Cations

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  Subject Areas on Research

  • A calcium-activated, nonselective cationic conductance in Aplysia silent neurons. 
  • A serum-resistant cytofectin for cellular delivery of antisense oligodeoxynucleotides and plasmid DNA. 
  • A single acidic residue can guide binding site selection but does not govern QacR cationic-drug affinity. 
  • A spontaneous, recurrent mutation in divalent metal transporter-1 exposes a calcium entry pathway. 
  • Activation by odorants of a multistate cation channel from olfactory cilia. 
  • Additivity and the physical basis of multivalency effects: a thermodynamic investigation of the calcium EDTA interaction. 
  • Adjunctive β2-agonist treatment reduces glycogen independently of receptor-mediated acid α-glucosidase uptake in the limb muscles of mice with Pompe disease. 
  • Administration of atrial natriuretic factor inhibits sodium-coupled transport in proximal tubules. 
  • Agonist-specific effects of monovalent and divalent cations on adenylate cyclase-coupled alpha adrenergic receptors in rabbit platelets. 
  • Amphiphilic cationic Zn-porphyrins with high photodynamic antimicrobial activity. 
  • An anionic impurity in preparations of cytochrome c interferes with assays of cationic catalysts of the dismutation of the superoxide anion radical. 
  • An anionic, endosome-escaping polymer to potentiate intracellular delivery of cationic peptides, biomacromolecules, and nanoparticles. 
  • Aquaporins and ion conductance. 
  • Assembly of alternating polycation and DNA multilayer films by electrostatic layer-by-layer adsorption. 
  • Atmospheric CO2 enrichment facilitates cation release from soil. 
  • Atom Transfer Radical Polymerization of Multishelled Cationic Corona for the Systemic Delivery of siRNA. 
  • Boranophosphates support the RNase H cleavage of polyribonucleotides. 
  • Calcium-dependent and calcium-independent adhesive mechanisms are present during initial binding events of neural retina cells. 
  • Cation-Activated Avidity for Rapid Reconfiguration of DNA Nanodevices. 
  • Cation-Inhibited Transport of Graphene Oxide Nanomaterials in Saturated Porous Media: The Hofmeister Effects. 
  • Cationic amphiphilic Zn-porphyrin with high antifungal photodynamic potency. 
  • Cationic nanoparticle as an inhibitor of cell-free DNA-induced inflammation. 
  • Characterization of the energy-dependent, mating factor-activated Ca2+ influx in Saccharomyces cerevisiae. 
  • Characterization of the monovalent and divalent cation requirements for the xenobiotic carboxylic acid: CoA ligases of bovine liver mitochondria. 
  • Charge splitters and charge transport junctions based on guanine quadruplexes. 
  • Conformational transition of DNA induced by cationic lipid vesicle in acidic solution: spectroscopy investigation. 
  • Construction and control of plasmid DNA network. 
  • Crucial role of copper in detection of metal-coordinating odorants. 
  • Crystal structures of QacR-diamidine complexes reveal additional multidrug-binding modes and a novel mechanism of drug charge neutralization. 
  • DNA repair protein O6-alkylguanine-DNA alkyltransferase is phosphorylated by two distinct and novel protein kinases in human brain tumour cells. 
  • Differential coordination demands in Fe versus Mn water-soluble cationic metalloporphyrins translate into remarkably different aqueous redox chemistry and biology. 
  • Differential regulation of receptor-stimulated cyclic adenosine monophosphate production by polyvalent cations in MC3T3-E1 osteoblasts. 
  • Distinct MutS DNA-binding modes that are differentially modulated by ATP binding and hydrolysis. 
  • Drosophila Subdued is a moonlighting transmembrane protein 16 (TMEM16) that transports ions and phospholipids. 
  • Dynamic regulation of copper uptake and detoxification genes in Saccharomyces cerevisiae. 
  • Effect of polymer chain length on membrane perturbation activity of cationic phenylene ethynylene oligomers and polymers. 
  • Effect of side-chain structures on gene transfer efficiency of biodegradable cationic polyphosphoesters. 
  • Effects of perchlorate on the molecules of excitation-contraction coupling of skeletal and cardiac muscle. 
  • Efficient gene transfer with adeno-associated virus-based plasmids complexed to cationic liposomes for gene therapy of human prostate cancer. 
  • Evidence for heteromorphic chromatin fibers from analysis of nucleosome interactions. 
  • Fluorescence detection of cationic amyloid fibrils in human semen. 
  • Formulations which increase the size of lipoplexes prevent serum-associated inhibition of transfection. 
  • Forskolin stimulation of water and cation permeability in aquaporin 1 water channels. 
  • FtsZ condensates: an in vitro electron microscopy study. 
  • Functional lipids and lipoplexes for improved gene delivery. 
  • Gold(I)-catalyzed dynamic kinetic enantioselective intramolecular hydroamination of allenes. 
  • Growth hormone and prolactin binding to rabbit liver plasma membranes. 
  • Growth of cationic lipid toward bilayer lipid membrane by solution spreading: scanning probe microscopy study. 
  • Heteromeric assembly of acid-sensitive ion channel and epithelial sodium channel subunits. 
  • How cations change peptide structure. 
  • Idealization and simulation of single ion channel data. 
  • Improved efficacy of stem cell labeling for magnetic resonance imaging studies by the use of cationic liposomes. 
  • Improved non-chromatographic purification of a recombinant protein by cationic elastin-like polypeptides. 
  • Incorporation of active DNA/cationic polymer polyplexes into hydrogel scaffolds. 
  • Increased vascular smooth muscle contractility in TRPC6-/- mice. 
  • Integrated single-walled carbon nanotube/microfluidic devices for the study of the sensing mechanism of nanotube sensors. 
  • Investigation of the influence on conformational transition of DNA induced by cationic lipid vesicles. 
  • Ionophore 4-BrA23187 transports Zn2+ and Mn2+ with high selectivity over Ca2+. 
  • Kinetics of release of serotonin from isolated secretory granules. II. Ion exchange determines the diffusivity of serotonin. 
  • Lic4, a nuclear phosphoprotein that cooperates with calcineurin to regulate cation homeostasis in Saccharomyces cerevisiae. 
  • Mediator-free amperometric determination of toxic substances based on their inhibition of immobilized horseradish peroxidase. 
  • Membrane perturbation activity of cationic phenylene ethynylene oligomers and polymers: selectivity against model bacterial and mammalian membranes. 
  • Nanoscale neuro-integrative coatings for neural implants. 
  • Native recombinant cyclophilins A, B, and C degrade DNA independently of peptidylprolyl cis-trans-isomerase activity. Potential roles of cyclophilins in apoptosis. 
  • Novel amphiphilic cationic porphyrin and its Ag(II) complex as potential anticancer agents. 
  • Nucleic acid-binding polymers as anti-inflammatory agents. 
  • O-Alkyl dioleoylphosphatidylcholinium compounds: the effect of varying alkyl chain length on their physical properties and in vitro DNA transfection activity. 
  • Optical detection of polycations via polymer film-modified microtiter plates: response mechanism and bioanalytical applications. 
  • Polyphosphoramidate gene carriers: effect of charge group on gene transfer efficiency. 
  • Potent immune responses in rhesus macaques induced by nonviral delivery of a self-amplifying RNA vaccine expressing HIV type 1 envelope with a cationic nanoemulsion. 
  • QacR-cation recognition is mediated by a redundancy of residues capable of charge neutralization. 
  • Radioiodination via D-amino acid peptide enhances cellular retention and tumor xenograft targeting of an internalizing anti-epidermal growth factor receptor variant III monoclonal antibody. 
  • Rational design of superoxide dismutase (SOD) mimics: the evaluation of the therapeutic potential of new cationic Mn porphyrins with linear and cyclic substituents. 
  • Recognition of multiple drugs by a single protein: a trivial solution of an old paradox. 
  • Regulation of cation channels in liver cells by intracellular calcium and protein kinase C. 
  • Regulation of thromboxane receptor (TP) phosphorylation by protein phosphatase 1 (PP1) and PP2A. 
  • Revision of standards for adjusting the cation content of Mueller-Hinton broth for testing susceptibility of Pseudomonas aeruginosa to aminoglycosides. 
  • Soil acidity reconstruction based on tree ring information of a dominant species Abies fabri in the subalpine forest ecosystems in southwest China. 
  • Stimulation and inhibition of 1,3-bis(2-chloroethyl)-1-nitrosourea-induced strand breaks and interstrand cross-linking in Col E1 plasmid deoxyribonucleic acid by polyamines and inorganic cations. 
  • Substrate-mediated DNA delivery: role of the cationic polymer structure and extent of modification. 
  • Suprastructures and dynamic properties of Mycobacterium tuberculosis FtsZ. 
  • Surface-tethered DNA complexes for enhanced gene delivery. 
  • The Aspergillus fumigatus P-type Golgi apparatus Ca2+/Mn2+ ATPase PmrA is involved in cation homeostasis and cell wall integrity but is not essential for pathogenesis. 
  • The structure of a CREB bZIP.somatostatin CRE complex reveals the basis for selective dimerization and divalent cation-enhanced DNA binding. 
  • Thermodynamics of reactions catalyzed by anthranilate synthase. 
  • Time and distance dependence of reversible polymer bridging followed by single-molecule force spectroscopy. 
  • Toxicity of cationic lipid-ribozyme complexes in human prostate tumor cells can mimic ribozyme activity. 
  • Transport properties of the calcium ionophore ETH-129. 
  • Two affinity states of N-methyl-D-aspartate recognition sites: modulation by cations. 
  • Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor. 
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  Keywords of People

  • Erickson, Harold Paul, James B. Duke Distinguished Professor of Cell Biology, Biomedical Engineering
  • Juvvadi, Praveen Rao, Associate Professor in Pediatrics, Pediatrics, Infectious Diseases