgery.
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Alkaline Phosphatase in Infant Cardiopulmonary Bypass: Kinetics and Relationship to Organ Injury and Major Cardiovascular Events.
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Alkaline Phosphatase, Soluble Extracellular Adenine Nucleotides, and Adenosine Production after Infant Cardiopulmonary Bypass.
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Amrinone: its effect on vascular resistance and capacitance in human subjects.
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An Alternative Technique for Hemiarch Replacement Without Using Deep Hypothermic Circulatory Arrest.
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An evidence-based review of the use of vasoactive and inotropic medications in post-operative paediatric patients after cardiac surgery with cardiopulmonary bypass from 2000 to 2020.
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An ultrafiltration technique for directly reinfusing residual cardiopulmonary bypass blood.
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Analyses of coronary graft patency after aprotinin use: results from the International Multicenter Aprotinin Graft Patency Experience (IMAGE) trial.
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Andexanet Alfa Use in Patients Requiring Cardiopulmonary Bypass: Quo Vadis?
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Anesthesia for Lung Transplantation.
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Anesthetic management of a patient with a brain tumor for cardiac surgery.
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Angiotensin-converting enzyme inhibition alters the inflammatory and fibrinolytic response to cardiopulmonary bypass in children.
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Anomalous Origin of the Left Coronary Artery From the Pulmonary Artery: A Retrospective Multicenter Study.
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Antibodies against heparin-protamine complexes: Effect and clinical relevance.
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Anticoagulant therapy during cardiopulmonary bypass.
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Anticoagulation management associated with extracorporeal circulation.
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Anticoagulation management during cardiopulmonary bypass: a survey of 54 North American institutions.
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Antithrombin deficiency in special clinical syndromes--Part II: cardiovascular surgery.
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Antithrombin deficiency increases thrombin activity after prolonged cardiopulmonary bypass.
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Aortic subannular left ventricular aneurysm: a rare and surgically correctable cause of angina.
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Apolipoprotein E genotype differentially influences the proinflammatory and anti-inflammatory response to cardiopulmonary bypass.
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Aprotinin and the systemic inflammatory response after cardiopulmonary bypass.
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Aprotinin improves functional outcome but not cerebral infarct size in an experimental model of stroke during cardiopulmonary bypass.
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Aprotinin is useful as a hemostatic agent in cardiopulmonary surgery: yes.
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Aprotinin use during cardiac surgery: recent alterations and effects on blood product utilization.
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Aprotinin versus tranexamic acid: the controversy continues.
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Argatroban for anticoagulation during cardiopulmonary bypass in an infant.
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Arterial hyperoxia during cardiopulmonary bypass and postoperative cognitive dysfunction.
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Assessment of left ventricular functional preservation during isolated cardiac valve operations.
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Association of gender and lowest hematocrit on cardiopulmonary bypass with acute kidney injury and operative mortality in patients undergoing cardiac surgery.
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Association of the 98T ELAM-1 polymorphism with increased bleeding after cardiac surgery.
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Atrial arrhythmias after pulmonary thromboendarterectomy.
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Atrial fibrillation after cardiac surgery/cardiopulmonary bypass is associated with monocyte activation.
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BILATERAL PARACENTRAL ACUTE MIDDLE MACULOPATHY AFTER CARDIOPULMONARY BYPASS.
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Bispectral analysis during cardiopulmonary bypass: the effect of hypothermia on the hypnotic state.
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Bivalirudin during cardiopulmonary bypass in patients with previous or acute heparin-induced thrombocytopenia and heparin antibodies: results of the CHOOSE-ON trial.
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Blockade of endothelin-converting enzyme reduces pulmonary hypertension after cardiopulmonary bypass and circulatory arrest.
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Blockade of the extracellular signal-regulated kinase pathway by U0126 attenuates neuronal damage following circulatory arrest.
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CASE 12--2014. Inferior vena cava compression by retroperitoneal hematoma during cardiopulmonary bypass.
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Carboxyhemoglobinemia in a pediatric cardiopulmonary bypass patient derived from a contaminated unit of allogenic blood.
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Cardiac catheterization within 1 to 3 days of proximal aortic surgery is not associated with increased postoperative acute kidney injury.
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Cardiac cryosurgery: effects of myocardial temperature on cryolesion size.
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Cardiac gene delivery with cardiopulmonary bypass.
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Cardiac surgery in infants with low birth weight is associated with increased mortality: analysis of the Society of Thoracic Surgeons Congenital Heart Database.
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Cardioplegia and ventricular late potentials in cardiac surgical patients.
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Cardiopulmonary Bypass Management Complicated by a Stenotic Coronary Sinus and Cold Agglutinins.
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Cardiopulmonary Bypass Strategy for a Cyanotic Child With Hemoglobin SC Disease.
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Cardiopulmonary bypass and the central nervous system: potential for cerebral protection.
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Cardiopulmonary bypass decreases G protein-coupled receptor kinase activity and expression in human peripheral blood mononuclear cells.
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Cardiopulmonary bypass induces leukocyte-platelet adhesion.
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Cardiopulmonary bypass induces neurologic and neurocognitive dysfunction in the rat.
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Cardiopulmonary bypass is associated with hemolysis and acute kidney injury in neonates, infants, and children*.
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Cardiopulmonary bypass reduces the minimum alveolar concentration for isoflurane.
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Cardiopulmonary bypass time does not affect cerebral blood flow.
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Case 1-2011: The challenges posed by a complicated pulmonary thromboendarterectomy.
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Case 4--1998. Cardiopulmonary bypass and hypothermic circulatory arrest for basilar artery aneurysm clipping.
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Case 4-2011: malignant hyperthermia in cardiac surgery.
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Case 6--1998. Perioperative anesthetic management of a patient presenting for resection of a tracheal mass.
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Case 6--1999. Off-pump coronary artery bypass graft surgery.
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Case 6-2011: Aortic valve replacement in a patient with aortic stenosis, dilated cardiomyopathy, and renal dysfunction.
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Cerebral blood flow and metabolism during cardiopulmonary bypass.
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Cerebral blood flow values during cardiopulmonary bypass: relatively absolute or absolutely relative?
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Cerebral emboli and serum S100beta during cardiac operations.
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Cerebral physiologic effects of burst suppression doses of propofol during nonpulsatile cardiopulmonary bypass. CNS Subgroup of McSPI.
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Cerebral physiology of cardiac surgical patients treated with the perfluorocarbon emulsion, AF0144.
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Change in plasma glutamate concentration during cardiac surgery is a poor predictor of cognitive outcome.
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Changes in health-related quality of life in off-pump versus on-pump cardiac surgery: Veterans Affairs Randomized On/Off Bypass trial.
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Changes in regional myocardial function after coronary artery bypass graft surgery are predicted by intraoperative low-dose dobutamine echocardiography.
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Changing systems for measuring activated clotting times: impact on the clinical practice of heparin anticoagulation during cardiac surgery.
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Clinical outcomes of cardiac surgery patients undergoing therapeutic plasma exchange for heparin-induced thrombocytopenia.
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Clopidogrel use After Myocardial Revascularization: Prevalence, Predictors, and One-Year Survival Rate.
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Coagulation and fibrinolytic protein kinetics in cardiopulmonary bypass.
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Coagulation complicating cardiopulmonary bypass in a patient with heparin-induced thrombocytopenia receiving the heparinoid, danaparoid sodium.
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Coagulopathy after cardiopulmonary bypass in Jehovah's Witness patients: management of two cases using fractionated components and factor VIIa.
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Coagulopathy and inflammation in neonatal heart surgery: mechanisms and strategies.
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Combination of aptamer and drug for reversible anticoagulation in cardiopulmonary bypass.
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Combined TMR and mitral valve replacement via left thoracotomy.
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Combining Heparin and a FX/Xa Aptamer to Reduce Thrombin Generation in Cardiopulmonary Bypass and COVID-19.
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Comparing two strategies of cardiopulmonary bypass cooling on jugular venous oxygen saturation in neonates and infants.
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Con: Magnesium should not be administered to all coronary artery bypass graft surgery patients undergoing cardiopulmonary bypass.
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Con: Methylprednisolone is not indicated for patients during cardiopulmonary bypass.
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Concomitant carotid endarterectomy and cardiac surgery does not decrease postoperative stroke rates.
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Conduction block after cardioplegic arrest: prevention by augmented atrial hypothermia.
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Continuous arterial and venous blood gas monitoring during cardiopulmonary bypass.
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Continuous jugular venous versus nasopharyngeal temperature monitoring during hypothermic cardiopulmonary bypass for cardiac surgery.
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Conventional Ultrafiltration During Elective Cardiac Surgery and Postoperative Acute Kidney Injury.
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Conversion From Off-Pump Coronary Artery Bypass Grafting to On-Pump Coronary Artery Bypass Grafting.
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Coronary artery bypass graft failure after on-pump and off-pump coronary artery bypass: findings from PREVENT IV.
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Coronary artery bypass grafting after aprotinin: are we doing better?
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Coronary-Artery Bypass Grafting.
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Corticosteroids and outcome in children undergoing congenital heart surgery: analysis of the Pediatric Health Information Systems database.
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Cost-benefit and efficacy of aprotinin compared with epsilon-aminocaproic acid in patients having repeated cardiac operations: a randomized, blinded clinical trial.
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Deep hypothermia markedly activates the small ubiquitin-like modifier conjugation pathway; implications for the fate of cells exposed to transient deep hypothermic cardiopulmonary bypass.
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Deep hypothermic circulatory arrest and the femoral-to-radial arterial pressure gradient.
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Development of a novel blood-sparing agent in cardiac surgery: do we need another agent?
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Dexmedetomidine Pharmacokinetics and a New Dosing Paradigm in Infants Supported With Cardiopulmonary Bypass.
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Diabetic patients have abnormal cerebral autoregulation during cardiopulmonary bypass.
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Differential age effects of mean arterial pressure and rewarming on cognitive dysfunction after cardiac surgery.
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Differential cardiac gene expression during cardiopulmonary bypass: ischemia-independent upregulation of proinflammatory genes.
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Differential cerebral gene expression during cardiopulmonary bypass in the rat: evidence for apoptosis?
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Discordance in Grading Methods of Aortic Stenosis by Pre-Cardiopulmonary Bypass Transesophageal Echocardiography.
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Donepezil for cognitive decline following coronary artery bypass surgery: a pilot randomized controlled trial.
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Dose dependent effects of cardiac beta2 adrenoceptor gene therapy.
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Early and late forms of cyclosporine nephrotoxicity: studies in cardiac transplant recipients.
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Echo rounds: Intraoperative delineation of mitral annuloplasty dehiscence using three-dimensional transesophageal echocardiography.
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Effect of aging on cerebral autoregulation during cardiopulmonary bypass. Association with postoperative cognitive dysfunction.
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Effect of apolipoprotein E genotype on cerebral autoregulation during cardiopulmonary bypass.
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Effect of combined anticoagulation using heparin and bivalirudin on the hemostatic and inflammatory responses to cardiopulmonary bypass in the rat.
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Effect of intravenous lidocaine on the transcerebral inflammatory response during cardiac surgery: a randomized-controlled trial.
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Effect of levosimendan on survival and adverse events after cardiac surgery: a meta-analysis.
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Effect of mode of intraoperative support on primary graft dysfunction after lung transplant.
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Effect of perfusion pressure on cerebral blood flow during normothermic cardiopulmonary bypass.
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Effect of pregabalin on cerebral outcome after cardiopulmonary bypass with deep hypothermic circulatory arrest in rats.
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Effect of temperature during cardiopulmonary bypass on gastric mucosal perfusion.
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Effect of two doses of tranexamic acid on fibrinolysis evaluated by thromboelastography during cardiac surgery: a randomised, controlled study.
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Effects of C5 complement inhibitor pexelizumab on outcome in high-risk coronary artery bypass grafting: combined results from the PRIMO-CABG I and II trials.
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Effects of aortopulmonary collaterals on cerebral cooling and cerebral metabolic recovery after circulatory arrest.
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Effects of cardiopulmonary bypass and circulatory arrest on endothelium-dependent vasodilation in the lung.
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Effects of deep hypothermic circulatory arrest on the blood brain barrier in a cardiopulmonary bypass model--a pilot study.
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Effects of pyridoxal-5'-phosphate (MC-1) in patients undergoing high-risk coronary artery bypass surgery: results of the MEND-CABG randomized study.
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Efficacy and safety of heparinase I versus protamine in patients undergoing coronary artery bypass grafting with and without cardiopulmonary bypass.
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Efficacy and safety of pyridoxal 5'-phosphate (MC-1) in high-risk patients undergoing coronary artery bypass graft surgery: the MEND-CABG II randomized clinical trial.
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Efficacy and safety of recombinant factor XIII on reducing blood transfusions in cardiac surgery: a randomized, placebo-controlled, multicenter clinical trial.
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Efficacy of Nitric Oxide Administration During Neonatal Cardiopulmonary Bypass.
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Electrophysiologic effects of surgical isolation of the right ventricle.
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Emerging applications of aptamers for anticoagulation and hemostasis.
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Encircling endocardial ventriculotomy for refractory ischemic ventricular tachycardia. II. Effects on regional myocardial blood flow.
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Encircling endocardial ventriculotomy for refractory ischemic ventricular tachycardia. III. Effects on regional left ventricular function.
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Endovascular thoracic aortic aneurysm repair with concomitant myocardial and carotid revascularization.
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Enhancement of cardiac function by cyclocreatine in models of cardiopulmonary bypass.
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Epicardial activation and repolarization patterns in patients with right ventricular hypertrophy.
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Evaluation of dynamic parameters of thrombus formation measured on whole blood using rotational thromboelastometry in children undergoing cardiac surgery: a descriptive study.
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Evaluation of patients at risk for protamine reactions.
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Exacerbation of systemic inflammation and increased cerebral infarct volume with cardiopulmonary bypass after focal cerebral ischemia in the rat.
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Exposure of difficult left hilum in bilateral sequential lung transplantation.
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Factor XII deficiency and cardiopulmonary bypass: use of a novel modification of the activated clotting time to monitor anticoagulation.
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False-positive diagnosis of aortic dissection associated with femoral cardiopulmonary bypass.
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Feeling the heat.
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Genetic factors contribute to bleeding after cardiac surgery.
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Genetic polymorphisms and the risk of stroke after cardiac surgery.
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Grading Aortic Stenosis With Mean Gradient and Aortic Valve Area: A Comparison Between Preoperative Transthoracic and Precardiopulmonary Bypass Transesophageal Echocardiography.
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Grand mal seizure during cardiopulmonary bypass: probable lidocaine toxicity.
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Heated Humidified Breathing Circuit Rewarming in Hypothermic Patients Post-Cardiopulmonary Bypass-Pilot Study.
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Hemodilution during cardiopulmonary bypass increases cerebral infarct volume after middle cerebral artery occlusion in rats.
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Hemostatic agents and their safety.
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Heparin modifies the immunogenicity of positively charged proteins.
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Heparin neutralization by recombinant platelet factor 4 and protamine.
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Heparin neutralization with methylene blue, hexadimethrine, or vancomycin after cardiopulmonary bypass.
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Heparin resistance and antithrombin: should it still be called heparin resistance?
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Heparin therapy during cardiopulmonary bypass in children requires ongoing quality control.
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Heparin-Induced Thrombocytopenia: A Review for Cardiac Anesthesiologists and Intensivists.
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Heparin-induced thrombocytopenia: bovine versus porcine heparin in cardiopulmonary bypass surgery.
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High incidence of antibodies to protamine and protamine/heparin complexes in patients undergoing cardiopulmonary bypass.
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High-Velocity Jet in the Right Atrium: What Is the Diagnosis?
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Home surveillance program prevents interstage mortality after the Norwood procedure.
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How best to monitor for detection of myocardial ischemia?
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Hydroxocobalamin or Methylene Blue for Vasoplegic Syndrome in Adult Cardiothoracic Surgery.
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Immediate versus delayed coronary grafting after streptokinase treatment. Postoperative blood loss and clinical results.
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Impact of Operative and Postoperative Factors on Neurodevelopmental Outcomes After Cardiac Operations.
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Impact of postoperative hyperglycemia following surgical repair of congenital cardiac defects.
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Impact of residency status on perfusion times and outcomes for coronary artery bypass graft surgery.
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Improved clot formation by combined administration of activated factor VII (NovoSeven) and fibrinogen (Haemocomplettan P).
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Inadvertent development of subatmospheric airway pressure during cardiopulmonary bypass.
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Incidence and Impact of On-Cardiopulmonary Bypass Vasoplegia During Heart Transplantation.
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Incidental Cold Agglutinins in Cardiac Surgery: Intraoperative Surprises and Team-Based Problem-Solving Strategies During Cardiopulmonary Bypass.
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Increased anticoagulation during cardiopulmonary bypass by aprotinin.
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Infant cardiopulmonary bypass: CD73 kinetics, association with clinical outcomes, and influence on serum adenosine production capacity.
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Infant cardiopulmonary bypass: a procoagulant state.
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Inflammation and cardiopulmonary bypass.
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Inflammatory gene polymorphisms and risk of postoperative myocardial infarction after cardiac surgery.
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Inflammatory response to cardiopulmonary bypass.
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Influence of hypothermic cardiopulmonary bypass on atrial natriuretic factor levels.
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Influence of the timing of cardiac catheterization and the amount of contrast media on acute renal failure after cardiac surgery.
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Inhibition of complement activation by pexelizumab reduces death in patients undergoing combined aortic valve replacement and coronary artery bypass surgery.
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Inhibition of factor IXa by the pegnivacogin system during cardiopulmonary bypass: a potential substitute for heparin. A study in baboons.
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Intermittent perfusion protects the brain during deep hypothermic circulatory arrest.
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International Society of Cardiovascular Infectious Diseases Guidelines for the Diagnosis, Treatment and Prevention of Disseminated Mycobacterium chimaera Infection Following Cardiac Surgery with Cardiopulmonary Bypass.
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Intestinal mast cells mediate gut injury and systemic inflammation in a rat model of deep hypothermic circulatory arrest.
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Intramyocardial air causes right ventricular dysfunction after repair of a congenital heart defect.
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Intraoperative Methadone for the Prevention of Postoperative Pain: A Randomized, Double-blinded Clinical Trial in Cardiac Surgical Patients.
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Intraoperative echocardiography is indicated in high-risk coronary artery bypass grafting.
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Intraoperative physiologic variables and outcome in cardiac surgery: Part I. In-hospital mortality.
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Intraoperative prebypass and postbypass epicardial color flow imaging in the repair of atrioventricular septal defects.
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Intraoperative pulmonary artery stenting: an alternative technique for the management of pulmonary artery stenosis.
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Intraoperative use of low-dose recombinant activated factor VII during thoracic aortic operations.
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Intraoperative vasoplegia: methylene blue to the rescue!
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Intravenous milrinone in cardiac surgery.
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Invited commentary.
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Invited commentary.
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Is there a long-term predictive value of intraoperative low-dose dobutamine echocardiography in patients who have coronary artery bypass graft surgery with cardiopulmonary bypass?
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Jugular bulb saturation and cognitive dysfunction after cardiopulmonary bypass.
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Levosimendan in patients with left ventricular systolic dysfunction undergoing cardiac surgery on cardiopulmonary bypass: Rationale and study design of the Levosimendan in Patients with Left Ventricular Systolic Dysfunction Undergoing Cardiac Surgery Requiring Cardiopulmonary Bypass (LEVO-CTS) trial.
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Liquid ventilation improves pulmonary function and cardiac output in a neonatal swine model of cardiopulmonary bypass.
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Long-term outcome after biologic versus mechanical aortic valve replacement in 841 patients.
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Longitudinal assessment of neurocognitive function after coronary-artery bypass surgery.
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Longitudinal assessment of neurocognitive function in rats after cardiopulmonary bypass: evidence for long-term deficits.
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Low-flow cardiopulmonary bypass produces greater pulmonary dysfunction than circulatory arrest.
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Lymphocyte and monocyte subset changes during cardiopulmonary bypass: effects of aging and gender.
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Magnesium supplementation during cardiopulmonary bypass to prevent junctional ectopic tachycardia after pediatric cardiac surgery: a randomized controlled study.
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Magnesium therapy for refractory ventricular fibrillation.
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Maintenance of therapeutic plasma aprotinin levels during prolonged cardiopulmonary bypass using a large-dose regimen.
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Management and prevention of cardiovascular hemorrhage associated with mediastinitis.
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Massive pulmonary hemorrhage after pulmonary thromboendarterectomy.
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Measurement of myocardial perfusion by contrast echocardiography: application in the operating room.
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Mediastinitis after coronary artery bypass graft surgery. Risk factors and long-term survival.
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Metabolic deterioration during global ischemia as a function of time in the intact normal dog heart.
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Metabolomic Fingerprinting of Infants Undergoing Cardiopulmonary Bypass: Changes in Metabolic Pathways and Association With Mortality and Cardiac Intensive Care Unit Length of Stay.
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Metabolomic profiling reveals distinct patterns of myocardial substrate use in humans with coronary artery disease or left ventricular dysfunction during surgical ischemia/reperfusion.
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Mini-circuit cardiopulmonary bypass with vacuum assisted venous drainage: feasibility of an asanguineous prime in the neonate.
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Minimally Invasive Pulmonary Fibroelastoma Resection.
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Mitral surgery after prior cardiac operation: port-access versus sternotomy or thoracotomy.
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Modified ultrafiltration improves cerebral metabolic recovery after circulatory arrest.
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Modulation of platelet surface adhesion receptors during cardiopulmonary bypass.
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Monitoring of the electrical status of the ventricle during cardioplegic arrest.
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Monitoring the jugular-venous oxyhemoglobin saturation as a decision aid for normothermic cardiopulmonary bypass.
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Multicenter Evaluation of the Quantra QPlus System in Adult Patients Undergoing Major Surgical Procedures.
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Myocardial blood flow and oxygen consumption in the empty-beating, fibrillating, and potassium-arrested hypertrophied canine heart.
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Myogenic constriction of human coronary arterioles.
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Natural history of nonimmune-mediated thrombocytopenia and acute kidney injury in pediatric open-heart surgery.
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Neurobehavioral evaluation of neonates with congenital heart disease: a cohort study.
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Neurocognitive function after coronary-artery bypass surgery.
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Neurologic outcomes after coronary artery bypass grafting with and without cardiopulmonary bypass.
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Neurological injury during cardiopulmonary bypass in the rat.
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Neuromonitoring Modalities in Pediatric Cardiac Anesthesia: A Review of the Literature.
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Neutrophil CD11b upregulation during cardiopulmonary bypass is associated with postoperative renal injury.
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New paradigms in cardiovascular medicine: emerging technologies and practices: perioperative genomics.
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Noncardiogenic pulmonary edema and rhabdomyolsis after protamine administration in a patient with unrecognized McArdle's disease.
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Novel emboli protection cannula during cardiac surgery: first animal study.
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Off-pump bypass surgery--ready for the big dance?
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Off-pump techniques benefit men and women and narrow the disparity in mortality after coronary bypass grafting.
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Off-pump versus on-pump coronary artery bypass surgery and postoperative renal dysfunction.
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On-pump versus off-pump coronary artery bypass surgery: cost-effectiveness analysis alongside a multisite trial.
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Optimizing liquid ventilation as a lung protection strategy for neonatal cardiopulmonary bypass: full functional residual capacity dosing is more effective than half functional residual capacity dosing.
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Outcomes of off-pump versus on-pump coronary artery bypass grafting: Impact of preoperative risk.
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Overcoming underpowering: Trial simulations and a global rank end point to optimize clinical trials in children with heart disease.
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Overview of clinical efficacy and safety of pharmacologic strategies for blood conservation.
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Oxidative stress and nerve function after cardiopulmonary bypass in patients with diabetes.
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Paroxysmal cold hemoglobinuria and cardiopulmonary bypass.
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Patterns of use of perioperative angiotensin-converting enzyme inhibitors in coronary artery bypass graft surgery with cardiopulmonary bypass: effects on in-hospital morbidity and mortality.
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Perflubron emulsion (AF0144) augments harvesting of autologous blood: a phase II study in cardiac surgery.
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Perfluorocarbon administration during cardiopulmonary bypass in rats: an inflammatory link to adverse outcome?
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Perioperative Corticosteroids in Children Undergoing Congenital Heart Surgery: Five Decades of Clinical Equipoise.
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Perioperative blood transfusion and blood conservation in cardiac surgery: the Society of Thoracic Surgeons and The Society of Cardiovascular Anesthesiologists clinical practice guideline.
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Perioperative nesiritide and possible renal protection in patients with moderate to severe kidney dysfunction.
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Perioperative renal dysfunction and cardiovascular anesthesia: concerns and controversies.
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Periventricular leukomalacia is common after neonatal cardiac surgery.
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Pexelizumab reduces death and myocardial infarction in higher risk cardiac surgical patients.
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Pharmacokinetics and safety of TP10, soluble complement receptor 1, in infants undergoing cardiopulmonary bypass.
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Pharmacokinetics of amrinone during cardiac surgery.
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Pharmacokinetics of intravenous milrinone in patients undergoing cardiac surgery.
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Pharmacokinetics of recombinant transgenic antithrombin in volunteers.
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Pharmacologic electroencephalographic suppression during cardiopulmonary bypass: a comparison of thiopental and isoflurane.
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Pharmacologic preservation of the hemostatic system during cardiac surgery.
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Pharmacologically dosed oral glutamine reduces myocardial injury in patients undergoing cardiac surgery: a randomized pilot feasibility trial.
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Platelet PlA2 polymorphism and platelet activation are associated with increased troponin I release after cardiopulmonary bypass.
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Platelet PlA2 polymorphism enhances risk of neurocognitive decline after cardiopulmonary bypass. Multicenter Study of Perioperative Ischemia (McSPI) Research Group.
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Platelet function analyzer (PFA)-100 closure time in the evaluation of platelet disorders and platelet function.
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Platelet inhibitors and bleeding in cardiac surgical patients.
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Platelet inhibitors and cardiac surgery.
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Population Pharmacokinetic/Pharmacodynamic Modeling of Methylprednisolone in Neonates Undergoing Cardiopulmonary Bypass.
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Population pharmacokinetics of lidocaine administered during and after cardiac surgery.
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Postoperative hyperthermia following off-pump versus on-pump coronary artery bypass surgery.
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Postoperative hyperthermia is associated with cognitive dysfunction after coronary artery bypass graft surgery.
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Pre-operative homocysteine levels and morbidity and mortality following cardiac surgery.
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Predicting and preventing adverse neurologic outcomes with cardiac surgery.
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Predicting and treating coagulopathies after cardiopulmonary bypass in children.
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Predicting mortality in patients with disseminated intravascular coagulation after cardiopulmonary bypass surgery by utilizing two scoring systems.
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Predictors of cognitive decline after cardiac operation.
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Predictors of contemporary coronary artery bypass grafting outcomes.
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Predictors of inotrope use during separation from cardiopulmonary bypass.
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Preliminary report of a genetic basis for cognitive decline after cardiac operations. The Neurologic Outcome Research Group of the Duke Heart Center.
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Preoperative low molecular weight heparin reduces heparin responsiveness during cardiac surgery.
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Preoperative statin therapy does not reduce cognitive dysfunction after cardiopulmonary bypass.
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Prevalence and repair of intraoperatively diagnosed patent foramen ovale and association with perioperative outcomes and long-term survival.
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Prevalence of heparin-associated antibodies without thrombosis in patients undergoing cardiopulmonary bypass surgery.
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Prevention of cerebral hyperthermia during cardiac surgery by limiting on-bypass rewarming in combination with post-bypass body surface warming: a feasibility study.
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Pro: The Value of Modified Ultrafiltration in Children After Cardiopulmonary Bypass.
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Pro: Vasopressin is the vasoconstrictor of choice after cardiopulmonary bypass.
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Prolonged postoperative respiratory support after proximal thoracic aortic surgery: Is deep hypothermic circulatory arrest a risk factor?
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Prolonged pulmonary support after cardiac surgery: incidence, risk factors and outcomes: a retrospective cohort study.
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Prospective evaluation of risk of protamine reactions in patients with NPH insulin-dependent diabetes.
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Protamine reversal of heparin affects platelet aggregation and activated clotting time after cardiopulmonary bypass.
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Protecting the brain in coronary artery bypass graft surgery.
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Proteomic Analysis of Infants Undergoing Cardiopulmonary Bypass Using Contemporary Ontological Tools.
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Proteomics of cerebral injury in a neonatal model of cardiopulmonary bypass with deep hypothermic circulatory arrest.
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Prothrombin Complex Concentrate vs Plasma for Post-Cardiopulmonary Bypass Coagulopathy and Bleeding: A Randomized Clinical Trial.
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Quantification of the contractile response to injury: assessment of the work-length relationship in the intact heart.
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Randomized evaluation of fibrinogen vs placebo in complex cardiovascular surgery (REPLACE): a double-blind phase III study of haemostatic therapy.
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Rapid evaluation of coagulopathies after cardiopulmonary bypass in children using modified thromboelastography.
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Rationale and design of the STeroids to REduce Systemic inflammation after infant heart Surgery (STRESS) trial.
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Recent Advances in Congenital Heart Surgery: Alternative Perfusion Strategies for Infant Aortic Arch Repair.
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Recombinant human antithrombin III restores heparin responsiveness and decreases activation of coagulation in heparin-resistant patients during cardiopulmonary bypass.
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Recovery of cerebral metabolism and mitochondrial oxidation state is delayed after hypothermic circulatory arrest.
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Reduction in blood transfusion in a cohort of infants having cardiac surgery with cardiopulmonary bypass after instituting a goal-directed transfusion policy.
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Relationship between serum lactate and ionized calcium in open-heart surgery.
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Relationship of LV compliance to coronary artery perfusion pressure in potassium-arrested canine heart during cardiopulmonary bypass.
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Relationship of genetic variability and depressive symptoms to adverse events after coronary artery bypass graft surgery.
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Renal artery stenosis is not associated with the development of acute renal failure following coronary artery bypass grafting.
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Renal medullary hypoxia during experimental cardiopulmonary bypass: a pilot study.
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Replacement of continuous-flow left ventricular assist device via left subcostal incision.
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Repletion of factor XIII following cardiopulmonary bypass using a recombinant A-subunit homodimer. A preliminary report.
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Reply: Alternative arterial cannulation in aortic arch surgery.
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Reply: To PMID 23673070.
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Reply: To PMID 24266946.
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Report of a substudy on warm versus cold cardiopulmonary bypass: changes in creatinine clearance.
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Results with an algorithmic approach to hybrid repair of the aortic arch.
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Right ventricular rupture during off-pump coronary bypass surgery.
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Right ventricular sensitivity to metabolic injury during cardiopulmonary bypass.
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Risk factors for mortality and morbidity after the neonatal Blalock-Taussig shunt procedure.
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Risk index for perioperative renal dysfunction/failure: critical dependence on pulse pressure hypertension.
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Robotic Mitral Valve Repair in Older Individuals: An Analysis of The Society of Thoracic Surgeons Database.
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Routine use of intraoperative epicardial echocardiography and Doppler color flow imaging to guide and evaluate repair of congenital heart lesions. A prospective study.
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S100beta and postcardiac surgery neurological dysfunction: reasons to disregard any link.
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Skeletal muscle grafts applied to the heart. A word of caution.
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Soluble alpha2-macroglobulin receptor is increased in endotracheal aspirates from infants and children after cardiopulmonary bypass.
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Sonorheometry assessment of platelet function in cardiopulmonary bypass patients: Correlation of blood clot stiffness with platelet integrin αIIbβ3 activity, aspirin usage, and transfusion risk.
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Surgery. Translating trials to clinical practice in cardiac surgery.
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Surgical Treatment of Acute Massive Pulmonary Embolism.
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Surgical ablation of atrial fibrillation trends and outcomes in North America.
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Synchronous rhythmical vasomotion in the human cutaneous microvasculature during nonpulsatile cardiopulmonary bypass.
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Terminal complement blockade with pexelizumab during coronary artery bypass graft surgery requiring cardiopulmonary bypass: a randomized trial.
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The "sandblasting" effect of aortic cannula on arch atheroma during cardiopulmonary bypass.
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The Association of Aortic Valve Pathology With Renal Resistive Index as a Kidney Injury Biomarker.
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The Bayley-III scale may underestimate neurodevelopmental disability after cardiac surgery in infants.
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The Contact Activation System: Problems and Paradoxes for Cardiac Anesthesiologists.
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The association of complication type with mortality and prolonged stay after cardiac surgery with cardiopulmonary bypass.
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The association of epsilon-aminocaproic acid with postoperative decrease in creatinine clearance in 1502 coronary bypass patients.
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The association of lowest hematocrit during cardiopulmonary bypass with acute renal injury after coronary artery bypass surgery.
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The association of renal dysfunction and the use of aprotinin in patients undergoing congenital cardiac surgery requiring cardiopulmonary bypass.
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The current practice of intra-aortic balloon counterpulsation: results from the Benchmark Registry.
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The effect of aprotinin on activated protein C-mediated downregulation of endogenous thrombin generation.
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The effect of blood pressure on cerebral outcome in a rat model of cerebral air embolism during cardiopulmonary bypass.
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The effect of cardiopulmonary bypass and inspired oxygen concentration on left ventricular contrast opacification with optison, a second-generation ultrasound contrast agent.
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The effect of milrinone on hemodynamics and left ventricular function after emergence from cardiopulmonary bypass.
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The effect of temperature on cerebral metabolism and blood flow in adults during cardiopulmonary bypass.
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The effects of MDCO-2010, a serine protease inhibitor, on activated clotting time in blood obtained from volunteers and cardiac surgical patients.
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The effects of cardiopulmonary bypass on coagulation.
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The effects of milrinone on platelets in patients undergoing cardiac surgery.
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The in vitro effects of antithrombin III on the activated coagulation time in patients on heparin therapy.
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The inflammatory response to cardiopulmonary bypass.
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The influence of xenon, nitrous oxide and nitrogen on gas bubble expansion during cardiopulmonary bypass.
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The kaolin-activated Thrombelastograph predicts bleeding after cardiac surgery.
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The plasma supplemented modified activated clotting time for monitoring of heparinization during cardiopulmonary bypass: a pilot investigation.
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The relationship between immediate outcome after cardiac surgery, homogeneous cardioplegia delivery, and ejection fraction.
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The rewarming rate and increased peak temperature alter neurocognitive outcome after cardiac surgery.
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The risk of acute kidney injury with co-occurrence of anemia and hypotension during cardiopulmonary bypass relative to anemia alone.
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The systemic inflammatory response to cardiopulmonary bypass: pathophysiological, therapeutic, and pharmacological considerations.
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The use of TP10, soluble complement receptor 1, in cardiopulmonary bypass.
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The use of acute normovolemic hemodilution in paediatric cardiac surgery.
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The utility of transesophageal echocardiography and Doppler color flow imaging in patients undergoing cardiac valve surgery.
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The year in cardiothoracic and vascular anesthesia: selected highlights from 2013.
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Three-factor prothrombin complex concentrates for refractory bleeding after cardiovascular surgery within an algorithmic approach to haemostasis.
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Time limits for submersion of canine left ventricular biopsies in cold isopentane.
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Transcerebral platelet activation after aortic cross-clamp release is linked to neurocognitive decline.
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Transcranial Doppler blood flow velocity versus 133Xe clearance cerebral blood flow during mild hypothermic cardiopulmonary bypass.
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Transcranial Doppler emboli count predicts rise in creatinine after coronary artery bypass graft surgery.
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Transplantation of high panel-reactive antibody left ventricular assist device patients without crossmatch using on-bypass pheresis and alemtuzumab.
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Treatment of non-cardiogenic pulmonary edema following cardiopulmonary bypass with veno-venous extracorporeal membrane oxygenation.
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Two-stage total cardioaortic replacement for end-stage heart and aortic disease in Marfan syndrome: case report and review of the literature.
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Unreliability of hemodynamic indexes of left ventricular size during cardiac surgery.
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Unusual cause of superior vena cava syndrome diagnosed with transesophageal echocardiography.
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Urine NGAL as a biomarker of kidney damage after on- and off-pump coronary artery bypass graft surgery: a prospective pilot study.
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Use of Adjuncts Reduces Cardiopulmonary Bypass Time During Minimally Invasive Aortic Valve Replacement.
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Use of cardiopulmonary bypass in studies of the circulation.
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Using Zero Balance Ultrafiltration with Dialysate as a Replacement Fluid for Hyperkalemia during Cardiopulmonary Bypass.
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Using Zero-Balance Ultrafiltration With Dialysate as a Replacement Solution for Toxin and Eptifibatide Removal on a Dialysis-Dependent Patient During Cardiopulmonary Bypass.
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Utility of concomitant tricuspid valve procedures for patients undergoing implantation of a continuous-flow left ventricular device.
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Venous admixture to radial artery blood samples during cardiopulmonary bypass.
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Viscoelastic testing to assess the effects of rapid fibrinogen concentrate administration after cardiopulmonary bypass: insights from the REPLACE study.
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Warming during cardiopulmonary bypass is associated with jugular bulb desaturation.
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Xenon and the inflammatory response to cardiopulmonary bypass in the rat.
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Xenon attenuates cardiopulmonary bypass-induced neurologic and neurocognitive dysfunction in the rat.
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beta2 adrenoceptor gene therapy ameliorates left ventricular dysfunction following cardiac surgery.
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epsilon-Aminocaproic acid plasma levels during cardiopulmonary bypass.
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pH-stat cooling improves cerebral metabolic recovery after circulatory arrest in a piglet model of aortopulmonary collaterals.
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Keywords of People
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Alexander, John Hunter Peel,
Professor of Medicine,
Medicine, Cardiology
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Barbeito, Atilio,
Associate Professor of Anesthesiology,
Anesthesiology
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Levy, Jerrold Henry,
Professor of Anesthesiology,
Anesthesiology, Cardiothoracic
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Milano, Carmelo Alessio,
Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery,
Surgery, Cardiovascular and Thoracic Surgery
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Stinnett, Sandra Sue,
Associate Professor of Biostatistics & Bioinformatics,
Biostatistics & Bioinformatics
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Swaminathan, Madhav,
Professor of Anesthesiology,
Anesthesiology, Cardiothoracic
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Turi, Jennifer Lilly,
Associate Professor of Pediatrics,
Pediatrics, Critical Care Medicine