Cartilage

• 

  Subject Areas on Research

  • 1,25-Dihydroxyvitamin D3 stimulates avian and mammalian cartilage growth in vitro. 
  • A bioresponsive hydrogel tuned to chondrogenesis of human mesenchymal stem cells. 
  • A comparative analysis of marine mammal tracheas. 
  • A paper by Jones et al. Alterations in the Young's modulus and volumetric properties of chondrocytes isolated from normal and osteoarthritic human cartilage (Journal of Biomechanics 32, 1999, 119-127). 
  • A posterior 3-portal arthroscopic approach for isolated subtalar arthrodesis. 
  • A role for a lithium-inhibited Golgi nucleotidase in skeletal development and sulfation. 
  • Absence of posttraumatic arthritis following intraarticular fracture in the MRL/MpJ mouse. 
  • Accuracy and precision of quantitative assessment of cartilage morphology by magnetic resonance imaging at 3.0T. 
  • Adenosine 3',5'-monophosphate: a modulator of embryonic chick cartilage growth. 
  • Anterior chest wall: frequency of anatomic variations in children. 
  • Application of a unique monoclonal antibody as a marker for nonproliferating subpopulations of cells of some tissue. 
  • Ascorbic acid accumulates in cartilage in vivo. 
  • Ascorbic acid increases the severity of spontaneous knee osteoarthritis in a guinea pig model. 
  • Auto-segmentation of the tibia and femur from knee MR images via deep learning and its application to cartilage strain and recovery. 
  • Axin2 regulates chondrocyte maturation and axial skeletal development. 
  • Beware of open triradiate cartilage: 1 in 4 patients will lose > 10° of correction following posterior only fusion. 
  • CRISPR/Cas9 Editing of Murine Induced Pluripotent Stem Cells for Engineering Inflammation-Resistant Tissues. 
  • Calcitonin stimulates growth and maturation of embryonic chick pelvic cartilage in vitro. 
  • Cartilage as an interposition material to prevent transphyseal bone bridge formation: an experimental model. 
  • Cartilage tissue engineering: Directed differentiation of embryonic stem cells in three-dimensional hydrogel culture. 
  • Cartilage tumours and bone development: molecular pathology and possible therapeutic targets. 
  • Cartilage-binding antibodies induce pain through immune complex-mediated activation of neurons. 
  • Cartilage-specific RBPjκ-dependent and -independent Notch signals regulate cartilage and bone development. 
  • Cartilage-specific β-catenin signaling regulates chondrocyte maturation, generation of ossification centers, and perichondrial bone formation during skeletal development. 
  • Cartilaginous variant of congenital adenomatoid malformation of the lung. 
  • Cellular patterns of insulin-like growth factor system gene expression in murine chondrogenesis and osteogenesis. 
  • Characterization of Cartilage Injury and Associated Treatment at the Time of Primary Anterior Cruciate Ligament Reconstruction. 
  • Characterization of a genetically engineered elastin-like polypeptide for cartilaginous tissue repair. 
  • Chondrocyte transport and concentration of ascorbic acid is mediated by SVCT2. 
  • Chondrogenic differentiation of adipose-derived adult stem cells in agarose, alginate, and gelatin scaffolds. 
  • Chondrogenic potential of adipose tissue-derived stromal cells in vitro and in vivo. 
  • Colocalization of BMP 7 and BMP 2 RNAs suggests that these factors cooperatively mediate tissue interactions during murine development. 
  • Comparative studies of prosthetic materials in the left atrium of the dog. 
  • Comparison of prosthetic graft materials as intracardiac right atrial patches. 
  • Comparison of the chondrogenic potential of free and vascularized perichondrium in the airway. 
  • Conditioned medium differentially regulates matrix protein gene expression in cells of the intervertebral disc. 
  • Demineralized Murine Skeletal Histology. 
  • Derivation of chondrogenically-committed cells from human embryonic cells for cartilage tissue regeneration. 
  • Diet-induced obesity differentially regulates behavioral, biomechanical, and molecular risk factors for osteoarthritis in mice. 
  • Distinct Roles of Glutamine Metabolism in Benign and Malignant Cartilage Tumors With IDH Mutations. 
  • Distribution of immunoreactive androgen-binding protein/sex hormone-binding globulin in tissues of the fetal rat. 
  • Effect of basic fibroblast growth factor on angiogenesis and growth of isografted bone: quantitative in vitro-in vivo analysis in mice. 
  • Effect of graft height mismatch on contact pressures with osteochondral grafting of the talus. 
  • Effect of intraoperative ischemia on chondrogenesis by vascularized auricular perichondrium grafted in the airway. 
  • Effect of walking on in vivo tibiofemoral cartilage strain in ACL-deficient versus intact knees. 
  • Electrospun cartilage-derived matrix scaffolds for cartilage tissue engineering. 
  • Embryonic chick cartilage produces its own somatomedin-like peptide to stimulate cartilage growth in vitro. 
  • Endogenous CCN family member WISP1 inhibits trauma-induced heterotopic ossification. 
  • Engineering superficial zone features in tissue engineered cartilage. 
  • Enhanced chondrogenic differentiation of embryonic stem cells by coculture with hepatic cells. 
  • Extended applications of vascularized preauricular and helical rim flaps in reconstruction of nasal defects. 
  • First qualification study of serum biomarkers as indicators of total body burden of osteoarthritis. 
  • Genome Engineering of Stem Cells for Autonomously Regulated, Closed-Loop Delivery of Biologic Drugs. 
  • HES factors regulate specific aspects of chondrogenesis and chondrocyte hypertrophy during cartilage development. 
  • Helix-loop-helix transcription factors E12 and E47 are not essential for skeletal or cardiac myogenesis, erythropoiesis, chondrogenesis, or neurogenesis. 
  • High-Strength Hydrogel Attachment through Nanofibrous Reinforcement. 
  • Homologous and heterologous growth hormones fail to stimulate avian cartilage growth in vitro. 
  • Hormonal activation of ornithine decarboxylase in embryonic chick pelvic cartilage. 
  • Hormonal stimulation of avian embryonic cartilage growth in vitro: histologic and ultrastructural features. 
  • Ihh controls cartilage development by antagonizing Gli3, but requires additional effectors to regulate osteoblast and vascular development. 
  • In situ friction measurement on murine cartilage by atomic force microscopy. 
  • In vitro stimulation of alkaline phosphatase activity in immature embryonic chick pelvic cartilage by adenosine 3'5'-monophosphate. 
  • In vivo cartilage contact strains in patients with lateral ankle instability. 
  • In vivo commitment and functional tissue regeneration using human embryonic stem cell-derived mesenchymal cells. 
  • In vivo tibiofemoral contact analysis using 3D MRI-based knee models. 
  • Interconnected macroporous poly(ethylene glycol) cryogels as a cell scaffold for cartilage tissue engineering. 
  • Intra-Articular Synovial Fluid With Hematoma After Ankle Fracture Promotes Cartilage Damage In Vitro Partially Attenuated by Anti-Inflammatory Agents. 
  • Invited Discussion on: Septorhinoplasty and Septoplasty-Outcomes of a Large Cohort Using Autologous Versus Homologous Cartilage 1999-2019. 
  • Isolation and Culture of Murine Primary Chondrocytes: Costal and Growth Plate Cartilage. 
  • Knockdown of the cell cycle inhibitor p21 enhances cartilage formation by induced pluripotent stem cells. 
  • Lack of requirement of osteopontin for inflammation, bone erosion, and cartilage damage in the K/BxN model of autoantibody-mediated arthritis. 
  • Magnetic Resonance Imaging Characterization and Clinical Outcomes After NeoCart Surgical Therapy as a Primary Reparative Treatment for Knee Cartilage Injuries. 
  • Mechanical stress and nitric oxide influence leukotriene production in cartilage. 
  • Metacarpal reconstruction with free autogenous cartilage and bone following tumor resection. A case report. 
  • Molecular diffusion in tissue-engineered cartilage constructs: effects of scaffold material, time, and culture conditions. 
  • Morphogenetic signals from chondrocytes promote chondrogenic and osteogenic differentiation of mesenchymal stem cells. 
  • Multiple roles for Sox2 in the developing and adult mouse trachea. 
  • Mutations in Fibronectin Cause a Subtype of Spondylometaphyseal Dysplasia with "Corner Fractures". 
  • Mutations in fam20b and xylt1 reveal that cartilage matrix controls timing of endochondral ossification by inhibiting chondrocyte maturation. 
  • NGF-TrkA signaling dictates neural ingrowth and aberrant osteochondral differentiation after soft tissue trauma. 
  • Neural network analysis identifies scaffold properties necessary for in vitro chondrogenesis in elastin-like polypeptide biopolymer scaffolds. 
  • Nonoperative and Operative Soft-Tissue and Cartilage Regeneration and Orthopaedic Biologics of the Foot and Ankle: An Orthoregeneration Network Foundation Review. 
  • Novel Genetic Variants for Cartilage Thickness and Hip Osteoarthritis. 
  • Oligo(trimethylene carbonate)-poly(ethylene glycol)-oligo(trimethylene carbonate) triblock-based hydrogels for cartilage tissue engineering. 
  • Ontogenesis of prolactin receptors in the human fetus in early gestation. Implications for tissue differentiation and development. 
  • Optimizing Arthroscopy for Osteochondral Lesions of the Talus: The Effect of Ankle Positions and Distraction During Anterior and Posterior Arthroscopy in a Cadaveric Model. 
  • Osteochondral allograft of the talus. 
  • Osteochondral talar allograft for large osteochondral defects: technique tip. 
  • PTHrP targets HDAC4 and HDAC5 to repress chondrocyte hypertrophy. 
  • Palmitoyl acyltransferase, Zdhhc13, facilitates bone mass acquisition by regulating postnatal epiphyseal development and endochondral ossification: a mouse model. 
  • Parathyroid hormone stimulates growth of embryonic chick pelvic cartilage in vitro. 
  • Parathyroid hormone-related protein regulates glioma-associated oncogene transcriptional activation: lessons learned from bone development and cartilage neoplasia. 
  • Phosphotyrosine and phosphoprotein phosphatase activity of alkaline phosphatase in mineralizing cartilage. 
  • Preparation techniques for the injection of human autologous cartilage: an ex vivo feasibility study. 
  • Presurgical columellar elongation and primary retrograde nasal reconstruction in one-stage bilateral cleft lip and nose repair. 
  • Protein modification by deamidation indicates variations in joint extracellular matrix turnover. 
  • Reconstruction of longitudinal stability of the forearm after disruption of interosseous ligament and radial head excision (Essex-Lopresti lesion). 
  • Reconstruction of nasal defects 1.5 cm or smaller. 
  • Regulation of chondrocytic gene expression by biomechanical signals. 
  • Relapsing polychondritis. 
  • Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells. 
  • Results with titanium ossicular reconstruction prostheses. 
  • Retinoic acid receptor alpha function in vertebrate limb skeletogenesis: a modulator of chondrogenesis. 
  • RoBo-1, a novel member of the urokinase plasminogen activator receptor/CD59/Ly-6/snake toxin family selectively expressed in rat bone and growth plate cartilage. 
  • Role of Fresh Osteochondral Allografts for Large Talar Osteochondral Lesions. 
  • Role of Fresh Osteochondral Allografts for Large Talar Osteochondral Lesions. 
  • Selective Enzymatic Digestion of Proteoglycans and Collagens Alters Cartilage T1rho and T2 Relaxation Times. 
  • Sonic hedgehog from pharyngeal arch 1 epithelium is necessary for early mandibular arch cell survival and later cartilage condensation differentiation. 
  • Specific nuclear binding of adenosine 3',5'-monophosphate-binding protein complex with subsequent poly(A) RNA synthesis in embryonic chick cartilage. 
  • Spine Patterning Is Guided by Segmentation of the Notochord Sheath. 
  • Stimulation of cartilage amino acid uptake by growth hormone-dependent factors in serum. Mediation by adenosine 3':5'-monophosphate. 
  • Stimulation of cartilage macromolecule synthesis by adenosine 3',5'-monophosphate. 
  • Subsequent Surgery After Revision Anterior Cruciate Ligament Reconstruction: Rates and Risk Factors From a Multicenter Cohort. 
  • Synthesis and in vitro evaluation of enzymatically cross-linked elastin-like polypeptide gels for cartilaginous tissue repair. 
  • TAK1 regulates cartilage and joint development via the MAPK and BMP signaling pathways. 
  • TCDD disrupts hypural skeletogenesis during medaka embryonic development. 
  • TRPV4 as a therapeutic target for joint diseases. 
  • Targets to tackle--the pathophysiology of the disease. 
  • Temperature alterations of infrared light absorption by cartilage and cornea under free-electron laser radiation. 
  • The 25-kilodalton insulin-like growth factor (IGF)-binding protein inhibits both basal and IGF-I-mediated growth of chick embryo pelvic cartilage in vitro. 
  • The cartilage thickness distribution in the tibiofemoral joint and its correlation with cartilage-to-cartilage contact. 
  • The effect of mesenchymal stem cell sheets on structural allograft healing of critical sized femoral defects in mice. 
  • The effects of adipokines on cartilage and meniscus catabolism. 
  • The effects of femoral graft placement on cartilage thickness after anterior cruciate ligament reconstruction. 
  • The feelgood mutation in zebrafish dysregulates COPII-dependent secretion of select extracellular matrix proteins in skeletal morphogenesis. 
  • The forkhead/winged helix gene Mf1 is disrupted in the pleiotropic mouse mutation congenital hydrocephalus. 
  • The use of autologous adult, allogenic juvenile, and combined juvenile-adult cartilage fragments for the repair of chondral defects. 
  • Time-resolved, light scattering measurements of cartilage and cornea denaturation due to free electron laser radiation. 
  • Tissue-engineered cartilage with inducible and tunable immunomodulatory properties. 
  • Transient receptor potential vanilloid 4 as a regulator of induced pluripotent stem cell chondrogenesis. 
  • Trends in Knee Articular Cartilage Treatments: An American Board of Orthopaedic Surgery Database Study. 
  • Triiodothyronine stimulates maturation of porcine growth-plate cartilage in vitro. 
  • Triiodothyronine stimulation of in vitro growth and maturation of embryonic chick cartilage. 
  • Type II collagen markers in osteoarthritis: what do they indicate? 
  • Unipolar Osteochondral Allograft Transplantation of the Ankle for Posttraumatic Tibial Necrosis: A Case Report. 
  • Urea as a passive transport marker for arthritis biomarker studies. 
  • Vascularized auricular perichondrium in airway reconstruction: the effects of stenting with and without a mucosal graft. 
  • Will we be able to repair osteoarthritic joints? New drugs and surgical techniques for cartilage problems. 
  • [Diagnosis and treatment of osteochondral lesions of the talus]. 
• 

  Keywords of People

  • Charles, Hal Cecil, Adjunct Associate Professor in the Department of Radiology, Radiology
  • Cohen, Seth Morris, Professor of Head and Neck Surgery & Communication Sciences, Head and Neck Surgery & Communication Sciences
  • Esclamado, Ramon Mitra, Richard Hall Chaney, Sr. Distinguished Professor Emeritus of Otolaryngology, Head and Neck Surgery & Communication Sciences
  • Freemark, Michael Scott, Robert C. Atkins, M.D. and Veronica Atkins Distinguished Professor of Pediatrics, in the School of Medicine, Pediatrics, Endocrinology
  • Hilton, Matthew James, Associate Professor in Orthopaedic Surgery, Cell Biology
  • Olson, Steven Arthur, Goldner Jones Distinguished Professor of Orthopaedic Surgery, Orthopaedic Surgery
  • Wittstein, Jocelyn Ross, Associate Professor of Orthopaedic Surgery, Orthopaedic Surgery