Cell Division

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  Subject Areas on Research

  • 1,10-Phenanthroline reversibility inhibits proliferation of two human prostate carcinoma cell lines (PC-3 and DU145). 
  • 1,25-Dihydroxyvitamin D3 stimulates avian and mammalian cartilage growth in vitro. 
  • A 57,000-mol-wt protein uniquely present in nonproliferating cells and senescent human fibroblasts. 
  • A CD91-positive subset of CD11c+ blood dendritic cells: characterization of the APC that functions to enhance adaptive immune responses against CD91-targeted antigens. 
  • A Protocol for the Production of Integrase-deficient Lentiviral Vectors for CRISPR/Cas9-mediated Gene Knockout in Dividing Cells. 
  • A Unified Model for Treadmilling and Nucleation of Single-Stranded FtsZ Protofilaments. 
  • A biochemical genetic study of the role of specific nucleoside kinases in deoxyadenosine phosphorylation by cultured human cells. 
  • A broad competence to respond to SHORT ROOT revealed by tissue-specific ectopic expression. 
  • A collection of cortical crescents: asymmetric protein localization in CNS precursor cells. 
  • A comparison of murine T-cell-depleted adult bone marrow and full-term fetal blood cells in hematopoietic engraftment and immune reconstitution. 
  • A deadly game of musical chairs: survival of cells transplanted for myocardial repair. 
  • A double-blind randomized study on the effects of red clover isoflavones on the endometrium. 
  • A gene therapy strategy using a transcription factor decoy of the E2F binding site inhibits smooth muscle proliferation in vivo. 
  • A genomic view of eukaryotic DNA replication. 
  • A glial fibrillary acidic protein-expressing and tumorigenic cell line derived from an avian sarcoma virus-induced rat astrocytoma. 
  • A histidine protein kinase homologue required for regulation of bacterial cell division and differentiation. 
  • A histologic study (including DNA quantification and Ki-67 labeling index) in uveal melanomas after brachytherapy with ruthenium plaques. 
  • A human novel gene DERPC on 16q22.1 inhibits prostate tumor cell growth and its expression is decreased in prostate and renal tumors. 
  • A metalloporphyrin-based superoxide dismutase mimic inhibits adoptive transfer of autoimmune diabetes by a diabetogenic T-cell clone. 
  • A neurally efficient implementation of sensory population decoding. 
  • A noisy linear map underlies oscillations in cell size and gene expression in bacteria. 
  • A novel approach to the measurement of different in vitro leukaemic cell growth parameters: the use of PKH GL fluorescent probes. 
  • A novel human cancer culture model for the study of prostate cancer. 
  • A novel model system for studying the double-edged roles of nitric oxide production in pancreatic cancer growth and metastasis. 
  • A novel neoplastic primary tumor-derived human prostate epithelial cell line. 
  • A novel rodent mammary window of orthotopic breast cancer for intravital microscopy. 
  • A novel role for the cyclin-dependent kinase inhibitor p27(Kip1) in angiotensin II-stimulated vascular smooth muscle cell hypertrophy. 
  • A novel two-component hybrid molecule regulates vascular morphogenesis of the Arabidopsis root. 
  • A pial window model for the intracranial study of human glioma microvascular function. 
  • A polymer-metal composite stent. 
  • A probabilistic model for cell cycle distributions in synchrony experiments. 
  • A rapid fluorescence assay for FtsZ assembly indicates cooperative assembly with a dimer nucleus. 
  • A serially transplantable human giant cell glioblastoma that maintains a near-haploid stem line. 
  • A small-molecule inhibitor of isoprenylcysteine carboxyl methyltransferase with antitumor activity in cancer cells. 
  • A telomerase-immortalized primary human prostate cancer clonal cell line with neoplastic phenotypes. 
  • A truncated isoform of c-Mpl with an essential C-terminal peptide targets the full-length receptor for degradation. 
  • A20 protects mice from lethal liver ischemia/reperfusion injury by increasing peroxisome proliferator-activated receptor-alpha expression. 
  • A20, a modulator of smooth muscle cell proliferation and apoptosis, prevents and induces regression of neointimal hyperplasia. 
  • AAL881, a novel small molecule inhibitor of RAF and vascular endothelial growth factor receptor activities, blocks the growth of malignant glioma. 
  • Abelson virus abrogation of interleukin-3 dependence in a lymphoid cell line. 
  • Abnormal B lymphocyte development, activation, and differentiation in mice that lack or overexpress the CD19 signal transduction molecule. 
  • Absence of TGF-beta receptors and growth inhibitory responses in retinoblastoma cells. 
  • Absence of the CAAX endoprotease Rce1: effects on cell growth and transformation. 
  • Absence of three secreted proteins and presence of a 57-kDa protein related to irreversible arrest of cell growth. 
  • Accelerated repopulation: friend or foe? Exploiting changes in tumor growth characteristics to improve the "efficiency" of radiotherapy. 
  • Acetaminophen toxicity in cultured trout liver cells. I. Morphological alterations and effects on cytochrome P450 1A1. 
  • Acetylcholine promotes the proliferation and collagen gene expression of myofibroblastic hepatic stellate cells. 
  • Aclacinomycin A in the treatment of experimental proliferative vitreoretinopathy. Efficacy and toxicity in the rabbit eye. 
  • Actin cytoskeletal network in aging and cancer. 
  • Activated Akt promotes increased resting T cell size, CD28-independent T cell growth, and development of autoimmunity and lymphoma. 
  • Activated alpha 2-macroglobulin promotes mitogenesis in rat vascular smooth muscle cells by a mechanism that is independent of growth-factor-carrier activity. 
  • Activation and signaling of the Abl tyrosine kinase: bidirectional link with phosphoinositide signaling. 
  • Activation of T lymphocytes for adhesion and cytokine expression by toxin-conjugated anti-CD3 monoclonal antibodies. 
  • Activation of mitogen-activated protein kinase pathway by the antiandrogen hydroxyflutamide in androgen receptor-negative prostate cancer cells. 
  • Activation of monocyte and granulocyte antibody-dependent cytotoxicity by phorbol myristate acetate. 
  • Activation of the sphingomyelin cycle by brefeldin A: effects of brefeldin A on differentiation and implications for a role for ceramide in regulation of protein trafficking. 
  • Activation of vascular smooth muscle cells by TNF and PDGF: overlapping and complementary signal transduction mechanisms. 
  • Activin expression by cultured human retinal pigment epithelial cells. 
  • Activin induces hepatocyte cell growth arrest through induction of the cyclin-dependent kinase inhibitor p15INK4B and Sp1. 
  • Acute lymphoblastic leukaemia in childhood: cell proliferation without rest. 
  • Additive estrogenic activities of a binary mixture of 2',4',6'-trichloro- and 2',3',4',5'-tetrachloro-4-biphenylol. 
  • Adenomatous polyposis coli gene mutation alters proliferation through its beta-catenin-regulatory function in aggressive fibromatosis (desmoid tumor). 
  • Adenovirus-mediated intraarterial delivery of PTEN inhibits neointimal hyperplasia. 
  • Adenovirus-mediated transfer of CCAAT/enhancer-binding protein-alpha identifies a dominant antiproliferative role for this isoform in hepatocytes. 
  • Adjacent positioning of cellular structures enabled by a Cdc42 GTPase-activating protein-mediated zone of inhibition. 
  • Adrenergic control of DNA synthesis in developing rat brain regions: effects of intracisternal administration of isoproterenol. 
  • Adventitial fibroblasts: backstage journeymen. 
  • Aerobic glycolysis suppresses p53 activity to provide selective protection from apoptosis upon loss of growth signals or inhibition of BCR-Abl. 
  • Age-related changes in the cellular composition and epithelial organization of the mouse trachea. 
  • Akt-directed glucose metabolism can prevent Bax conformation change and promote growth factor-independent survival. 
  • Alterations in endothelial superoxide dismutase levels as a function of growth state in vitro. 
  • Altered T-dependent antigen responses and development of autoimmune symptoms in mice lacking E2A in T lymphocytes. 
  • Altered distribution of mitochondria and actin fibers in 3T3 cells cultured on microcarriers. 
  • Altered expression of transforming growth factor-alpha: an early event in renal cell carcinoma development. 
  • Altered genetic response to beta-adrenergic receptor activation in late passage C6 glioma cells. 
  • Altered levels of prothymosin immunoreactive peptide, a growth-related gene product, during liver regeneration after chronic ethanol feeding. 
  • Altered rate of DNA replication in ageing human fibroblast cultures. 
  • Aminoimidazole carboxamide ribonucleoside toxicity: a model for study of pyrimidine starvation. 
  • Amiprilose hydrochloride inhibits porcine aortic smooth muscle cell proliferation in vitro. 
  • An enhancer-blocking element between alpha and delta gene segments within the human T cell receptor alpha/delta locus. 
  • An in vitro analogue of immune dysfunction with altered immunoglobulin production in the aged. 
  • An oligonucleotide decoy for transcription factor E2F inhibits mesangial cell proliferation in vitro. 
  • Analysis of corneal and conjunctival microenvironments using monoclonal antibodies. 
  • Analysis of factors associated with the tumorigenic potential of 12 tumor clones derived from a single rat colon adenocarcinoma. 
  • Analysis of neurogenesis in a mammalian neuroepithelium: proliferation and differentiation of an olfactory neuron precursor in vitro. 
  • Analysis of trans-acting response decoy RNA-mediated inhibition of human immunodeficiency virus type 1 transactivation. 
  • Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer. 
  • Angiogenesis, microvascular architecture, microhemodynamics, and interstitial fluid pressure during early growth of human adenocarcinoma LS174T in SCID mice. 
  • Angiogenesis. 
  • Angiostatin binds ATP synthase on the surface of human endothelial cells. 
  • Angiotensin II stimulates proliferation of adventitial fibroblasts cultured from rat aortic explants. 
  • Angiotensin type 2 receptor is expressed in murine atherosclerotic lesions and modulates lesion evolution. 
  • Anti-bombesin monoclonal antibodies modulate fetal mouse lung growth and maturation in utero and in organ cultures. 
  • Anti-c-myc DNA increases differentiation and decreases colony formation by HL-60 cells. 
  • Anti-human immunodeficiency virus synergism by zidovudine (3'-azidothymidine) and didanosine (dideoxyinosine) contrasts with their additive inhibition of normal human marrow progenitor cells. 
  • Anti-mouse mesangial cell serum induces acute glomerulonephropathy in mice. 
  • Anti-neutrophil chemokine preserves alveolar development in hyperoxia-exposed newborn rats. 
  • Antibodies reactive with the B1 molecule inhibit cell cycle progression but not activation of human B lymphocytes. 
  • Antibody-induced growth inhibition is mediated through immunochemically and functionally distinct epitopes on the extracellular domain of the c-erbB-2 (HER-2/neu) gene product p185. 
  • Antifibrotic and uveitogenic properties of gamma interferon in the rabbit eye. 
  • Antigen delivery by alpha(2)-macroglobulin enhances the cytotoxic T lymphocyte response. 
  • Antitransferrin receptor immunotoxin inhibits proliferating human retinal pigment epithelial cells. 
  • Antitumor agents. 172. Synthesis and biological evaluation of novel deacetamidothiocolchicin-7-ols and ester analogs as antitubulin agents. 
  • Apoptosis and P53 induction in human lung fibroblasts exposed to chromium (VI): effect of ascorbate and tocopherol. 
  • Apoptosis is the mode of cell death caused by carcinogenic chromium. 
  • Apoptotic DNA fragmentation factor maintains chromosome stability in a P53-independent manner. 
  • Apparent cooperative assembly of the bacterial cell division protein FtsZ demonstrated by isothermal titration calorimetry. 
  • Application of a unique monoclonal antibody as a marker for nonproliferating subpopulations of cells of some tissue. 
  • Archaeal cells share common size control with bacteria despite noisier growth and division. 
  • Are all nonproliferating cells similar? 
  • Are cross-bridging structures involved in the bundle formation of intermediate filaments and the decrease in locomotion that accompany cell aging? 
  • Arl2- and Msps-dependent microtubule growth governs asymmetric division. 
  • Arthritis syndromes associated with human T cell lymphotropic virus type I infection. 
  • Articular chondrocyte tenascin-C production and assembly into de novo extracellular matrix. 
  • Artificial surfactant attenuates hyperoxic lung injury in primates. II. Morphometric analysis. 
  • Assembly dynamics of FtsZ rings in Bacillus subtilis and Escherichia coli and effects of FtsZ-regulating proteins. 
  • Association of the protein kinases c-Bcr and Bcr-Abl with proteins of the 14-3-3 family. 
  • Asymmetric cell divisions promote stratification and differentiation of mammalian skin. 
  • Atherosclerosis and cancer: common molecular pathways of disease development and progression. 
  • Atherosclerosis: a cancer of the blood vessels? 
  • Atrial natriuretic polypeptide as a novel antigrowth factor of endothelial cells. 
  • Atrial natriuretic polypeptide inhibits hypertrophy of vascular smooth muscle cells. 
  • Augmentation of umbilical cord blood (UCB) transplantation with ex vivo-expanded UCB cells: results of a phase 1 trial using the AastromReplicell System. 
  • Autocrine and paracrine effects of atrial natriuretic peptide gene transfer on vascular smooth muscle and endothelial cellular growth. 
  • Autocrine growth stimulation by transforming growth factor alpha in asbestos-transformed rat mesothelial cells. 
  • Auxin minimum triggers the developmental switch from cell division to cell differentiation in the Arabidopsis root. 
  • B Cell Subsets Differentially Contribute to the T Cell-Independent Memory Pool. 
  • B-cell homeostasis: digital survival or analog growth? 
  • BMP signaling is required for controlling somatic stem cell self-renewal in the Drosophila ovary. 
  • Bacterial Nucleoid Occlusion: Multiple Mechanisms for Preventing Chromosome Bisection During Cell Division. 
  • Bacterial cell division protein FtsZ assembles into protofilament sheets and minirings, structural homologs of tubulin polymers. 
  • Barriers to productive transfection of trabecular meshwork cells. 
  • Basic fibroblast growth factor downregulates Bcl-2 and promotes apoptosis in MCF-7 human breast cancer cells. 
  • Bayesian Multi-Plate High-Throughput Screening of Compounds. 
  • Bcl-2 accelerates multistep prostate carcinogenesis in vivo. 
  • Beryllium fluoride-induced cell proliferation: a process requiring P21(ras)-dependent activated signal transduction and NF-kappaB-dependent gene regulation. 
  • Beta-adrenergic control of c-fos expression in fetal and neonatal rat tissues: relationship to cell differentiation and teratogenesis. 
  • Beta-adrenoceptor signaling and its control of cell replication in MDA-MB-231 human breast cancer cells. 
  • Biochemical analysis of ++Prospero protein during asymmetric cell division: cortical Prospero is highly phosphorylated relative to nuclear Prospero. 
  • Biochemical correlates of temozolomide sensitivity in pediatric solid tumor xenograft models. 
  • Biologic functions of the G12 subfamily of heterotrimeric g proteins: growth, migration, and metastasis. 
  • Biological basis of bone formation, remodeling, and repair-part I: biochemical signaling molecules. 
  • Biological basis of bone formation, remodeling, and repair-part II: extracellular matrix. 
  • Biological basis of germline mutation: comparisons of spontaneous germline mutation rates among drosophila, mouse, and human. 
  • Biology of small cell lung cancer. 
  • Biomarkers in the endometrium. 
  • Biosynthesis of EGF receptor, transferrin receptor and colligin by cultured human keratinocytes and the effect of retinoic acid. 
  • Bmp4 and Fgf10 play opposing roles during lung bud morphogenesis. 
  • Bombesin-like peptide receptor gene expression, regulation, and function in fetal murine lung. 
  • Bombesin-like peptides and receptors in normal fetal baboon lung: roles in lung growth and maturation. 
  • Bone morphogenetic proteins (BMPs) as regulators of dorsal forebrain development. 
  • Bovine retinal explants cultured in collagen gels. A model system for the study of proliferative retinopathy. 
  • Bradykinin receptor subtype 1 expression and function in prostate cancer. 
  • Brefeldin A promotes hydrolysis of sphingomyelin. 
  • C-myc-induced apoptosis in polycystic kidney disease is Bcl-2 and p53 independent. 
  • CCDC62/ERAP75 functions as a coactivator to enhance estrogen receptor beta-mediated transactivation and target gene expression in prostate cancer cells. 
  • CCI-779 inhibits cell-cycle G2-M progression and invasion of castration-resistant prostate cancer via attenuation of UBE2C transcription and mRNA stability. 
  • CD10/NEP in non-small cell lung carcinomas. Relationship to cellular proliferation. 
  • CD10/neutral endopeptidase 24.11 hydrolyzes bombesin-like peptides and regulates the growth of small cell carcinomas of the lung. 
  • CD10/neutral endopeptidase 24.11 in developing human fetal lung. Patterns of expression and modulation of peptide-mediated proliferation. 
  • CD10/neutral endopeptidase 24.11 regulates fetal lung growth and maturation in utero by potentiating endogenous bombesin-like peptides. 
  • CD19 amplification of B lymphocyte Ca2+ responses: a role for Lyn sequestration in extinguishing negative regulation. 
  • CD22 regulates time course of both B cell division and antibody response. 
  • CD40 mediated activation of gingival and periodontal ligament fibroblasts. 
  • CD7 and CD28 are required for murine CD4+CD25+ regulatory T cell homeostasis and prevention of thyroiditis. 
  • Ca(2+)/calmodulin-dependent kinase is essential for both growth and nuclear division in Aspergillus nidulans. 
  • Cadmium-induced DNA synthesis and cell proliferation in macrophages: the role of intracellular calcium and signal transduction mechanisms. 
  • Calcineurin regulates cyclin D1 accumulation in growth-stimulated fibroblasts. 
  • Calcineurin signaling and muscle remodeling. 
  • Calcium, calmodulin and cell proliferation. 
  • Calmodulin as a regulator of cell growth and gene expression. 
  • Calmodulin is involved in regulation of cell proliferation. 
  • Calmodulin, cell growth and gene expression. 
  • Carbon monoxide promotes hypoxic pulmonary vascular remodeling. 
  • Carcinogenesis in urogenital sites. 
  • Carcinogenicity of a nephrotoxic metabolite of the "nongenotoxic" carcinogen hydroquinone. 
  • Cardiomyocyte cultures with controlled macroscopic anisotropy: a model for functional electrophysiological studies of cardiac muscle. 
  • Cell adhesion peptides alter smooth muscle cell adhesion, proliferation, migration, and matrix protein synthesis on modified surfaces and in polymer scaffolds. 
  • Cell biology and genetics of angiotensin in cardiovascular disease. 
  • Cell cycle control of BRCA2. 
  • Cell cycle effects of nonsteroidal anti-inflammatory drugs and enhanced growth inhibition in combination with gemcitabine in pancreatic carcinoma cells. 
  • Cell cycle protein expression in vascular smooth muscle cells in vitro and in vivo is regulated through phosphatidylinositol 3-kinase and mammalian target of rapamycin. 
  • Cell cycle regulation of human pancreatic cancer by tamoxifen. 
  • Cell cycle studies of cyclocreatine, a new anticancer agent. 
  • Cell death and proliferation and its relation to collagen degradation in uterine involution of rat. 
  • Cell death in cortical development: How much? Why? So what? 
  • Cell density-dependent regulation of cell surface expression of two types of human tumor necrosis factor receptors and its effect on cellular response. 
  • Cell differentiation. 
  • Cell division requires a direct link between microtubule-bound RacGAP and Anillin in the contractile ring. 
  • Cell division without FtsZ--a variety of redundant mechanisms. 
  • Cell division, growth and death. Cell growth: live and let die. 
  • Cell growth regulation in epithelial ovarian cancer. 
  • Cell proliferation and apoptosis in human uterine leiomyomas and myometria. 
  • Cell proliferation is insufficient, but loss of tuberin is necessary, for chemically induced nephrocarcinogenicity. 
  • Cell proliferation is necessary for the determination of male fate in the gonad. 
  • Cell-Cycle-Dependent Chromatin Dynamics at Replication Origins. 
  • Cellular and molecular mechanisms of coronary artery restenosis. 
  • Cellular and molecular studies in brain and nervous system oncology. 
  • Cellular and physiological effects of arginine. 
  • Cellular mechanisms for diminished scarring with aging. 
  • Cellularization in Drosophila melanogaster is disrupted by the inhibition of rho activity and the activation of Cdc42 function. 
  • Ceramide-mediated biology. Determination of structural and stereospecific requirements through the use of N-acyl-phenylaminoalcohol analogs. 
  • Changes in tumor proliferation of rectal cancer induced by preoperative 5-fluorouracil and irradiation. 
  • Characterization of 57 kDa statin as a true marker for growth arrest in tissue by its disappearance from regenerating liver. 
  • Characterization of a human prostate adenocarcinoma cell line (DU 145) as a monolayer culture and as a solid tumor in athymic mice. 
  • Characterization of cord blood natural killer and lymphokine activated killer lymphocytes following ex vivo cellular engineering. 
  • Characterization of free-floating spheres from human trabecular meshwork (HTM) cell culture in vitro. 
  • Characterization of insulin-like growth factor-binding protein-related proteins (IGFBP-rPs) 1, 2, and 3 in human prostate epithelial cells: potential roles for IGFBP-rP1 and 2 in senescence of the prostatic epithelium. 
  • Characterization of senescence- and apoptosis-dependent forms of terminin as derived from a precursor found in replicating and nonreplicating cells. 
  • Characterization of the absence of an unique DNA-binding protein in senescent but not in their young growing and nongrowing counterparts provides the means to mark the final stage of the cellular aging process. 
  • Characterization of the murine BEK fibroblast growth factor (FGF) receptor: activation by three members of the FGF family and requirement for heparin. 
  • Characterization of two populations of statin and the relationship of their syntheses to the state of cell proliferation. 
  • Chemical skin carcinogenesis is prevented in mice by the induced expression of a TGF-beta related transgene. 
  • Chicken calmodulin promoter activity in proliferating and differentiated cells. 
  • Cholera toxin and cell growth: role of membrane gangliosides. 
  • Choline deficiency induces apoptosis in SV40-immortalized CWSV-1 rat hepatocytes in culture. 
  • Chondrogenic differentiation of adipose-derived adult stem cells in agarose, alginate, and gelatin scaffolds. 
  • Chordin and noggin promote organizing centers of forebrain development in the mouse. 
  • Chromium (VI) activates ataxia telangiectasia mutated (ATM) protein. Requirement of ATM for both apoptosis and recovery from terminal growth arrest. 
  • Circumventing tamoxifen resistance in breast cancers using antiestrogens that induce unique conformational changes in the estrogen receptor. 
  • Classification and genetic characterization of pattern-forming Bacilli. 
  • Clearance of antitransferrin receptor immunotoxin from the rabbit eye. 
  • Cleavage-furrow formation without F-actin in Chlamydomonas . 
  • Cloning efficiency of cultured human tumor cell lines measured with the use of a Coulter particle counter. 
  • Cloning of mitogen- and antigen-reactive B lymphocytes on filter paper disks: phenotypic and genotypic analysis of B cell colonies. 
  • Coadministration of IL-12 or IL-10 expression cassettes drives immune responses toward a Th1 phenotype. 
  • Cocaine acutely inhibits DNA synthesis in developing rat brain regions: evidence for direct actions. 
  • Colocalization of WT1 and cell proliferation reveals conserved mechanisms in temperature-dependent sex determination. 
  • Combination of antisense oligonucleotide and low-dose chemotherapy in hematological malignancies. 
  • Combination therapy of inhibitors of epidermal growth factor receptor/vascular endothelial growth factor receptor 2 (AEE788) and the mammalian target of rapamycin (RAD001) offers improved glioblastoma tumor growth inhibition. 
  • Combined effect of chemopreventive agent N-(4-hydroxyphenyl) retinamide (4-HPR) and gamma-radiation on bladder cancer cell lines. 
  • Comparative analyses of mechanistic differences among antiestrogens. 
  • Comparative effects of thermosensitive doxorubicin-containing liposomes and hyperthermia in human and murine tumours. 
  • Comparison of cytostatic sensitivities of L 1210 cells and human stimulated lymphocytes in three cell proliferation assays. 
  • Comparison of human immunodeficiency virus antigens as stimulants for lymphocyte proliferation assays. 
  • Comparison of pleural responses of rats and hamsters to subchronic inhalation of refractory ceramic fibers. 
  • Comparison of pulmonary and pleural responses of rats and hamsters to inhaled refractory ceramic fibers. 
  • Comparison of rectal mucosal proliferation measured by proliferating cell nuclear antigen (PCNA) immunohistochemistry and whole crypt dissection. 
  • Comparison of thymocyte development and cytokine production in CD7-deficient, CD28-deficient and CD7/CD28 double-deficient mice. 
  • Complex response of breast epithelial cell lines to topoisomerase inhibitors. 
  • Conditional expression of SV40 T-antigen in mouse cardiomyocytes facilitates an inducible switch from proliferation to differentiation. 
  • Conjugates of antisense oligonucleotides with the Tat and antennapedia cell-penetrating peptides: effects on cellular uptake, binding to target sequences, and biologic actions. 
  • Constitutive and inducible interleukin 8 expression by hypoxia and acidosis renders human pancreatic cancer cells more tumorigenic and metastatic. 
  • Constitutive expression of placental lactogen in pancreatic beta cells: effects on cell morphology, growth, and gene expression. 
  • Context-specific effects of fibulin-5 (DANCE/EVEC) on cell proliferation, motility, and invasion. Fibulin-5 is induced by transforming growth factor-beta and affects protein kinase cascades. 
  • Continuous human glioma-derived cell lines UC-11MG and UC-302MG. Morphologic, immunocytochemical and chromosomal characterization. 
  • Contribution of mast cells to bacterial clearance and their proliferation during experimental cystitis induced by type 1 fimbriated E. coli. 
  • Control of cell proliferation in senescent cells. 
  • Control of fibroblast senescence and activation of programmed cell death. 
  • Control of phenylalanine hydroxylase synthesis in tissue culture by serum and insulin. 
  • Cooperative regulation of cell proliferation by calcium and calmodulin in Aspergillus nidulans. 
  • Correlation of expression of bombesin-like peptides and receptors with growth inhibition by an anti-bombesin antibody in small-cell lung cancer cell lines. 
  • Cortical reorganization following fertilization of sea urchin eggs: sensitivity to cytochalasin B. 
  • Creation of human tumour cells with defined genetic elements. 
  • Culture of hepatocytes on fructose-modified chitosan scaffolds. 
  • Cyclic AMP modulates the functional plasticity of immature dendritic cells by inhibiting Src-like kinases through protein kinase A-mediated signaling. 
  • Cyclic AMP-dependent protein kinase regulates pseudohyphal differentiation in Saccharomyces cerevisiae. 
  • Cyclocreatine (1-carboxymethyl-2-iminoimidazolidine) inhibits growth of a broad spectrum of cancer cells derived from solid tumors. 
  • Cyclocreatine in cancer chemotherapy. 
  • Cyclosporine inhibition of CH series murine B-cell lymphomas. 
  • Cyclosporine inhibition of a murine B cell lymphoma. 
  • Cystic fibrosis transmembrane regulator regulates uptake of sphingoid base phosphates and lysophosphatidic acid: modulation of cellular activity of sphingosine 1-phosphate. 
  • Cytogenetics and mechanisms of spontaneous abortions: increased apoptosis and decreased cell proliferation in chromosomally abnormal villi. 
  • Cytokine stimulation of aerobic glycolysis in hematopoietic cells exceeds proliferative demand. 
  • Cytopathologic characteristics of permanent cell lines derived from anaplastic human gliomas. 
  • Cytotoxic and metabolic effects of adenosine and adenine on human lymphoblasts. 
  • DAF-18/PTEN inhibits germline zygotic gene activation during primordial germ cell quiescence. 
  • DNA synthesis in strains of Escherichia coli K12 with temperature-sensitive DNA ligase and DNA polymerase I. 
  • Daptomycin-resistant Enterococcus faecalis diverts the antibiotic molecule from the division septum and remodels cell membrane phospholipids. 
  • Daughter-specific transcription factors regulate cell size control in budding yeast. 
  • Daunorubicin treatment in a refined experimental model of proliferative vitreoretinopathy. 
  • Deficiency of either cyclooxygenase (COX)-1 or COX-2 alters epidermal differentiation and reduces mouse skin tumorigenesis. 
  • Dehydroepiandrosterone and analogs inhibit DNA binding of AP-1 and airway smooth muscle proliferation. 
  • Delineating the requirements for spontaneous DNA damage resistance pathways in genome maintenance and viability in Saccharomyces cerevisiae. 
  • Dependence of germinal center B cells on expression of CD21/CD35 for survival. 
  • Derivation of pluripotential embryonic stem cells from murine primordial germ cells in culture. 
  • Desert Hedgehog/Patched 1 signaling specifies fetal Leydig cell fate in testis organogenesis. 
  • Determination of proliferation index in advanced ovarian cancer using quantitative image analysis. 
  • Development and application of basic research techniques in bladder cancer research. 
  • Development and characterization of a fusion protein between thermally responsive elastin-like polypeptide and interleukin-1 receptor antagonist: sustained release of a local antiinflammatory therapeutic. 
  • Development of a YIGSR-peptide-modified polyurethaneurea to enhance endothelialization. 
  • Development of suppressor T lymphocytes for Epstein-Barr virus-induced B-lymphocyte outgrowth during acute infectious mononucleosis: assessment by two quantitative systems. 
  • Developmental neurotoxicity of chlorpyrifos in vivo and in vitro: effects on nuclear transcription factors involved in cell replication and differentiation. 
  • Diagnostic criteria for degenerative, inflammatory, proliferative nonneoplastic and neoplastic liver lesions in medaka (Oryzias latipes): consensus of a National Toxicology Program Pathology Working Group. 
  • Diarylureas are small-molecule inhibitors of insulin-like growth factor I receptor signaling and breast cancer cell growth. 
  • Dietary glycine inhibits angiogenesis during wound healing and tumor growth. 
  • Different G1 cyclins control the timing of cell cycle commitment in mother and daughter cells of the budding yeast S. cerevisiae. 
  • Differential effects of epidermal growth factor, somatomedin-C/insulin-like growth factor I, and transforming growth factor-beta on porcine granulosa cell deoxyribonucleic acid synthesis and cell proliferation. 
  • Differential effects of interleukin-1 alpha, tumor necrosis factor-alpha, indomethacin, hydrocortisone, and macrophage co-culture on the proliferation of human fibroblasts and peritoneal mesothelial cells. 
  • Differential effects of platelet-derived growth factor isotypes on human smooth muscle cell proliferation and migration are mediated by distinct signaling pathways. 
  • Differential regulation of hepatocyte DNA synthesis by cAMP in vitro in vivo. 
  • Differential regulation of the fibroblast growth factor (FGF) family by alpha(2)-macroglobulin: evidence for selective modulation of FGF-2-induced angiogenesis. 
  • Differential response of ventral midbrain and striatal progenitor cells to lesions of the nigrostriatal dopaminergic projection. 
  • Differential toxicity of carbovir and AZT to human bone marrow hematopoietic progenitor cells in vitro. 
  • Differential transcriptional activation of peroxisome proliferator-activated receptor gamma by omega-3 and omega-6 fatty acids in MCF-7 cells. 
  • Differentiation domains of the erythropoietin receptor. 
  • Differentiation of normal marrow and HL60 cells induced by antithymocyte globulin. 
  • Diffusible factors are responsible for differences in nuclease sensitivity among chromatins originating from different cell types. 
  • Discrimination of vanadium from zinc using gene profiling in human bronchial epithelial cells. 
  • Disruption of the Rad9/Rad1/Hus1 (9-1-1) complex leads to checkpoint signaling and replication defects. 
  • Disruption of the gene encoding the mitogen-regulated translational modulator PHAS-I in mice. 
  • Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization. 
  • Dissociation of thymidine incorporation and transferrin receptor expression from cell growth and c-myc accumulation in alpha-interferon-treated cells. 
  • Distinct IL-2 receptor signaling pattern in CD4+CD25+ regulatory T cells. 
  • Distribution of CD133 reveals glioma stem cells self-renew through symmetric and asymmetric cell divisions. 
  • Divergent gene regulation and growth effects by NF-kappa B in epithelial and mesenchymal cells of human skin. 
  • Donor specific bone marrow cells suppress lymphocyte reactivity to donor antigens and differentially modulate TH1 and TH2 cytokine gene expression in the responder cell population. 
  • Down-regulation of neu/HER-2 by interferon-gamma in prostate cancer cells. 
  • Down-regulation of transforming growth factor beta receptor type I, II, and III during liver regeneration. 
  • Dynamic imaging of allogeneic mesenchymal stem cells trafficking to myocardial infarction. 
  • E2F3 activity is regulated during the cell cycle and is required for the induction of S phase. 
  • ELAV protein HuA (HuR) can redistribute between nucleus and cytoplasm and is upregulated during serum stimulation and T cell activation. 
  • ELAV tumor antigen, Hel-N1, increases translation of neurofilament M mRNA and induces formation of neurites in human teratocarcinoma cells. 
  • Early events in human T cell ontogeny. Phenotypic characterization and immunohistologic localization of T cell precursors in early human fetal tissues. 
  • Early wound healing exhibits cytokine surge without evidence of hypoxia. 
  • Ecsit is required for Bmp signaling and mesoderm formation during mouse embryogenesis. 
  • Effect of O6-benzylguanine on nitrogen mustard-induced toxicity, apoptosis, and mutagenicity in Chinese hamster ovary cells. 
  • Effect of antineoplastic agents on smooth muscle cell proliferation in vitro: implications for prevention of restenosis after transluminal angioplasty. 
  • Effect of carbon dioxide on human ovarian carcinoma cell growth. 
  • Effect of epidermal growth factor on glioma cell growth, migration, and invasion in vitro. 
  • Effect of glutamate analogues on brain tumor cell lines. 
  • Effect of growth conditions on the ornithine decarboxylase activity of rat hepatoma cells. 
  • Effect of immunosuppressants on T-cell subsets observed in vivo using carboxy-fluorescein diacetate succinimidyl ester labeling. 
  • Effect of inhibitors of proteolytic enzymes on the growth of normal and polyoma transformed BHK cells. 
  • Effect of ionizing radiation on thymidine uptake, differentiation, and VEGFR2 receptor expression in endothelial cells: the role of VEGF(165). 
  • Effect of streptavidin RGD mutant on the adhesion of endothelial cells. 
  • Effect of thymectomy on human peripheral blood T cell pools in myasthenia gravis. 
  • Effect of vitamin E on tamoxifen-treated breast cancer cells. 
  • Effective treatment of experimental DU-145 prostate cancers with targeted cytotoxic somatostatin analog AN-238. 
  • Effective tumor therapy with plasmid-encoded cytokines combined with in vivo electroporation. 
  • Effects of an oral contraceptive combination with or without androgen on mammary tissues: a study in rats. 
  • Effects of changes in calmodulin levels on cell proliferation. 
  • Effects of chronic exposure to simulated microgravity on skeletal muscle cell proliferation and differentiation. 
  • Effects of ciprofloxacin on eucaryotic pyrimidine nucleotide biosynthesis and cell growth. 
  • Effects of combined treatment with CD25- and CD154-specific monoclonal antibodies in non-human primate allotransplantation. 
  • Effects of cytotoxic T lymphocytes (CTL) directed against a single simian immunodeficiency virus (SIV) Gag CTL epitope on the course of SIVmac239 infection. 
  • Effects of donor age on proteasome activity and senescence in trabecular meshwork cells. 
  • Effects of epidermal growth factor on fibroblast migration through biomimetic hydrogels. 
  • Effects of formaldehyde gas on the respiratory tract of rhesus monkeys. Pathology and cell proliferation. 
  • Effects of insulin-like growth factors I and II and insulin on the immortalized hypothalamic GTI-7 cell line. 
  • Effects of liver growth factors on hepadnavirus replication in chronically infected duck hepatocytes. 
  • Effects of mutant Ran/TC4 proteins on cell cycle progression. 
  • Effects of nitrogen mustard and splenectomy on mouse bone marrow colony formation in vitro. 
  • Effects of the proteasome inhibitor PS-341 on apoptosis and angiogenesis in orthotopic human pancreatic tumor xenografts. 
  • Effects of topical glaucoma drugs on fistulized rabbit conjunctiva. 
  • Effects of treatment with cyclosporine, FK 506, rapamycin, mycophenolic acid, or deoxyspergualin on vascular muscle proliferation in vitro and in vivo. 
  • Efficacy of antisense morpholino oligomer targeted to c-myc in prostate cancer xenograft murine model and a Phase I safety study in humans. 
  • Electrical inhibition of lens epithelial cell proliferation: an additional factor in secondary cataract? 
  • Elevated expression of PCGEM1, a prostate-specific gene with cell growth-promoting function, is associated with high-risk prostate cancer patients. 
  • Elevated frequency of microsatellite mutations in TK6 human lymphoblast clones selected for mutations at the thymidine kinase locus. 
  • Embryonic chick cartilage produces its own somatomedin-like peptide to stimulate cartilage growth in vitro. 
  • Emerging roles for telomerase in neuronal development and apoptosis. 
  • En bloc substitution of the Src homology region 2 domain activates the transforming potential of the c-Abl protein tyrosine kinase. 
  • Endogenous protein kinase-C activation in osteoblast-like cells modulates responsiveness to estrogen and estrogen receptor levels. 
  • Endothelial cell growth on oxygen-containing films deposited by radio-frequency plasmas: the role of surface carbonyl groups. 
  • Endothelial cell surface F1-F0 ATP synthase is active in ATP synthesis and is inhibited by angiostatin. 
  • Endothelial cell-conditioned medium downregulates smooth muscle contractile protein expression. 
  • Endothelial healing in vein grafts: proliferative burst unimpaired by genetic therapy of neointimal disease. 
  • Enforced expression of wild-type p53 curtails the transcription of the O(6)-methylguanine-DNA methyltransferase gene in human tumor cells and enhances their sensitivity to alkylating agents. 
  • Engineering skeletal myoblasts: roles of three-dimensional culture and electrical stimulation. 
  • Enhanced H(2)O(2)-induced cytotoxicity in "epithelioid" smooth muscle cells: implications for neointimal regression. 
  • Enhanced T cell responses due to diacylglycerol kinase zeta deficiency. 
  • Enhanced growth of small bowel in transgenic mice overexpressing bovine growth hormone. 
  • Ependymal/subependymal zone cells of postnatal and adult songbird brain generate both neurons and nonneuronal siblings in vitro and in vivo. 
  • Epidermal growth factor enhances [125I]iodo-follicle-stimulating hormone binding by cultured porcine granulosa cells. 
  • Epidermal growth factor ligand-independent, unregulated, cell-transforming potential of a naturally occurring human mutant EGFRvIII gene. 
  • Epidermal growth factor receptor blockade with C225 plus gemcitabine results in regression of human pancreatic carcinoma growing orthotopically in nude mice by antiangiogenic mechanisms. 
  • Epidermal keratinocytes express the adhesion molecule intercellular adhesion molecule-1 in inflammatory dermatoses. 
  • Epigenetic regulation of CD133 and tumorigenicity of CD133+ ovarian cancer cells. 
  • Epithelial cells are an important source of tenascin in normal and malignant human breast tissue. 
  • Erythropoietin receptor contains both growth-promoting activity and differentiation-promoting activity. 
  • Erythropoietin receptor signals both proliferation and erythroid-specific differentiation. 
  • Escaping G1 restraints on neoplasia--Cdk4 regulation by Ras and NF-kappa B. 
  • Essential amino acid deprivation induces monocytic differentiation of the human HL-60 myeloid leukemia cell line. 
  • Establishment of the DU.528 human lymphohemopoietic stem cell line. 
  • Estrogen stimulation and tamoxifen inhibition of leiomyoma cell growth in vitro and in vivo. 
  • Estrogen-induced mitogenesis of MCF-7 cells does not require the induction of mitogen-activated protein kinase activity. 
  • Estrogen/antiestrogen responsiveness in an in vivo/in vitro model for myometrial tumorigenesis. 
  • Estrogenic activity of a dieldrin/toxaphene mixture in the mouse uterus, MCF-7 human breast cancer cells, and yeast-based estrogen receptor assays: no apparent synergism. 
  • Ethanol induces redox-sensitive cell-cycle inhibitors and inhibits liver regeneration after partial hepatectomy. 
  • Evidence for disruption of sphingolipid metabolism as a contributing factor in the toxicity and carcinogenicity of fumonisins. 
  • Evidence from normal expression and targeted misexpression that bone morphogenetic protein (Bmp-4) plays a role in mouse embryonic lung morphogenesis. 
  • Evidence that myosin does not contribute to force production in chromosome movement. 
  • Ex vivo expansion, maturation, and activation of umbilical cord blood-derived T lymphocytes with IL-2, IL-12, anti-CD3, and IL-7. Potential for adoptive cellular immunotherapy post-umbilical cord blood transplantation. 
  • Expanding the role of NHERF, a PDZ-domain containing protein adapter, to growth regulation. 
  • Expansion of tumor-T cell pairs from fine needle aspirates of melanoma metastases. 
  • Expression of CD44 and variant isoforms in cultured human retinal pigment epithelial cells. 
  • Expression of CXC chemokine receptor-4 enhances the pulmonary metastatic potential of murine B16 melanoma cells. 
  • Expression of TGFalpha in meningiomas. 
  • Expression of an antisense transforming growth factor-beta1 transgene reduces tumorigenicity of EMT6 mammary tumor cells. 
  • Expression of growth factor and growth factor receptor RNA in rat pleural mesothelial cells in culture. 
  • Expression of insulin-like growth factor II in spontaneously immortalized rat mesothelial and spontaneous mesothelioma cells: a potential autocrine role of insulin-like growth factor II. 
  • Expression of penicillin G acylase from the cloned pac gene of Escherichia coli ATCC11105. Effects of pacR and temperature. 
  • Expression of statin, a non-proliferation-dependent nuclear protein, in the postnatal rat brain: evidence for substantial retention of neuroglial proliferative capacity with aging. 
  • Expression of the AT2 receptor developmentally programs extracellular signal-regulated kinase activity and influences fetal vascular growth. 
  • Expression of the non-proliferation-specific protein, statin, in grey matter neuroglia of the aging rat brain. 
  • Expression of transforming growth factor beta type II receptor leads to reduced malignancy in human breast cancer MCF-7 cells. 
  • Extracellular matrix remodeling after balloon angioplasty injury in a rabbit model of restenosis. 
  • FKBP12 is the only FK506 binding protein mediating T-cell inhibition by the immunosuppressant FK506. 
  • Farnesyltransferase inhibitors alter the prenylation and growth-stimulating function of RhoB. 
  • Feedback control of Swe1p degradation in the yeast morphogenesis checkpoint. 
  • Fetal dexamethasone exposure impairs cellular development in neonatal rat heart and kidney: effects on DNA and protein in whole tissues. 
  • Fiber autoradiography of replicating yeast DNA. 
  • Fibrillar systems in cell motility. 
  • Fibroblast growth factor 10 (FGF10) and branching morphogenesis in the embryonic mouse lung. 
  • Fibronectin isoforms in megakaryocytes. 
  • Flavanones structure-related inhibition on TPA-induced tumor promotion through suppression of extracellular signal-regulated protein kinases: involvement of prostaglandin E2 in anti-promotive process. 
  • Flow cytometric detection of lymphocyte proliferation in eyes with immunogenic inflammation. 
  • Flupirtine blocks apoptosis in batten patient lymphoblasts and in human postmitotic CLN3- and CLN2-deficient neurons. 
  • Fly division. 
  • Formin' actin filament bundles. 
  • FtsZ Constriction Force - Curved Protofilaments Bending Membranes. 
  • FtsZ at mid-cell is essential in Escherichia coli until the late stage of constriction. 
  • FtsZ from divergent foreign bacteria can function for cell division in Escherichia coli. 
  • FtsZ, a prokaryotic homolog of tubulin? 
  • Fumonisin inhibition of de novo sphingolipid biosynthesis and cytotoxicity are correlated in LLC-PK1 cells. 
  • Functional characteristics and survival requirements of memory CD4+ T lymphocytes in vivo. 
  • Functional maturation of hPSC-derived forebrain interneurons requires an extended timeline and mimics human neural development. 
  • Further evidence of a decorin-collagen interaction in the disruption of cervical collagen fibers during rat gestation. 
  • G-protein-coupled receptor genes as protooncogenes: constitutively activating mutation of the alpha 1B-adrenergic receptor enhances mitogenesis and tumorigenicity. 
  • GPI-defective monocytes from paroxysmal nocturnal hemoglobinuria patients show impaired in vitro dendritic cell differentiation. 
  • GW112, a novel antiapoptotic protein that promotes tumor growth. 
  • Galectin-1 accumulation in the ovary carcinoma peritumoral stroma is induced by ovary carcinoma cells and affects both cancer cell proliferation and adhesion to laminin-1 and fibronectin. 
  • Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300. 
  • Gene expression and survival changes in Saccharomyces cerevisiae during suspension culture. 
  • Gene expression studies in leiomyomata: new directions for research. 
  • Generation of dendritic cells in vitro from peripheral blood mononuclear cells with granulocyte-macrophage-colony-stimulating factor, interleukin-4, and tumor necrosis factor-alpha for use in cancer immunotherapy. 
  • Genetic deletion of receptor for hyaluronan-mediated motility (Rhamm) attenuates the formation of aggressive fibromatosis (desmoid tumor). 
  • Genetic engineering of vein grafts resistant to atherosclerosis. 
  • Genotypic analysis of B cell colonies by in situ hybridization. Stoichiometric expression of three VH families in adult C57BL/6 and BALB/c mice. 
  • Glial growth factor 2, a soluble neuregulin, directly increases Schwann cell motility and indirectly promotes neurite outgrowth. 
  • Global analysis of gene expression in renal ischemia-reperfusion in the mouse. 
  • Glucocorticoids manifest androgenic activity in a cell line derived from a metastatic prostate cancer. 
  • Glycophase glass revisited: protein adsorption and cell growth on glass surfaces bearing immobilized glycerol monosaccharides. 
  • Growth arrest and DNA damage-inducible protein GADD34 targets protein phosphatase 1 alpha to the endoplasmic reticulum and promotes dephosphorylation of the alpha subunit of eukaryotic translation initiation factor 2. 
  • Growth effects of epidermal growth factor (EGF) and a monoclonal antibody against the EGF receptor on four glioma cell lines. 
  • Growth factor modulation of p53-mediated growth arrest versus apoptosis. 
  • Growth factors can influence cell growth and survival through effects on glucose metabolism. 
  • Growth factors regulate beta-catenin-mediated TCF-dependent transcriptional activation in fibroblasts during the proliferative phase of wound healing. 
  • Growth inhibition and metallothionein induction in cadmium-resistant cells by essential and non-essential metals. 
  • Growth inhibition of a human lung adenocarcinoma cell line by genetic complementation with chromosome 11. 
  • Growth inhibition of human Tenon's capsule fibroblasts and rabbit dermal fibroblasts with non-carcinogenic N-alkylated anthracyclines. 
  • Growth inhibitory effects of aromatic fatty acids on ovarian tumor cell lines. 
  • Growth rate of control and beta-interferon-treated human fibroblast populations over the course of their in vitro life span. 
  • Growth regulation and transformation of ovarian epithelium. 
  • Growth-dependent regulation of cellular ceramides in human T-cells. 
  • Guanine arabinoside as a bone marrow-purging agent. 
  • HEPSIN inhibits cell growth/invasion in prostate cancer cells. 
  • HES1 is a novel downstream modifier of the SHH-GLI3 Axis in the development of preaxial polydactyly. 
  • HIN-1, a putative cytokine highly expressed in normal but not cancerous mammary epithelial cells. 
  • HIV-1 Nef induces proliferation and anchorage-independent growth in podocytes. 
  • HIV-1 induces renal epithelial dedifferentiation in a transgenic model of HIV-associated nephropathy. 
  • Heart regeneration in zebrafish. 
  • Heat shock protein 70 (HSP70) does not prevent the inhibition of cell growth in DU-145 cells treated with TGF-beta1. 
  • Heat shock protein 90 suppresses tumor necrosis factor alpha induced apoptosis by preventing the cleavage of Bid in NIH3T3 fibroblasts. 
  • Helper T cell subsets for immunoglobulin A responses: oral immunization with tetanus toxoid and cholera toxin as adjuvant selectively induces Th2 cells in mucosa associated tissues. 
  • Heparanase and platelet factor-4 induce smooth muscle cell proliferation and migration via bFGF release from the ECM. 
  • Hepatic allograft-derived Kupffer cells regulate T cell response in rats. 
  • Hepatic fibrogenesis requires sympathetic neurotransmitters. 
  • Hepatic hyperplasia in noncirrhotic fatty livers: is obesity-related hepatic steatosis a premalignant condition? 
  • Her4 mediates ligand-dependent antiproliferative and differentiation responses in human breast cancer cells. 
  • Herpes simplex virus (HSV)-mediated ICAM-1 gene transfer abrogates tumorigenicity and induces anti-tumor immunity. 
  • Heterogeneity of Genotypic and phenotypic characteristics of fifteen permanent cell lines derived from human gliomas. 
  • High affinity for farnesyltransferase and alternative prenylation contribute individually to K-Ras4B resistance to farnesyltransferase inhibitors. 
  • High frequency of aberrant p16(INK4A) expression in human breast cancer. 
  • High levels of granulocyte and granulocyte-macrophage colony-stimulating factors in cord blood of normal full-term neonates. 
  • High levels of interleukin-6 are associated with low tumor burden and low growth fraction in multiple myeloma. 
  • High-affinity inhibitors of dihydrofolate reductase: antimicrobial and anticancer activities of 7,8-dialkyl-1,3-diaminopyrrolo[3,2-f]quinazolines with small molecular size. 
  • High-resolution mapping of spontaneous mitotic recombination hotspots on the 1.1 Mb arm of yeast chromosome IV. 
  • Hormonal and metabolic regulation of human chondrosarcoma in vitro. 
  • Hormonal control of oviduct growth and differentiation. 
  • Hormonal stimulation of avian embryonic cartilage growth in vitro: histologic and ultrastructural features. 
  • How cells determine the number of polarity sites. 
  • Human arteries engineered in vitro. 
  • Human bone marrow stromal cell contact and soluble factors have different effects on the survival and proliferation of paediatric B-lineage acute lymphoblastic leukaemic blasts. 
  • Human chorionic gonadotropin increases the concentration of macrophages in neonatal rat testis. 
  • Human dendritic cells, pulsed with either melanoma tumor cell lysates or the gp100 peptide(280-288), induce pairs of T-cell cultures with similar phenotype and lytic activity. 
  • Human fetal liver hematopoietic cell expansion with a novel bioreactor system. 
  • Human intrathymic T cell differentiation. 
  • Human lung cancer cell lines exhibit resistance to retinoic acid treatment. 
  • Human lymphocyte proliferation responses following primary immunization with rabies vaccine as neoantigen. 
  • Human melanoma-mediated inhibition of autologous CD4+ helper tumor-infiltrating lymphocyte growth in vitro. 
  • Human nasopharyngeal-associated lymphoreticular tissues. Functional analysis of subepithelial and intraepithelial B and T cells from adenoids and tonsils. 
  • Human ovarian cancer of the surface epithelium. 
  • Human plasmacytoid dendritic cells activated by CpG oligodeoxynucleotides induce the generation of CD4+CD25+ regulatory T cells. 
  • Human promyelocytic leukemia HL-60 cell proliferation and c-myc protein expression are inhibited by an antisense pentadecadeoxynucleotide targeted against c-myc mRNA. 
  • Human thymic epithelial cells directly induce activation of autologous immature thymocytes. 
  • Human thymic epithelial cells produce interleukin 1. 
  • Hyalocytes synthesize and secrete inhibitors of retinal pigment epithelial cell proliferation in vitro. 
  • Hydroxytyrosol, a natural molecule occurring in olive oil, induces cytochrome c-dependent apoptosis. 
  • IL-13 and IL-1beta promote lung fibroblast growth through coordinated up-regulation of PDGF-AA and PDGF-Ralpha. 
  • IL-4 induces differentiation and expansion of Th2 cytokine-producing eosinophils. 
  • IL-7 enhances the survival and maintains the size of naive T cells. 
  • IQGAP1, a novel vascular endothelial growth factor receptor binding protein, is involved in reactive oxygen species--dependent endothelial migration and proliferation. 
  • Identification and characterization of small molecule inducers of epidermal keratinocyte differentiation 
  • Identification of arachidonic acid as a mediator of sphingomyelin hydrolysis in response to tumor necrosis factor alpha. 
  • Identification of murine extra-embryonic endodermal cells by reaction with teratocarcinoma basement membrane antiserum. 
  • Identification of resting cells by dual-parameter flow cytometry of statin expression and DNA content. 
  • Identification of the TBX5 transactivating domain and the nuclear localization signal. 
  • Immune status assay (ISA): a noninvasive procedure for studying allograft rejection. 
  • Immunogenicity of HIV-1 Env and Gag in baboons using a DNA prime/protein boost regimen. 
  • Immunohistochemical analysis of statin in colorectal adenocarcinoma, polyps, and normal mucosa. 
  • Impact of fetal nicotine exposure on development of rat brain regions: critical sensitive periods or effects of withdrawal? 
  • Impaired proliferation and tumorigenicity induced by CCAAT/enhancer-binding protein. 
  • Implication of mitochondrial involvement in apoptotic activity of fragile histidine triad gene: application of synchronous luminescence spectroscopy. 
  • Improved flow cytometric analysis of the budding yeast cell cycle. 
  • In Toto Imaging of Dynamic Osteoblast Behaviors in Regenerating Skeletal Bone. 
  • In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populations. 
  • In the absence of extrinsic signals, nutrient utilization by lymphocytes is insufficient to maintain either cell size or viability. 
  • In vitro and in vivo antitumor effect of the anti-CD26 monoclonal antibody 1F7 on human CD30+ anaplastic large cell T-cell lymphoma Karpas 299. 
  • In vitro and in vivo investigations for the development of cytostatic methylhydrazones. 
  • In vitro characteristics of Tenon's fibroblast lines derived from pediatric and adult eyes do not fully explain pediatric glaucoma surgery failure: a preliminary report. 
  • In vitro culture of epithelial cells derived from urogenital tissues. 
  • In vitro determination of thymidine-3H labeling index in human solid tumors. 
  • In vitro keratinocyte antiproliferant effect of Centella asiatica extract and triterpenoid saponins. 
  • In vitro toxicology of fumonisins and the mechanistic implications. 
  • In vivo characterization of Escherichia coli ftsZ mutants: effects on Z-ring structure and function. 
  • In vivo growth conditions suppress the expression of ganglioside GM2 and favour that of lacto series gangliosides in the human glioma D-54MG cell line. 
  • In-vivo impaired T helper 1 cell development in submandibular lymph nodes due to IL-12 deficiency following antigen injection into the anterior chamber of the eye. 
  • Inactivation of Icmt inhibits transformation by oncogenic K-Ras and B-Raf. 
  • Increased dentate granule cell neurogenesis following amygdala kindling in the adult rat. 
  • Increased expression of Drosophila tetraspanin, Tsp68C, suppresses the abnormal proliferation of ytr-deficient and Ras/Raf-activated hemocytes. 
  • Indian hedgehog as a progesterone-responsive factor mediating epithelial-mesenchymal interactions in the mouse uterus. 
  • Induction and spontaneous regression of pulmonary neuroendocrine cell hyperplasia in a hamster model. 
  • Induction of apoptosis by the novel retinoid AHPN in human T-cell lymphoma cells involves caspase-dependent and independent pathways. 
  • Induction of autocrine epidermal growth factor receptor ligands in human keratinocytes by insulin/insulin-like growth factor-1. 
  • Induction of differentiation in human myeloblastic leukemia ML-1 cells by heptachlor, a chlorinated hydrocarbon insecticide. 
  • Induction of internucleosomal DNA fragmentation by carcinogenic chromate: relationship to DNA damage, genotoxicity, and inhibition of macromolecular synthesis. 
  • Induction of mitogenic signalling in the 1LN prostate cell line on exposure to submicromolar concentrations of cadmium+. 
  • Induction of p21waf1 expression and growth inhibition by transforming growth factor beta involve the tumor suppressor gene DPC4 in human pancreatic adenocarcinoma cells. 
  • Inhibition of Bmp signaling affects growth and differentiation in the anagen hair follicle. 
  • Inhibition of CYP1A1 enzyme activity in mouse hepatoma cell culture by soybean isoflavones. 
  • Inhibition of aldehyde dehydrogenase expands hematopoietic stem cells with radioprotective capacity. 
  • Inhibition of calcium/calmodulin kinase II alpha subunit expression results in epileptiform activity in cultured hippocampal neurons. 
  • Inhibition of cell proliferation by an RNA ligand that selectively blocks E2F function. 
  • Inhibition of cultured human RPE cell proliferation and lysyl hydroxylase activity by hydroxy derivatives of minoxidil. 
  • Inhibition of fetal thymic caspases abrogates the consequences of adenosine deaminase deficiency. 
  • Inhibition of growth of MX-1, MCF-7-MIII and MDA-MB-231 human breast cancer xenografts after administration of a targeted cytotoxic analog of somatostatin, AN-238. 
  • Inhibition of growth of OV-1063 human epithelial ovarian cancers and c- jun and c- fos oncogene expression by bombesin antagonists. 
  • Inhibition of growth of human malignant glioblastoma in nude mice by antagonists of bombesin/gastrin-releasing peptide. 
  • Inhibition of human corneal epithelium with immunotoxin 454A12-rRA. 
  • Inhibition of human subconjunctival fibroblast proliferation by immunotoxin. 
  • Inhibition of neuronal maturation in primary hippocampal neurons from tau deficient mice. 
  • Inhibition of platelet-derived growth factor-BB-induced fibroblast proliferation by plasmin-activated alpha 2-macroglobulin is mediated via an alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein-dependent mechanism. 
  • Inhibition of proliferating lens epithelium with antitransferrin receptor immunotoxin. 
  • Inhibition of rat arterial smooth muscle cell proliferation by heparin. In vivo studies with anticoagulant and nonanticoagulant heparin. 
  • Inhibition of the growth of pre-established subcutaneous tumor nodules of human prostate cancer cells by single injection of the recombinant adenovirus p53 expression vector. 
  • Inhibition of tumor growth by targeting tumor endothelium using a soluble vascular endothelial growth factor receptor. 
  • Initial amplification of duck hepatitis B virus covalently closed circular DNA after in vitro infection of embryonic duck hepatocytes is increased by cell cycle progression. 
  • Initial stages of tumor cell-induced angiogenesis: evaluation via skin window chambers in rodent models. 
  • Insulin-like growth factor binding protein-3 induces early apoptosis in malignant prostate cancer cells and inhibits tumor formation in vivo. 
  • Insulin-like growth factor-I gene expression in the tibial epiphyseal growth plate of growth hormone-treated uremic rats. 
  • Insulin-like growth factor-I is a serum component stimulating growth of human neuroblastoma. 
  • Insulin-like growth factor-I is expressed by avian flexor tendon cells. 
  • Intact nitric oxide synthase II gene is required for interferon-beta-mediated suppression of growth and metastasis of pancreatic adenocarcinoma. 
  • Interaction of atrial natriuretic polypeptide and angiotensin II on protooncogene expression and vascular cell growth. 
  • Interaction of macrophages and lymphocytes for lymphokine production and cellular proliferation. 
  • Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen. 
  • Interferon gamma (IFNgamma) gene transfer of an EMT6 tumor that is poorly responsive to IFNgamma stimulation: increase in tumor immunogenicity is accompanied by induction of a mouse class II transactivator and class II MHC. 
  • Interferon production in mixed cultures of murine leukocytes and syngeneic L1210 leukemia cells. 
  • Interleukin-6 protects liver against warm ischemia/reperfusion injury and promotes hepatocyte proliferation in the rodent. 
  • Interplay between SCARECROW, GA and LIKE HETEROCHROMATIN PROTEIN 1 in ground tissue patterning in the Arabidopsis root. 
  • Interplay between septin organization, cell cycle and cell shape in yeast. 
  • Intracellular third loop domain of angiotensin II type-2 receptor. Role in mediating signal transduction and cellular function. 
  • Intratumoral heterogeneity in primary breast carcinoma: study of concurrent parameters. 
  • Intravital imaging of mouse embryos. 
  • Involvement of an actomyosin contractile ring in Saccharomyces cerevisiae cytokinesis. 
  • Involvement of the mt1 melatonin receptor in human breast cancer. 
  • Involvement of two endonuclease III homologs in the base excision repair pathway for the processing of DNA alkylation damage in Saccharomyces cerevisiae. 
  • Iron metabolism and cell membranes. III. Iron-induced alterations in HeLa cells. 
  • Is fipronil safer than chlorpyrifos? Comparative developmental neurotoxicity modeled in PC12 cells. 
  • Isolation and characterization of a novel human bladder cancer cell line: BK10. 
  • Isolation and transplantation of autologous circulating endothelial cells into denuded vessels and prosthetic grafts: implications for cell-based vascular therapy. 
  • Isolation of a transplantable cell line induced by the MC29 avian leukosis virus. 
  • Isoproterenol downregulation of statin-related gene expression in the rat parotid gland. 
  • JAK2 is required for induction of the murine DUB-1 gene. 
  • Kappa editing rescues autoreactive B cells destined for deletion in mice transgenic for a dual specific anti-laminin Ig. 
  • Keratinocyte growth factor--just another mitogen or the "Holy Grail" that regulates liver regeneration? 
  • Kinesin proteins: a phylum of motors for microtubule-based motility. 
  • Lack of cyclin-dependent kinase 4 inhibits c-myc tumorigenic activities in epithelial tissues. 
  • Lack of viral escape and defective in vivo activation of human immunodeficiency virus type 1-specific cytotoxic T lymphocytes in rapidly progressive infection. 
  • Levels of p53 protein increase with maturation in human hematopoietic cells. 
  • Ligation of prostate cancer cell surface GRP78 activates a proproliferative and antiapoptotic feedback loop: a role for secreted prostate-specific antigen. 
  • Light scattering measurements of subcellular structure provide noninvasive early detection of chemotherapy-induced apoptosis. 
  • Limiting lumens: a new role for Cdc42. 
  • Lipopolysaccharide stimulates mitochondrial biogenesis via activation of nuclear respiratory factor-1. 
  • Liver regeneration 3: Regulation of signal transduction during liver regeneration. 
  • Local production of TGF beta1 inhibits cerebral edema, enhances TNF-alpha induced apoptosis and improves survival in a murine glioma model. 
  • Localization of a cryptic binding site for tenascin on fibronectin. 
  • Long- and short-lived murine hematopoietic stem cell clones individually identified with retroviral integration markers. 
  • Long-term effects of intermittent interleukin 2 therapy in patients with HIV infection: characterization of a novel subset of CD4(+)/CD25(+) T cells. 
  • Long-term primary culture of epithelial cells from rainbow trout Oncorhynchus mykiss) liver. 
  • Long-term pulmonary responses of three laboratory rodent species to subchronic inhalation of pigmentary titanium dioxide particles. 
  • Long-term repopulating ability of xenogeneic transplanted human fetal liver hematopoietic stem cells in sheep. 
  • Long-term stabilization of vein graft wall architecture and prolonged resistance to experimental atherosclerosis after E2F decoy oligonucleotide gene therapy. 
  • Loss of PTEN/MMAC1/TEP in EGF receptor-expressing tumor cells counteracts the antitumor action of EGFR tyrosine kinase inhibitors. 
  • Low-dose genistein induces cyclin-dependent kinase inhibitors and G(1) cell-cycle arrest in human prostate cancer cells. 
  • LvNotch signaling plays a dual role in regulating the position of the ectoderm-endoderm boundary in the sea urchin embryo. 
  • Lymphocyte development and function in the absence of retinoic acid-related orphan receptor alpha. 
  • Lymphocyte development and selection in germinal centers. 
  • Lymphoma models for B cell activation and tolerance. V. Anti-Ig mediated growth inhibition is reversed by phorbol myristate acetate but does not involve changes in cytosolic free calcium. 
  • MCA106 fibrosarcoma cells transduced with granulocyte/macrophage colony-stimulating factor are not superior to the wild-type cells in suppressing the growth of hepatic metastases. 
  • Macrophage-mediated fungistasis in vitro: requirements for intracellular and extracellular cytotoxicity. 
  • Maintenance of DNA content and erbB-2 alterations in intraductal and invasive phases of mammary cancer. 
  • Male-specific cell migration into the developing gonad. 
  • Mammalian dwarfins are phosphorylated in response to transforming growth factor beta and are implicated in control of cell growth. 
  • Marshall Urist Award. Interstitial collagenase gene expression correlates with in vitro invasion in human chondrosarcoma. 
  • Mating-type-specific and nonspecific PAK kinases play shared and divergent roles in Cryptococcus neoformans. 
  • Matrix metalloproteinase activity modulates tumor size, cell motility, and cell invasiveness in murine aggressive fibromatosis. 
  • Measurement of cellular proliferation within the vitreous during experimental proliferative vitreoretinopathy. 
  • Measurement of the growth parameters of precursor B-acute lymphoblastic leukaemic cells in co-culture with bone marrow stromal cells; detection of two cd10 positive populations with different proliferative capacities and survival. 
  • Mechanism of apoptosis and determination of cellular fate in chromium(VI)-exposed populations of telomerase-immortalized human fibroblasts. 
  • Mechanisms of self-tolerance and autoimmunity: from whole-animal phenotypes to molecular pathways. 
  • Melatonin synergizes with retinoic acid in the prevention and regression of breast cancer. 
  • Mesothelial cell proliferation induced by intrapleural instillation of man-made fibers in rats and hamsters. 
  • Met and hepatocyte growth factor/scatter factor expression in human gliomas. 
  • Metabolic and functional characterization of human adipose-derived stem cells in tissue engineering. 
  • Metabolism of chloroform by cytochrome P450 2E1 is required for induction of toxicity in the liver, kidney, and nose of male mice. 
  • Metals and disorders of cell accumulation: modulation of apoptosis and cell proliferation. 
  • Metastatic behavior and cell surface properties of HT-29 human colon carcinoma variant cells selected for their differential expression of sialyl-dimeric Le(x)-antigen. 
  • Methylation of deoxycytidine incorporated by excision-repair synthesis of DNA. 
  • Mice deficient in inducible nitric oxide synthase are susceptible to experimental autoimmune uveoretinitis. 
  • Mice lacking the p53-effector gene Gadd45a develop a lupus-like syndrome. 
  • MicroRNA miR396 Regulates the Switch between Stem Cells and Transit-Amplifying Cells in Arabidopsis Roots. 
  • Microarray analysis of E-box binding-related gene expression in young and replicatively senescent human fibroblasts. 
  • Microglial function in human APOE3 and APOE4 transgenic mice: altered arginine transport. 
  • Mimetics of caloric restriction include agonists of lipid-activated nuclear receptors. 
  • Minoxidil inhibits ocular cell proliferation and lysyl hydroxylase activity. 
  • Mitogenesis, cell migration, and loss of focal adhesions induced by tenascin-C interacting with its cell surface receptor, annexin II. 
  • Mitogenic effect of neuropeptide Y in rat vascular smooth muscle cells. 
  • Mitosis is required for production of murine leukemia virus and structural proteins during de novo infection. 
  • Mode of action: disruption of brain cell replication, second messenger, and neurotransmitter systems during development leading to cognitive dysfunction--developmental neurotoxicity of nicotine. 
  • Modeling killing and repopulation kinetics of subclinical cancer: direct calculations from clinical data. 
  • Modulation of cell growth and differentiation by ceramide. 
  • Modulation of etoposide (VP-16) cytotoxicity by verapamil or cyclosporine in multidrug-resistant human leukemic cell lines and normal bone marrow. 
  • Modulation of immunologic responses to HIV-1MN recombinant gp160 vaccine by dose and schedule of administration. National Institute of Allergy and Infectious Diseases AIDS Vaccine Evaluation Group. 
  • Modulation of oncogene and tumor suppressor gene expression in a hamster model of chronic lung injury with varying degrees of pulmonary neuroendocrine cell hyperplasia. 
  • Modulation of phosphatidylinositol 3-kinase signaling reduces intimal hyperplasia in aortocoronary saphenous vein grafts. 
  • Modulation of potassium transport in cultured retinal pigment epithelium and retinal glial cells by serum and epidermal growth factor. 
  • Molecular characterization of the human delta opioid receptor in lung cancer. 
  • Molecular genetic dissection of myosin heavy chain function. 
  • Molecular mechanisms of vascular renin-angiotensin system in myointimal hyperplasia. 
  • Molecular therapies for vascular diseases. 
  • Monoclonal antibody 4F2 reactive with basal layer keratinocytes: studies in the normal and a hyperproliferative state. 
  • Monocyte adhesion in patients with bone marrow fibrosis is required for the production of fibrogenic cytokines. Potential role for interleukin-1 and TGF-beta. 
  • Monocytoid differentiation of freshly isolated human myeloid leukemia cells and HL-60 cells induced by the glutamine antagonist acivicin. 
  • Most of the yeast genomic sequences are not essential for cell growth and division. 
  • Motifs within the CLN3 protein: modulation of cell growth rates and apoptosis. 
  • Mouse germ cell clusters form by aggregation as well as clonal divisions. 
  • Mouse retinal pigmented epithelial cell lines retain their phenotypic characteristics after transfection with human papilloma virus: a new tool to further the study of RPE biology. 
  • Mps1 defines a proximal blastemal proliferative compartment essential for zebrafish fin regeneration. 
  • Multiple autocrine growth factors modulate vascular smooth muscle cell growth response to angiotensin II. 
  • Multiple cyclic AMP receptors are linked to adenylyl cyclase in Dictyostelium. 
  • Multiple facets of Arabidopsis seedling development require indole-3-butyric acid-derived auxin. 
  • Multivariate proteomic analysis of murine embryonic stem cell self-renewal versus differentiation signaling. 
  • Mutagenicity and carcinogenicity of biological reactive intermediate's derived from a "non-genotoxic" carcinogen. 
  • Mutant forms of growth factor-binding protein-2 reverse BCR-ABL-induced transformation. 
  • Mutants of FtsZ targeting the protofilament interface: effects on cell division and GTPase activity. 
  • Mutational analysis of the p21/WAF1/CIP1/SDI1 coding region in human tumor cell lines. 
  • Mutational fingerprints of aging. 
  • Mutations of the BRAF gene in human cancer. 
  • Myoblast proliferation and differentiation on fibronectin-coated self assembled monolayers presenting different surface chemistries. 
  • Myocardial injury-induced fibroblast proliferation facilitates retroviral-mediated gene transfer to the rat heart in vivo. 
  • Myocardial volume and organization are changed by failure of addition of secondary heart field myocardium to the cardiac outflow tract. 
  • Myogenic stem cell function is impaired in mice lacking the forkhead/winged helix protein MNF. 
  • Myosins motor Miranda. 
  • Myotonic muscular dystrophy: morphology, histochemistry, and growth characteristics of cultured skin fibroblasts. 
  • N-myc regulates parkin expression. 
  • NADPH oxidase promotes NF-kappaB activation and proliferation in human airway smooth muscle. 
  • NF-kappaB RelA opposes epidermal proliferation driven by TNFR1 and JNK. 
  • NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia. 
  • NMDA receptor dependence of kindling and mossy fiber sprouting: evidence that the NMDA receptor regulates patterning of hippocampal circuits in the adult brain. 
  • NOX5 NAD(P)H oxidase regulates growth and apoptosis in DU 145 prostate cancer cells. 
  • Natural variation in CDC28 underlies morphological phenotypes in an environmental yeast isolate. 
  • Neem oil inhibits two-cell embryo development and trophectoderm attachment and proliferation in vitro. 
  • Nef stimulates proliferation of glomerular podocytes through activation of Src-dependent Stat3 and MAPK1,2 pathways. 
  • Neonatal chlorpyrifos administration elicits deficits in immune function in adulthood: a neural effect? 
  • Neonates support lymphopenia-induced proliferation. 
  • Network building: transcriptional circuits in the root. 
  • Neural and glial-mediated effects of growth factors acting via tyrosine kinase receptors on luteinizing hormone-releasing hormone neurons. 
  • Neuronal control of cardiac and hepatic macromolecule synthesis in the neonatal rat: effects of sympathectomy. 
  • New murine cell line derived from a spontaneous lung tumor induces paraneoplastic syndromes. 
  • New roles for pyruvate kinase M2: working out the Warburg effect. 
  • New tumor markers of testis cancer. 
  • Nicotine increases size and severity of experimental choroidal neovascularization. 
  • Nitric oxide modulation of human leukemia cell differentiation and gene expression. 
  • Nitric oxide modulation of the growth and differentiation of freshly isolated acute non-lymphocytic leukemia cells. 
  • Nitric oxide-dependent ribosomal RNA cleavage is associated with inhibition of ribosomal peptidyl transferase activity in ANA-1 murine macrophages. 
  • Nitric oxide-generating polymers reduce platelet adhesion and smooth muscle cell proliferation. 
  • Nmyc plays an essential role during lung development as a dosage-sensitive regulator of progenitor cell proliferation and differentiation. 
  • Nonmyeloablative regimen preserves "niches" allowing for peripheral expansion of donor T-cells. 
  • Norepinephrine regulates hepatic innate immune system in leptin-deficient mice with nonalcoholic steatohepatitis. 
  • Notch 1 signaling regulates peripheral T cell activation. 
  • Novel human alpha1a-adrenoceptor single nucleotide polymorphisms alter receptor pharmacology and biological function. 
  • Novel origins of lineage founder cells in the direct-developing sea urchin Heliocidaris erythrogramma. 
  • Novel therapeutic approaches to advanced prostate cancer. 
  • Nox4 mediates TGF-beta1-induced retinoblastoma protein phosphorylation, proliferation, and hypertrophy in human airway smooth muscle cells. 
  • NuMA-microtubule interactions are critical for spindle orientation and the morphogenesis of diverse epidermal structures. 
  • Nuclear oncoprotein expression as a function of lineage, differentiation stage, and proliferative status of normal human hematopoietic cells. 
  • Nucleocytoplasmic trafficking of G2/M regulators in yeast. 
  • Numb antagonizes Notch signaling to specify sibling neuron cell fates. 
  • Obligatory role for cooperative signaling by pre-TCR and Notch during thymocyte differentiation. 
  • Oligonucleotide enhanced cytotoxicity of Idarubicin for lymphoma cells. 
  • One tissue, two fates: molecular genetic events that underlie testis versus ovary development. 
  • Optimization and characterization of the capillary human tumor clonogenic cell assay. 
  • Organization and cell differentiation in lateral roots of Arabidopsis thaliana. 
  • Osteopontin inhibits expression of cytochrome c oxidase in RAW 264.7 murine macrophages. 
  • Osteopontin regulates ubiquitin-dependent degradation of Stat1 in murine mammary epithelial tumor cells. 
  • Osteopontin-dependent CD44v6 expression and cell adhesion in HepG2 cells. 
  • Out of Eden: stem cells and their niches. 
  • Oval cells compensate for damage and replicative senescence of mature hepatocytes in mice with fatty liver disease. 
  • Overcoming Chronic Rejection-Can it B? 
  • Overexpression of G protein-coupled receptor kinase-2 in smooth muscle cells attenuates mitogenic signaling via G protein-coupled and platelet-derived growth factor receptors. 
  • Overexpression of G protein-coupled receptor kinase-2 in smooth muscle cells reduces neointimal hyperplasia. 
  • Overexpression of heme oxygenase-1 in human pulmonary epithelial cells results in cell growth arrest and increased resistance to hyperoxia. 
  • Overexpression of human catalase inhibits proliferation and promotes apoptosis in vascular smooth muscle cells. 
  • Overlapping high-resolution copy number alterations in cancer genomes identified putative cancer genes in hepatocellular carcinoma. 
  • Oxidative stress and oval cell accumulation in mice and humans with alcoholic and nonalcoholic fatty liver disease. 
  • PCGEM1, a prostate-specific gene, is overexpressed in prostate cancer. 
  • PDGF-BB, IGF-I and mechanical load stimulate DNA synthesis in avian tendon fibroblasts in vitro. 
  • PDGF-stimulated fibroblast proliferation is enhanced synergistically by receptor-recognized alpha 2-macroglobulin. 
  • PHAS proteins as mediators of the actions of insulin, growth factors and cAMP on protein synthesis and cell proliferation. 
  • PINA is essential for growth and positively influences NIMA function in Aspergillus nidulans. 
  • PMEPA1, an androgen-regulated NEDD4-binding protein, exhibits cell growth inhibitory function and decreased expression during prostate cancer progression. 
  • Parent stem cells can serve as niches for their daughter cells. 
  • Partial suppression of anchorage-independent growth and tumorigenicity in immunodeficient mice by transfection of the H-2 class I gene H-2Ld into a human colon cancer cell line (HCT). 
  • Pathogenesis of hemangioma. 
  • Pathways of cell signaling in hyperoxia. 
  • Patterning the primary root in Arabidopsis. 
  • Pdgfr-alpha mediates testis cord organization and fetal Leydig cell development in the XY gonad. 
  • Pentosan polysulfate decreases prostate smooth muscle proliferation and extracellular matrix turnover. 
  • Peripheral blood mononuclear cells from patients with bullous pemphigoid have an increased frequency of response to synthetic peptides encoded by BPAG1. 
  • Pertussis toxin triggers rapid second messenger production in human T lymphocytes. 
  • Phagocytic cells synthesize 19-nor-10-keto-25-hydroxyvitamin D3, a metabolite that may induce differentiation of the human monoblastic cell line U937. 
  • Pharmacologic purging of malignant T cells from human bone marrow using 9-beta-D-arabinofuranosylguanine. 
  • Pharmacological uncoupling of androgen receptor-mediated prostate cancer cell proliferation and prostate-specific antigen secretion. 
  • Phenylbutyrate-induced G1 arrest and apoptosis in myeloid leukemia cells: structure-function analysis. 
  • Phospholipid-binding protein Cts1 controls septation and functions coordinately with calcineurin in Cryptococcus neoformans. 
  • Photocrosslinkable polyvinyl alcohol hydrogels that can be modified with cell adhesion peptides for use in tissue engineering. 
  • Physiologic importance of protein phosphatase inhibitors. 
  • Physiological electric fields control the G1/S phase cell cycle checkpoint to inhibit endothelial cell proliferation. 
  • Pin1 regulates the timing of mammalian primordial germ cell proliferation. 
  • Pleural dosimetry and pathobiological responses in rats and hamsters exposed subchronically to MMVF 10a fiberglass. 
  • Podocyte cell cycle regulation and proliferation in collapsing glomerulopathies. 
  • Polyamines as intermediates in developmental neurotoxic events. 
  • Polycystic kidney disease in SBM transgenic mice: role of c-myc in disease induction and progression. 
  • Polyol and vacuole formation in cultured canine lens epithelial cells. 
  • Positional cloning of a temperature-sensitive mutant emmental reveals a role for sly1 during cell proliferation in zebrafish fin regeneration. 
  • Possible role for vascular cell proliferation in cerebral vasospasm after subarachnoid hemorrhage. 
  • Postreceptor signal transduction by cyclic adenosine monophosphate and the Ca2+-calmodulin complex. 
  • Potential role of WAF1/Cip1/p21 as a mediator of TGF-beta cytoinhibitory effect. 
  • Potentiation of bleomycin lethality by anticalmodulin drugs: a role for calmodulin in DNA repair. 
  • Potentiation of signal transduction mitogenesis and cellular proliferation upon binding of receptor-recognized forms of alpha2-macroglobulin to 1-LN prostate cancer cells. 
  • Preclinical evidence for therapeutic efficacy of selective estrogen receptor modulators for uterine leiomyoma. 
  • Preferential synthesis of yeast mitochondrial DNA in alpha factor-arrested cells. 
  • Prognotic significance of pretreatment proliferative activity in adult acute leukemia. 
  • Programmed population control by cell-cell communication and regulated killing. 
  • Programming of brainstem serotonin transporter development by prenatal glucocorticoids. 
  • Proinflammatory actions of thromboxane receptors to enhance cellular immune responses. 
  • Proliferating cell nuclear antigen and mitotic activity in rectal cancer: predictor of response to preoperative irradiation. 
  • Proliferation and apoptosis of fibroblasts and smooth muscle cells in rat uterine cervix throughout gestation and the effect of the antiprogesterone onapristone. 
  • Proliferation and differentiation defects during lung development in corticotropin-releasing hormone-deficient mice. 
  • Proliferation index in various stages of breast cancer determined by Ki-67 immunostaining. 
  • Proliferative activity at colonic anastomoses as determined by statin. A nonproliferation-specific nuclear protein. 
  • Proliferative activity of colonic mucosa at different distances from primary adenocarcinoma as determined by the presence of statin: a nonproliferation-specific nuclear protein. 
  • Proliferative index determination in prostatic carcinoma tissue: is there any additional prognostic value greater than that of Gleason score, ploidy and pathological stage? 
  • Promotion by sodium barbital induces early development but does not increase the multiplicity of hereditary renal tumors in Eker rats. 
  • Prostate-specific expression of p53(R172L) differentially regulates p21, Bax, and mdm2 to inhibit prostate cancer progression and prolong survival. 
  • Protease-activated receptor-2 signaling triggers dendritic cell development. 
  • Protein kinase A operates a molecular switch that governs yeast pseudohyphal differentiation. 
  • Protein kinase B controls transcriptional programs that direct cytotoxic T cell fate but is dispensable for T cell metabolism. 
  • Protein kinase activity and identification of a toxic effector domain of the target of rapamycin TOR proteins in yeast. 
  • Protein tyrosine phosphatase PTP1B is involved in neuroendocrine differentiation of prostate cancer. 
  • Pulmonary responses of mice, rats, and hamsters to subchronic inhalation of ultrafine titanium dioxide particles. 
  • Purification and characterization of the yeast-expressed erythropoietin mutant Epo (R103A), a specific inhibitor of human primary hematopoietic cell erythropoiesis. 
  • Purification and partial characterization of a human hematopoietic precursor population. 
  • Purification of alpha-sarcin and an antifungal protein from Aspergillus giganteus by blue sepharose CL-6B affinity chromatography. 
  • Purine toxicity in human lymphoblasts. 
  • Quantification of cellular proliferation in experimental proliferative vitreoretinopathy. 
  • Quantitative assessment of growth stimulating activity of the vitreous during PVR. 
  • Quantitative graft integration of fetal hippocampal transplants labeled with 5' bromodeoxyuridine into normal adult hippocampus. 
  • Quiescent phenotype of tumor-specific CD8+ T cells following immunization. 
  • RUNX3 inhibits cell proliferation and induces apoptosis by reinstating transforming growth factor beta responsiveness in esophageal adenocarcinoma cells. 
  • Receptor binding, endocytosis, and mitogenesis of insulin-like growth factors I and II in fetal rat brain neurons. 
  • Receptor-like kinase ACR4 restricts formative cell divisions in the Arabidopsis root. 
  • Receptor-mediated monocytoid differentiation of human promyelocytic cells by tumor necrosis factor: synergistic actions with interferon-gamma and 1,25-dihydroxyvitamin D3. 
  • Receptors that induce erythroid differentiation of Ba/F3 cells: structural requirements and effect on STAT5 binding. 
  • Recognition and lysis of human melanoma by a CD3+, CD4+, CD8- T-cell clone restricted by HLA-A2. 
  • Recombinant adenovirus vector expressing wild-type p53 is a potent inhibitor of prostate cancer cell proliferation. 
  • Red blood cell arginase suppresses Jurkat (T cell) proliferation by depleting arginine. 
  • Redirecting migration of T cells to chemokine secreted from tumors by genetic modification with CXCR2. 
  • Reduced expression of transforming growth factor beta type I receptor contributes to the malignancy of human colon carcinoma cells. 
  • Reduced synthesis of pp60src and expression of the transformation-related phenotype in interferon-treated Rous sarcoma virus-transformed rat cells. 
  • Reduction of human prostate tumor vascularity by the alpha1-adrenoceptor antagonist terazosin. 
  • Reentry into the cell cycle of differentiated skeletal myocytes. 
  • Regenerative proliferation in inner ear sensory epithelia from adult guinea pigs and humans. 
  • Regulated heat shock protein 27 expression in human retinal pigment epithelium. 
  • Regulated spindle orientation buffers tissue growth in the epidermis. 
  • Regulation of 12-lipoxygenase by cytokines in vascular smooth muscle cells. 
  • Regulation of Division and Differentiation of Plant Stem Cells. 
  • Regulation of Kv1 subunit expression in oligodendrocyte progenitor cells and their role in G1/S phase progression of the cell cycle. 
  • Regulation of P311 expression by Met-hepatocyte growth factor/scatter factor and the ubiquitin/proteasome system. 
  • Regulation of apoptosis in normal and malignant ovarian epithelial cells by transforming growth factor beta. 
  • Regulation of cell cycle progression by calcium/calmodulin-dependent pathways. 
  • Regulation of cell division and of tyrosinase in B16 melanoma cells by imidazole: a possible role for the concept of metabolite gene regulation in mammalian cells. 
  • Regulation of cytosolic phospholipase A2 activity in macrophages stimulated with receptor-recognized forms of alpha 2-macroglobulin: role in mitogenesis and cell proliferation. 
  • Regulation of de novo purine synthesis in human lymphoblasts. Similar rates of de novo synthesis during growth by normal cells and mutants deficient in hypoxanthine-guanine phosphoribosyltransferase activity. 
  • Regulation of growth of normal ovarian epithelial cells and ovarian cancer cell lines by transforming growth factor-beta. 
  • Regulation of plant stem cell quiescence by a brassinosteroid signaling module. 
  • Regulation of proliferation and platelet-derived growth factor expression in palmar fibromatosis (Dupuytren contracture) by mechanical strain. 
  • Regulation of the macrophage population in postnatal rat testis. 
  • Regulation of translation and transcription of messenger RNA during early embryonic development. 
  • Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions. 
  • Regulatory functions of calmodulin. 
  • Regulatory roles of cyclin dependent kinase phosphorylation in cell cycle control. 
  • Relationship between expression of coactivators and corepressors of hormone receptors and resistance of ovarian cancers to growth regulation by steroid hormones. 
  • Replication of yeast chromosomal DNA. 
  • Repression of B7.2 on self-reactive B cells is essential to prevent proliferation and allow Fas-mediated deletion by CD4(+) T cells. 
  • Repression of the human papillomavirus E6 gene initiates p53-dependent, telomerase-independent senescence and apoptosis in HeLa cervical carcinoma cells. 
  • Reproducibility and variability of the rectal mucosal proliferation index using proliferating cell nuclear antigen immunohistochemistry. 
  • Requirement for reactive oxygen species in serum-induced and platelet-derived growth factor-induced growth of airway smooth muscle. 
  • Requirement of transforming growth factor-beta (TGF-beta) type II receptor for TGF-beta-induced proliferation and growth inhibition. 
  • Requirements for the kit receptor tyrosine kinase during regeneration of zebrafish fin melanocytes. 
  • Resistance of an adenosine kinase-deficient human lymphoblastoid cell line to effects of deoxyadenosine on growth, S-adenosylhomocysteine hydrolase inactivation, and dATP accumulation. 
  • Resistance to tyrosine kinase inhibition by mutant epidermal growth factor receptor variant III contributes to the neoplastic phenotype of glioblastoma multiforme. 
  • Response of bone marrow to MC29 avian leukosis virus in vitro. 
  • Response of chick-embryo kidney cells in vitro to two avian tumor viruses. 
  • Responses of vascular endothelial cells to angiogenic signaling are important for tumor cell survival. 
  • Restoration of p53 function leads to tumour regression in vivo. 
  • Resveratrol arrests the cell division cycle at S/G2 phase transition. 
  • Retinal vasoproliferative tumors: surgical management and histological findings. 
  • Retinoids and retinoic acid receptors regulate growth arrest and apoptosis in human mammary epithelial cells and modulate expression of CBP/p300. 
  • Retroviral vector-mediated gene transfer into umbilical cord blood-derived megakaryocyte and platelet progenitors. 
  • Reversal of apoptosis by the leukaemia-associated E2A-HLF chimaeric transcription factor. 
  • Rho kinase promotes alloimmune responses by regulating the proliferation and structure of T cells. 
  • Robust control of mitotic spindle orientation in the developing epidermis. 
  • Rodent model of reproductive tract leiomyomata: characterization and use in preclinical therapeutic studies. 
  • Role for ETS domain transcription factors Pea3/Erm in mouse lung development. 
  • Role for c-jun N-terminal kinase in treatment-refractory acute myeloid leukemia (AML): signaling to multidrug-efflux and hyperproliferation. 
  • Role of T-bet in commitment of TH1 cells before IL-12-dependent selection. 
  • Role of decreased levels of lipid phosphate phosphatase-1 in accumulation of lysophosphatidic acid in ovarian cancer. 
  • Role of folylpolyglutamates in biochemical modulation of fluoropyrimidines by leucovorin. 
  • Role of ornithine decarboxylase and the polyamines in nervous system development: a review. 
  • Role of pericellular matrix in development of a mechanically functional neocartilage. 
  • Role of prostacyclin in the cardiovascular response to thromboxane A2. 
  • Role of small GTP-binding proteins in lovastatin-induced cataracts. 
  • Role of vascular mitogens in subarachnoid hemorrhage-associated cerebral vasculopathy. 
  • Roles of CCAAT/enhancer-binding proteins in regulation of liver regenerative growth. 
  • S-adenosylhomocysteine toxicity in normal and adenosine kinase-deficient lymphoblasts of human origin. 
  • SLE nephritis is associated with an oligoclonal expansion of intrarenal T cells. 
  • STAT-3 overexpression and p21 up-regulation accompany impaired regeneration of fatty livers. 
  • SW1PerS: Sliding windows and 1-persistence scoring; discovering periodicity in gene expression time series data. 
  • Saccharomyces cerevisiae virulence phenotype as determined with CD-1 mice is associated with the ability to grow at 42 degrees C and form pseudohyphae. 
  • Scaffold-mediated symmetry breaking by Cdc42p. 
  • Schedule and concentration-dependent induction of apoptosis in leukemia cells by nitric oxide. 
  • Secondary aqueous humor stimulates the proliferation of cultured bovine corneal endothelial cells. 
  • Sedimentation and volume analysis of human bone marrow. 
  • Selective inhibition of heterotrimeric Gs signaling. Targeting the receptor-G protein interface using a peptide minigene encoding the Galpha(s) carboxyl terminus. 
  • Selective inhibition of matrix metalloproteinase-14 blocks tumor growth, invasion, and angiogenesis. 
  • Septin ring assembly involves cycles of GTP loading and hydrolysis by Cdc42p. 
  • Serial labeling index determination as a predictor of response in human solid tumors. 
  • Serum withdrawal induces apoptotic cell death in Ki-ras transformed but not in normal differentiated thyroid cells. 
  • Severely impaired B lymphocyte proliferation, survival, and induction of the c-Myc:Cullin 1 ubiquitin ligase pathway resulting from CD22 deficiency on the C57BL/6 genetic background. 
  • Signaling by wingless in Drosophila. 
  • Signaling in and out: control of cell division and differentiation in the shoot and root. 
  • Signaling, desensitization, and trafficking of G protein-coupled receptors revealed by green fluorescent protein conjugates. 
  • Simian virus 40-induced retinopathy in the rat. 
  • Similarities in long-term alloreactive T cell lines propagated from transfusion-enhanced and control-rejecting rat renal allografts. 
  • Site-specific mutations of FtsZ--effects on GTPase and in vitro assembly. 
  • Sites of B-cell activation in vivo. 
  • Smad3 has a critical role in TGF-beta-mediated growth inhibition and apoptosis in colonic epithelial cells. 
  • Smad3 signaling critically regulates fibroblast phenotype and function in healing myocardial infarction. 
  • Small-molecule nicotinamide for ex vivo expansion of umbilical cord blood. 
  • Smooth muscle cell growth in photopolymerized hydrogels with cell adhesive and proteolytically degradable domains: synthetic ECM analogs for tissue engineering. 
  • Smooth muscle cell migration and proliferation are mediated by distinct phases of activation of the intracellular messenger mitogen-activated protein kinase. 
  • Solitary eosinophilic granuloma invading the clivus of an adult: case report. 
  • Soluble factor in normal tissues that stimulates high-molecular-weight sialoglycoprotein production by human colon carcinoma cells. 
  • Somatic inactivation of Nf1 in hematopoietic cells results in a progressive myeloproliferative disorder. 
  • Spatial distribution of proliferating cells in avian sarcoma virus-induced gliomas. 
  • Spatiotemporal regulation of cell-cycle genes by SHORTROOT links patterning and growth. 
  • Sphingolipid breakdown products: anti-proliferative and tumor-suppressor lipids. 
  • Sphingolipids--the enigmatic lipid class: biochemistry, physiology, and pathophysiology. 
  • Sry and the testis: molecular pathways of organogenesis. 
  • Sry induces cell proliferation in the mouse gonad. 
  • Statin expression associated with terminally differentiating and postreplicative lens epithelial cells. 
  • Statin, a protein specifically present in nonproliferating cells, is a phosphoprotein and forms a complex with a 45-kilodalton serine/threonine kinase. 
  • Statin--a novel marker of nonproliferation. Expression in nonneoplastic lymphoid tissues and follicular lymphomas. 
  • Stem cell factor is a potent synergistic factor in hematopoiesis. 
  • Stem cells, cancer, and cancer stem cells. 
  • Steroids for restenosis: strike three! 
  • Stimulation of in vitro proliferation of murine lymphocytes by synthetic oligodeoxynucleotides. 
  • Stimulation of ovarian tumor cell proliferation with monocyte products including interleukin-1, interleukin-6, and tumor necrosis factor-alpha. 
  • Stimulation of thymocyte proliferation by phosphorothioate DNA oligonucleotides. 
  • Stress-induced secretion of growth inhibitors: a novel tumor suppressor function of p53. 
  • Stromelysin-3 suppresses tumor cell apoptosis in a murine model. 
  • Structural and elemental characterization of heart cells grown in a collagen matrix. 
  • Structural evidence that the P/Q domain of ZipA is an unstructured, flexible tether between the membrane and the C-terminal FtsZ-binding domain. 
  • Studies investigating pretransplant donor-specific blood transfusion, rapamycin, and the CD154-specific antibody IDEC-131 in a nonhuman primate model of skin allotransplantation. 
  • Studies on the inhalation toxicology of two fiberglasses and amosite asbestos in the Syrian golden hamster. Part II. Results of chronic exposure. 
  • Studies on the inhalation toxicology of two fiberglasses and amosite asbestos in the syrian golden hamster. Part I. Results of a subchronic study and dose selection for a chronic study. 
  • Studies on the role of basic fibroblast growth factor in vivo: inability of neutralizing antibodies to block tumor growth. 
  • Subsets of murine lung fibroblasts express membrane-bound and soluble IL-4 receptors. Role of IL-4 in enhancing fibroblast proliferation and collagen synthesis. 
  • Summary: present and future challenges for stem cell research. 
  • Suppression of antiproliferative effects of tumor necrosis factor by transfection of cells with human platelet-derived growth factor B/c-sis gene. 
  • Suppression of diacylglycerol levels by antibodies reactive with the c-erbB-2 (HER-2/neu) gene product p185c-erbB-2 in breast and ovarian cancer cell lines. 
  • Suppression of human corneal epithelial proliferation with breast carcinoma immunotoxin. 
  • Suppression of tumor formation in vivo by expression of the JE gene in malignant cells. 
  • Suppression of tumorigenesis and induction of p15(ink4b) by Smad4/DPC4 in human pancreatic cancer cells. 
  • Sustained release of nerve growth factor from biodegradable polymer microspheres. 
  • Symmetry breaking in plants: molecular mechanisms regulating asymmetric cell divisions in Arabidopsis. 
  • Synergistic interaction between anti-p185HER-2 ricin A chain immunotoxins and radionuclide conjugates for inhibiting growth of ovarian and breast cancer cells that overexpress HER-2. 
  • Syntaxin 1A is transiently expressed in fetal lung mesenchymal cells: potential developmental roles. 
  • Systemic production of human granulocyte colony-stimulating factor in nonhuman primates by transplantation of genetically modified myoblasts. 
  • T cell repertoire development in humans with SCID after nonablative allogeneic marrow transplantation. 
  • T helper 2-dominant antilymphoma immune response is associated with fatal outcome. 
  • T-independent activation-induced cytidine deaminase expression, class-switch recombination, and antibody production by immature/transitional 1 B cells. 
  • TBX5 is required for embryonic cardiac cell cycle progression. 
  • TGF-beta through Smad3 signaling stimulates vascular smooth muscle cell proliferation and neointimal formation. 
  • Targeted cytotoxic analogue of bombesin/gastrin-releasing peptide inhibits the growth of H-69 human small-cell lung carcinoma in nude mice. 
  • Targeted developmental overexpression of calmodulin induces proliferative and hypertrophic growth of cardiomyocytes in transgenic mice. 
  • Targeted expression of calmodulin increases ventricular cardiomyocyte proliferation and deoxyribonucleic acid synthesis during mouse development. 
  • Targeting Gbeta gamma signaling in arterial vascular smooth muscle proliferation: a novel strategy to limit restenosis. 
  • Targeting cancer stem cells through L1CAM suppresses glioma growth. 
  • Targeting of cytotoxic somatostatin analog AN-238 to somatostatin receptor subtypes 5 and/or 3 in experimental pancreatic cancers. 
  • Targeting the endothelium in cancer--the importance of the interaction of hemostatic mechanisms and the vascular wall for tumor growth and angiogenesis. 
  • Targeting wide-range oncogenic transformation via PU24FCl, a specific inhibitor of tumor Hsp90. 
  • Telomerase activity in normal leukocytes and in hematologic malignancies. 
  • Telomere shortening in cultured autografts of patients with burns. 
  • Terminal bronchioles harbor a unique airway stem cell population that localizes to the bronchoalveolar duct junction. 
  • Tethered-TGF-beta increases extracellular matrix production of vascular smooth muscle cells. 
  • The Abl family kinases: mechanisms of regulation and signaling. 
  • The Aspergillus fumigatus septins play pleiotropic roles in septation, conidiation, and cell wall stress, but are dispensable for virulence. 
  • The B7-2 (B70) costimulatory molecule expressed by monocytes and activated B lymphocytes is the CD86 differentiation antigen. 
  • The Bcr-Abl tyrosine kinase activates mitogenic signaling pathways and stimulates G1-to-S phase transition in hematopoietic cells. 
  • The C-terminal linker of Escherichia coli FtsZ functions as an intrinsically disordered peptide. 
  • The COBRA family of putative GPI-anchored proteins in Arabidopsis. A new fellowship in expansion. 
  • The Ca(2+) channel antagonists mibefradil and pimozide inhibit cell growth via different cytotoxic mechanisms. 
  • The FtsZ protofilament and attachment of ZipA--structural constraints on the FtsZ power stroke. 
  • The Galpha protein Gpa2 controls yeast differentiation by interacting with kelch repeat proteins that mimic Gbeta subunits. 
  • The IL-2 receptor gamma c chain does not function as a subunit shared by the IL-4 and IL-13 receptors. Implication for the structure of the IL-4 receptor. 
  • The Ras-related protein AGS1/RASD1 suppresses cell growth. 
  • The Ribbon-Helix-Helix Domain Protein CdrS Regulates the Tubulin Homolog ftsZ2 To Control Cell Division in Archaea. 
  • The SABRE gene is required for normal cell expansion in Arabidopsis. 
  • The SCARECROW gene regulates an asymmetric cell division that is essential for generating the radial organization of the Arabidopsis root. 
  • The SHORT-ROOT gene controls radial patterning of the Arabidopsis root through radial signaling. 
  • The TOR kinases link nutrient sensing to cell growth. 
  • The TOR signal transduction cascade controls cellular differentiation in response to nutrients. 
  • The accelerated repopulation of a murine fibrosarcoma, FSA-II, during the fractionated irradiation and the linear-quadratic model. 
  • The angiotensin II type 2 (AT2) receptor antagonizes the growth effects of the AT1 receptor: gain-of-function study using gene transfer. 
  • The angiotensin II type I receptor-associated protein, ATRAP, is a transmembrane protein and a modulator of angiotensin II signaling. 
  • The antiproliferative effect of a transferrin-toxin on human retinal pigment epithelial cells and rabbit fibroblasts. 
  • The arterial wall and the atherosclerotic lesion. 
  • The beta-interferon-mediated antimitogenic state resembles the anti-viral state. 
  • The c-kit proto-oncogene receptor is expressed on a subset of human CD3-CD4-CD8- (triple-negative) thymocytes. 
  • The cellular and physiological mechanism of wing-body scaling in Manduca sexta. 
  • The differentiation process of intestinal epithelial cells is associated with the appearance of statin, a non-proliferation-specific nuclear protein. 
  • The discontinuous nature of propagation in normal canine cardiac muscle. Evidence for recurrent discontinuities of intracellular resistance that affect the membrane currents. 
  • The distribution of intimal white blood cells in the normal rabbit aorta. 
  • The dual ErbB1/ErbB2 inhibitor, lapatinib (GW572016), cooperates with tamoxifen to inhibit both cell proliferation- and estrogen-dependent gene expression in antiestrogen-resistant breast cancer. 
  • The dynamics of bone marrow stromal cells in the proliferation of multipotent hematopoietic progenitors by substance P: an understanding of the effects of a neurotransmitter on the differentiating hematopoietic stem cell. 
  • The effect of antibodies and immunotoxins reactive with HER-2/neu on growth of ovarian and breast cancer cell lines. 
  • The effect of culture density and proliferation rate on the expression of ouabain-sensitive Na/K ATPase pumps in cultured human retinal pigment epithelium. 
  • The effect of octreotide on hepatic regeneration in rats. 
  • The effect of total-body irradiation on corneal neovascularization in the Fischer 344 rat after chemical cauterization. 
  • The effects of hepatic cryosurgery on tumor growth in the liver. 
  • The emerging concept of vascular remodeling. 
  • The engine driving the ship: metabolic steering of cell proliferation and death. 
  • The exon junction complex component Magoh controls brain size by regulating neural stem cell division. 
  • The function of multiple IkappaB : NF-kappaB complexes in the resistance of cancer cells to Taxol-induced apoptosis. 
  • The gene encoding bone morphogenetic protein 8B is required for the initiation and maintenance of spermatogenesis in the mouse. 
  • The growth-dependent expression of angiotensin II type 2 receptor is regulated by transcription factors interferon regulatory factor-1 and -2. 
  • The hormone receptor GUCY2C suppresses intestinal tumor formation by inhibiting AKT signaling. 
  • The in vitro growth of murine high proliferative potential-colony forming cells is not enhanced by growth in a low oxygen atmosphere. 
  • The influence of base sequence on the immunological properties of defined oligonucleotides. 
  • The macrophage as an antineoplastic surveillance cell: biological perspectives. 
  • The mechanism of nucleotide excision repair-mediated UV-induced mutagenesis in nonproliferating cells. 
  • The morphogenesis checkpoint: how yeast cells watch their figures. 
  • The morphologic response of cell lines derived from human gliomas to dibutyryl adenosine 3':5'-cyclic monophosphate. 
  • The nonopisthokont septins: How many there are, how little we know about them, and how we might learn more. 
  • The novel tubulin-binding drug BTO-956 inhibits R3230AC mammary carcinoma growth and angiogenesis in Fischer 344 rats. 
  • The production and characterization of murine monoclonal antibodies to human Gadd45 raised against a recombinant protein. 
  • The protein synthetic surge in response to mitogen triggers high glycolytic enzyme levels in human lymphocytes and occurs prior to DNA synthesis. 
  • The quick and the dead: microbial demography at the yeast thermal limit. 
  • The regulatory light chain of nonmuscle myosin is encoded by spaghetti-squash, a gene required for cytokinesis in Drosophila. 
  • The relationship of expression of statin, the nuclear protein of nonproliferating cells, to the differentiation and cell cycle of astroglia in cultures and in situ. 
  • The role of CD45RO in antithymocyte globulin's stimulation of primitive haemopoietic cells. 
  • The role of Smad3 in mediating mouse hepatic stellate cell activation. 
  • The role of cAMP-dependent signaling in receptor-recognized forms of alpha 2-macroglobulin-induced cellular proliferation. 
  • The role of cytoplasmic deoxycytidine kinase in the mitochondrial effects of the anti-human immunodeficiency virus compound, 2',3'-dideoxycytidine. 
  • The role of peptide growth factors in epithelial ovarian cancer. 
  • The role of receptors for complement in the induction of polyclonal B-cell proliferation and differentiation. 
  • The septin cortex at the yeast mother-bud neck. 
  • The spindle assembly and spindle position checkpoints. 
  • The synthetic phosphagen cyclocreatine phosphate inhibits the growth of a broad spectrum of solid tumors. 
  • The thymic microenvironment. Characterization of in vitro differentiation of the IT26R21 rat thymic epithelial cell line. 
  • The tumor dormant state. 
  • The tumor dormant state. Comparison of L5178Y cells used to establish dormancy with those that emerge after its termination. 
  • The tumor dormant state. Quantitation of L5178Y cells and host immune responses during the establishment and course of dormancy in syngeneic DBA/2 mice. 
  • The winged helix transcription factor MFH1 is required for proliferation and patterning of paraxial mesoderm in the mouse embryo. 
  • The yeast HSM3 gene is not involved in DNA mismatch repair in rapidly dividing cells. 
  • Three populations of cells with dendritic morphology exist in peripheral blood, only one of which is infectable with human immunodeficiency virus type 1. 
  • Thromboxane augmentation of alloreactive T cell function. 
  • Thymic model for examining BRCA2 expression and function. 
  • Thymosin fraction 5 inhibits the proliferation of the rat neuroendocrine MMQ pituitary adenoma and C6 glioma cell lines in vitro. 
  • Tissue interactions pattern the mesenchyme of the embryonic mouse lung. 
  • Tissue transglutaminase is expressed as a host response to tumor invasion and inhibits tumor growth. 
  • Tissue-culture surfaces with mixtures of aminated and fluorinated functional groups. Part 2. Growth and function of transgenic rat insulinoma cells (betaG I/17). 
  • Topology and control of the cell-cycle-regulated transcriptional circuitry. 
  • Transcription factor LKLF is sufficient to program T cell quiescence via a c-Myc-dependent pathway. 
  • Transcriptional control of tissue formation throughout root development. 
  • Transfection of cells with transforming growth factor-alpha leads to cellular resistance to the antiproliferative effects of tumor necrosis factor. 
  • Transfection of ovarian cancer cells with tumor necrosis factor-alpha (TNF-alpha) antisense mRNA abolishes the proliferative response to interleukin-1 (IL-1) but not TNF-alpha. 
  • Transfer of human chromosomes via human minisegregant cells into mouse cells and the quantitation of the expression of hypoxanthine phosphoribosyltransferase in the hybrids. 
  • Transfer of the Septin Ring to Cytokinetic Remnants in ER Stress Directs Age-Sensitive Cell-Cycle Re-entry. 
  • Transforming growth factor alpha and epidermal growth factor receptor in reactive and malignant mesothelial proliferations. 
  • Transforming growth factor beta 1 can induce CIP1/WAF1 expression independent of the p53 pathway in ovarian cancer cells. 
  • Transforming growth factor beta 1 dysregulation in a human oral carcinoma tumour progression model. 
  • Transforming growth factor beta mediates the estrogen induced inhibition of UMR106 cell growth. 
  • Transforming growth factor beta3 promotes fascial wound healing in a new animal model. 
  • Transforming growth factor-beta inhibits proliferation of human ovarian cancer cells obtained from ascites. 
  • Transforming growth factor-beta-mediated p15(INK4B) induction and growth inhibition in astrocytes is SMAD3-dependent and a pathway prominently altered in human glioma cell lines. 
  • Transgenic targeting of a dominant negative corepressor to liver blocks basal repression by thyroid hormone receptor and increases cell proliferation. 
  • Transplantation of thymus tissue in complete DiGeorge syndrome. 
  • Treatment of human glioma and medulloblastoma tumor lines in athymic mice with diaziquone and diaziquone-based drug combinations. 
  • Trisomy 8 mosaicism: selective growth advantage of normal cells vs. growth disadvantage of trisomy 8 cells. 
  • Tumor necrosis factor alpha as an autocrine and paracrine growth factor for ovarian cancer: monokine induction of tumor cell proliferation and tumor necrosis factor alpha expression. 
  • Tumor proliferation in rectal cancer following preoperative irradiation. 
  • Tumor suppressor TSC1 is critical for T-cell anergy. 
  • Tumor suppressor gene Smad4/DPC4, its downstream target genes, and regulation of cell cycle. 
  • Two new loci, PLEIADE and HYADE, implicate organ-specific regulation of cytokinesis in Arabidopsis. 
  • Unconventional Cell Division Cycles from Marine-Derived Yeasts. 
  • Uncoupling of genomic and epigenetic signals in the maintenance and inheritance of heterochromatin domains in fission yeast. 
  • Uninvolved skin from psoriatic patients develops signs of involved psoriatic skin after being grafted onto nude mice. 
  • Unusual DNA sequences associated with the ends of yeast chromosomes. 
  • Up-regulation of the alpha2-macroglobulin signaling receptor on rheumatoid synovial fibroblasts. 
  • Use of lung toxicity and lung particle clearance to estimate the maximum tolerated dose (MTD) for a fiber glass chronic inhalation study in the rat. 
  • Vaccination with dendritic cells inhibits the growth of hepatic metastases in B6 mice. 
  • Vaginal administration of low-dose conjugated estrogens: systemic absorption and effects on the endometrium. 
  • Vascular endothelial growth factor receptor-1 modulates vascular endothelial growth factor-mediated angiogenesis via nitric oxide. 
  • Vascular morphogenesis: tales of two syndromes. 
  • Vascular proliferation and atherosclerosis: new perspectives and therapeutic strategies. 
  • Vascular renin-angiotensin system and vascular protection. 
  • Vascular smooth muscle cell hypertrophy vs. hyperplasia. Autocrine transforming growth factor-beta 1 expression determines growth response to angiotensin II. 
  • Vasoactive intestinal peptide (VIP) inhibits the proliferation of bone marrow progenitors through the VPAC1 receptor. 
  • Vertebrate Reproduction. 
  • Virulence of Cryptococcus neoformans. Regulation of capsule synthesis by carbon dioxide. 
  • Visualizing nuclear migration during conidiophore development in Aspergillus nidulans and Aspergillus oryzae: multinucleation of conidia occurs through direct migration of plural nuclei from phialides and confers greater viability and early germination in Aspergillus oryzae. 
  • Vitamin D inhibits proliferation of human uterine leiomyoma cells via catechol-O-methyltransferase. 
  • Vitamin E succinate inhibits human prostate cancer cell growth via modulating cell cycle regulatory machinery. 
  • Wing morphogenesis in Lepidoptera. 
  • YC-1-mediated vascular protection through inhibition of smooth muscle cell proliferation and platelet function. 
  • Yeast Cdc42 functions at a late step in exocytosis, specifically during polarized growth of the emerging bud. 
  • [125I]iodo-epidermal growth factor binding and mitotic responsiveness of porcine granulosa cells are modulated by differentiation and follicle-stimulating hormone. 
  • [A study of epithelial cell kinetics of the odontogenic keratocyst]. 
  • [Experimental approaches for gene therapy modification of vascular remodeling]. 
  • [Inhibitation of tumor angiogenesis, growth and metastasis by blocking VEGF paracrine pathway]. 
  • [Quantitative study of the cellular nuclear DNA contents in odontogenic cysts and ameloblastoma]. 
  • [The relationship between drug sensitivity and expression of drug resistance gene mutations in non-small cell lung cancer]. 
  • alpha 2-Macroglobulin, complement, and biologic defense: antigens, growth factors, microbial proteases, and receptor ligation. 
  • alpha 2u-Globulin nephropathy, renal cell proliferation, and dosimetry of inhaled tert-butyl alcohol in male and female F-344 rats. 
  • beta-Catenin stabilization dysregulates mesenchymal cell proliferation, motility, and invasiveness and causes aggressive fibromatosis and hyperplastic cutaneous wounds. 
  • beta-arrestins regulate mitogenic signaling and clathrin-mediated endocytosis of the insulin-like growth factor I receptor. 
  • eNOS-overexpressing endothelial cells inhibit platelet aggregation and smooth muscle cell proliferation in vitro. 
  • hMad4, c-Myc endogenous inhibitor, induces a replicative senescence-like state when overexpressed in human fibroblasts. 
  • p38 mitogen-activated protein kinase regulates growth factor-induced mitogenesis of rat pulmonary myofibroblasts. 
  • p53 and mdm-2 expression in malignant melanoma: an immunocytochemical study of expression of p53, mdm-2, and markers of cell proliferation in primary versus metastatic tumors. 
  • pp60v-src kinase overexpression leads to cellular resistance to the antiproliferative effects of tumor necrosis factor. 
• 

  Keywords of People

  • Allori, Alexander C, Associate Professor of Surgery, Surgery, Plastic, Maxillofacial, and Oral Surgery
  • Bejsovec, Amy, Associate Professor of Biology, Biology
  • Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Bradford, William Dalton, Professor of Pathology, Pathology
  • Buckley, Anne Frances, Assistant Professor of Pathology, Pathology
  • Buckley, Rebecca Hatcher, James Buren Sidbury Distinguished Professor of Pediatrics, in the School of Medicine, Immunology
  • Chen, Jun, Professor of Medicine, Duke Cancer Institute
  • Cianciolo, George James, Associate Professor Emeritus of Pathology, Pathology
  • Ciofani, Maria, Associate Professor of Immunology, Immunology
  • Erickson, Harold Paul, James B. Duke Distinguished Professor of Cell Biology, Cell Biology
  • Freemark, Michael Scott, Robert C. Atkins, M.D. and Veronica Atkins Distinguished Professor of Pediatrics, in the School of Medicine, Pediatrics, Endocrinology
  • Hartemink, Alexander J., Professor in the Department of Computer Science, Biology
  • Hogan, Brigid L. M., George Barth Geller Distinguished Professor for Research in Molecular Biology, Cell Biology
  • Krangel, Michael S., George Barth Geller Distinguished Professor of Immunology, Immunology
  • Lew, Daniel Julio, James B. Duke Distinguished Professor of Pharmacology and Cancer Biology, Cell Biology
  • Linardic, Corinne Mary, Associate Professor of Pediatrics, Pharmacology & Cancer Biology
  • McLendon, Roger Edwin, Professor of Pathology, Pathology
  • Milano, Carmelo Alessio, Professor of Surgery, Surgery, Cardiovascular and Thoracic Surgery
  • Sampson, John Howard, Robert H., M.D. and Gloria Wilkins Professor of Neurosurgery, in the School of Medicine, Biomedical Engineering
  • Sunday, Mary Elizabeth Anne, Professor of Pathology, Cell Biology
  • Yan, Hai, Adjunct Professor of Pathology, Pathology