Catalase

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  Subject Areas on Research

  • A comprehensive evaluation of catalase-like activity of different classes of redox-active therapeutics. 
  • A determination of the outer dimensions of oncornaviruses by several electron microscopic procedures. 
  • Adaptation to hyperoxia in the neonatal rat: kinetic parameters of the oxygen-mediated induction of lung superoxide dismutases, catalase and glutathione peroxidase. 
  • Alterations in cellular enzymes and tissue metabolism in the oxygen toxic primate lung. 
  • An age-related difference in hyperoxia lethality: role of lung antioxidant defense mechanisms. 
  • AnkB, a periplasmic ankyrin-like protein in Pseudomonas aeruginosa, is required for optimal catalase B (KatB) activity and resistance to hydrogen peroxide. 
  • Antioxidant defense mechanisms in cultured pleural mesothelial cells. 
  • Antioxidant enzyme activities and malondialdehyde, glutathione and methemoglobin concentrations in channel catfish exposed to DEF and n-butyl mercaptan. 
  • Antioxidative defense enzymes in placenta protect placenta and fetus in inherited thrombophilia from hydrogen peroxide. 
  • Avicinylation (thioesterification): a protein modification that can regulate the response to oxidative and nitrosative stress. 
  • Changes in superoxide dismutase and catalase activities of rat brain regions during early global transient ischemia/reperfusion. 
  • Chronic ethanol treatment induces H2O2 production selectively in pericentral regions of the liver lobule. 
  • Correlation between membrane potential changes and superoxide production in human granulocytes stimulated by phorbol myristate acetate. Evidence for defective activation in chronic granulomatous disease. 
  • Effects of 2,4-dichlorophenoxyacetic acid and picloram on biotransformation, peroxisomal and serum enzyme activities in channel catfish (Ictalurus punctatus). 
  • Electron acceptor function of O2 in radical N-demethylation reactions catalyzed by hemeproteins. 
  • Enzyme dehydration using Microglassification™ preserves the protein's structure and function. 
  • Experimental effects of hyperbaric oxgen on selected clostridial species. I. In-vitro studies. 
  • Facilitated light microscopic cytochemical diagnosis of acute myelogenous leukemia. 
  • Flavin-dependent antioxidant properties of a new series of meso-N,N'-dialkyl-imidazolium substituted manganese(III) porphyrins. 
  • Genome-wide analysis of genomic alterations induced by oxidative DNA damage in yeast. 
  • Hemoglobin-induced endothelial cell permeability is controlled, in part, via a myeloid differentiation primary response gene-88-dependent signaling mechanism. 
  • High glucose stimulates angiotensinogen gene expression via reactive oxygen species generation in rat kidney proximal tubular cells. 
  • Human erythrocyte catalase: an improved method of isolation and a reevaluation of reported properties. 
  • Hydrogen peroxide production by alveolar type II cells, alveolar macrophages, and endothelial cells. 
  • Hydrogen peroxide production by monoamine oxidase during ischemia-reperfusion in the rat brain. 
  • Hydrogen peroxide promotes aging-related platelet hyperactivation and thrombosis. 
  • Induction of oxidative cell damage by photo-treatment with zinc meta N-methylpyridylporphyrin. 
  • Involvement of reactive oxygen species in the electrochemical inhibition of barnacle (Amphibalanus amphitrite) settlement. 
  • Klotho, an antiaging molecule, attenuates oxidant-induced alveolar epithelial cell mtDNA damage and apoptosis. 
  • L-arginine enhances injury in the isolated rabbit lung during hyperoxia. 
  • LKB1 reduces ROS-mediated cell damage via activation of p38. 
  • Measuring the resolution of uncompressed plastic sections cut using an oscillating knife ultramicrotome. 
  • Mitochondrial adaptations to obesity-related oxidant stress. 
  • Muscle oxidative capacity during IL-6-dependent cancer cachexia. 
  • Neuroprotective effect of curcumin in an experimental rat model of subarachnoid hemorrhage. 
  • Nitrofurantoin-stimulated superoxide production by channel catfish (Ictalurus punctatus) hepatic microsomal and soluble fractions. 
  • Nitrosative stress: activation of the transcription factor OxyR. 
  • Overexpression of human catalase inhibits proliferation and promotes apoptosis in vascular smooth muscle cells. 
  • Oxidant, mixed-function oxidase and peroxisomal responses in channel catfish exposed to a bleached kraft mill effluent. 
  • Oxidants, antioxidants and the ischemic brain. 
  • Oxidative and excitatory mechanisms of developmental neurotoxicity: transcriptional profiles for chlorpyrifos, diazinon, dieldrin, and divalent nickel in PC12 cells. 
  • PO2-dependent hydroxyl radical production during ischemia-reperfusion lung injury. 
  • Peroxide detoxification affecting the production of immunoglobulin by mouse myeloma tumor cells in vitro. 
  • Peroxynitrite formation and decreased catalase activity in autoimmune MRL-lpr/lpr mice. 
  • Prevention of H2O2 generation by monoamine oxidase protects against CNS O2 toxicity. 
  • Regional H2O2 concentration in rat brain after hyperoxic convulsions. 
  • Reversible pulmonary oxygen toxicity in the primate. 
  • Role of antioxidant enzymes in the induction of increased experimental metastasis by hydroxyurea. 
  • Studies of phagocytosis in chronic granulomatous disease. 
  • Superoxide dismutase and catalase of calf trabecular meshwork. 
  • Superoxide dismutase potentiates platelet-activating factor-induced injury in perfused lung. 
  • Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor. 
  • The Cryptococcus neoformans catalase gene family and its role in antioxidant defense. 
  • The complete amino acid sequence of bovine liver catalase and the partial sequence of bovine erythrocyte catalase. 
  • The partial amino acid sequence of human erythrocyte catalase. 
  • The role of superoxide anion generation in phagocytic bactericidal activity. Studies with normal and chronic granulomatous disease leukocytes. 
  • The use of diaminobenzidine for spectrophotometric and acrylamide gel detection of sulfite oxidase and its applicability to hydrogen peroxide-generating enzymes. 
  • Tyloxapol confers durable protection against hyperoxic lung injury in the rat. 
  • Ultrastructural alterations in liver of medaka (Oryzias latipes) exposed to diethylnitrosamine. 
  • Vanadium-induced STAT-1 activation in lung myofibroblasts requires H2O2 and P38 MAP kinase. 
  • c-myc-Dependent hepatoma cell apoptosis results from oxidative stress and not a deficiency of growth factors. 
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  Keywords of People

  • Hirschey, Matthew, Associate Professor, Pharmacology & Cancer Biology
  • Warner, David Samuel, Distinguished Distinguished Professor of Anesthesiology, in the School of Medicine, Neurobiology