Cell Movement

• 

  Subject Areas on Research

  • 111In oxine labelled mesenchymal stem cell SPECT after intravenous administration in myocardial infarction. 
  • 2-Methoxyestradiol, an endogenous estradiol metabolite, differentially inhibits granulosa and endothelial cell mitosis: a potential follicular antiangiogenic regulator. 
  • 8(S)-hydroxyeicosatetraenoic acid is the lipoxygenase metabolite of arachidonic acid that regulates epithelial cell migration in the rat cornea. 
  • A 3D Poly(ethylene glycol)-based Tumor Angiogenesis Model to Study the Influence of Vascular Cells on Lung Tumor Cell Behavior. 
  • A PK2/Bv8/PROK2 antagonist suppresses tumorigenic processes by inhibiting angiogenesis in glioma and blocking myeloid cell infiltration in pancreatic cancer. 
  • A caudal proliferating growth center contributes to both poles of the forming heart tube. 
  • A cell-specific nuclear receptor is essential for adrenal and gonadal development and sexual differentiation. 
  • A chemotactic factor for mononuclear leukocytes. 
  • A contractile actomyosin network linked to adherens junctions by Canoe/afadin helps drive convergent extension. 
  • A crucial role of L-selectin in C protein-induced experimental polymyositis in mice. 
  • A dual role for ErbB2 signaling in cardiac trabeculation. 
  • A functional role for circulating mouse L-selectin in regulating leukocyte/endothelial cell interactions in vivo. 
  • A high endothelial cell-derived chemokine induces rapid, efficient, and subset-selective arrest of rolling T lymphocytes on a reconstituted endothelial substrate. 
  • A microtubule-destabilizing kinesin motor regulates spindle length and anchoring in oocytes. 
  • A model for migratory B cell oscillations from receptor down-regulation induced by external chemokine fields. 
  • A new activity of doublecortin in recognition of the phospho-FIGQY tyrosine in the cytoplasmic domain of neurofascin. 
  • A novel EGFR isoform confers increased invasiveness to cancer cells. 
  • A novel angiopoietin-derived peptide displays anti-angiogenic activity and inhibits tumour-induced and retinal neovascularization. 
  • A novel chloride channel in Vicia faba guard cell vacuoles activated by the serine/threonine kinase, CDPK. 
  • A novel extracellular Hsp90 mediated co-receptor function for LRP1 regulates EphA2 dependent glioblastoma cell invasion. 
  • A novel low-molecular weight inhibitor of focal adhesion kinase, TAE226, inhibits glioma growth. 
  • A novel missense mutation of Wilms' Tumor 1 causes autosomal dominant FSGS. 
  • A novel splice variant of GLI1 that promotes glioblastoma cell migration and invasion. 
  • A reciprocal tensin-3-cten switch mediates EGF-driven mammary cell migration. 
  • A role for angiotensin II type 1 receptors on bone marrow-derived cells in the pathogenesis of angiotensin II-dependent hypertension. 
  • A small interfering RNA screen for modulators of tumor cell motility identifies MAP4K4 as a promigratory kinase. 
  • A small molecule inhibitor of alpha4 integrin-dependent cell migration. 
  • A spatiotemporally controllable chemical gradient generator via acoustically oscillating sharp-edge structures. 
  • A suppressor/enhancer screen in Drosophila reveals a role for wnt-mediated lipid metabolism in primordial germ cell migration. 
  • A transcriptional repressor of osteopontin expression in the 4T1 murine breast cancer cell line. 
  • A zebrafish model for the Shwachman-Diamond syndrome (SDS). 
  • ABCA transporter gene expression and poor outcome in epithelial ovarian cancer. 
  • ABI2-deficient mice exhibit defective cell migration, aberrant dendritic spine morphogenesis, and deficits in learning and memory. 
  • ADAM10 controls collagen signaling and cell migration on collagen by shedding the ectodomain of discoidin domain receptor 1 (DDR1). 
  • ADF/cofilin promotes invadopodial membrane recycling during cell invasion in vivo. 
  • AJAP1 expression modulates glioma cell motility and correlates with tumor growth and survival. 
  • ALK5 phosphorylation of the endoglin cytoplasmic domain regulates Smad1/5/8 signaling and endothelial cell migration. 
  • AMH induces mesonephric cell migration in XX gonads. 
  • ARHGDIA mutations cause nephrotic syndrome via defective RHO GTPase signaling. 
  • ASTN2 modulates synaptic strength by trafficking and degradation of surface proteins. 
  • Aberrant Otx2 expression enhances migration and induces ectopic proliferation of hindbrain neuronal progenitor cells. 
  • Abi3bp is a multifunctional autocrine/paracrine factor that regulates mesenchymal stem cell biology. 
  • Abl Kinases Regulate HGF/Met Signaling Required for Epithelial Cell Scattering, Tubulogenesis and Motility. 
  • Abl family kinases modulate T cell-mediated inflammation and chemokine-induced migration through the adaptor HEF1 and the GTPase Rap1. 
  • Abl-interactor-1 (Abi1) has a role in cardiovascular and placental development and is a binding partner of the alpha4 integrin. 
  • Accelerated wound healing by injectable microporous gel scaffolds assembled from annealed building blocks. 
  • Accumulation of human immunodeficiency virus-specific cytotoxic T lymphocytes away from the predominant site of virus replication during primary infection. 
  • Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway. 
  • Actin regulation and surface catalysis. 
  • Actin-dependent myoid elongation in teleost rod inner/outer segments occurs in the absence of net actin polymerization. 
  • Activation and signaling of the Abl tyrosine kinase: bidirectional link with phosphoinositide signaling. 
  • Activation of NADPH oxidase 1 increases intracellular calcium and migration of smooth muscle cells. 
  • Activation of Rap1 promotes prostate cancer metastasis. 
  • Activation of protein kinase C inhibits human keratinocyte migration. 
  • Activation of vascular smooth muscle cells by TNF and PDGF: overlapping and complementary signal transduction mechanisms. 
  • Acute podocyte injury is not a stimulus for podocytes to migrate along the glomerular basement membrane in zebrafish larvae. 
  • Adhesion and motility of gliding bacteria on substrata with different surface free energies. 
  • Adhesion molecule cascades direct lymphocyte recirculation and leukocyte migration during inflammation. 
  • Adventitial fibroblasts: backstage journeymen. 
  • Allocation of epiblast cells to germ layer derivatives during mouse gastrulation as studied with a retroviral vector. 
  • Alternative Splicing of EZH2 pre-mRNA by SF3B3 Contributes to the Tumorigenic Potential of Renal Cancer. 
  • An in vitro bioassay for neurite growth using cryostat sections of nervous tissue as a substratum. 
  • An infant with macrocephaly, abnormal neuronal migration and persistent olfactory ventricles. 
  • An inherited abnormality of neutrophil adhesion. Its genetic transmission and its association with a missing protein. 
  • Analogs of tetrahydroisoquinoline natural products that inhibit cell migration and target galectin-3 outside of its carbohydrate-binding site. 
  • Analysis of phosphatases in ER-negative breast cancers identifies DUSP4 as a critical regulator of growth and invasion. 
  • Angiogenic effects of interleukin 8 (CXCL8) in human intestinal microvascular endothelial cells are mediated by CXCR2. 
  • Angiopoietin-1 enhances skeletal muscle regeneration in mice. 
  • Angiostatin binds ATP synthase on the surface of human endothelial cells. 
  • Angiostatin directly inhibits human prostate tumor cell invasion by blocking plasminogen binding to its cellular receptor, CD26. 
  • Angiotensin II mobilizes spleen monocytes to promote the development of abdominal aortic aneurysm in Apoe-/- mice. 
  • Angiotensin II stimulates canonical TGF-β signaling pathway through angiotensin type 1 receptor to induce granulation tissue contraction. 
  • Angiotensin-II mediates nonmuscle myosin II activation and expression and contributes to human keloid disease progression. 
  • Angiotropism of human prostate cancer cells: implications for extravascular migratory metastasis. 
  • Apolipoprotein E COG 133 mimetic peptide improves 5-fluorouracil-induced intestinal mucositis. 
  • Apoptosis induction by p38 MAPK inhibitor in human colon cancer cells. 
  • Apoptotic force and tissue dynamics during Drosophila embryogenesis. 
  • Are cross-bridging structures involved in the bundle formation of intermediate filaments and the decrease in locomotion that accompany cell aging? 
  • Aryl hydrocarbon receptor knock-out exacerbates choroidal neovascularization via multiple pathogenic pathways. 
  • Aspartyl-(asparaginyl)-beta-hydroxylase regulates hepatocellular carcinoma invasiveness. 
  • Assessing activation states in microglia. 
  • Autocrine semaphorin3A stimulates alpha2 beta1 integrin expression/function in breast tumor cells. 
  • Autotaxin, an ectoenzyme that produces lysophosphatidic acid, promotes the entry of lymphocytes into secondary lymphoid organs. 
  • B-LINK: a hemicentin, plakin, and integrin-dependent adhesion system that links tissues by connecting adjacent basement membranes. 
  • B-cell lymphosarcoma cell leukemia: dynamics of surface-membrance immunoglobulin. Value for differentiation from chronic lymphocytic leukemia. 
  • BCL2 inhibits cell adhesion, spreading, and motility by enhancing actin polymerization. 
  • BCL2 interaction with actin in vitro may inhibit cell motility by enhancing actin polymerization. 
  • BDNF-mediated cerebellar granule cell development is impaired in mice null for CaMKK2 or CaMKIV. 
  • Beta-arrestins regulate atherosclerosis and neointimal hyperplasia by controlling smooth muscle cell proliferation and migration. 
  • Beta-catenin and transforming growth factor beta have distinct roles regulating fibroblast cell motility and the induction of collagen lattice contraction. 
  • Bi-directional migration of lens epithelial cells in a physiological electrical field. 
  • Bi-ligand surfaces with oriented and patterned protein for real-time tracking of cell migration. 
  • Binding of activated alpha2-macroglobulin to its cell surface receptor GRP78 in 1-LN prostate cancer cells regulates PAK-2-dependent activation of LIMK. 
  • Biologic functions of the G12 subfamily of heterotrimeric g proteins: growth, migration, and metastasis. 
  • Biological basis of bone formation, remodeling, and repair-part II: extracellular matrix. 
  • Biological function and mechanism of miR-33a in prostate cancer survival and metastasis: via downregulating Engrailed-2. 
  • Bleb Expansion in Migrating Cells Depends on Supply of Membrane from Cell Surface Invaginations. 
  • Bone morphogenetic proteins induce pancreatic cancer cell invasiveness through a Smad1-dependent mechanism that involves matrix metalloproteinase-2. 
  • Bradykinin receptor subtype 1 expression and function in prostate cancer. 
  • Brain cancer stem cells display preferential sensitivity to Akt inhibition. 
  • Brain migration disorder and T-cell activation deficiency associated with abnormal signaling through TCR/CD3 complex and hyperactivity of Fyn tyrosine kinase. 
  • Branching out: origins of the sea urchin larval skeleton in development and evolution. 
  • CD22 expression mediates the regulatory functions of peritoneal B-1a cells during the remission phase of contact hypersensitivity reactions. 
  • CD22 regulates B lymphocyte function in vivo through both ligand-dependent and ligand-independent mechanisms. 
  • CD25+CD4+ regulatory T cell migration requires L-selectin expression: L-selectin transcriptional regulation balances constitutive receptor turnover. 
  • CD44+/CD24- breast cancer cells isolated from MCF-7 cultures exhibit enhanced angiogenic properties. 
  • CD9 plays a role in Schwann cell migration in vitro. 
  • CDK5 regulates cell adhesion and migration in corneal epithelial cells. 
  • CNS myelin wrapping is driven by actin disassembly. 
  • CSPG4 protein as a new target for the antibody-based immunotherapy of triple-negative breast cancer. 
  • CX3CR1-dependent renal macrophage survival promotes Candida control and host survival. 
  • CaM kinase kinase beta-mediated activation of the growth regulatory kinase AMPK is required for androgen-dependent migration of prostate cancer cells. 
  • Calcium influx requirement for human neutrophil chemotaxis: inhibition by lanthanum chloride. 
  • Calcium influx through L-type CaV1.2 Ca2+ channels regulates mandibular development. 
  • Calmodulin in endocrine cells. 
  • Calmodulin-myosin light chain kinase inhibition changes fibroblast-populated collagen lattice contraction, cell migration, focal adhesion formation, and wound contraction. 
  • Cancer-Associated Fibroblasts Induce a Collagen Cross-link Switch in Tumor Stroma. 
  • Capturing change in clonal composition amongst single mouse germinal centers. 
  • Caspase 3 in dying tumor cells mediates post-irradiation angiogenesis. 
  • Caspase-3 regulates the migration, invasion and metastasis of colon cancer cells. 
  • Cdc2 and Mos regulate Emi2 stability to promote the meiosis I-meiosis II transition. 
  • Cell Invasion In Vivo via Rapid Exocytosis of a Transient Lysosome-Derived Membrane Domain. 
  • Cell adhesion in morphogenesis. 
  • Cell adhesion molecules involved in intrathymic T cell development. 
  • Cell adhesion peptides alter smooth muscle cell adhesion, proliferation, migration, and matrix protein synthesis on modified surfaces and in polymer scaffolds. 
  • Cell invasion through basement membrane: the anchor cell breaches the barrier. 
  • Cell lineage conversion in the sea urchin embryo. 
  • Cell mechanics: dissecting the physical responses of cells to force. 
  • Cell migration through defined, synthetic ECM analogs. 
  • Cell motility as a prognostic factor in Stage I nonsmall cell lung carcinoma: the role of gelsolin expression. 
  • Cell signalling by microRNA165/6 directs gene dose-dependent root cell fate. 
  • Cellular and molecular mechanisms of pomegranate juice-induced anti-metastatic effect on prostate cancer cells. 
  • Cellular mechanisms of sex determination in the red-eared slider turtle, Trachemys scripta. 
  • Cellular migration and invasion uncoupled: increased migration is not an inexorable consequence of epithelial-to-mesenchymal transition. 
  • Centrifugal migration of mesenchymal cells in embryonic lung. 
  • Characterization of free-floating spheres from human trabecular meshwork (HTM) cell culture in vitro. 
  • Characterization of the role of cadherin in regulating cell adhesion during sea urchin development. 
  • Chemoattractant receptors on phagocytic cells. 
  • Chemokine mediated control of dendritic cell migration and function. 
  • Chemokines and B-cell homing to follicles. 
  • Chemotaxis-driven assembly of endothelial barrier in a tumor-on-a-chip platform. 
  • Chemotherapy enriches for an invasive triple-negative breast tumor cell subpopulation expressing a precursor form of N-cadherin on the cell surface. 
  • Chimerism in myositis. 
  • Cigarette smoke-induced placental adrenomedullin expression and trophoblast cell invasion. 
  • Class IIb HDAC6 regulates endothelial cell migration and angiogenesis by deacetylation of cortactin. 
  • Clathrin light chains are required for the gyrating-clathrin recycling pathway and thereby promote cell migration. 
  • Combined PI3K/Akt and Smad2 Activation Promotes Corneal Endothelial Cell Proliferation. 
  • Combining necrosis and platelet markers for perfecting myocardial infarction rule out: how close are we? 
  • Comparative analysis of novel and conventional Hsp90 inhibitors on HIF activity and angiogenic potential in clear cell renal cell carcinoma: implications for clinical evaluation. 
  • Comparison of mixed and lamellar coculture spatial arrangements for tissue engineering capillary networks in vitro. 
  • Constitutive protease-activated receptor-2-mediated migration of MDA MB-231 breast cancer cells requires both beta-arrestin-1 and -2. 
  • Constitutively active erythropoietin receptor expression in breast cancer cells promotes cellular proliferation and migration through a MAP-kinase dependent pathway. 
  • Context-specific effects of fibulin-5 (DANCE/EVEC) on cell proliferation, motility, and invasion. Fibulin-5 is induced by transforming growth factor-beta and affects protein kinase cascades. 
  • Contextual tumor suppressor function of T cell death-associated gene 8 (TDAG8) in hematological malignancies. 
  • Contractile proteins in Drosophila development. 
  • Corneal Endothelial Cell Migration and Proliferation Enhanced by Rho Kinase (ROCK) Inhibitors in In Vitro and In Vivo Models. 
  • Cortical inhibition modified by embryonic neural precursors grafted into the postnatal brain. 
  • Counteracting signaling activities in lipid rafts associated with the invasion of lung epithelial cells by Pseudomonas aeruginosa. 
  • Covalently immobilized gradients of bFGF on hydrogel scaffolds for directed cell migration. 
  • Covalently immobilized platelet-derived growth factor-BB promotes angiogenesis in biomimetic poly(ethylene glycol) hydrogels. 
  • Cucurbitacin I inhibits cell motility by indirectly interfering with actin dynamics. 
  • Cutting edge: Role of osteopontin and integrin αv in T cell-mediated anti-inflammatory responses in endotoxemia. 
  • Cutting edge: hierarchy of chemokine receptor and TCR signals regulating T cell migration and proliferation. 
  • Cyclocreatine inhibits stimulated motility in tumor cells possessing creatine kinase. 
  • Cyr61 mediates hepatocyte growth factor-dependent tumor cell growth, migration, and Akt activation. 
  • DISC1-dependent switch from progenitor proliferation to migration in the developing cortex. 
  • Deciphering the mechanisms of tumorigenesis in human pancreatic ductal epithelial cells. 
  • Decreased miRNA-148a is associated with lymph node metastasis and poor clinical outcomes and functions as a suppressor of tumor metastasis in non-small cell lung cancer. 
  • Defective mesonephric cell migration is associated with abnormal testis cord development in C57BL/6J XY(Mus domesticus) mice. 
  • Definition of a functional single nucleotide polymorphism in the cell migration inhibitory gene MIIP that affects the risk of breast cancer. 
  • Delayed wound healing in the absence of intercellular adhesion molecule-1 or L-selectin expression. 
  • Deletion or epigenetic silencing of AJAP1 on 1p36 in glioblastoma. 
  • Delineation of a FOXA1/ERα/AGR2 regulatory loop that is dysregulated in endocrine therapy-resistant breast cancer. 
  • Dendritic development of Purkinje and granule cells in the cerebellar cortex of rats treated postnatally with alpha-difluoromethylornithine. 
  • Deployment of a retinal determination gene network drives directed cell migration in the sea urchin embryo. 
  • Depression of murine macrophage accumulation by low-molecular-weight derived from spontaneous mammary carcinomas. 
  • Desert Hedgehog/Patched 1 signaling specifies fetal Leydig cell fate in testis organogenesis. 
  • Designer monotransregulators provide a basis for a transcriptional therapy for de novo endocrine-resistant breast cancer. 
  • Developmental stage-dependent effects of cardiac fibroblasts on function of stem cell-derived engineered cardiac tissues. 
  • Diacylglycerol kinase zeta regulates actin cytoskeleton reorganization through dissociation of Rac1 from RhoGDI. 
  • Differences in leucocyte-endothelium interactions between normal and adenocarcinoma bearing tissues in response to radiation. 
  • Differential effect of nitric oxide on thrombospondin-1-, PDGF- and fibronectin-induced migration of vascular smooth muscle cells. 
  • Differential effects of platelet-derived growth factor isotypes on human smooth muscle cell proliferation and migration are mediated by distinct signaling pathways. 
  • Differential expression of CD43 (leukosialin, sialophorin) by mononuclear phagocyte populations. 
  • Differential osteopontin expression in phenotypically distinct subclones of murine breast cancer cells mediates metastatic behavior. 
  • Direct involvement of yeast type I myosins in Cdc42-dependent actin polymerization. 
  • Directed cell migration on fibronectin gradients: effect of gradient slope. 
  • Disc1 regulates granule cell migration in the developing hippocampus. 
  • Disruption of testis cords by cyclopamine or forskolin reveals independent cellular pathways in testis organogenesis. 
  • Disruption of wave-associated Rac GTPase-activating protein (Wrp) leads to abnormal adult neural progenitor migration associated with hydrocephalus. 
  • Diversity, topographic differentiation, and positional memory in human fibroblasts. 
  • Down-regulation of platelet-derived growth factor-D inhibits cell growth and angiogenesis through inactivation of Notch-1 and nuclear factor-kappaB signaling. 
  • Drosophila nonmuscle myosin II has multiple essential roles in imaginal disc and egg chamber morphogenesis. 
  • Dual inhibition of αV integrins and Src kinase activity as a combination therapy strategy for colorectal cancer. 
  • Dual labeling of the fibronectin matrix and actin cytoskeleton with green fluorescent protein variants. 
  • Dual labeling of the fibronectin matrix and actin cytoskeleton with green fluorescent protein variants. 
  • Dual roles of tight junction-associated protein, zonula occludens-1, in sphingosine 1-phosphate-mediated endothelial chemotaxis and barrier integrity. 
  • Dynamics of human foveal development after premature birth. 
  • E-selectin can mediate the arrest type of adhesion of colon cancer cells under physiological shear flow. 
  • EGFRvIII-specific chimeric antigen receptor T cells migrate to and kill tumor deposits infiltrating the brain parenchyma in an invasive xenograft model of glioblastoma. 
  • EIF4A3 deficient human iPSCs and mouse models demonstrate neural crest defects that underlie Richieri-Costa-Pereira syndrome. 
  • ELF3 is a repressor of androgen receptor action in prostate cancer cells. 
  • Early differentiation and migration of cranial neural crest in the opossum, Monodelphis domestica. 
  • Early human T cell development: analysis of the human thymus at the time of initial entry of hematopoietic stem cells into the fetal thymic microenvironment. 
  • Ectodomain shedding of TβRIII is required for TβRIII-mediated suppression of TGF-β signaling and breast cancer migration and invasion. 
  • Effect of Mts1 on the structure and activity of nonmuscle myosin II. 
  • Effect of epidermal growth factor on glioma cell growth, migration, and invasion in vitro. 
  • Effect of modulating macrophage phenotype on peripheral nerve repair. 
  • Effect of streptavidin RGD mutant on the adhesion of endothelial cells. 
  • Effect of the conformation and orientation of adsorbed fibronectin on endothelial cell spreading and the strength of adhesion. 
  • Effect of thymectomy on human peripheral blood T cell pools in myasthenia gravis. 
  • Effect of topical azithromycin on corneal innate immune responses. 
  • Effects of Y27632 on keratinocyte procurement and wound healing. 
  • Effects of plasminogen activator inhibitor-1-specific RNA aptamers on cell adhesion, motility, and tube formation. 
  • Effects of the combination of TRC105 and bevacizumab on endothelial cell biology. 
  • Efficient lymphocyte migration across high endothelial venules of mouse Peyer's patches requires overlapping expression of L-selectin and beta7 integrin. 
  • Electric fields and MAP kinase signaling can regulate early wound healing in lens epithelium. 
  • Endogenous RGS proteins attenuate Galpha(i)-mediated lysophosphatidic acid signaling pathways in ovarian cancer cells. 
  • Endogenous presenilin 1 redistributes to the surface of lamellipodia upon adhesion of Jurkat cells to a collagen matrix. 
  • Endoglin Mediates Vascular Maturation by Promoting Vascular Smooth Muscle Cell Migration and Spreading. 
  • Endoglin mediates fibronectin/α5β1 integrin and TGF-β pathway crosstalk in endothelial cells. 
  • Endostatin inhibits the vascular endothelial growth factor-induced mobilization of endothelial progenitor cells. 
  • Endothelial Bmp4 is induced during arterial remodeling: effects on smooth muscle cell migration and proliferation. 
  • Endothelial and steroidogenic cell migration are regulated by WNT4 in the developing mammalian gonad. 
  • Endothelial selectins regulate skin wound healing in cooperation with L-selectin and ICAM-1. 
  • Endotoxin (LPS) stimulates in vitro migration of macrophages from LPS-resistant mice but not from LPS-sensitive mice. 
  • Engineering the cell-material interface for controlling stem cell adhesion, migration, and differentiation. 
  • Engraftment of human synovium into severe combined immune deficient mice. Migration of human peripheral blood T cells to engrafted human synovium and to mouse lymph nodes. 
  • Enhancing the immunostimulatory function of dendritic cells by transfection with mRNA encoding OX40 ligand. 
  • Enrichment of endogenous fractalkine and anti-inflammatory cells via aptamer-functionalized hydrogels. 
  • Ependymal/subependymal zone cells of postnatal and adult songbird brain generate both neurons and nonneuronal siblings in vitro and in vivo. 
  • EphB2 receptor controls proliferation/migration dichotomy of glioblastoma by interacting with focal adhesion kinase. 
  • Epidermal growth factor receptor signaling promotes metastatic prostate cancer through microRNA-96-mediated downregulation of the tumor suppressor ETV6. 
  • Essential role of ICAM-1/CD18 in mediating EPC recruitment, angiogenesis, and repair to the infarcted myocardium. 
  • Estrogen-related receptor alpha is critical for the growth of estrogen receptor-negative breast cancer. 
  • Evidence for multiple roles for grainyhead-like 2 in the establishment and maintenance of human mucociliary airway epithelium.[corrected]. 
  • Ex vivo glycan engineering of CD44 programs human multipotent mesenchymal stromal cell trafficking to bone. 
  • Expression of Neurogenin 1 in mouse embryonic stem cells directs the differentiation of neuronal precursors and identifies unique patterns of down-stream gene expression. 
  • Expression of ezrin correlates with malignant phenotype of lung cancer, and in vitro knockdown of ezrin reverses the aggressive biological behavior of lung cancer cells. 
  • F-actin network formation in tethers and in pseudopods stimulated by chemoattractant. 
  • FGF8 signaling is chemotactic for cardiac neural crest cells. 
  • FIGQY phosphorylation defines discrete populations of L1 cell adhesion molecules at sites of cell-cell contact and in migrating neurons. 
  • FOS-1 promotes basement-membrane removal during anchor-cell invasion in C. elegans. 
  • FRA1 promotes squamous cell carcinoma growth and metastasis through distinct AKT and c-Jun dependent mechanisms. 
  • FZD7 drives in vitro aggressiveness in Stem-A subtype of ovarian cancer via regulation of non-canonical Wnt/PCP pathway. 
  • Factors controlling cardiac neural crest cell migration. 
  • Fast voice-coil scanning optical-resolution photoacoustic microscopy. 
  • Fibrillar systems in cell motility. 
  • Fibronectin isoforms in megakaryocytes. 
  • Fibulin-2 is a driver of malignant progression in lung adenocarcinoma. 
  • Fluorescence-based alternative splicing reporters for the study of epithelial plasticity in vivo. 
  • Four-dimensional analysis of vascularization during primary development of an organ, the gonad. 
  • Fractalkine and CX3CR1 mediate a novel mechanism of leukocyte capture, firm adhesion, and activation under physiologic flow. 
  • Function and evolutionary conservation of distinct epitopes on the leukocyte adhesion molecule-1 (TQ-1, Leu-8) that regulate leukocyte migration. 
  • Function of tau protein in adult newborn neurons. 
  • Functional evaluation of the grafted wall with porcine-derived small intestinal submucosa (SIS) to a stomach defect in rats. 
  • Functional impact of global rare copy number variation in autism spectrum disorders. 
  • Functions of cytoplasmic fibers in intracellular movements in BHK-21 cells. 
  • G protein-coupled receptor kinase 2 activates radixin, regulating membrane protrusion and motility in epithelial cells. 
  • G protein-coupled receptor kinase 2 in multiple sclerosis and experimental autoimmune encephalomyelitis. 
  • G protein-coupled receptor kinase-5 attenuates atherosclerosis by regulating receptor tyrosine kinases and 7-transmembrane receptors. 
  • GABA-induced chemokinesis and NGF-induced chemotaxis of embryonic spinal cord neurons. 
  • GFRα1 released by nerves enhances cancer cell perineural invasion through GDNF-RET signaling. 
  • Galpha12 and Galpha13 negatively regulate the adhesive functions of cadherin. 
  • Genetic Variation in the Platelet Endothelial Aggregation Receptor 1 Gene Results in Endothelial Dysfunction. 
  • Genetic approaches to molecular motors. 
  • Genetic modification of mesenchymal stem cells overexpressing CCR1 increases cell viability, migration, engraftment, and capillary density in the injured myocardium. 
  • Gleevec, an Abl family inhibitor, produces a profound change in cell shape and migration. 
  • Glial localization of antiquitin: implications for pyridoxine-dependent epilepsy. 
  • Global Identification of Small Ubiquitin-related Modifier (SUMO) Substrates Reveals Crosstalk between SUMOylation and Phosphorylation Promotes Cell Migration. 
  • Glutamate acting at NMDA receptors stimulates embryonic cortical neuronal migration. 
  • Gonad morphogenesis in vertebrates: divergent means to a convergent end. 
  • Grab your partner with both hands: cytoskeletal remodeling by Arp2/3 signaling. 
  • Graft-extrinsic cells predominate in vein graft arterialization. 
  • Growth factor receptors, phospholipases, phospholipid kinases and actin reorganization. 
  • HDAC6 deacetylation of tubulin modulates dynamics of cellular adhesions. 
  • HDAC6 modulates cell motility by altering the acetylation level of cortactin. 
  • HIV-1 infection stimulates T cell invasiveness and synthesis of the 92-kDa type IV collagenase. 
  • Habitual physical activity is associated with the maintenance of neutrophil migratory dynamics in healthy older adults. 
  • Hand2 regulates extracellular matrix remodeling essential for gut-looping morphogenesis in zebrafish. 
  • Haptotactic gradients for directed cell migration: stimulation and inhibition using soluble factors. 
  • Hedgehog signaling blockade delays hepatocarcinogenesis induced by hepatitis B virus X protein. 
  • Hedgehog signaling is required for differentiation of endocardial progenitors in zebrafish. 
  • Hedgehog signalling regulates liver sinusoidal endothelial cell capillarisation. 
  • Hemodynamics simulation and identification of susceptible sites of atherosclerotic lesion formation in a model abdominal aorta. 
  • High ratio of synaptic excitation to synaptic inhibition in hilar ectopic granule cells of pilocarpine-treated rats. 
  • High-resolution microscopic methods for the analysis of cellular movements in Drosophila embryos. 
  • Histone deacetylase 6 regulates growth factor-induced actin remodeling and endocytosis. 
  • Hsp90 is an essential regulator of EphA2 receptor stability and signaling: implications for cancer cell migration and metastasis. 
  • Human antigen-specific memory T cells express the homing receptor (LAM-1) necessary for lymphocyte recirculation. 
  • Human lymphocyte motility: normal characteristics and anomalous behavior of chronic lymphocytic leukemia cells. 
  • Human melanoma cell migration along capillary-like structures in vitro: a new dynamic model for studying extravascular migratory metastasis. 
  • Humoral immune responses in L-selectin-deficient mice. 
  • Hypoxia-dependent modification of collagen networks promotes sarcoma metastasis. 
  • ICAM-1-mediated, Src- and Pyk2-dependent vascular endothelial cadherin tyrosine phosphorylation is required for leukocyte transendothelial migration. 
  • IGF1R as a Key Target in High Risk, Metastatic Medulloblastoma. 
  • IL-10 stimulatory effects on human NK cells explored by gene profile analysis. 
  • IL-6 trans-signaling licenses mouse and human tumor microvascular gateways for trafficking of cytotoxic T cells. 
  • IQGAP1, a novel vascular endothelial growth factor receptor binding protein, is involved in reactive oxygen species--dependent endothelial migration and proliferation. 
  • Identification of a Novel Coregulator, SH3YL1, That Interacts With the Androgen Receptor N-Terminus. 
  • Identification of the envelope V3 loop as the primary determinant of cell tropism in HIV-1. 
  • Identifying new small molecule anti-invasive compounds for glioma treatment. 
  • Immigration check for neutrophils in RA lining: laminin alpha5 low expression regions act as exit points. 
  • Immunosurveillance by hematopoietic progenitor cells trafficking through blood, lymph, and peripheral tissues. 
  • Impaired macrophage function underscores susceptibility to Salmonella in mice lacking Irgm1 (LRG-47). 
  • Improved Angiogenesis in Response to Localized Delivery of Macrophage-Recruiting Molecules. 
  • In vitro characteristics of Tenon's fibroblast lines derived from pediatric and adult eyes do not fully explain pediatric glaucoma surgery failure: a preliminary report. 
  • In vivo dendritic cell tracking using fluorescence lifetime imaging and near-infrared-emissive polymersomes. 
  • In vivo imaging of specialized bone marrow endothelial microdomains for tumour engraftment. 
  • In vivo imaging of tumor-propagating cells, regional tumor heterogeneity, and dynamic cell movements in embryonal rhabdomyosarcoma. 
  • Inactivation of the MAL gene in breast cancer is a common event that predicts benefit from adjuvant chemotherapy. 
  • Increased expression of S100A6 is associated with decreased metastasis and inhibition of cell migration and anchorage independent growth in human osteosarcoma. 
  • Increased loss of CCR5+ CD45RA- CD4+ T cells in CD8+ lymphocyte-depleted Simian immunodeficiency virus-infected rhesus monkeys. 
  • Induction of Kruppel-like factor 5 expression by androgens results in increased CXCR4-dependent migration of prostate cancer cells in vitro. 
  • Inflammation does not predispose to bleeding in hemophilia. 
  • Ingression of primary mesenchyme cells of the sea urchin embryo: a precisely timed epithelial mesenchymal transition. 
  • Inhibition of ovarian tumor cell invasiveness by targeting SYK in the tyrosine kinase signaling pathway. 
  • Inhibition of tumor growth by targeting tumor endothelium using a soluble vascular endothelial growth factor receptor. 
  • Inhibition of vascular smooth muscle cell proliferation, migration, and survival by the tumor suppressor protein PTEN. 
  • Inhibitors of prostaglandin synthesis inhibit human prostate tumor cell invasiveness and reduce the release of matrix metalloproteinases. 
  • Injection of immature dendritic cells into adjuvant-treated skin obviates the need for ex vivo maturation. 
  • Insulin-like growth factor-1 is a radial cell-associated neurotrophin that promotes neuronal recruitment from the adult songbird edpendyma/subependyma. 
  • Integrative repair of the meniscus: lessons from in vitro studies. 
  • Integrin acts upstream of netrin signaling to regulate formation of the anchor cell's invasive membrane in C. elegans. 
  • Integrin laminin receptors and breast carcinoma progression. 
  • Integrin-linked kinase regulates p38 MAPK-dependent cell cycle arrest in ureteric bud development. 
  • Integrin-linked kinase: a possible role in scar contracture. 
  • Interferon effects on microfilament organization, cellular fibronectin distribution, and cell motility in human fibroblasts. 
  • Interferon inhibits the redistribution of cell surface components. 
  • Interleukin-1, tumor necrosis factor-alpha, and transforming growth factor-beta 1 and integrative meniscal repair: influences on meniscal cell proliferation and migration. 
  • Interleukin-1beta mediates human airway epithelial cell migration via NF-kappaB. 
  • Intracellular calcium transients are necessary for platelet-derived growth factor but not extracellular matrix protein-induced vascular smooth muscle cell migration. 
  • Intrathecal bone marrow stromal cells inhibit neuropathic pain via TGF-β secretion. 
  • Intrinsic differences in L-selectin expression levels affect T and B lymphocyte subset-specific recirculation pathways. 
  • Invading, Leading and Navigating Cells in Caenorhabditis elegans: Insights into Cell Movement in Vivo. 
  • Invadopodia and basement membrane invasion in vivo. 
  • Investigation of HIFU-induced anti-tumor immunity in a murine tumor model. 
  • Isoprenylcysteine carboxylmethyltransferase function is essential for RAB4A-mediated integrin β3 recycling, cell migration and cancer metastasis. 
  • KASH protein Syne-2/Nesprin-2 and SUN proteins SUN1/2 mediate nuclear migration during mammalian retinal development. 
  • KMT2D maintains neoplastic cell proliferation and global histone H3 lysine 4 monomethylation. 
  • Kalirin promotes neointimal hyperplasia by activating Rac in smooth muscle cells. 
  • Kinesin proteins: a phylum of motors for microtubule-based motility. 
  • Knockdown of ASIC1 and epithelial sodium channel subunits inhibits glioblastoma whole cell current and cell migration. 
  • L-selectin (CD62L) blockade does not impair peritoneal neutrophil emigration or subcutaneous host defense to bacteria in rabbits. 
  • L-selectin and beta7 integrin synergistically mediate lymphocyte migration to mesenteric lymph nodes. 
  • L-selectin and intercellular adhesion molecule 1 mediate lymphocyte migration to the inflamed airway/lung during an allergic inflammatory response in an animal model of asthma. 
  • L-selectin can mediate leukocyte rolling in untreated mesenteric venules in vivo independent of E- or P-selectin. 
  • L-selectin is involved in lymphocyte migration to sites of inflammation in the skin: delayed rejection of allografts in L-selectin-deficient mice. 
  • L-selectin is not required for T cell-mediated autoimmune diabetes. 
  • L-selectin ligands expressed by human leukocytes are HECA-452 antibody-defined carbohydrate epitopes preferentially displayed by P-selectin glycoprotein ligand-1. 
  • L-selectin or ICAM-1 deficiency reduces an immediate-type hypersensitivity response by preventing mast cell recruitment in repeated elicitation of contact hypersensitivity. 
  • L-selectin shedding does not regulate constitutive T cell trafficking but controls the migration pathways of antigen-activated T lymphocytes. 
  • L-selectin shedding does not regulate human neutrophil attachment, rolling, or transmigration across human vascular endothelium in vitro. 
  • L-selectin shedding is activated specifically within transmigrating pseudopods of monocytes to regulate cell polarity in vitro. 
  • LY2109761, a novel transforming growth factor beta receptor type I and type II dual inhibitor, as a therapeutic approach to suppressing pancreatic cancer metastasis. 
  • Laminin mediates tethering and spreading of colon cancer cells in physiological shear flow. 
  • Large scale model studies of apparent viscosity and erythrocyte velocity in capillaries. 
  • Lens fiber cell elongation and differentiation is associated with a robust increase in myosin light chain phosphorylation in the developing mouse. 
  • Leukaemia hijacks a neural mechanism to invade the central nervous system. 
  • Leukemic cells create bone marrow niches that disrupt the behavior of normal hematopoietic progenitor cells. 
  • Leukocyte adhesion molecule-1 (LAM-1, L-selectin) interacts with an inducible endothelial cell ligand to support leukocyte adhesion. 
  • Leukocyte composition of human breast cancer. 
  • Leukocyte entry into sites of inflammation requires overlapping interactions between the L-selectin and ICAM-1 pathways. 
  • Leukocyte interactions with vascular endothelium. New insights into selectin-mediated attachment and rolling. 
  • Leukocyte migration is regulated by L-selectin endoproteolytic release. 
  • Leukocyte rolling velocities and migration are optimized by cooperative L-selectin and intercellular adhesion molecule-1 functions. 
  • Leukotriene C4 induces migration of human monocyte-derived dendritic cells without loss of immunostimulatory function. 
  • Ligation of prostate cancer cell surface GRP78 activates a proproliferative and antiapoptotic feedback loop: a role for secreted prostate-specific antigen. 
  • Lipid binding to the tail domain of vinculin: specificity and the role of the N and C termini. 
  • Localization of heparin cofactor II in injured human skin: a potential role in wound healing. 
  • Localization of mesenchymal stem cells grafted with a hyaluronan-based scaffold in the infarcted heart. 
  • Loss of betaglycan expression in ovarian cancer: role in motility and invasion. 
  • Loss of pericyte smoothened activity in mice with genetic deficiency of leptin. 
  • Loss of phosphatase and tensin homologue increases transforming growth factor beta-mediated invasion with enhanced SMAD3 transcriptional activity. 
  • Loss of type III transforming growth factor beta receptor expression increases motility and invasiveness associated with epithelial to mesenchymal transition during pancreatic cancer progression. 
  • Lymphocyte accumulation in the spleen of retinoic acid receptor-related orphan receptor gamma-deficient mice. 
  • Lymphocyte homing and leukocyte rolling and migration are impaired in L-selectin-deficient mice. 
  • Lymphotoxin alpha/beta and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleen. 
  • Lyphocyte migration in L-selectin-deficient mice. Altered subset migration and aging of the immune system. 
  • Lysyl oxidase is essential for hypoxia-induced metastasis. 
  • MIG-10 (Lamellipodin) stabilizes invading cell adhesion to basement membrane and is a negative transcriptional target of EGL-43 in C. elegans. 
  • MIG-10 (lamellipodin) has netrin-independent functions and is a FOS-1A transcriptional target during anchor cell invasion in C. elegans. 
  • MRCK-1 Drives Apical Constriction in C. elegans by Linking Developmental Patterning to Force Generation. 
  • Macrophage activation by gastric fluid suggests MMP involvement in aspiration-induced lung disease. 
  • Macrophage migration into hepatic xenografts in the hamster-to-rat combination. 
  • Macrophage-stimulating protein and its receptor in non-small-cell lung tumors: induction of receptor tyrosine phosphorylation and cell migration. 
  • Macrophages and cardiac fibroblasts are the main producers of eotaxins and regulate eosinophil trafficking to the heart. 
  • Macrophages and infertility: oviductal macrophages as potential mediators of infertility. 
  • Male-specific cell migration into the developing gonad. 
  • Manipulating JNK signaling with (--)-zuonin A. 
  • Mast cell-orchestrated immunity to pathogens. 
  • Matrix metalloproteinase activity modulates tumor size, cell motility, and cell invasiveness in murine aggressive fibromatosis. 
  • Measurement of cell migration on surface-bound fibronectin gradients. 
  • Measurement of erythrocyte velocity by use of a periodic differential detector. 
  • Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics 
  • Mechanical anchoring strength of L-selectin, beta2 integrins, and CD45 to neutrophil cytoskeleton and membrane. 
  • Mechanical feedback through E-cadherin promotes direction sensing during collective cell migration. 
  • Mechanical stiffness grades metastatic potential in patient tumor cells and in cancer cell lines. 
  • Mechanisms of cellular protrusions branch out. 
  • Mechanisms of excitation and adaptation in Dictyostelium. 
  • Medusa cells: the morphology and cytochemistry of common amoeboid variants of eosinophils. 
  • Meiotic germ cells antagonize mesonephric cell migration and testis cord formation in mouse gonads. 
  • Merosin promotes neurite growth and Schwann cell migration in vitro and nerve regeneration in vivo: evidence using an antibody to merosin, ARM-1. 
  • Mesenchymal stem cells use integrin beta1 not CXC chemokine receptor 4 for myocardial migration and engraftment. 
  • Mesonephric cell migration induces testis cord formation and Sertoli cell differentiation in the mammalian gonad. 
  • Metastable tolerance to rhesus monkey renal transplants is correlated with allograft TGF-beta 1+CD4+ T regulatory cell infiltrates. 
  • MiR-148a functions to suppress metastasis and serves as a prognostic indicator in triple-negative breast cancer. 
  • Mice lacking expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localization. 
  • Mice that overexpress CC chemokine ligand 2 in their lungs show increased protective immunity to infection with Mycobacterium bovis bacille Calmette-Guérin. 
  • Micro-RNA-181a regulates osteopontin-dependent metastatic function in hepatocellular cancer cell lines. 
  • Micro-scale and meso-scale architectural cues cooperate and compete to direct aligned tissue formation. 
  • MicroRNA-16 suppresses metastasis in an orthotopic, but not autochthonous, mouse model of soft tissue sarcoma. 
  • MicroRNA-182 drives metastasis of primary sarcomas by targeting multiple genes. 
  • MicroRNA-31 controls G protein alpha-13 (GNA13) expression and cell invasion in breast cancer cells. 
  • MicroRNAs in skin tissue engineering. 
  • Microchimerism in children with rheumatic disorders: what does it mean? 
  • Microtubule disruption leads to cellular contraction in human trabecular meshwork cells. 
  • Migrating keratinocytes express urokinase-type plasminogen activator. 
  • Migration of human dendritic cells after injection in patients with metastatic malignancies. 
  • Migration of mesonephric cells into the mammalian gonad depends on Sry. 
  • Mitochondrial Superoxide Dismutase Has a Protumorigenic Role in Ovarian Clear Cell Carcinoma. 
  • Mitogen-activated protein kinase phosphatase-1 promotes neovascularization and angiogenic gene expression. 
  • Mitogenesis, cell migration, and loss of focal adhesions induced by tenascin-C interacting with its cell surface receptor, annexin II. 
  • Molecular editing of cellular responses by the high-affinity receptor for IgE. 
  • Molecular genetic dissection of myosin heavy chain function. 
  • Molecular interactions of B-CAM (basal-cell adhesion molecule) and laminin in epithelial skin cancer. 
  • Monoclonal antibodies against the CD44 [In(Lu)-related p80], and Pgp-1 antigens in man recognize the Hermes class of lymphocyte homing receptors. 
  • Monoclonal antibody interaction with the third immunoglobulin-like domain of N-CAM is sufficient to cause cell migration. 
  • Multi-gene targeted antiangiogenic therapies for experimental corneal neovascularization. 
  • Multiple tissue-specific requirements for the BMP antagonist Noggin in development of the mammalian craniofacial skeleton. 
  • Mutation location on the RAS oncogene affects pathologic features and survival after resection of colorectal liver metastases. 
  • Mutations in the gene that encodes the F-actin binding protein anillin cause FSGS. 
  • Mylar and Teflon-AF as cell culture substrates for studying endothelial cell adhesion. 
  • Myocardial volume and organization are changed by failure of addition of secondary heart field myocardium to the cardiac outflow tract. 
  • N-myc alters the fate of preneoplastic cells in a mouse model of medulloblastoma. 
  • NADPH oxidase 4: walking the walk with Poldip2. 
  • Natural killer cell responses to viral infection. 
  • Nerve growth factor and its low-affinity receptor promote Schwann cell migration. 
  • Neural crest and cardiovascular development: a 20-year perspective. 
  • Neuronal migration disorders: positron emission tomography correlations. 
  • Neutrophil margination, sequestration, and emigration in the lungs of L-selectin-deficient mice. 
  • Neutrophil migration is defective during recombinant human granulocyte-macrophage colony-stimulating factor infusion after autologous bone marrow transplantation in humans. 
  • New insights from a high-resolution look at gastrulation in the sea urchin, Lytechinus variegatus. 
  • New murine cell line derived from a spontaneous lung tumor induces paraneoplastic syndromes. 
  • Nitric oxide regulates matrix metalloproteinase-9 activity by guanylyl-cyclase-dependent and -independent pathways. 
  • Nitric oxide-dependent osteopontin expression induces metastatic behavior in HepG2 cells. 
  • Nordihydroguaiaretic acid inhibits insulin-like growth factor signaling, growth, and survival in human neuroblastoma cells. 
  • Notochord vacuoles are lysosome-related organelles that function in axis and spine morphogenesis. 
  • Novel immunoregulatory B cell pathways revealed by lpr-+ mixed chimeras. 
  • Novel small leucine-rich repeat protein podocan is a negative regulator of migration and proliferation of smooth muscle cells, modulates neointima formation, and is expressed in human atheroma. 
  • Nox1 transactivation of epidermal growth factor receptor promotes N-cadherin shedding and smooth muscle cell migration. 
  • Oesophageal and sternohyal muscle fibres are novel Pax3-dependent migratory somite derivatives essential for ingestion. 
  • Optimal selectin-mediated rolling of leukocytes during inflammation in vivo requires intercellular adhesion molecule-1 expression. 
  • Osteopontin has a protective role in prostate tumor development in mice. 
  • Osteopontin inhibits expression of cytochrome c oxidase in RAW 264.7 murine macrophages. 
  • Osteopontin silencing by small interfering RNA suppresses in vitro and in vivo CT26 murine colon adenocarcinoma metastasis. 
  • Osteopontin-dependent CD44v6 expression and cell adhesion in HepG2 cells. 
  • Overcoming Chronic Rejection-Can it B? 
  • Overexpression of integrin alphav promotes human osteosarcoma cell populated collagen lattice contraction and cell migration. 
  • Overexpression of soluble fas attenuates transplant arteriosclerosis in rat aortic allografts. 
  • Overlapping roles for L-selectin and P-selectin in antigen-induced immune responses in the microvasculature. 
  • PECAM-1 dampens cytokine levels during LPS-induced endotoxemia by regulating leukocyte trafficking. 
  • PECAM-1: conflicts of interest in inflammation. 
  • PPARβ/δ selectively regulates phenotypic features of age-related macular degeneration. 
  • PREX1 integrates G protein-coupled receptor and phosphoinositide 3-kinase signaling to promote glioblastoma invasion. 
  • PTEN as an effector in the signaling of antimigratory G protein-coupled receptor. 
  • PTEN modulates vascular endothelial growth factor-mediated signaling and angiogenic effects. 
  • Palladin is an actin cross-linking protein that uses immunoglobulin-like domains to bind filamentous actin. 
  • Paracrine signaling through the JAK/STAT pathway activates invasive behavior of ovarian epithelial cells in Drosophila. 
  • Pathogenesis of NOD diabetes is initiated by reactivity to the insulin B chain 9-23 epitope and involves functional epitope spreading. 
  • Pathogenesis of pneumococcal pneumonia in cyclophosphamide-induced leukopenia in mice. 
  • Peptide interfacial biomaterials improve endothelial cell adhesion and spreading on synthetic polyglycolic acid materials. 
  • Performance comparison between the high-speed Yokogawa spinning disc confocal system and single-point scanning confocal systems. 
  • Pericyte-like location of GFP-tagged melanoma cells: ex vivo and in vivo studies of extravascular migratory metastasis. 
  • Pericytic-like angiotropism of glioma and melanoma cells. 
  • Peritubular myoid cells are not the migrating population required for testis cord formation in the XY gonad. 
  • Phorbol myristate acetate stimulates pinocytosis and membrane spreading in mouse peritoneal macrophages. 
  • Phosphodiesterase 5 inhibition ameliorates angiontensin II-induced podocyte dysmotility via the protein kinase G-mediated downregulation of TRPC6 activity. 
  • Phosphorylation of Nox1 regulates association with NoxA1 activation domain. 
  • Phosphorylation of adducin by Rho-kinase plays a crucial role in cell motility. 
  • Phototaxis by the dinoflagellate Gymnodinium splendens Lebour. 
  • Physiological implications of the presence, distribution, and regulation of calmodulin in eukaryotic cells. 
  • Pigmented Lesions of the Nervous System and the Neural Crest: Lessons From Embryology. 
  • Planar cell polarity acts through septins to control collective cell movement and ciliogenesis. 
  • Pleiotrophin regulates the ductular reaction by controlling the migration of cells in liver progenitor niches. 
  • Plexin-B2 negatively regulates macrophage motility, Rac, and Cdc42 activation. 
  • Point sources of Schwann cells result in growth into a nerve entubulation repair site in the absence of axons: effects of freeze-thawing. 
  • Postreceptor signal transduction by cyclic adenosine monophosphate and the Ca2+-calmodulin complex. 
  • Preclinical activity profile and therapeutic efficacy of the HSP90 inhibitor ganetespib in triple-negative breast cancer. 
  • Prenatal nicotine exposure evokes alterations of cell structure in hippocampus and somatosensory cortex. 
  • Prenylated c17orf37 induces filopodia formation to promote cell migration and metastasis. 
  • Preventing stem cell incorporation into choroidal neovascularization by targeting homing and attachment factors. 
  • Prevention and treatment of diabetes with resveratrol in a non-obese mouse model of type 1 diabetes. 
  • Production and characterization of an antibody to myosin light chain kinase and intracellular localization of the enzyme. 
  • Production of a retroviral P15E-related chemotaxis inhibitor by IL-1-treated endothelial cells. A possible negative feedback in the regulation of the vascular response to monokines. 
  • Prognostic significance of MCM2, Ki-67 and gelsolin in non-small cell lung cancer. 
  • Prolonged beta-catenin stabilization and tcf-dependent transcriptional activation in hyperplastic cutaneous wounds. 
  • Protective astrogenesis from the SVZ niche after injury is controlled by Notch modulator Thbs4. 
  • Proteoglycan signaling co-receptors: roles in cell adhesion, migration and invasion. 
  • Quantification of cell edge velocities and traction forces reveals distinct motility modules during cell spreading. 
  • Quantitative analysis of the spatiotemporal dynamics of a synthetic predator-prey ecosystem. 
  • Questionable relevance of gamma delta T lymphocytes in renal cell carcinoma. 
  • Quinocarmycin analog DX-52-1 inhibits cell migration and targets radixin, disrupting interactions of radixin with actin and CD44. 
  • RHO methylation matters: a role for isoprenylcysteine carboxylmethyltransferase in cell migration and adhesion. 
  • Rac1 GTPase-deficient mouse lens exhibits defects in shape, suture formation, fiber cell migration and survival. 
  • Radial migration: Retinal neurons hold on for the ride. 
  • Rap1 GTPase inhibits leukocyte transmigration by promoting endothelial barrier function. 
  • Rapamycin inhibits fibronectin-induced migration of the human arterial smooth muscle line (E47) through the mammalian target of rapamycin. 
  • Rapid fusion between mesenchymal stem cells and cardiomyocytes yields electrically active, non-contractile hybrid cells. 
  • Re-orientation and faster, directed migration of lens epithelial cells in a physiological electric field. 
  • Reactive oxygen species in vascular endothelial cell motility. Roles of NAD(P)H oxidase and Rac1. 
  • Redirecting migration of T cells to chemokine secreted from tumors by genetic modification with CXCR2. 
  • Regenerative scaffold electrodes for peripheral nerve interfacing. 
  • Regulation of corneal inflammation by neutrophil-dependent cleavage of keratan sulfate proteoglycans as a model for breakdown of the chemokine gradient. 
  • Regulation of cyclin D1/Cdk4 complexes by calcium/calmodulin-dependent protein kinase I. 
  • Regulation of leukocyte migration by activation of the leukocyte adhesion molecule-1 (LAM-1) selectin. 
  • Regulation of leukocyte rolling and adhesion to high endothelial venules through the cytoplasmic domain of L-selectin. 
  • Regulation of macrophage motility by Irgm1. 
  • Regulation of the platelet-derived growth factor receptor-beta by G protein-coupled receptor kinase-5 in vascular smooth muscle cells involves the phosphatase Shp2. 
  • Regulation of vascular endothelial growth factor receptor-1 expression by specificity proteins 1, 3, and 4 in pancreatic cancer cells. 
  • Requirement of HDAC6 for transforming growth factor-beta1-induced epithelial-mesenchymal transition. 
  • Requirements for T lymphocyte migration in explanted lymph nodes. 
  • Resistance to tyrosine kinase inhibition by mutant epidermal growth factor receptor variant III contributes to the neoplastic phenotype of glioblastoma multiforme. 
  • Resolving postoperative neuroinflammation and cognitive decline. 
  • Rho GDP dissociation inhibitor-mediated disruption of Rho GTPase activity impairs lens fiber cell migration, elongation and survival. 
  • Rho kinase differentially regulates phosphorylation of nonmuscle myosin II isoforms A and B during cell rounding and migration. 
  • RhoG regulates endothelial apical cup assembly downstream from ICAM1 engagement and is involved in leukocyte trans-endothelial migration. 
  • Role of CCR7 in facilitating direct allosensitization and regulatory T-cell function in high-risk corneal transplantation. 
  • Role of G12 proteins in oncogenesis and metastasis. 
  • Role of T cell recruitment and chemokine-regulated intra-graft T cell motility patterns in corneal allograft rejection. 
  • Role of TGF-β receptor III localization in polarity and breast cancer progression. 
  • Role of adhesion molecules in the pathogenesis of rheumatoid arthritis. 
  • Role of decreased levels of lipid phosphate phosphatase-1 in accumulation of lysophosphatidic acid in ovarian cancer. 
  • Role of fibronectin in topographical guidance of neurite extension on electrospun fibers. 
  • Role of isoprenylcysteine carboxylmethyltransferase-catalyzed methylation in Rho function and migration. 
  • Role of natural killer cell function in dendritic cell-based vaccines. 
  • Role of repulsive factors in vascularization dynamics. 
  • Role of transforming growth factor-beta in hematologic malignancies. 
  • Role of transmethylation reactions in cellular motility and phagocytosis. 
  • S1P-Dependent trafficking of intracellular yersinia pestis through lymph nodes establishes Buboes and systemic infection. 
  • SB-431542, a small molecule transforming growth factor-beta-receptor antagonist, inhibits human glioma cell line proliferation and motility. 
  • SCAR, a WASP-related protein, isolated as a suppressor of receptor defects in late Dictyostelium development. 
  • SECTM1 produced by tumor cells attracts human monocytes via CD7-mediated activation of the PI3K pathway. 
  • SOCS3 inhibiting migration of A549 cells correlates with PYK2 signaling in vitro. 
  • STAT3-mediated coincidence detection regulates noncanonical immediate early gene induction. 
  • STRIP1, a core component of STRIPAK complexes, is essential for normal mesoderm migration in the mouse embryo. 
  • SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice. 
  • Secondary lymphoid-tissue chemokine (SLC) stimulates integrin alpha 4 beta 7-mediated adhesion of lymphocytes to mucosal addressin cell adhesion molecule-1 (MAdCAM-1) under flow. 
  • Secreted Hsp90 is a novel regulator of the epithelial to mesenchymal transition (EMT) in prostate cancer. 
  • Selective modification of antigen-specific T cells by RNA electroporation. 
  • Senescent phenotypes and telomere lengths of peripheral blood T-cells mobilized by acute exercise in humans. 
  • Sertoli cells of the mouse testis originate from the coelomic epithelium. 
  • Signal transduction in cells following binding of chemoattractants to membrane receptors. 
  • Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway. 
  • Significance of complement to the mechanism of action of endotoxin. 
  • Site of substrate stimulation of jejunal sucrase in the rat. 
  • Smad3 signaling critically regulates fibroblast phenotype and function in healing myocardial infarction. 
  • Smooth Muscle Cell-targeted RNA Aptamer Inhibits Neointimal Formation. 
  • Smooth Muscle Cell-targeted RNA Aptamer Inhibits Neointimal Formation. 
  • Smooth muscle cell growth in photopolymerized hydrogels with cell adhesive and proteolytically degradable domains: synthetic ECM analogs for tissue engineering. 
  • Smooth muscle cell migration and proliferation are mediated by distinct phases of activation of the intracellular messenger mitogen-activated protein kinase. 
  • Smooth muscle cell rigidity and extracellular matrix organization influence endothelial cell spreading and adhesion formation in coculture. 
  • Snail promotes resistance to enzalutamide through regulation of androgen receptor activity in prostate cancer. 
  • Sonic hedgehog from pharyngeal arch 1 epithelium is necessary for early mandibular arch cell survival and later cartilage condensation differentiation. 
  • Sorafenib suppresses postsurgical recurrence and metastasis of hepatocellular carcinoma in an orthotopic mouse model. 
  • Spectral-domain phase microscopy. 
  • Sry and the testis: molecular pathways of organogenesis. 
  • Static and dynamic lengths of neutrophil microvilli. 
  • Sub-circuits of a gene regulatory network control a developmental epithelial-mesenchymal transition. 
  • Substance P primes human neutrophil activation: a mechanism for neurological regulation of inflammation. 
  • Superoxide-mediated actin response in post-hypoxic endothelial cells. 
  • Survival of allografted pancreatic islets in the subretinal space in rats. 
  • Survival of subretinal pancreatic islet cell allografts and apoptosis in infiltrating lymphocytes in rats. 
  • Synergistic induction of mitogen-activated protein kinase phosphatase-1 by thrombin and epidermal growth factor requires vascular endothelial growth factor receptor-2. 
  • TGF-β regulates LARG and GEF-H1 during EMT to affect stiffening response to force and cell invasion. 
  • TGF-β-Induced Transcription Sustains Amoeboid Melanoma Migration and Dissemination. 
  • TGFbeta-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory TGFbeta switch. 
  • TGFβ1 Polymorphisms Predict Distant Metastasis-Free Survival in Patients with Inoperable Non-Small-Cell Lung Cancer after Definitive Radiotherapy. 
  • TLR9 agonist acts by different mechanisms synergizing with bevacizumab in sensitive and cetuximab-resistant colon cancer xenografts. 
  • TNXB mutations can cause vesicoureteral reflux. 
  • Targeting GLI1 expression in human inflammatory breast cancer cells enhances apoptosis and attenuates migration. 
  • Targeting Id1 and Id3 inhibits peritoneal metastasis of gastric cancer. 
  • Targeting SET/I(2)PP2A oncoprotein functions as a multi-pathway strategy for cancer therapy. 
  • Targeting UDP-α-D-glucose 6-dehydrogenase inhibits glioblastoma growth and migration. 
  • Targeting inhibitors of the tumor suppressor PP2A for the treatment of pancreatic cancer. 
  • Targeting of integrin beta1 and kinesin 2alpha by microRNA 183. 
  • Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis. 
  • Temporal and molecular separation of the kit receptor tyrosine kinase's roles in zebrafish melanocyte migration and survival. 
  • Tenascin supports lymphocyte rolling. 
  • Tension Creates an Endoreplication Wavefront that Leads Regeneration of Epicardial Tissue. 
  • Tetanus toxoid and CCL3 improve dendritic cell vaccines in mice and glioblastoma patients. 
  • Tetraspanin 3 Is Required for the Development and Propagation of Acute Myelogenous Leukemia. 
  • The Abl family kinases: mechanisms of regulation and signaling. 
  • The Actin-Binding Protein Drebrin Inhibits Neointimal Hyperplasia. 
  • The CC chemokine thymus-derived chemotactic agent 4 (TCA-4, secondary lymphoid tissue chemokine, 6Ckine, exodus-2) triggers lymphocyte function-associated antigen 1-mediated arrest of rolling T lymphocytes in peripheral lymph node high endothelial venules. 
  • The CXC chemokine cCAF stimulates precocious deposition of ECM molecules by wound fibroblasts, accelerating development of granulation tissue. 
  • The DNA damage- and transcription-associated protein paxip1 controls thymocyte development and emigration. 
  • The E3-ligase E6AP Represses Breast Cancer Metastasis via Regulation of ECT2-Rho Signaling. 
  • The NADPH oxidase NOX4 represses epithelial to amoeboid transition and efficient tumour dissemination. 
  • The PapG tip adhesin of P fimbriae protects Escherichia coli from neutrophil bactericidal activity. 
  • The SHREW1 gene, frequently deleted in oligodendrogliomas, functions to inhibit cell adhesion and migration. 
  • The abnormal surface characteristics of the red blood cell membrane in congenital dyserythropoietic anaemia type II (HEMPAS). 
  • The actin membrane skeleton in Drosophila development. 
  • The activated transforming growth factor-beta signaling pathway in peritoneal metastases is a potential therapeutic target in ovarian cancer. 
  • The adherens junction-associated protein 1 is a negative transcriptional regulator of MAGEA2, which potentiates temozolomide-induced apoptosis in GBM. 
  • The balance of cell surface and soluble type III TGF-β receptor regulates BMP signaling in normal and cancerous mammary epithelial cells. 
  • The battle of the sexes. 
  • The biocompatibility of titanium cardiovascular devices seeded with autologous blood-derived endothelial progenitor cells: EPC-seeded antithrombotic Ti implants. 
  • The centrosome in human genetic disease. 
  • The combination of novel low molecular weight inhibitors of RAF (LBT613) and target of rapamycin (RAD001) decreases glioma proliferation and invasion. 
  • The cutaneous reverse Arthus reaction requires intercellular adhesion molecule 1 and L-selectin expression. 
  • The cytolytic molecules Fas ligand and TRAIL are required for murine thymic graft-versus-host disease. 
  • The differential role of L-selectin and ICAM-1 in Th1-type and Th2-type contact hypersensitivity. 
  • The effect of alpha-v integrin inhibition on the malignant characteristics of medulloblastoma. 
  • The effect of cigarette smoke extract on trophoblast cell viability and migration: the role of adrenomedullin. 
  • The effect of total-body irradiation on corneal neovascularization in the Fischer 344 rat after chemical cauterization. 
  • The effect of vascular endothelial growth factor (VEGF) presentation within fibrin matrices on endothelial cell branching. 
  • The effects of nicotine on vascular smooth muscle cell chemotaxis induced by thrombospondin-1 and fibronectin. 
  • The emerging concept of vascular remodeling. 
  • The extracellular matrix protein mindin regulates trafficking of murine eosinophils into the airspace. 
  • The homeodomain protein HOXB13 regulates the cellular response to androgens. 
  • The inflammatory response to cardiopulmonary bypass. 
  • The integrin-linked kinase regulates cell morphology and motility in a rho-associated kinase-dependent manner. 
  • The interaction of endoglin with beta-arrestin2 regulates transforming growth factor-beta-mediated ERK activation and migration in endothelial cells. 
  • The metastatic odyssey: the integrin connection. 
  • The modulation of MSC integrin expression by RGD presentation. 
  • The netrin receptor DCC focuses invadopodia-driven basement membrane transmigration in vivo. 
  • The nuclear receptor steroidogenic factor 1 is essential for the formation of the ventromedial hypothalamic nucleus. 
  • The nucleic acid scavenger polyamidoamine third-generation dendrimer inhibits fibroblast activation and granulation tissue contraction. 
  • The phosphorylation of vascular endothelial growth factor receptor-2 (VEGFR-2) by engineered surfaces with electrostatically or covalently immobilized VEGF. 
  • The role of integrins in saphenous vein vascular smooth muscle cell migration. 
  • The role of osteopontin and osteopontin aptamer (OPN-R3) in fibroblast activity. 
  • The role of thin filopodia in motility and morphogenesis. 
  • The roles of L-selectin, beta 7 integrins, and P-selectin in leukocyte rolling and adhesion in high endothelial venules of Peyer's patches. 
  • The selectins: vascular adhesion molecules. 
  • The spreading, migration and proliferation of mouse mesenchymal stem cells cultured inside hyaluronic acid hydrogels. 
  • The type III TGF-beta receptor regulates epithelial and cancer cell migration through beta-arrestin2-mediated activation of Cdc42. 
  • The type III TGF-beta receptor suppresses breast cancer progression through GIPC-mediated inhibition of TGF-beta signaling. 
  • The type III TGFbeta receptor regulates directional migration: new tricks for an old dog. 
  • The type III transforming growth factor-beta receptor as a novel tumor suppressor gene in prostate cancer. 
  • The type III transforming growth factor-beta receptor negatively regulates nuclear factor kappa B signaling through its interaction with beta-arrestin2. 
  • The type III transforming growth factor-β receptor inhibits proliferation, migration, and adhesion in human myeloma cells. 
  • The winged helix transcription factor MFH1 is required for proliferation and patterning of paraxial mesoderm in the mouse embryo. 
  • Therapeutic efficacy of endostatin exhibits a biphasic dose-response curve. 
  • Three-dimensional culture systems in cancer research: Focus on tumor spheroid model. 
  • Three-dimensional micropatterning of bioactive hydrogels via two-photon laser scanning photolithography for guided 3D cell migration. 
  • Thrombin-cleaved COOH(-) terminal osteopontin peptide binds with cyclophilin C to CD147 in murine breast cancer cells. 
  • Tissue-specific migration pathways by phenotypically distinct subpopulations of memory T cells. 
  • Transduction of receptor signals by beta-arrestins. 
  • Trophic effects of androgen: development and hormonal regulation of neuron number in a sexually dimorphic vocal motor nucleus. 
  • Tumor Endothelial Cells with Distinct Patterns of TGFβ-Driven Endothelial-to-Mesenchymal Transition. 
  • Tumor microenvironment tenascin-C promotes glioblastoma invasion and negatively regulates tumor proliferation. 
  • Two distinct origins for Leydig cell progenitors in the fetal testis. 
  • Type III TGF-β receptor enhances colon cancer cell migration and anchorage-independent growth. 
  • Ubiquitin-Related Roles of β-Arrestins in Endocytic Trafficking and Signal Transduction. 
  • Unphosphorylated gelsolin is localized in regions of cell-substratum contact or attachment in Rous sarcoma virus-transformed rat cells. 
  • Up-regulating sphingosine 1-phosphate receptor-2 signaling impairs chemotactic, wound-healing, and morphogenetic responses in senescent endothelial cells. 
  • Upregulation of VEGF-A and CD24 gene expression by the tGLI1 transcription factor contributes to the aggressive behavior of breast cancer cells. 
  • Using avidin-mediated binding to enhance initial endothelial cell attachment and spreading. 
  • Val-ala-pro-gly, an elastin-derived non-integrin ligand: smooth muscle cell adhesion and specificity. 
  • Vascular endothelial growth factor promotes breast carcinoma invasion in an autocrine manner by regulating the chemokine receptor CXCR4. 
  • Vascular smooth muscle cell migration induced by domains of thrombospondin-1 is differentially regulated. 
  • Vascular-mesenchymal cross-talk through Vegf and Pdgf drives organ patterning. 
  • Vertebrate kidney tubules elongate using a planar cell polarity-dependent, rosette-based mechanism of convergent extension. 
  • Visualization and characterization of inflammatory cell recruitment and migration through the corneal stroma in endotoxin-induced keratitis. 
  • WNT11 expression is induced by estrogen-related receptor alpha and beta-catenin and acts in an autocrine manner to increase cancer cell migration. 
  • Whole-exome sequencing studies of parathyroid carcinomas reveal novel PRUNE2 mutations, distinctive mutational spectra related to APOBEC-catalyzed DNA mutagenesis and mutational enrichment in kinases associated with cell migration and invasion. 
  • XIAP Regulation by MNK Links MAPK and NFκB Signaling to Determine an Aggressive Breast Cancer Phenotype. 
  • Yin yang 1 modulates taxane response in epithelial ovarian cancer. 
  • ZD6474, a novel tyrosine kinase inhibitor of vascular endothelial growth factor receptor and epidermal growth factor receptor, inhibits tumor growth of multiple nervous system tumors. 
  • ZNHIT3 is defective in PEHO syndrome, a severe encephalopathy with cerebellar granule neuron loss. 
  • [Expression of presenilin 1 on the cell surface in motile polarized cells]. 
  • alpha-Crystallin localizes to the leading edges of migrating lens epithelial cells. 
  • beta-Catenin stabilization dysregulates mesenchymal cell proliferation, motility, and invasiveness and causes aggressive fibromatosis and hyperplastic cutaneous wounds. 
  • c-Jun Contributes to Transcriptional Control of GNA12 Expression in Prostate Cancer Cells. 
  • miR-126 and miR-126* repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis. 
  • miR-1269 promotes metastasis and forms a positive feedback loop with TGF-β. 
  • siRNA inhibition of aspartyl-asparaginyl β-hydroxylase expression impairs cell motility, Notch signaling, and fetal growth. 
  • α4β7 Integrin is essential for contact hypersensitivity by regulating migration of T cells to skin. 
  • αPIX RhoGEF supports positive selection by restraining migration and promoting arrest of thymocytes. 
  • β-Arrestin mediates oxytocin receptor signaling, which regulates uterine contractility and cellular migration. 
  • β-Catenin-regulated myeloid cell adhesion and migration determine wound healing. 
  • β-arrestin deficiency protects against pulmonary fibrosis in mice and prevents fibroblast invasion of extracellular matrix. 
• 

  Keywords of People

  • Abbruzzese, James, D. C. I. Professor of Medical Oncology, Medicine, Medical Oncology
  • Allori, Alexander C, Assistant Professor of Surgery, Surgery, Plastic, Maxillofacial, and Oral Surgery
  • Bennett, Vann, George B. Geller Professor for Research in Molecular Biology in the School of Medicine, Duke Cancer Institute
  • Berchuck, Andrew, James M. Ingram Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Choi, Steven Sok, Associate Professor of Medicine, Medicine, Gastroenterology
  • Cianciolo, George James, Associate Professor in Pathology, Pathology
  • Erickson, Harold Paul, James B. Duke Professor of Cell Biology, Biomedical Engineering
  • Gunn, Michael Dee, Professor of Medicine, Immunology
  • Hogan, Brigid L. M., George Barth Geller Professor, Cell Biology
  • Hutson, Mary Redmond, Assistant Professor of Pediatrics, Pediatrics, Neonatology
  • Krangel, Michael S., Mary Bernheim Professor of Immunology, Immunology
  • Lee, Walter T, Associate Professor of Surgery, Radiation Oncology
  • Liu, Yutao, Adjunct Assistant Professor in the Department of Medicine, Medicine, Medical Genetics
  • Milano, Carmelo Alessio, Professor of Surgery, Surgery, Cardiovascular and Thoracic Surgery
  • Palmer, Gregory M., Associate Professor of Radiation Oncology, Radiation Oncology
  • Reddy, Timothy E, Associate Professor of Biostatistics & Bioinformatics, Molecular Genetics and Microbiology
  • Sampson, John Howard, Robert H., M.D. and Gloria Wilkins Professor of Neurosurgery, in the School of Medicine, Immunology
  • Sanchez-Perez, Luis Ariel, Assistant Professor of Neurosurgery, Neurosurgery
  • Soderling, Scott Haydn, Professor in Cell Biology, Cell Biology
  • Sparks, Matthew A., Assistant Professor of Medicine, Medicine, Nephrology
  • Sunday, Mary Elizabeth Anne, Professor of Pathology, Cell Biology
  • Warner, David Samuel, Distinguished Professor of Anesthesiology, in the School of Medicine, Neurobiology