Carrier Proteins

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  Subject Areas on Research

  • "Model" behavior. 
  • 4-oxatetradecanoic acid is fungicidal for Cryptococcus neoformans and inhibits replication of human immunodeficiency virus I. 
  • 5-Lipoxygenase-activating protein is the target of a quinoline class of leukotriene synthesis inhibitors. 
  • 5alpha-Dihydrotestosterone binding to androgen binding protein. Effects of testosterone and other compounds in vivo and in vitro on the number of binding sites measured. 
  • A Mets motif peptide found in copper transport proteins selectively binds Cu(I) with methionine-only coordination. 
  • A PGC1β genetic variant associated with nevus count and melanoma mortality. 
  • A PK2/Bv8/PROK2 antagonist suppresses tumorigenic processes by inhibiting angiogenesis in glioma and blocking myeloid cell infiltration in pancreatic cancer. 
  • A carcinoembryonic antigen (CEA) binding protein from ascites influences CEA uptake by macrophages. 
  • A common RNA recognition motif identified within a defined U1 RNA binding domain of the 70K U1 snRNP protein. 
  • A crucial role of L-selectin in C protein-induced experimental polymyositis in mice. 
  • A defined human system that supports bidirectional mismatch-provoked excision. 
  • A founder mutation in the Ashkenazi Jewish population affecting messenger RNA splicing of the CCM2 gene causes cerebral cavernous malformations. 
  • A gene on chromosome 11q23 coding for a putative glucose- 6-phosphate translocase is mutated in glycogen-storage disease types Ib and Ic. 
  • A gene therapy strategy using a transcription factor decoy of the E2F binding site inhibits smooth muscle proliferation in vivo. 
  • A high-throughput CRISPR interference screen for dissecting functional regulators of GPCR/cAMP signaling. 
  • A human novel gene DERPC on 16q22.1 inhibits prostate tumor cell growth and its expression is decreased in prostate and renal tumors. 
  • A methylthioadenosine phosphorylase (MTAP) fusion transcript identifies a new gene on chromosome 9p21 that is frequently deleted in cancer. 
  • A multi-center, dose-escalation study of human type I pancreatic elastase (PRT-201) administered after arteriovenous fistula creation. 
  • A new face of the Rhesus antigen. 
  • A novel leptin receptor isoform in rat. 
  • A novel mechanism for Bcr-Abl action: Bcr-Abl-mediated induction of the eIF4F translation initiation complex and mRNA translation. 
  • A novel mechanism for regulating transforming growth factor beta (TGF-beta) signaling. Functional modulation of type III TGF-beta receptor expression through interaction with the PDZ domain protein, GIPC. 
  • A novel mutation in the gene encoding noggin is not causative in human neural tube defects. 
  • A novel role for XIAP in copper homeostasis through regulation of MURR1. 
  • A novel ubiquitin fusion system bypasses the mitochondria and generates biologically active Smac/DIABLO. 
  • A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex. 
  • A pathogenic variant in the SETBP1 hotspot results in a forme-fruste Schinzel-Giedion syndrome. 
  • A perspective for understanding the modes of juvenile hormone action as a lipid signaling system. 
  • A phase 1 dose-escalation study of NEO-102 in patients with refractory colon and pancreatic cancer. 
  • A phase II window trial of procarbazine and topotecan in children with high-grade glioma: a report from the children's oncology group. 
  • A phospholipase C-dependent inositol polyphosphate kinase pathway required for efficient messenger RNA export. 
  • A quantitative, high-throughput screen for protein stability. 
  • A structure-based mechanism for drug binding by multidrug transporters. 
  • A suppressor/enhancer screen in Drosophila reveals a role for wnt-mediated lipid metabolism in primordial germ cell migration. 
  • A yeast cyclophilin gene essential for lactate metabolism at high temperature. 
  • ACVR1 R206H cooperates with H3.1K27M in promoting diffuse intrinsic pontine glioma pathogenesis. 
  • ALOX5AP variants are associated with in-stent restenosis after percutaneous coronary intervention. 
  • AQP2 is a substrate for endogenous PP2B activity within an inner medullary AKAP-signaling complex. 
  • ATR functions as a gene dosage-dependent tumor suppressor on a mismatch repair-deficient background. 
  • Abi3bp is a multifunctional autocrine/paracrine factor that regulates mesenchymal stem cell biology. 
  • Abi3bp regulates cardiac progenitor cell proliferation and differentiation. 
  • Abrogation of the Rb/p16 tumor-suppressive pathway in virtually all pancreatic carcinomas. 
  • Activated alpha 2-macroglobulin promotes mitogenesis in rat vascular smooth muscle cells by a mechanism that is independent of growth-factor-carrier activity. 
  • Activation of RalA is critical for Ras-induced tumorigenesis of human cells. 
  • Activation of direct and indirect pathways of glycogen synthesis by hepatic overexpression of protein targeting to glycogen. 
  • Activation of the NLRP3 inflammasome by intracellular poly I:C. 
  • Activation of the Nlrp3 inflammasome by mitochondrial reactive oxygen species: a novel mechanism of albumin-induced tubulointerstitial inflammation. 
  • Adaptor proteins in lymphocyte activation. 
  • Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product. 
  • Adenovirus inhibition of cellular protein synthesis involves inactivation of cap-binding protein. 
  • Administration of atrial natriuretic factor inhibits sodium-coupled transport in proximal tubules. 
  • Adrenoceptors, uncoupling proteins, and energy expenditure. 
  • Affinity chromatography of adrenergic receptors and binding proteins. 
  • AglJ adds the first sugar of the N-linked pentasaccharide decorating the Haloferax volcanii S-layer glycoprotein. 
  • Alleles of the yeast Pms1 mismatch-repair gene that differentially affect recombination- and replication-related processes. 
  • Allelic differences in the serotonin transporter-linked polymorphic region in geriatric depression. 
  • Alpha 2-adrenergic agonists stimulate DNA synthesis in Chinese hamster lung fibroblasts transfected with a human alpha 2-adrenergic receptor gene. 
  • Alpha-fodrin is cleaved by caspase-3 in a chronic ocular hypertensive (COH) rat model of glaucoma. 
  • Alterations in serotonin transporter expression in brain regions of rats exposed neonatally to chlorpyrifos. 
  • Alterations of the X-linked lymphoproliferative disease gene SH2D1A in common variable immunodeficiency syndrome. 
  • Altered lymphocyte responses and cytokine production in mice deficient in the X-linked lymphoproliferative disease gene SH2D1A/DSHP/SAP. 
  • Altered stored calcium release in skeletal myotubes deficient of triadin and junctin. 
  • Alternative splicing of the BSC1 gene generates tissue-specific isoforms in the German cockroach. 
  • Amino acid residues in thrombin-sensitive region and first epidermal growth factor domain of vitamin K-dependent protein S determining specificity of the activated protein C cofactor function. 
  • An auxin-dependent distal organizer of pattern and polarity in the Arabidopsis root. 
  • An intergenic risk locus containing an enhancer deletion in 2q35 modulates breast cancer risk by deregulating IGFBP5 expression. 
  • An oligonucleotide decoy for transcription factor E2F inhibits mesangial cell proliferation in vitro. 
  • An siRNA Screen Identifies the U2 snRNP Spliceosome as a Host Restriction Factor for Recombinant Adeno-associated Viruses. 
  • An undecaprenyl phosphate-aminoarabinose flippase required for polymyxin resistance in Escherichia coli. 
  • Analysis of DNA mismatch repair proteins in human medulloblastoma. 
  • Analysis of FasL and TRAIL induced apoptosis pathways in glioma cells. 
  • Analysis of allosteric signal transduction mechanisms in an engineered fluorescent maltose biosensor. 
  • Analysis of candidate antagonists of IAP-mediated caspase inhibition using yeast reconstituted with the mammalian Apaf-1-activated apoptosis mechanism. 
  • Analysis of phenylthiohydantoin amino acid mixtures for sequencing by thermospray liquid chromatography/mass spectrometry. 
  • Analysis of the role of membrane polarity in polycystic kidney disease of transgenic SBM mice. 
  • Androgen binding protein as a biochemical marker of formation of the blood-testis barrier. 
  • Androgen stimulation of gross cystic disease fluid protein and carcinoembryonic antigen in patients with metastatic breast carcinoma. 
  • Aneuploidy of chromosome 9 and the tumor suppressor genes p16(INK4) and p15(INK4B) detected by in situ hybridization in locally advanced prostate cancer. 
  • Ankyrin-B interactions with spectrin and dynactin-4 are required for dystrophin-based protection of skeletal muscle from exercise injury. 
  • Ankyrin-B is required for coordinated expression of beta-2-spectrin, the Na/K-ATPase and the Na/Ca exchanger in the inner segment of rod photoreceptors. 
  • Ankyrin-G is a molecular partner of E-cadherin in epithelial cells and early embryos. 
  • Ankyrin-binding proteins related to nervous system cell adhesion molecules: candidates to provide transmembrane and intercellular connections in adult brain. 
  • Anterior pituitary hypoplasia and dwarfism in mice lacking the dopamine transporter. 
  • Antifungal effects of cyclosporine and FK 506 are mediated via immunophilin-dependent calcineurin inhibition. 
  • Antisense oligodeoxynucleotide inhibition of vascular angiotensin-converting enzyme expression attenuates neointimal formation: evidence for tissue angiotensin-converting enzyme function. 
  • Antithrombin III, a serpin family protease inhibitor, is a major heparin binding protein in porcine aqueous humor. 
  • Apoptosis and B cell tolerance. 
  • Apoptosis and NF-kappa B: the FADD connection. 
  • Aromatic hydrocarbon receptor interaction with the retinoblastoma protein potentiates repression of E2F-dependent transcription and cell cycle arrest. 
  • Aryl hydrocarbon receptor-mediated up-regulation of ATP-driven xenobiotic efflux transporters at the blood-brain barrier. 
  • Assembly of an A kinase-anchoring protein-beta(2)-adrenergic receptor complex facilitates receptor phosphorylation and signaling. 
  • Association between a functional polymorphism (-1195T>C) in the IGFBP5 promoter and head and neck cancer risk. 
  • Association between human erythrocyte calmodulin and the cytoplasmic surface of human erythrocyte membranes. 
  • Association mapping of the high-grade myopia MYP3 locus reveals novel candidates UHRF1BP1L, PTPRR, and PPFIA2. 
  • Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling. 
  • Association of brain ankyrin with brain membranes and isolation of active proteolytic fragments of membrane-associated ankyrin-binding protein(s). 
  • Association of genetic variants in the HDL receptor, SR-B1, with abnormal lipids in women with coronary artery disease. 
  • Association of polymorphisms in genes regulating the corticotropin-releasing factor system with antidepressant treatment response. 
  • Association of the adaptor molecule LAT with CD4 and CD8 coreceptors identifies a new coreceptor function in T cell receptor signal transduction. 
  • Associations among the NEO Personality Inventory, Revised and the serotonin transporter gene-linked polymorphic region in elders: effects of depression and gender. 
  • Autoradiographic quantification of neurochemical markers of serotonin, dopamine and opioid systems in rat brain mesolimbic regions following chronic St John's wort treatment. 
  • Autosomal-dominant hemochromatosis is associated with a mutation in the ferroportin (SLC11A3) gene. 
  • BCL2 translocation defines a unique tumor subset within the germinal center B-cell-like diffuse large B-cell lymphoma. 
  • BMP antagonism by Noggin is required in presumptive notochord cells for mammalian foregut morphogenesis. 
  • BMP antagonism is required in both the node and lateral plate mesoderm for mammalian left-right axis establishment. 
  • BMP signaling in the development of the mouse esophagus and forestomach. 
  • BMPs induce dermal markers and ectopic feather tracts. 
  • BPIFB3 Regulates Endoplasmic Reticulum Morphology To Facilitate Flavivirus Replication. 
  • BPIFB3 regulates autophagy and coxsackievirus B replication through a noncanonical pathway independent of the core initiation machinery. 
  • BPIFB6 Regulates Secretory Pathway Trafficking and Enterovirus Replication. 
  • BSTA promotes mTORC2-mediated phosphorylation of Akt1 to suppress expression of FoxC2 and stimulate adipocyte differentiation. 
  • Bacterial Nucleoid Occlusion: Multiple Mechanisms for Preventing Chromosome Bisection During Cell Division. 
  • Balancing different types of actin polymerization at distinct sites: roles for Abelson kinase and Enabled. 
  • Bcr-Abl kinase modulates the translation regulators ribosomal protein S6 and 4E-BP1 in chronic myelogenous leukemia cells via the mammalian target of rapamycin. 
  • Benzoate treatment and the glycine index in nonketotic hyperglycinaemia. 
  • Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers. 
  • Biallelic somatic and germline mutations in cerebral cavernous malformations (CCMs): evidence for a two-hit mechanism of CCM pathogenesis. 
  • Binding of activated alpha2-macroglobulin to its cell surface receptor GRP78 in 1-LN prostate cancer cells regulates PAK-2-dependent activation of LIMK. 
  • Binding of the beta2 adrenergic receptor to N-ethylmaleimide-sensitive factor regulates receptor recycling. 
  • Biochemical correlates of temozolomide sensitivity in pediatric solid tumor xenograft models. 
  • Biochemistry. Exciting structures. 
  • Biology of small cell lung cancer. 
  • Biomarkers of inflammation - LBP and TLR- predict progression of knee osteoarthritis in the DOXY clinical trial. 
  • Biosynthesis of EGF receptor, transferrin receptor and colligin by cultured human keratinocytes and the effect of retinoic acid. 
  • Blood group antigens on complement receptor/regulatory proteins. 
  • Bmp signaling is required for intestinal growth and morphogenesis. 
  • Bmp signaling regulates proximal-distal differentiation of endoderm in mouse lung development. 
  • Bmp4 is essential for the formation of the vestibular apparatus that detects angular head movements. 
  • Bonds between fibronectin and fibronectin-binding proteins on Staphylococcus aureus and Lactococcus lactis. 
  • Bone morphogenetic protein 4 mediates myocardial ischemic injury through JNK-dependent signaling pathway. 
  • Bone morphogenetic protein-4 (BMP-4) acts during gastrula stages to cause ventralization of Xenopus embryos. 
  • Brain-derived neurotrophic factor but not vesicular zinc promotes TrkB activation within mossy fibers of mouse hippocampus in vivo. 
  • CCM1 and CCM2 protein interactions in cell signaling: implications for cerebral cavernous malformations pathogenesis. 
  • CD19 regulates innate immunity by the toll-like receptor RP105 signaling in B lymphocytes. 
  • CD28 ligation induces rapid tyrosine phosphorylation of the linker molecule LAT in the absence of Syk and ZAP-70 tyrosine phosphorylation. 
  • CDKN2 in HPV-positive and HPV-negative cervical-carcinoma cell lines. 
  • CHMP5 is essential for late endosome function and down-regulation of receptor signaling during mouse embryogenesis. 
  • CNS1 encodes an essential p60/Sti1 homolog in Saccharomyces cerevisiae that suppresses cyclophilin 40 mutations and interacts with Hsp90. 
  • COMMD proteins, a novel family of structural and functional homologs of MURR1. 
  • COPII-cargo interactions direct protein sorting into ER-derived transport vesicles. 
  • CRHBP polymorphisms predict chronic pain development following motor vehicle collision. 
  • CRL4Mahj E3 ubiquitin ligase promotes neural stem cell reactivation. 
  • Ca++-switch induction of RPE differentiation. 
  • Ca2+-dependent regulator. Production and characterization of a monospecific antibody. 
  • Cadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell death. 
  • Calcineurin is essential in cyclosporin A- and FK506-sensitive yeast strains. 
  • Calcium binding domains and calcium-induced conformational transition of SPARC/BM-40/osteonectin, an extracellular glycoprotein expressed in mineralized and nonmineralized tissues. 
  • Calcium-dependent regulator protein: localization in mitotic apparatus of eukaryotic cells. 
  • Calcium/calmodulin inhibits direct binding of spectrin to synaptosomal membranes. 
  • Calmodulin in bovine rod outer segments. 
  • Cardiac glutaminolysis: a maladaptive cancer metabolism pathway in the right ventricle in pulmonary hypertension. 
  • Cardioprotective proteins upregulated in the liver in response to experimental myocardial ischemia. 
  • Caspase-1-induced pyroptotic cell death. 
  • Caspase-2-mediated cleavage of Mdm2 creates a p53-induced positive feedback loop. 
  • Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells. 
  • Cell biology: A BID for the pathway. 
  • Cell cycle protein expression in vascular smooth muscle cells in vitro and in vivo is regulated through phosphatidylinositol 3-kinase and mammalian target of rapamycin. 
  • Cell cycle: Flies teach an old dogma new tricks. 
  • Cell proliferation is necessary for the determination of male fate in the gonad. 
  • Cell surface polarization during yeast mating. 
  • Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms. 
  • Cellular CD44S as a determinant of human immunodeficiency virus type 1 infection and cellular tropism. 
  • Cellular and molecular responses of the uterus to embryo implantation can be elicited by locally applied growth factors. 
  • Cellular patterns of insulin-like growth factor system gene expression in murine chondrogenesis and osteogenesis. 
  • Central nervous system serotonin function and cardiovascular responses to stress. 
  • Characterization of COMMD protein-protein interactions in NF-kappaB signalling. 
  • Characterization of a cholesterol response element (CRE) in the promoter of the cholesteryl ester transfer protein gene: functional role of the transcription factors SREBP-1a, -2, and YY1. 
  • Characterization of a human plasma membrane heme transporter in intestinal and hepatocyte cell lines. 
  • Characterization of androgen receptor in Sertoli cell-enriched testis. 
  • Characterization of the cell death promoter, Bad, in the developing rat retina and forebrain. 
  • Characterization of the mouse FTZ-F1 gene, which encodes a key regulator of steroid hydroxylase gene expression. 
  • Characterization of the mouse SPARC/osteonectin gene. Intron/exon organization and an unusual promoter region. 
  • Chloride transport inhibitors influence recovery from oxygen-glucose deprivation-induced cellular injury in adult hippocampus. 
  • Chordin and noggin promote organizing centers of forebrain development in the mouse. 
  • Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer. 
  • Cisplatin and adriamycin resistance are associated with MutLalpha and mismatch repair deficiency in an ovarian tumor cell line. 
  • Clathrin is important for normal actin dynamics and progression of Sla2p-containing patches during endocytosis in yeast. 
  • Cloning and characterization of ATRAP, a novel protein that interacts with the angiotensin II type 1 receptor. 
  • Cloning and characterization of developmental endothelial locus-1: an embryonic endothelial cell protein that binds the alphavbeta3 integrin receptor. 
  • Cloning and expression of a novel Na(+)-dependent neutral amino acid transporter structurally related to mammalian Na+/glutamate cotransporters. 
  • Cloning, sequencing, and recombinant expression of the porcine inhibitor of carbonic anhydrase: a novel member of the transferrin family. 
  • Coactivator PRIP, the peroxisome proliferator-activated receptor-interacting protein, is a modulator of placental, cardiac, hepatic, and embryonic development. 
  • Common Genetic Variation In Cellular Transport Genes and Epithelial Ovarian Cancer (EOC) Risk. 
  • Comparative analysis reveals distinctive epigenetic features of the human cerebellum. 
  • Comparative epitope mapping of sera from United States (US) and Japanese patients with bullous pemphigoid (BP) to fusion proteins encoded by BPAG1. 
  • Comparison of in vitro and in vivo differentiation of myeloblastic leukemia of the RFM/Un mouse. 
  • Comprehensive profiling of amino acid response uncovers unique methionine-deprived response dependent on intact creatine biosynthesis. 
  • Compromised CDK1 activity sensitizes BRCA-proficient cancers to PARP inhibition. 
  • Control of cyclin B1 localization through regulated binding of the nuclear export factor CRM1. 
  • Control of electrolyte balance through ubiquitination. 
  • Control of innate immune signaling and membrane targeting by the Hepatitis C virus NS3/4A protease are governed by the NS3 helix α0. 
  • Control of microtubule assembly-disassembly by calcium-dependent regulator protein. 
  • Controlled targeting of liposomal doxorubicin via the folate receptor in vitro. 
  • Convergent control of serotonin transporter expression by glucocorticoids and cocaine in fetal and neonatal rat brain. 
  • Conversion of a maltose receptor into a zinc biosensor by computational design. 
  • Conversion of protein phosphatase 1 catalytic subunit to a Mn(2+)-dependent enzyme impairs its regulation by inhibitor 1. 
  • Converting a maltose receptor into a nascent binuclear copper oxygenase by computational design. 
  • Coordinate changes in C protein and myosin expression during skeletal muscle hypertrophy. 
  • Coordinator's report--section 2D3. 
  • Copine A Interacts with Actin Filaments and Plays a Role in Chemotaxis and Adhesion. 
  • Cross-disorder genomewide analysis of schizophrenia, bipolar disorder, and depression. 
  • Crystal structure of the human LRH-1 DBD-DNA complex reveals Ftz-F1 domain positioning is required for receptor activity. 
  • Cutting edge: Cytosolic bacterial DNA activates the inflammasome via Aim2. 
  • Cutting edge: a role for the adaptor protein LAT in human NK cell-mediated cytotoxicity. 
  • Cyclic adenosine 3',5' monophosphate, calcium and protein phosphorylation in flagellar motility. 
  • Cyclophilin active site mutants have native prolyl isomerase activity with a protein substrate. 
  • Cyclophilin-related protein RanBP2 acts as chaperone for red/green opsin. 
  • Cyclosporine A inhibits Ca2+-dependent stimulation of the Na+/H+ antiport in human T cells. 
  • DDB1 functions as a linker to recruit receptor WD40 proteins to CUL4-ROC1 ubiquitin ligases. 
  • DNA chain length dependence of formation and dynamics of hMutSalpha.hMutLalpha.heteroduplex complexes. 
  • De novo TRIM8 variants impair its protein localization to nuclear bodies and cause developmental delay, epilepsy, and focal segmental glomerulosclerosis. 
  • Defects of the heart, eye, and megakaryocytes in peroxisome proliferator activator receptor-binding protein (PBP) null embryos implicate GATA family of transcription factors. 
  • Definition of a functional single nucleotide polymorphism in the cell migration inhibitory gene MIIP that affects the risk of breast cancer. 
  • Deletion of MLIP (muscle-enriched A-type lamin-interacting protein) leads to cardiac hyperactivation of Akt/mammalian target of rapamycin (mTOR) and impaired cardiac adaptation. 
  • Deletions and rearrangements inactivate the p16INK4 gene in human glioma cells. 
  • Deletions in CCM2 are a common cause of cerebral cavernous malformations. 
  • Deltex1 redirects lymphoid progenitors to the B cell lineage by antagonizing Notch1. 
  • Dependence of the regulation of telomere length on the type of subtelomeric repeat in the yeast Saccharomyces cerevisiae. 
  • Design of bioelectronic interfaces by exploiting hinge-bending motions in proteins. 
  • Design, synthesis, and evaluation of linear and cyclic peptide ligands for PDZ10 of the multi-PDZ domain protein MUPP1. 
  • Detection and characterization of xenon-binding sites in proteins by 129Xe NMR spectroscopy. 
  • Developmental exposure to chlorpyrifos elicits sex-selective alterations of serotonergic synaptic function in adulthood: critical periods and regional selectivity for effects on the serotonin transporter, receptor subtypes, and cell signaling. 
  • Developmental expression of 2ar (osteopontin) and SPARC (osteonectin) RNA as revealed by in situ hybridization. 
  • Developmental pharmacogenomics. 
  • Developmental regulation of insulin-like growth factor binding protein production: studies in fetal, postnatal, and pregnant sheep. 
  • Diet-induced changes in uncoupling proteins in obesity-prone and obesity-resistant strains of mice. 
  • Differences in steroid specificity for rat androgen binding protein and the cytoplasmic receptor. 
  • Different spectra of genomic deletions within the CCM genes between Italian and American CCM patient cohorts. 
  • Differential expression of GABA and glutamate-receptor subunits and enzymes involved in GABA metabolism between electrophysiologically identified hippocampal CA1 pyramidal cells and interneurons. 
  • Differential expression of the 67-kD laminin receptor and 31-kD human laminin-binding protein in human ovarian carcinomas. 
  • Differential inactivation of CDKN2 and Rb protein in non-small-cell and small-cell lung cancer cell lines. 
  • Differential reversal of lipophilic antifolate resistance in mammalian cells with modulators of the multidrug resistance phenotype. 
  • Direct antidiabetic effect of leptin through triglyceride depletion of tissues. 
  • Direct involvement of yeast type I myosins in Cdc42-dependent actin polymerization. 
  • Direct tandem mass spectrometry reveals limitations in protein profiling experiments for plasma biomarker discovery. 
  • Direct visualization of asymmetric adenine-nucleotide-induced conformational changes in MutL alpha. 
  • Disruption of ErbB receptor signaling in adult non-myelinating Schwann cells causes progressive sensory loss. 
  • Disruption of the gene encoding the mitogen-regulated translational modulator PHAS-I in mice. 
  • Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation. 
  • Distinct glycan-charged phosphodolichol carriers are required for the assembly of the pentasaccharide N-linked to the Haloferax volcanii S-layer glycoprotein. 
  • Distinct interactions of the X-linked lymphoproliferative syndrome gene product SAP with cytoplasmic domains of members of the CD2 receptor family. 
  • Distinct mesodermal signals, including BMPs from the septum transversum mesenchyme, are required in combination for hepatogenesis from the endoderm. 
  • Distinct patterns of glycosylation of colligin, a collagen-binding glycoprotein, and SPARC (osteonectin), a secreted Ca2+-binding glycoprotein. Evidence for the localisation of colligin in the endoplasmic reticulum. 
  • Distinctive regulatory and metabolic properties of glycogen-targeting subunits of protein phosphatase-1 (PTG, GL, GM/RGl) expressed in hepatocytes. 
  • Do glucocorticoids contribute to the abnormalities in serotonin transporter expression and function seen in depression? An animal model. 
  • Domains of the adenovirus E1A protein required for oncogenic activity are also required for dissociation of E2F transcription factor complexes. 
  • Dopamine neuronal transport kinetics and effects of amphetamine. 
  • Dual protein farnesyltransferase-geranylgeranyltransferase-I inhibitors as potential cancer chemotherapeutic agents. 
  • Dual role of the exocyst in AMPA receptor targeting and insertion into the postsynaptic membrane. 
  • Dynamic actin polymerization drives T cell receptor-induced spreading: a role for the signal transduction adaptor LAT. 
  • Dynamic movements of organelles containing Niemann-Pick C1 protein: NPC1 involvement in late endocytic events. 
  • Dynamics of HIV neutralization by a microbicide formulation layer: biophysical fundamentals and transport theory. 
  • Dysferlin, annexin A1, and mitsugumin 53 are upregulated in muscular dystrophy and localize to longitudinal tubules of the T-system with stretch. 
  • Dysregulation of hedgehog signalling predisposes to synovial chondromatosis. 
  • E2F4-RB and E2F4-p107 complexes suppress gene expression by transforming growth factor beta through E2F binding sites. 
  • ERK-dependent proteasome degradation of Txnip regulates thioredoxin oxidoreductase activity. 
  • Effect of NF-kappa B inhibition on TNF-alpha-induced apoptosis in human RPE cells. 
  • Effect of limited trypsin digestion on the renal Na+-H+ exchanger and its regulation by cAMP-dependent protein kinase. 
  • Effect of oxidative stress on homer scaffolding proteins. 
  • Effects of rearrangement and allelic exclusion of JJAZ1/SUZ12 on cell proliferation and survival. 
  • Effects of titanium particle size on osteoblast functions in vitro and in vivo. 
  • Elevated plasma concentrations of alpha 1-acid glycoprotein, a putative endogenous inhibitor of the tritiated imipramine binding site, in depressed patients. 
  • Endogenous bone morphogenetic protein antagonists regulate mammalian neural crest generation and survival. 
  • Endoglin promotes transforming growth factor beta-mediated Smad 1/5/8 signaling and inhibits endothelial cell migration through its association with GIPC. 
  • Endoglin regulates PI3-kinase/Akt trafficking and signaling to alter endothelial capillary stability during angiogenesis. 
  • Energy metabolism in uncoupling protein 3 gene knockout mice. 
  • Enhanced mobilization of iron from body stores in malnourished patients during intravenous nutritional support. 
  • Epileptic spasms: a previously unreported manifestation of WDR45 gene mutation. 
  • Equatorial segment protein defines a discrete acrosomal subcompartment persisting throughout acrosomal biogenesis. 
  • Erbin is a protein concentrated at postsynaptic membranes that interacts with PSD-95. 
  • Erbin suppresses the MAP kinase pathway. 
  • Erythrocyte blood group antigens: not so simple after all. 
  • Essential role of LAT in T cell development. 
  • Ethanol exposure alters the phosphorylation of cyclic AMP responsive element binding protein and cyclic AMP responsive element binding activity in rat cerebellum. 
  • Evaluation of microsatellite instability, hMLH1 expression and hMLH1 promoter hypermethylation in defining the MSI phenotype of colorectal cancer. 
  • Evidence for a novel insulin-like growth factor (IGF)-dependent protease regulating IGF-binding protein-4 in dermal fibroblasts. 
  • Evidence for colchicine binding protein in Mycobacterium smegmatis. 
  • Evidence for positive and negative regulatory elements in the 5'-flanking sequence of the mouse sparc (osteonectin) gene. 
  • Evidence that Par-4 participates in the pathogenesis of HIV encephalitis. 
  • Ex vivo analysis of synergistic anion binding to FbpA in Gram-negative bacteria. 
  • Ex-vivo gene therapy of human vascular bypass grafts with E2F decoy: the PREVENT single-centre, randomised, controlled trial. 
  • Examining relationships between total silver concentration and Sil silver resistance genes in domestic wastewater treatment plants. 
  • Exceptional aggressiveness of cerebral cavernous malformation disease associated with PDCD10 mutations. 
  • Expression of CD44 molecules and CD44 ligands during human thymic fetal development: expression of CD44 isoforms is developmentally regulated. 
  • Expression of a peptide inhibitor of protein phosphatase 1 increases phosphorylation and activity of CREB in NIH 3T3 fibroblasts. 
  • Expression of five selected human mismatch repair genes simultaneously detected in normal and cancer cell lines by a nonradioactive multiplex reverse transcription-polymerase chain reaction. 
  • Expression of laminin isoforms, receptors, and binding proteins unique to nucleus pulposus cells of immature intervertebral disc. 
  • Expression of mRNA coding for the serotonin transporter in aged vs. young rat brain: differential effects of glucocorticoids. 
  • Expression of stimulator of Fe transport is not enhanced in Hfe knockout mice. 
  • Expression of the DMT1 (NRAMP2/DCT1) iron transporter in mice with genetic iron overload disorders. 
  • Expression of the E2F1 transcription factor overcomes type beta transforming growth factor-mediated growth suppression. 
  • Expression of the HsOrc1 gene, a human ORC1 homolog, is regulated by cell proliferation via the E2F transcription factor. 
  • Expression of the cell adhesion molecule CD44 in gastric adenocarcinomas. 
  • Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization. 
  • FK 506-binding protein proline rotamase is a target for the immunosuppressive agent FK 506 in Saccharomyces cerevisiae. 
  • FKBP12 is not required for the modulation of transforming growth factor beta receptor I signaling activity in embryonic fibroblasts and thymocytes. 
  • FKBP12 physically and functionally interacts with aspartokinase in Saccharomyces cerevisiae. 
  • FKBP12-rapamycin target TOR2 is a vacuolar protein with an associated phosphatidylinositol-4 kinase activity. 
  • FSH-induction of androgen binding protein in testes of Sertoli cell-only rats. 
  • Factors affecting Sertoli cell function in the testis. 
  • Failure of red blood cell maturation in mice with defects in the high-density lipoprotein receptor SR-BI. 
  • Failure of spermatogenesis in mouse lines deficient in the Na(+)-K(+)-2Cl(-) cotransporter. 
  • Fatty acid homeostasis and induction of lipid regulatory genes in skeletal muscles of peroxisome proliferator-activated receptor (PPAR) alpha knock-out mice. Evidence for compensatory regulation by PPAR delta. 
  • Fetal and adolescent nicotine administration: effects on CNS serotonergic systems. 
  • Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene cluster. 
  • Fine structure mapping of CIAS1: identification of an ancestral haplotype and a common FCAS mutation, L353P. 
  • Fluorescence resonance energy transfer analysis of cell surface receptor interactions and signaling using spectral variants of the green fluorescent protein. 
  • Fluoxymesterone stimulation of tumor marker secretion in patients with breast carcinoma. 
  • Folate targeting of drug carriers: a mathematical model. 
  • Frameshift intermediates in homopolymer runs are removed efficiently by yeast mismatch repair proteins. 
  • Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line. 
  • Functional genetic variants of RUVBL1 predict overall survival of Chinese patients with epithelial ovarian cancer. 
  • Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli. 
  • Functional roles of the two domains of phosducin and phosducin-like protein. 
  • Functional variants in DCAF4 associated with lung cancer risk in European populations. 
  • Functions of FKBP12 and mitochondrial cyclophilin active site residues in vitro and in vivo in Saccharomyces cerevisiae. 
  • Further studies on platelet serotonin transporter binding in depression. 
  • GIPC interacts with the beta1-adrenergic receptor and regulates beta1-adrenergic receptor-mediated ERK activation. 
  • GRIP: a synaptic PDZ domain-containing protein that interacts with AMPA receptors. 
  • Galectin-3 directs antimicrobial guanylate binding proteins to vacuoles furnished with bacterial secretion systems. 
  • Gating of CaMKII by cAMP-regulated protein phosphatase activity during LTP. 
  • Gene disruption with PCR products in Saccharomyces cerevisiae. 
  • Gene expression analysis of messenger RNP complexes. 
  • Generation of high curvature membranes mediated by direct endophilin bilayer interactions. 
  • Genes for apolipoprotein B and microsomal triglyceride transfer protein are expressed in the heart: evidence that the heart has the capacity to synthesize and secrete lipoproteins. 
  • Genes that modify the hemochromatosis phenotype in mice. 
  • Genetic Investigation Into the Differential Risk of Atrial Fibrillation Among Black and White Individuals. 
  • Genetic ablation of phosphatidylinositol transfer protein function in murine embryonic stem cells. 
  • Genetic analysis of sinonasal adenocarcinoma phenotypes: distinct alterations of histogenetic significance. 
  • Genetic diagnosis in Lafora disease: genotype-phenotype correlations and diagnostic pitfalls. 
  • Genetic effects in the leukotriene biosynthesis pathway and association with atherosclerosis. 
  • Genetic genealogy uncovers a founder deletion mutation in the cerebral cavernous malformations 2 gene. 
  • Genetic polymorphisms of selected DNA repair genes, estrogen and progesterone receptor status, and breast cancer risk. 
  • Genetic prevalence and characteristics in children with recurrent pancreatitis. 
  • Genetic variants in the TEP1 gene are associated with prostate cancer risk and recurrence. 
  • Genetic variants on chromosome 1q41 influence ocular axial length and high myopia. 
  • Genetic variation in Mon1a affects protein trafficking and modifies macrophage iron loading in mice. 
  • Genetics of cerebral cavernous malformations. 
  • Genetics. Origin of species in overdrive. 
  • Genome-wide association analyses identify three new susceptibility loci for primary angle closure glaucoma. 
  • Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder. 
  • Germline mutations in PPFIBP2 are associated with lethal prostate cancer. 
  • Global Analysis of DELLA Direct Targets in Early Gibberellin Signaling in Arabidopsis 
  • Global folds of proteins with low densities of NOEs using residual dipolar couplings: application to the 370-residue maltodextrin-binding protein. 
  • Global gene expression of Prochlorococcus ecotypes in response to changes in nitrogen availability. 
  • Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression. 
  • Glycolytic reprogramming in cancer cells: PKM2 dimer predominance induced by pulsatile PFK-1 activity. 
  • Growth arrest and DNA damage-inducible protein GADD34 assembles a novel signaling complex containing protein phosphatase 1 and inhibitor 1. 
  • Growth factor receptor-bound protein 14 undergoes light-dependent intracellular translocation in rod photoreceptors: functional role in retinal insulin receptor activation. 
  • Growth factor-mediated phosphorylation of proapoptotic BAD reduces tubule cell death in vitro and in vivo. 
  • Guanylate binding proteins enable rapid activation of canonical and noncanonical inflammasomes in Chlamydia-infected macrophages. 
  • HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibility complexes. 
  • HOXB13 G84E-related familial prostate cancers: a clinical, histologic, and molecular survey. 
  • Heat shock protein 70-binding protein 1 is highly expressed in high-grade gliomas, interacts with multiple heat shock protein 70 family members, and specifically binds brain tumor cell surfaces. 
  • Heat shock protein 90 suppresses tumor necrosis factor alpha induced apoptosis by preventing the cleavage of Bid in NIH3T3 fibroblasts. 
  • Hepatic FOXO1 Target Genes Are Co-regulated by Thyroid Hormone via RICTOR Protein Deacetylation and MTORC2-AKT Protein Inhibition. 
  • Hepatic clearance and metabolism in the rat of a human breast cancer associated glycoprotein (GCDFP-15). 
  • Hepatitis C virus directly acting antivirals: current developments with NS3/4A HCV serine protease inhibitors. 
  • Heterodimerization among thyroid hormone receptor, retinoic acid receptor, retinoid X receptor, chicken ovalbumin upstream promoter transcription factor, and an endogenous liver protein. 
  • Heterozygous variants in MYBPC1 are associated with an expanded neuromuscular phenotype beyond arthrogryposis. 
  • Hfq: a bacterial Sm-like protein that mediates RNA-RNA interaction. 
  • High affinity choline transporter status in Alzheimer's disease tissue from rapid autopsy. 
  • High frequency of aberrant p16(INK4A) expression in human breast cancer. 
  • High rate of CAD gene amplification in human cells deficient in MLH1 or MSH6. 
  • Highly variable penetrance in subjects affected with cavernous cerebral angiomas (CCM) carrying novel CCM1 and CCM2 mutations. 
  • Histologic development of the human fovea from midgestation to maturity. 
  • Home surveillance program prevents interstage mortality after the Norwood procedure. 
  • Homer modulates NFAT-dependent signaling during muscle differentiation. 
  • Homer: a protein that selectively binds metabotropic glutamate receptors. 
  • Hormonal regulation of androgen-binding protein in hypophysectomized rats. 
  • Hsp 70/Hsp 90 organizing protein as a nitrosylation target in cystic fibrosis therapy. 
  • Human adipocyte lipid-binding protein: purification of the protein and cloning of its complementary DNA. 
  • Human erythrocyte clathrin and clathrin-uncoating protein. 
  • Human galectin 3 binding protein interacts with recombinant adeno-associated virus type 6. 
  • Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf. 
  • Human immunodeficiency virus type 1 Vpr-binding protein VprBP, a WD40 protein associated with the DDB1-CUL4 E3 ubiquitin ligase, is essential for DNA replication and embryonic development. 
  • Human immunodeficiency virus. Chaperoning a pathogen. 
  • Human leukemia cell lines with comparable receptor binding characteristics but different phenotypic responses to phorbol diesters. 
  • Human platelets express endothelial protein C receptor, which can be utilized to enhance localization of factor VIIa activity. 
  • Human syngeneic intestinal transplantation: evaluation of enterocyte viability with serum levels of intestinal fatty acid binding protein. 
  • Hypertension and impaired glycine handling in mice lacking the orphan transporter XT2. 
  • Hypertrophic cardiomyopathy in cardiac myosin binding protein-C knockout mice. 
  • Hypothermic treatment restores glucose regulated protein 78 (GRP78) expression in ischemic brain. 
  • IAP proteins: sticking it to Smac. 
  • IKKα negatively regulates ASC-dependent inflammasome activation. 
  • Identification and Characterization of Proteins That Are Involved in RTP1S-Dependent Transport of Olfactory Receptors. 
  • Identification and partial purification of ankyrin, the high affinity membrane attachment site for human erythrocyte spectrin. 
  • Identification of Icm protein complexes that play distinct roles in the biogenesis of an organelle permissive for Legionella pneumophila intracellular growth. 
  • Identification of JWA as a novel functional gene responsive to environmental oxidative stress induced by benzo[a]pyrene and hydrogen peroxide. 
  • Identification of NSF as a beta-arrestin1-binding protein. Implications for beta2-adrenergic receptor regulation. 
  • Identification of a Novel Coregulator, SH3YL1, That Interacts With the Androgen Receptor N-Terminus. 
  • Identification of a chimeric emm gene and novel emm pattern in currently circulating strains of emm4 Group A Streptococcus. 
  • Identification of a putative Na(+)-H+ exchanger regulatory cofactor in rabbit renal BBM. 
  • Identification of an elaborate complex mediating postsynaptic inhibition. 
  • Identification of cellular protein phosphatase-1 regulators. 
  • Identification of cognate ligands for the Escherichia coli phnD protein product and engineering of a reagentless fluorescent biosensor for phosphonates. 
  • Identification of human and mouse p19, a novel CDK4 and CDK6 inhibitor with homology to p16ink4. 
  • Identification of myo-inositol-binding proteins by using the biotin pull-down strategy in cultured cells. 
  • Identification of phosphorylation sites in the translational regulator, PHAS-I, that are controlled by insulin and rapamycin in rat adipocytes. 
  • Identification of protein phosphatase-1-binding proteins by microcystin-biotin affinity chromatography. 
  • Identification of the endophilins (SH3p4/p8/p13) as novel binding partners for the beta1-adrenergic receptor. 
  • Identification of the human NHE-1 form of Na(+)-H+ exchanger in rabbit renal brush border membranes. 
  • Identification of transcription factors that regulate ATG8 expression and autophagy in Arabidopsis . 
  • IgG antibodies from patients with bullous pemphigoid bind to localized epitopes on synthetic peptides encoded by bullous pemphigoid antigen cDNA. 
  • Imaging genomics. 
  • Immortalized rat proximal tubule cells produce membrane bound and soluble megalin. 
  • Immune activation by histones: plusses and minuses in inflammation. 
  • Immune and Genetic Correlates of Vaccine Protection Against Mucosal Infection by SIV in Monkeys. 
  • Immunization with the Haemophilus ducreyi hemoglobin receptor HgbA with adjuvant monophosphoryl lipid A protects swine from a homologous but not a heterologous challenge. 
  • Immunohistochemical analysis of the p16INK4 cyclin-dependent kinase inhibitor in malignant mesothelioma. 
  • Immunohistochemical detection of the cyclin-dependent kinase inhibitor 2/multiple tumor suppressor gene 1 (CDKN2/MTS1) product p16INK4A in archival human solid tumors: correlation with retinoblastoma protein expression. 
  • Immunological approach to the study of hormone action: regulation of the phosphorylation state of protein phosphatase inhibitor-1 by hormones. 
  • Immunophilins interact with calcineurin in the absence of exogenous immunosuppressive ligands. 
  • Immunosuppressant target protein FKBP12 is required for P-glycoprotein function in yeast. 
  • Impaired photoreceptor protein transport and synaptic transmission in a mouse model of Bardet-Biedl syndrome. 
  • In cardiomyocyte hypoxia, insulin-like growth factor-I-induced antiapoptotic signaling requires phosphatidylinositol-3-OH-kinase-dependent and mitogen-activated protein kinase-dependent activation of the transcription factor cAMP response element-binding protein. 
  • In vitro studies on the bacteriophage P2 terminase system. 
  • In vivo dynamics of clathrin and its adaptor-dependent recruitment to the actin-based endocytic machinery in yeast. 
  • In vivo expression of mRNA for the Ca++-binding protein SPARC (osteonectin) revealed by in situ hybridization. 
  • Indian hedgehog as a progesterone-responsive factor mediating epithelial-mesenchymal interactions in the mouse uterus. 
  • Induction of protein secretory pathway is required for systemic acquired resistance. 
  • Inflammasome activation in multiple sclerosis and experimental autoimmune encephalomyelitis (EAE). 
  • Inflammasomes are important mediators of cyclophosphamide-induced bladder inflammation. 
  • Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. 
  • Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II. 
  • Inhibition of Bmp signaling affects growth and differentiation in the anagen hair follicle. 
  • Inhibition of cell proliferation by an RNA ligand that selectively blocks E2F function. 
  • Inhibition of p66ShcA longevity gene rescues podocytes from HIV-1-induced oxidative stress and apoptosis. 
  • Inhibition of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase pathway induces p53-independent transcriptional regulation of p21(WAF1/CIP1) in human prostate carcinoma cells. 
  • Inhibition of translation and induction of apoptosis by Bunyaviral nonstructural proteins bearing sequence similarity to reaper. 
  • Initiation of replication at a mammalian chromosomal origin. 
  • Innate inhibition of adaptive immunity: Mycobacterium tuberculosis-induced IL-6 inhibits macrophage responses to IFN-gamma. 
  • Insulin and diabetes cause reciprocal changes in the association of eIF-4E and PHAS-I in rat skeletal muscle. 
  • Integrated omics reveal novel functions and underlying mechanisms of the receptor kinase FERONIA in Arabidopsis thaliana. 
  • Interaction of prenylcysteine methyl esters with the multidrug resistance transporter. 
  • Interaction of the regulatory subunit (RII) of cAMP-dependent protein kinase with RII-anchoring proteins occurs through an amphipathic helix binding motif. 
  • Interactions of human mismatch repair proteins MutSalpha and MutLalpha with proteins of the ATR-Chk1 pathway. 
  • Interconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2. 
  • Interferon-β therapy against EAE is effective only when development of the disease depends on the NLRP3 inflammasome. 
  • Interim analysis of a phase I/IIa trial assessing E39+GM-CSF, a folate binding protein vaccine, to prevent recurrence in ovarian and endometrial cancer patients. 
  • Interleukin-6 and type I interferon-regulated genes and chemokines mark disease activity in dermatomyositis. 
  • Intravascular bronchioloalveolar tumor of the lung presenting as pulmonary thromboembolic disease and pulmonary hypertension. 
  • Involvement of a calcineurin/inhibitor-1 phosphatase cascade in hippocampal long-term depression. 
  • Involvement of linker for activation of T cells in the costimulatory signaling pathways. 
  • Iodopyridine-for-iodobenzene substitution for use with low molecular weight radiopharmaceuticals: application to m-iodobenzylguanidine. 
  • Ion fluxes and differentiation in transformed cell lines. 
  • Iron is hot: an update on the pathophysiology of hemochromatosis. 
  • Iron transport across biologic membranes. 
  • Is there protective haplotype of dysbindin gene (DTNBP1) 3 polymorphisms for major depressive disorder. 
  • Isolation and characterization of point mutations in mismatch repair genes that destabilize microsatellites in yeast. 
  • Isolation and characterization of renal cortical membranes using an aqueous two-phase partition technique. 
  • Isolation and initial characterization of the BRCA2 promoter. 
  • Isolation and regulation of the protein kinase inhibitor and the calcium-dependent cyclic nucleotide phosphodiesterase regulator in the Sertoli cell-enriched testis. 
  • Isolation of retinal proteins that interact with retinitis pigmentosa GTPase regulator by interaction trap screen in yeast. 
  • Isolation, purification and characterization of an iron-binding protein from the horseshoe crab (Limulus polyphemus). 
  • Just say NO to NLRP3. 
  • KRIT1 association with the integrin-binding protein ICAP-1: a new direction in the elucidation of cerebral cavernous malformations (CCM1) pathogenesis. 
  • Knock-in mutation of the distal four tyrosines of linker for activation of T cells blocks murine T cell development. 
  • LAB: a new membrane-associated adaptor molecule in B cell activation. 
  • LAT is essential for Fc(epsilon)RI-mediated mast cell activation. 
  • LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway. 
  • LAT is required for tyrosine phosphorylation of phospholipase cgamma2 and platelet activation by the collagen receptor GPVI. 
  • LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation. 
  • LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation. 
  • LPS-aggregating proteins GBP1 and GBP2 are each sufficient to enhance caspase-4 activation both in cellulo and in vitro. 
  • LRRK2 and Rab10 coordinate macropinocytosis to mediate immunological responses in phagocytes. 
  • Lack of association between UBQLN1 and Alzheimer disease. 
  • Lack of association between primary angle-closure glaucoma susceptibility loci and the ocular biometric parameters anterior chamber depth and axial length. 
  • Lack of utility of intestinal fatty acid binding protein levels in predicting intestinal allograft rejection. 
  • Lactic acidosis triggers starvation response with paradoxical induction of TXNIP through MondoA. 
  • Learning new tricks from old dogs: beta-adrenergic receptors teach new lessons on firing up adipose tissue metabolism. 
  • Leptin regulates proinflammatory immune responses. 
  • Lesions from patients with sporadic cerebral cavernous malformations harbor somatic mutations in the CCM genes: evidence for a common biochemical pathway for CCM pathogenesis. 
  • Linker for activation of B cells: a functional equivalent of a mutant linker for activation of T cells deficient in phospholipase C-gamma1 binding. 
  • Linker for activation of T cells (LAT), a novel immunohistochemical marker for T cells, NK cells, mast cells, and megakaryocytes: evaluation in normal and pathological conditions. 
  • Lipopolysaccharide induces oxidative cardiac mitochondrial damage and biogenesis. 
  • Lis1 is essential for cortical microtubule organization and desmosome stability in the epidermis. 
  • Localization of DIR1 at the tissue, cellular and subcellular levels during Systemic Acquired Resistance in Arabidopsis using DIR1:GUS and DIR1:EGFP reporters. 
  • Localization of a domain in the FimH adhesin of Escherichia coli type 1 fimbriae capable of receptor recognition and use of a domain-specific antibody to confer protection against experimental urinary tract infection. 
  • Long-term stabilization of vein graft wall architecture and prolonged resistance to experimental atherosclerosis after E2F decoy oligonucleotide gene therapy. 
  • Loss of NR1 subunit of NMDARs in primary sensory neurons leads to hyperexcitability and pain hypersensitivity: involvement of Ca(2+)-activated small conductance potassium channels. 
  • Loss of RB and MTS1/CDKN2 (p16) expression in human sarcomas. 
  • Loss of pyruvate kinase M2 limits growth and triggers innate immune signaling in endothelial cells. 
  • Low frequency of PDCD10 mutations in a panel of CCM3 probands: potential for a fourth CCM locus. 
  • Luminal CCK-releasing factor stimulates CCK release from human intestinal endocrine and STC-1 cells. 
  • MARCH2 promotes endocytosis and lysosomal sorting of carvedilol-bound β(2)-adrenergic receptors. 
  • MOP2 (SLA2) affects the abundance of the plasma membrane H(+)-ATPase of Saccharomyces cerevisiae. 
  • Male germ cells and photoreceptors, both dependent on close cell-cell interactions, degenerate upon ClC-2 Cl(-) channel disruption. 
  • Mammalian RAFT1 kinase domain provides rapamycin-sensitive TOR function in yeast. 
  • Mammalian iron transport: an unexpected link between metal homeostasis and host defense. 
  • Manipulation of ligand binding affinity by exploitation of conformational coupling. 
  • Mapping the ankyrin-binding site of the human erythrocyte anion exchanger. 
  • Mapping the binding sites of human erythrocyte ankyrin for the anion exchanger and spectrin. 
  • Marked reduction in the number of platelet-tritiated imipramine binding sites in geriatric depression. 
  • Measurement of fat/water ratios in rat liver using 3D three-point dixon MRI. 
  • Mechanism of inactivation of CDKN2 and MTS2 in non-small cell lung cancer and association with advanced stage. 
  • Mechanisms of NOD-like receptor-associated inflammasome activation. 
  • Megalin/Cubulin-Lysosome-mediated Albumin Reabsorption Is Involved in the Tubular Cell Activation of NLRP3 Inflammasome and Tubulointerstitial Inflammation. 
  • Meta-analysis of 2040 sickle cell anemia patients: BCL11A and HBS1L-MYB are the major modifiers of HbF in African Americans. 
  • Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia. 
  • Methionine motifs of copper transport proteins provide general and flexible thioether-only binding sites for Cu(I) and Ag(I). 
  • Mice lacking Homer 1 exhibit a skeletal myopathy characterized by abnormal transient receptor potential channel activity. 
  • Mice lacking the dopamine transporter display altered regulation of distal colonic motility. 
  • Mice lacking the norepinephrine transporter are supersensitive to psychostimulants. 
  • Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene. 
  • Mimosine targets serine hydroxymethyltransferase. 
  • Mimosine, a novel inhibitor of DNA replication, binds to a 50 kDa protein in Chinese hamster cells. 
  • Minimal requirement of tyrosine residues of linker for activation of T cells in TCR signaling and thymocyte development. 
  • Mining copper transport genes. 
  • Mitochondrial uncoupling: role of uncoupling protein anion carriers and relationship to thermogenesis and weight control "the benefits of losing control". 
  • Modeling geriatric depression in animals: biochemical and behavioral effects of olfactory bulbectomy in young versus aged rats. 
  • Modulation of BMP signaling by Noggin is required for the maintenance of palatal epithelial integrity during palatogenesis. 
  • Modulation of ligand binding affinity of the adipocyte lipid-binding protein by selective mutation. Analysis in vitro and in situ. 
  • Molecular analysis of P16(Ink4)/CDKN2 and P15(INK4B)/MTS2 genes in primary human testicular germ cell tumors. 
  • Molecular analysis of the cDNA for human SPARC/osteonectin/BM-40: sequence, expression, and localization of the gene to chromosome 5q31-q33. 
  • Molecular characterization of adenocarcinoma of the cervix. 
  • Molecular cloning of protein phosphatase inhibitor-1 and its expression in rat and rabbit tissues. 
  • Molecular cloning, expression and functional characterization of rabbit anticoagulant vitamin-K-dependent protein S. 
  • Molecular determinants of nuclear protein phosphatase-1 regulation by NIPP-1. 
  • Molecular determinants of sensitivity to antitumor agents. 
  • Molecular genetic analysis of two human sperm fibrous sheath proteins, AKAP4 and AKAP3, in men with dysplasia of the fibrous sheath. 
  • Molecular genetic parameters in pathogenesis and prognosis of testicular germ cell tumors. 
  • Molecular insights into mechanisms of iron transport. 
  • Molecular mechanism by which the nucleoid occlusion factor, SlmA, keeps cytokinesis in check. 
  • Molecular mechanisms of immunosuppression by cyclosporine, FK506, and rapamycin. 
  • Molecular symmetry as an aid to geometry determination in ligand protein complexes. 
  • Monoclonal antibodies that bind to the core of fusion-active glycoprotein 41. 
  • Monocyte adhesion in patients with bone marrow fibrosis is required for the production of fibrogenic cytokines. Potential role for interleukin-1 and TGF-beta. 
  • Morphogenesis of the trachea and esophagus: current players and new roles for noggin and Bmps. 
  • Mouse retinal pigmented epithelial cell lines retain their phenotypic characteristics after transfection with human papilloma virus: a new tool to further the study of RPE biology. 
  • Multiple Nod-like receptors activate caspase 1 during Listeria monocytogenes infection. 
  • Multiple Surface Regions on the Niemann-Pick C2 Protein Facilitate Intracellular Cholesterol Transport. 
  • Multiple interactions within the AKAP220 signaling complex contribute to protein phosphatase 1 regulation. 
  • Multiple mechanisms control phosphorylation of PHAS-I in five (S/T)P sites that govern translational repression. 
  • Multiple pathways of rapid beta 2-adrenergic receptor desensitization. Delineation with specific inhibitors. 
  • Multiple structural elements define the specificity of recombinant human inhibitor-1 as a protein phosphatase-1 inhibitor. 
  • Multiple tissue-specific requirements for the BMP antagonist Noggin in development of the mammalian craniofacial skeleton. 
  • Mutational analysis of ATP7B and genotype-phenotype correlation in Japanese with Wilson's disease. 
  • Mutational analysis of potential zinc-binding residues in the active site of the enterococcal D-Ala-D-Ala dipeptidase VanX. 
  • Mutational analysis of the coding regions of the genes encoding protein kinase B-alpha and -beta, phosphoinositide-dependent protein kinase-1, phosphatase targeting to glycogen, protein phosphatase inhibitor-1, and glycogenin: lessons from a search for genetic variability of the insulin-stimulated glycogen synthesis pathway of skeletal muscle in NIDDM patients. 
  • Mutations in SCO2 are associated with autosomal-dominant high-grade myopia. 
  • Mutations in SLC19A2 cause thiamine-responsive megaloblastic anaemia associated with diabetes mellitus and deafness. 
  • Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities. 
  • Mutations of the p16 gene product are rare in prostate cancer. 
  • Mutations of the serine phosphorylated in the protein phosphatase-1-binding motif in the skeletal muscle glycogen-targeting subunit. 
  • Mutations that perturb cyclophilin A ligand binding pocket confer cyclosporin A resistance in Saccharomyces cerevisiae. 
  • Mycobacterium tuberculosis Evasion of Guanylate Binding Protein-Mediated Host Defense in Mice Requires the ESX1 Secretion System. 
  • Myristoylation of calcineurin B is not required for function or interaction with immunophilin-immunosuppressant complexes in the yeast Saccharomyces cerevisiae. 
  • NLRC4 and TLR5 each contribute to host defense in respiratory melioidosis. 
  • NLRP3 inflammasome induces chemotactic immune cell migration to the CNS in experimental autoimmune encephalomyelitis. 
  • NMR structural characterization of the CDK inhibitor p19INK4d. 
  • Nanostring-based multigene assay to predict recurrence for gastric cancer patients after surgery. 
  • Native recombinant cyclophilins A, B, and C degrade DNA independently of peptidylprolyl cis-trans-isomerase activity. Potential roles of cyclophilins in apoptosis. 
  • Nedd4 mediates agonist-dependent ubiquitination, lysosomal targeting, and degradation of the beta2-adrenergic receptor. 
  • Neisseria gonorrhoeae FitA interacts with FitB to bind DNA through its ribbon-helix-helix motif. 
  • Neural grafting reverses prenatal drug-induced alterations in hippocampal PKC and related behavioral deficits. 
  • Neural plate morphogenesis during mouse neurulation is regulated by antagonism of Bmp signalling. 
  • Neutrophil gelatinase-associated lipocalin in normal and neoplastic human tissues. Cell type-specific pattern of expression. 
  • New lessons in the regulation of glucose metabolism taught by the glucose 6-phosphatase system. 
  • Niche-mediated BMP/SMAD signaling regulates lung alveolar stem cell proliferation and differentiation. 
  • Nitric oxide represses the Arabidopsis floral transition. 
  • Nomenclature: vertebrate mediators of TGFbeta family signals. 
  • Novel Genetic Triggers and Genotype-Phenotype Correlations in Patients With Left Ventricular Noncompaction. 
  • Novel PMS1 alleles preferentially affect the repair of primer strand loops during DNA replication. 
  • Novel function of clathrin light chain in promoting endocytic vesicle formation. 
  • Nramp2 is mutated in the anemic Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport. 
  • Nuclear RNA-binding proteins. 
  • Nucleotide receptors regulate membrane ion transport in renal epithelial cells. 
  • Nup358, a cytoplasmically exposed nucleoporin with peptide repeats, Ran-GTP binding sites, zinc fingers, a cyclophilin A homologous domain, and a leucine-rich region. 
  • Nutritional regulation of insulin-like growth factor-binding protein gene expression in the ovine fetus and pregnant ewe. 
  • O (4)-benzylfolic acid inactivates O (6)-alkylguanine-DNA alkyltransferase in brain tumor cell lines. 
  • OB-Rb gene transfer to leptin-resistant islets reverses diabetogenic phenotype. 
  • Obscurin interacts with a novel isoform of MyBP-C slow at the periphery of the sarcomeric M-band and regulates thick filament assembly. 
  • Olfactory receptor accessory proteins play crucial roles in receptor function and gene choice. 
  • Oligomeric structure and tissue distribution of ficolins from mouse, pig and human. 
  • Overexpression of a Drosophila homolog of apolipoprotein D leads to increased stress resistance and extended lifespan. 
  • Overexpression of folate binding protein and mesothelin are associated with uterine serous carcinoma. 
  • Overexpression of folate binding protein is associated with shortened progression-free survival in uterine adenocarcinomas. 
  • Overexpression of leptin receptors in pancreatic islets of Zucker diabetic fatty rats restores GLUT-2, glucokinase, and glucose-stimulated insulin secretion. 
  • Overexpression of the glucose-regulated stress gene GRP78 in malignant but not benign human breast lesions. 
  • Overexpression of the high affinity choline transporter in cortical regions affected by Alzheimer's disease. Evidence from rapid autopsy studies. 
  • PGC-1 coactivators regulate MITF and the tanning response. 
  • PHAS proteins as mediators of the actions of insulin, growth factors and cAMP on protein synthesis and cell proliferation. 
  • PHAS-I as a link between mitogen-activated protein kinase and translation initiation. 
  • PI3K/mTOR Dual Inhibitor, LY3023414, Demonstrates Potent Antitumor Efficacy Against Esophageal Adenocarcinoma in a Rat Model. 
  • PKM1 Exerts Critical Roles in Cardiac Remodeling Under Pressure Overload in the Heart. 
  • PRCD Is a Small Disc-Specific Rhodopsin-Binding Protein of Unknown Function. 
  • Parc-ing p53 in the cytoplasm. 
  • Parkin is not regulated by the unfolded protein response in human neuroblastoma cells. 
  • Participation of ATM in insulin signalling through phosphorylation of eIF-4E-binding protein 1. 
  • Participation of c-FLIP in NLRP3 and AIM2 inflammasome activation. 
  • Pathophysiology of SPINK mutations in pancreatic development and disease. 
  • Patients with X-linked lymphoproliferative disease have a defect in 2B4 receptor-mediated NK cell cytotoxicity. 
  • Pbp1-Interacting Protein Mkt1 Regulates Virulence and Sexual Reproduction in Cryptococcus neoformans. 
  • Peptidoglycan-Sensing Receptors Trigger the Formation of Functional Amyloids of the Adaptor Protein Imd to Initiate Drosophila NF-κB Signaling. 
  • Persistent cholinergic presynaptic deficits after neonatal chlorpyrifos exposure. 
  • Perturbed length-dependent activation in human hypertrophic cardiomyopathy with missense sarcomeric gene mutations. 
  • Phase II and pharmacodynamic study of the farnesyltransferase inhibitor R115777 as initial therapy in patients with metastatic pancreatic adenocarcinoma. 
  • Phorbol diester-induced H2O2 production by peritoneal macrophages. Different H2O2 production by macrophages from normal and BCG-infected mice despite comparable phorbol diester receptors. 
  • Phorbol esters induce differentiation in a pre-B-lymphocyte cell line by enhancing Na+/H+ exchange. 
  • Phosphatase and tensin homolog (PTEN) regulates hepatic lipogenesis, microsomal triglyceride transfer protein, and the secretion of apolipoprotein B-containing lipoproteins. 
  • Phosphate ester hydrolysis is catalyzed by a bacterial transferrin: potential implications for in vivo iron transport mechanisms. 
  • Phosphatidylcholine transfer protein promotes apolipoprotein A-I-mediated lipid efflux in Chinese hamster ovary cells. 
  • Phosphoinositide 3-kinase regulates beta2-adrenergic receptor endocytosis by AP-2 recruitment to the receptor/beta-arrestin complex. 
  • Phospholipid-binding protein Cts1 controls septation and functions coordinately with calcineurin in Cryptococcus neoformans. 
  • Phosphoproteome analysis of capacitated human sperm. Evidence of tyrosine phosphorylation of a kinase-anchoring protein 3 and valosin-containing protein/p97 during capacitation. 
  • Phosphorylation of 4E-BP1 in the mammalian brain is not altered by LRRK2 expression or pathogenic mutations. 
  • Phosphorylation of PHAS-I by mitogen-activated protein (MAP) kinase. Identification of a site phosphorylated by MAP kinase in vitro and in response to insulin in rat adipocytes. 
  • Phosphorylation of the translational regulator, PHAS-I, by protein kinase CK2. 
  • Phylogeny of Toll-like receptor signaling: adapting the innate response. 
  • Physiologic importance of protein phosphatase inhibitors. 
  • Platelet [3H]-imipramine binding and leukoencephalopathy in geriatric depression. 
  • Pleiotrophin mediates hematopoietic regeneration via activation of RAS. 
  • Pleiotrophin regulates the ductular reaction by controlling the migration of cells in liver progenitor niches. 
  • Pleiotrophin regulates the expansion and regeneration of hematopoietic stem cells. 
  • Pleiotrophin regulates the retention and self-renewal of hematopoietic stem cells in the bone marrow vascular niche. 
  • Pleiotropic alterations in lipid metabolism in yeast sac1 mutants: relationship to "bypass Sec14p" and inositol auxotrophy. 
  • Polymorphisms of CAK genes and risk for lung cancer: a case-control study in Chinese population. 
  • Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter. 
  • Post-translational Regulation of FNIP1 Creates a Rheostat for the Molecular Chaperone Hsp90. 
  • Post-translational regulation of calsarcin-1 during pressure overload-induced cardiac hypertrophy. 
  • Postsynaptic positioning of endocytic zones and AMPA receptor cycling by physical coupling of dynamin-3 to Homer. 
  • Potential pathogenicity of deglycosylated IgG cross reactive with streptokinase and fibronectin in the serum of patients with rheumatoid arthritis. 
  • Potentially functional genetic variants in the TNF/TNFR signaling pathway genes predict survival of patients with non-small cell lung cancer in the PLCO cancer screening trial. 
  • Potentiation of CD3-induced expression of the linker for activation of T cells (LAT) by the calcineurin inhibitors cyclosporin A and FK506. 
  • Potentiation of progesterone receptor-mediated transcription by the immunosuppressant FK506. 
  • Prenylated peptides in identification of specific binding proteins. 
  • Preparation of peptide-loaded dendritic cells for cancer immunotherapy. 
  • Prevention of brefeldin A-induced resistance to teniposide by the proteasome inhibitor MG-132: involvement of NF-kappaB activation in drug resistance. 
  • Primer-BLAST: a tool to design target-specific primers for polymerase chain reaction. 
  • Probing the interaction of the multidrug-resistance phenotype with the polypeptide ionophore gramicidin D via functional channel formation. 
  • Programming of brainstem serotonin transporter development by prenatal glucocorticoids. 
  • Proline isomerases at the crossroads of protein folding, signal transduction, and immunosuppression. 
  • Proline isomerases in microorganisms and small eukaryotes. 
  • Proteasome-mediated turnover of the transcription coactivator NPR1 plays dual roles in regulating plant immunity. 
  • Protection against lipoapoptosis of beta cells through leptin-dependent maintenance of Bcl-2 expression. 
  • Protein (serine and threonine) phosphate phosphatases. 
  • Protein kinase C activates the renal apical membrane Na+/H+ exchanger. 
  • Protein kinase activity and identification of a toxic effector domain of the target of rapamycin TOR proteins in yeast. 
  • Protein kinase activity of Tel1p and Mec1p, two Saccharomyces cerevisiae proteins related to the human ATM protein kinase. 
  • Protein kinase inhibitor in sertoli cell-enriched rat testis. Specific regulation by follicle-stimulating hormone. 
  • Protein loop closure using orientational restraints from NMR data. 
  • Protein phosphatase 2A activates the proapoptotic function of BAD in interleukin- 3-dependent lymphoid cells by a mechanism requiring 14-3-3 dissociation. 
  • Protein phosphatase 2A dephosphorylation of phosphoserine 112 plays the gatekeeper role for BAD-mediated apoptosis. 
  • Protein phosphatase regulation by endogenous inhibitors. 
  • Protein tyrosine kinase 6 negatively regulates growth and promotes enterocyte differentiation in the small intestine. 
  • Protein/AS01B vaccination elicits stronger, more Th2-skewed antigen-specific human T follicular helper cell responses than heterologous viral vectors. 
  • Proteomic analysis of the luteal endometrial secretome. 
  • Purification of a 12,020-dalton protein that enhances the activation of mitogen-activated protein (MAP) kinase by MAP kinase kinase. 
  • Quantitation of response to therapy in patients with metastatic breast carcinoma by serial analysis of plasma gross cystic disease fluid protein and carcinoembryonic antigen. 
  • R73A and H144Q mutants of the yeast mitochondrial cyclophilin Cpr3 exhibit a low prolyl isomerase activity in both peptide and protein-folding assays. 
  • RANK, RANKL, OPG, and M-CSF expression in stromal cells during corneal wound healing. 
  • RBM45 is an m6A-binding protein that affects neuronal differentiation and the splicing of a subset of mRNAs. 
  • RNA recognition: towards identifying determinants of specificity. 
  • RNA-binding protein FXR2 regulates adult hippocampal neurogenesis by reducing Noggin expression. 
  • RPGR isoforms in photoreceptor connecting cilia and the transitional zone of motile cilia. 
  • Rabbit plasma, unlike its human counterpart, contains no complex between protein S and C4b-binding protein. 
  • Rabbits immunized with a peptide encoded for by the 230-kD bullous pemphigoid antigen cDNA develop an enhanced inflammatory response to UVB irradiation: a potential animal model for bullous pemphigoid. 
  • Randomized, Double-Blind, Placebo-Controlled Trial of the Effect of Vitamin D3 on the Interferon Signature in Patients With Systemic Lupus Erythematosus. 
  • Rapamycin and p53 act on different pathways to induce G1 arrest in mammalian cells. 
  • Rapamycin antagonizes cyclosporin A- and tacrolimus (FK506)-mediated augmentation of linker for activation of T cell expression in T cells. 
  • Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells. 
  • Rapid assembly dynamics of the Escherichia coli FtsZ-ring demonstrated by fluorescence recovery after photobleaching. 
  • Rapid identification of protein phosphatase 1-binding proteins by mixed peptide sequencing and data base searching. Characterization of a novel holoenzymic form of protein phosphatase 1. 
  • Rb and p16INK4a expression in resected non-small cell lung tumors. 
  • Reaper-induced dissociation of a Scythe-sequestered cytochrome c-releasing activity. 
  • Receptor-mediated modulation of human monocyte, neutrophil, lymphocyte, and platelet function by phorbol diesters. 
  • Receptor-recognized α₂-macroglobulin binds to cell surface-associated GRP78 and activates mTORC1 and mTORC2 signaling in prostate cancer cells. 
  • Recognition of multiple drugs by a single protein: a trivial solution of an old paradox. 
  • Reconstitution of cAMP-dependent protein kinase regulated renal Na+-H+ exchanger. 
  • Reconstitution of protein translocation from detergent-solubilized Escherichia coli inverted vesicles: PrlA protein-deficient vesicles efficiently translocate precursor proteins. 
  • Reduced dermatopontin expression is a molecular link between uterine leiomyomas and keloids. 
  • Reduced expression of hMLH1 and hGTBP/hMSH6: a risk factor for head and neck cancer. 
  • Reduced expression of hMSH2 and hMLH1 and risk of prostate cancer: a case-control study. 
  • Reduced expression of mismatch repair genes in colorectal cancer patients in Egypt. 
  • Reduced expression of mismatch repair genes measured by multiplex reverse transcription-polymerase chain reaction in human gliomas. 
  • Reduced inhibitory effect of imipramine on radiolabeled serotonin uptake into platelets in geriatric depression. 
  • Regulation and localization of the insulin-like growth factor system in small bowel during altered nutrient status. 
  • Regulation of cell-cell adhesion by Abi/Diaphanous complexes. 
  • Regulation of cholecystokinin secretion by intraluminal releasing factors. 
  • Regulation of membrane targeting of the G protein-coupled receptor kinase 2 by protein kinase A and its anchoring protein AKAP79. 
  • Regulation of microfilaments and microtubules by calcium and cyclic AMP. 
  • Regulation of reconstituted renal Na+/H+ exchanger by calcium-dependent protein kinases. 
  • Regulation of renal Na(+)-H+ exchanger by cAMP-dependent protein kinase. 
  • Regulation of the renal Na(+)-H+ exchanger by calcium calmodulin-dependent multifunctional protein kinase II. 
  • Regulation of the renal Na+-H+ exchanger by protein phosphorylation. 
  • Regulation of the renal brush border membrane Na(+)-H+ exchanger. 
  • Regulation of the uncoupling protein gene (Ucp) by beta 1, beta 2, and beta 3-adrenergic receptor subtypes in immortalized brown adipose cell lines. 
  • Regulators of pseudohyphal differentiation in Saccharomyces cerevisiae identified through multicopy suppressor analysis in ammonium permease mutant strains. 
  • Regulatory and structural motifs of chicken gizzard myosin light chain kinase. 
  • Reichert's membrane as a model for studying the biosynthesis and assembly of basement membrane components. 
  • Relationship between serotonin transporter gene polymorphisms and platelet serotonin transporter sites among African-American cocaine-dependent individuals and healthy volunteers. 
  • Removal of frameshift intermediates by mismatch repair proteins in Saccharomyces cerevisiae. 
  • Repair versus Checkpoint Functions of BRCA1 Are Differentially Regulated by Site of Chromatin Binding. 
  • Repurposing an endogenous degradation system for rapid and targeted depletion of C. elegans proteins. 
  • Requirement for Abl kinases in T cell receptor signaling. 
  • Residual dipolar coupling derived orientational constraints on ligand geometry in a 53 kDa protein-ligand complex. 
  • Restoration of hepatic glucokinase expression corrects hepatic glucose flux and normalizes plasma glucose in zucker diabetic fatty rats. 
  • Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs. 
  • Retention of pendrin in the endoplasmic reticulum is a major mechanism for Pendred syndrome. 
  • Retina-specifically expressed novel subtypes of bovine cyclophilin. 
  • Retinoic acid receptor expression vector inhibits differentiation of F9 embryonal carcinoma cells. 
  • Retinoic acid receptors: transcription factors modulating gene regulation, development, and differentiation. 
  • Reversible inhibition of Hsp70 chaperone function by Scythe and Reaper. 
  • Rh-related antigen CD47 is the signal-transducer integrin-associated protein. 
  • Rig1 receptor plays a critical role in cardiac reprogramming via YY1 signaling. 
  • Right ventricular gene therapy with a beta-adrenergic receptor kinase inhibitor improves survival after pulmonary artery banding. 
  • Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis. 
  • Role of autophagy genetic variants for the risk of Candida infections. 
  • Role of c-Src tyrosine kinase in G protein-coupled receptor- and Gbetagamma subunit-mediated activation of mitogen-activated protein kinases. 
  • Role of enzyme-bound 5,10-methenyltetrahydropteroylpolyglutamate in catalysis by Escherichia coli DNA photolyase. 
  • Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity. 
  • Role of vasorin, an anti-apoptotic, anti-TGF-β and hypoxia-induced glycoprotein in the trabecular meshwork cells and glaucoma. 
  • Roles for Ndel1 in keratin organization and desmosome function. 
  • Roles of bone morphogenetic protein signaling and its antagonism in holoprosencephaly. 
  • Roles of organizer factors and BMP antagonism in mammalian forebrain establishment. 
  • S-adenosylhomocysteine hydrolase is an adenosine-binding protein: a target for adenosine toxicity. 
  • SNIP1 inhibits NF-kappa B signaling by competing for its binding to the C/H1 domain of CBP/p300 transcriptional co-activators. 
  • STRIP1, a core component of STRIPAK complexes, is essential for normal mesoderm migration in the mouse embryo. 
  • Scavenger receptor BI attenuates oxidized phospholipid-induced pulmonary inflammation. 
  • Scd5p and clathrin function are important for cortical actin organization, endocytosis, and localization of sla2p in yeast. 
  • Screen and identification of proteins interacting with ADAM19 cytoplasmic tail. 
  • Scythe: a novel reaper-binding apoptotic regulator. 
  • Select de novo gene and protein expression during renal epithelial cell culture in rotating wall vessels is shear stress dependent. 
  • Selective activation of mitogen-activated protein (MAP) kinase kinase 3 and p38alpha MAP kinase is essential for cyclic AMP-dependent UCP1 expression in adipocytes. 
  • Selective externalization of an ATP-binding protein structurally related to the clathrin-uncoating ATPase/heat shock protein in vesicles containing terminal transferrin receptors during reticulocyte maturation. 
  • Selective glutamine metabolism inhibition in tumor cells improves antitumor T lymphocyte activity in triple-negative breast cancer. 
  • Selective loss of RPGRIP1-dependent ciliary targeting of NPHP4, RPGR and SDCCAG8 underlies the degeneration of photoreceptor neurons. 
  • Selective phosphorylation of PKA targets after β-adrenergic receptor stimulation impairs myofilament function in Mybpc3-targeted HCM mouse model. 
  • Selenium-binding protein-1 in smooth muscle cells is downregulated in a rhesus monkey model of chronic allograft nephropathy. 
  • Sensing heart stress. 
  • Separation and quantitation of serum constituents associated with calcium by gel filtration. 
  • Sequence homology of the Ca2+-dependent regulator of cyclic nucleotide phosphodiesterase from rat testis with other Ca2+-binding proteins. 
  • Serotonergic systems targeted by developmental exposure to chlorpyrifos: effects during different critical periods. 
  • Serotonin transporter expression in rat brain regions and blood platelets: aging and glucocorticoid effects. 
  • Serotonin transporter genetic variation and the response of the human amygdala. 
  • Serotonin-related gene polymorphisms and central nervous system serotonin function. 
  • Shank3 mutant mice display autistic-like behaviours and striatal dysfunction. 
  • Signaling via LAT (linker for T-cell activation) and Syk/ZAP70 is required for ERK activation and NFAT transcriptional activation following CD2 stimulation. 
  • SlmA forms a higher-order structure on DNA that inhibits cytokinetic Z-ring formation over the nucleoid. 
  • Smac/Diablo antagonizes ubiquitin ligase activity of inhibitor of apoptosis proteins. 
  • Small contribution of G1 checkpoint control manipulation to modulation of p53-mediated apoptosis. 
  • Solubilization and reconstitution of renal brush border Na+-H+ exchanger. 
  • Somatic mutation of hPMS2 as a possible cause of sporadic human colon cancer with microsatellite instability. 
  • Sorting nexin homologues are targets of phosphatidylinositol 3-phosphate in sporulation of Schizosaccharomyces pombe. 
  • Species-specific subcellular localization of RPGR and RPGRIP isoforms: implications for the phenotypic variability of congenital retinopathies among species. 
  • Specific nuclear binding of adenosine 3',5'-monophosphate-binding protein complex with subsequent poly(A) RNA synthesis in embryonic chick cartilage. 
  • Specific receptors for phorbol diesters on freshly isolated human myeloid and lymphoid leukemia cells: comparable binding characteristics despite different cellular responses. 
  • Staphylococcus aureus evades lysozyme-based peptidoglycan digestion that links phagocytosis, inflammasome activation, and IL-1beta secretion. 
  • Stathmin-deficient mice develop an age-dependent axonopathy of the central and peripheral nervous systems. 
  • Steroid-sensitive nephrotic syndrome candidate gene CLVS1 regulates podocyte oxidative stress and endocytosis. 
  • Stimulation of secretion by the T84 colonic epithelial cell line with dietary flavonols. 
  • Stimulation of the T3-T cell receptor-associated Ca2+ influx enhances the activity of the Na+/H+ exchanger in a leukemic human T cell line. 
  • Strain-specific response to beta 3-adrenergic receptor agonist treatment of diet-induced obesity in mice. 
  • Structural adaptations that modulate monosaccharide, disaccharide, and trisaccharide specificities in periplasmic maltose-binding proteins. 
  • Structural analysis of semi-specific oligosaccharide recognition by a cellulose-binding protein of thermotoga maritima reveals adaptations for functional diversification of the oligopeptide periplasmic binding protein fold. 
  • Structural analysis of the purine repressor, an Escherichia coli DNA-binding protein. 
  • Structural basis for SH2D1A mutations in X-linked lymphoproliferative disease. 
  • Structural evidence that the P/Q domain of ZipA is an unstructured, flexible tether between the membrane and the C-terminal FtsZ-binding domain. 
  • Structure of FitAB from Neisseria gonorrhoeae bound to DNA reveals a tetramer of toxin-antitoxin heterodimers containing pin domains and ribbon-helix-helix motifs. 
  • Structure of human Niemann-Pick C1 protein. 
  • Structure of the SHR-SCR heterodimer bound to the BIRD/IDD transcriptional factor JKD. 
  • Structure of the Trypanosoma brucei p22 protein, a cytochrome oxidase subunit II-specific RNA-editing accessory factor. 
  • Structure-based design of robust glucose biosensors using a Thermotoga maritima periplasmic glucose-binding protein. 
  • Structures of the nucleoid occlusion protein SlmA bound to DNA and the C-terminal domain of the cytoskeletal protein FtsZ. 
  • Structures of the pleiotropic translational regulator Hfq and an Hfq-RNA complex: a bacterial Sm-like protein. 
  • Structures of yeast vesicle trafficking proteins. 
  • Studies on the adapter molecule LAT. 
  • Studies on the interaction between TWEAK and the death receptor WSL-1/TRAMP (DR3). 
  • Subgroup-specific structural variation across 1,000 medulloblastoma genomes. 
  • Substituted 2,2-bisaryl-bicycloheptanes as novel and potent inhibitors of 5-lipoxygenase activating protein. 
  • Substituted indoles as potent and orally active 5-lipoxygenase activating protein (FLAP) inhibitors. 
  • Substrate availability and transcriptional regulation of metabolic genes in human skeletal muscle during recovery from exercise. 
  • Suppressor and activator functions mediated by a repeated heptad sequence in the liver fatty acid-binding protein gene (Fabpl). Effects on renal, small intestinal, and colonic epithelial cell gene expression in transgenic mice. 
  • Synaptic activation of presynaptic glutamate transporter currents in nerve terminals. 
  • Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3. 
  • Synaptically targeted narp plays an essential role in the aggregation of AMPA receptors at excitatory synapses in cultured spinal neurons. 
  • Synchronous primary perianal Paget's disease and rectal adenocarcinoma: report of a hitherto undescribed phenomenon. 
  • Synthesis and characterization of a ruthenium(II)-based redox conjugate for reagentless biosensing. 
  • Systemic inflammatory response syndrome after human syngeneic intestinal transplantation: evidence for disruption of enterocyte barrier function. 
  • TOR mutations confer rapamycin resistance by preventing interaction with FKBP12-rapamycin. 
  • TRPC1 channels are critical for hypertrophic signaling in the heart. 
  • TXNIP links redox circuitry to glucose control. 
  • Tamoxifen for early breast cancer: an overview of the randomised trials. Early Breast Cancer Trialists' Collaborative Group. 
  • Targeted beta-adrenergic receptor kinase (betaARK1) inhibition by gene transfer in failing human hearts. 
  • Targeted metabolomics connects thioredoxin-interacting protein (TXNIP) to mitochondrial fuel selection and regulation of specific oxidoreductase enzymes in skeletal muscle. 
  • Targeted overexpression of G protein-coupled receptor kinase-2 in osteoblasts promotes bone loss. 
  • Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast. 
  • Targets of immunophilin-immunosuppressant complexes are distinct highly conserved regions of calcineurin A. 
  • Template-based docking of a prolactin receptor proline-rich motif octapeptide to FKBP12: implications for cytokine receptor signaling. 
  • Tempting Fate: A Guanylate-Binding Protein Maintains Tomato Fruit Cell Differentiation. 
  • The 120-kDa soluble ectodomain of type XVII collagen is recognized by autoantibodies in patients with pemphigoid and linear IgA dermatosis. 
  • The 25-kilodalton insulin-like growth factor (IGF)-binding protein inhibits both basal and IGF-I-mediated growth of chick embryo pelvic cartilage in vitro. 
  • The BMP antagonist Noggin promotes cranial and spinal neurulation by distinct mechanisms. 
  • The BMP antagonists Chordin and Noggin have essential but redundant roles in mouse mandibular outgrowth. 
  • The C-terminal domain of viral IAP associated factor (cVIAF) is a structural homologue of phosducin: resonance assignments and secondary structure of the C-terminal domain of VIAF. 
  • The Cryptococcus neoformans Flc1 Homologue Controls Calcium Homeostasis and Confers Fungal Pathogenicity in the Infected Hosts. 
  • The DNA damage- and transcription-associated protein paxip1 controls thymocyte development and emigration. 
  • The Drosophila Tis11 protein and its effects on mRNA expression in flies. 
  • The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding. 
  • The FtsZ protofilament and attachment of ZipA--structural constraints on the FtsZ power stroke. 
  • The G185R mutation disrupts function of the iron transporter Nramp2. 
  • The G72/G30 gene complex and cognitive abnormalities in schizophrenia. 
  • The Galpha protein Gpa2 controls yeast differentiation by interacting with kelch repeat proteins that mimic Gbeta subunits. 
  • The MEP2 ammonium permease regulates pseudohyphal differentiation in Saccharomyces cerevisiae. 
  • The Mitochondrial Phosphatase PGAM5 Is Dispensable for Necroptosis but Promotes Inflammasome Activation in Macrophages. 
  • The N-terminal Set-β Protein Isoform Induces Neuronal Death. 
  • The NLRP3 inflammasome detects encephalomyocarditis virus and vesicular stomatitis virus infection. 
  • The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer. 
  • The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA. 
  • The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis. 
  • The Nramp2/DMT1 iron transporter is induced in the duodenum of microcytic anemia mk mice but is not properly targeted to the intestinal brush border. 
  • The RIP1-RIP3 complex initiates mitochondrial fission to fuel NLRP3. 
  • The Trim39 ubiquitin ligase inhibits APC/CCdh1-mediated degradation of the Bax activator MOAP-1. 
  • The U1 RNA-binding site of the U1 small nuclear ribonucleoprotein (snRNP)-associated A protein suggests a similarity with U2 snRNPs. 
  • The acidic domain of the hepatitis C virus NS4A protein is required for viral assembly and envelopment through interactions with the viral E1 glycoprotein. 
  • The actin membrane skeleton in Drosophila development. 
  • The amphiphysin-like protein 1 (ALP1) interacts functionally with the cABL tyrosine kinase and may play a role in cytoskeletal regulation. 
  • The angiotensin II type I receptor-associated protein, ATRAP, is a transmembrane protein and a modulator of angiotensin II signaling. 
  • The auxin influx carrier LAX3 promotes lateral root emergence. 
  • The beta sliding clamp binds to multiple sites within MutL and MutS. 
  • The bone morphogenetic protein antagonist noggin regulates mammalian cardiac morphogenesis. 
  • The cardiac Na+-Ca2+ exchanger binds to the cytoskeletal protein ankyrin. 
  • The cerebral cavernous malformation signaling pathway promotes vascular integrity via Rho GTPases. 
  • The crystal structure of Escherichia coli MoeA and its relationship to the multifunctional protein gephyrin. 
  • The crystal structure of a thermophilic glucose binding protein reveals adaptations that interconvert mono and di-saccharide binding sites. 
  • The disulfide bonding pattern in ficolin multimers. 
  • The effect of an amino acid-lowering diet on the rate of melphalan entry into brain and xenotransplanted glioma. 
  • The gene product Murr1 restricts HIV-1 replication in resting CD4+ lymphocytes. 
  • The glucagon-like peptide-1 receptor agonist Exendin 4 has a protective role in ischemic injury of lean and steatotic liver by inhibiting cell death and stimulating lipolysis. 
  • The glucocorticoid receptor interacting protein 1 (GRIP1) localizes in discrete nuclear foci that associate with ND10 bodies and are enriched in components of the 26S proteasome. 
  • The human gene for mannan-binding lectin-associated serine protease-2 (MASP-2), the effector component of the lectin route of complement activation, is part of a tightly linked gene cluster on chromosome 1p36.2-3. 
  • The immunosuppressant FK506 and its nonimmunosuppressive analog L-685,818 are toxic to Cryptococcus neoformans by inhibition of a common target protein. 
  • The immunosuppressant FK506 inhibits amino acid import in Saccharomyces cerevisiae. 
  • The impact of cystic fibrosis and PSTI/SPINK1 gene mutations on susceptibility to chronic pancreatitis. 
  • The importance of three membrane-distal tyrosines in the adaptor protein NTAL/LAB. 
  • The integrity of a cholesterol-binding pocket in Niemann-Pick C2 protein is necessary to control lysosome cholesterol levels. 
  • The interaction of RGSZ1 with SCG10 attenuates the ability of SCG10 to promote microtubule disassembly. 
  • The interleukin 1 receptor. 
  • The iron transporter DMT1. 
  • The junctional complex of the membrane skeleton. 
  • The mammalian target of rapamycin phosphorylates sites having a (Ser/Thr)-Pro motif and is activated by antibodies to a region near its COOH terminus. 
  • The metabolic regulator ERRα, a downstream target of HER2/IGF-1R, as a therapeutic target in breast cancer. 
  • The mitochondrial citrate/isocitrate carrier plays a regulatory role in glucose-stimulated insulin secretion. 
  • The molecular regulation of iron metabolism. 
  • The mouse retinoid-X receptor-gamma gene: genomic organization and evidence for functional isoforms. 
  • The neuronal actin-binding proteins, neurabin I and neurabin II, recruit specific isoforms of protein phosphatase-1 catalytic subunits. 
  • The organizer factors Chordin and Noggin are required for mouse forebrain development. 
  • The potential repertoire of the innate immune system in the bladder: expression of pattern recognition receptors in the rat bladder and a rat urothelial cell line (MYP3 cells). 
  • The rational design of allosteric interactions in a monomeric protein and its applications to the construction of biosensors. 
  • The response of parathyroid hormone to specific changes in either ionized calcium, ionized magnesium, or protein-bound calcium in humans. 
  • The retinitis pigmentosa GTPase regulator (RPGR) interacts with novel transport-like proteins in the outer segments of rod photoreceptors. 
  • The road to romiplostim approval and beyond. 
  • The role of Grp 78 in alpha 2-macroglobulin-induced signal transduction. Evidence from RNA interference that the low density lipoprotein receptor-related protein is associated with, but not necessary for, GRP 78-mediated signal transduction. 
  • The role of Hipk2-p53 pathways in arsenic-induced autistic behaviors: A translational study from rats to humans. 
  • The role of interferon-β in the treatment of multiple sclerosis and experimental autoimmune encephalomyelitis - in the perspective of inflammasomes. 
  • The role of ion fluxes in hematopoietic cell differentiation. 
  • The role of membrane-associated adaptors in T cell receptor signalling. 
  • The serotonin transporter gene-linked polymorphism and negative emotionality: placing single gene effects in the context of genetic background and environment. 
  • The ubiquilin 1 gene and Alzheimer's disease. 
  • The vesicular glutamate transporter 1 (xVGlut1) is expressed in discrete regions of the developing Xenopus laevis nervous system. 
  • The viral oncoprotein E1A blocks transforming growth factor beta-mediated induction of p21/WAF1/Cip1 and p15/INK4B. 
  • The whole-genome landscape of medulloblastoma subtypes. 
  • The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1. 
  • Therapeutic applications of transcription factor decoy oligonucleotides. 
  • Thiopyranol[2,3,4-c,d]indoles as inhibitors of 5-lipoxygenase, 5-lipoxygenase-activating protein, and leukotriene C4 synthase. 
  • Thioredoxin-interacting protein (Txnip) is a feedback regulator of S-nitrosylation. 
  • Thioredoxin-interacting protein mediates ER stress-induced β cell death through initiation of the inflammasome. 
  • Tissue interactions pattern the mesenchyme of the embryonic mouse lung. 
  • Tocopherol-associated protein suppresses prostate cancer cell growth by inhibition of the phosphoinositide 3-kinase pathway. 
  • Topology of an amiloride-binding protein. 
  • Transcriptional inhibition by carcinogenic chromate: relationship to DNA damage. 
  • Transcriptional regulation of the cholesteryl ester transfer protein gene by the orphan nuclear hormone receptor apolipoprotein AI regulatory protein-1. 
  • Transcriptome-Wide Analysis Identifies Novel Associations With Blood Pressure. 
  • Transfer of radioiodine from iodinated oncornavirus proteins to unlabeled protein carrier during routine procedures for peptide mapping. 
  • Transforming growth factor beta activates the promoter of cyclin-dependent kinase inhibitor p15INK4B through an Sp1 consensus site. 
  • Transforming growth factor-beta-mediated p15(INK4B) induction and growth inhibition in astrocytes is SMAD3-dependent and a pathway prominently altered in human glioma cell lines. 
  • Transgenic indicator mice for studying activated retinoic acid receptors during development. 
  • Transgenic mice expressing a constitutively active retinoic acid receptor in the lens exhibit ocular defects. 
  • Transiently expressed ATG16L1 inhibits autophagosome biogenesis and aberrantly targets RAB11-positive recycling endosomes. 
  • Translating Alzheimer's disease-associated polymorphisms into functional candidates: a survey of IGAP genes and SNPs. 
  • Translation by the adenovirus tripartite leader: elements which determine independence from cap-binding protein complex. 
  • Transmembrane adaptor proteins: organizers of immunoreceptor signalling. 
  • Triiodothyronine (T3) differentially affects T3-receptor/retinoic acid receptor and T3-receptor/retinoid X receptor heterodimer binding to DNA. 
  • Trypsin digestion increases Na(+)-H+ exchange rates in native rabbit brush border membrane. 
  • Tubulin and calmodulin. Effects of microtubule and microfilament inhibitors on localization in the mitotic apparatus. 
  • Two kinetically-distinct components of UDP-glucuronic acid transport in rat liver endoplasmic reticulum. 
  • Two mechanistically distinct immune evasion proteins of cowpox virus combine to avoid antiviral CD8 T cells. 
  • Two oligomeric forms of plasma ficolin have differential lectin activity. 
  • Ubiquitin fold modifier 1 (UFM1) and its target UFBP1 protect pancreatic beta cells from ER stress-induced apoptosis. 
  • Ubiquitylated Tax targets and binds the IKK signalosome at the centrosome. 
  • Ubiquitylation of p53 by the APC/C inhibitor Trim39. 
  • Uncoupling PR-gene expression from NPR1 and bacterial resistance: Characterization of the dominant Arabidopsis cpr6 mutant. 
  • Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia. 
  • Unmasking the osteoinductive effects of a G-protein-coupled receptor (GPCR) kinase (GRK) inhibitor by treatment with PTH(1-34). 
  • Upregulation of VEGF-C by androgen depletion: the involvement of IGF-IR-FOXO pathway. 
  • Upregulation of mTORC2 activation by the selective agonist of EPAC, 8-CPT-2Me-cAMP, in prostate cancer cells: assembly of a multiprotein signaling complex. 
  • Upstream regulatory role for XIAP in receptor-mediated apoptosis. 
  • Uric acid is a danger signal of increasing risk for osteoarthritis through inflammasome activation. 
  • VIAF, a conserved inhibitor of apoptosis (IAP)-interacting factor that modulates caspase activation. 
  • Vesicular zinc promotes presynaptic and inhibits postsynaptic long-term potentiation of mossy fiber-CA3 synapse. 
  • Viral Replication Complexes Are Targeted by LC3-Guided Interferon-Inducible GTPases. 
  • Virus binding to a plasma membrane receptor triggers interleukin-1 alpha-mediated proinflammatory macrophage response in vivo. 
  • XIAP Is a copper binding protein deregulated in Wilson's disease and other copper toxicosis disorders. 
  • XIAP inhibition of caspase-3 preserves its association with the Apaf-1 apoptosome and prevents CD95- and Bax-induced apoptosis. 
  • XIAP: cell death regulation meets copper homeostasis. 
  • ZCCHC8, the nuclear exosome targeting component, is mutated in familial pulmonary fibrosis and is required for telomerase RNA maturation. 
  • ZipA and FtsA* stabilize FtsZ-GDP miniring structures. 
  • [NLRP3 inflammasome and multiple sclerosis/EAE]. 
  • [Protein transduction domain peptide mediates delivery to the brain via the blood-brain barrier in Drosophila]. 
  • beta-Adrenergic activation of p38 MAP kinase in adipocytes: cAMP induction of the uncoupling protein 1 (UCP1) gene requires p38 MAP kinase. 
  • beta-cell function in normal rats made chronically hyperleptinemic by adenovirus-leptin gene therapy. 
  • cAMP-associated inhibition of Na+-H+ exchanger in rabbit kidney brush-border membranes. 
  • mRNA translation is compartmentalized to the endoplasmic reticulum following physiological inhibition of cap-dependent translation. 
  • mTORC2 in Thymic Epithelial Cells Controls Thymopoiesis and T Cell Development. 
  • miR-17-92 cluster targets phosphatase and tensin homology and Ikaros Family Zinc Finger 4 to promote TH17-mediated inflammation. 
  • p38 mitogen-activated protein kinase is the central regulator of cyclic AMP-dependent transcription of the brown fat uncoupling protein 1 gene. 
• 

  Keywords of People

  • Bennett, Vann, George Barth Geller Distinguished Professor of Molecular Biology, Duke Cancer Institute
  • Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Erickson, Harold Paul, James B. Duke Distinguished Professor Emeritus, Cell Biology
  • Ferreira, Paulo Alexandre, Associate Professor in Ophthalmology, Pathology
  • Hogan, Brigid L. M., Research Professor of Cell Biology, Cell Biology
  • Krangel, Michael S., George Barth Geller Distinguished Professor of Immunology, Integrative Immunobiology
  • Middleton, John Paul, Professor of Medicine, Medicine, Nephrology
  • Milano, Carmelo Alessio, Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery, Surgery, Cardiovascular and Thoracic Surgery
  • Muir, Kelly Walton, Associate Professor of Ophthalmology, Ophthalmology, Glaucoma
  • Sullivan, Daniel Carl, Professor Emeritus of Radiology, Radiology